Result of FASTA (omim) for
pFN21AE3088
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3088, 215 aa
1>>>pF1KE3088 215 - 215 aa - 215 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.1716+/-0.0005; mu= -8.4931+/- 0.031
mean_var=274.5848+/-56.540, 0's: 0 Z-trim(115.9): 7 B-trim: 333 in 1/55
Lambda= 0.077399
statistics sampled from 26722 (26728) to 26722 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.653), E-opt: 0.2 (0.313), width: 16
Scan time: 6.510
The best scores are: opt bits E(85289)
NP_001165358 (OMIM: 608858) FGFR1 oncogene partner ( 215) 1337 162.1 6.1e-40
NP_001165359 (OMIM: 608858) FGFR1 oncogene partner ( 172) 831 105.6 5.2e-23
NP_056448 (OMIM: 608858) FGFR1 oncogene partner 2 ( 253) 831 105.7 7.1e-23
NP_079349 (OMIM: 611656) suppressor of IKBKE 1 iso ( 207) 667 87.3 2e-17
NP_001095866 (OMIM: 611656) suppressor of IKBKE 1 ( 211) 654 85.9 5.5e-17
>>NP_001165358 (OMIM: 608858) FGFR1 oncogene partner 2 i (215 aa)
initn: 1337 init1: 1337 opt: 1337 Z-score: 838.1 bits: 162.1 E(85289): 6.1e-40
Smith-Waterman score: 1337; 100.0% identity (100.0% similar) in 215 aa overlap (1-215:1-215)
10 20 30 40 50 60
pF1KE3 MSCTIEKALADAKALVERLRDHDDAAESLIEQTTALNKRVEAMKQYQEEIQELNEVARHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSCTIEKALADAKALVERLRDHDDAAESLIEQTTALNKRVEAMKQYQEEIQELNEVARHR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 PRSTLVMGIQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRSTLVMGIQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 GIIMKLKEQHSKELQAHVDQITEMAAVMRKAIEIDEQQGCKEQERIFQLEQENKGLREIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GIIMKLKEQHSKELQAHVDQITEMAAVMRKAIEIDEQQGCKEQERIFQLEQENKGLREIL
130 140 150 160 170 180
190 200 210
pF1KE3 QITRESFLNLRKDDASESTSLSALVTNSDLSLRKS
:::::::::::::::::::::::::::::::::::
NP_001 QITRESFLNLRKDDASESTSLSALVTNSDLSLRKS
190 200 210
>>NP_001165359 (OMIM: 608858) FGFR1 oncogene partner 2 i (172 aa)
initn: 828 init1: 828 opt: 831 Z-score: 534.1 bits: 105.6 E(85289): 5.2e-23
Smith-Waterman score: 831; 95.0% identity (97.9% similar) in 140 aa overlap (1-140:1-140)
10 20 30 40 50 60
pF1KE3 MSCTIEKALADAKALVERLRDHDDAAESLIEQTTALNKRVEAMKQYQEEIQELNEVARHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSCTIEKALADAKALVERLRDHDDAAESLIEQTTALNKRVEAMKQYQEEIQELNEVARHR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 PRSTLVMGIQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRSTLVMGIQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 GIIMKLKEQHSKELQAHVDQITEMAAVMRKAIEIDEQQGCKEQERIFQLEQENKGLREIL
:::::::::::: ..: ..
NP_001 GIIMKLKEQHSKIDMVHRNKSEGFFLDASRHILEAPQHGLERRHLEANQNVH
130 140 150 160 170
>>NP_056448 (OMIM: 608858) FGFR1 oncogene partner 2 isof (253 aa)
initn: 828 init1: 828 opt: 831 Z-score: 531.7 bits: 105.7 E(85289): 7.1e-23
Smith-Waterman score: 1218; 84.6% identity (84.6% similar) in 247 aa overlap (1-209:1-247)
10 20 30 40 50 60
pF1KE3 MSCTIEKALADAKALVERLRDHDDAAESLIEQTTALNKRVEAMKQYQEEIQELNEVARHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MSCTIEKALADAKALVERLRDHDDAAESLIEQTTALNKRVEAMKQYQEEIQELNEVARHR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 PRSTLVMGIQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 PRSTLVMGIQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDP
70 80 90 100 110 120
130 140
pF1KE3 GIIMKLKEQHSK--------------------------------------ELQAHVDQIT
:::::::::::: ::::::::::
NP_056 GIIMKLKEQHSKIDMVHRNKSEGFFLDASRHILEAPQHGLERRHLEANQNELQAHVDQIT
130 140 150 160 170 180
150 160 170 180 190 200
pF1KE3 EMAAVMRKAIEIDEQQGCKEQERIFQLEQENKGLREILQITRESFLNLRKDDASESTSLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 EMAAVMRKAIEIDEQQGCKEQERIFQLEQENKGLREILQITRESFLNLRKDDASESTSLS
190 200 210 220 230 240
210
pF1KE3 ALVTNSDLSLRKS
:::::::
NP_056 ALVTNSDLSLRKS
250
>>NP_079349 (OMIM: 611656) suppressor of IKBKE 1 isoform (207 aa)
initn: 740 init1: 441 opt: 667 Z-score: 434.0 bits: 87.3 E(85289): 2e-17
Smith-Waterman score: 667; 51.4% identity (81.2% similar) in 208 aa overlap (1-200:1-203)
10 20 30 40 50
pF1KE3 MSCTIEKALADAKALVERLRDHDDAAESLIEQTTALNKRVEAMK--------QYQEEIQE
::::::: :.:::.:.::::.:: :::::..:..::..:: ::. ::::. ..
NP_079 MSCTIEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQYQEDASD
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 LNEVARHRPRSTLVMGIQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLL
........:. : .::: :::.:::::.:: ::::::.::::::::::.::..:.
NP_079 MKDMSKYKPHILL----SQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLM
70 80 90 100 110
120 130 140 150 160 170
pF1KE3 MASKKDDPGIIMKLKEQHSKELQAHVDQITEMAAVMRKAIEIDEQQGCKEQERIFQLEQE
.:.: : ..: ...:: :.....:.: ::. :::::...:..: :: ::.. ::: :
NP_079 VAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELE
120 130 140 150 160 170
180 190 200 210
pF1KE3 NKGLREILQITRESFLNLRKDDASESTSLSALVTNSDLSLRKS
:: :::.:.:. :: :. ::... ...:
NP_079 NKELRELLSISSES-LQARKENSMDTASQAIK
180 190 200
>>NP_001095866 (OMIM: 611656) suppressor of IKBKE 1 isof (211 aa)
initn: 690 init1: 441 opt: 654 Z-score: 426.0 bits: 85.9 E(85289): 5.5e-17
Smith-Waterman score: 654; 50.0% identity (79.7% similar) in 212 aa overlap (1-200:1-207)
10 20 30 40
pF1KE3 MSCTIEKALADAKALVERLRDHDDAAESLIEQTTALNKRVEAMKQ------------YQE
::::::: :.:::.:.::::.:: :::::..:..::..:: ::.. :::
NP_001 MSCTIEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQE
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE3 EIQELNEVARHRPRSTLVMGIQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQM
. ..........:. : .::: :::.:::::.:: ::::::.::::::::::.::
NP_001 DASDMKDMSKYKPHILL----SQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQM
70 80 90 100 110
110 120 130 140 150 160
pF1KE3 FRLLMASKKDDPGIIMKLKEQHSKELQAHVDQITEMAAVMRKAIEIDEQQGCKEQERIFQ
..:..:.: : ..: ...:: :.....:.: ::. :::::...:..: :: ::.. :
NP_001 LQLMVAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQ
120 130 140 150 160 170
170 180 190 200 210
pF1KE3 LEQENKGLREILQITRESFLNLRKDDASESTSLSALVTNSDLSLRKS
:: ::: :::.:.:. :: :. ::... ...:
NP_001 LELENKELRELLSISSES-LQARKENSMDTASQAIK
180 190 200 210
215 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 05:14:32 2016 done: Sun Nov 6 05:14:33 2016
Total Scan time: 6.510 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]