Result of FASTA (ccds) for
pFN21AE3150
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3150, 358 aa
1>>>pF1KE3150 358 - 358 aa - 358 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4299+/-0.000845; mu= 16.0751+/- 0.051
mean_var=66.6765+/-13.314, 0's: 0 Z-trim(106.2): 15 B-trim: 0 in 0/51
Lambda= 0.157068
statistics sampled from 8860 (8869) to 8860 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.649), E-opt: 0.2 (0.272), width: 16
Scan time: 1.960
The best scores are: opt bits E(32554)
CCDS5952.1 FBXO25 gene_id:26260|Hs108|chr8 ( 358) 2497 574.6 4.4e-164
CCDS5953.1 FBXO25 gene_id:26260|Hs108|chr8 ( 367) 2284 526.4 1.5e-149
CCDS5954.1 FBXO25 gene_id:26260|Hs108|chr8 ( 291) 1815 420.0 1.2e-117
CCDS6345.1 FBXO32 gene_id:114907|Hs108|chr8 ( 355) 1547 359.3 2.8e-99
CCDS56553.1 FBXO32 gene_id:114907|Hs108|chr8 ( 262) 618 148.8 5e-36
>>CCDS5952.1 FBXO25 gene_id:26260|Hs108|chr8 (358 aa)
initn: 2497 init1: 2497 opt: 2497 Z-score: 3059.3 bits: 574.6 E(32554): 4.4e-164
Smith-Waterman score: 2497; 99.7% identity (100.0% similar) in 358 aa overlap (1-358:1-358)
10 20 30 40 50 60
pF1KE3 MPFLGQDWRSPGWSWIKTEDGWKRCESCSQKLERENNHCNISHSIILNSEDGEIFNNEEH
:::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::
CCDS59 MPFLGQDWRSPGWSWIKTEDGWKRCESCSQKLERENNRCNISHSIILNSEDGEIFNNEEH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 EYASKKRKKDHFRNDTNTQSFYREKWIYVHKESTKERHGYCTLGEAFNRLDFSSAIQDIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 EYASKKRKKDHFRNDTNTQSFYREKWIYVHKESTKERHGYCTLGEAFNRLDFSSAIQDIR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 RFNYVVKLLQLIAKSQLTSLSGVAQKNYFNILDKIVQKVLDDHHNPRLIKDLLQDLSSTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 RFNYVVKLLQLIAKSQLTSLSGVAQKNYFNILDKIVQKVLDDHHNPRLIKDLLQDLSSTL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 CILIRGVGKSVLVGNINIWICRLETILAWQQQLQDLQMTKQVNNGLTLSDLPLHMLNNIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 CILIRGVGKSVLVGNINIWICRLETILAWQQQLQDLQMTKQVNNGLTLSDLPLHMLNNIL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 YRFSDGWDIITLGQVTPTLYMLSEDRQLWKKLCQYHFAEKQFCRHLILSEKGHIEWKLMY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 YRFSDGWDIITLGQVTPTLYMLSEDRQLWKKLCQYHFAEKQFCRHLILSEKGHIEWKLMY
250 260 270 280 290 300
310 320 330 340 350
pF1KE3 FALQKHYPAKEQYGDTLHFCRHCSILFWKDSGHPCTAADPDSCFTPVSPQHFIDLFKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 FALQKHYPAKEQYGDTLHFCRHCSILFWKDSGHPCTAADPDSCFTPVSPQHFIDLFKF
310 320 330 340 350
>>CCDS5953.1 FBXO25 gene_id:26260|Hs108|chr8 (367 aa)
initn: 2284 init1: 2284 opt: 2284 Z-score: 2798.3 bits: 526.4 E(32554): 1.5e-149
Smith-Waterman score: 2469; 97.3% identity (97.5% similar) in 367 aa overlap (1-358:1-367)
10 20 30 40 50 60
pF1KE3 MPFLGQDWRSPGWSWIKTEDGWKRCESCSQKLERENNHCNISHSIILNSEDGEIFNNEEH
:::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::
CCDS59 MPFLGQDWRSPGWSWIKTEDGWKRCESCSQKLERENNRCNISHSIILNSEDGEIFNNEEH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 EYASKKRKKDHFRNDTNTQSFYREKWIYVHKESTKERHGYCTLGEAFNRLDFSSAIQDIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 EYASKKRKKDHFRNDTNTQSFYREKWIYVHKESTKERHGYCTLGEAFNRLDFSSAIQDIR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 RFNYVVKLLQLIAKSQLTSLSGVAQKNYFNILDKIVQKVLDDHHNPRLIKDLLQDLSSTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 RFNYVVKLLQLIAKSQLTSLSGVAQKNYFNILDKIVQKVLDDHHNPRLIKDLLQDLSSTL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 CILIRGVGKSVLVGNINIWICRLETILAWQQQLQDLQMTKQVNNGLTLSDLPLHMLNNIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 CILIRGVGKSVLVGNINIWICRLETILAWQQQLQDLQMTKQVNNGLTLSDLPLHMLNNIL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 YRFSDGWDIITLGQVTPTLYMLSEDRQLWKKLCQYHFAEKQFCRHLILSEKGHIEWKLMY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 YRFSDGWDIITLGQVTPTLYMLSEDRQLWKKLCQYHFAEKQFCRHLILSEKGHIEWKLMY
250 260 270 280 290 300
310 320 330 340 350
pF1KE3 FALQKHYPAKEQYGDTLHFCRHCSILFWKD---------SGHPCTAADPDSCFTPVSPQH
:::::::::::::::::::::::::::::: :::::::::::::::::::::
CCDS59 FALQKHYPAKEQYGDTLHFCRHCSILFWKDYHLALLFKDSGHPCTAADPDSCFTPVSPQH
310 320 330 340 350 360
pF1KE3 FIDLFKF
:::::::
CCDS59 FIDLFKF
>>CCDS5954.1 FBXO25 gene_id:26260|Hs108|chr8 (291 aa)
initn: 1813 init1: 1813 opt: 1815 Z-score: 2225.5 bits: 420.0 E(32554): 1.2e-117
Smith-Waterman score: 1815; 94.0% identity (97.2% similar) in 283 aa overlap (78-358:9-291)
50 60 70 80 90 100
pF1KE3 NSEDGEIFNNEEHEYASKKRKKDHFRNDTNTQSFYREKWIYVHKESTK--ERHGYCTLGE
.....:.: . : :. .:::::::::
CCDS59 MEKYSIMKSMNMHRKKGKRTILEMTQILKRHGYCTLGE
10 20 30
110 120 130 140 150 160
pF1KE3 AFNRLDFSSAIQDIRRFNYVVKLLQLIAKSQLTSLSGVAQKNYFNILDKIVQKVLDDHHN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 AFNRLDFSSAIQDIRRFNYVVKLLQLIAKSQLTSLSGVAQKNYFNILDKIVQKVLDDHHN
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE3 PRLIKDLLQDLSSTLCILIRGVGKSVLVGNINIWICRLETILAWQQQLQDLQMTKQVNNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 PRLIKDLLQDLSSTLCILIRGVGKSVLVGNINIWICRLETILAWQQQLQDLQMTKQVNNG
100 110 120 130 140 150
230 240 250 260 270 280
pF1KE3 LTLSDLPLHMLNNILYRFSDGWDIITLGQVTPTLYMLSEDRQLWKKLCQYHFAEKQFCRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 LTLSDLPLHMLNNILYRFSDGWDIITLGQVTPTLYMLSEDRQLWKKLCQYHFAEKQFCRH
160 170 180 190 200 210
290 300 310 320 330 340
pF1KE3 LILSEKGHIEWKLMYFALQKHYPAKEQYGDTLHFCRHCSILFWKDSGHPCTAADPDSCFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 LILSEKGHIEWKLMYFALQKHYPAKEQYGDTLHFCRHCSILFWKDSGHPCTAADPDSCFT
220 230 240 250 260 270
350
pF1KE3 PVSPQHFIDLFKF
:::::::::::::
CCDS59 PVSPQHFIDLFKF
280 290
>>CCDS6345.1 FBXO32 gene_id:114907|Hs108|chr8 (355 aa)
initn: 1545 init1: 1388 opt: 1547 Z-score: 1895.9 bits: 359.3 E(32554): 2.8e-99
Smith-Waterman score: 1547; 61.4% identity (84.2% similar) in 360 aa overlap (1-358:1-355)
10 20 30 40 50
pF1KE3 MPFLGQDWRSPGWSWIKTEDGWKRC--ESCSQKLERENNHCNISHSIILNSEDGEIFNNE
:::::::::::: .:.:: ::::: :. .. . ...:: . . :.:. .::.
CCDS63 MPFLGQDWRSPGQNWVKTADGWKRFLDEKSGSFVSDLSSYCN---KEVYNKEN--LFNSL
10 20 30 40 50
60 70 80 90 100 110
pF1KE3 EHEYASKKRKKDHFRNDTNTQSFYREKWIYVHKESTKERHGYCTLGEAFNRLDFSSAIQD
... :.:::::: . . :.:: :..:::::::: :::::::::::::::::::::.:: :
CCDS63 NYDVAAKKRKKDMLNSKTKTQYFHQEKWIYVHKGSTKERHGYCTLGEAFNRLDFSTAILD
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE3 IRRFNYVVKLLQLIAKSQLTSLSGVAQKNYFNILDKIVQKVLDDHHNPRLIKDLLQDLSS
:::::::.::.::::::::::::.::::..:::.:.: :::.:..: :::..::: : .
CCDS63 SRRFNYVVRLLELIAKSQLTSLSGIAQKNFMNILEKVVLKVLEDQQNIRLIRELLQTLYT
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE3 TLCILIRGVGKSVLVGNINIWICRLETILAWQQQLQDLQMTKQVNNGLTLSDLPLHMLNN
.:: :.. :::::::::::.:. :.:::: :::::...:.:. . .:::..:::: . :
CCDS63 SLCTLVQRVGKSVLVGNINMWVYRMETILHWQQQLNNIQITRPAFKGLTFTDLPLCLQLN
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE3 ILYRFSDGWDIITLGQVTPTLYMLSEDRQLWKKLCQYHFAEKQFCRHLILSEKGHIEWKL
:. :.::: :...:::..: :..::::: ::::::::::.:.:. ..::::.::...::
CCDS63 IMQRLSDGRDLVSLGQAAPDLHVLSEDRLLWKKLCQYHFSERQIRKRLILSDKGQLDWKK
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE3 MYFALQKHYPAKEQYGDTLHFCRHCSILFWKDSGHPCTAADPDSCFTPVSPQHFIDLFKF
::: : . :: ::::::::..:.:: :: :: . ::::: .:.:: . .::: ::.::::
CCDS63 MYFKLVRCYPRKEQYGDTLQLCKHCHILSWKGTDHPCTANNPESCSVSLSPQDFINLFKF
300 310 320 330 340 350
>>CCDS56553.1 FBXO32 gene_id:114907|Hs108|chr8 (262 aa)
initn: 1115 init1: 618 opt: 618 Z-score: 760.3 bits: 148.8 E(32554): 5e-36
Smith-Waterman score: 936; 44.4% identity (60.8% similar) in 360 aa overlap (1-358:1-262)
10 20 30 40 50
pF1KE3 MPFLGQDWRSPGWSWIKTEDGWKRC--ESCSQKLERENNHCNISHSIILNSEDGEIFNNE
:::::::::::: .:.:: ::::: :. .. . ...:: . . :.:. .::.
CCDS56 MPFLGQDWRSPGQNWVKTADGWKRFLDEKSGSFVSDLSSYCN---KEVYNKEN--LFNSL
10 20 30 40 50
60 70 80 90 100 110
pF1KE3 EHEYASKKRKKDHFRNDTNTQSFYREKWIYVHKESTKERHGYCTLGEAFNRLDFSSAIQD
... :.:::::: . . :.:: :..:::::::: :::::::::::::::::::::.:: :
CCDS56 NYDVAAKKRKKDMLNSKTKTQYFHQEKWIYVHKGSTKERHGYCTLGEAFNRLDFSTAILD
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE3 IRRFNYVVKLLQLIAKSQLTSLSGVAQKNYFNILDKIVQKVLDDHHNPRLIKDLLQDLSS
:::::::. : .
CCDS56 SRRFNYVVR--------------------------------------PAF----------
120
180 190 200 210 220 230
pF1KE3 TLCILIRGVGKSVLVGNINIWICRLETILAWQQQLQDLQMTKQVNNGLTLSDLPLHMLNN
.:::..:::: . :
CCDS56 ---------------------------------------------KGLTFTDLPLCLQLN
130 140
240 250 260 270 280 290
pF1KE3 ILYRFSDGWDIITLGQVTPTLYMLSEDRQLWKKLCQYHFAEKQFCRHLILSEKGHIEWKL
:. :.::: :...:::..: :..::::: ::::::::::.:.:. ..::::.::...::
CCDS56 IMQRLSDGRDLVSLGQAAPDLHVLSEDRLLWKKLCQYHFSERQIRKRLILSDKGQLDWKK
150 160 170 180 190 200
300 310 320 330 340 350
pF1KE3 MYFALQKHYPAKEQYGDTLHFCRHCSILFWKDSGHPCTAADPDSCFTPVSPQHFIDLFKF
::: : . :: ::::::::..:.:: :: :: . ::::: .:.:: . .::: ::.::::
CCDS56 MYFKLVRCYPRKEQYGDTLQLCKHCHILSWKGTDHPCTANNPESCSVSLSPQDFINLFKF
210 220 230 240 250 260
358 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 19:07:00 2016 done: Mon Nov 7 19:07:00 2016
Total Scan time: 1.960 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]