Result of FASTA (omim) for
pFN21AE3064
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3064, 219 aa
1>>>pF1KE3064 219 - 219 aa - 219 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2552+/-0.000288; mu= 16.2763+/- 0.018
mean_var=80.0215+/-15.846, 0's: 0 Z-trim(119.6): 16 B-trim: 350 in 1/53
Lambda= 0.143374
statistics sampled from 33877 (33893) to 33877 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.76), E-opt: 0.2 (0.397), width: 16
Scan time: 6.390
The best scores are: opt bits E(85289)
XP_005248294 (OMIM: 608773) PREDICTED: tubulin pol ( 219) 1430 304.3 1e-82
NP_008961 (OMIM: 608773) tubulin polymerization-pr ( 219) 1430 304.3 1e-82
XP_016864483 (OMIM: 608773) PREDICTED: tubulin pol ( 219) 1430 304.3 1e-82
XP_016864482 (OMIM: 608773) PREDICTED: tubulin pol ( 286) 1430 304.4 1.3e-82
NP_057224 (OMIM: 616957) tubulin polymerization-pr ( 176) 777 169.1 4e-42
NP_057048 (OMIM: 616957) tubulin polymerization-pr ( 176) 777 169.1 4e-42
XP_016876455 (OMIM: 616956) PREDICTED: tubulin pol ( 170) 683 149.7 2.8e-36
NP_776245 (OMIM: 616956) tubulin polymerization-pr ( 170) 683 149.7 2.8e-36
XP_005267381 (OMIM: 616956) PREDICTED: tubulin pol ( 170) 683 149.7 2.8e-36
XP_011534718 (OMIM: 616956) PREDICTED: tubulin pol ( 157) 435 98.3 7.3e-21
XP_011534722 (OMIM: 616956) PREDICTED: tubulin pol ( 124) 413 93.7 1.4e-19
XP_011534719 (OMIM: 616956) PREDICTED: tubulin pol ( 124) 413 93.7 1.4e-19
XP_011534720 (OMIM: 616956) PREDICTED: tubulin pol ( 124) 413 93.7 1.4e-19
>>XP_005248294 (OMIM: 608773) PREDICTED: tubulin polymer (219 aa)
initn: 1430 init1: 1430 opt: 1430 Z-score: 1605.9 bits: 304.3 E(85289): 1e-82
Smith-Waterman score: 1430; 100.0% identity (100.0% similar) in 219 aa overlap (1-219:1-219)
10 20 30 40 50 60
pF1KE3 MADKAKPAKAANRTPPKSPGDPSKDRAAKRLSLESEGAGEGAAASPELSALEEAFRRFAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MADKAKPAKAANRTPPKSPGDPSKDRAAKRLSLESEGAGEGAAASPELSALEEAFRRFAV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 HGDARATGREMHGKNWSKLCKDCQVIDGRNVTVTDVDIVFSKIKGKSCRTITFEQFQEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HGDARATGREMHGKNWSKLCKDCQVIDGRNVTVTDVDIVFSKIKGKSCRTITFEQFQEAL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 EELAKKRFKDKSSEEAVREVHRLIEGKAPIISGVTKAISSPTVSRLTDTTKFTGSHKERF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EELAKKRFKDKSSEEAVREVHRLIEGKAPIISGVTKAISSPTVSRLTDTTKFTGSHKERF
130 140 150 160 170 180
190 200 210
pF1KE3 DPSGKGKGKAGRVDLVDESGYVSGYKHAGTYDQKVQGGK
:::::::::::::::::::::::::::::::::::::::
XP_005 DPSGKGKGKAGRVDLVDESGYVSGYKHAGTYDQKVQGGK
190 200 210
>>NP_008961 (OMIM: 608773) tubulin polymerization-promot (219 aa)
initn: 1430 init1: 1430 opt: 1430 Z-score: 1605.9 bits: 304.3 E(85289): 1e-82
Smith-Waterman score: 1430; 100.0% identity (100.0% similar) in 219 aa overlap (1-219:1-219)
10 20 30 40 50 60
pF1KE3 MADKAKPAKAANRTPPKSPGDPSKDRAAKRLSLESEGAGEGAAASPELSALEEAFRRFAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 MADKAKPAKAANRTPPKSPGDPSKDRAAKRLSLESEGAGEGAAASPELSALEEAFRRFAV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 HGDARATGREMHGKNWSKLCKDCQVIDGRNVTVTDVDIVFSKIKGKSCRTITFEQFQEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 HGDARATGREMHGKNWSKLCKDCQVIDGRNVTVTDVDIVFSKIKGKSCRTITFEQFQEAL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 EELAKKRFKDKSSEEAVREVHRLIEGKAPIISGVTKAISSPTVSRLTDTTKFTGSHKERF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 EELAKKRFKDKSSEEAVREVHRLIEGKAPIISGVTKAISSPTVSRLTDTTKFTGSHKERF
130 140 150 160 170 180
190 200 210
pF1KE3 DPSGKGKGKAGRVDLVDESGYVSGYKHAGTYDQKVQGGK
:::::::::::::::::::::::::::::::::::::::
NP_008 DPSGKGKGKAGRVDLVDESGYVSGYKHAGTYDQKVQGGK
190 200 210
>>XP_016864483 (OMIM: 608773) PREDICTED: tubulin polymer (219 aa)
initn: 1430 init1: 1430 opt: 1430 Z-score: 1605.9 bits: 304.3 E(85289): 1e-82
Smith-Waterman score: 1430; 100.0% identity (100.0% similar) in 219 aa overlap (1-219:1-219)
10 20 30 40 50 60
pF1KE3 MADKAKPAKAANRTPPKSPGDPSKDRAAKRLSLESEGAGEGAAASPELSALEEAFRRFAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MADKAKPAKAANRTPPKSPGDPSKDRAAKRLSLESEGAGEGAAASPELSALEEAFRRFAV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 HGDARATGREMHGKNWSKLCKDCQVIDGRNVTVTDVDIVFSKIKGKSCRTITFEQFQEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HGDARATGREMHGKNWSKLCKDCQVIDGRNVTVTDVDIVFSKIKGKSCRTITFEQFQEAL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 EELAKKRFKDKSSEEAVREVHRLIEGKAPIISGVTKAISSPTVSRLTDTTKFTGSHKERF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EELAKKRFKDKSSEEAVREVHRLIEGKAPIISGVTKAISSPTVSRLTDTTKFTGSHKERF
130 140 150 160 170 180
190 200 210
pF1KE3 DPSGKGKGKAGRVDLVDESGYVSGYKHAGTYDQKVQGGK
:::::::::::::::::::::::::::::::::::::::
XP_016 DPSGKGKGKAGRVDLVDESGYVSGYKHAGTYDQKVQGGK
190 200 210
>>XP_016864482 (OMIM: 608773) PREDICTED: tubulin polymer (286 aa)
initn: 1430 init1: 1430 opt: 1430 Z-score: 1604.3 bits: 304.4 E(85289): 1.3e-82
Smith-Waterman score: 1430; 100.0% identity (100.0% similar) in 219 aa overlap (1-219:68-286)
10 20 30
pF1KE3 MADKAKPAKAANRTPPKSPGDPSKDRAAKR
::::::::::::::::::::::::::::::
XP_016 HAAQPPPGSCPCILRWVGICIFGAFQGKGNMADKAKPAKAANRTPPKSPGDPSKDRAAKR
40 50 60 70 80 90
40 50 60 70 80 90
pF1KE3 LSLESEGAGEGAAASPELSALEEAFRRFAVHGDARATGREMHGKNWSKLCKDCQVIDGRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSLESEGAGEGAAASPELSALEEAFRRFAVHGDARATGREMHGKNWSKLCKDCQVIDGRN
100 110 120 130 140 150
100 110 120 130 140 150
pF1KE3 VTVTDVDIVFSKIKGKSCRTITFEQFQEALEELAKKRFKDKSSEEAVREVHRLIEGKAPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTVTDVDIVFSKIKGKSCRTITFEQFQEALEELAKKRFKDKSSEEAVREVHRLIEGKAPI
160 170 180 190 200 210
160 170 180 190 200 210
pF1KE3 ISGVTKAISSPTVSRLTDTTKFTGSHKERFDPSGKGKGKAGRVDLVDESGYVSGYKHAGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISGVTKAISSPTVSRLTDTTKFTGSHKERFDPSGKGKGKAGRVDLVDESGYVSGYKHAGT
220 230 240 250 260 270
pF1KE3 YDQKVQGGK
:::::::::
XP_016 YDQKVQGGK
280
>>NP_057224 (OMIM: 616957) tubulin polymerization-promot (176 aa)
initn: 798 init1: 777 opt: 777 Z-score: 877.2 bits: 169.1 E(85289): 4e-42
Smith-Waterman score: 777; 64.9% identity (87.4% similar) in 174 aa overlap (43-216:2-175)
20 30 40 50 60 70
pF1KE3 RTPPKSPGDPSKDRAAKRLSLESEGAGEGAAASPELSALEEAFRRFAVHGDARATGREMH
::: ....:::.::.::.::: .:.:.::.
NP_057 MAASTDMAGLEESFRKFAIHGDPKASGQEMN
10 20 30
80 90 100 110 120 130
pF1KE3 GKNWSKLCKDCQVIDGRNVTVTDVDIVFSKIKGKSCRTITFEQFQEALEELAKKRFKDKS
::::.::::::.: ::..:: :::::::::.:::: :.:..:.:..:::::: :::: ::
NP_057 GKNWAKLCKDCKVADGKSVTGTDVDIVFSKVKGKSARVINYEEFKKALEELATKRFKGKS
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE3 SEEAVREVHRLIEGKAPIISGVTKAISSPTVSRLTDTTKFTGSHKERFDPSGKGKGKAGR
.::: . .:. :: : ::::: .. .:.:::::...::::::::: :::::: :::
NP_057 KEEAFDAICQLVAGKEPANVGVTKAKTGGAVDRLTDTSRYTGSHKERFDESGKGKGIAGR
100 110 120 130 140 150
200 210
pF1KE3 VDLVDESGYVSGYKHAGTYDQKVQGGK
:..:.:::::.::.::::: ::.
NP_057 QDILDDSGYVSAYKNAGTYDAKVKK
160 170
>>NP_057048 (OMIM: 616957) tubulin polymerization-promot (176 aa)
initn: 798 init1: 777 opt: 777 Z-score: 877.2 bits: 169.1 E(85289): 4e-42
Smith-Waterman score: 777; 64.9% identity (87.4% similar) in 174 aa overlap (43-216:2-175)
20 30 40 50 60 70
pF1KE3 RTPPKSPGDPSKDRAAKRLSLESEGAGEGAAASPELSALEEAFRRFAVHGDARATGREMH
::: ....:::.::.::.::: .:.:.::.
NP_057 MAASTDMAGLEESFRKFAIHGDPKASGQEMN
10 20 30
80 90 100 110 120 130
pF1KE3 GKNWSKLCKDCQVIDGRNVTVTDVDIVFSKIKGKSCRTITFEQFQEALEELAKKRFKDKS
::::.::::::.: ::..:: :::::::::.:::: :.:..:.:..:::::: :::: ::
NP_057 GKNWAKLCKDCKVADGKSVTGTDVDIVFSKVKGKSARVINYEEFKKALEELATKRFKGKS
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE3 SEEAVREVHRLIEGKAPIISGVTKAISSPTVSRLTDTTKFTGSHKERFDPSGKGKGKAGR
.::: . .:. :: : ::::: .. .:.:::::...::::::::: :::::: :::
NP_057 KEEAFDAICQLVAGKEPANVGVTKAKTGGAVDRLTDTSRYTGSHKERFDESGKGKGIAGR
100 110 120 130 140 150
200 210
pF1KE3 VDLVDESGYVSGYKHAGTYDQKVQGGK
:..:.:::::.::.::::: ::.
NP_057 QDILDDSGYVSAYKNAGTYDAKVKK
160 170
>>XP_016876455 (OMIM: 616956) PREDICTED: tubulin polymer (170 aa)
initn: 710 init1: 666 opt: 683 Z-score: 772.3 bits: 149.7 E(85289): 2.8e-36
Smith-Waterman score: 683; 58.3% identity (87.5% similar) in 168 aa overlap (49-216:3-170)
20 30 40 50 60 70
pF1KE3 PGDPSKDRAAKRLSLESEGAGEGAAASPELSALEEAFRRFAVHGDARATGREMHGKNWSK
: :..:.:::. :.. ..: ::..::.::
XP_016 MASEAEKTFHRFAAFGESSSSGTEMNNKNFSK
10 20 30
80 90 100 110 120 130
pF1KE3 LCKDCQVIDGRNVTVTDVDIVFSKIKGKSCRTITFEQFQEALEELAKKRFKDKSSEEAVR
::::: ..::..:: :::::::::.:.:. :::::.::.::..::..:::: :: .:...
XP_016 LCKDCGIMDGKTVTSTDVDIVFSKVKAKNARTITFQQFKEAVKELGQKRFKGKSPDEVLE
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE3 EVHRLIEGKAPIISGVTKAISSPTVSRLTDTTKFTGSHKERFDPSGKGKGKAGRVDLVDE
... :.::: : .:.::: . .:.:::::.:.::.:::::: :::::: ::: ...:.
XP_016 NIYGLMEGKDPATTGATKATTVGAVDRLTDTSKYTGTHKERFDESGKGKGIAGREEMTDN
100 110 120 130 140 150
200 210
pF1KE3 SGYVSGYKHAGTYDQKVQGGK
.::::::: .::::.:..
XP_016 TGYVSGYKGSGTYDKKTK
160 170
>>NP_776245 (OMIM: 616956) tubulin polymerization-promot (170 aa)
initn: 710 init1: 666 opt: 683 Z-score: 772.3 bits: 149.7 E(85289): 2.8e-36
Smith-Waterman score: 683; 58.3% identity (87.5% similar) in 168 aa overlap (49-216:3-170)
20 30 40 50 60 70
pF1KE3 PGDPSKDRAAKRLSLESEGAGEGAAASPELSALEEAFRRFAVHGDARATGREMHGKNWSK
: :..:.:::. :.. ..: ::..::.::
NP_776 MASEAEKTFHRFAAFGESSSSGTEMNNKNFSK
10 20 30
80 90 100 110 120 130
pF1KE3 LCKDCQVIDGRNVTVTDVDIVFSKIKGKSCRTITFEQFQEALEELAKKRFKDKSSEEAVR
::::: ..::..:: :::::::::.:.:. :::::.::.::..::..:::: :: .:...
NP_776 LCKDCGIMDGKTVTSTDVDIVFSKVKAKNARTITFQQFKEAVKELGQKRFKGKSPDEVLE
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE3 EVHRLIEGKAPIISGVTKAISSPTVSRLTDTTKFTGSHKERFDPSGKGKGKAGRVDLVDE
... :.::: : .:.::: . .:.:::::.:.::.:::::: :::::: ::: ...:.
NP_776 NIYGLMEGKDPATTGATKATTVGAVDRLTDTSKYTGTHKERFDESGKGKGIAGREEMTDN
100 110 120 130 140 150
200 210
pF1KE3 SGYVSGYKHAGTYDQKVQGGK
.::::::: .::::.:..
NP_776 TGYVSGYKGSGTYDKKTK
160 170
>>XP_005267381 (OMIM: 616956) PREDICTED: tubulin polymer (170 aa)
initn: 710 init1: 666 opt: 683 Z-score: 772.3 bits: 149.7 E(85289): 2.8e-36
Smith-Waterman score: 683; 58.3% identity (87.5% similar) in 168 aa overlap (49-216:3-170)
20 30 40 50 60 70
pF1KE3 PGDPSKDRAAKRLSLESEGAGEGAAASPELSALEEAFRRFAVHGDARATGREMHGKNWSK
: :..:.:::. :.. ..: ::..::.::
XP_005 MASEAEKTFHRFAAFGESSSSGTEMNNKNFSK
10 20 30
80 90 100 110 120 130
pF1KE3 LCKDCQVIDGRNVTVTDVDIVFSKIKGKSCRTITFEQFQEALEELAKKRFKDKSSEEAVR
::::: ..::..:: :::::::::.:.:. :::::.::.::..::..:::: :: .:...
XP_005 LCKDCGIMDGKTVTSTDVDIVFSKVKAKNARTITFQQFKEAVKELGQKRFKGKSPDEVLE
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE3 EVHRLIEGKAPIISGVTKAISSPTVSRLTDTTKFTGSHKERFDPSGKGKGKAGRVDLVDE
... :.::: : .:.::: . .:.:::::.:.::.:::::: :::::: ::: ...:.
XP_005 NIYGLMEGKDPATTGATKATTVGAVDRLTDTSKYTGTHKERFDESGKGKGIAGREEMTDN
100 110 120 130 140 150
200 210
pF1KE3 SGYVSGYKHAGTYDQKVQGGK
.::::::: .::::.:..
XP_005 TGYVSGYKGSGTYDKKTK
160 170
>>XP_011534718 (OMIM: 616956) PREDICTED: tubulin polymer (157 aa)
initn: 421 init1: 421 opt: 435 Z-score: 495.6 bits: 98.3 E(85289): 7.3e-21
Smith-Waterman score: 435; 47.5% identity (78.7% similar) in 141 aa overlap (49-182:3-143)
20 30 40 50 60 70
pF1KE3 PGDPSKDRAAKRLSLESEGAGEGAAASPELSALEEAFRRFAVHGDARATGREMHGKNWSK
: :..:.:::. :.. ..: ::..::.::
XP_011 MASEAEKTFHRFAAFGESSSSGTEMNNKNFSK
10 20 30
80 90 100 110 120 130
pF1KE3 LCKDCQVIDGRNVTVTDVDIVFSKIKGKSCRTITFEQFQEALEELAKKRFKDKSSEEAVR
::::: ..::..:: :::::::::.:.:. :::::.::.::..::..:::: :: .:...
XP_011 LCKDCGIMDGKTVTSTDVDIVFSKVKAKNARTITFQQFKEAVKELGQKRFKGKSPDEVLE
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE3 EVHRLIEGKAPIISGVTKAISS-------PTVSRLTDTTKFTGSHKERFDPSGKGKGKAG
... :.::: : .:.: .:: :: ::... .. .... ::
XP_011 NIYGLMEGKDPATTGATWMLSSRLDSTHTPTPVRLNSNISLIQLQEKKCDPFFRLKVCNS
100 110 120 130 140 150
200 210
pF1KE3 RVDLVDESGYVSGYKHAGTYDQKVQGGK
XP_011 LFLIG
219 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 04:52:20 2016 done: Sun Nov 6 04:52:21 2016
Total Scan time: 6.390 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]