Result of FASTA (ccds) for
pFN21AE3125
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3125, 316 aa
1>>>pF1KE3125 316 - 316 aa - 316 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.2431+/-0.000852; mu= 11.5726+/- 0.051
mean_var=83.7579+/-16.853, 0's: 0 Z-trim(107.8): 14 B-trim: 0 in 0/50
Lambda= 0.140140
statistics sampled from 9790 (9797) to 9790 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.681), E-opt: 0.2 (0.301), width: 16
Scan time: 2.670
The best scores are: opt bits E(32554)
CCDS43804.1 TRMT10B gene_id:158234|Hs108|chr9 ( 316) 2105 435.2 3.3e-122
CCDS69601.1 TRMT10B gene_id:158234|Hs108|chr9 ( 221) 1446 301.9 3.1e-82
CCDS69598.1 TRMT10B gene_id:158234|Hs108|chr9 ( 256) 947 201.0 8.2e-52
CCDS69600.1 TRMT10B gene_id:158234|Hs108|chr9 ( 229) 930 197.5 8.1e-51
CCDS3650.1 TRMT10A gene_id:93587|Hs108|chr4 ( 339) 405 91.5 1e-18
CCDS43122.1 TRMT10C gene_id:54931|Hs108|chr3 ( 403) 324 75.1 1e-13
>>CCDS43804.1 TRMT10B gene_id:158234|Hs108|chr9 (316 aa)
initn: 2105 init1: 2105 opt: 2105 Z-score: 2307.5 bits: 435.2 E(32554): 3.3e-122
Smith-Waterman score: 2105; 100.0% identity (100.0% similar) in 316 aa overlap (1-316:1-316)
10 20 30 40 50 60
pF1KE3 MDWKLEGSTQKVESPVLQGQEGILEETGEDGLPEGFQLLQIDAEGECQEGEILATGSTAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 MDWKLEGSTQKVESPVLQGQEGILEETGEDGLPEGFQLLQIDAEGECQEGEILATGSTAW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 CSKNVQRKQRHWEKIVAAKKSKRKQEKERRKANRAENPGICPQHSKRFLRALTKDKLLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 CSKNVQRKQRHWEKIVAAKKSKRKQEKERRKANRAENPGICPQHSKRFLRALTKDKLLEA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 KHSGPRLCIDLSMTHYMSKKELSRLAGQIRRLYGSNKKADRPFWICLTGFTTDSPLYEEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 KHSGPRLCIDLSMTHYMSKKELSRLAGQIRRLYGSNKKADRPFWICLTGFTTDSPLYEEC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 VRMNDGFSSYLLDITEEDCFSLFPLETLVYLTPDSEHALEDVDLNKVYILGGLVDESIQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 VRMNDGFSSYLLDITEEDCFSLFPLETLVYLTPDSEHALEDVDLNKVYILGGLVDESIQK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 KVTFQKAREYSVKTARLPIQEYMVRNQNGKNYHSEILAINQVFDILSTYLETHNWPEALK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 KVTFQKAREYSVKTARLPIQEYMVRNQNGKNYHSEILAINQVFDILSTYLETHNWPEALK
250 260 270 280 290 300
310
pF1KE3 KGVSSGKGYILRNSVE
::::::::::::::::
CCDS43 KGVSSGKGYILRNSVE
310
>>CCDS69601.1 TRMT10B gene_id:158234|Hs108|chr9 (221 aa)
initn: 1446 init1: 1446 opt: 1446 Z-score: 1589.9 bits: 301.9 E(32554): 3.1e-82
Smith-Waterman score: 1446; 100.0% identity (100.0% similar) in 218 aa overlap (99-316:4-221)
70 80 90 100 110 120
pF1KE3 QRHWEKIVAAKKSKRKQEKERRKANRAENPGICPQHSKRFLRALTKDKLLEAKHSGPRLC
::::::::::::::::::::::::::::::
CCDS69 MVLGICPQHSKRFLRALTKDKLLEAKHSGPRLC
10 20 30
130 140 150 160 170 180
pF1KE3 IDLSMTHYMSKKELSRLAGQIRRLYGSNKKADRPFWICLTGFTTDSPLYEECVRMNDGFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS69 IDLSMTHYMSKKELSRLAGQIRRLYGSNKKADRPFWICLTGFTTDSPLYEECVRMNDGFS
40 50 60 70 80 90
190 200 210 220 230 240
pF1KE3 SYLLDITEEDCFSLFPLETLVYLTPDSEHALEDVDLNKVYILGGLVDESIQKKVTFQKAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS69 SYLLDITEEDCFSLFPLETLVYLTPDSEHALEDVDLNKVYILGGLVDESIQKKVTFQKAR
100 110 120 130 140 150
250 260 270 280 290 300
pF1KE3 EYSVKTARLPIQEYMVRNQNGKNYHSEILAINQVFDILSTYLETHNWPEALKKGVSSGKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS69 EYSVKTARLPIQEYMVRNQNGKNYHSEILAINQVFDILSTYLETHNWPEALKKGVSSGKG
160 170 180 190 200 210
310
pF1KE3 YILRNSVE
::::::::
CCDS69 YILRNSVE
220
>>CCDS69598.1 TRMT10B gene_id:158234|Hs108|chr9 (256 aa)
initn: 1510 init1: 947 opt: 947 Z-score: 1043.6 bits: 201.0 E(32554): 8.2e-52
Smith-Waterman score: 1558; 81.0% identity (81.0% similar) in 316 aa overlap (1-316:1-256)
10 20 30 40 50 60
pF1KE3 MDWKLEGSTQKVESPVLQGQEGILEETGEDGLPEGFQLLQIDAEGECQEGEILATGSTAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS69 MDWKLEGSTQKVESPVLQGQEGILEETGEDGLPEGFQLLQIDAEGECQEGEILATGSTAW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 CSKNVQRKQRHWEKIVAAKKSKRKQEKERRKANRAENPGICPQHSKRFLRALTKDKLLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS69 CSKNVQRKQRHWEKIVAAKKSKRKQEKERRKANRAENPGICPQHSKRFLRALTKDKLLEA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 KHSGPRLCIDLSMTHYMSKKELSRLAGQIRRLYGSNKKADRPFWICLTGFTTDSPLYEEC
::::::::::::::::::::
CCDS69 KHSGPRLCIDLSMTHYMSKK----------------------------------------
130 140
190 200 210 220 230 240
pF1KE3 VRMNDGFSSYLLDITEEDCFSLFPLETLVYLTPDSEHALEDVDLNKVYILGGLVDESIQK
:::::::::::::::::::::::::::::::::::::::::::::::::
CCDS69 -----------LDITEEDCFSLFPLETLVYLTPDSEHALEDVDLNKVYILGGLVDESIQK
150 160 170 180
250 260 270 280 290 300
pF1KE3 KVTFQKAREYSVKTARLPIQEYMVRNQNGKNYHSEILAINQVFDILSTYLETHNWPEALK
::::::::::::::::::::::::::::::::::::::::: ::::::::::
CCDS69 KVTFQKAREYSVKTARLPIQEYMVRNQNGKNYHSEILAINQ---------ETHNWPEALK
190 200 210 220 230 240
310
pF1KE3 KGVSSGKGYILRNSVE
::::::::::::::::
CCDS69 KGVSSGKGYILRNSVE
250
>>CCDS69600.1 TRMT10B gene_id:158234|Hs108|chr9 (229 aa)
initn: 930 init1: 930 opt: 930 Z-score: 1025.8 bits: 197.5 E(32554): 8.1e-51
Smith-Waterman score: 1332; 72.5% identity (72.5% similar) in 316 aa overlap (1-316:1-229)
10 20 30 40 50 60
pF1KE3 MDWKLEGSTQKVESPVLQGQEGILEETGEDGLPEGFQLLQIDAEGECQEGEILATGSTAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS69 MDWKLEGSTQKVESPVLQGQEGILEETGEDGLPEGFQLLQIDAEGECQEGEILATGSTAW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 CSKNVQRKQRHWEKIVAAKKSKRKQEKERRKANRAENPGICPQHSKRFLRALTKDKLLEA
::
CCDS69 CS----------------------------------------------------------
130 140 150 160 170 180
pF1KE3 KHSGPRLCIDLSMTHYMSKKELSRLAGQIRRLYGSNKKADRPFWICLTGFTTDSPLYEEC
::::::::::::::::::::::::::::::::::::::::
CCDS69 --------------------ELSRLAGQIRRLYGSNKKADRPFWICLTGFTTDSPLYEEC
70 80 90 100
190 200 210 220 230 240
pF1KE3 VRMNDGFSSYLLDITEEDCFSLFPLETLVYLTPDSEHALEDVDLNKVYILGGLVDESIQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS69 VRMNDGFSSYLLDITEEDCFSLFPLETLVYLTPDSEHALEDVDLNKVYILGGLVDESIQK
110 120 130 140 150 160
250 260 270 280 290 300
pF1KE3 KVTFQKAREYSVKTARLPIQEYMVRNQNGKNYHSEILAINQVFDILSTYLETHNWPEALK
::::::::::::::::::::::::::::::::::::::::: ::::::::::
CCDS69 KVTFQKAREYSVKTARLPIQEYMVRNQNGKNYHSEILAINQ---------ETHNWPEALK
170 180 190 200 210
310
pF1KE3 KGVSSGKGYILRNSVE
::::::::::::::::
CCDS69 KGVSSGKGYILRNSVE
220
>>CCDS3650.1 TRMT10A gene_id:93587|Hs108|chr4 (339 aa)
initn: 448 init1: 173 opt: 405 Z-score: 449.5 bits: 91.5 E(32554): 1e-18
Smith-Waterman score: 405; 29.9% identity (62.4% similar) in 274 aa overlap (41-310:21-279)
20 30 40 50 60
pF1KE3 KVESPVLQGQEGILEETGEDGLPEGFQLLQIDAEGECQEGEILATGSTAWCSKNVQR--K
:. . : .. :. : ...... :
CCDS36 MSSEMLPAFIETSNVDKKQGINEDQEESQKPRLGEGCEPISKRQMKKLIK
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 QRHWEKIVAAKKSKRKQEKERRKANRA-ENPGICPQHSKRFLRALTKDKLLEAKHSGPRL
:..::. .:.:::....:.: .: . :... .: .: . :: ::
CCDS36 QKQWEEQRELRKQKRKEKRKRKKLERQCQMEPNSDGHDRKRVR---RDVV----HSTLRL
60 70 80 90 100
130 140 150 160 170 180
pF1KE3 CIDLSMTHYMSKKELSRLAGQIRRLYGSNKKADRPFWICLTGFTTDSPLYEECVRMNDGF
:: :. : : :....: ::.: :. :..: .: . :: . . : .. . . :.
CCDS36 IIDCSFDHLMVLKDIKKLHKQIQRCYAENRRALHPVQFYLT--SHGGQLKKNMDENDKGW
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE3 SSYL-LDITEEDCFSLFPLETLVYLTPDSEHALEDVDLNKVYILGGLVDESIQKKVTFQK
.. . : : :. : :.::: :: . :...: .:.:..:::::.. .: .:...
CCDS36 VNWKDIHIKPEHYSELIKKEDLIYLTSDSPNILKELDESKAYVIGGLVDHNHHKGLTYKQ
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE3 AREYSVKTARLPIQEYMVRNQNGKNYHSEILAINQVFDILSTYLETHNWPEALKKGVSSG
: .:... :.::. ... :. ..::.:.::.:. ::::..: ::. . .
CCDS36 ASDYGINHAQLPLGNFVKMNSR------KVLAVNHVFEIILEYLETRDWQEAFFTILPQR
230 240 250 260 270
310
pF1KE3 KGYILRNSVE
:: .
CCDS36 KGAVPTDKACESASHDNQSVRMEEGGSDSDSSEEEYSRNELDSPHEEKQDKENHTESTVN
280 290 300 310 320 330
>>CCDS43122.1 TRMT10C gene_id:54931|Hs108|chr3 (403 aa)
initn: 234 init1: 186 opt: 324 Z-score: 359.8 bits: 75.1 E(32554): 1e-13
Smith-Waterman score: 332; 28.7% identity (62.0% similar) in 258 aa overlap (61-300:123-374)
40 50 60 70 80
pF1KE3 GLPEGFQLLQIDAEGECQEGEILATGSTAWCSKNVQRKQRHWEKIVAAKKSK--RKQEKE
: .:. .: .. . . . .: : :. .::
CCDS43 ATREFIEMWRLLGREVPEHITEEELKTLMECVSNTAKK-KYLKYLYTKEKVKKARQIKKE
100 110 120 130 140 150
90 100 110 120 130
pF1KE3 RRKANRAENPGI----CPQHSKR----FLRALTKD-------KLLEAKHSGPRLCIDLSM
. : : : .: ...:. ::: .. : .: . : : .:...
CCDS43 MKAAAREEAKNIKLLETTEEDKQKNFLFLRLWDRNMDIAMGWKGAQAMQFGQPLVFDMAY
160 170 180 190 200 210
140 150 160 170 180 190
pF1KE3 THYMSKKELSRLAGQIRRLYGSNKKADRPFWICLTGFTTDSPLYEECV-RMNDGFSSYLL
.::..:::. ..:. . : :.. :: : . .. :. :..: : :... ... ::
CCDS43 ENYMKRKELQNTVSQLLESEGWNRRNVDPFHIYFCNLKIDGALHRELVKRYQEKWDKLLL
220 230 240 250 260 270
200 210 220 230 240 250
pF1KE3 DITEEDCFSLFPLETLVYLTPDSEHALEDVDLNKVYILGGLVDESIQKKVTFQKAREYSV
::.. .::: ....::: :: ... .:::..:..::.:.: ... ::.. ..
CCDS43 TSTEKSHVDLFPKDSIIYLTADSPNVMTTFRHDKVYVIGSFVDKSMQPGTSLAKAKRLNL
280 290 300 310 320 330
260 270 280 290 300 310
pF1KE3 KTARLPIQEYMVRNQNGKNYHSEILAINQVFDILSTYLETHNWPEALKKGVSSGKGYILR
: ::...:. . ..:: :...:.. :: .. :: :::.
CCDS43 ATECLPLDKYLQWEIGNKN-----LTLDQMIRILLCLKNNGNWQEALQFVPKRKHTGFLE
340 350 360 370 380
pF1KE3 NSVE
CCDS43 ISQHSQEFINRLKKAKT
390 400
316 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 10:54:54 2016 done: Sun Nov 6 10:54:55 2016
Total Scan time: 2.670 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]