Result of FASTA (ccds) for
pFN21AE3044
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3044, 183 aa
1>>>pF1KE3044 183 - 183 aa - 183 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1826+/-0.000944; mu= 13.7218+/- 0.057
mean_var=83.8883+/-17.446, 0's: 0 Z-trim(107.0): 195 B-trim: 271 in 1/50
Lambda= 0.140031
statistics sampled from 9094 (9317) to 9094 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.679), E-opt: 0.2 (0.286), width: 16
Scan time: 1.730
The best scores are: opt bits E(32554)
CCDS14632.1 RAP2C gene_id:57826|Hs108|chrX ( 183) 1193 250.5 4.4e-67
CCDS9485.1 RAP2A gene_id:5911|Hs108|chr13 ( 183) 1109 233.5 5.6e-62
CCDS3170.1 RAP2B gene_id:5912|Hs108|chr3 ( 183) 1050 221.6 2.2e-58
CCDS76024.1 RAP2C gene_id:57826|Hs108|chrX ( 117) 781 167.0 3.6e-42
CCDS840.1 RAP1A gene_id:5906|Hs108|chr1 ( 184) 744 159.7 8.9e-40
CCDS8984.1 RAP1B gene_id:5908|Hs108|chr12 ( 184) 731 157.1 5.5e-39
CCDS8702.1 KRAS gene_id:3845|Hs108|chr12 ( 188) 583 127.2 5.6e-30
CCDS8703.1 KRAS gene_id:3845|Hs108|chr12 ( 189) 581 126.8 7.4e-30
CCDS7698.1 HRAS gene_id:3265|Hs108|chr11 ( 189) 578 126.2 1.1e-29
CCDS877.1 NRAS gene_id:4893|Hs108|chr1 ( 189) 574 125.4 2e-29
CCDS1123.1 RIT1 gene_id:6016|Hs108|chr1 ( 219) 574 125.5 2.2e-29
CCDS58037.1 RIT1 gene_id:6016|Hs108|chr1 ( 236) 574 125.5 2.3e-29
CCDS11921.1 RIT2 gene_id:6014|Hs108|chr18 ( 217) 568 124.3 5.1e-29
CCDS2131.1 RALB gene_id:5899|Hs108|chr2 ( 206) 549 120.4 7e-28
CCDS6687.1 DIRAS2 gene_id:54769|Hs108|chr9 ( 199) 541 118.8 2.1e-27
CCDS7699.1 HRAS gene_id:3265|Hs108|chr11 ( 170) 534 117.3 5e-27
CCDS7814.1 RRAS2 gene_id:22800|Hs108|chr11 ( 204) 530 116.6 9.9e-27
CCDS5460.1 RALA gene_id:5898|Hs108|chr7 ( 206) 521 114.7 3.5e-26
CCDS3100.1 MRAS gene_id:22808|Hs108|chr3 ( 208) 518 114.1 5.4e-26
CCDS12092.1 DIRAS1 gene_id:148252|Hs108|chr19 ( 198) 511 112.7 1.4e-25
CCDS12774.1 RRAS gene_id:6237|Hs108|chr19 ( 218) 507 111.9 2.6e-25
CCDS58036.1 RIT1 gene_id:6016|Hs108|chr1 ( 183) 481 106.6 8.8e-24
CCDS62431.1 RIT2 gene_id:6014|Hs108|chr18 ( 153) 459 102.1 1.7e-22
CCDS8673.1 RERG gene_id:85004|Hs108|chr12 ( 199) 437 97.8 4.4e-21
CCDS8778.1 RHEBL1 gene_id:121268|Hs108|chr12 ( 183) 433 96.9 7.3e-21
CCDS53603.1 RRAS2 gene_id:22800|Hs108|chr11 ( 169) 423 94.9 2.8e-20
CCDS58253.1 RAP1B gene_id:5908|Hs108|chr12 ( 165) 419 94.0 4.8e-20
CCDS58254.1 RAP1B gene_id:5908|Hs108|chr12 ( 142) 413 92.8 1e-19
CCDS5927.1 RHEB gene_id:6009|Hs108|chr7 ( 184) 409 92.1 2.1e-19
CCDS641.1 DIRAS3 gene_id:9077|Hs108|chr1 ( 229) 366 83.5 1e-16
CCDS35246.1 ERAS gene_id:3266|Hs108|chrX ( 233) 363 82.9 1.6e-16
CCDS11703.1 RAB37 gene_id:326624|Hs108|chr17 ( 216) 360 82.2 2.3e-16
CCDS82198.1 RAB37 gene_id:326624|Hs108|chr17 ( 196) 359 82.0 2.4e-16
CCDS32722.1 RAB37 gene_id:326624|Hs108|chr17 ( 223) 359 82.0 2.7e-16
CCDS54161.1 RAB37 gene_id:326624|Hs108|chr17 ( 228) 359 82.1 2.7e-16
CCDS10460.1 RAB26 gene_id:25837|Hs108|chr16 ( 256) 359 82.1 2.9e-16
CCDS14766.1 RAB39B gene_id:116442|Hs108|chrX ( 213) 349 80.0 1e-15
CCDS13181.1 REM1 gene_id:28954|Hs108|chr20 ( 298) 349 80.1 1.3e-15
CCDS46306.1 RAB1A gene_id:5861|Hs108|chr2 ( 205) 345 79.2 1.8e-15
CCDS76806.1 RAB26 gene_id:25837|Hs108|chr16 ( 190) 344 79.0 1.9e-15
CCDS31613.1 RAB1B gene_id:81876|Hs108|chr11 ( 201) 343 78.8 2.3e-15
CCDS14156.1 RAB9A gene_id:9367|Hs108|chrX ( 201) 341 78.4 3.1e-15
CCDS10200.1 RASL12 gene_id:51285|Hs108|chr15 ( 266) 340 78.3 4.3e-15
CCDS14515.1 RAB9B gene_id:51209|Hs108|chrX ( 201) 337 77.6 5.4e-15
CCDS42410.1 RAB12 gene_id:201475|Hs108|chr18 ( 244) 337 77.6 6.2e-15
CCDS6175.1 RAB2A gene_id:5862|Hs108|chr8 ( 212) 335 77.2 7.4e-15
CCDS1058.1 RAB13 gene_id:5872|Hs108|chr1 ( 203) 332 76.6 1.1e-14
CCDS11185.1 RASD1 gene_id:51655|Hs108|chr17 ( 281) 332 76.7 1.4e-14
CCDS6261.1 GEM gene_id:2669|Hs108|chr8 ( 296) 330 76.3 1.9e-14
CCDS2520.1 RAB17 gene_id:64284|Hs108|chr2 ( 212) 328 75.8 2e-14
>>CCDS14632.1 RAP2C gene_id:57826|Hs108|chrX (183 aa)
initn: 1193 init1: 1193 opt: 1193 Z-score: 1317.8 bits: 250.5 E(32554): 4.4e-67
Smith-Waterman score: 1193; 100.0% identity (100.0% similar) in 183 aa overlap (1-183:1-183)
10 20 30 40 50 60
pF1KE3 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVKRYEKVPLILVGNKVDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVKRYEKVPLILVGNKVDL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 EPEREVMSSEGRALAQEWGCPFMETSAKSKSMVDELFAEIVRQMNYSSLPEKQDQCCTTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 EPEREVMSSEGRALAQEWGCPFMETSAKSKSMVDELFAEIVRQMNYSSLPEKQDQCCTTC
130 140 150 160 170 180
pF1KE3 VVQ
:::
CCDS14 VVQ
>>CCDS9485.1 RAP2A gene_id:5911|Hs108|chr13 (183 aa)
initn: 1126 init1: 1109 opt: 1109 Z-score: 1226.1 bits: 233.5 E(32554): 5.6e-62
Smith-Waterman score: 1109; 91.3% identity (97.3% similar) in 183 aa overlap (1-183:1-183)
10 20 30 40 50 60
pF1KE3 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS94 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVKRYEKVPLILVGNKVDL
::::::::::::::::::::::::::::::::::::::::.:::::::::.:::::::::
CCDS94 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 EPEREVMSSEGRALAQEWGCPFMETSAKSKSMVDELFAEIVRQMNYSSLPEKQDQCCTTC
: :::: ::::::::.::::::::::::::.:::::::::::::::.. :.:.: ::..:
CCDS94 ESEREVSSSEGRALAEEWGCPFMETSAKSKTMVDELFAEIVRQMNYAAQPDKDDPCCSAC
130 140 150 160 170 180
pF1KE3 VVQ
.:
CCDS94 NIQ
>>CCDS3170.1 RAP2B gene_id:5912|Hs108|chr3 (183 aa)
initn: 1067 init1: 1050 opt: 1050 Z-score: 1161.7 bits: 221.6 E(32554): 2.2e-58
Smith-Waterman score: 1050; 86.3% identity (96.2% similar) in 182 aa overlap (1-182:1-182)
10 20 30 40 50 60
pF1KE3 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG
::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::
CCDS31 MREYKVVVLGSGGVGKSALTVQFVTGSFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVKRYEKVPLILVGNKVDL
::::::::::::::::::::::::::::::::::::::::.::::::.::.:::::::::
CCDS31 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYERVPMILVGNKVDL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 EPEREVMSSEGRALAQEWGCPFMETSAKSKSMVDELFAEIVRQMNYSSLPEKQDQCCTTC
: :::: .::.:::.::.:::::::::.:. ::::::::::::::.. :. .. ::..:
CCDS31 EGEREVSYGEGKALAEEWSCPFMETSAKNKASVDELFAEIVRQMNYAAQPNGDEGCCSAC
130 140 150 160 170 180
pF1KE3 VVQ
:.
CCDS31 VIL
>>CCDS76024.1 RAP2C gene_id:57826|Hs108|chrX (117 aa)
initn: 781 init1: 781 opt: 781 Z-score: 870.5 bits: 167.0 E(32554): 3.6e-42
Smith-Waterman score: 781; 100.0% identity (100.0% similar) in 117 aa overlap (67-183:1-117)
40 50 60 70 80 90
pF1KE3 EDFYRKEIEVDSSPSVLEILDTAGTEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPM
::::::::::::::::::::::::::::::
CCDS76 MRDLYIKNGQGFILVYSLVNQQSFQDIKPM
10 20 30
100 110 120 130 140 150
pF1KE3 RDQIVRVKRYEKVPLILVGNKVDLEPEREVMSSEGRALAQEWGCPFMETSAKSKSMVDEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 RDQIVRVKRYEKVPLILVGNKVDLEPEREVMSSEGRALAQEWGCPFMETSAKSKSMVDEL
40 50 60 70 80 90
160 170 180
pF1KE3 FAEIVRQMNYSSLPEKQDQCCTTCVVQ
:::::::::::::::::::::::::::
CCDS76 FAEIVRQMNYSSLPEKQDQCCTTCVVQ
100 110
>>CCDS840.1 RAP1A gene_id:5906|Hs108|chr1 (184 aa)
initn: 703 init1: 634 opt: 744 Z-score: 827.6 bits: 159.7 E(32554): 8.9e-40
Smith-Waterman score: 744; 61.7% identity (83.1% similar) in 183 aa overlap (1-182:1-183)
10 20 30 40 50 60
pF1KE3 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG
:::::.:::::::::::::::::: : :.::::::::: :::..::: . .::::::::
CCDS84 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVKRYEKVPLILVGNKVDL
::::..:::::.:::::: ::::.. :..:.:.. .:.::.::: : ::.:::::: ::
CCDS84 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDL
70 80 90 100 110 120
130 140 150 160 170
pF1KE3 EPEREVMSSEGRALAQEW-GCPFMETSAKSKSMVDELFAEIVRQMNYSSLPEKQDQCCTT
: :: : . .:. ::..: .: :.:.::::: :.:.: ..:::.: .. ::. .
CCDS84 EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKS
130 140 150 160 170 180
180
pF1KE3 CVVQ
:..
CCDS84 CLLL
>>CCDS8984.1 RAP1B gene_id:5908|Hs108|chr12 (184 aa)
initn: 694 init1: 632 opt: 731 Z-score: 813.4 bits: 157.1 E(32554): 5.5e-39
Smith-Waterman score: 731; 61.9% identity (85.1% similar) in 181 aa overlap (1-176:1-181)
10 20 30 40 50 60
pF1KE3 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG
:::::.:::::::::::::::::: : :.::::::::: :::..:::.. .::::::::
CCDS89 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVKRYEKVPLILVGNKVDL
::::..:::::.:::::: ::::.. :..:.:.. .:.::.::: . ::.:::::: ::
CCDS89 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDL
70 80 90 100 110 120
130 140 150 160 170
pF1KE3 EPEREVMSSEGRALAQEWG-CPFMETSAKSKSMVDELFAEIVRQMNYSS-LP---EKQDQ
: :: : . .:. ::..:. : :.:.::::: :.:.: ..:::.: .. .: .:...
CCDS89 EDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARKKSS
130 140 150 160 170 180
180
pF1KE3 CCTTCVVQ
:
CCDS89 CQLL
>>CCDS8702.1 KRAS gene_id:3845|Hs108|chr12 (188 aa)
initn: 560 init1: 471 opt: 583 Z-score: 651.7 bits: 127.2 E(32554): 5.6e-30
Smith-Waterman score: 583; 46.8% identity (76.1% similar) in 188 aa overlap (1-182:1-187)
10 20 30 40 50 60
pF1KE3 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG
: :::.::.:.:::::::::.:.. . :...::::::: :::.. .:. .:.::::::
CCDS87 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVKRYEKVPLILVGNKVDL
:....::: :...:.::. :... : .::.::. .:.:: ::: : ::..::::: ::
CCDS87 QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDL
70 80 90 100 110 120
130 140 150 160 170
pF1KE3 EPEREVMSSEGRALAQEWGCPFMETSAKSKSMVDELFAEIVRQMNYSSLPEKQD------
: : : ..... ::. .: ::.:::::... ::. : .::.. . ..:
CCDS87 -PSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKEKMSKDGKKKKK
130 140 150 160 170
180
pF1KE3 QCCTTCVVQ
. : ::.
CCDS87 KSKTKCVIM
180
>>CCDS8703.1 KRAS gene_id:3845|Hs108|chr12 (189 aa)
initn: 555 init1: 471 opt: 581 Z-score: 649.5 bits: 126.8 E(32554): 7.4e-30
Smith-Waterman score: 581; 47.3% identity (78.0% similar) in 182 aa overlap (1-181:1-181)
10 20 30 40 50 60
pF1KE3 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG
: :::.::.:.:::::::::.:.. . :...::::::: :::.. .:. .:.::::::
CCDS87 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVKRYEKVPLILVGNKVDL
:....::: :...:.::. :... : .::.::. .:.:: ::: : ::..::::: ::
CCDS87 QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDL
70 80 90 100 110 120
130 140 150 160 170
pF1KE3 EPEREVMSSEGRALAQEWGCPFMETSAKSKSMVDELFAEIVRQMNYSSLPE-KQDQCCTT
: : : ..... ::. .: ::.:::::... :.. : .::.. : . ....
CCDS87 -PSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPG
130 140 150 160 170
180
pF1KE3 CVVQ
::
CCDS87 CVKIKKCIIM
180
>>CCDS7698.1 HRAS gene_id:3265|Hs108|chr11 (189 aa)
initn: 549 init1: 468 opt: 578 Z-score: 646.2 bits: 126.2 E(32554): 1.1e-29
Smith-Waterman score: 578; 45.9% identity (76.2% similar) in 185 aa overlap (1-180:1-184)
10 20 30 40 50 60
pF1KE3 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG
: :::.::.:.:::::::::.:.. . :...::::::: :::.. .:. .:.::::::
CCDS76 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVKRYEKVPLILVGNKVDL
:....::: :...:.::. :... : .::.::. .:.:: ::: . ::..::::: ::
CCDS76 QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDL
70 80 90 100 110 120
130 140 150 160 170
pF1KE3 EPEREVMSSEGRALAQEWGCPFMETSAKSKSMVDELFAEIVRQMNYSSL-----PEKQDQ
: : : ... ::. .: :..:::::... :.. : .::.. .: :...
CCDS76 AA-RTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQHKLRKLNPPDESGP
130 140 150 160 170
180
pF1KE3 CCTTCVVQ
: .:
CCDS76 GCMSCKCVLS
180
>>CCDS877.1 NRAS gene_id:4893|Hs108|chr1 (189 aa)
initn: 547 init1: 463 opt: 574 Z-score: 641.8 bits: 125.4 E(32554): 2e-29
Smith-Waterman score: 574; 47.6% identity (77.2% similar) in 189 aa overlap (1-182:1-188)
10 20 30 40 50 60
pF1KE3 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG
: :::.::.:.:::::::::.:.. . :...::::::: :::.. .:. .:.::::::
CCDS87 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVKRYEKVPLILVGNKVDL
:....::: :...:.::. :... :..:: ::. .:.:: ::: . ::..::::: ::
CCDS87 QEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCDL
70 80 90 100 110 120
130 140 150 160 170
pF1KE3 EPEREVMSSEGRALAQEWGCPFMETSAKSKSMVDELFAEIVR---QMNYSSLPEKQD--Q
: : : ..... ::. .: ::.:::::... :.. : .:: :. ...: ..: :
CCDS87 -PTRTVDTKQAHELAKSYGIPFIETSAKTRQGVEDAFYTLVREIRQYRMKKLNSSDDGTQ
130 140 150 160 170
180
pF1KE3 CCT--TCVVQ
: :::
CCDS87 GCMGLPCVVM
180
183 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 02:20:04 2016 done: Sun Nov 6 02:20:04 2016
Total Scan time: 1.730 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]