Result of FASTA (omim) for
pFN21AE3049
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3049, 189 aa
1>>>pF1KE3049 189 - 189 aa - 189 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1839+/-0.000377; mu= 13.9375+/- 0.023
mean_var=60.8484+/-12.450, 0's: 0 Z-trim(112.0): 17 B-trim: 550 in 1/51
Lambda= 0.164418
statistics sampled from 20704 (20721) to 20704 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.619), E-opt: 0.2 (0.243), width: 16
Scan time: 5.610
The best scores are: opt bits E(85289)
NP_002163 (OMIM: 147579) interferon alpha-14 precu ( 189) 1247 304.0 9.1e-83
NP_002160 (OMIM: 147565) interferon alpha-5 precur ( 189) 1091 267.0 1.3e-71
NP_002162 (OMIM: 147577) interferon alpha-10 precu ( 189) 1072 262.5 2.8e-70
NP_066546 (OMIM: 147564) interferon alpha-4 precur ( 189) 1059 259.4 2.4e-69
NP_066282 (OMIM: 147566) interferon alpha-6 precur ( 189) 1052 257.8 7.6e-69
NP_067091 (OMIM: 147583) interferon alpha-17 precu ( 189) 1049 257.1 1.2e-68
NP_002164 (OMIM: 147580) interferon alpha-16 precu ( 189) 1040 254.9 5.5e-68
NP_008831 (OMIM: 147578) interferon alpha-1/13 pre ( 190) 1038 254.5 7.7e-68
NP_076918 (OMIM: 147660) interferon alpha-1/13 pre ( 189) 1033 253.3 1.7e-67
NP_066401 (OMIM: 147567) interferon alpha-7 precur ( 189) 1030 252.6 2.8e-67
NP_002166 (OMIM: 147584) interferon alpha-21 precu ( 189) 1026 251.6 5.5e-67
NP_000596 (OMIM: 147562) interferon alpha-2 precur ( 188) 1024 251.1 7.6e-67
NP_002161 (OMIM: 147568) interferon alpha-8 precur ( 189) 994 244.0 1.1e-64
NP_002168 (OMIM: 147553) interferon omega-1 precur ( 195) 699 174.1 1.3e-43
NP_795372 (OMIM: 615223) interferon epsilon precur ( 208) 376 97.5 1.5e-20
NP_002167 (OMIM: 147640) interferon beta precursor ( 187) 338 88.4 7.3e-18
NP_064509 (OMIM: 615326) interferon kappa precurso ( 207) 163 46.9 2.5e-05
>>NP_002163 (OMIM: 147579) interferon alpha-14 precursor (189 aa)
initn: 1247 init1: 1247 opt: 1247 Z-score: 1606.9 bits: 304.0 E(85289): 9.1e-83
Smith-Waterman score: 1247; 100.0% identity (100.0% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE3 MALPFALMMALVVLSCKSSCSLGCNLSQTHSLNNRRTLMLMAQMRRISPFSCLKDRHDFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MALPFALMMALVVLSCKSSCSLGCNLSQTHSLNNRRTLMLMAQMRRISPFSCLKDRHDFE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FPQEEFDGNQFQKAQAISVLHEMMQQTFNLFSTKNSSAAWDETLLEKFYIELFQQMNDLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 FPQEEFDGNQFQKAQAISVLHEMMQQTFNLFSTKNSSAAWDETLLEKFYIELFQQMNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 ACVIQEVGVEETPLMNEDSILAVKKYFQRITLYLMEKKYSPCAWEVVRAEIMRSLSFSTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ACVIQEVGVEETPLMNEDSILAVKKYFQRITLYLMEKKYSPCAWEVVRAEIMRSLSFSTN
130 140 150 160 170 180
pF1KE3 LQKRLRRKD
:::::::::
NP_002 LQKRLRRKD
>>NP_002160 (OMIM: 147565) interferon alpha-5 precursor (189 aa)
initn: 1091 init1: 1091 opt: 1091 Z-score: 1407.0 bits: 267.0 E(85289): 1.3e-71
Smith-Waterman score: 1091; 84.7% identity (96.3% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE3 MALPFALMMALVVLSCKSSCSLGCNLSQTHSLNNRRTLMLMAQMRRISPFSCLKDRHDFE
:::::.:.::::::.::: :::::.: :::::.::::::.:::: ::::::::::::::
NP_002 MALPFVLLMALVVLNCKSICSLGCDLPQTHSLSNRRTLMIMAQMGRISPFSCLKDRHDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FPQEEFDGNQFQKAQAISVLHEMMQQTFNLFSTKNSSAAWDETLLEKFYIELFQQMNDLE
:::::::::::::::::::::::.::::::::::.:::.::::::.::: ::.::.::::
NP_002 FPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWDETLLDKFYTELYQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 ACVIQEVGVEETPLMNEDSILAVKKYFQRITLYLMEKKYSPCAWEVVRAEIMRSLSFSTN
::..::::::.::::: ::::.:.:::::::::: :::::::::::::::::::.:.:.:
NP_002 ACMMQEVGVEDTPLMNVDSILTVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSLSAN
130 140 150 160 170 180
pF1KE3 LQKRLRRKD
::.:::::.
NP_002 LQERLRRKE
>>NP_002162 (OMIM: 147577) interferon alpha-10 precursor (189 aa)
initn: 1072 init1: 1072 opt: 1072 Z-score: 1382.6 bits: 262.5 E(85289): 2.8e-70
Smith-Waterman score: 1072; 84.1% identity (96.3% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE3 MALPFALMMALVVLSCKSSCSLGCNLSQTHSLNNRRTLMLMAQMRRISPFSCLKDRHDFE
::: :.:.::..::: :: :::::.: :::::.:::.:.:..:: ::::::::::::::.
NP_002 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLGQMGRISPFSCLKDRHDFR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FPQEEFDGNQFQKAQAISVLHEMMQQTFNLFSTKNSSAAWDETLLEKFYIELFQQMNDLE
.::::::::::::::::::::::.:::::::::..:::::...::::: ::.::.::::
NP_002 IPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 ACVIQEVGVEETPLMNEDSILAVKKYFQRITLYLMEKKYSPCAWEVVRAEIMRSLSFSTN
:::::::::::::::::::::::.::::::::::.:.:::::::::::::::::::::::
NP_002 ACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLIERKYSPCAWEVVRAEIMRSLSFSTN
130 140 150 160 170 180
pF1KE3 LQKRLRRKD
:::::::::
NP_002 LQKRLRRKD
>>NP_066546 (OMIM: 147564) interferon alpha-4 precursor (189 aa)
initn: 1059 init1: 1059 opt: 1059 Z-score: 1365.9 bits: 259.4 E(85289): 2.4e-69
Smith-Waterman score: 1059; 84.1% identity (94.7% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE3 MALPFALMMALVVLSCKSSCSLGCNLSQTHSLNNRRTLMLMAQMRRISPFSCLKDRHDFE
::: :.:.::..::: :: :::::.: :::::.:::.:.:.::: ::: ::::::::::
NP_066 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRHDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FPQEEFDGNQFQKAQAISVLHEMMQQTFNLFSTKNSSAAWDETLLEKFYIELFQQMNDLE
::.:::::.::::::::::::::.:::::::::..:::::...::::: ::.::.::::
NP_066 FPEEEFDGHQFQKAQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 ACVIQEVGVEETPLMNEDSILAVKKYFQRITLYLMEKKYSPCAWEVVRAEIMRSLSFSTN
:::::::::::::::::::::::.:::::::::: :::::::::::::::::::::::::
NP_066 ACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTN
130 140 150 160 170 180
pF1KE3 LQKRLRRKD
:::::::::
NP_066 LQKRLRRKD
>>NP_066282 (OMIM: 147566) interferon alpha-6 precursor (189 aa)
initn: 1104 init1: 1052 opt: 1052 Z-score: 1357.0 bits: 257.8 E(85289): 7.6e-69
Smith-Waterman score: 1052; 83.1% identity (94.2% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE3 MALPFALMMALVVLSCKSSCSLGCNLSQTHSLNNRRTLMLMAQMRRISPFSCLKDRHDFE
:::::::.:::::::::::::: :.: :::::..:::.::.::::::: ::::::::::.
NP_066 MALPFALLMALVVLSCKSSCSLDCDLPQTHSLGHRRTMMLLAQMRRISLFSCLKDRHDFR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FPQEEFDGNQFQKAQAISVLHEMMQQTFNLFSTKNSSAAWDETLLEKFYIELFQQMNDLE
::::::::::::::.:::::::..::::::::::.::.:::: ::.:.: ::.::.::::
NP_066 FPQEEFDGNQFQKAEAISVLHEVIQQTFNLFSTKDSSVAWDERLLDKLYTELYQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 ACVIQEVGVEETPLMNEDSILAVKKYFQRITLYLMEKKYSPCAWEVVRAEIMRSLSFSTN
:::.::: : ::::::::::::.:::::::::: :::::::::::::::::::.: : :
NP_066 ACVMQEVWVGGTPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSSSRN
130 140 150 160 170 180
pF1KE3 LQKRLRRKD
::.:::::.
NP_066 LQERLRRKE
>>NP_067091 (OMIM: 147583) interferon alpha-17 precursor (189 aa)
initn: 1049 init1: 1049 opt: 1049 Z-score: 1353.1 bits: 257.1 E(85289): 1.2e-68
Smith-Waterman score: 1049; 83.1% identity (94.7% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE3 MALPFALMMALVVLSCKSSCSLGCNLSQTHSLNNRRTLMLMAQMRRISPFSCLKDRHDFE
::: :.:.::..::: :: :::::.: :::::.:::.:.:.::: ::::::::::::::
NP_067 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FPQEEFDGNQFQKAQAISVLHEMMQQTFNLFSTKNSSAAWDETLLEKFYIELFQQMNDLE
.::::::::::::.:::::::::.:::::::::..:::::...::::: ::.::.:.::
NP_067 LPQEEFDGNQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNNLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 ACVIQEVGVEETPLMNEDSILAVKKYFQRITLYLMEKKYSPCAWEVVRAEIMRSLSFSTN
::::::::.::::::::::::::.:::::::::: :::::::::::::::::::::::::
NP_067 ACVIQEVGMEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTN
130 140 150 160 170 180
pF1KE3 LQKRLRRKD
::: :::::
NP_067 LQKILRRKD
>>NP_002164 (OMIM: 147580) interferon alpha-16 precursor (189 aa)
initn: 1040 init1: 1040 opt: 1040 Z-score: 1341.6 bits: 254.9 E(85289): 5.5e-68
Smith-Waterman score: 1040; 83.6% identity (93.1% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE3 MALPFALMMALVVLSCKSSCSLGCNLSQTHSLNNRRTLMLMAQMRRISPFSCLKDRHDFE
::: :.:.::..::: :: :::::.: :::::.:::.:.:.::: ::: :::::::.::
NP_002 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRYDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FPQEEFDGNQFQKAQAISVLHEMMQQTFNLFSTKNSSAAWDETLLEKFYIELFQQMNDLE
:::: :::::::::::::..:::.::::::::::.::::::::::.:::::::::.::::
NP_002 FPQEVFDGNQFQKAQAISAFHEMIQQTFNLFSTKDSSAAWDETLLDKFYIELFQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 ACVIQEVGVEETPLMNEDSILAVKKYFQRITLYLMEKKYSPCAWEVVRAEIMRSLSFSTN
::: ::::::: ::::::::::.::::::::::: ::::::::::::::::::.:::::
NP_002 ACVTQEVGVEEIALMNEDSILAVRKYFQRITLYLMGKKYSPCAWEVVRAEIMRSFSFSTN
130 140 150 160 170 180
pF1KE3 LQKRLRRKD
::: :::::
NP_002 LQKGLRRKD
>>NP_008831 (OMIM: 147578) interferon alpha-1/13 precurs (190 aa)
initn: 1099 init1: 1038 opt: 1038 Z-score: 1339.0 bits: 254.5 E(85289): 7.7e-68
Smith-Waterman score: 1038; 82.5% identity (91.5% similar) in 189 aa overlap (1-189:2-190)
10 20 30 40 50
pF1KE3 MALPFALMMALVVLSCKSSCSLGCNLSQTHSLNNRRTLMLMAQMRRISPFSCLKDRHDF
:: ::::.::::::::::::::::.: .::::.:::::::.::: :::: ::: :::::
NP_008 MMASPFALLMALVVLSCKSSCSLGCDLPETHSLDNRRTLMLLAQMSRISPSSCLMDRHDF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 EFPQEEFDGNQFQKAQAISVLHEMMQQTFNLFSTKNSSAAWDETLLEKFYIELFQQMNDL
:::::::::::::: :::::::..:: ::::.::.::::::: ::.:: ::.::.:::
NP_008 GFPQEEFDGNQFQKAPAISVLHELIQQIFNLFTTKDSSAAWDEDLLDKFCTELYQQLNDL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE3 EACVIQEVGVEETPLMNEDSILAVKKYFQRITLYLMEKKYSPCAWEVVRAEIMRSLSFST
::::.:: : :::::: ::::::::::.:::::: :::::::::::::::::::::.::
NP_008 EACVMQEERVGETPLMNADSILAVKKYFRRITLYLTEKKYSPCAWEVVRAEIMRSLSLST
130 140 150 160 170 180
180
pF1KE3 NLQKRLRRKD
:::.:::::.
NP_008 NLQERLRRKE
190
>>NP_076918 (OMIM: 147660) interferon alpha-1/13 precurs (189 aa)
initn: 1092 init1: 1033 opt: 1033 Z-score: 1332.6 bits: 253.3 E(85289): 1.7e-67
Smith-Waterman score: 1033; 82.0% identity (91.5% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE3 MALPFALMMALVVLSCKSSCSLGCNLSQTHSLNNRRTLMLMAQMRRISPFSCLKDRHDFE
:: ::::.:.::::::::::::::.: .::::.:::::::.::: :::: ::: :::::
NP_076 MASPFALLMVLVVLSCKSSCSLGCDLPETHSLDNRRTLMLLAQMSRISPSSCLMDRHDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FPQEEFDGNQFQKAQAISVLHEMMQQTFNLFSTKNSSAAWDETLLEKFYIELFQQMNDLE
:::::::::::::: :::::::..:: ::::.::.::::::: ::.:: ::.::.::::
NP_076 FPQEEFDGNQFQKAPAISVLHELIQQIFNLFTTKDSSAAWDEDLLDKFCTELYQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 ACVIQEVGVEETPLMNEDSILAVKKYFQRITLYLMEKKYSPCAWEVVRAEIMRSLSFSTN
:::.:: : :::::: ::::::::::.:::::: :::::::::::::::::::::.:::
NP_076 ACVMQEERVGETPLMNADSILAVKKYFRRITLYLTEKKYSPCAWEVVRAEIMRSLSLSTN
130 140 150 160 170 180
pF1KE3 LQKRLRRKD
::.:::::.
NP_076 LQERLRRKE
>>NP_066401 (OMIM: 147567) interferon alpha-7 precursor (189 aa)
initn: 1030 init1: 1030 opt: 1030 Z-score: 1328.8 bits: 252.6 E(85289): 2.8e-67
Smith-Waterman score: 1030; 81.0% identity (94.2% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE3 MALPFALMMALVVLSCKSSCSLGCNLSQTHSLNNRRTLMLMAQMRRISPFSCLKDRHDFE
:: :.:.:...::: :: :::::.: ::::: :::.:.:.::: ::::::::::::.:.
NP_066 MARSFSLLMVVLVLSYKSICSLGCDLPQTHSLRNRRALILLAQMGRISPFSCLKDRHEFR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FPQEEFDGNQFQKAQAISVLHEMMQQTFNLFSTKNSSAAWDETLLEKFYIELFQQMNDLE
::.:::::.::::.:::::::::.:::::::::..:::::...::::: ::.::.::::
NP_066 FPEEEFDGHQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 ACVIQEVGVEETPLMNEDSILAVKKYFQRITLYLMEKKYSPCAWEVVRAEIMRSLSFSTN
:::::::::::::::::: ::::.::::::::::::::::::::::::::::::.:::::
NP_066 ACVIQEVGVEETPLMNEDFILAVRKYFQRITLYLMEKKYSPCAWEVVRAEIMRSFSFSTN
130 140 150 160 170 180
pF1KE3 LQKRLRRKD
:.: :::::
NP_066 LKKGLRRKD
189 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 04:54:37 2016 done: Sun Nov 6 04:54:38 2016
Total Scan time: 5.610 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]