Result of FASTA (ccds) for
pFN21AE3107
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3107, 277 aa
1>>>pF1KE3107 277 - 277 aa - 277 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2633+/-0.000862; mu= 15.1535+/- 0.052
mean_var=62.8509+/-12.566, 0's: 0 Z-trim(105.7): 15 B-trim: 0 in 0/49
Lambda= 0.161778
statistics sampled from 8552 (8562) to 8552 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.649), E-opt: 0.2 (0.263), width: 16
Scan time: 2.030
The best scores are: opt bits E(32554)
CCDS1931.1 DGUOK gene_id:1716|Hs108|chr2 ( 277) 1842 438.5 2.6e-123
CCDS1932.1 DGUOK gene_id:1716|Hs108|chr2 ( 189) 977 236.5 1.1e-62
CCDS3548.1 DCK gene_id:1633|Hs108|chr4 ( 260) 846 206.0 2.3e-53
CCDS61955.1 TK2 gene_id:7084|Hs108|chr16 ( 168) 289 75.9 2.2e-14
CCDS54018.1 TK2 gene_id:7084|Hs108|chr16 ( 234) 289 76.0 2.9e-14
CCDS54016.1 TK2 gene_id:7084|Hs108|chr16 ( 240) 289 76.0 2.9e-14
CCDS54017.1 TK2 gene_id:7084|Hs108|chr16 ( 247) 289 76.0 3e-14
CCDS10805.2 TK2 gene_id:7084|Hs108|chr16 ( 265) 289 76.0 3.2e-14
>>CCDS1931.1 DGUOK gene_id:1716|Hs108|chr2 (277 aa)
initn: 1842 init1: 1842 opt: 1842 Z-score: 2327.4 bits: 438.5 E(32554): 2.6e-123
Smith-Waterman score: 1842; 100.0% identity (100.0% similar) in 277 aa overlap (1-277:1-277)
10 20 30 40 50 60
pF1KE3 MAAGRLFLSRLRAPFSSMAKSPLEGVSSSRGLHAGRGPRRLSIEGNIAVGKSTFVKLLTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS19 MAAGRLFLSRLRAPFSSMAKSPLEGVSSSRGLHAGRGPRRLSIEGNIAVGKSTFVKLLTK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 TYPEWHVATEPVATWQNIQAAGTQKACTAQSLGNLLDMMYREPARWSYTFQTFSFLSRLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS19 TYPEWHVATEPVATWQNIQAAGTQKACTAQSLGNLLDMMYREPARWSYTFQTFSFLSRLK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 VQLEPFPEKLLQARKPVQIFERSVYSDRYIFAKNLFENGSLSDIEWHIYQDWHSFLLWEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS19 VQLEPFPEKLLQARKPVQIFERSVYSDRYIFAKNLFENGSLSDIEWHIYQDWHSFLLWEF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 ASRITLHGFIYLQASPQVCLKRLYQRAREEEKGIELAYLEQLHGQHEAWLIHKTTKLHFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS19 ASRITLHGFIYLQASPQVCLKRLYQRAREEEKGIELAYLEQLHGQHEAWLIHKTTKLHFE
190 200 210 220 230 240
250 260 270
pF1KE3 ALMNIPVLVLDVNDDFSEEVTKQEDLMREVNTFVKNL
:::::::::::::::::::::::::::::::::::::
CCDS19 ALMNIPVLVLDVNDDFSEEVTKQEDLMREVNTFVKNL
250 260 270
>>CCDS1932.1 DGUOK gene_id:1716|Hs108|chr2 (189 aa)
initn: 974 init1: 974 opt: 977 Z-score: 1238.9 bits: 236.5 E(32554): 1.1e-62
Smith-Waterman score: 1047; 68.2% identity (68.2% similar) in 277 aa overlap (1-277:1-189)
10 20 30 40 50 60
pF1KE3 MAAGRLFLSRLRAPFSSMAKSPLEGVSSSRGLHAGRGPRRLSIEGNIAVGKSTFVKLLTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS19 MAAGRLFLSRLRAPFSSMAKSPLEGVSSSRGLHAGRGPRRLSIEGNIAVGKSTFVKLLTK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 TYPEWHVATEPVATWQNIQAAGTQKACTAQSLGNLLDMMYREPARWSYTFQTFSFLSRLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS19 TYPEWHVATEPVATWQNIQAAGTQKACTAQSLGNLLDMMYREPARWSYTFQTFSFLSRLK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 VQLEPFPEKLLQARKPVQIFERSVYSDRYIFAKNLFENGSLSDIEWHIYQDWHSFLLWEF
::::::::::::::::::::::::::::
CCDS19 VQLEPFPEKLLQARKPVQIFERSVYSDR--------------------------------
130 140
190 200 210 220 230 240
pF1KE3 ASRITLHGFIYLQASPQVCLKRLYQRAREEEKGIELAYLEQLHGQHEAWLIHKTTKLHFE
::::
CCDS19 --------------------------------------------------------LHFE
150
250 260 270
pF1KE3 ALMNIPVLVLDVNDDFSEEVTKQEDLMREVNTFVKNL
:::::::::::::::::::::::::::::::::::::
CCDS19 ALMNIPVLVLDVNDDFSEEVTKQEDLMREVNTFVKNL
160 170 180
>>CCDS3548.1 DCK gene_id:1633|Hs108|chr4 (260 aa)
initn: 835 init1: 671 opt: 846 Z-score: 1071.5 bits: 206.0 E(32554): 2.3e-53
Smith-Waterman score: 846; 47.5% identity (77.9% similar) in 263 aa overlap (18-277:1-260)
10 20 30 40 50 60
pF1KE3 MAAGRLFLSRLRAPFSSMAKSPLEGVSSSRGLHAGRGPRRLSIEGNIAVGKSTFVKLLTK
:: : .. : . : ...:::::::.::::::..: .
CCDS35 MATPPKRSCPSFSASSEGTRIKKISIEGNIAAGKSTFVNILKQ
10 20 30 40
70 80 90 100 110
pF1KE3 TYPEWHVATEPVATWQNIQAAGTQ---KACTAQSLGNLLDMMYREPARWSYTFQTFSFLS
.:.:. :::: : :.:.. . . . .. ::.:.:::..: :::.::::.. ::
CCDS35 LCEDWEVVPEPVARWCNVQSTQDEFEELTMSQKNGGNVLQMMYEKPERWSFTFQTYACLS
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE3 RLKVQLEPFPEKLLQARKPVQIFERSVYSDRYIFAKNLFENGSLSDIEWHIYQDWHSFLL
:...:: . :: .:.::: .:::::::::::::.::.:. ... :: ::::::...
CCDS35 RIRAQLASLNGKLKDAEKPVLFFERSVYSDRYIFASNLYESECMNETEWTIYQDWHDWMN
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE3 WEFASRITLHGFIYLQASPQVCLKRLYQRAREEEKGIELAYLEQLHGQHEAWLIHKTTKL
.:.. . : :.:::::.:..::.:.: :.:.::.:: : :::.:: .::.::.:.: :
CCDS35 NQFGQSLELDGIIYLQATPETCLHRIYLRGRNEEQGIPLEYLEKLHYKHESWLLHRTLKT
170 180 190 200 210 220
240 250 260 270
pF1KE3 HFEALMNIPVLVLDVNDDFSEEVTKQEDLMREVNTFVKNL
.:. :...:.:.::::.::.. : :.:...:. :...:
CCDS35 NFDYLQEVPILTLDVNEDFKD---KYESLVEKVKEFLSTL
230 240 250 260
>>CCDS61955.1 TK2 gene_id:7084|Hs108|chr16 (168 aa)
initn: 340 init1: 164 opt: 289 Z-score: 371.8 bits: 75.9 E(32554): 2.2e-14
Smith-Waterman score: 328; 35.5% identity (69.0% similar) in 155 aa overlap (99-253:1-141)
70 80 90 100 110 120
pF1KE3 TEPVATWQNIQAAGTQKACTAQSLGNLLDMMYREPARWSYTFQTFSFLSRLKVQLEPFPE
::.. .::. :.::. :. : . .:
CCDS61 MYHDASRWGLTLQTYVQLTMLDRHTRP---
10 20
130 140 150 160 170 180
pF1KE3 KLLQARKPVQIFERSVYSDRYIFAKNLFENGSLSDIEWHIYQDWHSFLLWEFASRITLHG
:. . :...:::..: ::::..::...:.. .... . ..: ...: .. . :
CCDS61 ---QV-SSVRLMERSIHSARYIFVENLYRSGKMPEVDYVVLSEWFDWILRNMDVSVDL--
30 40 50 60 70 80
190 200 210 220 230 240
pF1KE3 FIYLQASPQVCLKRLYQRAREEEKGIELAYLEQLHGQHEAWLIHKTTKLHFEALMNIPVL
..::...:..: .:: .: ::::: : : ::: .: :: :::. . : : :::
CCDS61 IVYLRTNPETCYQRLKKRCREEEKVIPLEYLEAIHHLHEEWLIKGSL---FP--MAAPVL
90 100 110 120 130
250 260 270
pF1KE3 VLDVNDDFSEEVTKQEDLMREVNTFVKNL
:....
CCDS61 VIEADHHMERMLELFEQNRDRILTPENRKHCP
140 150 160
>>CCDS54018.1 TK2 gene_id:7084|Hs108|chr16 (234 aa)
initn: 425 init1: 164 opt: 289 Z-score: 369.6 bits: 76.0 E(32554): 2.9e-14
Smith-Waterman score: 404; 33.8% identity (66.7% similar) in 213 aa overlap (41-253:22-207)
20 30 40 50 60 70
pF1KE3 LRAPFSSMAKSPLEGVSSSRGLHAGRGPRRLSIEGNIAVGKSTFVKLLTKTYPEWHVATE
. .::::: ::.: ....... . .: ::
CCDS54 MGAFCQRPSSDKEQEKEKKSVICVEGNIASGKTTCLEFFSNA-TDVEVLTE
10 20 30 40 50
80 90 100 110 120 130
pF1KE3 PVATWQNIQAAGTQKACTAQSLGNLLDMMYREPARWSYTFQTFSFLSRLKVQLEPFPEKL
::. :.:... : : .::.. .::. :.::. :. : . .:
CCDS54 PVSKWRNVRGH------------NPLGLMYHDASRWGLTLQTYVQLTMLDRHTRP-----
60 70 80 90
140 150 160 170 180 190
pF1KE3 LQARKPVQIFERSVYSDRYIFAKNLFENGSLSDIEWHIYQDWHSFLLWEFASRITLHGFI
:. . :...:::..: ::::..::...:.. .... . ..: ...: .. . : ..
CCDS54 -QVSS-VRLMERSIHSARYIFVENLYRSGKMPEVDYVVLSEWFDWILRNMDVSVDL--IV
100 110 120 130 140
200 210 220 230 240 250
pF1KE3 YLQASPQVCLKRLYQRAREEEKGIELAYLEQLHGQHEAWLIHKTTKLHFEALMNIPVLVL
::...:..: .:: .: ::::: : : ::: .: :: :::. . : : ::::.
CCDS54 YLRTNPETCYQRLKKRCREEEKVIPLEYLEAIHHLHEEWLIKGSL---FP--MAAPVLVI
150 160 170 180 190 200
260 270
pF1KE3 DVNDDFSEEVTKQEDLMREVNTFVKNL
...
CCDS54 EADHHMERMLELFEQNRDRILTPENRKHCP
210 220 230
>>CCDS54016.1 TK2 gene_id:7084|Hs108|chr16 (240 aa)
initn: 399 init1: 164 opt: 289 Z-score: 369.5 bits: 76.0 E(32554): 2.9e-14
Smith-Waterman score: 360; 33.2% identity (61.5% similar) in 226 aa overlap (29-253:21-213)
10 20 30 40 50
pF1KE3 MAAGRLFLSRLRAPFSSMAKSPLEGVSSSRGLHA-GRGPRRLSIEGNIAVGKSTFVKLLT
::: : : ::::.. . : . .
CCDS54 MLLWPLRGWAARALRCFGPGSRGSPASGPGPRRVQRR---AWPPDKEQEKEK
10 20 30 40
60 70 80 90 100 110
pF1KE3 KTYPEWHVATEPVATWQNIQAAGTQKACTAQSLGNLLDMMYREPARWSYTFQTFSFLSRL
:. : ::::. :.:... : : .::.. .::. :.::. :. :
CCDS54 KSV----VLTEPVSKWRNVRGH------------NPLGLMYHDASRWGLTLQTYVQLTML
50 60 70 80 90
120 130 140 150 160 170
pF1KE3 KVQLEPFPEKLLQARKPVQIFERSVYSDRYIFAKNLFENGSLSDIEWHIYQDWHSFLLWE
. .: :. . :...:::..: ::::..::...:.. .... . ..: ...: .
CCDS54 DRHTRP------QV-SSVRLMERSIHSARYIFVENLYRSGKMPEVDYVVLSEWFDWILRN
100 110 120 130 140
180 190 200 210 220 230
pF1KE3 FASRITLHGFIYLQASPQVCLKRLYQRAREEEKGIELAYLEQLHGQHEAWLIHKTTKLHF
. . : ..::...:..: .:: .: ::::: : : ::: .: :: :::. . :
CCDS54 MDVSVDL--IVYLRTNPETCYQRLKKRCREEEKVIPLEYLEAIHHLHEEWLIKGSL---F
150 160 170 180 190 200
240 250 260 270
pF1KE3 EALMNIPVLVLDVNDDFSEEVTKQEDLMREVNTFVKNL
: ::::....
CCDS54 P--MAAPVLVIEADHHMERMLELFEQNRDRILTPENRKHCP
210 220 230 240
>>CCDS54017.1 TK2 gene_id:7084|Hs108|chr16 (247 aa)
initn: 402 init1: 164 opt: 289 Z-score: 369.3 bits: 76.0 E(32554): 3e-14
Smith-Waterman score: 334; 31.0% identity (62.3% similar) in 239 aa overlap (22-253:5-220)
10 20 30 40 50
pF1KE3 MAAGRLFLSRLRAPFSSMAKSPLEGVSSSRGLHA-GRGPRRLSIEGNIAVGKSTFVKLLT
::.: .. :.:. : : : :. : : . ..
CCDS54 MLLWPLRGWAA-RALRCFGPGSR-----GSPASGPGPR-RVQR
10 20 30
60 70 80 90 100 110
pF1KE3 KTYP---EWHVATEPVATWQNIQAAGTQKACTAQSLGNLLD---MMYREPARWSYTFQTF
...: : . . : .. :.: . .: . ..: : .::.. .::. :.::.
CCDS54 RAWPPDKEQEKEKKSVICVEGNIASG-KTTCL-EFFSNATDVEGLMYHDASRWGLTLQTY
40 50 60 70 80 90
120 130 140 150 160 170
pF1KE3 SFLSRLKVQLEPFPEKLLQARKPVQIFERSVYSDRYIFAKNLFENGSLSDIEWHIYQDWH
:. : . .: :. . :...:::..: ::::..::...:.. .... . ..:
CCDS54 VQLTMLDRHTRP------QVSS-VRLMERSIHSARYIFVENLYRSGKMPEVDYVVLSEWF
100 110 120 130 140
180 190 200 210 220 230
pF1KE3 SFLLWEFASRITLHGFIYLQASPQVCLKRLYQRAREEEKGIELAYLEQLHGQHEAWLIHK
...: .. . : ..::...:..: .:: .: ::::: : : ::: .: :: :::.
CCDS54 DWILRNMDVSVDL--IVYLRTNPETCYQRLKKRCREEEKVIPLEYLEAIHHLHEEWLIKG
150 160 170 180 190 200
240 250 260 270
pF1KE3 TTKLHFEALMNIPVLVLDVNDDFSEEVTKQEDLMREVNTFVKNL
. : : ::::....
CCDS54 SL---FP--MAAPVLVIEADHHMERMLELFEQNRDRILTPENRKHCP
210 220 230 240
>>CCDS10805.2 TK2 gene_id:7084|Hs108|chr16 (265 aa)
initn: 422 init1: 164 opt: 289 Z-score: 368.8 bits: 76.0 E(32554): 3.2e-14
Smith-Waterman score: 404; 33.8% identity (66.7% similar) in 213 aa overlap (41-253:53-238)
20 30 40 50 60 70
pF1KE3 LRAPFSSMAKSPLEGVSSSRGLHAGRGPRRLSIEGNIAVGKSTFVKLLTKTYPEWHVATE
. .::::: ::.: ....... . .: ::
CCDS10 GSPASGPGPRRVQRRAWPPDKEQEKEKKSVICVEGNIASGKTTCLEFFSNA-TDVEVLTE
30 40 50 60 70 80
80 90 100 110 120 130
pF1KE3 PVATWQNIQAAGTQKACTAQSLGNLLDMMYREPARWSYTFQTFSFLSRLKVQLEPFPEKL
::. :.:... : : .::.. .::. :.::. :. : . .:
CCDS10 PVSKWRNVRGH------------NPLGLMYHDASRWGLTLQTYVQLTMLDRHTRP-----
90 100 110 120
140 150 160 170 180 190
pF1KE3 LQARKPVQIFERSVYSDRYIFAKNLFENGSLSDIEWHIYQDWHSFLLWEFASRITLHGFI
:. . :...:::..: ::::..::...:.. .... . ..: ...: .. . : ..
CCDS10 -QVSS-VRLMERSIHSARYIFVENLYRSGKMPEVDYVVLSEWFDWILRNMDVSVDL--IV
130 140 150 160 170 180
200 210 220 230 240 250
pF1KE3 YLQASPQVCLKRLYQRAREEEKGIELAYLEQLHGQHEAWLIHKTTKLHFEALMNIPVLVL
::...:..: .:: .: ::::: : : ::: .: :: :::. . : : ::::.
CCDS10 YLRTNPETCYQRLKKRCREEEKVIPLEYLEAIHHLHEEWLIKGSL---FP--MAAPVLVI
190 200 210 220 230
260 270
pF1KE3 DVNDDFSEEVTKQEDLMREVNTFVKNL
...
CCDS10 EADHHMERMLELFEQNRDRILTPENRKHCP
240 250 260
277 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 16:19:37 2016 done: Mon Nov 7 16:19:37 2016
Total Scan time: 2.030 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]