Result of FASTA (omim) for
pFN21AE3067
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3067, 222 aa
1>>>pF1KE3067 222 - 222 aa - 222 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.0738+/-0.000293; mu= 12.7980+/- 0.018
mean_var=128.8813+/-25.268, 0's: 0 Z-trim(121.8): 95 B-trim: 134 in 1/57
Lambda= 0.112974
statistics sampled from 38837 (38939) to 38837 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.793), E-opt: 0.2 (0.457), width: 16
Scan time: 6.950
The best scores are: opt bits E(85289)
NP_055316 (OMIM: 610309) ubiquitin-conjugating enz ( 222) 1478 251.0 1.2e-66
XP_011525054 (OMIM: 610309) PREDICTED: ubiquitin-c ( 162) 773 136.0 3.6e-32
NP_003328 (OMIM: 179095) ubiquitin-conjugating enz ( 152) 376 71.2 1e-12
NP_003330 (OMIM: 602962) ubiquitin-conjugating enz ( 147) 374 70.9 1.3e-12
NP_871621 (OMIM: 602963) ubiquitin-conjugating enz ( 148) 373 70.7 1.4e-12
NP_003339 (OMIM: 603679) ubiquitin-conjugating enz ( 152) 372 70.6 1.6e-12
NP_003327 (OMIM: 300860,312180) ubiquitin-conjugat ( 152) 370 70.3 2e-12
NP_871617 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 364 69.3 3.9e-12
NP_871618 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 364 69.3 3.9e-12
NP_871619 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 364 69.3 3.9e-12
NP_871616 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 364 69.3 3.9e-12
NP_003331 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 364 69.3 3.9e-12
NP_871615 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 364 69.3 3.9e-12
NP_871620 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 364 69.3 3.9e-12
NP_871622 (OMIM: 602963) ubiquitin-conjugating enz ( 149) 360 68.6 6.2e-12
XP_016865309 (OMIM: 602962) PREDICTED: ubiquitin-c ( 173) 360 68.7 6.9e-12
NP_003329 (OMIM: 602961) ubiquitin-conjugating enz ( 147) 356 68.0 9.7e-12
NP_862821 (OMIM: 602962) ubiquitin-conjugating enz ( 118) 321 62.2 4.4e-10
NP_005330 (OMIM: 602846) ubiquitin-conjugating enz ( 200) 320 62.2 7e-10
NP_001269090 (OMIM: 300860,312180) ubiquitin-conju ( 119) 315 61.2 8.6e-10
XP_016864073 (OMIM: 602963) PREDICTED: ubiquitin-c ( 118) 313 60.8 1.1e-09
NP_001287724 (OMIM: 602963) ubiquitin-conjugating ( 118) 313 60.8 1.1e-09
NP_054895 (OMIM: 610538,616435) ubiquitin-conjugat ( 197) 314 61.2 1.4e-09
NP_919236 (OMIM: 601661) SUMO-conjugating enzyme U ( 158) 310 60.5 1.8e-09
NP_003336 (OMIM: 601661) SUMO-conjugating enzyme U ( 158) 310 60.5 1.8e-09
NP_919237 (OMIM: 601661) SUMO-conjugating enzyme U ( 158) 310 60.5 1.8e-09
XP_016879129 (OMIM: 601661) PREDICTED: SUMO-conjug ( 158) 310 60.5 1.8e-09
NP_919235 (OMIM: 601661) SUMO-conjugating enzyme U ( 158) 310 60.5 1.8e-09
XP_005246301 (OMIM: 604151) PREDICTED: ubiquitin-c ( 207) 310 60.6 2.2e-09
NP_872619 (OMIM: 604151) ubiquitin-conjugating enz ( 207) 310 60.6 2.2e-09
NP_006348 (OMIM: 604151) ubiquitin-conjugating enz ( 207) 310 60.6 2.2e-09
NP_001265484 (OMIM: 604151) ubiquitin-conjugating ( 207) 310 60.6 2.2e-09
NP_001265483 (OMIM: 604151) ubiquitin-conjugating ( 207) 310 60.6 2.2e-09
NP_689866 (OMIM: 602163) ubiquitin-conjugating enz ( 201) 309 60.4 2.4e-09
XP_005265489 (OMIM: 602163) PREDICTED: ubiquitin-c ( 201) 309 60.4 2.4e-09
NP_003332 (OMIM: 602916) ubiquitin-conjugating enz ( 193) 304 59.6 4.2e-09
NP_001189405 (OMIM: 602916) ubiquitin-conjugating ( 160) 301 59.0 5.1e-09
XP_005265490 (OMIM: 602163) PREDICTED: ubiquitin-c ( 189) 295 58.1 1.1e-08
XP_011520946 (OMIM: 601661) PREDICTED: SUMO-conjug ( 184) 294 58.0 1.2e-08
XP_005255597 (OMIM: 601661) PREDICTED: SUMO-conjug ( 184) 294 58.0 1.2e-08
XP_011520947 (OMIM: 601661) PREDICTED: SUMO-conjug ( 184) 294 58.0 1.2e-08
XP_005255598 (OMIM: 601661) PREDICTED: SUMO-conjug ( 184) 294 58.0 1.2e-08
XP_016872098 (OMIM: 602961) PREDICTED: ubiquitin-c ( 110) 288 56.7 1.7e-08
XP_005265488 (OMIM: 602916) PREDICTED: ubiquitin-c ( 167) 288 56.9 2.3e-08
NP_001104582 (OMIM: 602846) ubiquitin-conjugating ( 157) 287 56.7 2.5e-08
NP_008950 (OMIM: 605574) ubiquitin-conjugating enz ( 179) 277 55.2 8.4e-08
NP_001191809 (OMIM: 602961) ubiquitin-conjugating ( 109) 272 54.1 1e-07
NP_003960 (OMIM: 603173) NEDD8-conjugating enzyme ( 183) 271 54.2 1.7e-07
NP_861517 (OMIM: 605574) ubiquitin-conjugating enz ( 140) 269 53.8 1.7e-07
NP_003335 (OMIM: 601082) ubiquitin-conjugating enz ( 183) 266 53.4 2.9e-07
>>NP_055316 (OMIM: 610309) ubiquitin-conjugating enzyme (222 aa)
initn: 1478 init1: 1478 opt: 1478 Z-score: 1317.8 bits: 251.0 E(85289): 1.2e-66
Smith-Waterman score: 1478; 100.0% identity (100.0% similar) in 222 aa overlap (1-222:1-222)
10 20 30 40 50 60
pF1KE3 MNSNVENLPPHIIRLVYKEVTTLTADPPDGIKVFPNEEDLTDLQVTIEGPEGTPYAGGLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MNSNVENLPPHIIRLVYKEVTTLTADPPDGIKVFPNEEDLTDLQVTIEGPEGTPYAGGLF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 RMKLLLGKDFPASPPKGYFLTKIFHPNVGANGEICVNVLKRDWTAELGIRHVLLTIKCLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RMKLLLGKDFPASPPKGYFLTKIFHPNVGANGEICVNVLKRDWTAELGIRHVLLTIKCLL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 IHPNPESALNEEAGRLLLENYEEYAARARLLTEIHGGAGGPSGRAEAGRALASGTEASST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 IHPNPESALNEEAGRLLLENYEEYAARARLLTEIHGGAGGPSGRAEAGRALASGTEASST
130 140 150 160 170 180
190 200 210 220
pF1KE3 DPGAPGGPGGAEGPMAKKHAGERDKKLAAKKKTDKKRALRRL
::::::::::::::::::::::::::::::::::::::::::
NP_055 DPGAPGGPGGAEGPMAKKHAGERDKKLAAKKKTDKKRALRRL
190 200 210 220
>>XP_011525054 (OMIM: 610309) PREDICTED: ubiquitin-conju (162 aa)
initn: 773 init1: 773 opt: 773 Z-score: 698.5 bits: 136.0 E(85289): 3.6e-32
Smith-Waterman score: 773; 100.0% identity (100.0% similar) in 114 aa overlap (1-114:1-114)
10 20 30 40 50 60
pF1KE3 MNSNVENLPPHIIRLVYKEVTTLTADPPDGIKVFPNEEDLTDLQVTIEGPEGTPYAGGLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MNSNVENLPPHIIRLVYKEVTTLTADPPDGIKVFPNEEDLTDLQVTIEGPEGTPYAGGLF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 RMKLLLGKDFPASPPKGYFLTKIFHPNVGANGEICVNVLKRDWTAELGIRHVLLTIKCLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RMKLLLGKDFPASPPKGYFLTKIFHPNVGANGEICVNVLKRDWTAELGIRHVLLLSWKDK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 IHPNPESALNEEAGRLLLENYEEYAARARLLTEIHGGAGGPSGRAEAGRALASGTEASST
XP_011 QCQTQDTQVLLRSAQEHLTMQRVVSLYCRMVFLFSLFFKKQG
130 140 150 160
>>NP_003328 (OMIM: 179095) ubiquitin-conjugating enzyme (152 aa)
initn: 384 init1: 366 opt: 376 Z-score: 349.2 bits: 71.2 E(85289): 1e-12
Smith-Waterman score: 376; 36.4% identity (68.6% similar) in 140 aa overlap (14-153:7-146)
10 20 30 40 50 60
pF1KE3 MNSNVENLPPHIIRLVYKEVTTLTADPPDGIKVFPNEEDLTDLQVTIEGPEGTPYAGGLF
: .... : ::: :.. :.:... . ...: ::::::. : :
NP_003 MSTPARRRLMRDFKRLQEDPPVGVSGAPSENNIMQWNAVIFGPEGTPFEDGTF
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 RMKLLLGKDFPASPPKGYFLTKIFHPNVGANGEICVNVLKRDWTAELGIRHVLLTIKCLL
.. . .....: .:: ::.:.::::: :.: ::...:. :. . .: .:. ::
NP_003 KLVIEFSEEYPNKPPTVRFLSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSLL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE3 IHPNPESALNEEAGRLLLENYEEYAARARLLTEIHGGAGGPSGRAEAGRALASGTEASST
.:::.: : .:..: :: .:: :. ..:
NP_003 DEPNPNSPANSQAAQLYQENKREYEKRVSAIVEQSWNDS
120 130 140 150
190 200 210 220
pF1KE3 DPGAPGGPGGAEGPMAKKHAGERDKKLAAKKKTDKKRALRRL
>>NP_003330 (OMIM: 602962) ubiquitin-conjugating enzyme (147 aa)
initn: 372 init1: 372 opt: 374 Z-score: 347.6 bits: 70.9 E(85289): 1.3e-12
Smith-Waterman score: 374; 38.3% identity (66.7% similar) in 141 aa overlap (13-153:3-143)
10 20 30 40 50 60
pF1KE3 MNSNVENLPPHIIRLVYKEVTTLTADPPDGIKVFPNEEDLTDLQVTIEGPEGTPYAGGLF
.. ..::.. :. ::: .. : .:. :.:: ::. .:: ::.:
NP_003 MALKRIHKELNDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVF
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 RMKLLLGKDFPASPPKGYFLTKIFHPNVGANGEICVNVLKRDWTAELGIRHVLLTIKCLL
. . . :.: .::: : :.:.:::...:: ::...:. .:. : : .:::.: ::
NP_003 FLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE3 IHPNPESALNEEAGRLLLENYEEYAARARLLTEIHGGAGGPSGRAEAGRALASGTEASST
:::.. : : .:. . :.: :: :.
NP_003 CDPNPDDPLVPEIARIYKTDREKYNRIAREWTQKYAM
120 130 140
190 200 210 220
pF1KE3 DPGAPGGPGGAEGPMAKKHAGERDKKLAAKKKTDKKRALRRL
>>NP_871621 (OMIM: 602963) ubiquitin-conjugating enzyme (148 aa)
initn: 373 init1: 373 opt: 373 Z-score: 346.7 bits: 70.7 E(85289): 1.4e-12
Smith-Waterman score: 373; 38.3% identity (66.0% similar) in 141 aa overlap (13-153:3-143)
10 20 30 40 50 60
pF1KE3 MNSNVENLPPHIIRLVYKEVTTLTADPPDGIKVFPNEEDLTDLQVTIEGPEGTPYAGGLF
.. . ::.. :. ::: .. : .:. :.:: ::. .:: ::.:
NP_871 MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVF
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 RMKLLLGKDFPASPPKGYFLTKIFHPNVGANGEICVNVLKRDWTAELGIRHVLLTIKCLL
. . . :.: .::: : :.:.:::...:: ::...:. .:. : : .:::.: ::
NP_871 FLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE3 IHPNPESALNEEAGRLLLENYEEYAARARLLTEIHGGAGGPSGRAEAGRALASGTEASST
:::.. : : .:. . ..: :: ::
NP_871 CDPNPDDPLVPEIARIYKTDRDKYNRLAREWTEKYAML
120 130 140
190 200 210 220
pF1KE3 DPGAPGGPGGAEGPMAKKHAGERDKKLAAKKKTDKKRALRRL
>>NP_003339 (OMIM: 603679) ubiquitin-conjugating enzyme (152 aa)
initn: 379 init1: 365 opt: 372 Z-score: 345.6 bits: 70.6 E(85289): 1.6e-12
Smith-Waterman score: 372; 38.7% identity (66.9% similar) in 142 aa overlap (14-155:6-147)
10 20 30 40 50 60
pF1KE3 MNSNVENLPPHIIRLVYKEVTTLTADPPDGIKVFPNEEDLTDLQVTIEGPEGTPYAGGLF
: . ::. : :.: :::. :.: . ..:.: ::. .:. :: :
NP_003 MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTF
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 RMKLLLGKDFPASPPKGYFLTKIFHPNVGANGEICVNVLKRDWTAELGIRHVLLTIKCLL
...:.: ...: . :: :.:::.:::: :.::...:: :. : :: :::.:. ::
NP_003 KLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE3 IHPNPESALNEEAGRLLLENYEEYAARARLLTEIHGGAGGPSGRAEAGRALASGTEASST
:::.. : ..... : . :: :...
NP_003 SAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNI
120 130 140 150
190 200 210 220
pF1KE3 DPGAPGGPGGAEGPMAKKHAGERDKKLAAKKKTDKKRALRRL
>>NP_003327 (OMIM: 300860,312180) ubiquitin-conjugating (152 aa)
initn: 378 init1: 360 opt: 370 Z-score: 343.9 bits: 70.3 E(85289): 2e-12
Smith-Waterman score: 370; 35.7% identity (67.1% similar) in 140 aa overlap (14-153:7-146)
10 20 30 40 50 60
pF1KE3 MNSNVENLPPHIIRLVYKEVTTLTADPPDGIKVFPNEEDLTDLQVTIEGPEGTPYAGGLF
: .... : ::: :.. :.:... ...: ::::::. : :
NP_003 MSTPARRRLMRDFKRLQEDPPAGVSGAPSENNIMVWNAVIFGPEGTPFEDGTF
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 RMKLLLGKDFPASPPKGYFLTKIFHPNVGANGEICVNVLKRDWTAELGIRHVLLTIKCLL
.. . . ...: .:: :..:.::::: :.: ::...:. :. . .: .:. ::
NP_003 KLTIEFTEEYPNKPPTVRFVSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSLL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE3 IHPNPESALNEEAGRLLLENYEEYAARARLLTEIHGGAGGPSGRAEAGRALASGTEASST
.:::.: : .:..: :: .:: :. ..:
NP_003 DEPNPNSPANSQAAQLYQENKREYEKRVSAIVEQSWRDC
120 130 140 150
190 200 210 220
pF1KE3 DPGAPGGPGGAEGPMAKKHAGERDKKLAAKKKTDKKRALRRL
>>NP_871617 (OMIM: 602963) ubiquitin-conjugating enzyme (147 aa)
initn: 391 init1: 350 opt: 364 Z-score: 338.8 bits: 69.3 E(85289): 3.9e-12
Smith-Waterman score: 364; 36.9% identity (66.0% similar) in 141 aa overlap (13-153:3-143)
10 20 30 40 50 60
pF1KE3 MNSNVENLPPHIIRLVYKEVTTLTADPPDGIKVFPNEEDLTDLQVTIEGPEGTPYAGGLF
.. . ::.. :. ::: .. : .:. :.:: ::. .:: ::.:
NP_871 MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVF
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 RMKLLLGKDFPASPPKGYFLTKIFHPNVGANGEICVNVLKRDWTAELGIRHVLLTIKCLL
. . . :.: .::: : :.:.:::...:: ::...:. .:. : : .:::.: ::
NP_871 FLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE3 IHPNPESALNEEAGRLLLENYEEYAARARLLTEIHGGAGGPSGRAEAGRALASGTEASST
:::.. : : .:. . ..: .: :.
NP_871 CDPNPDDPLVPEIARIYKTDRDKYNRISREWTQKYAM
120 130 140
190 200 210 220
pF1KE3 DPGAPGGPGGAEGPMAKKHAGERDKKLAAKKKTDKKRALRRL
>>NP_871618 (OMIM: 602963) ubiquitin-conjugating enzyme (147 aa)
initn: 391 init1: 350 opt: 364 Z-score: 338.8 bits: 69.3 E(85289): 3.9e-12
Smith-Waterman score: 364; 36.9% identity (66.0% similar) in 141 aa overlap (13-153:3-143)
10 20 30 40 50 60
pF1KE3 MNSNVENLPPHIIRLVYKEVTTLTADPPDGIKVFPNEEDLTDLQVTIEGPEGTPYAGGLF
.. . ::.. :. ::: .. : .:. :.:: ::. .:: ::.:
NP_871 MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVF
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 RMKLLLGKDFPASPPKGYFLTKIFHPNVGANGEICVNVLKRDWTAELGIRHVLLTIKCLL
. . . :.: .::: : :.:.:::...:: ::...:. .:. : : .:::.: ::
NP_871 FLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE3 IHPNPESALNEEAGRLLLENYEEYAARARLLTEIHGGAGGPSGRAEAGRALASGTEASST
:::.. : : .:. . ..: .: :.
NP_871 CDPNPDDPLVPEIARIYKTDRDKYNRISREWTQKYAM
120 130 140
190 200 210 220
pF1KE3 DPGAPGGPGGAEGPMAKKHAGERDKKLAAKKKTDKKRALRRL
>>NP_871619 (OMIM: 602963) ubiquitin-conjugating enzyme (147 aa)
initn: 391 init1: 350 opt: 364 Z-score: 338.8 bits: 69.3 E(85289): 3.9e-12
Smith-Waterman score: 364; 36.9% identity (66.0% similar) in 141 aa overlap (13-153:3-143)
10 20 30 40 50 60
pF1KE3 MNSNVENLPPHIIRLVYKEVTTLTADPPDGIKVFPNEEDLTDLQVTIEGPEGTPYAGGLF
.. . ::.. :. ::: .. : .:. :.:: ::. .:: ::.:
NP_871 MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVF
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 RMKLLLGKDFPASPPKGYFLTKIFHPNVGANGEICVNVLKRDWTAELGIRHVLLTIKCLL
. . . :.: .::: : :.:.:::...:: ::...:. .:. : : .:::.: ::
NP_871 FLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE3 IHPNPESALNEEAGRLLLENYEEYAARARLLTEIHGGAGGPSGRAEAGRALASGTEASST
:::.. : : .:. . ..: .: :.
NP_871 CDPNPDDPLVPEIARIYKTDRDKYNRISREWTQKYAM
120 130 140
190 200 210 220
pF1KE3 DPGAPGGPGGAEGPMAKKHAGERDKKLAAKKKTDKKRALRRL
222 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 05:20:45 2016 done: Sun Nov 6 05:20:46 2016
Total Scan time: 6.950 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]