Result of FASTA (omim) for
pFN21AE3057
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3057, 212 aa
1>>>pF1KE3057 212 - 212 aa - 212 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4579+/-0.000372; mu= 12.2852+/- 0.023
mean_var=61.7221+/-12.614, 0's: 0 Z-trim(112.5): 12 B-trim: 916 in 1/50
Lambda= 0.163250
statistics sampled from 21498 (21507) to 21498 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.646), E-opt: 0.2 (0.252), width: 16
Scan time: 5.920
The best scores are: opt bits E(85289)
NP_036277 (OMIM: 188345) thymidylate kinase isofor ( 212) 1390 335.9 3e-92
NP_001307834 (OMIM: 188345) thymidylate kinase iso ( 251) 881 216.0 4.3e-56
NP_001307833 (OMIM: 188345) thymidylate kinase iso ( 193) 698 172.9 3.2e-43
NP_001307831 (OMIM: 188345) thymidylate kinase iso ( 169) 696 172.4 3.9e-43
NP_001158503 (OMIM: 188345) thymidylate kinase iso ( 188) 695 172.2 5.1e-43
NP_001307832 (OMIM: 188345) thymidylate kinase iso ( 113) 509 128.3 5e-30
>>NP_036277 (OMIM: 188345) thymidylate kinase isoform 1 (212 aa)
initn: 1390 init1: 1390 opt: 1390 Z-score: 1777.2 bits: 335.9 E(85289): 3e-92
Smith-Waterman score: 1390; 100.0% identity (100.0% similar) in 212 aa overlap (1-212:1-212)
10 20 30 40 50 60
pF1KE3 MAARRGALIVLEGVDRAGKSTQSRKLVEALCAAGHRAELLRFPERSTEIGKLLSSYLQKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MAARRGALIVLEGVDRAGKSTQSRKLVEALCAAGHRAELLRFPERSTEIGKLLSSYLQKK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 SDVEDHSVHLLFSANRWEQVPLIKEKLSQGVTLVVDRYAFSGVAFTGAKENFSLDWCKQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 SDVEDHSVHLLFSANRWEQVPLIKEKLSQGVTLVVDRYAFSGVAFTGAKENFSLDWCKQP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 DVGLPKPDLVLFLQLQLADAAKRGAFGHERYENGAFQERALRCFHQLMKDTTLNWKMVDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 DVGLPKPDLVLFLQLQLADAAKRGAFGHERYENGAFQERALRCFHQLMKDTTLNWKMVDA
130 140 150 160 170 180
190 200 210
pF1KE3 SKSIEAVHEDIRVLSEDAIRTATEKPLGELWK
::::::::::::::::::::::::::::::::
NP_036 SKSIEAVHEDIRVLSEDAIRTATEKPLGELWK
190 200 210
>>NP_001307834 (OMIM: 188345) thymidylate kinase isoform (251 aa)
initn: 1376 init1: 881 opt: 881 Z-score: 1128.1 bits: 216.0 E(85289): 4.3e-56
Smith-Waterman score: 1258; 84.0% identity (84.0% similar) in 244 aa overlap (8-212:8-251)
10 20 30 40 50 60
pF1KE3 MAARRGALIVLEGVDRAGKSTQSRKLVEALCAAGHRAELLRFPERSTEIGKLLSSYLQKK
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAARRGALIVLEGVDRAGKSTQSRKLVEALCAAGHRAELLRFPERSTEIGKLLSSYLQKK
10 20 30 40 50 60
70 80
pF1KE3 SDVEDHSVHLLFSANRWEQV---------------------------------------P
:::::::::::::::::::: :
NP_001 SDVEDHSVHLLFSANRWEQVFILVAQTGVQWGDLGSLQPTPRRFKRFSCLSLSSSCDHRP
70 80 90 100 110 120
90 100 110 120 130 140
pF1KE3 LIKEKLSQGVTLVVDRYAFSGVAFTGAKENFSLDWCKQPDVGLPKPDLVLFLQLQLADAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LIKEKLSQGVTLVVDRYAFSGVAFTGAKENFSLDWCKQPDVGLPKPDLVLFLQLQLADAA
130 140 150 160 170 180
150 160 170 180 190 200
pF1KE3 KRGAFGHERYENGAFQERALRCFHQLMKDTTLNWKMVDASKSIEAVHEDIRVLSEDAIRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRGAFGHERYENGAFQERALRCFHQLMKDTTLNWKMVDASKSIEAVHEDIRVLSEDAIRT
190 200 210 220 230 240
210
pF1KE3 ATEKPLGELWK
:::::::::::
NP_001 ATEKPLGELWK
250
>>NP_001307833 (OMIM: 188345) thymidylate kinase isoform (193 aa)
initn: 1193 init1: 698 opt: 698 Z-score: 897.0 bits: 172.9 E(85289): 3.2e-43
Smith-Waterman score: 1164; 87.7% identity (88.7% similar) in 212 aa overlap (1-212:1-193)
10 20 30 40 50 60
pF1KE3 MAARRGALIVLEGVDRAGKSTQSRKLVEALCAAGHRAELLRFPERSTEIGKLLSSYLQKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAARRGALIVLEGVDRAGKSTQSRKLVEALCAAGHRAELLRFPERSTEIGKLLSSYLQKK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 SDVEDHSVHLLFSANRWEQVPLIKEKLSQGVTLVVDRYAFSGVAFTGAKENFSLDWCKQP
:::::::::::::::::::: .. :: :: ::::::::::
NP_001 SDVEDHSVHLLFSANRWEQV-----RFPLHSTLNVD--------------NFSLDWCKQP
70 80 90 100
130 140 150 160 170 180
pF1KE3 DVGLPKPDLVLFLQLQLADAAKRGAFGHERYENGAFQERALRCFHQLMKDTTLNWKMVDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVGLPKPDLVLFLQLQLADAAKRGAFGHERYENGAFQERALRCFHQLMKDTTLNWKMVDA
110 120 130 140 150 160
190 200 210
pF1KE3 SKSIEAVHEDIRVLSEDAIRTATEKPLGELWK
::::::::::::::::::::::::::::::::
NP_001 SKSIEAVHEDIRVLSEDAIRTATEKPLGELWK
170 180 190
>>NP_001307831 (OMIM: 188345) thymidylate kinase isoform (169 aa)
initn: 1101 init1: 696 opt: 696 Z-score: 895.4 bits: 172.4 E(85289): 3.9e-43
Smith-Waterman score: 1019; 79.7% identity (79.7% similar) in 212 aa overlap (1-212:1-169)
10 20 30 40 50 60
pF1KE3 MAARRGALIVLEGVDRAGKSTQSRKLVEALCAAGHRAELLRFPERSTEIGKLLSSYLQKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAARRGALIVLEGVDRAGKSTQSRKLVEALCAAGHRAELLRFPERSTEIGKLLSSYLQKK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 SDVEDHSVHLLFSANRWEQVPLIKEKLSQGVTLVVDRYAFSGVAFTGAKENFSLDWCKQP
::::::: ::::::::::
NP_001 SDVEDHS-------------------------------------------NFSLDWCKQP
70
130 140 150 160 170 180
pF1KE3 DVGLPKPDLVLFLQLQLADAAKRGAFGHERYENGAFQERALRCFHQLMKDTTLNWKMVDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVGLPKPDLVLFLQLQLADAAKRGAFGHERYENGAFQERALRCFHQLMKDTTLNWKMVDA
80 90 100 110 120 130
190 200 210
pF1KE3 SKSIEAVHEDIRVLSEDAIRTATEKPLGELWK
::::::::::::::::::::::::::::::::
NP_001 SKSIEAVHEDIRVLSEDAIRTATEKPLGELWK
140 150 160
>>NP_001158503 (OMIM: 188345) thymidylate kinase isoform (188 aa)
initn: 711 init1: 694 opt: 695 Z-score: 893.4 bits: 172.2 E(85289): 5.1e-43
Smith-Waterman score: 1153; 88.7% identity (88.7% similar) in 212 aa overlap (1-212:1-188)
10 20 30 40 50 60
pF1KE3 MAARRGALIVLEGVDRAGKSTQSRKLVEALCAAGHRAELLRFPERSTEIGKLLSSYLQKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAARRGALIVLEGVDRAGKSTQSRKLVEALCAAGHRAELLRFPERSTEIGKLLSSYLQKK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 SDVEDHSVHLLFSANRWEQVPLIKEKLSQGVTLVVDRYAFSGVAFTGAKENFSLDWCKQP
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SDVEDHSVHLLFSANRWEQVPLIKEKLSQGVTLVVDRYAFSGVAFTGAKE----------
70 80 90 100 110
130 140 150 160 170 180
pF1KE3 DVGLPKPDLVLFLQLQLADAAKRGAFGHERYENGAFQERALRCFHQLMKDTTLNWKMVDA
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 --------------LQLADAAKRGAFGHERYENGAFQERALRCFHQLMKDTTLNWKMVDA
120 130 140 150
190 200 210
pF1KE3 SKSIEAVHEDIRVLSEDAIRTATEKPLGELWK
::::::::::::::::::::::::::::::::
NP_001 SKSIEAVHEDIRVLSEDAIRTATEKPLGELWK
160 170 180
>>NP_001307832 (OMIM: 188345) thymidylate kinase isoform (113 aa)
initn: 509 init1: 509 opt: 509 Z-score: 660.1 bits: 128.3 E(85289): 5e-30
Smith-Waterman score: 509; 100.0% identity (100.0% similar) in 80 aa overlap (1-80:1-80)
10 20 30 40 50 60
pF1KE3 MAARRGALIVLEGVDRAGKSTQSRKLVEALCAAGHRAELLRFPERSTEIGKLLSSYLQKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAARRGALIVLEGVDRAGKSTQSRKLVEALCAAGHRAELLRFPERSTEIGKLLSSYLQKK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 SDVEDHSVHLLFSANRWEQVPLIKEKLSQGVTLVVDRYAFSGVAFTGAKENFSLDWCKQP
::::::::::::::::::::
NP_001 SDVEDHSVHLLFSANRWEQVYSWRMLPSGERLAMSAMRTGLSRSGRSGVSTSS
70 80 90 100 110
212 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 06:05:25 2016 done: Sun Nov 6 06:05:26 2016
Total Scan time: 5.920 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]