Result of FASTA (omim) for
pFN21AE3086
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3086, 251 aa
1>>>pF1KE3086 251 - 251 aa - 251 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1649+/-0.000309; mu= 15.1674+/- 0.019
mean_var=66.5143+/-13.615, 0's: 0 Z-trim(117.3): 289 B-trim: 824 in 1/54
Lambda= 0.157259
statistics sampled from 28825 (29138) to 28825 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.721), E-opt: 0.2 (0.342), width: 16
Scan time: 7.270
The best scores are: opt bits E(85289)
NP_001691 (OMIM: 162815) azurocidin preproprotein ( 251) 1710 396.4 2.6e-110
XP_011526078 (OMIM: 130130,162800,202700) PREDICTE ( 267) 682 163.2 4.4e-40
XP_011526077 (OMIM: 130130,162800,202700) PREDICTE ( 267) 682 163.2 4.4e-40
NP_001963 (OMIM: 130130,162800,202700) neutrophil ( 267) 682 163.2 4.4e-40
NP_002768 (OMIM: 177020) myeloblastin precursor [H ( 256) 657 157.5 2.2e-38
XP_011526438 (OMIM: 177020) PREDICTED: myeloblasti ( 206) 517 125.7 6.6e-29
NP_001902 (OMIM: 116830) cathepsin G preproprotein ( 255) 441 108.5 1.2e-23
NP_219491 (OMIM: 116831) granzyme H isoform 1 prep ( 246) 434 106.9 3.6e-23
NP_005308 (OMIM: 600311) granzyme M isoform 1 prep ( 257) 434 106.9 3.7e-23
XP_011534801 (OMIM: 116830) PREDICTED: cathepsin G ( 269) 433 106.7 4.5e-23
NP_004908 (OMIM: 204700,603767) kallikrein-4 isofo ( 254) 415 102.6 7.2e-22
NP_001304264 (OMIM: 134350,613912) complement fact ( 260) 395 98.0 1.7e-20
NP_001919 (OMIM: 134350,613912) complement factor ( 253) 393 97.6 2.3e-20
NP_001827 (OMIM: 118938) chymase isoform 1 preprop ( 247) 389 96.7 4.2e-20
XP_011534985 (OMIM: 116831) PREDICTED: granzyme H ( 212) 382 95.0 1.1e-19
NP_005568 (OMIM: 152200) apolipoprotein(a) precurs (2040) 391 97.7 1.7e-19
NP_001012982 (OMIM: 602652) kallikrein-6 isoform A ( 244) 376 93.7 3.2e-19
NP_002765 (OMIM: 602652) kallikrein-6 isoform A pr ( 244) 376 93.7 3.2e-19
NP_009127 (OMIM: 605644) kallikrein-8 isoform 1 pr ( 260) 376 93.7 3.4e-19
NP_056411 (OMIM: 605505) kallikrein-13 precursor [ ( 277) 375 93.5 4.2e-19
NP_002095 (OMIM: 600784) granzyme K precursor [Hom ( 264) 371 92.6 7.6e-19
NP_002760 (OMIM: 167800,276000,614044) trypsin-1 p ( 247) 368 91.9 1.1e-18
NP_653088 (OMIM: 605644) kallikrein-8 isoform 2 pr ( 305) 368 92.0 1.4e-18
XP_011514713 (OMIM: 167800,276000,614044) PREDICTE ( 472) 368 92.1 1.9e-18
NP_001184027 (OMIM: 613578) trypsin-3 isoform 4 pr ( 240) 352 88.3 1.4e-17
NP_002762 (OMIM: 613578) trypsin-3 isoform 2 prepr ( 247) 352 88.3 1.4e-17
NP_006844 (OMIM: 604434) kallikrein-11 isoform 1 p ( 250) 352 88.3 1.4e-17
NP_001129504 (OMIM: 604434) kallikrein-11 isoform ( 250) 352 88.3 1.4e-17
NP_001184026 (OMIM: 613578) trypsin-3 isoform 3 pr ( 261) 352 88.3 1.5e-17
NP_659196 (OMIM: 604434) kallikrein-11 isoform 2 [ ( 282) 352 88.3 1.6e-17
NP_031369 (OMIM: 613578) trypsin-3 isoform 1 prepr ( 304) 352 88.3 1.7e-17
XP_011525005 (OMIM: 605643) PREDICTED: kallikrein- ( 293) 347 87.2 3.6e-17
NP_001070959 (OMIM: 605643) kallikrein-5 prepropro ( 293) 347 87.2 3.6e-17
NP_036559 (OMIM: 605643) kallikrein-5 preproprotei ( 293) 347 87.2 3.6e-17
NP_001070960 (OMIM: 605643) kallikrein-5 prepropro ( 293) 347 87.2 3.6e-17
XP_011525004 (OMIM: 605643) PREDICTED: kallikrein- ( 293) 347 87.2 3.6e-17
XP_011516267 (OMIM: 613578) PREDICTED: trypsin-3 i ( 333) 347 87.2 4e-17
NP_002761 (OMIM: 167800,601564) trypsin-2 isoform ( 247) 338 85.1 1.3e-16
NP_036447 (OMIM: 605504) kallikrein-9 precursor [H ( 250) 338 85.1 1.3e-16
NP_071329 (OMIM: 606135) kallikrein-14 preproprote ( 267) 335 84.4 2.2e-16
NP_001298111 (OMIM: 606135) kallikrein-14 prepropr ( 267) 335 84.4 2.2e-16
NP_001245280 (OMIM: 600311) granzyme M isoform 2 [ ( 218) 329 83.0 4.8e-16
NP_001275930 (OMIM: 206200,609862) transmembrane p ( 802) 334 84.5 6.3e-16
NP_705837 (OMIM: 206200,609862) transmembrane prot ( 811) 334 84.5 6.3e-16
NP_004122 (OMIM: 123910) granzyme B isoform 1 prep ( 247) 324 81.9 1.2e-15
NP_001332940 (OMIM: 123910) granzyme B isoform 2 [ ( 235) 318 80.5 2.9e-15
NP_006135 (OMIM: 140050) granzyme A precursor [Hom ( 262) 317 80.3 3.7e-15
NP_005037 (OMIM: 604438) kallikrein-7 isoform 1 pr ( 253) 311 79.0 9.1e-15
NP_644806 (OMIM: 604438) kallikrein-7 isoform 1 pr ( 253) 311 79.0 9.1e-15
NP_001182058 (OMIM: 613517,613858) serine protease ( 603) 312 79.4 1.6e-14
>>NP_001691 (OMIM: 162815) azurocidin preproprotein [Hom (251 aa)
initn: 1710 init1: 1710 opt: 1710 Z-score: 2101.5 bits: 396.4 E(85289): 2.6e-110
Smith-Waterman score: 1710; 100.0% identity (100.0% similar) in 251 aa overlap (1-251:1-251)
10 20 30 40 50 60
pF1KE3 MTRLTVLALLAGLLASSRAGSSPLLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTRLTVLALLAGLLASSRAGSSPLLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHAR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FVMTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FVMTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 LDREANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDREANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 RPNNVCTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGRGPDFFTRVALFRDWID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPNNVCTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGRGPDFFTRVALFRDWID
190 200 210 220 230 240
250
pF1KE3 GVLNNPGPGPA
:::::::::::
NP_001 GVLNNPGPGPA
250
>>XP_011526078 (OMIM: 130130,162800,202700) PREDICTED: n (267 aa)
initn: 416 init1: 246 opt: 682 Z-score: 840.6 bits: 163.2 E(85289): 4.4e-40
Smith-Waterman score: 682; 43.9% identity (69.4% similar) in 255 aa overlap (3-250:6-257)
10 20 30 40 50
pF1KE3 MTRLTVLALLAGLLASSRAGSSPLL-DIVGGRKARPRQFPFLASIQNQGRHFCGGAL
::. : .:: .: . :.. : .:::::.:::. .::..:.: .: ::::..:
XP_011 MTLGRRLACL-FLACVLPALLLGGTALASEIVGGRRARPHAWPFMVSLQLRGGHFCGATL
10 20 30 40 50
60 70 80 90 100 110
pF1KE3 IHARFVMTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDL
: :::.:: : . : . :::::..: ::: .::.:... . :::::: . :::.
XP_011 IAPNFVMSAAHCVANVNVRAVRVVLGAHNLSRRE-PTRQVFAVQRIFENGYDPVNLLNDI
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE3 MLLQLDREANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTP
..:::. :.....: . :: :. . :..: . ::: . .. . .::::.
XP_011 VILQLNGSATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVT
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE3 EDQCRPNNVCTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGRG--PDFFTRVAL
. :: .:::: : :..:.: ::.:.::::.:: ::.::: : :. : :: :. ::
XP_011 -SLCRRSNVCTLVRGRQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQ
180 190 200 210 220 230
240 250
pF1KE3 FRDWIDGVL----NNPGPGPA
: .:::... .:: : :
XP_011 FVNWIDSIIQRSEDNPCPHPRDPDPASRTH
240 250 260
>>XP_011526077 (OMIM: 130130,162800,202700) PREDICTED: n (267 aa)
initn: 416 init1: 246 opt: 682 Z-score: 840.6 bits: 163.2 E(85289): 4.4e-40
Smith-Waterman score: 682; 43.9% identity (69.4% similar) in 255 aa overlap (3-250:6-257)
10 20 30 40 50
pF1KE3 MTRLTVLALLAGLLASSRAGSSPLL-DIVGGRKARPRQFPFLASIQNQGRHFCGGAL
::. : .:: .: . :.. : .:::::.:::. .::..:.: .: ::::..:
XP_011 MTLGRRLACL-FLACVLPALLLGGTALASEIVGGRRARPHAWPFMVSLQLRGGHFCGATL
10 20 30 40 50
60 70 80 90 100 110
pF1KE3 IHARFVMTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDL
: :::.:: : . : . :::::..: ::: .::.:... . :::::: . :::.
XP_011 IAPNFVMSAAHCVANVNVRAVRVVLGAHNLSRRE-PTRQVFAVQRIFENGYDPVNLLNDI
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE3 MLLQLDREANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTP
..:::. :.....: . :: :. . :..: . ::: . .. . .::::.
XP_011 VILQLNGSATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVT
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE3 EDQCRPNNVCTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGRG--PDFFTRVAL
. :: .:::: : :..:.: ::.:.::::.:: ::.::: : :. : :: :. ::
XP_011 -SLCRRSNVCTLVRGRQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQ
180 190 200 210 220 230
240 250
pF1KE3 FRDWIDGVL----NNPGPGPA
: .:::... .:: : :
XP_011 FVNWIDSIIQRSEDNPCPHPRDPDPASRTH
240 250 260
>>NP_001963 (OMIM: 130130,162800,202700) neutrophil elas (267 aa)
initn: 416 init1: 246 opt: 682 Z-score: 840.6 bits: 163.2 E(85289): 4.4e-40
Smith-Waterman score: 682; 43.9% identity (69.4% similar) in 255 aa overlap (3-250:6-257)
10 20 30 40 50
pF1KE3 MTRLTVLALLAGLLASSRAGSSPLL-DIVGGRKARPRQFPFLASIQNQGRHFCGGAL
::. : .:: .: . :.. : .:::::.:::. .::..:.: .: ::::..:
NP_001 MTLGRRLACL-FLACVLPALLLGGTALASEIVGGRRARPHAWPFMVSLQLRGGHFCGATL
10 20 30 40 50
60 70 80 90 100 110
pF1KE3 IHARFVMTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDL
: :::.:: : . : . :::::..: ::: .::.:... . :::::: . :::.
NP_001 IAPNFVMSAAHCVANVNVRAVRVVLGAHNLSRRE-PTRQVFAVQRIFENGYDPVNLLNDI
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE3 MLLQLDREANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTP
..:::. :.....: . :: :. . :..: . ::: . .. . .::::.
NP_001 VILQLNGSATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVT
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE3 EDQCRPNNVCTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGRG--PDFFTRVAL
. :: .:::: : :..:.: ::.:.::::.:: ::.::: : :. : :: :. ::
NP_001 -SLCRRSNVCTLVRGRQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQ
180 190 200 210 220 230
240 250
pF1KE3 FRDWIDGVL----NNPGPGPA
: .:::... .:: : :
NP_001 FVNWIDSIIQRSEDNPCPHPRDPDPASRTH
240 250 260
>>NP_002768 (OMIM: 177020) myeloblastin precursor [Homo (256 aa)
initn: 450 init1: 201 opt: 657 Z-score: 810.2 bits: 157.5 E(85289): 2.2e-38
Smith-Waterman score: 657; 43.6% identity (71.0% similar) in 241 aa overlap (8-243:9-247)
10 20 30 40 50
pF1KE3 MTRLTVLALLAGLLASSRAGSSPLLDIVGGRKARPRQFPFLASIQ---NQGRHFCGGAL
:: . ::: .:.. .::::..:.:.. :..::.: : : :::::.:
NP_002 MAHRPPSPALASVLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 IHARFVMTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDL
:: ::.::: :... . .:::::...: .: ..: ::.... :.:: ...:::.
NP_002 IHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRTQE-PTQQHFSVAQVFLNNYDAENKLNDV
70 80 90 100 110
120 130 140 150 160 170
pF1KE3 MLLQLDREANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTP
.:.::. :::..::. . :: :. : ::.: . ::: . .. . .::::.
NP_002 LLIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE3 EDQCRPNNVCTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGRG--PDFFTRVAL
:::.:.:: : :..::: ::.: ::.:.:. .:. :: . :. :::::::::
NP_002 F-FCRPHNICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVAL
180 190 200 210 220 230
240 250
pF1KE3 FRDWIDGVLNNPGPGPA
. ::: ..:
NP_002 YVDWIRSTLRRVEAKGRP
240 250
>>XP_011526438 (OMIM: 177020) PREDICTED: myeloblastin is (206 aa)
initn: 393 init1: 201 opt: 517 Z-score: 640.0 bits: 125.7 E(85289): 6.6e-29
Smith-Waterman score: 517; 42.5% identity (70.5% similar) in 200 aa overlap (8-204:9-206)
10 20 30 40 50
pF1KE3 MTRLTVLALLAGLLASSRAGSSPLLDIVGGRKARPRQFPFLASIQ---NQGRHFCGGAL
:: . ::: .:.. .::::..:.:.. :..::.: : : :::::.:
XP_011 MAHRPPSPALASVLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 IHARFVMTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDL
:: ::.::: :... . .:::::...: .: ..: ::.... :.:: ...:::.
XP_011 IHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRTQE-PTQQHFSVAQVFLNNYDAENKLNDV
70 80 90 100 110
120 130 140 150 160 170
pF1KE3 MLLQLDREANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTP
.:.::. :::..::. . :: :. : ::.: . ::: . .. . .::::.
XP_011 LLIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE3 EDQCRPNNVCTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGRGPDFFTRVALFR
:::.:.:: : :..::: ::.: :
XP_011 F-FCRPHNICTFVPRRKAGICFGDSGGP
180 190 200
>>NP_001902 (OMIM: 116830) cathepsin G preproprotein [Ho (255 aa)
initn: 436 init1: 167 opt: 441 Z-score: 545.4 bits: 108.5 E(85289): 1.2e-23
Smith-Waterman score: 441; 35.5% identity (62.9% similar) in 248 aa overlap (6-239:4-238)
10 20 30 40 50
pF1KE3 MTRLTVLALLAGLLAS-SRAGSSPLLDIVGGRKARPRQFPFLASIQNQ---GRHFCGGAL
.: ::: :: . ..:: .:.:::..::.. :..: .: : :. ::: :
NP_001 MQPLLLLLAFLLPTGAEAG-----EIIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFL
10 20 30 40 50
60 70 80 90 100 110
pF1KE3 IHARFVMTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDL
.. ::.::: :. :. .:.:::....::: ... . .. . :. . ::.
NP_001 VREDFVLTAAHCWGSNI----NVTLGAHNIQRRENTQQHITARRAIRHPQYNQRTIQNDI
60 70 80 90 100
120 130 140 150 160 170
pF1KE3 MLLQLDREANLTSSVTILPLPLQNATVEAGTRCQVAGWG--SQRSGGRLSRFPRFVNVTV
:::::.:.. . .:. . :: . .. :: : ::::: :.: : . : :.. :
NP_001 MLLQLSRRVRRNRNVNPVALPRAQEGLRPGTLCTVAGWGRVSMRRG---TDTLREVQLRV
110 120 130 140 150 160
180 190 200 210 220
pF1KE3 TPEDQC-------RPN-NVCTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGRGP
. :: : ..:.: .: . .::.: ::.:...:::..:.. . : :
NP_001 QRDRQCLRIFGSYDPRRQICVGDRRERKAAFKGDSGGPLLCNNVAHGIVSYGKSS-GVPP
170 180 190 200 210 220
230 240 250
pF1KE3 DFFTRVALFRDWIDGVLNNPGPGPA
. ::::. : ::
NP_001 EVFTRVSSFLPWIRTTMRSFKLLDQMETPL
230 240 250
>>NP_219491 (OMIM: 116831) granzyme H isoform 1 prepropr (246 aa)
initn: 371 init1: 193 opt: 434 Z-score: 537.1 bits: 106.9 E(85289): 3.6e-23
Smith-Waterman score: 434; 35.0% identity (65.0% similar) in 246 aa overlap (7-239:5-239)
10 20 30 40 50
pF1KE3 MTRLTVLALLAGLLASSRAGSSPLLDIVGGRKARPRQFPFLASIQ---NQGRHFCGGALI
: ::: ::. . ::. .:.::..:.:.. :..: .: ...:. ::: :.
NP_219 MQPFLLLLAFLLTPG-AGTE---EIIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILV
10 20 30 40 50
60 70 80 90 100 110
pF1KE3 HARFVMTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISS-MSENGYDPQQNLNDL
. ::.::: : :. ... :.:::......:: ..: . .. . . .:.:.. ::.
NP_219 RKDFVLTAAHC---QGSSIN-VTLGAHNIKEQER-TQQFIPVKRPIPHPAYNPKNFSNDI
60 70 80 90 100
120 130 140 150 160 170
pF1KE3 MLLQLDREANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTP
:::::.:.:. :..: : :: ..: :. : :.::::: : . :. . : .::
NP_219 MLLQLERKAKWTTAVRPLRLPSSKAQVKPGQLCSVAGWG-YVSMSTLATTLQEVLLTVQK
110 120 130 140 150 160
180 190 200 210 220
pF1KE3 EDQC---------RPNNVCTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGRGPD
. :: : ...:.: . .::.: ::::. .:.:. :.. . : :
NP_219 DCQCERLFHGNYSRATEICVGDPKKTQTGFKGDSGGPLVCKDVAQGILSYG-NKKGTPPG
170 180 190 200 210 220
230 240 250
pF1KE3 FFTRVALFRDWIDGVLNNPGPGPA
. .:. : ::
NP_219 VYIKVSHFLPWIKRTMKRL
230 240
>>NP_005308 (OMIM: 600311) granzyme M isoform 1 prepropr (257 aa)
initn: 445 init1: 191 opt: 434 Z-score: 536.8 bits: 106.9 E(85289): 3.7e-23
Smith-Waterman score: 465; 37.2% identity (60.9% similar) in 253 aa overlap (6-242:5-252)
10 20 30 40 50 60
pF1KE3 MTRLTVLALLAGLLASSRAGSSPLLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHAR
: .::. :.. .::: .:.:::.. :.. :..::.: .: :.:::.:.: .
NP_005 MEACVSSLLVLALGALSVGSSFGTQIIGGREVIPHSRPYMASLQRNGSHLCGGVLVHPK
10 20 30 40 50
70 80 90 100 110
pF1KE3 FVMTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSI-SSMSENGYDPQQNL-NDLML
.:.::: :. .: . .::: . : . :: : ..... : : : ::: :
NP_005 WVLTAAHCL-AQRMAQLRLVLGLHTLD----SPGLTFHIKAAIQHPRYKPVPALENDLAL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE3 LQLDREANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPED
:::: ... . .. : :: . .: :::::..:::: ..:::::: : ... :
NP_005 LQLDGKVKPSRTIRPLALPSKRQVVAAGTRCSMAGWGLTHQGGRLSRVLRELDLQVLDTR
120 130 140 150 160 170
180 190 200 210 220
pF1KE3 QCR----------PNNVCTGVLTRRGGICNGDGGTPLVC-EG-LAHGVASFSLGPCGR--
.: :. :: .. .. . :.::.: :::: .: . :: ::: :
NP_005 MCNNSRFWNGSLSPSMVCLAADSKDQAPCKGDSGGPLVCGKGRVLAGVLSFSSRVCTDIF
180 190 200 210 220 230
230 240 250
pF1KE3 GPDFFTRVALFRDWIDGVLNNPGPGPA
: : :: . .:: :
NP_005 KPPVATAVAPYVSWIRKVTGRSA
240 250
>>XP_011534801 (OMIM: 116830) PREDICTED: cathepsin G iso (269 aa)
initn: 436 init1: 167 opt: 433 Z-score: 535.3 bits: 106.7 E(85289): 4.5e-23
Smith-Waterman score: 437; 34.6% identity (61.9% similar) in 257 aa overlap (6-239:4-252)
10 20 30 40
pF1KE3 MTRLTVLALLAGLLAS-SRAGSSPLL---------DIVGGRKARPRQFPFLASIQNQ---
.: ::: :: . ..:::. . .:.:::..::.. :..: .: :
XP_011 MQPLLLLLAFLLPTGAEAGSASIELSAKCFLPGEIIGGRESRPHSRPYMAYLQIQSPA
10 20 30 40 50
50 60 70 80 90 100
pF1KE3 GRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGY
:. ::: :.. ::.::: :. :. .:.:::....::: ... . .. . :
XP_011 GQSRCGGFLVREDFVLTAAHCWGSNI----NVTLGAHNIQRRENTQQHITARRAIRHPQY
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE3 DPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAGTRCQVAGWG--SQRSGGRLSR
. . ::.:::::.:.. . .:. . :: . .. :: : ::::: :.: : .
XP_011 NQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEGLRPGTLCTVAGWGRVSMRRG---TD
120 130 140 150 160 170
170 180 190 200 210
pF1KE3 FPRFVNVTVTPEDQC-------RPN-NVCTGVLTRRGGICNGDGGTPLVCEGLAHGVASF
: :.. : . :: : ..:.: .: . .::.: ::.:...:::..:.
XP_011 TLREVQLRVQRDRQCLRIFGSYDPRRQICVGDRRERKAAFKGDSGGPLLCNNVAHGIVSY
180 190 200 210 220 230
220 230 240 250
pF1KE3 SLGPCGRGPDFFTRVALFRDWIDGVLNNPGPGPA
. . : :. ::::. : ::
XP_011 GKSS-GVPPEVFTRVSSFLPWIRTTMRSFKLLDQMETPL
240 250 260
251 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 05:15:04 2016 done: Sun Nov 6 05:15:06 2016
Total Scan time: 7.270 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]