Result of FASTA (omim) for
pFN21AE3089
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3089, 257 aa
1>>>pF1KE3089 257 - 257 aa - 257 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5824+/-0.000285; mu= 13.9095+/- 0.018
mean_var=76.0741+/-15.119, 0's: 0 Z-trim(118.9): 12 B-trim: 1023 in 1/51
Lambda= 0.147047
statistics sampled from 32285 (32297) to 32285 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.756), E-opt: 0.2 (0.379), width: 16
Scan time: 6.670
The best scores are: opt bits E(85289)
NP_001025046 (OMIM: 610890) regulator of G-protein ( 257) 1727 375.1 6.9e-104
XP_005248559 (OMIM: 610890) PREDICTED: regulator o ( 227) 1379 301.2 1e-81
NP_001258819 (OMIM: 610890) regulator of G-protein ( 124) 826 183.8 1.3e-46
NP_001258820 (OMIM: 610890) regulator of G-protein ( 94) 478 109.9 1.7e-24
NP_997274 (OMIM: 607814,608415) regulator of G-pro ( 235) 163 43.3 0.00048
>>NP_001025046 (OMIM: 610890) regulator of G-protein sig (257 aa)
initn: 1727 init1: 1727 opt: 1727 Z-score: 1986.1 bits: 375.1 E(85289): 6.9e-104
Smith-Waterman score: 1727; 100.0% identity (100.0% similar) in 257 aa overlap (1-257:1-257)
10 20 30 40 50 60
pF1KE3 MSSAPNGRKKRPSRSTRSSIFQISKPPLQSGDWERRGSGSESAHKTQRALDDCKMLVQEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSSAPNGRKKRPSRSTRSSIFQISKPPLQSGDWERRGSGSESAHKTQRALDDCKMLVQEF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 NTQVALYRELVISIGDVSVSCPSLRAEMHKTRTKGCEMARQAHQKLAAISGPEDGEIHPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTQVALYRELVISIGDVSVSCPSLRAEMHKTRTKGCEMARQAHQKLAAISGPEDGEIHPE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 ICRLYIQLQCCLEMYTTEMLKSICLLGSLQFHRKGKEPGGGTKSLDCKIEESAETPALED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ICRLYIQLQCCLEMYTTEMLKSICLLGSLQFHRKGKEPGGGTKSLDCKIEESAETPALED
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 SSSSPVDSQQHSWQVSTDIENTERDMREMKNLLSKLRETMPLPLKNQDDSSLLNLTPYPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSSSPVDSQQHSWQVSTDIENTERDMREMKNLLSKLRETMPLPLKNQDDSSLLNLTPYPL
190 200 210 220 230 240
250
pF1KE3 VRRRKRRFFGLCCLISS
:::::::::::::::::
NP_001 VRRRKRRFFGLCCLISS
250
>>XP_005248559 (OMIM: 610890) PREDICTED: regulator of G- (227 aa)
initn: 1379 init1: 1379 opt: 1379 Z-score: 1588.0 bits: 301.2 E(85289): 1e-81
Smith-Waterman score: 1379; 98.1% identity (98.6% similar) in 210 aa overlap (1-210:1-210)
10 20 30 40 50 60
pF1KE3 MSSAPNGRKKRPSRSTRSSIFQISKPPLQSGDWERRGSGSESAHKTQRALDDCKMLVQEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSSAPNGRKKRPSRSTRSSIFQISKPPLQSGDWERRGSGSESAHKTQRALDDCKMLVQEF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 NTQVALYRELVISIGDVSVSCPSLRAEMHKTRTKGCEMARQAHQKLAAISGPEDGEIHPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NTQVALYRELVISIGDVSVSCPSLRAEMHKTRTKGCEMARQAHQKLAAISGPEDGEIHPE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 ICRLYIQLQCCLEMYTTEMLKSICLLGSLQFHRKGKEPGGGTKSLDCKIEESAETPALED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ICRLYIQLQCCLEMYTTEMLKSICLLGSLQFHRKGKEPGGGTKSLDCKIEESAETPALED
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 SSSSPVDSQQHSWQVSTDIENTERDMREMKNLLSKLRETMPLPLKNQDDSSLLNLTPYPL
:::::::::::::::::::::::: :. :
XP_005 SSSSPVDSQQHSWQVSTDIENTERHERNEKPFKQTQGNYAFTIEKSR
190 200 210 220
>>NP_001258819 (OMIM: 610890) regulator of G-protein sig (124 aa)
initn: 826 init1: 826 opt: 826 Z-score: 957.8 bits: 183.8 E(85289): 1.3e-46
Smith-Waterman score: 826; 100.0% identity (100.0% similar) in 124 aa overlap (134-257:1-124)
110 120 130 140 150 160
pF1KE3 QKLAAISGPEDGEIHPEICRLYIQLQCCLEMYTTEMLKSICLLGSLQFHRKGKEPGGGTK
::::::::::::::::::::::::::::::
NP_001 MYTTEMLKSICLLGSLQFHRKGKEPGGGTK
10 20 30
170 180 190 200 210 220
pF1KE3 SLDCKIEESAETPALEDSSSSPVDSQQHSWQVSTDIENTERDMREMKNLLSKLRETMPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLDCKIEESAETPALEDSSSSPVDSQQHSWQVSTDIENTERDMREMKNLLSKLRETMPLP
40 50 60 70 80 90
230 240 250
pF1KE3 LKNQDDSSLLNLTPYPLVRRRKRRFFGLCCLISS
::::::::::::::::::::::::::::::::::
NP_001 LKNQDDSSLLNLTPYPLVRRRKRRFFGLCCLISS
100 110 120
>>NP_001258820 (OMIM: 610890) regulator of G-protein sig (94 aa)
initn: 493 init1: 478 opt: 478 Z-score: 560.6 bits: 109.9 E(85289): 1.7e-24
Smith-Waterman score: 478; 94.8% identity (96.1% similar) in 77 aa overlap (134-210:1-77)
110 120 130 140 150 160
pF1KE3 QKLAAISGPEDGEIHPEICRLYIQLQCCLEMYTTEMLKSICLLGSLQFHRKGKEPGGGTK
::::::::::::::::::::::::::::::
NP_001 MYTTEMLKSICLLGSLQFHRKGKEPGGGTK
10 20 30
170 180 190 200 210 220
pF1KE3 SLDCKIEESAETPALEDSSSSPVDSQQHSWQVSTDIENTERDMREMKNLLSKLRETMPLP
::::::::::::::::::::::::::::::::::::::::: :. :
NP_001 SLDCKIEESAETPALEDSSSSPVDSQQHSWQVSTDIENTERHERNEKPFKQTQGNYAFTI
40 50 60 70 80 90
230 240 250
pF1KE3 LKNQDDSSLLNLTPYPLVRRRKRRFFGLCCLISS
NP_001 EKSR
>>NP_997274 (OMIM: 607814,608415) regulator of G-protein (235 aa)
initn: 99 init1: 58 opt: 163 Z-score: 193.6 bits: 43.3 E(85289): 0.00048
Smith-Waterman score: 163; 29.9% identity (67.3% similar) in 107 aa overlap (49-152:2-106)
20 30 40 50 60 70
pF1KE3 SIFQISKPPLQSGDWERRGSGSESAHKTQRALDDCKMLVQEFNTQVALYRELVISIGDVS
: ..:: :.. .: .: :..::...: :
NP_997 MAREECKALLDGLNKTTACYHHLVLTVGG-S
10 20 30
80 90 100 110 120 130
pF1KE3 VSCPSLRAEMHKTRTKGCEMARQAHQKLAAI---SGPEDGEIHPEICRLYIQLQCCLEMY
.. .:: :..::: :. :.: .. .:.:. : : . :. ::.. .. ::..
NP_997 ADSQNLRQELQKTRQKAQELAVSTCARLTAVLRDRGLAADE-RAEFERLWVAFSGCLDLL
40 50 60 70 80
140 150 160 170 180 190
pF1KE3 TTEMLKSICLLGSLQFHRKGKEPGGGTKSLDCKIEESAETPALEDSSSSPVDSQQHSWQV
..: ... : ... .:
NP_997 EADMRRALELGAAFPLHAPRRPLVRTGVAGASSGVAARALSTRSLRLEAEGDFDVADLRE
90 100 110 120 130 140
257 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 04:26:04 2016 done: Sun Nov 6 04:26:05 2016
Total Scan time: 6.670 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]