Result of FASTA (omim) for
pFN21AE3107
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3107, 277 aa
1>>>pF1KE3107 277 - 277 aa - 277 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.6192+/-0.000382; mu= 19.0581+/- 0.024
mean_var=66.2959+/-13.489, 0's: 0 Z-trim(112.5): 23 B-trim: 722 in 1/51
Lambda= 0.157518
statistics sampled from 21455 (21478) to 21455 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.637), E-opt: 0.2 (0.252), width: 16
Scan time: 6.630
The best scores are: opt bits E(85289)
NP_550438 (OMIM: 251880,601465,617068,617070) deox ( 277) 1842 427.4 1.4e-119
XP_011530949 (OMIM: 251880,601465,617068,617070) P ( 271) 1782 413.8 1.8e-115
NP_001305789 (OMIM: 251880,601465,617068,617070) d ( 180) 1211 283.8 1.5e-76
NP_001305790 (OMIM: 251880,601465,617068,617070) d ( 180) 1211 283.8 1.5e-76
NP_001305792 (OMIM: 251880,601465,617068,617070) d ( 174) 1151 270.2 1.9e-72
NP_001305791 (OMIM: 251880,601465,617068,617070) d ( 174) 1151 270.2 1.9e-72
NP_550440 (OMIM: 251880,601465,617068,617070) deox ( 189) 977 230.7 1.6e-60
NP_001305788 (OMIM: 251880,601465,617068,617070) d ( 183) 936 221.4 1e-57
NP_000779 (OMIM: 125450) deoxycytidine kinase [Hom ( 260) 846 201.0 1.9e-51
NP_001258979 (OMIM: 188250,609560,617069) thymidin ( 168) 289 74.3 1.7e-13
NP_001258863 (OMIM: 188250,609560,617069) thymidin ( 216) 289 74.4 2.1e-13
NP_001166114 (OMIM: 188250,609560,617069) thymidin ( 234) 289 74.4 2.2e-13
NP_001166115 (OMIM: 188250,609560,617069) thymidin ( 240) 289 74.4 2.2e-13
NP_001166116 (OMIM: 188250,609560,617069) thymidin ( 247) 289 74.4 2.3e-13
NP_004605 (OMIM: 188250,609560,617069) thymidine k ( 265) 289 74.5 2.4e-13
NP_001308949 (OMIM: 256000,603835) NADH dehydrogen ( 317) 150 43.0 0.00088
NP_004535 (OMIM: 256000,603835) NADH dehydrogenase ( 355) 150 43.0 0.00095
XP_011509530 (OMIM: 256000,603835) PREDICTED: NADH ( 362) 150 43.0 0.00097
NP_001308948 (OMIM: 256000,603835) NADH dehydrogen ( 375) 150 43.0 0.00099
NP_001258864 (OMIM: 188250,609560,617069) thymidin ( 146) 133 38.8 0.0073
>>NP_550438 (OMIM: 251880,601465,617068,617070) deoxygua (277 aa)
initn: 1842 init1: 1842 opt: 1842 Z-score: 2267.7 bits: 427.4 E(85289): 1.4e-119
Smith-Waterman score: 1842; 100.0% identity (100.0% similar) in 277 aa overlap (1-277:1-277)
10 20 30 40 50 60
pF1KE3 MAAGRLFLSRLRAPFSSMAKSPLEGVSSSRGLHAGRGPRRLSIEGNIAVGKSTFVKLLTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_550 MAAGRLFLSRLRAPFSSMAKSPLEGVSSSRGLHAGRGPRRLSIEGNIAVGKSTFVKLLTK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 TYPEWHVATEPVATWQNIQAAGTQKACTAQSLGNLLDMMYREPARWSYTFQTFSFLSRLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_550 TYPEWHVATEPVATWQNIQAAGTQKACTAQSLGNLLDMMYREPARWSYTFQTFSFLSRLK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 VQLEPFPEKLLQARKPVQIFERSVYSDRYIFAKNLFENGSLSDIEWHIYQDWHSFLLWEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_550 VQLEPFPEKLLQARKPVQIFERSVYSDRYIFAKNLFENGSLSDIEWHIYQDWHSFLLWEF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 ASRITLHGFIYLQASPQVCLKRLYQRAREEEKGIELAYLEQLHGQHEAWLIHKTTKLHFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_550 ASRITLHGFIYLQASPQVCLKRLYQRAREEEKGIELAYLEQLHGQHEAWLIHKTTKLHFE
190 200 210 220 230 240
250 260 270
pF1KE3 ALMNIPVLVLDVNDDFSEEVTKQEDLMREVNTFVKNL
:::::::::::::::::::::::::::::::::::::
NP_550 ALMNIPVLVLDVNDDFSEEVTKQEDLMREVNTFVKNL
250 260 270
>>XP_011530949 (OMIM: 251880,601465,617068,617070) PREDI (271 aa)
initn: 985 init1: 945 opt: 1782 Z-score: 2194.2 bits: 413.8 E(85289): 1.8e-115
Smith-Waterman score: 1782; 97.8% identity (97.8% similar) in 277 aa overlap (1-277:1-271)
10 20 30 40 50 60
pF1KE3 MAAGRLFLSRLRAPFSSMAKSPLEGVSSSRGLHAGRGPRRLSIEGNIAVGKSTFVKLLTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAAGRLFLSRLRAPFSSMAKSPLEGVSSSRGLHAGRGPRRLSIEGNIAVGKSTFVKLLTK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 TYPEWHVATEPVATWQNIQAAGTQKACTAQSLGNLLDMMYREPARWSYTFQTFSFLSRLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TYPEWHVATEPVATWQNIQAAGTQKACTAQSLGNLLDMMYREPARWSYTFQTFSFLSRLK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 VQLEPFPEKLLQARKPVQIFERSVYSDRYIFAKNLFENGSLSDIEWHIYQDWHSFLLWEF
:::::::::::::::::::::: ::::::::::::::::::::::::::::::::
XP_011 VQLEPFPEKLLQARKPVQIFER------YIFAKNLFENGSLSDIEWHIYQDWHSFLLWEF
130 140 150 160 170
190 200 210 220 230 240
pF1KE3 ASRITLHGFIYLQASPQVCLKRLYQRAREEEKGIELAYLEQLHGQHEAWLIHKTTKLHFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASRITLHGFIYLQASPQVCLKRLYQRAREEEKGIELAYLEQLHGQHEAWLIHKTTKLHFE
180 190 200 210 220 230
250 260 270
pF1KE3 ALMNIPVLVLDVNDDFSEEVTKQEDLMREVNTFVKNL
:::::::::::::::::::::::::::::::::::::
XP_011 ALMNIPVLVLDVNDDFSEEVTKQEDLMREVNTFVKNL
240 250 260 270
>>NP_001305789 (OMIM: 251880,601465,617068,617070) deoxy (180 aa)
initn: 1211 init1: 1211 opt: 1211 Z-score: 1495.2 bits: 283.8 E(85289): 1.5e-76
Smith-Waterman score: 1211; 100.0% identity (100.0% similar) in 180 aa overlap (98-277:1-180)
70 80 90 100 110 120
pF1KE3 ATEPVATWQNIQAAGTQKACTAQSLGNLLDMMYREPARWSYTFQTFSFLSRLKVQLEPFP
::::::::::::::::::::::::::::::
NP_001 MMYREPARWSYTFQTFSFLSRLKVQLEPFP
10 20 30
130 140 150 160 170 180
pF1KE3 EKLLQARKPVQIFERSVYSDRYIFAKNLFENGSLSDIEWHIYQDWHSFLLWEFASRITLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKLLQARKPVQIFERSVYSDRYIFAKNLFENGSLSDIEWHIYQDWHSFLLWEFASRITLH
40 50 60 70 80 90
190 200 210 220 230 240
pF1KE3 GFIYLQASPQVCLKRLYQRAREEEKGIELAYLEQLHGQHEAWLIHKTTKLHFEALMNIPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFIYLQASPQVCLKRLYQRAREEEKGIELAYLEQLHGQHEAWLIHKTTKLHFEALMNIPV
100 110 120 130 140 150
250 260 270
pF1KE3 LVLDVNDDFSEEVTKQEDLMREVNTFVKNL
::::::::::::::::::::::::::::::
NP_001 LVLDVNDDFSEEVTKQEDLMREVNTFVKNL
160 170 180
>>NP_001305790 (OMIM: 251880,601465,617068,617070) deoxy (180 aa)
initn: 1211 init1: 1211 opt: 1211 Z-score: 1495.2 bits: 283.8 E(85289): 1.5e-76
Smith-Waterman score: 1211; 100.0% identity (100.0% similar) in 180 aa overlap (98-277:1-180)
70 80 90 100 110 120
pF1KE3 ATEPVATWQNIQAAGTQKACTAQSLGNLLDMMYREPARWSYTFQTFSFLSRLKVQLEPFP
::::::::::::::::::::::::::::::
NP_001 MMYREPARWSYTFQTFSFLSRLKVQLEPFP
10 20 30
130 140 150 160 170 180
pF1KE3 EKLLQARKPVQIFERSVYSDRYIFAKNLFENGSLSDIEWHIYQDWHSFLLWEFASRITLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKLLQARKPVQIFERSVYSDRYIFAKNLFENGSLSDIEWHIYQDWHSFLLWEFASRITLH
40 50 60 70 80 90
190 200 210 220 230 240
pF1KE3 GFIYLQASPQVCLKRLYQRAREEEKGIELAYLEQLHGQHEAWLIHKTTKLHFEALMNIPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFIYLQASPQVCLKRLYQRAREEEKGIELAYLEQLHGQHEAWLIHKTTKLHFEALMNIPV
100 110 120 130 140 150
250 260 270
pF1KE3 LVLDVNDDFSEEVTKQEDLMREVNTFVKNL
::::::::::::::::::::::::::::::
NP_001 LVLDVNDDFSEEVTKQEDLMREVNTFVKNL
160 170 180
>>NP_001305792 (OMIM: 251880,601465,617068,617070) deoxy (174 aa)
initn: 896 init1: 877 opt: 1151 Z-score: 1421.7 bits: 270.2 E(85289): 1.9e-72
Smith-Waterman score: 1151; 96.7% identity (96.7% similar) in 180 aa overlap (98-277:1-174)
70 80 90 100 110 120
pF1KE3 ATEPVATWQNIQAAGTQKACTAQSLGNLLDMMYREPARWSYTFQTFSFLSRLKVQLEPFP
::::::::::::::::::::::::::::::
NP_001 MMYREPARWSYTFQTFSFLSRLKVQLEPFP
10 20 30
130 140 150 160 170 180
pF1KE3 EKLLQARKPVQIFERSVYSDRYIFAKNLFENGSLSDIEWHIYQDWHSFLLWEFASRITLH
::::::::::::::: :::::::::::::::::::::::::::::::::::::::
NP_001 EKLLQARKPVQIFER------YIFAKNLFENGSLSDIEWHIYQDWHSFLLWEFASRITLH
40 50 60 70 80
190 200 210 220 230 240
pF1KE3 GFIYLQASPQVCLKRLYQRAREEEKGIELAYLEQLHGQHEAWLIHKTTKLHFEALMNIPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFIYLQASPQVCLKRLYQRAREEEKGIELAYLEQLHGQHEAWLIHKTTKLHFEALMNIPV
90 100 110 120 130 140
250 260 270
pF1KE3 LVLDVNDDFSEEVTKQEDLMREVNTFVKNL
::::::::::::::::::::::::::::::
NP_001 LVLDVNDDFSEEVTKQEDLMREVNTFVKNL
150 160 170
>>NP_001305791 (OMIM: 251880,601465,617068,617070) deoxy (174 aa)
initn: 896 init1: 877 opt: 1151 Z-score: 1421.7 bits: 270.2 E(85289): 1.9e-72
Smith-Waterman score: 1151; 96.7% identity (96.7% similar) in 180 aa overlap (98-277:1-174)
70 80 90 100 110 120
pF1KE3 ATEPVATWQNIQAAGTQKACTAQSLGNLLDMMYREPARWSYTFQTFSFLSRLKVQLEPFP
::::::::::::::::::::::::::::::
NP_001 MMYREPARWSYTFQTFSFLSRLKVQLEPFP
10 20 30
130 140 150 160 170 180
pF1KE3 EKLLQARKPVQIFERSVYSDRYIFAKNLFENGSLSDIEWHIYQDWHSFLLWEFASRITLH
::::::::::::::: :::::::::::::::::::::::::::::::::::::::
NP_001 EKLLQARKPVQIFER------YIFAKNLFENGSLSDIEWHIYQDWHSFLLWEFASRITLH
40 50 60 70 80
190 200 210 220 230 240
pF1KE3 GFIYLQASPQVCLKRLYQRAREEEKGIELAYLEQLHGQHEAWLIHKTTKLHFEALMNIPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFIYLQASPQVCLKRLYQRAREEEKGIELAYLEQLHGQHEAWLIHKTTKLHFEALMNIPV
90 100 110 120 130 140
250 260 270
pF1KE3 LVLDVNDDFSEEVTKQEDLMREVNTFVKNL
::::::::::::::::::::::::::::::
NP_001 LVLDVNDDFSEEVTKQEDLMREVNTFVKNL
150 160 170
>>NP_550440 (OMIM: 251880,601465,617068,617070) deoxygua (189 aa)
initn: 974 init1: 974 opt: 977 Z-score: 1207.5 bits: 230.7 E(85289): 1.6e-60
Smith-Waterman score: 1047; 68.2% identity (68.2% similar) in 277 aa overlap (1-277:1-189)
10 20 30 40 50 60
pF1KE3 MAAGRLFLSRLRAPFSSMAKSPLEGVSSSRGLHAGRGPRRLSIEGNIAVGKSTFVKLLTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_550 MAAGRLFLSRLRAPFSSMAKSPLEGVSSSRGLHAGRGPRRLSIEGNIAVGKSTFVKLLTK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 TYPEWHVATEPVATWQNIQAAGTQKACTAQSLGNLLDMMYREPARWSYTFQTFSFLSRLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_550 TYPEWHVATEPVATWQNIQAAGTQKACTAQSLGNLLDMMYREPARWSYTFQTFSFLSRLK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 VQLEPFPEKLLQARKPVQIFERSVYSDRYIFAKNLFENGSLSDIEWHIYQDWHSFLLWEF
::::::::::::::::::::::::::::
NP_550 VQLEPFPEKLLQARKPVQIFERSVYSDR--------------------------------
130 140
190 200 210 220 230 240
pF1KE3 ASRITLHGFIYLQASPQVCLKRLYQRAREEEKGIELAYLEQLHGQHEAWLIHKTTKLHFE
::::
NP_550 --------------------------------------------------------LHFE
150
250 260 270
pF1KE3 ALMNIPVLVLDVNDDFSEEVTKQEDLMREVNTFVKNL
:::::::::::::::::::::::::::::::::::::
NP_550 ALMNIPVLVLDVNDDFSEEVTKQEDLMREVNTFVKNL
160 170 180
>>NP_001305788 (OMIM: 251880,601465,617068,617070) deoxy (183 aa)
initn: 936 init1: 936 opt: 936 Z-score: 1157.4 bits: 221.4 E(85289): 1e-57
Smith-Waterman score: 997; 66.1% identity (66.1% similar) in 277 aa overlap (1-277:1-183)
10 20 30 40 50 60
pF1KE3 MAAGRLFLSRLRAPFSSMAKSPLEGVSSSRGLHAGRGPRRLSIEGNIAVGKSTFVKLLTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAGRLFLSRLRAPFSSMAKSPLEGVSSSRGLHAGRGPRRLSIEGNIAVGKSTFVKLLTK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 TYPEWHVATEPVATWQNIQAAGTQKACTAQSLGNLLDMMYREPARWSYTFQTFSFLSRLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TYPEWHVATEPVATWQNIQAAGTQKACTAQSLGNLLDMMYREPARWSYTFQTFSFLSRLK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 VQLEPFPEKLLQARKPVQIFERSVYSDRYIFAKNLFENGSLSDIEWHIYQDWHSFLLWEF
::::::::::::::::::::::
NP_001 VQLEPFPEKLLQARKPVQIFER--------------------------------------
130 140
190 200 210 220 230 240
pF1KE3 ASRITLHGFIYLQASPQVCLKRLYQRAREEEKGIELAYLEQLHGQHEAWLIHKTTKLHFE
::::
NP_001 --------------------------------------------------------LHFE
250 260 270
pF1KE3 ALMNIPVLVLDVNDDFSEEVTKQEDLMREVNTFVKNL
:::::::::::::::::::::::::::::::::::::
NP_001 ALMNIPVLVLDVNDDFSEEVTKQEDLMREVNTFVKNL
150 160 170 180
>>NP_000779 (OMIM: 125450) deoxycytidine kinase [Homo sa (260 aa)
initn: 835 init1: 671 opt: 846 Z-score: 1044.8 bits: 201.0 E(85289): 1.9e-51
Smith-Waterman score: 846; 47.5% identity (77.9% similar) in 263 aa overlap (18-277:1-260)
10 20 30 40 50 60
pF1KE3 MAAGRLFLSRLRAPFSSMAKSPLEGVSSSRGLHAGRGPRRLSIEGNIAVGKSTFVKLLTK
:: : .. : . : ...:::::::.::::::..: .
NP_000 MATPPKRSCPSFSASSEGTRIKKISIEGNIAAGKSTFVNILKQ
10 20 30 40
70 80 90 100 110
pF1KE3 TYPEWHVATEPVATWQNIQAAGTQ---KACTAQSLGNLLDMMYREPARWSYTFQTFSFLS
.:.:. :::: : :.:.. . . . .. ::.:.:::..: :::.::::.. ::
NP_000 LCEDWEVVPEPVARWCNVQSTQDEFEELTMSQKNGGNVLQMMYEKPERWSFTFQTYACLS
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE3 RLKVQLEPFPEKLLQARKPVQIFERSVYSDRYIFAKNLFENGSLSDIEWHIYQDWHSFLL
:...:: . :: .:.::: .:::::::::::::.::.:. ... :: ::::::...
NP_000 RIRAQLASLNGKLKDAEKPVLFFERSVYSDRYIFASNLYESECMNETEWTIYQDWHDWMN
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE3 WEFASRITLHGFIYLQASPQVCLKRLYQRAREEEKGIELAYLEQLHGQHEAWLIHKTTKL
.:.. . : :.:::::.:..::.:.: :.:.::.:: : :::.:: .::.::.:.: :
NP_000 NQFGQSLELDGIIYLQATPETCLHRIYLRGRNEEQGIPLEYLEKLHYKHESWLLHRTLKT
170 180 190 200 210 220
240 250 260 270
pF1KE3 HFEALMNIPVLVLDVNDDFSEEVTKQEDLMREVNTFVKNL
.:. :...:.:.::::.::.. : :.:...:. :...:
NP_000 NFDYLQEVPILTLDVNEDFKD---KYESLVEKVKEFLSTL
230 240 250 260
>>NP_001258979 (OMIM: 188250,609560,617069) thymidine ki (168 aa)
initn: 340 init1: 164 opt: 289 Z-score: 363.2 bits: 74.3 E(85289): 1.7e-13
Smith-Waterman score: 328; 35.5% identity (69.0% similar) in 155 aa overlap (99-253:1-141)
70 80 90 100 110 120
pF1KE3 TEPVATWQNIQAAGTQKACTAQSLGNLLDMMYREPARWSYTFQTFSFLSRLKVQLEPFPE
::.. .::. :.::. :. : . .:
NP_001 MYHDASRWGLTLQTYVQLTMLDRHTRP---
10 20
130 140 150 160 170 180
pF1KE3 KLLQARKPVQIFERSVYSDRYIFAKNLFENGSLSDIEWHIYQDWHSFLLWEFASRITLHG
:. . :...:::..: ::::..::...:.. .... . ..: ...: .. . :
NP_001 ---QV-SSVRLMERSIHSARYIFVENLYRSGKMPEVDYVVLSEWFDWILRNMDVSVDL--
30 40 50 60 70 80
190 200 210 220 230 240
pF1KE3 FIYLQASPQVCLKRLYQRAREEEKGIELAYLEQLHGQHEAWLIHKTTKLHFEALMNIPVL
..::...:..: .:: .: ::::: : : ::: .: :: :::. . : : :::
NP_001 IVYLRTNPETCYQRLKKRCREEEKVIPLEYLEAIHHLHEEWLIKGSL---FP--MAAPVL
90 100 110 120 130
250 260 270
pF1KE3 VLDVNDDFSEEVTKQEDLMREVNTFVKNL
:....
NP_001 VIEADHHMERMLELFEQNRDRILTPENRKHCP
140 150 160
277 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 16:19:37 2016 done: Mon Nov 7 16:19:38 2016
Total Scan time: 6.630 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]