FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE3130, 323 aa
  1>>>pF1KE3130 323 - 323 aa - 323 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.8327+/-0.000445; mu= 0.8679+/- 0.028
 mean_var=227.9569+/-45.984, 0's: 0 Z-trim(117.3): 28  B-trim: 416 in 1/55
 Lambda= 0.084947
 statistics sampled from 29073 (29098) to 29073 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.686), E-opt: 0.2 (0.341), width:  16
 Scan time:  8.480

The best scores are:                                      opt bits E(85289)
NP_057107 (OMIM: 612021) OTU domain-containing pro ( 323) 2081 267.7 2.3e-71
XP_011515431 (OMIM: 612021) PREDICTED: OTU domain- ( 192) 1228 163.0 4.5e-40
NP_001273674 (OMIM: 612021) OTU domain-containing  ( 192) 1228 163.0 4.5e-40
NP_997203 (OMIM: 300714) OTU domain-containing pro ( 288) 1057 142.2 1.2e-33


>>NP_057107 (OMIM: 612021) OTU domain-containing protein  (323 aa)
 initn: 2081 init1: 2081 opt: 2081  Z-score: 1402.3  bits: 267.7 E(85289): 2.3e-71
Smith-Waterman score: 2081; 100.0% identity (100.0% similar) in 323 aa overlap (1-323:1-323)

               10        20        30        40        50        60
pF1KE3 MEPRVRVEGWKVPTSRCRFLLARVLGYLVVMEAVLTEELDEEEQLLRRHRKEKKELQAKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MEPRVRVEGWKVPTSRCRFLLARVLGYLVVMEAVLTEELDEEEQLLRRHRKEKKELQAKI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE3 QGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHREELEQLKLTTKENKIDSVAVNISNLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 QGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHREELEQLKLTTKENKIDSVAVNISNLV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE3 LENQPPRISKAQKRREKKAALEKEREERIAEAEIENLTGARHMESEKLAQILAARQLEIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 LENQPPRISKAQKRREKKAALEKEREERIAEAEIENLTGARHMESEKLAQILAARQLEIK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE3 QIPSDGHCMYKAIEDQLKEKDCALTVVALRSQTAEYMQSHVEDFLPFLTNPNTGDMYTPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 QIPSDGHCMYKAIEDQLKEKDCALTVVALRSQTAEYMQSHVEDFLPFLTNPNTGDMYTPE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE3 EFQKYCEDIVNTAAWGGQLELRALSHILQTPIEIIQADSPPIIVGEEYSKKPLILVYMRH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 EFQKYCEDIVNTAAWGGQLELRALSHILQTPIEIIQADSPPIIVGEEYSKKPLILVYMRH
              250       260       270       280       290       300

              310       320   
pF1KE3 AYGLGEHYNSVTRLVNIVTENCS
       :::::::::::::::::::::::
NP_057 AYGLGEHYNSVTRLVNIVTENCS
              310       320   

>>XP_011515431 (OMIM: 612021) PREDICTED: OTU domain-cont  (192 aa)
 initn: 1228 init1: 1228 opt: 1228  Z-score: 840.4  bits: 163.0 E(85289): 4.5e-40
Smith-Waterman score: 1228; 99.5% identity (100.0% similar) in 189 aa overlap (135-323:4-192)

          110       120       130       140       150       160    
pF1KE3 KENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIAEAEIENLTGARHME
                                     .:::::::::::::::::::::::::::::
XP_011                            MISKEKKAALEKEREERIAEAEIENLTGARHME
                                          10        20        30   

          170       180       190       200       210       220    
pF1KE3 SEKLAQILAARQLEIKQIPSDGHCMYKAIEDQLKEKDCALTVVALRSQTAEYMQSHVEDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEKLAQILAARQLEIKQIPSDGHCMYKAIEDQLKEKDCALTVVALRSQTAEYMQSHVEDF
            40        50        60        70        80        90   

          230       240       250       260       270       280    
pF1KE3 LPFLTNPNTGDMYTPEEFQKYCEDIVNTAAWGGQLELRALSHILQTPIEIIQADSPPIIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPFLTNPNTGDMYTPEEFQKYCEDIVNTAAWGGQLELRALSHILQTPIEIIQADSPPIIV
           100       110       120       130       140       150   

          290       300       310       320   
pF1KE3 GEEYSKKPLILVYMRHAYGLGEHYNSVTRLVNIVTENCS
       :::::::::::::::::::::::::::::::::::::::
XP_011 GEEYSKKPLILVYMRHAYGLGEHYNSVTRLVNIVTENCS
           160       170       180       190  

>>NP_001273674 (OMIM: 612021) OTU domain-containing prot  (192 aa)
 initn: 1228 init1: 1228 opt: 1228  Z-score: 840.4  bits: 163.0 E(85289): 4.5e-40
Smith-Waterman score: 1228; 99.5% identity (100.0% similar) in 189 aa overlap (135-323:4-192)

          110       120       130       140       150       160    
pF1KE3 KENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIAEAEIENLTGARHME
                                     .:::::::::::::::::::::::::::::
NP_001                            MISKEKKAALEKEREERIAEAEIENLTGARHME
                                          10        20        30   

          170       180       190       200       210       220    
pF1KE3 SEKLAQILAARQLEIKQIPSDGHCMYKAIEDQLKEKDCALTVVALRSQTAEYMQSHVEDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEKLAQILAARQLEIKQIPSDGHCMYKAIEDQLKEKDCALTVVALRSQTAEYMQSHVEDF
            40        50        60        70        80        90   

          230       240       250       260       270       280    
pF1KE3 LPFLTNPNTGDMYTPEEFQKYCEDIVNTAAWGGQLELRALSHILQTPIEIIQADSPPIIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPFLTNPNTGDMYTPEEFQKYCEDIVNTAAWGGQLELRALSHILQTPIEIIQADSPPIIV
           100       110       120       130       140       150   

          290       300       310       320   
pF1KE3 GEEYSKKPLILVYMRHAYGLGEHYNSVTRLVNIVTENCS
       :::::::::::::::::::::::::::::::::::::::
NP_001 GEEYSKKPLILVYMRHAYGLGEHYNSVTRLVNIVTENCS
           160       170       180       190  

>>NP_997203 (OMIM: 300714) OTU domain-containing protein  (288 aa)
 initn: 1056 init1: 507 opt: 1057  Z-score: 724.8  bits: 142.2 E(85289): 1.2e-33
Smith-Waterman score: 1057; 56.7% identity (85.5% similar) in 275 aa overlap (41-314:7-275)

               20        30        40        50        60        70
pF1KE3 KVPTSRCRFLLARVLGYLVVMEAVLTEELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKN
                                     :....::::..:..::::.:...::.:::.
NP_997                         MDDPKSEQQRILRRHQRERQELQAQIRSLKNSVPKT
                                       10        20        30      

               80        90       100       110       120       130
pF1KE3 DKKRRKQLTEDVAKLEKEMEQKHREELEQLKLTTKENKIDSVAVNISNLVLENQPPRISK
       :: .:::: .:::..: :: ::::.:::...    ...:.::. ..... :::.::: ::
NP_997 DKTKRKQLLQDVARMEAEMAQKHRQELEKFQ---DDSSIESVVEDLAKMNLENRPPRSSK
         40        50        60           70        80        90   

              140       150        160       170       180         
pF1KE3 AQKRREKKAALEKEREERIAEAEI-ENLTGARHMESEKLAQILAARQLEIKQIPSDGHCM
       :...::.  . :.::.: : .::. :.:.: .. : :::: ::.:: ::.: ::.:::::
NP_997 AHRKRERMESEERERQESIFQAEMSEHLAGFKREEEEKLAAILGARGLEMKAIPADGHCM
           100       110       120       130       140       150   

     190       200       210       220       230       240         
pF1KE3 YKAIEDQLKEKDCALTVVALRSQTAEYMQSHVEDFLPFLTNPNTGDMYTPEEFQKYCEDI
       :.::.:::     ...:  :: .:: ::..::..::::..::.:.: .  ..:. ::..:
NP_997 YRAIQDQLV---FSVSVEMLRCRTASYMKKHVDEFLPFFSNPETSDSFGYDDFMIYCDNI
           160          170       180       190       200       210

     250       260       270       280       290       300         
pF1KE3 VNTAAWGGQLELRALSHILQTPIEIIQADSPPIIVGEEYSKKPLILVYMRHAYGLGEHYN
       : :.:::::::::::::.:.::::.:::::: .:.:::: :::.::::.:.::.::::::
NP_997 VRTTAWGGQLELRALSHVLKTPIEVIQADSPTLIIGEEYVKKPIILVYLRYAYSLGEHYN
              220       230       240       250       260       270

     310       320       
pF1KE3 SVTRLVNIVTENCS    
       ::: :             
NP_997 SVTPLEAGAAGGVLPRLL
              280        




323 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sun Nov  6 16:05:43 2016 done: Sun Nov  6 16:05:44 2016
 Total Scan time:  8.480 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]