Result of FASTA (omim) for
pFN21AE3172
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3172, 403 aa
1>>>pF1KE3172 403 - 403 aa - 403 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.4992+/-0.000431; mu= 11.5848+/- 0.027
mean_var=94.6560+/-18.839, 0's: 0 Z-trim(112.6): 37 B-trim: 26 in 1/52
Lambda= 0.131826
statistics sampled from 21536 (21551) to 21536 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.605), E-opt: 0.2 (0.253), width: 16
Scan time: 8.650
The best scores are: opt bits E(85289)
NP_060289 (OMIM: 615423,616974) mitochondrial ribo ( 403) 2656 515.6 8.3e-146
NP_689505 (OMIM: 616013,616033) tRNA methyltransfe ( 339) 275 62.8 1.5e-09
NP_001128138 (OMIM: 616013,616033) tRNA methyltran ( 339) 275 62.8 1.5e-09
NP_001128137 (OMIM: 616013,616033) tRNA methyltran ( 339) 275 62.8 1.5e-09
XP_005263409 (OMIM: 616013,616033) PREDICTED: tRNA ( 339) 275 62.8 1.5e-09
XP_006714480 (OMIM: 616013,616033) PREDICTED: tRNA ( 339) 275 62.8 1.5e-09
>>NP_060289 (OMIM: 615423,616974) mitochondrial ribonucl (403 aa)
initn: 2656 init1: 2656 opt: 2656 Z-score: 2738.7 bits: 515.6 E(85289): 8.3e-146
Smith-Waterman score: 2656; 100.0% identity (100.0% similar) in 403 aa overlap (1-403:1-403)
10 20 30 40 50 60
pF1KE3 MAAFLKMSVSVNFFRPFTRFLVPFTLHRKRNNLTILQRYMSSKIPAVTYPKNESTPPSEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MAAFLKMSVSVNFFRPFTRFLVPFTLHRKRNNLTILQRYMSSKIPAVTYPKNESTPPSEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 LELDKWKTTMKSSVQEECVSTISSSKDEDPLAATREFIEMWRLLGREVPEHITEEELKTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 LELDKWKTTMKSSVQEECVSTISSSKDEDPLAATREFIEMWRLLGREVPEHITEEELKTL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 MECVSNTAKKKYLKYLYTKEKVKKARQIKKEMKAAAREEAKNIKLLETTEEDKQKNFLFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MECVSNTAKKKYLKYLYTKEKVKKARQIKKEMKAAAREEAKNIKLLETTEEDKQKNFLFL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 RLWDRNMDIAMGWKGAQAMQFGQPLVFDMAYENYMKRKELQNTVSQLLESEGWNRRNVDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 RLWDRNMDIAMGWKGAQAMQFGQPLVFDMAYENYMKRKELQNTVSQLLESEGWNRRNVDP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 FHIYFCNLKIDGALHRELVKRYQEKWDKLLLTSTEKSHVDLFPKDSIIYLTADSPNVMTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 FHIYFCNLKIDGALHRELVKRYQEKWDKLLLTSTEKSHVDLFPKDSIIYLTADSPNVMTT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 FRHDKVYVIGSFVDKSMQPGTSLAKAKRLNLATECLPLDKYLQWEIGNKNLTLDQMIRIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 FRHDKVYVIGSFVDKSMQPGTSLAKAKRLNLATECLPLDKYLQWEIGNKNLTLDQMIRIL
310 320 330 340 350 360
370 380 390 400
pF1KE3 LCLKNNGNWQEALQFVPKRKHTGFLEISQHSQEFINRLKKAKT
:::::::::::::::::::::::::::::::::::::::::::
NP_060 LCLKNNGNWQEALQFVPKRKHTGFLEISQHSQEFINRLKKAKT
370 380 390 400
>>NP_689505 (OMIM: 616013,616033) tRNA methyltransferase (339 aa)
initn: 184 init1: 152 opt: 275 Z-score: 292.6 bits: 62.8 E(85289): 1.5e-09
Smith-Waterman score: 275; 25.3% identity (62.4% similar) in 245 aa overlap (140-380:38-276)
110 120 130 140 150 160
pF1KE3 EHITEEELKTLMECVSNTAKKKYLKYLYTKEKVKKARQIKKEMKAAAREEAKNIKLLETT
: ..: ::.:: .: :: .... .
NP_689 AFIETSNVDKKQGINEDQEESQKPRLGEGCEPISK-RQMKKLIKQKQWEEQRELRKQKRK
10 20 30 40 50 60
170 180 190 200 210 220
pF1KE3 EEDKQKNFLFLRLWDRNMDIAMGWKGAQ--AMQFGQPLVFDMAYENYMKRKELQNTVSQL
:. :.:.. . : : . : .. ... :..: .... : :.... .:.
NP_689 EKRKRKKLERQCQMEPNSD-GHDRKRVRRDVVHSTLRLIIDCSFDHLMVLKDIKKLHKQI
70 80 90 100 110 120
230 240 250 260 270 280
pF1KE3 LESEGWNRRNVDPFHIYFCNLKIDGALHRELVKRYQEKWDKLLLTSTEKSHV-DLFPKDS
. . ::: . : ..:. . : :.... . .. : . . : .:. :..
NP_689 QRCYAENRRALHPVQFYLTSH--GGQLKKNM-DENDKGWVNWKDIHIKPEHYSELIKKED
130 140 150 160 170 180
290 300 310 320 330 340
pF1KE3 IIYLTADSPNVMTTFRHDKVYVIGSFVDKSMQPGTSLAKAKRLNLATECLPLDKYLQWEI
.::::.::::.. . ..:.::::..::.. . : . .:. .. ::: .... .
NP_689 LIYLTSDSPNILKELDESKAYVIGGLVDHNHHKGLTYKQASDYGINHAQLPLGNFVKMN-
190 200 210 220 230 240
350 360 370 380 390 400
pF1KE3 GNKNLTLDQMIRILLCLKNNGNWQEAL-QFVPKRKHTGFLEISQHSQEFINRLKKAKT
. : :.......:.: .. .::::. ..:.::
NP_689 SRKVLAVNHVFEIILEYLETRDWQEAFFTILPQRKGAVPTDKACESASHDNQSVRMEEGG
250 260 270 280 290 300
NP_689 SDSDSSEEEYSRNELDSPHEEKQDKENHTESTVNSLPH
310 320 330
>>NP_001128138 (OMIM: 616013,616033) tRNA methyltransfer (339 aa)
initn: 184 init1: 152 opt: 275 Z-score: 292.6 bits: 62.8 E(85289): 1.5e-09
Smith-Waterman score: 275; 25.3% identity (62.4% similar) in 245 aa overlap (140-380:38-276)
110 120 130 140 150 160
pF1KE3 EHITEEELKTLMECVSNTAKKKYLKYLYTKEKVKKARQIKKEMKAAAREEAKNIKLLETT
: ..: ::.:: .: :: .... .
NP_001 AFIETSNVDKKQGINEDQEESQKPRLGEGCEPISK-RQMKKLIKQKQWEEQRELRKQKRK
10 20 30 40 50 60
170 180 190 200 210 220
pF1KE3 EEDKQKNFLFLRLWDRNMDIAMGWKGAQ--AMQFGQPLVFDMAYENYMKRKELQNTVSQL
:. :.:.. . : : . : .. ... :..: .... : :.... .:.
NP_001 EKRKRKKLERQCQMEPNSD-GHDRKRVRRDVVHSTLRLIIDCSFDHLMVLKDIKKLHKQI
70 80 90 100 110 120
230 240 250 260 270 280
pF1KE3 LESEGWNRRNVDPFHIYFCNLKIDGALHRELVKRYQEKWDKLLLTSTEKSHV-DLFPKDS
. . ::: . : ..:. . : :.... . .. : . . : .:. :..
NP_001 QRCYAENRRALHPVQFYLTSH--GGQLKKNM-DENDKGWVNWKDIHIKPEHYSELIKKED
130 140 150 160 170 180
290 300 310 320 330 340
pF1KE3 IIYLTADSPNVMTTFRHDKVYVIGSFVDKSMQPGTSLAKAKRLNLATECLPLDKYLQWEI
.::::.::::.. . ..:.::::..::.. . : . .:. .. ::: .... .
NP_001 LIYLTSDSPNILKELDESKAYVIGGLVDHNHHKGLTYKQASDYGINHAQLPLGNFVKMN-
190 200 210 220 230 240
350 360 370 380 390 400
pF1KE3 GNKNLTLDQMIRILLCLKNNGNWQEAL-QFVPKRKHTGFLEISQHSQEFINRLKKAKT
. : :.......:.: .. .::::. ..:.::
NP_001 SRKVLAVNHVFEIILEYLETRDWQEAFFTILPQRKGAVPTDKACESASHDNQSVRMEEGG
250 260 270 280 290 300
NP_001 SDSDSSEEEYSRNELDSPHEEKQDKENHTESTVNSLPH
310 320 330
>>NP_001128137 (OMIM: 616013,616033) tRNA methyltransfer (339 aa)
initn: 184 init1: 152 opt: 275 Z-score: 292.6 bits: 62.8 E(85289): 1.5e-09
Smith-Waterman score: 275; 25.3% identity (62.4% similar) in 245 aa overlap (140-380:38-276)
110 120 130 140 150 160
pF1KE3 EHITEEELKTLMECVSNTAKKKYLKYLYTKEKVKKARQIKKEMKAAAREEAKNIKLLETT
: ..: ::.:: .: :: .... .
NP_001 AFIETSNVDKKQGINEDQEESQKPRLGEGCEPISK-RQMKKLIKQKQWEEQRELRKQKRK
10 20 30 40 50 60
170 180 190 200 210 220
pF1KE3 EEDKQKNFLFLRLWDRNMDIAMGWKGAQ--AMQFGQPLVFDMAYENYMKRKELQNTVSQL
:. :.:.. . : : . : .. ... :..: .... : :.... .:.
NP_001 EKRKRKKLERQCQMEPNSD-GHDRKRVRRDVVHSTLRLIIDCSFDHLMVLKDIKKLHKQI
70 80 90 100 110 120
230 240 250 260 270 280
pF1KE3 LESEGWNRRNVDPFHIYFCNLKIDGALHRELVKRYQEKWDKLLLTSTEKSHV-DLFPKDS
. . ::: . : ..:. . : :.... . .. : . . : .:. :..
NP_001 QRCYAENRRALHPVQFYLTSH--GGQLKKNM-DENDKGWVNWKDIHIKPEHYSELIKKED
130 140 150 160 170 180
290 300 310 320 330 340
pF1KE3 IIYLTADSPNVMTTFRHDKVYVIGSFVDKSMQPGTSLAKAKRLNLATECLPLDKYLQWEI
.::::.::::.. . ..:.::::..::.. . : . .:. .. ::: .... .
NP_001 LIYLTSDSPNILKELDESKAYVIGGLVDHNHHKGLTYKQASDYGINHAQLPLGNFVKMN-
190 200 210 220 230 240
350 360 370 380 390 400
pF1KE3 GNKNLTLDQMIRILLCLKNNGNWQEAL-QFVPKRKHTGFLEISQHSQEFINRLKKAKT
. : :.......:.: .. .::::. ..:.::
NP_001 SRKVLAVNHVFEIILEYLETRDWQEAFFTILPQRKGAVPTDKACESASHDNQSVRMEEGG
250 260 270 280 290 300
NP_001 SDSDSSEEEYSRNELDSPHEEKQDKENHTESTVNSLPH
310 320 330
>>XP_005263409 (OMIM: 616013,616033) PREDICTED: tRNA met (339 aa)
initn: 184 init1: 152 opt: 275 Z-score: 292.6 bits: 62.8 E(85289): 1.5e-09
Smith-Waterman score: 275; 25.3% identity (62.4% similar) in 245 aa overlap (140-380:38-276)
110 120 130 140 150 160
pF1KE3 EHITEEELKTLMECVSNTAKKKYLKYLYTKEKVKKARQIKKEMKAAAREEAKNIKLLETT
: ..: ::.:: .: :: .... .
XP_005 AFIETSNVDKKQGINEDQEESQKPRLGEGCEPISK-RQMKKLIKQKQWEEQRELRKQKRK
10 20 30 40 50 60
170 180 190 200 210 220
pF1KE3 EEDKQKNFLFLRLWDRNMDIAMGWKGAQ--AMQFGQPLVFDMAYENYMKRKELQNTVSQL
:. :.:.. . : : . : .. ... :..: .... : :.... .:.
XP_005 EKRKRKKLERQCQMEPNSD-GHDRKRVRRDVVHSTLRLIIDCSFDHLMVLKDIKKLHKQI
70 80 90 100 110 120
230 240 250 260 270 280
pF1KE3 LESEGWNRRNVDPFHIYFCNLKIDGALHRELVKRYQEKWDKLLLTSTEKSHV-DLFPKDS
. . ::: . : ..:. . : :.... . .. : . . : .:. :..
XP_005 QRCYAENRRALHPVQFYLTSH--GGQLKKNM-DENDKGWVNWKDIHIKPEHYSELIKKED
130 140 150 160 170 180
290 300 310 320 330 340
pF1KE3 IIYLTADSPNVMTTFRHDKVYVIGSFVDKSMQPGTSLAKAKRLNLATECLPLDKYLQWEI
.::::.::::.. . ..:.::::..::.. . : . .:. .. ::: .... .
XP_005 LIYLTSDSPNILKELDESKAYVIGGLVDHNHHKGLTYKQASDYGINHAQLPLGNFVKMN-
190 200 210 220 230 240
350 360 370 380 390 400
pF1KE3 GNKNLTLDQMIRILLCLKNNGNWQEAL-QFVPKRKHTGFLEISQHSQEFINRLKKAKT
. : :.......:.: .. .::::. ..:.::
XP_005 SRKVLAVNHVFEIILEYLETRDWQEAFFTILPQRKGAVPTDKACESASHDNQSVRMEEGG
250 260 270 280 290 300
XP_005 SDSDSSEEEYSRNELDSPHEEKQDKENHTESTVNSLPH
310 320 330
>>XP_006714480 (OMIM: 616013,616033) PREDICTED: tRNA met (339 aa)
initn: 184 init1: 152 opt: 275 Z-score: 292.6 bits: 62.8 E(85289): 1.5e-09
Smith-Waterman score: 275; 25.3% identity (62.4% similar) in 245 aa overlap (140-380:38-276)
110 120 130 140 150 160
pF1KE3 EHITEEELKTLMECVSNTAKKKYLKYLYTKEKVKKARQIKKEMKAAAREEAKNIKLLETT
: ..: ::.:: .: :: .... .
XP_006 AFIETSNVDKKQGINEDQEESQKPRLGEGCEPISK-RQMKKLIKQKQWEEQRELRKQKRK
10 20 30 40 50 60
170 180 190 200 210 220
pF1KE3 EEDKQKNFLFLRLWDRNMDIAMGWKGAQ--AMQFGQPLVFDMAYENYMKRKELQNTVSQL
:. :.:.. . : : . : .. ... :..: .... : :.... .:.
XP_006 EKRKRKKLERQCQMEPNSD-GHDRKRVRRDVVHSTLRLIIDCSFDHLMVLKDIKKLHKQI
70 80 90 100 110 120
230 240 250 260 270 280
pF1KE3 LESEGWNRRNVDPFHIYFCNLKIDGALHRELVKRYQEKWDKLLLTSTEKSHV-DLFPKDS
. . ::: . : ..:. . : :.... . .. : . . : .:. :..
XP_006 QRCYAENRRALHPVQFYLTSH--GGQLKKNM-DENDKGWVNWKDIHIKPEHYSELIKKED
130 140 150 160 170 180
290 300 310 320 330 340
pF1KE3 IIYLTADSPNVMTTFRHDKVYVIGSFVDKSMQPGTSLAKAKRLNLATECLPLDKYLQWEI
.::::.::::.. . ..:.::::..::.. . : . .:. .. ::: .... .
XP_006 LIYLTSDSPNILKELDESKAYVIGGLVDHNHHKGLTYKQASDYGINHAQLPLGNFVKMN-
190 200 210 220 230 240
350 360 370 380 390 400
pF1KE3 GNKNLTLDQMIRILLCLKNNGNWQEAL-QFVPKRKHTGFLEISQHSQEFINRLKKAKT
. : :.......:.: .. .::::. ..:.::
XP_006 SRKVLAVNHVFEIILEYLETRDWQEAFFTILPQRKGAVPTDKACESASHDNQSVRMEEGG
250 260 270 280 290 300
XP_006 SDSDSSEEEYSRNELDSPHEEKQDKENHTESTVNSLPH
310 320 330
403 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 03:19:29 2016 done: Mon Nov 7 03:19:31 2016
Total Scan time: 8.650 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]