Result of FASTA (omim) for
pFN21AE3151
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3151, 367 aa
1>>>pF1KE3151 367 - 367 aa - 367 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.4988+/-0.000392; mu= -9.1110+/- 0.025
mean_var=422.4090+/-88.290, 0's: 0 Z-trim(125.2): 4 B-trim: 1650 in 1/61
Lambda= 0.062403
statistics sampled from 48574 (48580) to 48574 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.83), E-opt: 0.2 (0.57), width: 16
Scan time: 11.050
The best scores are: opt bits E(85289)
NP_003927 (OMIM: 603764) cyclin-dependent kinase 5 ( 367) 2534 241.5 2.3e-63
NP_003876 (OMIM: 603460) cyclin-dependent kinase 5 ( 307) 820 87.1 5.6e-17
XP_011523740 (OMIM: 603460) PREDICTED: cyclin-depe ( 307) 820 87.1 5.6e-17
XP_016880770 (OMIM: 603460) PREDICTED: cyclin-depe ( 307) 820 87.1 5.6e-17
>>NP_003927 (OMIM: 603764) cyclin-dependent kinase 5 act (367 aa)
initn: 2534 init1: 2534 opt: 2534 Z-score: 1258.7 bits: 241.5 E(85289): 2.3e-63
Smith-Waterman score: 2534; 100.0% identity (100.0% similar) in 367 aa overlap (1-367:1-367)
10 20 30 40 50 60
pF1KE3 MGTVLSLSPASSAKGRRPGGLPEEKKKAPPAGDEALGGYGAPPVGKGGKGESRLKRPSVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MGTVLSLSPASSAKGRRPGGLPEEKKKAPPAGDEALGGYGAPPVGKGGKGESRLKRPSVL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 ISALTWKRLVAASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ISALTWKRLVAASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 LAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGGSPRRVIVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGGSPRRVIVQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 ASTGELLRCLGDFVCRRCYRLKELSPGELVGWFRGVDRSLLLQGWQDQAFITPANLVFVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ASTGELLRCLGDFVCRRCYRLKELSPGELVGWFRGVDRSLLLQGWQDQAFITPANLVFVY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 LLCRESLRGDELASAAELQAAFLTCLYLAYSYMGNEISYPLKPFLVEPDKERFWQRCLRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LLCRESLRGDELASAAELQAAFLTCLYLAYSYMGNEISYPLKPFLVEPDKERFWQRCLRL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 IQRLSPQMLRLNADPHFFTQVFQDLKNEGEAAASGGGPPSGGAPAASSAARDSCAAGTKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 IQRLSPQMLRLNADPHFFTQVFQDLKNEGEAAASGGGPPSGGAPAASSAARDSCAAGTKH
310 320 330 340 350 360
pF1KE3 WTMNLDR
:::::::
NP_003 WTMNLDR
>>NP_003876 (OMIM: 603460) cyclin-dependent kinase 5 act (307 aa)
initn: 959 init1: 419 opt: 820 Z-score: 425.8 bits: 87.1 E(85289): 5.6e-17
Smith-Waterman score: 956; 52.7% identity (73.2% similar) in 328 aa overlap (1-328:1-292)
10 20 30 40 50 60
pF1KE3 MGTVLSLSPASSAKGRRPGGLPEEKKKAPPAGDEALGGYGAPPVGKGGKGESRLKRPSVL
:::::::::. : . : :. : ..: : : .:..: .. ::: :.
NP_003 MGTVLSLSPS-----YRKATLFED-------GAATVGHYTAVQNSKNAK-DKNLKRHSI-
10 20 30 40
70 80 90 100 110 120
pF1KE3 ISALTWKRLVAASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKP
::.: :::.::.:::::. :::: .: :. . . . : ::: .:. . . . :.:
NP_003 ISVLPWKRIVAVSAKKKN-SKKV--QPNSSYQNN-ITHLNNENL-KKSLSCANLSTFAQP
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE3 LAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGGSPRRVIVQ
: :. : : ::.. ...: ::.. : : : . .:.:.:::::
NP_003 ---P-PAQPPA-----PPASQLSGSQTGGSSSVKKAPHPAVTS-------AGTPKRVIVQ
110 120 130 140
190 200 210 220 230 240
pF1KE3 ASTGELLRCLGDFVCRRCYRLKELSPGELVGWFRGVDRSLLLQGWQDQAFITPANLVFVY
:::.:::::::.:.::::::::.::: . : :.:.:::::::::::::.::::::.::.:
NP_003 ASTSELLRCLGEFLCRRCYRLKHLSPTDPVLWLRSVDRSLLLQGWQDQGFITPANVVFLY
150 160 170 180 190 200
250 260 270 280 290 300
pF1KE3 LLCRESLRGDELASAAELQAAFLTCLYLAYSYMGNEISYPLKPFLVEPDKERFWQRCLRL
.:::. . ..:..: ::::..::::::.:::::::::::::::::: :: ::.::: .
NP_003 MLCRDVI-SSEVGSDHELQAVLLTCLYLSYSYMGNEISYPLKPFLVESCKEAFWDRCLSV
210 220 230 240 250 260
310 320 330 340 350 360
pF1KE3 IQRLSPQMLRLNADPHFFTQVFQDLKNEGEAAASGGGPPSGGAPAASSAARDSCAAGTKH
:. .: .::..:::::.:::::.:::::
NP_003 INLMSSKMLQINADPHYFTQVFSDLKNESGQEDKKRLLLGLDR
270 280 290 300
>>XP_011523740 (OMIM: 603460) PREDICTED: cyclin-dependen (307 aa)
initn: 959 init1: 419 opt: 820 Z-score: 425.8 bits: 87.1 E(85289): 5.6e-17
Smith-Waterman score: 956; 52.7% identity (73.2% similar) in 328 aa overlap (1-328:1-292)
10 20 30 40 50 60
pF1KE3 MGTVLSLSPASSAKGRRPGGLPEEKKKAPPAGDEALGGYGAPPVGKGGKGESRLKRPSVL
:::::::::. : . : :. : ..: : : .:..: .. ::: :.
XP_011 MGTVLSLSPS-----YRKATLFED-------GAATVGHYTAVQNSKNAK-DKNLKRHSI-
10 20 30 40
70 80 90 100 110 120
pF1KE3 ISALTWKRLVAASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKP
::.: :::.::.:::::. :::: .: :. . . . : ::: .:. . . . :.:
XP_011 ISVLPWKRIVAVSAKKKN-SKKV--QPNSSYQNN-ITHLNNENL-KKSLSCANLSTFAQP
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE3 LAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGGSPRRVIVQ
: :. : : ::.. ...: ::.. : : : . .:.:.:::::
XP_011 ---P-PAQPPA-----PPASQLSGSQTGGSSSVKKAPHPAVTS-------AGTPKRVIVQ
110 120 130 140
190 200 210 220 230 240
pF1KE3 ASTGELLRCLGDFVCRRCYRLKELSPGELVGWFRGVDRSLLLQGWQDQAFITPANLVFVY
:::.:::::::.:.::::::::.::: . : :.:.:::::::::::::.::::::.::.:
XP_011 ASTSELLRCLGEFLCRRCYRLKHLSPTDPVLWLRSVDRSLLLQGWQDQGFITPANVVFLY
150 160 170 180 190 200
250 260 270 280 290 300
pF1KE3 LLCRESLRGDELASAAELQAAFLTCLYLAYSYMGNEISYPLKPFLVEPDKERFWQRCLRL
.:::. . ..:..: ::::..::::::.:::::::::::::::::: :: ::.::: .
XP_011 MLCRDVI-SSEVGSDHELQAVLLTCLYLSYSYMGNEISYPLKPFLVESCKEAFWDRCLSV
210 220 230 240 250 260
310 320 330 340 350 360
pF1KE3 IQRLSPQMLRLNADPHFFTQVFQDLKNEGEAAASGGGPPSGGAPAASSAARDSCAAGTKH
:. .: .::..:::::.:::::.:::::
XP_011 INLMSSKMLQINADPHYFTQVFSDLKNESGQEDKKRLLLGLDR
270 280 290 300
>>XP_016880770 (OMIM: 603460) PREDICTED: cyclin-dependen (307 aa)
initn: 959 init1: 419 opt: 820 Z-score: 425.8 bits: 87.1 E(85289): 5.6e-17
Smith-Waterman score: 956; 52.7% identity (73.2% similar) in 328 aa overlap (1-328:1-292)
10 20 30 40 50 60
pF1KE3 MGTVLSLSPASSAKGRRPGGLPEEKKKAPPAGDEALGGYGAPPVGKGGKGESRLKRPSVL
:::::::::. : . : :. : ..: : : .:..: .. ::: :.
XP_016 MGTVLSLSPS-----YRKATLFED-------GAATVGHYTAVQNSKNAK-DKNLKRHSI-
10 20 30 40
70 80 90 100 110 120
pF1KE3 ISALTWKRLVAASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKP
::.: :::.::.:::::. :::: .: :. . . . : ::: .:. . . . :.:
XP_016 ISVLPWKRIVAVSAKKKN-SKKV--QPNSSYQNN-ITHLNNENL-KKSLSCANLSTFAQP
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE3 LAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGGSPRRVIVQ
: :. : : ::.. ...: ::.. : : : . .:.:.:::::
XP_016 ---P-PAQPPA-----PPASQLSGSQTGGSSSVKKAPHPAVTS-------AGTPKRVIVQ
110 120 130 140
190 200 210 220 230 240
pF1KE3 ASTGELLRCLGDFVCRRCYRLKELSPGELVGWFRGVDRSLLLQGWQDQAFITPANLVFVY
:::.:::::::.:.::::::::.::: . : :.:.:::::::::::::.::::::.::.:
XP_016 ASTSELLRCLGEFLCRRCYRLKHLSPTDPVLWLRSVDRSLLLQGWQDQGFITPANVVFLY
150 160 170 180 190 200
250 260 270 280 290 300
pF1KE3 LLCRESLRGDELASAAELQAAFLTCLYLAYSYMGNEISYPLKPFLVEPDKERFWQRCLRL
.:::. . ..:..: ::::..::::::.:::::::::::::::::: :: ::.::: .
XP_016 MLCRDVI-SSEVGSDHELQAVLLTCLYLSYSYMGNEISYPLKPFLVESCKEAFWDRCLSV
210 220 230 240 250 260
310 320 330 340 350 360
pF1KE3 IQRLSPQMLRLNADPHFFTQVFQDLKNEGEAAASGGGPPSGGAPAASSAARDSCAAGTKH
:. .: .::..:::::.:::::.:::::
XP_016 INLMSSKMLQINADPHYFTQVFSDLKNESGQEDKKRLLLGLDR
270 280 290 300
367 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 18:01:40 2016 done: Sun Nov 6 18:01:42 2016
Total Scan time: 11.050 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]