Result of FASTA (omim) for
pFN21AE3132
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3132, 336 aa
1>>>pF1KE3132 336 - 336 aa - 336 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.4525+/-0.000369; mu= 7.5117+/- 0.023
mean_var=140.4606+/-27.097, 0's: 0 Z-trim(117.4): 40 B-trim: 0 in 0/55
Lambda= 0.108217
statistics sampled from 29370 (29407) to 29370 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.698), E-opt: 0.2 (0.345), width: 16
Scan time: 8.430
The best scores are: opt bits E(85289)
NP_001135888 (OMIM: 260600,603605) aminoacyl tRNA ( 336) 2161 348.6 1.1e-95
NP_001135887 (OMIM: 260600,603605) aminoacyl tRNA ( 312) 2007 324.5 1.8e-88
NP_004748 (OMIM: 260600,603605) aminoacyl tRNA syn ( 312) 2007 324.5 1.8e-88
XP_016864325 (OMIM: 260600,603605) PREDICTED: amin ( 312) 2007 324.5 1.8e-88
XP_016864324 (OMIM: 260600,603605) PREDICTED: amin ( 312) 2007 324.5 1.8e-88
XP_011540649 (OMIM: 603623,608323) PREDICTED: tyro ( 318) 597 104.4 3.4e-22
XP_016858140 (OMIM: 603623,608323) PREDICTED: tyro ( 318) 597 104.4 3.4e-22
XP_011540650 (OMIM: 603623,608323) PREDICTED: tyro ( 318) 597 104.4 3.4e-22
NP_003671 (OMIM: 603623,608323) tyrosine--tRNA lig ( 528) 597 104.5 5.1e-22
>>NP_001135888 (OMIM: 260600,603605) aminoacyl tRNA synt (336 aa)
initn: 2161 init1: 2161 opt: 2161 Z-score: 1838.8 bits: 348.6 E(85289): 1.1e-95
Smith-Waterman score: 2161; 100.0% identity (100.0% similar) in 336 aa overlap (1-336:1-336)
10 20 30 40 50 60
pF1KE3 MLPAVAVSEPVVLRFMIFCRLLAKMANNDAVLKRLEQKGAEADQIIEYLKQQVSLLKEKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLPAVAVSEPVVLRFMIFCRLLAKMANNDAVLKRLEQKGAEADQIIEYLKQQVSLLKEKA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 ILQATLREEKKLRVENAKLKKEIEELKQELIQAEIQNGVKQIPFPSGTPLHANSMVSENV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILQATLREEKKLRVENAKLKKEIEELKQELIQAEIQNGVKQIPFPSGTPLHANSMVSENV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 IQSTAVTTVSSGTKEQIKGGTGDEKKAKEKIEKKGEKKEKKQQSIAGSADSKPIDVSRLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IQSTAVTTVSSGTKEQIKGGTGDEKKAKEKIEKKGEKKEKKQQSIAGSADSKPIDVSRLD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 LRIGCIITARKHPDADSLYVEEVDVGEIAPRTVVSGLVNHVPLEQMQNRMVILLCNLKPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRIGCIITARKHPDADSLYVEEVDVGEIAPRTVVSGLVNHVPLEQMQNRMVILLCNLKPA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 KMRGVLSQAMVMCASSPEKIEILAPPNGSVPGDRITFDAFPGEPDKELNPKKKIWEQIQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KMRGVLSQAMVMCASSPEKIEILAPPNGSVPGDRITFDAFPGEPDKELNPKKKIWEQIQP
250 260 270 280 290 300
310 320 330
pF1KE3 DLHTNDECVATYKGVPFEVKGKGVCRAQTMSNSGIK
::::::::::::::::::::::::::::::::::::
NP_001 DLHTNDECVATYKGVPFEVKGKGVCRAQTMSNSGIK
310 320 330
>>NP_001135887 (OMIM: 260600,603605) aminoacyl tRNA synt (312 aa)
initn: 2007 init1: 2007 opt: 2007 Z-score: 1709.3 bits: 324.5 E(85289): 1.8e-88
Smith-Waterman score: 2007; 100.0% identity (100.0% similar) in 312 aa overlap (25-336:1-312)
10 20 30 40 50 60
pF1KE3 MLPAVAVSEPVVLRFMIFCRLLAKMANNDAVLKRLEQKGAEADQIIEYLKQQVSLLKEKA
::::::::::::::::::::::::::::::::::::
NP_001 MANNDAVLKRLEQKGAEADQIIEYLKQQVSLLKEKA
10 20 30
70 80 90 100 110 120
pF1KE3 ILQATLREEKKLRVENAKLKKEIEELKQELIQAEIQNGVKQIPFPSGTPLHANSMVSENV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILQATLREEKKLRVENAKLKKEIEELKQELIQAEIQNGVKQIPFPSGTPLHANSMVSENV
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE3 IQSTAVTTVSSGTKEQIKGGTGDEKKAKEKIEKKGEKKEKKQQSIAGSADSKPIDVSRLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IQSTAVTTVSSGTKEQIKGGTGDEKKAKEKIEKKGEKKEKKQQSIAGSADSKPIDVSRLD
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE3 LRIGCIITARKHPDADSLYVEEVDVGEIAPRTVVSGLVNHVPLEQMQNRMVILLCNLKPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRIGCIITARKHPDADSLYVEEVDVGEIAPRTVVSGLVNHVPLEQMQNRMVILLCNLKPA
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE3 KMRGVLSQAMVMCASSPEKIEILAPPNGSVPGDRITFDAFPGEPDKELNPKKKIWEQIQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KMRGVLSQAMVMCASSPEKIEILAPPNGSVPGDRITFDAFPGEPDKELNPKKKIWEQIQP
220 230 240 250 260 270
310 320 330
pF1KE3 DLHTNDECVATYKGVPFEVKGKGVCRAQTMSNSGIK
::::::::::::::::::::::::::::::::::::
NP_001 DLHTNDECVATYKGVPFEVKGKGVCRAQTMSNSGIK
280 290 300 310
>>NP_004748 (OMIM: 260600,603605) aminoacyl tRNA synthas (312 aa)
initn: 2007 init1: 2007 opt: 2007 Z-score: 1709.3 bits: 324.5 E(85289): 1.8e-88
Smith-Waterman score: 2007; 100.0% identity (100.0% similar) in 312 aa overlap (25-336:1-312)
10 20 30 40 50 60
pF1KE3 MLPAVAVSEPVVLRFMIFCRLLAKMANNDAVLKRLEQKGAEADQIIEYLKQQVSLLKEKA
::::::::::::::::::::::::::::::::::::
NP_004 MANNDAVLKRLEQKGAEADQIIEYLKQQVSLLKEKA
10 20 30
70 80 90 100 110 120
pF1KE3 ILQATLREEKKLRVENAKLKKEIEELKQELIQAEIQNGVKQIPFPSGTPLHANSMVSENV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ILQATLREEKKLRVENAKLKKEIEELKQELIQAEIQNGVKQIPFPSGTPLHANSMVSENV
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE3 IQSTAVTTVSSGTKEQIKGGTGDEKKAKEKIEKKGEKKEKKQQSIAGSADSKPIDVSRLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 IQSTAVTTVSSGTKEQIKGGTGDEKKAKEKIEKKGEKKEKKQQSIAGSADSKPIDVSRLD
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE3 LRIGCIITARKHPDADSLYVEEVDVGEIAPRTVVSGLVNHVPLEQMQNRMVILLCNLKPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LRIGCIITARKHPDADSLYVEEVDVGEIAPRTVVSGLVNHVPLEQMQNRMVILLCNLKPA
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE3 KMRGVLSQAMVMCASSPEKIEILAPPNGSVPGDRITFDAFPGEPDKELNPKKKIWEQIQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KMRGVLSQAMVMCASSPEKIEILAPPNGSVPGDRITFDAFPGEPDKELNPKKKIWEQIQP
220 230 240 250 260 270
310 320 330
pF1KE3 DLHTNDECVATYKGVPFEVKGKGVCRAQTMSNSGIK
::::::::::::::::::::::::::::::::::::
NP_004 DLHTNDECVATYKGVPFEVKGKGVCRAQTMSNSGIK
280 290 300 310
>>XP_016864325 (OMIM: 260600,603605) PREDICTED: aminoacy (312 aa)
initn: 2007 init1: 2007 opt: 2007 Z-score: 1709.3 bits: 324.5 E(85289): 1.8e-88
Smith-Waterman score: 2007; 100.0% identity (100.0% similar) in 312 aa overlap (25-336:1-312)
10 20 30 40 50 60
pF1KE3 MLPAVAVSEPVVLRFMIFCRLLAKMANNDAVLKRLEQKGAEADQIIEYLKQQVSLLKEKA
::::::::::::::::::::::::::::::::::::
XP_016 MANNDAVLKRLEQKGAEADQIIEYLKQQVSLLKEKA
10 20 30
70 80 90 100 110 120
pF1KE3 ILQATLREEKKLRVENAKLKKEIEELKQELIQAEIQNGVKQIPFPSGTPLHANSMVSENV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILQATLREEKKLRVENAKLKKEIEELKQELIQAEIQNGVKQIPFPSGTPLHANSMVSENV
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE3 IQSTAVTTVSSGTKEQIKGGTGDEKKAKEKIEKKGEKKEKKQQSIAGSADSKPIDVSRLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IQSTAVTTVSSGTKEQIKGGTGDEKKAKEKIEKKGEKKEKKQQSIAGSADSKPIDVSRLD
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE3 LRIGCIITARKHPDADSLYVEEVDVGEIAPRTVVSGLVNHVPLEQMQNRMVILLCNLKPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRIGCIITARKHPDADSLYVEEVDVGEIAPRTVVSGLVNHVPLEQMQNRMVILLCNLKPA
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE3 KMRGVLSQAMVMCASSPEKIEILAPPNGSVPGDRITFDAFPGEPDKELNPKKKIWEQIQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KMRGVLSQAMVMCASSPEKIEILAPPNGSVPGDRITFDAFPGEPDKELNPKKKIWEQIQP
220 230 240 250 260 270
310 320 330
pF1KE3 DLHTNDECVATYKGVPFEVKGKGVCRAQTMSNSGIK
::::::::::::::::::::::::::::::::::::
XP_016 DLHTNDECVATYKGVPFEVKGKGVCRAQTMSNSGIK
280 290 300 310
>>XP_016864324 (OMIM: 260600,603605) PREDICTED: aminoacy (312 aa)
initn: 2007 init1: 2007 opt: 2007 Z-score: 1709.3 bits: 324.5 E(85289): 1.8e-88
Smith-Waterman score: 2007; 100.0% identity (100.0% similar) in 312 aa overlap (25-336:1-312)
10 20 30 40 50 60
pF1KE3 MLPAVAVSEPVVLRFMIFCRLLAKMANNDAVLKRLEQKGAEADQIIEYLKQQVSLLKEKA
::::::::::::::::::::::::::::::::::::
XP_016 MANNDAVLKRLEQKGAEADQIIEYLKQQVSLLKEKA
10 20 30
70 80 90 100 110 120
pF1KE3 ILQATLREEKKLRVENAKLKKEIEELKQELIQAEIQNGVKQIPFPSGTPLHANSMVSENV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILQATLREEKKLRVENAKLKKEIEELKQELIQAEIQNGVKQIPFPSGTPLHANSMVSENV
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE3 IQSTAVTTVSSGTKEQIKGGTGDEKKAKEKIEKKGEKKEKKQQSIAGSADSKPIDVSRLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IQSTAVTTVSSGTKEQIKGGTGDEKKAKEKIEKKGEKKEKKQQSIAGSADSKPIDVSRLD
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE3 LRIGCIITARKHPDADSLYVEEVDVGEIAPRTVVSGLVNHVPLEQMQNRMVILLCNLKPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRIGCIITARKHPDADSLYVEEVDVGEIAPRTVVSGLVNHVPLEQMQNRMVILLCNLKPA
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE3 KMRGVLSQAMVMCASSPEKIEILAPPNGSVPGDRITFDAFPGEPDKELNPKKKIWEQIQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KMRGVLSQAMVMCASSPEKIEILAPPNGSVPGDRITFDAFPGEPDKELNPKKKIWEQIQP
220 230 240 250 260 270
310 320 330
pF1KE3 DLHTNDECVATYKGVPFEVKGKGVCRAQTMSNSGIK
::::::::::::::::::::::::::::::::::::
XP_016 DLHTNDECVATYKGVPFEVKGKGVCRAQTMSNSGIK
280 290 300 310
>>XP_011540649 (OMIM: 603623,608323) PREDICTED: tyrosine (318 aa)
initn: 564 init1: 391 opt: 597 Z-score: 519.5 bits: 104.4 E(85289): 3.4e-22
Smith-Waterman score: 597; 48.7% identity (76.4% similar) in 195 aa overlap (147-332:122-316)
120 130 140 150 160 170
pF1KE3 SENVIQSTAVTTVSSGTKEQIKGGTGDEKKAKEKIEKKGEKKEKKQQSIA-GSA-DSKPI
: .:. . . .::. .: : : .:.:
XP_011 EVVHPGDLKNSVEVALNKLLDPIREKFNTPALKKLASAAYPDPSKQKPMAKGPAKNSEPE
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE3 DV--SRLDLRIGCIITARKHPDADSLYVEEVDVGEIAPRTVVSGLVNHVPLEQMQNRMVI
.: ::::.:.: :::..:::::::::::..:::: :::::::::. :: :..:.:.:.
XP_011 EVIPSRLDIRVGKIITVEKHPDADSLYVEKIDVGEAEPRTVVSGLVQFVPKEELQDRLVV
160 170 180 190 200 210
240 250 260 270 280
pF1KE3 LLCNLKPAKMRGVLSQAMVMCASSP---EKIEILAPPNGSVPGDRITFDAFP-GEPDKEL
.:::::: ::::: ::.:..::: ...: : :: ::.::... .. :.::.::
XP_011 VLCNLKPQKMRGVESQGMLLCASIEGINRQVEPLDPPAGSAPGEHVFVKGYEKGQPDEEL
220 230 240 250 260 270
290 300 310 320 330
pF1KE3 NPKKKIWEQIQPDLHTNDECVATYKGVPFEVK-GKGVCRAQTMSNSGIK
.::::..:..: :.. ..::.: .: . : .: :. :.. .:
XP_011 KPKKKVFEKLQADFKISEECIAQWKQTNFMTKLGSISCKSLKGGNIS
280 290 300 310
>>XP_016858140 (OMIM: 603623,608323) PREDICTED: tyrosine (318 aa)
initn: 564 init1: 391 opt: 597 Z-score: 519.5 bits: 104.4 E(85289): 3.4e-22
Smith-Waterman score: 597; 48.7% identity (76.4% similar) in 195 aa overlap (147-332:122-316)
120 130 140 150 160 170
pF1KE3 SENVIQSTAVTTVSSGTKEQIKGGTGDEKKAKEKIEKKGEKKEKKQQSIA-GSA-DSKPI
: .:. . . .::. .: : : .:.:
XP_016 EVVHPGDLKNSVEVALNKLLDPIREKFNTPALKKLASAAYPDPSKQKPMAKGPAKNSEPE
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE3 DV--SRLDLRIGCIITARKHPDADSLYVEEVDVGEIAPRTVVSGLVNHVPLEQMQNRMVI
.: ::::.:.: :::..:::::::::::..:::: :::::::::. :: :..:.:.:.
XP_016 EVIPSRLDIRVGKIITVEKHPDADSLYVEKIDVGEAEPRTVVSGLVQFVPKEELQDRLVV
160 170 180 190 200 210
240 250 260 270 280
pF1KE3 LLCNLKPAKMRGVLSQAMVMCASSP---EKIEILAPPNGSVPGDRITFDAFP-GEPDKEL
.:::::: ::::: ::.:..::: ...: : :: ::.::... .. :.::.::
XP_016 VLCNLKPQKMRGVESQGMLLCASIEGINRQVEPLDPPAGSAPGEHVFVKGYEKGQPDEEL
220 230 240 250 260 270
290 300 310 320 330
pF1KE3 NPKKKIWEQIQPDLHTNDECVATYKGVPFEVK-GKGVCRAQTMSNSGIK
.::::..:..: :.. ..::.: .: . : .: :. :.. .:
XP_016 KPKKKVFEKLQADFKISEECIAQWKQTNFMTKLGSISCKSLKGGNIS
280 290 300 310
>>XP_011540650 (OMIM: 603623,608323) PREDICTED: tyrosine (318 aa)
initn: 564 init1: 391 opt: 597 Z-score: 519.5 bits: 104.4 E(85289): 3.4e-22
Smith-Waterman score: 597; 48.7% identity (76.4% similar) in 195 aa overlap (147-332:122-316)
120 130 140 150 160 170
pF1KE3 SENVIQSTAVTTVSSGTKEQIKGGTGDEKKAKEKIEKKGEKKEKKQQSIA-GSA-DSKPI
: .:. . . .::. .: : : .:.:
XP_011 EVVHPGDLKNSVEVALNKLLDPIREKFNTPALKKLASAAYPDPSKQKPMAKGPAKNSEPE
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE3 DV--SRLDLRIGCIITARKHPDADSLYVEEVDVGEIAPRTVVSGLVNHVPLEQMQNRMVI
.: ::::.:.: :::..:::::::::::..:::: :::::::::. :: :..:.:.:.
XP_011 EVIPSRLDIRVGKIITVEKHPDADSLYVEKIDVGEAEPRTVVSGLVQFVPKEELQDRLVV
160 170 180 190 200 210
240 250 260 270 280
pF1KE3 LLCNLKPAKMRGVLSQAMVMCASSP---EKIEILAPPNGSVPGDRITFDAFP-GEPDKEL
.:::::: ::::: ::.:..::: ...: : :: ::.::... .. :.::.::
XP_011 VLCNLKPQKMRGVESQGMLLCASIEGINRQVEPLDPPAGSAPGEHVFVKGYEKGQPDEEL
220 230 240 250 260 270
290 300 310 320 330
pF1KE3 NPKKKIWEQIQPDLHTNDECVATYKGVPFEVK-GKGVCRAQTMSNSGIK
.::::..:..: :.. ..::.: .: . : .: :. :.. .:
XP_011 KPKKKVFEKLQADFKISEECIAQWKQTNFMTKLGSISCKSLKGGNIS
280 290 300 310
>>NP_003671 (OMIM: 603623,608323) tyrosine--tRNA ligase, (528 aa)
initn: 564 init1: 391 opt: 597 Z-score: 516.3 bits: 104.5 E(85289): 5.1e-22
Smith-Waterman score: 597; 48.7% identity (76.4% similar) in 195 aa overlap (147-332:332-526)
120 130 140 150 160 170
pF1KE3 SENVIQSTAVTTVSSGTKEQIKGGTGDEKKAKEKIEKKGEKKEKKQQSIA-GSA-DSKPI
: .:. . . .::. .: : : .:.:
NP_003 EVVHPGDLKNSVEVALNKLLDPIREKFNTPALKKLASAAYPDPSKQKPMAKGPAKNSEPE
310 320 330 340 350 360
180 190 200 210 220 230
pF1KE3 DV--SRLDLRIGCIITARKHPDADSLYVEEVDVGEIAPRTVVSGLVNHVPLEQMQNRMVI
.: ::::.:.: :::..:::::::::::..:::: :::::::::. :: :..:.:.:.
NP_003 EVIPSRLDIRVGKIITVEKHPDADSLYVEKIDVGEAEPRTVVSGLVQFVPKEELQDRLVV
370 380 390 400 410 420
240 250 260 270 280
pF1KE3 LLCNLKPAKMRGVLSQAMVMCASSP---EKIEILAPPNGSVPGDRITFDAFP-GEPDKEL
.:::::: ::::: ::.:..::: ...: : :: ::.::... .. :.::.::
NP_003 VLCNLKPQKMRGVESQGMLLCASIEGINRQVEPLDPPAGSAPGEHVFVKGYEKGQPDEEL
430 440 450 460 470 480
290 300 310 320 330
pF1KE3 NPKKKIWEQIQPDLHTNDECVATYKGVPFEVK-GKGVCRAQTMSNSGIK
.::::..:..: :.. ..::.: .: . : .: :. :.. .:
NP_003 KPKKKVFEKLQADFKISEECIAQWKQTNFMTKLGSISCKSLKGGNIS
490 500 510 520
336 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 17:19:55 2016 done: Sun Nov 6 17:19:56 2016
Total Scan time: 8.430 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]