Result of FASTA (omim) for
pFN21AE3032
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3032, 161 aa
1>>>pF1KE3032 161 - 161 aa - 161 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.2899+/-0.00032; mu= 17.9298+/- 0.020
mean_var=59.2848+/-11.714, 0's: 0 Z-trim(115.8): 76 B-trim: 32 in 1/54
Lambda= 0.166572
statistics sampled from 26452 (26528) to 26452 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.705), E-opt: 0.2 (0.311), width: 16
Scan time: 5.370
The best scores are: opt bits E(85289)
NP_001138633 (OMIM: 615832) ubiquitin-conjugating ( 161) 1079 266.9 9.8e-72
NP_001271311 (OMIM: 612501) ubiquitin-conjugating ( 340) 566 144.0 2.2e-34
NP_001138807 (OMIM: 612501) ubiquitin-conjugating ( 359) 566 144.0 2.2e-34
NP_775740 (OMIM: 612501) ubiquitin-conjugating enz ( 375) 566 144.0 2.3e-34
XP_016878217 (OMIM: 612501) PREDICTED: ubiquitin-c ( 261) 398 103.5 2.5e-22
XP_005254845 (OMIM: 612501) PREDICTED: ubiquitin-c ( 296) 398 103.5 2.8e-22
XP_016878216 (OMIM: 612501) PREDICTED: ubiquitin-c ( 279) 271 73.0 4.1e-13
XP_016878215 (OMIM: 612501) PREDICTED: ubiquitin-c ( 298) 271 73.0 4.3e-13
XP_005254844 (OMIM: 612501) PREDICTED: ubiquitin-c ( 314) 271 73.0 4.5e-13
NP_871618 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 144 42.2 0.0004
NP_003331 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 144 42.2 0.0004
NP_871617 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 144 42.2 0.0004
NP_871620 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 144 42.2 0.0004
NP_871616 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 144 42.2 0.0004
NP_871615 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 144 42.2 0.0004
NP_003330 (OMIM: 602962) ubiquitin-conjugating enz ( 147) 144 42.2 0.0004
NP_871619 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 144 42.2 0.0004
NP_871621 (OMIM: 602963) ubiquitin-conjugating enz ( 148) 144 42.2 0.0004
NP_871622 (OMIM: 602963) ubiquitin-conjugating enz ( 149) 144 42.2 0.0004
NP_003329 (OMIM: 602961) ubiquitin-conjugating enz ( 147) 141 41.5 0.00066
XP_016865309 (OMIM: 602962) PREDICTED: ubiquitin-c ( 173) 138 40.8 0.0012
NP_003338 (OMIM: 603721) ubiquitin-conjugating enz ( 154) 127 38.1 0.007
NP_001243284 (OMIM: 603721) ubiquitin-conjugating ( 212) 127 38.3 0.0088
XP_011516251 (OMIM: 612506) PREDICTED: ubiquitin-c ( 193) 126 38.0 0.0097
>>NP_001138633 (OMIM: 615832) ubiquitin-conjugating enzy (161 aa)
initn: 1079 init1: 1079 opt: 1079 Z-score: 1408.9 bits: 266.9 E(85289): 9.8e-72
Smith-Waterman score: 1079; 100.0% identity (100.0% similar) in 161 aa overlap (1-161:1-161)
10 20 30 40 50 60
pF1KE3 MKELQDIARLSDRFISVELVDESLFDWNVKLHQVDKDSVLWQDMKETNTEFILLNLTFPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKELQDIARLSDRFISVELVDESLFDWNVKLHQVDKDSVLWQDMKETNTEFILLNLTFPD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 NFPFSPPFMRVLSPRLENGYVLDGGAICMELLTPRGWSSAYTVEAVMRQFAASLVKGQGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NFPFSPPFMRVLSPRLENGYVLDGGAICMELLTPRGWSSAYTVEAVMRQFAASLVKGQGR
70 80 90 100 110 120
130 140 150 160
pF1KE3 ICRKAGKSKKSFSRKEAEATFKSLVKTHEKYGWVTPPVSDG
:::::::::::::::::::::::::::::::::::::::::
NP_001 ICRKAGKSKKSFSRKEAEATFKSLVKTHEKYGWVTPPVSDG
130 140 150 160
>>NP_001271311 (OMIM: 612501) ubiquitin-conjugating enzy (340 aa)
initn: 590 init1: 326 opt: 566 Z-score: 738.4 bits: 144.0 E(85289): 2.2e-34
Smith-Waterman score: 566; 50.6% identity (78.6% similar) in 168 aa overlap (1-161:175-340)
10 20
pF1KE3 MKELQDIARLSDR---FISVELVDESLFDW
::::.:: : .. . ::::...::.::
NP_001 LAILEKIRKTQRQDHLNGAVSGSVQASDRLMKELRDIYRSQSYKTGIYSVELINDSLYDW
150 160 170 180 190 200
30 40 50 60 70 80
pF1KE3 NVKLHQVDKDSVLWQDMK----ETNTEFILLNLTFPDNFPFSPPFMRVLSPRLENGYVLD
.:::..:: :: : .:.. . . :.::::..: :::::.:::.::. : : .::::
NP_001 HVKLQKVDPDSPLHSDLQILKEKEGIEYILLNFSFKDNFPFDPPFVRVVLPVLSGGYVLG
210 220 230 240 250 260
90 100 110 120 130 140
pF1KE3 GGAICMELLTPRGWSSAYTVEAVMRQFAASLVKGQGRICRKAGKSKKSFSRKEAEATFKS
:::.:::::: .::::::..:.:. :. :.::::..:. . : .:.... .:. ...:
NP_001 GGALCMELLTKQGWSSAYSIESVIMQINATLVKGKARV--QFGANKNQYNLARAQQSYNS
270 280 290 300 310 320
150 160
pF1KE3 LVKTHEKYGWVTPPVSDG
.:. ::: :: ::: ::
NP_001 IVQIHEKNGWYTPPKEDG
330 340
>>NP_001138807 (OMIM: 612501) ubiquitin-conjugating enzy (359 aa)
initn: 590 init1: 326 opt: 566 Z-score: 738.1 bits: 144.0 E(85289): 2.2e-34
Smith-Waterman score: 566; 50.6% identity (78.6% similar) in 168 aa overlap (1-161:194-359)
10 20
pF1KE3 MKELQDIARLSDR---FISVELVDESLFDW
::::.:: : .. . ::::...::.::
NP_001 LAILEKIRKTQRQDHLNGAVSGSVQASDRLMKELRDIYRSQSYKTGIYSVELINDSLYDW
170 180 190 200 210 220
30 40 50 60 70 80
pF1KE3 NVKLHQVDKDSVLWQDMK----ETNTEFILLNLTFPDNFPFSPPFMRVLSPRLENGYVLD
.:::..:: :: : .:.. . . :.::::..: :::::.:::.::. : : .::::
NP_001 HVKLQKVDPDSPLHSDLQILKEKEGIEYILLNFSFKDNFPFDPPFVRVVLPVLSGGYVLG
230 240 250 260 270 280
90 100 110 120 130 140
pF1KE3 GGAICMELLTPRGWSSAYTVEAVMRQFAASLVKGQGRICRKAGKSKKSFSRKEAEATFKS
:::.:::::: .::::::..:.:. :. :.::::..:. . : .:.... .:. ...:
NP_001 GGALCMELLTKQGWSSAYSIESVIMQINATLVKGKARV--QFGANKNQYNLARAQQSYNS
290 300 310 320 330 340
150 160
pF1KE3 LVKTHEKYGWVTPPVSDG
.:. ::: :: ::: ::
NP_001 IVQIHEKNGWYTPPKEDG
350
>>NP_775740 (OMIM: 612501) ubiquitin-conjugating enzyme (375 aa)
initn: 590 init1: 326 opt: 566 Z-score: 737.9 bits: 144.0 E(85289): 2.3e-34
Smith-Waterman score: 566; 50.6% identity (78.6% similar) in 168 aa overlap (1-161:210-375)
10 20
pF1KE3 MKELQDIARLSDR---FISVELVDESLFDW
::::.:: : .. . ::::...::.::
NP_775 LAILEKIRKTQRQDHLNGAVSGSVQASDRLMKELRDIYRSQSYKTGIYSVELINDSLYDW
180 190 200 210 220 230
30 40 50 60 70 80
pF1KE3 NVKLHQVDKDSVLWQDMK----ETNTEFILLNLTFPDNFPFSPPFMRVLSPRLENGYVLD
.:::..:: :: : .:.. . . :.::::..: :::::.:::.::. : : .::::
NP_775 HVKLQKVDPDSPLHSDLQILKEKEGIEYILLNFSFKDNFPFDPPFVRVVLPVLSGGYVLG
240 250 260 270 280 290
90 100 110 120 130 140
pF1KE3 GGAICMELLTPRGWSSAYTVEAVMRQFAASLVKGQGRICRKAGKSKKSFSRKEAEATFKS
:::.:::::: .::::::..:.:. :. :.::::..:. . : .:.... .:. ...:
NP_775 GGALCMELLTKQGWSSAYSIESVIMQINATLVKGKARV--QFGANKNQYNLARAQQSYNS
300 310 320 330 340 350
150 160
pF1KE3 LVKTHEKYGWVTPPVSDG
.:. ::: :: ::: ::
NP_775 IVQIHEKNGWYTPPKEDG
360 370
>>XP_016878217 (OMIM: 612501) PREDICTED: ubiquitin-conju (261 aa)
initn: 428 init1: 294 opt: 398 Z-score: 521.7 bits: 103.5 E(85289): 2.5e-22
Smith-Waterman score: 398; 53.9% identity (81.4% similar) in 102 aa overlap (60-161:162-261)
30 40 50 60 70 80
pF1KE3 KLHQVDKDSVLWQDMKETNTEFILLNLTFPDNFPFSPPFMRVLSPRLENGYVLDGGAICM
:::::.:::.::. : : .:::: :::.::
XP_016 GKKSEDEGIEKENLAILEKIRKTQRQDHLNDNFPFDPPFVRVVLPVLSGGYVLGGGALCM
140 150 160 170 180 190
90 100 110 120 130 140
pF1KE3 ELLTPRGWSSAYTVEAVMRQFAASLVKGQGRICRKAGKSKKSFSRKEAEATFKSLVKTHE
:::: .::::::..:.:. :. :.::::..:. . : .:.... .:. ...:.:. ::
XP_016 ELLTKQGWSSAYSIESVIMQINATLVKGKARV--QFGANKNQYNLARAQQSYNSIVQIHE
200 210 220 230 240
150 160
pF1KE3 KYGWVTPPVSDG
: :: ::: ::
XP_016 KNGWYTPPKEDG
250 260
>>XP_005254845 (OMIM: 612501) PREDICTED: ubiquitin-conju (296 aa)
initn: 428 init1: 294 opt: 398 Z-score: 521.0 bits: 103.5 E(85289): 2.8e-22
Smith-Waterman score: 398; 53.9% identity (81.4% similar) in 102 aa overlap (60-161:197-296)
30 40 50 60 70 80
pF1KE3 KLHQVDKDSVLWQDMKETNTEFILLNLTFPDNFPFSPPFMRVLSPRLENGYVLDGGAICM
:::::.:::.::. : : .:::: :::.::
XP_005 GKKSEDEGIEKENLAILEKIRKTQRQDHLNDNFPFDPPFVRVVLPVLSGGYVLGGGALCM
170 180 190 200 210 220
90 100 110 120 130 140
pF1KE3 ELLTPRGWSSAYTVEAVMRQFAASLVKGQGRICRKAGKSKKSFSRKEAEATFKSLVKTHE
:::: .::::::..:.:. :. :.::::..:. . : .:.... .:. ...:.:. ::
XP_005 ELLTKQGWSSAYSIESVIMQINATLVKGKARV--QFGANKNQYNLARAQQSYNSIVQIHE
230 240 250 260 270 280
150 160
pF1KE3 KYGWVTPPVSDG
: :: ::: ::
XP_005 KNGWYTPPKEDG
290
>>XP_016878216 (OMIM: 612501) PREDICTED: ubiquitin-conju (279 aa)
initn: 283 init1: 145 opt: 271 Z-score: 356.4 bits: 73.0 E(85289): 4.1e-13
Smith-Waterman score: 271; 50.0% identity (76.1% similar) in 88 aa overlap (1-81:175-262)
10 20
pF1KE3 MKELQDIARLSDR---FISVELVDESLFDW
::::.:: : .. . ::::...::.::
XP_016 LAILEKIRKTQRQDHLNGAVSGSVQASDRLMKELRDIYRSQSYKTGIYSVELINDSLYDW
150 160 170 180 190 200
30 40 50 60 70 80
pF1KE3 NVKLHQVDKDSVLWQDMK----ETNTEFILLNLTFPDNFPFSPPFMRVLSPRLENGYVLD
.:::..:: :: : .:.. . . :.::::..: :::::.:::.::. : : .: :
XP_016 HVKLQKVDPDSPLHSDLQILKEKEGIEYILLNFSFKDNFPFDPPFVRVVLPVLSGGLVHP
210 220 230 240 250 260
90 100 110 120 130 140
pF1KE3 GGAICMELLTPRGWSSAYTVEAVMRQFAASLVKGQGRICRKAGKSKKSFSRKEAEATFKS
XP_016 SKGRWLNVLTVVCLD
270
>>XP_016878215 (OMIM: 612501) PREDICTED: ubiquitin-conju (298 aa)
initn: 283 init1: 145 opt: 271 Z-score: 356.0 bits: 73.0 E(85289): 4.3e-13
Smith-Waterman score: 271; 50.0% identity (76.1% similar) in 88 aa overlap (1-81:194-281)
10 20
pF1KE3 MKELQDIARLSDR---FISVELVDESLFDW
::::.:: : .. . ::::...::.::
XP_016 LAILEKIRKTQRQDHLNGAVSGSVQASDRLMKELRDIYRSQSYKTGIYSVELINDSLYDW
170 180 190 200 210 220
30 40 50 60 70 80
pF1KE3 NVKLHQVDKDSVLWQDMK----ETNTEFILLNLTFPDNFPFSPPFMRVLSPRLENGYVLD
.:::..:: :: : .:.. . . :.::::..: :::::.:::.::. : : .: :
XP_016 HVKLQKVDPDSPLHSDLQILKEKEGIEYILLNFSFKDNFPFDPPFVRVVLPVLSGGLVHP
230 240 250 260 270 280
90 100 110 120 130 140
pF1KE3 GGAICMELLTPRGWSSAYTVEAVMRQFAASLVKGQGRICRKAGKSKKSFSRKEAEATFKS
XP_016 SKGRWLNVLTVVCLD
290
>>XP_005254844 (OMIM: 612501) PREDICTED: ubiquitin-conju (314 aa)
initn: 283 init1: 145 opt: 271 Z-score: 355.7 bits: 73.0 E(85289): 4.5e-13
Smith-Waterman score: 271; 50.0% identity (76.1% similar) in 88 aa overlap (1-81:210-297)
10 20
pF1KE3 MKELQDIARLSDR---FISVELVDESLFDW
::::.:: : .. . ::::...::.::
XP_005 LAILEKIRKTQRQDHLNGAVSGSVQASDRLMKELRDIYRSQSYKTGIYSVELINDSLYDW
180 190 200 210 220 230
30 40 50 60 70 80
pF1KE3 NVKLHQVDKDSVLWQDMK----ETNTEFILLNLTFPDNFPFSPPFMRVLSPRLENGYVLD
.:::..:: :: : .:.. . . :.::::..: :::::.:::.::. : : .: :
XP_005 HVKLQKVDPDSPLHSDLQILKEKEGIEYILLNFSFKDNFPFDPPFVRVVLPVLSGGLVHP
240 250 260 270 280 290
90 100 110 120 130 140
pF1KE3 GGAICMELLTPRGWSSAYTVEAVMRQFAASLVKGQGRICRKAGKSKKSFSRKEAEATFKS
XP_005 SKGRWLNVLTVVCLD
300 310
>>NP_871618 (OMIM: 602963) ubiquitin-conjugating enzyme (147 aa)
initn: 116 init1: 67 opt: 144 Z-score: 195.0 bits: 42.2 E(85289): 0.0004
Smith-Waterman score: 144; 25.5% identity (60.4% similar) in 106 aa overlap (2-107:8-103)
10 20 30 40 50
pF1KE3 MKELQDIARLSDRFISVELVDESLFDWNVKLHQVDKDSVLWQDMKETNTEFILL
:::.:.:: :. : ...: :.. ... . . . ..:
NP_871 MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQA--------TIMGPNDSPYQGGVFFL
10 20 30 40 50
60 70 80 90 100 110
pF1KE3 NLTFPDNFPFSPPFMRVLSPRLENGYVLDGGAICMELLTPRGWSSAYTVEAVMRQFAASL
.. :: ..::.:: . ... :. . . ..:.::...: . :: : :. :.
NP_871 TIHFPTDYPFKPPKV-AFTTRIYHPNINSNGSICLDILRSQ-WSPALTISKVLLSICSLL
60 70 80 90 100 110
120 130 140 150 160
pF1KE3 VKGQGRICRKAGKSKKSFSRKEAEATFKSLVKTHEKYGWVTPPVSDG
NP_871 CDPNPDDPLVPEIARIYKTDRDKYNRISREWTQKYAM
120 130 140
161 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 14:40:01 2016 done: Mon Nov 7 14:40:01 2016
Total Scan time: 5.370 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]