Result of FASTA (omim) for
pFN21AE3042
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3042, 182 aa
1>>>pF1KE3042 182 - 182 aa - 182 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.9294+/-0.000278; mu= 12.0769+/- 0.018
mean_var=109.8206+/-22.037, 0's: 0 Z-trim(121.1): 23 B-trim: 71 in 1/56
Lambda= 0.122386
statistics sampled from 37284 (37307) to 37284 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.767), E-opt: 0.2 (0.437), width: 16
Scan time: 5.920
The best scores are: opt bits E(85289)
NP_853531 (OMIM: 607886) CKLF-like MARVEL transmem ( 182) 1227 226.1 2.4e-59
XP_006721194 (OMIM: 607886) PREDICTED: CKLF-like M ( 182) 1227 226.1 2.4e-59
NP_653202 (OMIM: 607886) CKLF-like MARVEL transmem ( 182) 1227 226.1 2.4e-59
XP_011521163 (OMIM: 607886) PREDICTED: CKLF-like M ( 150) 726 137.6 9e-33
NP_612469 (OMIM: 607888) CKLF-like MARVEL transmem ( 156) 336 68.7 5e-12
XP_016876442 (OMIM: 607888) PREDICTED: CKLF-like M ( 156) 336 68.7 5e-12
XP_016876443 (OMIM: 607888) PREDICTED: CKLF-like M ( 156) 336 68.7 5e-12
NP_002659 (OMIM: 300112) proteolipid protein 2 [Ho ( 152) 217 47.7 1e-05
NP_001032365 (OMIM: 607888) CKLF-like MARVEL trans ( 125) 197 44.1 0.0001
NP_001275675 (OMIM: 607888) CKLF-like MARVEL trans ( 223) 184 42.0 0.00077
NP_852662 (OMIM: 607887) CKLF-like MARVEL transmem ( 208) 168 39.2 0.0052
XP_016878443 (OMIM: 607887) PREDICTED: CKLF-like M ( 221) 168 39.2 0.0054
NP_848933 (OMIM: 607887) CKLF-like MARVEL transmem ( 234) 168 39.2 0.0057
>>NP_853531 (OMIM: 607886) CKLF-like MARVEL transmembran (182 aa)
initn: 1227 init1: 1227 opt: 1227 Z-score: 1186.3 bits: 226.1 E(85289): 2.4e-59
Smith-Waterman score: 1227; 100.0% identity (100.0% similar) in 182 aa overlap (1-182:1-182)
10 20 30 40 50 60
pF1KE3 MWPPDPDPDPDPEPAGGSRPGPAVPGLRALLPARAFLCSLKGRLLLAESGLSFITFICYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_853 MWPPDPDPDPDPEPAGGSRPGPAVPGLRALLPARAFLCSLKGRLLLAESGLSFITFICYV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 ASSASAFLTAPLLEFLLALYFLFADAMQLNDKWQGLCWPMMDFLRCVTAALIYFAISITA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_853 ASSASAFLTAPLLEFLLALYFLFADAMQLNDKWQGLCWPMMDFLRCVTAALIYFAISITA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 IAKYSDGASKAAGVFGFFATIVFATDFYLIFNDVAKFLKQGDSADETTAHKTEEENSDSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_853 IAKYSDGASKAAGVFGFFATIVFATDFYLIFNDVAKFLKQGDSADETTAHKTEEENSDSD
130 140 150 160 170 180
pF1KE3 SD
::
NP_853 SD
>>XP_006721194 (OMIM: 607886) PREDICTED: CKLF-like MARVE (182 aa)
initn: 1227 init1: 1227 opt: 1227 Z-score: 1186.3 bits: 226.1 E(85289): 2.4e-59
Smith-Waterman score: 1227; 100.0% identity (100.0% similar) in 182 aa overlap (1-182:1-182)
10 20 30 40 50 60
pF1KE3 MWPPDPDPDPDPEPAGGSRPGPAVPGLRALLPARAFLCSLKGRLLLAESGLSFITFICYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MWPPDPDPDPDPEPAGGSRPGPAVPGLRALLPARAFLCSLKGRLLLAESGLSFITFICYV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 ASSASAFLTAPLLEFLLALYFLFADAMQLNDKWQGLCWPMMDFLRCVTAALIYFAISITA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ASSASAFLTAPLLEFLLALYFLFADAMQLNDKWQGLCWPMMDFLRCVTAALIYFAISITA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 IAKYSDGASKAAGVFGFFATIVFATDFYLIFNDVAKFLKQGDSADETTAHKTEEENSDSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IAKYSDGASKAAGVFGFFATIVFATDFYLIFNDVAKFLKQGDSADETTAHKTEEENSDSD
130 140 150 160 170 180
pF1KE3 SD
::
XP_006 SD
>>NP_653202 (OMIM: 607886) CKLF-like MARVEL transmembran (182 aa)
initn: 1227 init1: 1227 opt: 1227 Z-score: 1186.3 bits: 226.1 E(85289): 2.4e-59
Smith-Waterman score: 1227; 100.0% identity (100.0% similar) in 182 aa overlap (1-182:1-182)
10 20 30 40 50 60
pF1KE3 MWPPDPDPDPDPEPAGGSRPGPAVPGLRALLPARAFLCSLKGRLLLAESGLSFITFICYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 MWPPDPDPDPDPEPAGGSRPGPAVPGLRALLPARAFLCSLKGRLLLAESGLSFITFICYV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 ASSASAFLTAPLLEFLLALYFLFADAMQLNDKWQGLCWPMMDFLRCVTAALIYFAISITA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 ASSASAFLTAPLLEFLLALYFLFADAMQLNDKWQGLCWPMMDFLRCVTAALIYFAISITA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 IAKYSDGASKAAGVFGFFATIVFATDFYLIFNDVAKFLKQGDSADETTAHKTEEENSDSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 IAKYSDGASKAAGVFGFFATIVFATDFYLIFNDVAKFLKQGDSADETTAHKTEEENSDSD
130 140 150 160 170 180
pF1KE3 SD
::
NP_653 SD
>>XP_011521163 (OMIM: 607886) PREDICTED: CKLF-like MARVE (150 aa)
initn: 796 init1: 721 opt: 726 Z-score: 709.4 bits: 137.6 E(85289): 9e-33
Smith-Waterman score: 957; 82.4% identity (82.4% similar) in 182 aa overlap (1-182:1-150)
10 20 30 40 50 60
pF1KE3 MWPPDPDPDPDPEPAGGSRPGPAVPGLRALLPARAFLCSLKGRLLLAESGLSFITFICYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MWPPDPDPDPDPEPAGGSRPGPAVPGLRALLPARAFLCSLKGRLLLAESGLSFITFICYV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 ASSASAFLTAPLLEFLLALYFLFADAMQLNDKWQGLCWPMMDFLRCVTAALIYFAISITA
:::::::::::::::::::::::::::::::::::::::::
XP_011 ASSASAFLTAPLLEFLLALYFLFADAMQLNDKWQGLCWPMM-------------------
70 80 90 100
130 140 150 160 170 180
pF1KE3 IAKYSDGASKAAGVFGFFATIVFATDFYLIFNDVAKFLKQGDSADETTAHKTEEENSDSD
:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 -------------VFGFFATIVFATDFYLIFNDVAKFLKQGDSADETTAHKTEEENSDSD
110 120 130 140
pF1KE3 SD
::
XP_011 SD
150
>>NP_612469 (OMIM: 607888) CKLF-like MARVEL transmembran (156 aa)
initn: 204 init1: 204 opt: 336 Z-score: 337.0 bits: 68.7 E(85289): 5e-12
Smith-Waterman score: 336; 42.1% identity (73.6% similar) in 140 aa overlap (24-162:17-154)
10 20 30 40 50 60
pF1KE3 MWPPDPDPDPDPEPAGGSRPGPAVPGLRALLPARAFLCSLKGRLLLAESGLSFITFICYV
: :... .::: : :: :: .: .:..: :::..
NP_612 MLSARDRRDRHPEEGVVAELQGFAVDKAFLTSHKGILLETELALTLIIFICFT
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 ASSASAFLTAPLLEFLLALYFLFADAMQLNDKWQGLCWPMMDFLRCVTAALIYFAISITA
:: ::...: ::::...: ::: : : .... . :: .::::::.: .:....:..:
NP_612 AS-ISAYMAAALLEFFITLAFLFLYATQYYQRFDRINWPCLDFLRCVSAIIIFLVVSFAA
60 70 80 90 100 110
130 140 150 160 170
pF1KE3 IAKYSDGASKAAGVFGFFATIVFATDFYLIF-NDVAKFLKQGDSADETTAHKTEEENSDS
... :::. :: :::.. . .:: : . :. ...: .:::
NP_612 VTSR-DGAAIAAFVFGIILVSIFAYDAFKIYRTEMAPGASQGDQQ
120 130 140 150
180
pF1KE3 DSD
>>XP_016876442 (OMIM: 607888) PREDICTED: CKLF-like MARVE (156 aa)
initn: 204 init1: 204 opt: 336 Z-score: 337.0 bits: 68.7 E(85289): 5e-12
Smith-Waterman score: 336; 42.1% identity (73.6% similar) in 140 aa overlap (24-162:17-154)
10 20 30 40 50 60
pF1KE3 MWPPDPDPDPDPEPAGGSRPGPAVPGLRALLPARAFLCSLKGRLLLAESGLSFITFICYV
: :... .::: : :: :: .: .:..: :::..
XP_016 MLSARDRRDRHPEEGVVAELQGFAVDKAFLTSHKGILLETELALTLIIFICFT
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 ASSASAFLTAPLLEFLLALYFLFADAMQLNDKWQGLCWPMMDFLRCVTAALIYFAISITA
:: ::...: ::::...: ::: : : .... . :: .::::::.: .:....:..:
XP_016 AS-ISAYMAAALLEFFITLAFLFLYATQYYQRFDRINWPCLDFLRCVSAIIIFLVVSFAA
60 70 80 90 100 110
130 140 150 160 170
pF1KE3 IAKYSDGASKAAGVFGFFATIVFATDFYLIF-NDVAKFLKQGDSADETTAHKTEEENSDS
... :::. :: :::.. . .:: : . :. ...: .:::
XP_016 VTSR-DGAAIAAFVFGIILVSIFAYDAFKIYRTEMAPGASQGDQQ
120 130 140 150
180
pF1KE3 DSD
>>XP_016876443 (OMIM: 607888) PREDICTED: CKLF-like MARVE (156 aa)
initn: 204 init1: 204 opt: 336 Z-score: 337.0 bits: 68.7 E(85289): 5e-12
Smith-Waterman score: 336; 42.1% identity (73.6% similar) in 140 aa overlap (24-162:17-154)
10 20 30 40 50 60
pF1KE3 MWPPDPDPDPDPEPAGGSRPGPAVPGLRALLPARAFLCSLKGRLLLAESGLSFITFICYV
: :... .::: : :: :: .: .:..: :::..
XP_016 MLSARDRRDRHPEEGVVAELQGFAVDKAFLTSHKGILLETELALTLIIFICFT
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 ASSASAFLTAPLLEFLLALYFLFADAMQLNDKWQGLCWPMMDFLRCVTAALIYFAISITA
:: ::...: ::::...: ::: : : .... . :: .::::::.: .:....:..:
XP_016 AS-ISAYMAAALLEFFITLAFLFLYATQYYQRFDRINWPCLDFLRCVSAIIIFLVVSFAA
60 70 80 90 100 110
130 140 150 160 170
pF1KE3 IAKYSDGASKAAGVFGFFATIVFATDFYLIF-NDVAKFLKQGDSADETTAHKTEEENSDS
... :::. :: :::.. . .:: : . :. ...: .:::
XP_016 VTSR-DGAAIAAFVFGIILVSIFAYDAFKIYRTEMAPGASQGDQQ
120 130 140 150
180
pF1KE3 DSD
>>NP_002659 (OMIM: 300112) proteolipid protein 2 [Homo s (152 aa)
initn: 204 init1: 152 opt: 217 Z-score: 223.6 bits: 47.7 E(85289): 1e-05
Smith-Waterman score: 217; 31.8% identity (64.3% similar) in 129 aa overlap (23-151:8-133)
10 20 30 40 50 60
pF1KE3 MWPPDPDPDPDPEPAGGSRPGPAVPGLRALLPARAFLCSLKGRLLLAESGLSFITFICYV
..:: : : . :: ::.:: : .. .::.
NP_002 MADSERLSAPGCWA--ACTNFSRTRKGILLFAEIILCLVILICFS
10 20 30 40
70 80 90 100 110 120
pF1KE3 ASSASAFLTAPLLEFLLALYFLFADAMQLNDKWQGLCWPMMDFLRCVTAALIYFAISITA
::. . . . ..:..:: :. . .:. : . :: ::.: . ::..:. ::..
NP_002 ASTPG-YSSLSVIEMILAAIFFVVYMCDLHTKIPFINWPWSDFFRTLIAAILYLITSIVV
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE3 IAKYSDGASKAAGVFGFFATIVFATDFYLIFNDVAKFLKQGDSADETTAHKTEEENSDSD
... .. .. .:::.:..:: .:. : :. :
NP_002 LVERGNHSKIVAGVLGLIATCLFGYDAYVTFPVRQPRHTAAPTDPADGPV
110 120 130 140 150
pF1KE3 SD
>>NP_001032365 (OMIM: 607888) CKLF-like MARVEL transmemb (125 aa)
initn: 241 init1: 111 opt: 197 Z-score: 205.6 bits: 44.1 E(85289): 0.0001
Smith-Waterman score: 197; 37.4% identity (68.2% similar) in 107 aa overlap (24-130:17-121)
10 20 30 40 50 60
pF1KE3 MWPPDPDPDPDPEPAGGSRPGPAVPGLRALLPARAFLCSLKGRLLLAESGLSFITFICYV
: :... .::: : :: :: .: .:..: :::..
NP_001 MLSARDRRDRHPEEGVVAELQGFAVDKAFLTSHKGILLETELALTLIIFICFT
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 ASSASAFLTAPLLEFLLALYFLFADAMQLNDKWQGLCWPMMDFLRCVTAALIYFAISITA
:: ::...: ::::...: ::: : : .... . :: . : ... . : :..:
NP_001 AS-ISAYMAAALLEFFITLAFLFLYATQYYQRFDRINWPCLVFGIILVSIFAYDAFKIYR
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE3 IAKYSDGASKAAGVFGFFATIVFATDFYLIFNDVAKFLKQGDSADETTAHKTEEENSDSD
.... :::.
NP_001 -TEMAPGASQGDQQ
120
>>NP_001275675 (OMIM: 607888) CKLF-like MARVEL transmemb (223 aa)
initn: 270 init1: 107 opt: 184 Z-score: 189.9 bits: 42.0 E(85289): 0.00077
Smith-Waterman score: 184; 42.3% identity (70.5% similar) in 78 aa overlap (24-101:17-93)
10 20 30 40 50 60
pF1KE3 MWPPDPDPDPDPEPAGGSRPGPAVPGLRALLPARAFLCSLKGRLLLAESGLSFITFICYV
: :... .::: : :: :: .: .:..: :::..
NP_001 MLSARDRRDRHPEEGVVAELQGFAVDKAFLTSHKGILLETELALTLIIFICFT
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 ASSASAFLTAPLLEFLLALYFLFADAMQLNDKWQGLCWPMMDFLRCVTAALIYFAISITA
:: ::...: ::::...: ::: : : .... . :: .
NP_001 AS-ISAYMAAALLEFFITLAFLFLYATQYYQRFDRINWPCLLQGHGQSGGPHPLDLLSHS
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE3 IAKYSDGASKAAGVFGFFATIVFATDFYLIFNDVAKFLKQGDSADETTAHKTEEENSDSD
NP_001 AKVQPQPWPGLTPPGWHTPAAVPWVPAPAPGFWSWLLWFICFHSLGSSDFLRCVSAIIIF
120 130 140 150 160 170
182 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 17:04:44 2016 done: Mon Nov 7 17:04:45 2016
Total Scan time: 5.920 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]