Result of FASTA (ccds) for
pFN21AE3140
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3140, 350 aa
1>>>pF1KE3140 350 - 350 aa - 350 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.2828+/-0.00073; mu= 10.1997+/- 0.045
mean_var=170.9125+/-33.854, 0's: 0 Z-trim(116.0): 69 B-trim: 0 in 0/55
Lambda= 0.098104
statistics sampled from 16462 (16535) to 16462 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.802), E-opt: 0.2 (0.508), width: 16
Scan time: 3.010
The best scores are: opt bits E(32554)
CCDS11060.1 RNF167 gene_id:26001|Hs108|chr17 ( 350) 2421 353.9 1.2e-97
CCDS82040.1 RNF167 gene_id:26001|Hs108|chr17 ( 315) 2186 320.6 1.1e-87
CCDS3146.1 RNF13 gene_id:11342|Hs108|chr3 ( 381) 1104 167.5 1.6e-41
CCDS42475.1 ZNRF4 gene_id:148066|Hs108|chr19 ( 429) 728 114.4 1.8e-25
>>CCDS11060.1 RNF167 gene_id:26001|Hs108|chr17 (350 aa)
initn: 2421 init1: 2421 opt: 2421 Z-score: 1866.7 bits: 353.9 E(32554): 1.2e-97
Smith-Waterman score: 2421; 100.0% identity (100.0% similar) in 350 aa overlap (1-350:1-350)
10 20 30 40 50 60
pF1KE3 MHPAAFPLPVVVAAVLWGAAPTRGLIRATSDHNASMDFADLPALFGATLSQEGLQGFLVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 MHPAAFPLPVVVAAVLWGAAPTRGLIRATSDHNASMDFADLPALFGATLSQEGLQGFLVE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 AHPDNACSPIAPPPPAPVNGSVFIALLRRFDCNFDLKVLNAQKAGYGAAVVHNVNSNELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 AHPDNACSPIAPPPPAPVNGSVFIALLRRFDCNFDLKVLNAQKAGYGAAVVHNVNSNELL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 NMVWNSEEIQQQIWIPSVFIGERSSEYLRALFVYEKGARVLLVPDNTFPLGYYLIPFTGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 NMVWNSEEIQQQIWIPSVFIGERSSEYLRALFVYEKGARVLLVPDNTFPLGYYLIPFTGI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 VGLLVLAMGAVMIARCIQHRKRLQRNRLTKEQLKQIPTHDYQKGDQYDVCAICLDEYEDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 VGLLVLAMGAVMIARCIQHRKRLQRNRLTKEQLKQIPTHDYQKGDQYDVCAICLDEYEDG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 DKLRVLPCAHAYHSRCVDPWLTQTRKTCPICKQPVHRGPGDEDQEEETQGQEEGDEGEPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 DKLRVLPCAHAYHSRCVDPWLTQTRKTCPICKQPVHRGPGDEDQEEETQGQEEGDEGEPR
250 260 270 280 290 300
310 320 330 340 350
pF1KE3 DHPASERTPLLGSSPTLPTSFGSLAPAPLVFPGPSTDPPLSPPSSPVILV
::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 DHPASERTPLLGSSPTLPTSFGSLAPAPLVFPGPSTDPPLSPPSSPVILV
310 320 330 340 350
>>CCDS82040.1 RNF167 gene_id:26001|Hs108|chr17 (315 aa)
initn: 2186 init1: 2186 opt: 2186 Z-score: 1687.5 bits: 320.6 E(32554): 1.1e-87
Smith-Waterman score: 2186; 100.0% identity (100.0% similar) in 315 aa overlap (36-350:1-315)
10 20 30 40 50 60
pF1KE3 FPLPVVVAAVLWGAAPTRGLIRATSDHNASMDFADLPALFGATLSQEGLQGFLVEAHPDN
::::::::::::::::::::::::::::::
CCDS82 MDFADLPALFGATLSQEGLQGFLVEAHPDN
10 20 30
70 80 90 100 110 120
pF1KE3 ACSPIAPPPPAPVNGSVFIALLRRFDCNFDLKVLNAQKAGYGAAVVHNVNSNELLNMVWN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 ACSPIAPPPPAPVNGSVFIALLRRFDCNFDLKVLNAQKAGYGAAVVHNVNSNELLNMVWN
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE3 SEEIQQQIWIPSVFIGERSSEYLRALFVYEKGARVLLVPDNTFPLGYYLIPFTGIVGLLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 SEEIQQQIWIPSVFIGERSSEYLRALFVYEKGARVLLVPDNTFPLGYYLIPFTGIVGLLV
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE3 LAMGAVMIARCIQHRKRLQRNRLTKEQLKQIPTHDYQKGDQYDVCAICLDEYEDGDKLRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 LAMGAVMIARCIQHRKRLQRNRLTKEQLKQIPTHDYQKGDQYDVCAICLDEYEDGDKLRV
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE3 LPCAHAYHSRCVDPWLTQTRKTCPICKQPVHRGPGDEDQEEETQGQEEGDEGEPRDHPAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 LPCAHAYHSRCVDPWLTQTRKTCPICKQPVHRGPGDEDQEEETQGQEEGDEGEPRDHPAS
220 230 240 250 260 270
310 320 330 340 350
pF1KE3 ERTPLLGSSPTLPTSFGSLAPAPLVFPGPSTDPPLSPPSSPVILV
:::::::::::::::::::::::::::::::::::::::::::::
CCDS82 ERTPLLGSSPTLPTSFGSLAPAPLVFPGPSTDPPLSPPSSPVILV
280 290 300 310
>>CCDS3146.1 RNF13 gene_id:11342|Hs108|chr3 (381 aa)
initn: 1106 init1: 1085 opt: 1104 Z-score: 858.8 bits: 167.5 E(32554): 1.6e-41
Smith-Waterman score: 1112; 53.3% identity (79.7% similar) in 306 aa overlap (21-325:31-327)
10 20 30 40 50
pF1KE3 MHPAAFPLPVVVAAVLWGAAPTRGLIRATSDHNASMDFADLPALFGATLS
:... : : . .:::. : :::: :: :
CCDS31 MLLSIGMLMLSATQVYTILTVQLFAFLNLLPVEADILAYNFENASQTFDDLPARFGYRLP
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 QEGLQGFLVEAHPDNACSPIAPPPPAPVNGSVFIALLRRFDCNFDLKVLNAQKAGYGAAV
:::.:::....:.::: ::.::: ....::.:.::.:::::.::::::.::: ::.
CCDS31 AEGLKGFLINSKPENACEPIVPPPVKDNSSGTFIVLIRRLDCNFDIKVLNAQRAGYKAAI
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE3 VHNVNSNELLNMVWNSEEIQQQIWIPSVFIGERSSEYLRALFVYEKGARVLLVPDNTFPL
::::.:..:..: :. :. ..: :::::::: :.. :. :.::::....:::. ..::
CCDS31 VHNVDSDDLISMGSNDIEVLKKIDIPSVFIGESSANSLKDEFTYEKGGHLILVPEFSLPL
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE3 GYYLIPFTGIVGLLVLAMGAVMIARCIQHRKRLQRNRLTKEQLKQIPTHDYQKGDQYDVC
:::::: :::. .. . ::.. .: :.: .:::: :.:::..:.: ..:::.::::
CCDS31 EYYLIPFLIIVGICLILIVIFMITKFVQDRHRARRNRLRKDQLKKLPVHKFKKGDEYDVC
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE3 AICLDEYEDGDKLRVLPCAHAYHSRCVDPWLTQTRKTCPICKQPVHRGPGDEDQEEETQG
::::::::::::::.:::.:::: .:::::::.:.::::.::: : . :: :.. ...
CCDS31 AICLDEYEDGDKLRILPCSHAYHCKCVDPWLTKTKKTCPVCKQKVVPSQGDSDSDTDSS-
250 260 270 280 290
300 310 320 330 340
pF1KE3 QEEGDEGEPRDHPASERTPLLGSSPTLPT-SFGSLAPAPLVFPGPSTDPPLSPPSSPVIL
:::.. ..:.:::: .. . :::.:.
CCDS31 QEENE--------VTEHTPLLRPLASVSAQSFGALSESRSHQNMTESSDYEEDDNEDTDS
300 310 320 330 340 350
350
pF1KE3 V
CCDS31 SDAENEINEHDVVVQLQPNGERDYNIANTV
360 370 380
>>CCDS42475.1 ZNRF4 gene_id:148066|Hs108|chr19 (429 aa)
initn: 730 init1: 283 opt: 728 Z-score: 570.6 bits: 114.4 E(32554): 1.8e-25
Smith-Waterman score: 778; 39.4% identity (67.5% similar) in 348 aa overlap (21-342:95-427)
10 20 30 40
pF1KE3 MHPAAFPLPVVVAAVLWGAAPTRGLIRAT-SDHNASMDFADLPALFGATL
:.....::. :...:.::::::::::. :
CCDS42 TAKRVTMGWPRPGRALVAVKALLVLSLLQVPAQAVVRAVLEDNSSSVDFADLPALFGVPL
70 80 90 100 110 120
50 60 70 80 90 100
pF1KE3 SQEGLQGFLVEAHPDNACSPIAPPPPAPVNGSV-FIALLRRFDCNFDLKVLNAQKAGYGA
. ::..:.:.:..: ::: :: : . : :. :.:.::.::.:::::::::.::. :
CCDS42 APEGIRGYLMEVKPANACHPIEAPRLG--NRSLGAIVLIRRYDCTFDLKVLNAQRAGFEA
130 140 150 160 170 180
110 120 130 140 150 160
pF1KE3 AVVHNVNSNELLNMVWNSEEIQQQIWIPSVFIGERSSEYLRALFVYEKGARVLLVPDNT-
:.::::.:..:..:. :... :: :::::..: .:. ::... .:.:..::.::.
CCDS42 AIVHNVHSDDLVSMTHVYEDLRGQIAIPSVFVSEAASQDLRVILGCNKSAHALLLPDDPP
190 200 210 220 230 240
170 180 190 200 210
pF1KE3 -FPLGYY-LIPFTGIVG-LLVLAMGAVMIAR--------CIQHRKRLQRNRLTKEQLKQI
:: . .. . ..: :.:...: .. : .::. .. . : :.. .
CCDS42 CHDLGCHPVLTVSWVLGCTLALVVSAFFVLNHLWLWAQACCSHRRPVKTSTCQKAQVRTF
250 260 270 280 290 300
220 230 240 250 260 270
pF1KE3 PTHDYQKGDQYDVCAICLDEYEDGDKLRVLPCAHAYHSRCVDPWLTQT-RKTCPICKQPV
:. :.:::::::::.::.:..:::.:.:: .:.:::..:. :..::.::: :
CCDS42 TWHN-------DLCAICLDEYEEGDQLKILPCSHTYHCKCIDPWFSQAPRRSCPVCKQSV
310 320 330 340 350
280 290 300 310 320
pF1KE3 HRGPGDEDQ-EEETQGQEEGDEGEPRDHPA---------SERTPLLG-SSPTLPTSFGSL
. ::. . : . .. : . : .: :.: ::: .:: : ::
CCDS42 ---AATEDSFDSTTYSFRDEDPSLPGHRPPIWAIQVQLRSRRLELLGRASPHCHCSTTSL
360 370 380 390 400 410
330 340 350
pF1KE3 APAPLVFPGPSTDPPLSPPSSPVILV
. :. :: .:
CCDS42 EAE---YTTVSSAPPEAPGQ
420
350 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 13:57:29 2016 done: Sun Nov 6 13:57:29 2016
Total Scan time: 3.010 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]