Result of FASTA (omim) for
pFN21AE3039
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3039, 175 aa
1>>>pF1KE3039 175 - 175 aa - 175 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8939+/-0.000323; mu= 15.6878+/- 0.020
mean_var=63.1256+/-13.459, 0's: 0 Z-trim(115.8): 30 B-trim: 672 in 1/49
Lambda= 0.161425
statistics sampled from 26440 (26470) to 26440 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.664), E-opt: 0.2 (0.31), width: 16
Scan time: 5.770
The best scores are: opt bits E(85289)
NP_612419 (OMIM: 607890) CKLF-like MARVEL transmem ( 175) 1129 270.8 7.8e-73
XP_016861135 (OMIM: 607890) PREDICTED: CKLF-like M ( 179) 936 225.9 2.7e-59
XP_011531621 (OMIM: 607890) PREDICTED: CKLF-like M ( 151) 923 222.8 1.9e-58
NP_852137 (OMIM: 607890) CKLF-like MARVEL transmem ( 142) 734 178.8 3.3e-45
NP_852662 (OMIM: 607887) CKLF-like MARVEL transmem ( 208) 224 60.1 2.5e-09
XP_016878443 (OMIM: 607887) PREDICTED: CKLF-like M ( 221) 224 60.1 2.6e-09
NP_848933 (OMIM: 607887) CKLF-like MARVEL transmem ( 234) 224 60.1 2.8e-09
NP_002659 (OMIM: 300112) proteolipid protein 2 [Ho ( 152) 192 52.6 3.4e-07
XP_011521184 (OMIM: 607887) PREDICTED: CKLF-like M ( 179) 170 47.5 1.4e-05
NP_058647 (OMIM: 616074) chemokine-like factor iso ( 152) 161 45.3 5.1e-05
NP_060271 (OMIM: 607889) CKLF-like MARVEL transmem ( 183) 146 41.9 0.00067
NP_057077 (OMIM: 600340) plasmolipin [Homo sapiens ( 182) 144 41.4 0.00092
XP_016876443 (OMIM: 607888) PREDICTED: CKLF-like M ( 156) 141 40.7 0.0013
XP_016876442 (OMIM: 607888) PREDICTED: CKLF-like M ( 156) 141 40.7 0.0013
NP_612469 (OMIM: 607888) CKLF-like MARVEL transmem ( 156) 141 40.7 0.0013
NP_001035228 (OMIM: 616074) chemokine-like factor ( 113) 133 38.7 0.0037
NP_653202 (OMIM: 607886) CKLF-like MARVEL transmem ( 182) 133 38.9 0.0054
XP_006721194 (OMIM: 607886) PREDICTED: CKLF-like M ( 182) 133 38.9 0.0054
NP_853531 (OMIM: 607886) CKLF-like MARVEL transmem ( 182) 133 38.9 0.0054
NP_443725 (OMIM: 607884) CKLF-like MARVEL transmem ( 286) 134 39.2 0.0066
>>NP_612419 (OMIM: 607890) CKLF-like MARVEL transmembran (175 aa)
initn: 1129 init1: 1129 opt: 1129 Z-score: 1428.6 bits: 270.8 E(85289): 7.8e-73
Smith-Waterman score: 1129; 100.0% identity (100.0% similar) in 175 aa overlap (1-175:1-175)
10 20 30 40 50 60
pF1KE3 MSHGAGLVRTTCSSGSALGPGAGAAQPSASPLEGLLDLSYPRTHAALLKVAQMVTLLIAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 MSHGAGLVRTTCSSGSALGPGAGAAQPSASPLEGLLDLSYPRTHAALLKVAQMVTLLIAF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 ICVRSSLWTNYSAYSYFEVVTICDLIMILAFYLVHLFRFYRVLTCISWPLSELLHYLIGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 ICVRSSLWTNYSAYSYFEVVTICDLIMILAFYLVHLFRFYRVLTCISWPLSELLHYLIGT
70 80 90 100 110 120
130 140 150 160 170
pF1KE3 LLLLIASIVAASKSYNQSGLVAGAIFGFMATFLCMASIWLSYKISCVTQSTDAAV
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 LLLLIASIVAASKSYNQSGLVAGAIFGFMATFLCMASIWLSYKISCVTQSTDAAV
130 140 150 160 170
>>XP_016861135 (OMIM: 607890) PREDICTED: CKLF-like MARVE (179 aa)
initn: 927 init1: 927 opt: 936 Z-score: 1185.5 bits: 225.9 E(85289): 2.7e-59
Smith-Waterman score: 936; 96.1% identity (98.0% similar) in 152 aa overlap (1-152:1-152)
10 20 30 40 50 60
pF1KE3 MSHGAGLVRTTCSSGSALGPGAGAAQPSASPLEGLLDLSYPRTHAALLKVAQMVTLLIAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSHGAGLVRTTCSSGSALGPGAGAAQPSASPLEGLLDLSYPRTHAALLKVAQMVTLLIAF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 ICVRSSLWTNYSAYSYFEVVTICDLIMILAFYLVHLFRFYRVLTCISWPLSELLHYLIGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ICVRSSLWTNYSAYSYFEVVTICDLIMILAFYLVHLFRFYRVLTCISWPLSELLHYLIGT
70 80 90 100 110 120
130 140 150 160 170
pF1KE3 LLLLIASIVAASKSYNQSGLVAGAIFGFMATFLCMASIWLSYKISCVTQSTDAAV
::::::::::::::::::::::::. : ..:
XP_016 LLLLIASIVAASKSYNQSGLVAGAVRMFWGAFRNEFLFKMLIFFLMGEEKGLVSGAFPS
130 140 150 160 170
>>XP_011531621 (OMIM: 607890) PREDICTED: CKLF-like MARVE (151 aa)
initn: 923 init1: 923 opt: 923 Z-score: 1170.2 bits: 222.8 E(85289): 1.9e-58
Smith-Waterman score: 923; 100.0% identity (100.0% similar) in 144 aa overlap (1-144:1-144)
10 20 30 40 50 60
pF1KE3 MSHGAGLVRTTCSSGSALGPGAGAAQPSASPLEGLLDLSYPRTHAALLKVAQMVTLLIAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSHGAGLVRTTCSSGSALGPGAGAAQPSASPLEGLLDLSYPRTHAALLKVAQMVTLLIAF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 ICVRSSLWTNYSAYSYFEVVTICDLIMILAFYLVHLFRFYRVLTCISWPLSELLHYLIGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ICVRSSLWTNYSAYSYFEVVTICDLIMILAFYLVHLFRFYRVLTCISWPLSELLHYLIGT
70 80 90 100 110 120
130 140 150 160 170
pF1KE3 LLLLIASIVAASKSYNQSGLVAGAIFGFMATFLCMASIWLSYKISCVTQSTDAAV
::::::::::::::::::::::::
XP_011 LLLLIASIVAASKSYNQSGLVAGADNQSPLA
130 140 150
>>NP_852137 (OMIM: 607890) CKLF-like MARVEL transmembran (142 aa)
initn: 732 init1: 732 opt: 734 Z-score: 932.7 bits: 178.8 E(85289): 3.3e-45
Smith-Waterman score: 862; 81.1% identity (81.1% similar) in 175 aa overlap (1-175:1-142)
10 20 30 40 50 60
pF1KE3 MSHGAGLVRTTCSSGSALGPGAGAAQPSASPLEGLLDLSYPRTHAALLKVAQMVTLLIAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 MSHGAGLVRTTCSSGSALGPGAGAAQPSASPLEGLLDLSYPRTHAALLKVAQMVTLLIAF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 ICVRSSLWTNYSAYSYFEVVTICDLIMILAFYLVHLFRFYRVLTCISWPLSELLHYLIGT
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 ICVRSSLWTNYSAYSYFEVVTICDLIMILAFYLVHLFRFYRVLTCISWPLS---------
70 80 90 100 110
130 140 150 160 170
pF1KE3 LLLLIASIVAASKSYNQSGLVAGAIFGFMATFLCMASIWLSYKISCVTQSTDAAV
:::::::::::::::::::::::::::::::
NP_852 ------------------------IFGFMATFLCMASIWLSYKISCVTQSTDAAV
120 130 140
>>NP_852662 (OMIM: 607887) CKLF-like MARVEL transmembran (208 aa)
initn: 175 init1: 85 opt: 224 Z-score: 288.4 bits: 60.1 E(85289): 2.5e-09
Smith-Waterman score: 224; 29.2% identity (62.0% similar) in 171 aa overlap (13-172:15-185)
10 20 30 40 50
pF1KE3 MSHGAGLVRTTCSSGSALGPGAGAAQPSASP------LEGL-LDLSYPRTHAALLKVA
:: : .. ... ::.. : : :: : .: : . ::::
NP_852 MRSGEELDGFEGEASSTSMISGASSPYQPTTEPVSQRRGLAGLRCDPDYLRGALGRLKVA
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 QMVTLLIAFICVRSSLWTNYSAYSYFEVVTICDLIMILAFYLVHL-FRFYRVLTCISWPL
:.. ::::::... . . :: . :. ... . :. . . .. . :.: :
NP_852 QVILALIAFICIETIMACSPCEGLYFFEFVSCSAFVVTGVLLIMFSLNLHMRIPQINWNL
70 80 90 100 110 120
120 130 140 150 160
pF1KE3 SELLHYLIGTLLLLIASIVAASKSYNQSGLVAGAIFGFMATFLCMASIWLS---YKISCV
..:.. ....:..::::: :. .. .. .:..::::.:: .. .:. ...:
NP_852 TDLVNTGLSAFLFFIASIVLAALNHRAGAEIAAVIFGFLATAAYAVNTFLAVQKWRVSVR
130 140 150 160 170 180
170
pF1KE3 TQSTDAAV
:::.
NP_852 QQSTNDYIRARTESRDVDSRPEIQRLDT
190 200
>>XP_016878443 (OMIM: 607887) PREDICTED: CKLF-like MARVE (221 aa)
initn: 175 init1: 85 opt: 224 Z-score: 288.1 bits: 60.1 E(85289): 2.6e-09
Smith-Waterman score: 224; 29.2% identity (62.0% similar) in 171 aa overlap (13-172:15-185)
10 20 30 40 50
pF1KE3 MSHGAGLVRTTCSSGSALGPGAGAAQPSASP------LEGL-LDLSYPRTHAALLKVA
:: : .. ... ::.. : : :: : .: : . ::::
XP_016 MRSGEELDGFEGEASSTSMISGASSPYQPTTEPVSQRRGLAGLRCDPDYLRGALGRLKVA
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 QMVTLLIAFICVRSSLWTNYSAYSYFEVVTICDLIMILAFYLVHL-FRFYRVLTCISWPL
:.. ::::::... . . :: . :. ... . :. . . .. . :.: :
XP_016 QVILALIAFICIETIMACSPCEGLYFFEFVSCSAFVVTGVLLIMFSLNLHMRIPQINWNL
70 80 90 100 110 120
120 130 140 150 160
pF1KE3 SELLHYLIGTLLLLIASIVAASKSYNQSGLVAGAIFGFMATFLCMASIWLS---YKISCV
..:.. ....:..::::: :. .. .. .:..::::.:: .. .:. ...:
XP_016 TDLVNTGLSAFLFFIASIVLAALNHRAGAEIAAVIFGFLATAAYAVNTFLAVQKWRVSVR
130 140 150 160 170 180
170
pF1KE3 TQSTDAAV
:::.
XP_016 QQSTNDYIRARTESRDVDSRPEIQRLDTLNWKPNGHQQVKG
190 200 210 220
>>NP_848933 (OMIM: 607887) CKLF-like MARVEL transmembran (234 aa)
initn: 175 init1: 85 opt: 224 Z-score: 287.7 bits: 60.1 E(85289): 2.8e-09
Smith-Waterman score: 224; 29.2% identity (62.0% similar) in 171 aa overlap (13-172:15-185)
10 20 30 40 50
pF1KE3 MSHGAGLVRTTCSSGSALGPGAGAAQPSASP------LEGL-LDLSYPRTHAALLKVA
:: : .. ... ::.. : : :: : .: : . ::::
NP_848 MRSGEELDGFEGEASSTSMISGASSPYQPTTEPVSQRRGLAGLRCDPDYLRGALGRLKVA
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 QMVTLLIAFICVRSSLWTNYSAYSYFEVVTICDLIMILAFYLVHL-FRFYRVLTCISWPL
:.. ::::::... . . :: . :. ... . :. . . .. . :.: :
NP_848 QVILALIAFICIETIMACSPCEGLYFFEFVSCSAFVVTGVLLIMFSLNLHMRIPQINWNL
70 80 90 100 110 120
120 130 140 150 160
pF1KE3 SELLHYLIGTLLLLIASIVAASKSYNQSGLVAGAIFGFMATFLCMASIWLS---YKISCV
..:.. ....:..::::: :. .. .. .:..::::.:: .. .:. ...:
NP_848 TDLVNTGLSAFLFFIASIVLAALNHRAGAEIAAVIFGFLATAAYAVNTFLAVQKWRVSVR
130 140 150 160 170 180
170
pF1KE3 TQSTDAAV
:::.
NP_848 QQSTNDYIRARTESRDVDSRPEIQRLDTFSYSTNVTVRKKSPTNLLSLNHWQLA
190 200 210 220 230
>>NP_002659 (OMIM: 300112) proteolipid protein 2 [Homo s (152 aa)
initn: 201 init1: 97 opt: 192 Z-score: 250.1 bits: 52.6 E(85289): 3.4e-07
Smith-Waterman score: 192; 28.6% identity (65.1% similar) in 126 aa overlap (39-164:18-135)
10 20 30 40 50 60
pF1KE3 RTTCSSGSALGPGAGAAQPSASPLEGLLDLSYPRTHAALLKVAQMVTLLIAFICVRSSLW
.. ::. ..: :... :. .:: .:
NP_002 MADSERLSAPGCWAACTNFSRTRKGILLFAEIILCLVILICFSAST-
10 20 30 40
70 80 90 100 110 120
pF1KE3 TNYSAYSYFEVVTICDLIMILAFYLVHLFRFYRVLTCISWPLSELLHYLIGTLLLLIASI
.::. : .: .:. :..:.. .. . :.:: :.... ::...: ::.::
NP_002 PGYSSLSVIE------MILAAIFFVVYMCDLHTKIPFINWPWSDFFRTLIAAILYLITSI
50 60 70 80 90 100
130 140 150 160 170
pF1KE3 VAASKSYNQSGLVAGAIFGFMATFLCMASIWLSYKISCVTQSTDAAV
:. . :.: .::: ..:..:: : . .... .
NP_002 VVLVERGNHSKIVAG-VLGLIATCLFGYDAYVTFPVRQPRHTAAPTDPADGPV
110 120 130 140 150
>>XP_011521184 (OMIM: 607887) PREDICTED: CKLF-like MARVE (179 aa)
initn: 121 init1: 85 opt: 170 Z-score: 221.4 bits: 47.5 E(85289): 1.4e-05
Smith-Waterman score: 170; 26.8% identity (64.2% similar) in 123 aa overlap (54-172:34-156)
30 40 50 60 70 80
pF1KE3 AAQPSASPLEGLLDLSYPRTHAALLKVAQMVTLLIAFICVRSSLWTNYSAYSYFEVVTIC
. ::::::... . . :: . :
XP_011 GEELDGFEGEASSTSMISGASSPYQPTTEPILALIAFICIETIMACSPCEGLYFFEFVSC
10 20 30 40 50 60
90 100 110 120 130 140
pF1KE3 DLIMILAFYLVHL-FRFYRVLTCISWPLSELLHYLIGTLLLLIASIVAASKSYNQSGLVA
. ... . :. . . .. . :.: :..:.. ....:..::::: :. .. .. .:
XP_011 SAFVVTGVLLIMFSLNLHMRIPQINWNLTDLVNTGLSAFLFFIASIVLAALNHRAGAEIA
70 80 90 100 110 120
150 160 170
pF1KE3 GAIFGFMATFLCMASIWLS---YKISCVTQSTDAAV
..::::.:: .. .:. ...: :::.
XP_011 AVIFGFLATAAYAVNTFLAVQKWRVSVRQQSTNDYIRARTESRDVDSRPEIQRLDT
130 140 150 160 170
>>NP_058647 (OMIM: 616074) chemokine-like factor isoform (152 aa)
initn: 136 init1: 107 opt: 161 Z-score: 211.1 bits: 45.3 E(85289): 5.1e-05
Smith-Waterman score: 161; 27.0% identity (63.9% similar) in 122 aa overlap (42-163:18-130)
20 30 40 50 60 70
pF1KE3 CSSGSALGPGAGAAQPSASPLEGLLDLSYPRTHAALLKVAQMVTLLIAFICVRSSLWTNY
. :. .:..: :: . :: ... :
NP_058 MDNVQPKIKHRPFCFSVKGHVKMLRLALTVTSMTFFIIAQAP--EPY
10 20 30 40
80 90 100 110 120 130
pF1KE3 SAYSYFEVVTICDLIMILAFYLVHLFRFYRVLTCISWPLSELLHYLIGTLLLLIASIVAA
. . :::. .:: : :....:. :.. . ::: .... :. :...::.:..:
NP_058 IVITGFEVT------VILFFILLYVLRLDRLMKWLFWPLLDIINSLVTTVFMLIVSVLAL
50 60 70 80 90
140 150 160 170
pF1KE3 SKSYNQSGLVAGAIFGFMATFLCMASIWLSYKISCVTQSTDAAV
. . :.:..:..... :.:. : :.
NP_058 IPE-TTTLTVGGGVFALVTAVCCLADGALIYRKLLFNPSGPYQKKPVHEKKEVL
100 110 120 130 140 150
175 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 02:17:52 2016 done: Sun Nov 6 02:17:52 2016
Total Scan time: 5.770 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]