Result of FASTA (omim) for
pFN21AE3048
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3048, 189 aa
1>>>pF1KE3048 189 - 189 aa - 189 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1439+/-0.000366; mu= 13.8030+/- 0.023
mean_var=63.4926+/-12.863, 0's: 0 Z-trim(112.6): 21 B-trim: 1291 in 1/51
Lambda= 0.160958
statistics sampled from 21595 (21612) to 21595 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.649), E-opt: 0.2 (0.253), width: 16
Scan time: 5.720
The best scores are: opt bits E(85289)
NP_066401 (OMIM: 147567) interferon alpha-7 precur ( 189) 1241 296.6 1.5e-80
NP_066546 (OMIM: 147564) interferon alpha-4 precur ( 189) 1144 274.1 9.2e-74
NP_002162 (OMIM: 147577) interferon alpha-10 precu ( 189) 1140 273.2 1.8e-73
NP_067091 (OMIM: 147583) interferon alpha-17 precu ( 189) 1130 270.9 8.8e-73
NP_002166 (OMIM: 147584) interferon alpha-21 precu ( 189) 1079 259.0 3.2e-69
NP_002164 (OMIM: 147580) interferon alpha-16 precu ( 189) 1061 254.8 5.8e-68
NP_002163 (OMIM: 147579) interferon alpha-14 precu ( 189) 1030 247.7 8.6e-66
NP_002160 (OMIM: 147565) interferon alpha-5 precur ( 189) 1022 245.8 3.1e-65
NP_066282 (OMIM: 147566) interferon alpha-6 precur ( 189) 959 231.2 7.9e-61
NP_076918 (OMIM: 147660) interferon alpha-1/13 pre ( 189) 958 230.9 9.3e-61
NP_000596 (OMIM: 147562) interferon alpha-2 precur ( 188) 954 230.0 1.8e-60
NP_008831 (OMIM: 147578) interferon alpha-1/13 pre ( 190) 953 229.8 2.1e-60
NP_002161 (OMIM: 147568) interferon alpha-8 precur ( 189) 951 229.3 2.9e-60
NP_002168 (OMIM: 147553) interferon omega-1 precur ( 195) 685 167.5 1.2e-41
NP_795372 (OMIM: 615223) interferon epsilon precur ( 208) 355 90.9 1.4e-18
NP_002167 (OMIM: 147640) interferon beta precursor ( 187) 330 85.1 7.3e-17
NP_064509 (OMIM: 615326) interferon kappa precurso ( 207) 160 45.6 6.1e-05
>>NP_066401 (OMIM: 147567) interferon alpha-7 precursor (189 aa)
initn: 1241 init1: 1241 opt: 1241 Z-score: 1567.0 bits: 296.6 E(85289): 1.5e-80
Smith-Waterman score: 1241; 100.0% identity (100.0% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE3 MARSFSLLMVVLVLSYKSICSLGCDLPQTHSLRNRRALILLAQMGRISPFSCLKDRHEFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 MARSFSLLMVVLVLSYKSICSLGCDLPQTHSLRNRRALILLAQMGRISPFSCLKDRHEFR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FPEEEFDGHQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 FPEEEFDGHQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 ACVIQEVGVEETPLMNEDFILAVRKYFQRITLYLMEKKYSPCAWEVVRAEIMRSFSFSTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 ACVIQEVGVEETPLMNEDFILAVRKYFQRITLYLMEKKYSPCAWEVVRAEIMRSFSFSTN
130 140 150 160 170 180
pF1KE3 LKKGLRRKD
:::::::::
NP_066 LKKGLRRKD
>>NP_066546 (OMIM: 147564) interferon alpha-4 precursor (189 aa)
initn: 1144 init1: 1144 opt: 1144 Z-score: 1445.2 bits: 274.1 E(85289): 9.2e-74
Smith-Waterman score: 1144; 93.7% identity (96.3% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE3 MARSFSLLMVVLVLSYKSICSLGCDLPQTHSLRNRRALILLAQMGRISPFSCLKDRHEFR
:: ::::::.:::::::::::::::::::::: ::::::::::::::: ::::::::.:
NP_066 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRHDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FPEEEFDGHQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
:::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::
NP_066 FPEEEFDGHQFQKAQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 ACVIQEVGVEETPLMNEDFILAVRKYFQRITLYLMEKKYSPCAWEVVRAEIMRSFSFSTN
:::::::::::::::::: ::::::::::::::: :::::::::::::::::::.:::::
NP_066 ACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTN
130 140 150 160 170 180
pF1KE3 LKKGLRRKD
:.: :::::
NP_066 LQKRLRRKD
>>NP_002162 (OMIM: 147577) interferon alpha-10 precursor (189 aa)
initn: 1140 init1: 1140 opt: 1140 Z-score: 1440.2 bits: 273.2 E(85289): 1.8e-73
Smith-Waterman score: 1140; 92.1% identity (97.9% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE3 MARSFSLLMVVLVLSYKSICSLGCDLPQTHSLRNRRALILLAQMGRISPFSCLKDRHEFR
:: ::::::.:::::::::::::::::::::: ::::::::.:::::::::::::::.::
NP_002 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLGQMGRISPFSCLKDRHDFR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FPEEEFDGHQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
.:.:::::.::::.::::::::::::::::::::::::::::::::::::::::::::::
NP_002 IPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 ACVIQEVGVEETPLMNEDFILAVRKYFQRITLYLMEKKYSPCAWEVVRAEIMRSFSFSTN
:::::::::::::::::: :::::::::::::::.:.:::::::::::::::::.:::::
NP_002 ACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLIERKYSPCAWEVVRAEIMRSLSFSTN
130 140 150 160 170 180
pF1KE3 LKKGLRRKD
:.: :::::
NP_002 LQKRLRRKD
>>NP_067091 (OMIM: 147583) interferon alpha-17 precursor (189 aa)
initn: 1130 init1: 1130 opt: 1130 Z-score: 1427.7 bits: 270.9 E(85289): 8.8e-73
Smith-Waterman score: 1130; 92.1% identity (96.8% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE3 MARSFSLLMVVLVLSYKSICSLGCDLPQTHSLRNRRALILLAQMGRISPFSCLKDRHEFR
:: ::::::.:::::::::::::::::::::: ::::::::::::::::::::::::.:
NP_067 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FPEEEFDGHQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
.:.:::::.::::::::::::::::::::::::::::::::::::::::::::::::.::
NP_067 LPQEEFDGNQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNNLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 ACVIQEVGVEETPLMNEDFILAVRKYFQRITLYLMEKKYSPCAWEVVRAEIMRSFSFSTN
::::::::.::::::::: ::::::::::::::: :::::::::::::::::::.:::::
NP_067 ACVIQEVGMEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTN
130 140 150 160 170 180
pF1KE3 LKKGLRRKD
:.: :::::
NP_067 LQKILRRKD
>>NP_002166 (OMIM: 147584) interferon alpha-21 precursor (189 aa)
initn: 1113 init1: 1079 opt: 1079 Z-score: 1363.7 bits: 259.0 E(85289): 3.2e-69
Smith-Waterman score: 1079; 87.8% identity (94.7% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE3 MARSFSLLMVVLVLSYKSICSLGCDLPQTHSLRNRRALILLAQMGRISPFSCLKDRHEFR
:: ::::::.:::::::::::::::::::::: ::::::::::::::::::::::::.:
NP_002 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FPEEEFDGHQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
::.:::::.::::.:::::::::::::::::::.::::.::::::::::::: :::::::
NP_002 FPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWEQSLLEKFSTELNQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 ACVIQEVGVEETPLMNEDFILAVRKYFQRITLYLMEKKYSPCAWEVVRAEIMRSFSFSTN
:::::::::::::::: : ::::.:::::::::: :::::::::::::::::::::.:
NP_002 ACVIQEVGVEETPLMNVDSILAVKKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSLSKI
130 140 150 160 170 180
pF1KE3 LKKGLRRKD
... ::::.
NP_002 FQERLRRKE
>>NP_002164 (OMIM: 147580) interferon alpha-16 precursor (189 aa)
initn: 1061 init1: 1061 opt: 1061 Z-score: 1341.1 bits: 254.8 E(85289): 5.8e-68
Smith-Waterman score: 1061; 85.7% identity (93.7% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE3 MARSFSLLMVVLVLSYKSICSLGCDLPQTHSLRNRRALILLAQMGRISPFSCLKDRHEFR
:: ::::::.:::::::::::::::::::::: ::::::::::::::: :::::::..:
NP_002 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRYDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FPEEEFDGHQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
::.: :::.::::.::::..:::::::::::::.::::::...::.:: ::.:::::::
NP_002 FPQEVFDGNQFQKAQAISAFHEMIQQTFNLFSTKDSSAAWDETLLDKFYIELFQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 ACVIQEVGVEETPLMNEDFILAVRKYFQRITLYLMEKKYSPCAWEVVRAEIMRSFSFSTN
::: ::::::: ::::: :::::::::::::::: ::::::::::::::::::::::::
NP_002 ACVTQEVGVEEIALMNEDSILAVRKYFQRITLYLMGKKYSPCAWEVVRAEIMRSFSFSTN
130 140 150 160 170 180
pF1KE3 LKKGLRRKD
:.:::::::
NP_002 LQKGLRRKD
>>NP_002163 (OMIM: 147579) interferon alpha-14 precursor (189 aa)
initn: 1030 init1: 1030 opt: 1030 Z-score: 1302.2 bits: 247.7 E(85289): 8.6e-66
Smith-Waterman score: 1030; 81.0% identity (94.2% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE3 MARSFSLLMVVLVLSYKSICSLGCDLPQTHSLRNRRALILLAQMGRISPFSCLKDRHEFR
:: :.:.:...::: :: :::::.: ::::: :::.:.:.::: ::::::::::::.:.
NP_002 MALPFALMMALVVLSCKSSCSLGCNLSQTHSLNNRRTLMLMAQMRRISPFSCLKDRHDFE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FPEEEFDGHQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
::.:::::.::::.:::::::::.:::::::::..:::::...::::: ::.::.::::
NP_002 FPQEEFDGNQFQKAQAISVLHEMMQQTFNLFSTKNSSAAWDETLLEKFYIELFQQMNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 ACVIQEVGVEETPLMNEDFILAVRKYFQRITLYLMEKKYSPCAWEVVRAEIMRSFSFSTN
:::::::::::::::::: ::::.::::::::::::::::::::::::::::::.:::::
NP_002 ACVIQEVGVEETPLMNEDSILAVKKYFQRITLYLMEKKYSPCAWEVVRAEIMRSLSFSTN
130 140 150 160 170 180
pF1KE3 LKKGLRRKD
:.: :::::
NP_002 LQKRLRRKD
>>NP_002160 (OMIM: 147565) interferon alpha-5 precursor (189 aa)
initn: 1039 init1: 1022 opt: 1022 Z-score: 1292.1 bits: 245.8 E(85289): 3.1e-65
Smith-Waterman score: 1022; 79.9% identity (94.2% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE3 MARSFSLLMVVLVLSYKSICSLGCDLPQTHSLRNRRALILLAQMGRISPFSCLKDRHEFR
:: : :::...::. :::::::::::::::: :::.:...::::::::::::::::.:
NP_002 MALPFVLLMALVVLNCKSICSLGCDLPQTHSLSNRRTLMIMAQMGRISPFSCLKDRHDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FPEEEFDGHQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
::.:::::.::::.:::::::::::::::::::.::::.:...::.:: :::::::::::
NP_002 FPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWDETLLDKFYTELYQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 ACVIQEVGVEETPLMNEDFILAVRKYFQRITLYLMEKKYSPCAWEVVRAEIMRSFSFSTN
::..::::::.::::: : ::.:::::::::::: :::::::::::::::::::::.:.:
NP_002 ACMMQEVGVEDTPLMNVDSILTVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSLSAN
130 140 150 160 170 180
pF1KE3 LKKGLRRKD
:.. ::::.
NP_002 LQERLRRKE
>>NP_066282 (OMIM: 147566) interferon alpha-6 precursor (189 aa)
initn: 974 init1: 959 opt: 959 Z-score: 1213.1 bits: 231.2 E(85289): 7.9e-61
Smith-Waterman score: 959; 77.8% identity (90.5% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE3 MARSFSLLMVVLVLSYKSICSLGCDLPQTHSLRNRRALILLAQMGRISPFSCLKDRHEFR
:: :.:::...::: :: ::: ::::::::: .::...::::: ::: ::::::::.::
NP_066 MALPFALLMALVVLSCKSSCSLDCDLPQTHSLGHRRTMMLLAQMRRISLFSCLKDRHDFR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FPEEEFDGHQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
::.:::::.::::..:::::::.::::::::::.:::.::.. ::.:. :::::::::::
NP_066 FPQEEFDGNQFQKAEAISVLHEVIQQTFNLFSTKDSSVAWDERLLDKLYTELYQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 ACVIQEVGVEETPLMNEDFILAVRKYFQRITLYLMEKKYSPCAWEVVRAEIMRSFSFSTN
:::.::: : ::::::: ::::::::::::::: ::::::::::::::::::::: : :
NP_066 ACVMQEVWVGGTPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSSSRN
130 140 150 160 170 180
pF1KE3 LKKGLRRKD
:.. ::::.
NP_066 LQERLRRKE
>>NP_076918 (OMIM: 147660) interferon alpha-1/13 precurs (189 aa)
initn: 973 init1: 958 opt: 958 Z-score: 1211.8 bits: 230.9 E(85289): 9.3e-61
Smith-Waterman score: 958; 76.7% identity (90.5% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE3 MARSFSLLMVVLVLSYKSICSLGCDLPQTHSLRNRRALILLAQMGRISPFSCLKDRHEFR
:: :.::::..::: :: ::::::::.:::: :::.:.:::::.:::: ::: :::.:
NP_076 MASPFALLMVLVVLSCKSSCSLGCDLPETHSLDNRRTLMLLAQMSRISPSSCLMDRHDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FPEEEFDGHQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
::.:::::.::::. :::::::.::: ::::.:.::::::...::.:: :::::::::::
NP_076 FPQEEFDGNQFQKAPAISVLHELIQQIFNLFTTKDSSAAWDEDLLDKFCTELYQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 ACVIQEVGVEETPLMNEDFILAVRKYFQRITLYLMEKKYSPCAWEVVRAEIMRSFSFSTN
:::.:: : :::::: : ::::.:::.:::::: :::::::::::::::::::.:.:::
NP_076 ACVMQEERVGETPLMNADSILAVKKYFRRITLYLTEKKYSPCAWEVVRAEIMRSLSLSTN
130 140 150 160 170 180
pF1KE3 LKKGLRRKD
:.. ::::.
NP_076 LQERLRRKE
189 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 04:54:05 2016 done: Sun Nov 6 04:54:05 2016
Total Scan time: 5.720 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]