FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE3117, 291 aa
  1>>>pF1KE3117 291 - 291 aa - 291 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.9563+/-0.000703; mu= 16.9483+/- 0.042
 mean_var=61.9694+/-12.743, 0's: 0 Z-trim(109.4): 17  B-trim: 0 in 0/50
 Lambda= 0.162924
 statistics sampled from 10823 (10834) to 10823 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.711), E-opt: 0.2 (0.333), width:  16
 Scan time:  2.680

The best scores are:                                      opt bits E(32554)
CCDS44668.1 LRTOMT gene_id:220074|Hs108|chr11      ( 291) 1965 470.1 8.6e-133
CCDS13770.1 COMT gene_id:1312|Hs108|chr22          ( 271)  568 141.7 5.7e-34
CCDS46663.1 COMT gene_id:1312|Hs108|chr22          ( 221)  542 135.5 3.4e-32


>>CCDS44668.1 LRTOMT gene_id:220074|Hs108|chr11           (291 aa)
 initn: 1965 init1: 1965 opt: 1965  Z-score: 2497.5  bits: 470.1 E(32554): 8.6e-133
Smith-Waterman score: 1965; 100.0% identity (100.0% similar) in 291 aa overlap (1-291:1-291)

               10        20        30        40        50        60
pF1KE3 MGTPWRKRKGIAGPGLPDLSCALVLQPRAQVGTMSPAIALAFLPLVVTLLVRYRHYFRLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 MGTPWRKRKGIAGPGLPDLSCALVLQPRAQVGTMSPAIALAFLPLVVTLLVRYRHYFRLL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE3 VRTVLLRSLRDCLSGLRIEERAFSYVLTHALPGDPGHILTTLDHWSSRCEYLSHMGPVKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 VRTVLLRSLRDCLSGLRIEERAFSYVLTHALPGDPGHILTTLDHWSSRCEYLSHMGPVKG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE3 QILMRLVEEKAPACVLELGTYCGYSTLLIARALPPGGRLLTVERDPRTAAVAEKLIRLAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 QILMRLVEEKAPACVLELGTYCGYSTLLIARALPPGGRLLTVERDPRTAAVAEKLIRLAG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE3 FDEHMVELIVGSSEDVIPCLRTQYQLSRADLVLLAHRPRCYLRDLQLLEAHALLPAGATV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 FDEHMVELIVGSSEDVIPCLRTQYQLSRADLVLLAHRPRCYLRDLQLLEAHALLPAGATV
              190       200       210       220       230       240

              250       260       270       280       290 
pF1KE3 LADHVLFPGAPRFLQYAKSCGRYRCRLHHTGLPDFPAIKDGIAQLTYAGPG
       :::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 LADHVLFPGAPRFLQYAKSCGRYRCRLHHTGLPDFPAIKDGIAQLTYAGPG
              250       260       270       280       290 

>>CCDS13770.1 COMT gene_id:1312|Hs108|chr22               (271 aa)
 initn: 530 init1: 276 opt: 568  Z-score: 723.3  bits: 141.7 E(32554): 5.7e-34
Smith-Waterman score: 568; 36.3% identity (67.2% similar) in 259 aa overlap (37-291:10-266)

         10        20        30        40        50        60      
pF1KE3 KRKGIAGPGLPDLSCALVLQPRAQVGTMSPAIALAFLPLVVTLLVRYRHYFRLLV----R
                                     : .:  : :.:.::.  ::.   :      
CCDS13                      MPEAPPLLLAAVLLGLVLLVVLLLLLRHWGWGLCLIGWN
                                    10        20        30         

             70        80        90       100       110       120  
pF1KE3 TVLLRSLRDCLSGLRIEERAFSYVLTHALPGDPGHILTTLDHWSSRCEYLSHMGPVKGQI
         .:. ... : :   :.: ...:: :: ::.   .: ..: .  . :.  ..:  ::.:
CCDS13 EFILQPIHNLLMGDTKEQRILNHVLQHAEPGNAQSVLEAIDTYCEQKEWAMNVGDKKGKI
      40        50        60        70        80        90         

            130       140       150       160       170       180  
pF1KE3 LMRLVEEKAPACVLELGTYCGYSTLLIARALPPGGRLLTVERDPRTAAVAEKLIRLAGFD
       .  ...:. :. .::::.:::::.. .:: : ::.::.:.: .:  ::...... .::  
CCDS13 VDAVIQEHQPSVLLELGAYCGYSAVRMARLLSPGARLITIEINPDCAAITQRMVDFAGVK
     100       110       120       130       140       150         

            190       200       210       220       230       240  
pF1KE3 EHMVELIVGSSEDVIPCLRTQYQLSRADLVLLAHRPRCYLRDLQLLEAHALLPAGATVLA
       .. : :.::.:.:.:: :. .:...  :.:.: :    :: :  :::  .::  :...::
CCDS13 DK-VTLVVGASQDIIPQLKKKYDVDTLDMVFLDHWKDRYLPDTLLLEECGLLRKGTVLLA
     160        170       180       190       200       210        

            250       260       270       280       290      
pF1KE3 DHVLFPGAPRFLQYAKSCGRYRCRLHHTGLPDFPAIKDGIAQLTYAGPG     
       :.:. :::: :: .... . ..:  :. .. ..  . ::. .  : :::     
CCDS13 DNVICPGAPDFLAHVRGSSCFECT-HYQSFLEYREVVDGLEKAIYKGPGSEAGP
      220       230       240        250       260       270 

>>CCDS46663.1 COMT gene_id:1312|Hs108|chr22               (221 aa)
 initn: 530 init1: 276 opt: 542  Z-score: 691.6  bits: 135.5 E(32554): 3.4e-32
Smith-Waterman score: 542; 38.0% identity (70.9% similar) in 213 aa overlap (79-291:6-216)

       50        60        70        80        90       100        
pF1KE3 LLVRYRHYFRLLVRTVLLRSLRDCLSGLRIEERAFSYVLTHALPGDPGHILTTLDHWSSR
                                     :.: ...:: :: ::.   .: ..: .  .
CCDS46                          MGDTKEQRILNHVLQHAEPGNAQSVLEAIDTYCEQ
                                        10        20        30     

      110       120       130       140       150       160        
pF1KE3 CEYLSHMGPVKGQILMRLVEEKAPACVLELGTYCGYSTLLIARALPPGGRLLTVERDPRT
        :.  ..:  ::.:.  ...:. :. .::::.:::::.. .:: : ::.::.:.: .:  
CCDS46 KEWAMNVGDKKGKIVDAVIQEHQPSVLLELGAYCGYSAVRMARLLSPGARLITIEINPDC
          40        50        60        70        80        90     

      170       180       190       200       210       220        
pF1KE3 AAVAEKLIRLAGFDEHMVELIVGSSEDVIPCLRTQYQLSRADLVLLAHRPRCYLRDLQLL
       ::...... .::  .. : :.::.:.:.:: :. .:...  :.:.: :    :: :  ::
CCDS46 AAITQRMVDFAGVKDK-VTLVVGASQDIIPQLKKKYDVDTLDMVFLDHWKDRYLPDTLLL
         100       110        120       130       140       150    

      230       240       250       260       270       280        
pF1KE3 EAHALLPAGATVLADHVLFPGAPRFLQYAKSCGRYRCRLHHTGLPDFPAIKDGIAQLTYA
       :  .::  :...:::.:. :::: :: .... . ..:  :. .. ..  . ::. .  : 
CCDS46 EECGLLRKGTVLLADNVICPGAPDFLAHVRGSSCFECT-HYQSFLEYREVVDGLEKAIYK
          160       170       180       190        200       210   

      290      
pF1KE3 GPG     
       :::     
CCDS46 GPGSEAGP
           220 




291 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sun Nov  6 05:32:23 2016 done: Sun Nov  6 05:32:24 2016
 Total Scan time:  2.680 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]