Result of FASTA (omim) for
pFN21AE3143
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3143, 353 aa
1>>>pF1KE3143 353 - 353 aa - 353 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.3955+/-0.000404; mu= 8.4233+/- 0.025
mean_var=170.0286+/-34.029, 0's: 0 Z-trim(117.4): 146 B-trim: 1454 in 2/55
Lambda= 0.098359
statistics sampled from 29178 (29333) to 29178 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.69), E-opt: 0.2 (0.344), width: 16
Scan time: 8.750
The best scores are: opt bits E(85289)
NP_115977 (OMIM: 606131) E3 ubiquitin-protein liga ( 353) 2363 347.3 3.1e-95
XP_016858048 (OMIM: 606131) PREDICTED: E3 ubiquiti ( 379) 2348 345.2 1.4e-94
NP_908974 (OMIM: 606469) tripartite motif-containi ( 452) 1449 217.7 4.1e-56
XP_011515918 (OMIM: 606469) PREDICTED: tripartite ( 452) 1449 217.7 4.1e-56
XP_011515917 (OMIM: 606469) PREDICTED: tripartite ( 540) 1449 217.7 4.7e-56
NP_149047 (OMIM: 606469) tripartite motif-containi ( 540) 1449 217.7 4.7e-56
NP_908973 (OMIM: 606469) tripartite motif-containi ( 548) 1449 217.7 4.7e-56
XP_011515915 (OMIM: 606469) PREDICTED: tripartite ( 548) 1449 217.7 4.7e-56
XP_011515916 (OMIM: 606469) PREDICTED: tripartite ( 548) 1449 217.7 4.7e-56
XP_005251373 (OMIM: 606469) PREDICTED: tripartite ( 547) 1446 217.3 6.3e-56
NP_912730 (OMIM: 606474) tripartite motif-containi ( 358) 1437 215.9 1.1e-55
XP_016869397 (OMIM: 606469) PREDICTED: tripartite ( 479) 1111 169.7 1.2e-41
NP_908975 (OMIM: 606469) tripartite motif-containi ( 241) 1020 156.5 5.5e-38
NP_115935 (OMIM: 606474) tripartite motif-containi ( 400) 937 145.0 2.8e-34
XP_016869398 (OMIM: 606469) PREDICTED: tripartite ( 426) 809 126.8 8.5e-29
XP_011515919 (OMIM: 606469) PREDICTED: tripartite ( 426) 809 126.8 8.5e-29
NP_001269308 (OMIM: 600986) tripartite motif-conta ( 551) 363 63.6 1.2e-09
NP_001269307 (OMIM: 600986) tripartite motif-conta ( 633) 363 63.7 1.3e-09
NP_001243528 (OMIM: 600986) tripartite motif-conta ( 736) 363 63.7 1.4e-09
NP_001243530 (OMIM: 600986) tripartite motif-conta ( 746) 363 63.8 1.4e-09
XP_016857882 (OMIM: 600986) PREDICTED: tripartite ( 746) 363 63.8 1.4e-09
NP_079334 (OMIM: 600986) tripartite motif-containi ( 759) 363 63.8 1.5e-09
XP_011508304 (OMIM: 600986) PREDICTED: tripartite ( 788) 363 63.8 1.5e-09
XP_016865112 (OMIM: 609317) PREDICTED: E3 ubiquiti ( 529) 334 59.5 2e-08
NP_001287681 (OMIM: 609317) E3 ubiquitin-protein l ( 573) 334 59.5 2.1e-08
NP_001287688 (OMIM: 609317) E3 ubiquitin-protein l ( 716) 334 59.6 2.4e-08
NP_061170 (OMIM: 609317) E3 ubiquitin-protein liga ( 728) 334 59.6 2.5e-08
XP_016865111 (OMIM: 609317) PREDICTED: E3 ubiquiti ( 733) 334 59.6 2.5e-08
XP_016865110 (OMIM: 609317) PREDICTED: E3 ubiquiti ( 745) 334 59.6 2.5e-08
NP_001180208 (OMIM: 189960,300000,300552) E3 ubiqu ( 489) 319 57.3 8.1e-08
XP_016885031 (OMIM: 189960,300000,300552) PREDICTE ( 489) 319 57.3 8.1e-08
XP_016885029 (OMIM: 189960,300000,300552) PREDICTE ( 552) 319 57.4 8.8e-08
NP_001180206 (OMIM: 189960,300000,300552) E3 ubiqu ( 667) 319 57.5 1e-07
NP_001092094 (OMIM: 189960,300000,300552) E3 ubiqu ( 667) 319 57.5 1e-07
NP_150632 (OMIM: 189960,300000,300552) E3 ubiquiti ( 667) 319 57.5 1e-07
XP_016885025 (OMIM: 189960,300000,300552) PREDICTE ( 667) 319 57.5 1e-07
NP_000372 (OMIM: 189960,300000,300552) E3 ubiquiti ( 667) 319 57.5 1e-07
NP_001287818 (OMIM: 610584) tripartite motif-conta ( 721) 315 56.9 1.6e-07
XP_011542494 (OMIM: 610584) PREDICTED: tripartite ( 781) 315 57.0 1.7e-07
NP_001004342 (OMIM: 610584) tripartite motif-conta ( 783) 315 57.0 1.7e-07
XP_016856812 (OMIM: 610584) PREDICTED: tripartite ( 854) 315 57.0 1.8e-07
NP_443210 (OMIM: 606555) E3 ubiquitin-protein liga ( 550) 296 54.1 8.4e-07
XP_016876439 (OMIM: 606555) PREDICTED: E3 ubiquiti ( 593) 296 54.2 8.9e-07
XP_016876438 (OMIM: 606555) PREDICTED: E3 ubiquiti ( 611) 296 54.2 9.1e-07
XP_016876437 (OMIM: 606555) PREDICTED: E3 ubiquiti ( 688) 296 54.2 9.9e-07
XP_016876436 (OMIM: 606555) PREDICTED: E3 ubiquiti ( 692) 296 54.2 1e-06
XP_016876435 (OMIM: 606555) PREDICTED: E3 ubiquiti ( 706) 296 54.2 1e-06
NP_055978 (OMIM: 606555) E3 ubiquitin-protein liga ( 710) 296 54.2 1e-06
XP_016876434 (OMIM: 606555) PREDICTED: E3 ubiquiti ( 710) 296 54.2 1e-06
XP_005267359 (OMIM: 606555) PREDICTED: E3 ubiquiti ( 714) 296 54.2 1e-06
>>NP_115977 (OMIM: 606131) E3 ubiquitin-protein ligase T (353 aa)
initn: 2363 init1: 2363 opt: 2363 Z-score: 1830.8 bits: 347.3 E(85289): 3.1e-95
Smith-Waterman score: 2363; 100.0% identity (100.0% similar) in 353 aa overlap (1-353:1-353)
10 20 30 40 50 60
pF1KE3 MDYKSSLIQDGNPMENLEKQLICPICLEMFTKPVVILPCQHNLCRKCANDIFQAANPYWT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 MDYKSSLIQDGNPMENLEKQLICPICLEMFTKPVVILPCQHNLCRKCANDIFQAANPYWT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 SRGSSVSMSGGRFRCPTCRHEVIMDRHGVYGLQRNLLVENIIDIYKQECSSRPLQKGSHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 SRGSSVSMSGGRFRCPTCRHEVIMDRHGVYGLQRNLLVENIIDIYKQECSSRPLQKGSHP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 MCKEHEDEKINIYCLTCEVPTCSMCKVFGIHKACEVAPLQSVFQGQKTELNNCISMLVAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 MCKEHEDEKINIYCLTCEVPTCSMCKVFGIHKACEVAPLQSVFQGQKTELNNCISMLVAG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 NDRVQTIITQLEDSRRVTKENSHQVKEELSQKFDTLYAILDEKKSELLQRITQEQEKKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 NDRVQTIITQLEDSRRVTKENSHQVKEELSQKFDTLYAILDEKKSELLQRITQEQEKKLS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 FIEALIQQYQEQLDKSTKLVETAIQSLDEPGGATFLLTAKQLIKSIVEASKGCQLGKTEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 FIEALIQQYQEQLDKSTKLVETAIQSLDEPGGATFLLTAKQLIKSIVEASKGCQLGKTEQ
250 260 270 280 290 300
310 320 330 340 350
pF1KE3 GFENMDFFTLDLEHIADALRAIDFGTDEEEEEFIEEEDQEEEESTEGKEEGHQ
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 GFENMDFFTLDLEHIADALRAIDFGTDEEEEEFIEEEDQEEEESTEGKEEGHQ
310 320 330 340 350
>>XP_016858048 (OMIM: 606131) PREDICTED: E3 ubiquitin-pr (379 aa)
initn: 2504 init1: 2348 opt: 2348 Z-score: 1818.9 bits: 345.2 E(85289): 1.4e-94
Smith-Waterman score: 2348; 99.4% identity (100.0% similar) in 353 aa overlap (1-353:1-353)
10 20 30 40 50 60
pF1KE3 MDYKSSLIQDGNPMENLEKQLICPICLEMFTKPVVILPCQHNLCRKCANDIFQAANPYWT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDYKSSLIQDGNPMENLEKQLICPICLEMFTKPVVILPCQHNLCRKCANDIFQAANPYWT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 SRGSSVSMSGGRFRCPTCRHEVIMDRHGVYGLQRNLLVENIIDIYKQECSSRPLQKGSHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRGSSVSMSGGRFRCPTCRHEVIMDRHGVYGLQRNLLVENIIDIYKQECSSRPLQKGSHP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 MCKEHEDEKINIYCLTCEVPTCSMCKVFGIHKACEVAPLQSVFQGQKTELNNCISMLVAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MCKEHEDEKINIYCLTCEVPTCSMCKVFGIHKACEVAPLQSVFQGQKTELNNCISMLVAG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 NDRVQTIITQLEDSRRVTKENSHQVKEELSQKFDTLYAILDEKKSELLQRITQEQEKKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NDRVQTIITQLEDSRRVTKENSHQVKEELSQKFDTLYAILDEKKSELLQRITQEQEKKLS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 FIEALIQQYQEQLDKSTKLVETAIQSLDEPGGATFLLTAKQLIKSIVEASKGCQLGKTEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FIEALIQQYQEQLDKSTKLVETAIQSLDEPGGATFLLTAKQLIKSIVEASKGCQLGKTEQ
250 260 270 280 290 300
310 320 330 340 350
pF1KE3 GFENMDFFTLDLEHIADALRAIDFGTDEEEEEFIEEEDQEEEESTEGKEEGHQ
:::::::::::::::::::::::::::::::::::::::::::::::::::..
XP_016 GFENMDFFTLDLEHIADALRAIDFGTDEEEEEFIEEEDQEEEESTEGKEEGKKFIYLHSF
310 320 330 340 350 360
XP_016 VPSFIPQQSEVPTVCEALC
370
>>NP_908974 (OMIM: 606469) tripartite motif-containing p (452 aa)
initn: 864 init1: 820 opt: 1449 Z-score: 1128.4 bits: 217.7 E(85289): 4.1e-56
Smith-Waterman score: 1449; 60.4% identity (84.3% similar) in 351 aa overlap (1-351:5-345)
10 20 30 40 50
pF1KE3 MDYKSSLIQDGNPMENLEKQLICPICLEMFTKPVVILPCQHNLCRKCANDIFQAAN
..::: . .. . :.:::::::::::::::::::::::::::::::::.:::::.:
NP_908 MSASLNYKS-FSKEQQTMDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCASDIFQASN
10 20 30 40 50
60 70 80 90 100 110
pF1KE3 PYWTSRGSSVSMSGGRFRCPTCRHEVIMDRHGVYGLQRNLLVENIIDIYKQECSSRPLQK
:: .::... ::::::::.:::::..:::::::::::::::::::::::: :.:: .:
NP_908 PYLPTRGGTTMASGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQE-STRPEKK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE3 GSHPMCKEHEDEKINIYCLTCEVPTCSMCKVFGIHKACEVAPLQSVFQGQKTELNNCISM
...:::.:::.:.::::::.:::::::.::::: :: :.:::: ::: ::.::.. :..
NP_908 SDQPMCEEHEEERINIYCLNCEVPTCSLCKVFGAHKDCQVAPLTHVFQRQKSELSDGIAI
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE3 LVAGNDRVQTIITQLEDSRRVTKENSHQVKEELSQKFDTLYAILDEKKSELLQRITQEQE
::..::::: .:.::::. .. .: .. :.:: .::: ::.::.:.:.:. : ::. ::
NP_908 LVGSNDRVQGVISQLEDTCKTIEECCRKQKQELCEKFDYLYGILEERKNEMTQVITRTQE
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE3 KKLSFIEALIQQYQEQLDKSTKLVETAIQSLDEPGGATFLLTAKQLIKSIVEASKGCQLG
.:: ..:::..:...:.. .::::..:: .::: :.:: .:: :.:.: ::::. :.
NP_908 EKLEHVRALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTLLKKISEASKAFQME
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE3 KTEQGFENMDFFTLDLEHIADALRAIDFGTDEEEEEFIEEEDQEEEESTEGKEEGHQ
: :.:.:::. ::..:.. .: ::: . :.::.::::. ::..::
NP_908 KIEHGYENMNHFTVNLNREEKIIREIDF--------YREDEDEEEEEGGEGEKEGEGEVG
300 310 320 330 340 350
NP_908 GEAVEVEEVENVQTEFPGEDENPEKASELSQVELQAAPGALPVSSPEPPPALPPAADAPV
360 370 380 390 400 410
>>XP_011515918 (OMIM: 606469) PREDICTED: tripartite moti (452 aa)
initn: 864 init1: 820 opt: 1449 Z-score: 1128.4 bits: 217.7 E(85289): 4.1e-56
Smith-Waterman score: 1449; 60.4% identity (84.3% similar) in 351 aa overlap (1-351:5-345)
10 20 30 40 50
pF1KE3 MDYKSSLIQDGNPMENLEKQLICPICLEMFTKPVVILPCQHNLCRKCANDIFQAAN
..::: . .. . :.:::::::::::::::::::::::::::::::::.:::::.:
XP_011 MSASLNYKS-FSKEQQTMDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCASDIFQASN
10 20 30 40 50
60 70 80 90 100 110
pF1KE3 PYWTSRGSSVSMSGGRFRCPTCRHEVIMDRHGVYGLQRNLLVENIIDIYKQECSSRPLQK
:: .::... ::::::::.:::::..:::::::::::::::::::::::: :.:: .:
XP_011 PYLPTRGGTTMASGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQE-STRPEKK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE3 GSHPMCKEHEDEKINIYCLTCEVPTCSMCKVFGIHKACEVAPLQSVFQGQKTELNNCISM
...:::.:::.:.::::::.:::::::.::::: :: :.:::: ::: ::.::.. :..
XP_011 SDQPMCEEHEEERINIYCLNCEVPTCSLCKVFGAHKDCQVAPLTHVFQRQKSELSDGIAI
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE3 LVAGNDRVQTIITQLEDSRRVTKENSHQVKEELSQKFDTLYAILDEKKSELLQRITQEQE
::..::::: .:.::::. .. .: .. :.:: .::: ::.::.:.:.:. : ::. ::
XP_011 LVGSNDRVQGVISQLEDTCKTIEECCRKQKQELCEKFDYLYGILEERKNEMTQVITRTQE
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE3 KKLSFIEALIQQYQEQLDKSTKLVETAIQSLDEPGGATFLLTAKQLIKSIVEASKGCQLG
.:: ..:::..:...:.. .::::..:: .::: :.:: .:: :.:.: ::::. :.
XP_011 EKLEHVRALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTLLKKISEASKAFQME
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE3 KTEQGFENMDFFTLDLEHIADALRAIDFGTDEEEEEFIEEEDQEEEESTEGKEEGHQ
: :.:.:::. ::..:.. .: ::: . :.::.::::. ::..::
XP_011 KIEHGYENMNHFTVNLNREEKIIREIDF--------YREDEDEEEEEGGEGEKEGEGEVG
300 310 320 330 340 350
XP_011 GEAVEVEEVENVQTEFPGEDENPEKASELSQVELQAAPGALPVSSPEPPPALPPAADAPV
360 370 380 390 400 410
>>XP_011515917 (OMIM: 606469) PREDICTED: tripartite moti (540 aa)
initn: 843 init1: 820 opt: 1449 Z-score: 1127.4 bits: 217.7 E(85289): 4.7e-56
Smith-Waterman score: 1449; 60.4% identity (84.3% similar) in 351 aa overlap (1-351:5-345)
10 20 30 40 50
pF1KE3 MDYKSSLIQDGNPMENLEKQLICPICLEMFTKPVVILPCQHNLCRKCANDIFQAAN
..::: . .. . :.:::::::::::::::::::::::::::::::::.:::::.:
XP_011 MSASLNYKS-FSKEQQTMDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCASDIFQASN
10 20 30 40 50
60 70 80 90 100 110
pF1KE3 PYWTSRGSSVSMSGGRFRCPTCRHEVIMDRHGVYGLQRNLLVENIIDIYKQECSSRPLQK
:: .::... ::::::::.:::::..:::::::::::::::::::::::: :.:: .:
XP_011 PYLPTRGGTTMASGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQE-STRPEKK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE3 GSHPMCKEHEDEKINIYCLTCEVPTCSMCKVFGIHKACEVAPLQSVFQGQKTELNNCISM
...:::.:::.:.::::::.:::::::.::::: :: :.:::: ::: ::.::.. :..
XP_011 SDQPMCEEHEEERINIYCLNCEVPTCSLCKVFGAHKDCQVAPLTHVFQRQKSELSDGIAI
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE3 LVAGNDRVQTIITQLEDSRRVTKENSHQVKEELSQKFDTLYAILDEKKSELLQRITQEQE
::..::::: .:.::::. .. .: .. :.:: .::: ::.::.:.:.:. : ::. ::
XP_011 LVGSNDRVQGVISQLEDTCKTIEECCRKQKQELCEKFDYLYGILEERKNEMTQVITRTQE
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE3 KKLSFIEALIQQYQEQLDKSTKLVETAIQSLDEPGGATFLLTAKQLIKSIVEASKGCQLG
.:: ..:::..:...:.. .::::..:: .::: :.:: .:: :.:.: ::::. :.
XP_011 EKLEHVRALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTLLKKISEASKAFQME
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE3 KTEQGFENMDFFTLDLEHIADALRAIDFGTDEEEEEFIEEEDQEEEESTEGKEEGHQ
: :.:.:::. ::..:.. .: ::: . :.::.::::. ::..::
XP_011 KIEHGYENMNHFTVNLNREEKIIREIDF--------YREDEDEEEEEGGEGEKEGEGEVG
300 310 320 330 340 350
XP_011 GEAVEVEEVENVQTEFPGEDENPEKASELSQVELQAAPGALPVSSPEPPPALPPAADAPV
360 370 380 390 400 410
>>NP_149047 (OMIM: 606469) tripartite motif-containing p (540 aa)
initn: 843 init1: 820 opt: 1449 Z-score: 1127.4 bits: 217.7 E(85289): 4.7e-56
Smith-Waterman score: 1449; 60.4% identity (84.3% similar) in 351 aa overlap (1-351:5-345)
10 20 30 40 50
pF1KE3 MDYKSSLIQDGNPMENLEKQLICPICLEMFTKPVVILPCQHNLCRKCANDIFQAAN
..::: . .. . :.:::::::::::::::::::::::::::::::::.:::::.:
NP_149 MSASLNYKS-FSKEQQTMDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCASDIFQASN
10 20 30 40 50
60 70 80 90 100 110
pF1KE3 PYWTSRGSSVSMSGGRFRCPTCRHEVIMDRHGVYGLQRNLLVENIIDIYKQECSSRPLQK
:: .::... ::::::::.:::::..:::::::::::::::::::::::: :.:: .:
NP_149 PYLPTRGGTTMASGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQE-STRPEKK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE3 GSHPMCKEHEDEKINIYCLTCEVPTCSMCKVFGIHKACEVAPLQSVFQGQKTELNNCISM
...:::.:::.:.::::::.:::::::.::::: :: :.:::: ::: ::.::.. :..
NP_149 SDQPMCEEHEEERINIYCLNCEVPTCSLCKVFGAHKDCQVAPLTHVFQRQKSELSDGIAI
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE3 LVAGNDRVQTIITQLEDSRRVTKENSHQVKEELSQKFDTLYAILDEKKSELLQRITQEQE
::..::::: .:.::::. .. .: .. :.:: .::: ::.::.:.:.:. : ::. ::
NP_149 LVGSNDRVQGVISQLEDTCKTIEECCRKQKQELCEKFDYLYGILEERKNEMTQVITRTQE
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE3 KKLSFIEALIQQYQEQLDKSTKLVETAIQSLDEPGGATFLLTAKQLIKSIVEASKGCQLG
.:: ..:::..:...:.. .::::..:: .::: :.:: .:: :.:.: ::::. :.
NP_149 EKLEHVRALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTLLKKISEASKAFQME
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE3 KTEQGFENMDFFTLDLEHIADALRAIDFGTDEEEEEFIEEEDQEEEESTEGKEEGHQ
: :.:.:::. ::..:.. .: ::: . :.::.::::. ::..::
NP_149 KIEHGYENMNHFTVNLNREEKIIREIDF--------YREDEDEEEEEGGEGEKEGEGEVG
300 310 320 330 340 350
NP_149 GEAVEVEEVENVQTEFPGEDENPEKASELSQVELQAAPGALPVSSPEPPPALPPAADAPV
360 370 380 390 400 410
>>NP_908973 (OMIM: 606469) tripartite motif-containing p (548 aa)
initn: 843 init1: 820 opt: 1449 Z-score: 1127.3 bits: 217.7 E(85289): 4.7e-56
Smith-Waterman score: 1449; 60.4% identity (84.3% similar) in 351 aa overlap (1-351:5-345)
10 20 30 40 50
pF1KE3 MDYKSSLIQDGNPMENLEKQLICPICLEMFTKPVVILPCQHNLCRKCANDIFQAAN
..::: . .. . :.:::::::::::::::::::::::::::::::::.:::::.:
NP_908 MSASLNYKS-FSKEQQTMDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCASDIFQASN
10 20 30 40 50
60 70 80 90 100 110
pF1KE3 PYWTSRGSSVSMSGGRFRCPTCRHEVIMDRHGVYGLQRNLLVENIIDIYKQECSSRPLQK
:: .::... ::::::::.:::::..:::::::::::::::::::::::: :.:: .:
NP_908 PYLPTRGGTTMASGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQE-STRPEKK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE3 GSHPMCKEHEDEKINIYCLTCEVPTCSMCKVFGIHKACEVAPLQSVFQGQKTELNNCISM
...:::.:::.:.::::::.:::::::.::::: :: :.:::: ::: ::.::.. :..
NP_908 SDQPMCEEHEEERINIYCLNCEVPTCSLCKVFGAHKDCQVAPLTHVFQRQKSELSDGIAI
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE3 LVAGNDRVQTIITQLEDSRRVTKENSHQVKEELSQKFDTLYAILDEKKSELLQRITQEQE
::..::::: .:.::::. .. .: .. :.:: .::: ::.::.:.:.:. : ::. ::
NP_908 LVGSNDRVQGVISQLEDTCKTIEECCRKQKQELCEKFDYLYGILEERKNEMTQVITRTQE
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE3 KKLSFIEALIQQYQEQLDKSTKLVETAIQSLDEPGGATFLLTAKQLIKSIVEASKGCQLG
.:: ..:::..:...:.. .::::..:: .::: :.:: .:: :.:.: ::::. :.
NP_908 EKLEHVRALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTLLKKISEASKAFQME
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE3 KTEQGFENMDFFTLDLEHIADALRAIDFGTDEEEEEFIEEEDQEEEESTEGKEEGHQ
: :.:.:::. ::..:.. .: ::: . :.::.::::. ::..::
NP_908 KIEHGYENMNHFTVNLNREEKIIREIDF--------YREDEDEEEEEGGEGEKEGEGEVG
300 310 320 330 340 350
NP_908 GEAVEVEEVENVQTEFPGEDENPEKASELSQVELQAAPGALPVSSPEPPPALPPAADAPV
360 370 380 390 400 410
>>XP_011515915 (OMIM: 606469) PREDICTED: tripartite moti (548 aa)
initn: 843 init1: 820 opt: 1449 Z-score: 1127.3 bits: 217.7 E(85289): 4.7e-56
Smith-Waterman score: 1449; 60.4% identity (84.3% similar) in 351 aa overlap (1-351:5-345)
10 20 30 40 50
pF1KE3 MDYKSSLIQDGNPMENLEKQLICPICLEMFTKPVVILPCQHNLCRKCANDIFQAAN
..::: . .. . :.:::::::::::::::::::::::::::::::::.:::::.:
XP_011 MSASLNYKS-FSKEQQTMDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCASDIFQASN
10 20 30 40 50
60 70 80 90 100 110
pF1KE3 PYWTSRGSSVSMSGGRFRCPTCRHEVIMDRHGVYGLQRNLLVENIIDIYKQECSSRPLQK
:: .::... ::::::::.:::::..:::::::::::::::::::::::: :.:: .:
XP_011 PYLPTRGGTTMASGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQE-STRPEKK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE3 GSHPMCKEHEDEKINIYCLTCEVPTCSMCKVFGIHKACEVAPLQSVFQGQKTELNNCISM
...:::.:::.:.::::::.:::::::.::::: :: :.:::: ::: ::.::.. :..
XP_011 SDQPMCEEHEEERINIYCLNCEVPTCSLCKVFGAHKDCQVAPLTHVFQRQKSELSDGIAI
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE3 LVAGNDRVQTIITQLEDSRRVTKENSHQVKEELSQKFDTLYAILDEKKSELLQRITQEQE
::..::::: .:.::::. .. .: .. :.:: .::: ::.::.:.:.:. : ::. ::
XP_011 LVGSNDRVQGVISQLEDTCKTIEECCRKQKQELCEKFDYLYGILEERKNEMTQVITRTQE
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE3 KKLSFIEALIQQYQEQLDKSTKLVETAIQSLDEPGGATFLLTAKQLIKSIVEASKGCQLG
.:: ..:::..:...:.. .::::..:: .::: :.:: .:: :.:.: ::::. :.
XP_011 EKLEHVRALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTLLKKISEASKAFQME
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE3 KTEQGFENMDFFTLDLEHIADALRAIDFGTDEEEEEFIEEEDQEEEESTEGKEEGHQ
: :.:.:::. ::..:.. .: ::: . :.::.::::. ::..::
XP_011 KIEHGYENMNHFTVNLNREEKIIREIDF--------YREDEDEEEEEGGEGEKEGEGEVG
300 310 320 330 340 350
XP_011 GEAVEVEEVENVQTEFPGEDENPEKASELSQVELQAAPGALPVSSPEPPPALPPAADAPV
360 370 380 390 400 410
>>XP_011515916 (OMIM: 606469) PREDICTED: tripartite moti (548 aa)
initn: 843 init1: 820 opt: 1449 Z-score: 1127.3 bits: 217.7 E(85289): 4.7e-56
Smith-Waterman score: 1449; 60.4% identity (84.3% similar) in 351 aa overlap (1-351:5-345)
10 20 30 40 50
pF1KE3 MDYKSSLIQDGNPMENLEKQLICPICLEMFTKPVVILPCQHNLCRKCANDIFQAAN
..::: . .. . :.:::::::::::::::::::::::::::::::::.:::::.:
XP_011 MSASLNYKS-FSKEQQTMDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCASDIFQASN
10 20 30 40 50
60 70 80 90 100 110
pF1KE3 PYWTSRGSSVSMSGGRFRCPTCRHEVIMDRHGVYGLQRNLLVENIIDIYKQECSSRPLQK
:: .::... ::::::::.:::::..:::::::::::::::::::::::: :.:: .:
XP_011 PYLPTRGGTTMASGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQE-STRPEKK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE3 GSHPMCKEHEDEKINIYCLTCEVPTCSMCKVFGIHKACEVAPLQSVFQGQKTELNNCISM
...:::.:::.:.::::::.:::::::.::::: :: :.:::: ::: ::.::.. :..
XP_011 SDQPMCEEHEEERINIYCLNCEVPTCSLCKVFGAHKDCQVAPLTHVFQRQKSELSDGIAI
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE3 LVAGNDRVQTIITQLEDSRRVTKENSHQVKEELSQKFDTLYAILDEKKSELLQRITQEQE
::..::::: .:.::::. .. .: .. :.:: .::: ::.::.:.:.:. : ::. ::
XP_011 LVGSNDRVQGVISQLEDTCKTIEECCRKQKQELCEKFDYLYGILEERKNEMTQVITRTQE
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE3 KKLSFIEALIQQYQEQLDKSTKLVETAIQSLDEPGGATFLLTAKQLIKSIVEASKGCQLG
.:: ..:::..:...:.. .::::..:: .::: :.:: .:: :.:.: ::::. :.
XP_011 EKLEHVRALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTLLKKISEASKAFQME
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE3 KTEQGFENMDFFTLDLEHIADALRAIDFGTDEEEEEFIEEEDQEEEESTEGKEEGHQ
: :.:.:::. ::..:.. .: ::: . :.::.::::. ::..::
XP_011 KIEHGYENMNHFTVNLNREEKIIREIDF--------YREDEDEEEEEGGEGEKEGEGEVG
300 310 320 330 340 350
XP_011 GEAVEVEEVENVQTEFPGEDENPEKASELSQVELQAAPGALPVSSPEPPPALPPAADAPV
360 370 380 390 400 410
>>XP_005251373 (OMIM: 606469) PREDICTED: tripartite moti (547 aa)
initn: 853 init1: 830 opt: 1446 Z-score: 1125.0 bits: 217.3 E(85289): 6.3e-56
Smith-Waterman score: 1446; 60.7% identity (83.8% similar) in 351 aa overlap (1-351:5-350)
10 20 30 40 50
pF1KE3 MDYKSSLIQDGNPMENLEKQLICPICLEMFTKPVVILPCQHNLCRKCANDIFQAAN
..::: . .. . :.:::::::::::::::::::::::::::::::::.:::::.:
XP_005 MSASLNYKS-FSKEQQTMDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCASDIFQASN
10 20 30 40 50
60 70 80 90 100 110
pF1KE3 PYWTSRGSSVSMSGGRFRCPTCRHEVIMDRHGVYGLQRNLLVENIIDIYKQECSSRPLQK
:: .::... ::::::::.:::::..:::::::::::::::::::::::: :.:: .:
XP_005 PYLPTRGGTTMASGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQE-STRPEKK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE3 GSHPMCKEHEDEKINIYCLTCEVPTCSMCKVFGIHKACEVAPLQSVFQGQKTELNNCISM
...:::.:::.:.::::::.:::::::.::::: :: :.:::: ::: ::.::.. :..
XP_005 SDQPMCEEHEEERINIYCLNCEVPTCSLCKVFGAHKDCQVAPLTHVFQRQKSELSDGIAI
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE3 LVAGNDRVQTIITQLEDSRRVTKENSHQVKEELSQKFDTLYAILDEKKSELLQRITQEQE
::..::::: .:.::::. .. .: .. :.:: .::: ::.::.:.:.:. : ::. ::
XP_005 LVGSNDRVQGVISQLEDTCKTIEECCRKQKQELCEKFDYLYGILEERKNEMTQVITRTQE
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE3 KKLSFIEALIQQYQEQLDKSTKLVETAIQSLDEPGGATFLLTAKQLIKSIVEASKGCQLG
.:: ..:::..:...:.. .::::..:: .::: :.:: .:: :.:.: ::::. :.
XP_005 EKLEHVRALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTLLKKISEASKAFQME
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE3 KTEQGFENMDFFTLDLEHIADALRAIDFGTDEEEEEFIEEEDQEEEESTEGKEEGHQ
: :.:.:::. ::..:.. .: ::: ::.:: ::: : :. ::. :
XP_005 KIEHGYENMNHFTVNLNREEKIIREIDFYRDEDEE---EEEGGEGEKEGEGEVGGEAVEV
300 310 320 330 340 350
XP_005 EEVENVQTEFPGEDENPEKASELSQVELQAAPGALPVSSPEPPPALPPAADAPVTQGEVV
360 370 380 390 400 410
353 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 19:26:04 2016 done: Sun Nov 6 19:26:05 2016
Total Scan time: 8.750 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]