Result of FASTA (omim) for
pFN21AE3030
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3030, 156 aa
1>>>pF1KE3030 156 - 156 aa - 156 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3329+/-0.00039; mu= 13.0500+/- 0.024
mean_var=131.2146+/-29.174, 0's: 0 Z-trim(115.4): 308 B-trim: 0 in 0/50
Lambda= 0.111965
statistics sampled from 25484 (25909) to 25484 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.668), E-opt: 0.2 (0.304), width: 16
Scan time: 4.950
The best scores are: opt bits E(85289)
NP_002306 (OMIM: 186921) rhombotin-1 isoform a [Ho ( 156) 1124 192.2 2.8e-49
NP_001257357 (OMIM: 186921) rhombotin-1 isoform b ( 155) 1113 190.4 9.7e-49
XP_006718291 (OMIM: 186921) PREDICTED: rhombotin-1 ( 193) 1072 184.0 1.1e-46
XP_011518400 (OMIM: 186921) PREDICTED: rhombotin-1 ( 145) 1049 180.1 1.2e-45
XP_011518401 (OMIM: 186921) PREDICTED: rhombotin-1 ( 145) 1049 180.1 1.2e-45
NP_001230540 (OMIM: 180386) LIM domain only protei ( 156) 962 166.1 2.1e-41
NP_001230541 (OMIM: 180386) LIM domain only protei ( 163) 951 164.3 7.5e-41
XP_006719173 (OMIM: 180386) PREDICTED: LIM domain ( 145) 948 163.8 9.8e-41
XP_006719174 (OMIM: 180386) PREDICTED: LIM domain ( 145) 948 163.8 9.8e-41
XP_011519064 (OMIM: 180386) PREDICTED: LIM domain ( 145) 948 163.8 9.8e-41
NP_061110 (OMIM: 180386) LIM domain only protein 3 ( 145) 948 163.8 9.8e-41
XP_011519065 (OMIM: 180386) PREDICTED: LIM domain ( 145) 948 163.8 9.8e-41
NP_001230538 (OMIM: 180386) LIM domain only protei ( 145) 948 163.8 9.8e-41
NP_001001395 (OMIM: 180386) LIM domain only protei ( 145) 948 163.8 9.8e-41
NP_001230539 (OMIM: 180386) LIM domain only protei ( 145) 948 163.8 9.8e-41
XP_005252978 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158) 578 104.0 1e-22
NP_001135788 (OMIM: 180385) rhombotin-2 isoform 2 ( 158) 578 104.0 1e-22
XP_016873218 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158) 578 104.0 1e-22
NP_001135787 (OMIM: 180385) rhombotin-2 isoform 2 ( 158) 578 104.0 1e-22
XP_016873217 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158) 578 104.0 1e-22
XP_016873221 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158) 578 104.0 1e-22
XP_016873219 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158) 578 104.0 1e-22
XP_016873222 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158) 578 104.0 1e-22
XP_016873216 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158) 578 104.0 1e-22
XP_016873220 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158) 578 104.0 1e-22
NP_005565 (OMIM: 180385) rhombotin-2 isoform 1 [Ho ( 227) 578 104.2 1.3e-22
NP_006760 (OMIM: 603129) LIM domain transcription ( 165) 554 100.2 1.5e-21
XP_005271348 (OMIM: 603129) PREDICTED: LIM domain ( 165) 554 100.2 1.5e-21
XP_011518402 (OMIM: 186921) PREDICTED: rhombotin-1 ( 122) 552 99.7 1.6e-21
XP_016875132 (OMIM: 180386) PREDICTED: LIM domain ( 125) 469 86.3 1.8e-17
NP_001230542 (OMIM: 180386) LIM domain only protei ( 167) 469 86.5 2.1e-17
XP_005245407 (OMIM: 606066) PREDICTED: LIM/homeobo ( 336) 440 82.2 8.1e-16
XP_016857338 (OMIM: 606066) PREDICTED: LIM/homeobo ( 378) 440 82.3 8.7e-16
NP_001014434 (OMIM: 606066) LIM/homeobox protein L ( 388) 440 82.3 8.9e-16
NP_203129 (OMIM: 262700,602146) LIM/homeobox prote ( 390) 440 82.3 8.9e-16
NP_064589 (OMIM: 606066) LIM/homeobox protein Lhx9 ( 397) 440 82.3 9e-16
XP_011508083 (OMIM: 606066) PREDICTED: LIM/homeobo ( 403) 440 82.3 9.1e-16
XP_006717386 (OMIM: 603759) PREDICTED: LIM/homeobo ( 314) 430 80.5 2.4e-15
NP_004780 (OMIM: 603759) LIM/homeobox protein Lhx2 ( 406) 430 80.7 2.8e-15
XP_016870657 (OMIM: 221750,600577) PREDICTED: LIM/ ( 373) 406 76.8 3.9e-14
XP_005263467 (OMIM: 221750,600577) PREDICTED: LIM/ ( 386) 406 76.8 4e-14
NP_835258 (OMIM: 221750,600577) LIM/homeobox prote ( 397) 406 76.8 4e-14
NP_055379 (OMIM: 221750,600577) LIM/homeobox prote ( 402) 406 76.8 4.1e-14
NP_005559 (OMIM: 601999) LIM/homeobox protein Lhx1 ( 406) 379 72.4 8.4e-13
XP_011507842 (OMIM: 600298) PREDICTED: LIM homeobo ( 279) 370 70.8 1.8e-12
NP_665804 (OMIM: 609481) insulin gene enhancer pro ( 359) 370 70.9 2.1e-12
NP_796372 (OMIM: 600298) LIM homeobox transcriptio ( 382) 370 71.0 2.2e-12
NP_001167540 (OMIM: 600298) LIM homeobox transcrip ( 382) 370 71.0 2.2e-12
XP_016877994 (OMIM: 609481) PREDICTED: insulin gen ( 534) 370 71.1 2.7e-12
NP_002307 (OMIM: 161200,602575) LIM homeobox trans ( 395) 367 70.5 3.2e-12
>>NP_002306 (OMIM: 186921) rhombotin-1 isoform a [Homo s (156 aa)
initn: 1124 init1: 1124 opt: 1124 Z-score: 1005.6 bits: 192.2 E(85289): 2.8e-49
Smith-Waterman score: 1124; 100.0% identity (100.0% similar) in 156 aa overlap (1-156:1-156)
10 20 30 40 50 60
pF1KE3 MMVLDKEDGVPMLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MMVLDKEDGVPMLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 VGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCN
70 80 90 100 110 120
130 140 150
pF1KE3 QRFCVGDKFFLKNNMILCQMDYEEGQLNGTFESQVQ
::::::::::::::::::::::::::::::::::::
NP_002 QRFCVGDKFFLKNNMILCQMDYEEGQLNGTFESQVQ
130 140 150
>>NP_001257357 (OMIM: 186921) rhombotin-1 isoform b [Hom (155 aa)
initn: 1113 init1: 1113 opt: 1113 Z-score: 996.1 bits: 190.4 E(85289): 9.7e-49
Smith-Waterman score: 1113; 99.4% identity (100.0% similar) in 155 aa overlap (2-156:1-155)
10 20 30 40 50 60
pF1KE3 MMVLDKEDGVPMLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGE
::::.::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVLDQEDGVPMLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGE
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 VGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCN
60 70 80 90 100 110
130 140 150
pF1KE3 QRFCVGDKFFLKNNMILCQMDYEEGQLNGTFESQVQ
::::::::::::::::::::::::::::::::::::
NP_001 QRFCVGDKFFLKNNMILCQMDYEEGQLNGTFESQVQ
120 130 140 150
>>XP_006718291 (OMIM: 186921) PREDICTED: rhombotin-1 iso (193 aa)
initn: 1072 init1: 1072 opt: 1072 Z-score: 959.2 bits: 184.0 E(85289): 1.1e-46
Smith-Waterman score: 1072; 100.0% identity (100.0% similar) in 148 aa overlap (9-156:46-193)
10 20 30
pF1KE3 MMVLDKEDGVPMLSVQPKGKQKGCAGCNRKIKDRYLLK
::::::::::::::::::::::::::::::
XP_006 GEPRGRAWSDLELGEVDVLGWKSGLGGAHWGVPMLSVQPKGKQKGCAGCNRKIKDRYLLK
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE3 ALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAF
80 90 100 110 120 130
100 110 120 130 140 150
pF1KE3 EMVMRARDNVYHLDCFACQLCNQRFCVGDKFFLKNNMILCQMDYEEGQLNGTFESQVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EMVMRARDNVYHLDCFACQLCNQRFCVGDKFFLKNNMILCQMDYEEGQLNGTFESQVQ
140 150 160 170 180 190
>>XP_011518400 (OMIM: 186921) PREDICTED: rhombotin-1 iso (145 aa)
initn: 1049 init1: 1049 opt: 1049 Z-score: 940.5 bits: 180.1 E(85289): 1.2e-45
Smith-Waterman score: 1049; 100.0% identity (100.0% similar) in 145 aa overlap (12-156:1-145)
10 20 30 40 50 60
pF1KE3 MMVLDKEDGVPMLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGE
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGE
10 20 30 40
70 80 90 100 110 120
pF1KE3 VGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCN
50 60 70 80 90 100
130 140 150
pF1KE3 QRFCVGDKFFLKNNMILCQMDYEEGQLNGTFESQVQ
::::::::::::::::::::::::::::::::::::
XP_011 QRFCVGDKFFLKNNMILCQMDYEEGQLNGTFESQVQ
110 120 130 140
>>XP_011518401 (OMIM: 186921) PREDICTED: rhombotin-1 iso (145 aa)
initn: 1049 init1: 1049 opt: 1049 Z-score: 940.5 bits: 180.1 E(85289): 1.2e-45
Smith-Waterman score: 1049; 100.0% identity (100.0% similar) in 145 aa overlap (12-156:1-145)
10 20 30 40 50 60
pF1KE3 MMVLDKEDGVPMLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGE
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGE
10 20 30 40
70 80 90 100 110 120
pF1KE3 VGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCN
50 60 70 80 90 100
130 140 150
pF1KE3 QRFCVGDKFFLKNNMILCQMDYEEGQLNGTFESQVQ
::::::::::::::::::::::::::::::::::::
XP_011 QRFCVGDKFFLKNNMILCQMDYEEGQLNGTFESQVQ
110 120 130 140
>>NP_001230540 (OMIM: 180386) LIM domain only protein 3 (156 aa)
initn: 1052 init1: 948 opt: 962 Z-score: 864.2 bits: 166.1 E(85289): 2.1e-41
Smith-Waterman score: 962; 85.3% identity (91.0% similar) in 156 aa overlap (1-156:1-156)
10 20 30 40 50 60
pF1KE3 MMVLDKEDGVPMLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGE
:. .: :. :::::: : :::::::::::::::::::::::::::::::::::::::
NP_001 MQKKEKSFGIQMLSVQPDTKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 VGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCN
:::::::::::::::::::::::.::::::::::::::::::::.:::::::::::::::
NP_001 VGSTLYTKANLILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCN
70 80 90 100 110 120
130 140 150
pF1KE3 QRFCVGDKFFLKNNMILCQMDYEEGQLNGTFESQVQ
::::::::::::::::::: ::::: .. . ::.
NP_001 QRFCVGDKFFLKNNMILCQTDYEEGLMKEGYAPQVR
130 140 150
>>NP_001230541 (OMIM: 180386) LIM domain only protein 3 (163 aa)
initn: 1040 init1: 948 opt: 951 Z-score: 854.4 bits: 164.3 E(85289): 7.5e-41
Smith-Waterman score: 951; 88.4% identity (93.2% similar) in 147 aa overlap (10-156:17-163)
10 20 30 40 50
pF1KE3 MMVLDKEDGVPMLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCAC
. :::::: : ::::::::::::::::::::::::::::::::
NP_001 MLMEGGRAAAARNVSSIQMLSVQPDTKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCAC
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 CDCRLGEVGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDC
::::::::::::::::::::::::::::::.::::::::::::::::::::.::::::::
NP_001 CDCRLGEVGSTLYTKANLILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDC
70 80 90 100 110 120
120 130 140 150
pF1KE3 FACQLCNQRFCVGDKFFLKNNMILCQMDYEEGQLNGTFESQVQ
:::::::::::::::::::::::::: ::::: .. . ::.
NP_001 FACQLCNQRFCVGDKFFLKNNMILCQTDYEEGLMKEGYAPQVR
130 140 150 160
>>XP_006719173 (OMIM: 180386) PREDICTED: LIM domain only (145 aa)
initn: 1052 init1: 948 opt: 948 Z-score: 852.3 bits: 163.8 E(85289): 9.8e-41
Smith-Waterman score: 948; 89.7% identity (93.8% similar) in 145 aa overlap (12-156:1-145)
10 20 30 40 50 60
pF1KE3 MMVLDKEDGVPMLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGE
:::::: : :::::::::::::::::::::::::::::::::::::::
XP_006 MLSVQPDTKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGE
10 20 30 40
70 80 90 100 110 120
pF1KE3 VGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCN
:::::::::::::::::::::::.::::::::::::::::::::.:::::::::::::::
XP_006 VGSTLYTKANLILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCN
50 60 70 80 90 100
130 140 150
pF1KE3 QRFCVGDKFFLKNNMILCQMDYEEGQLNGTFESQVQ
::::::::::::::::::: ::::: .. . ::.
XP_006 QRFCVGDKFFLKNNMILCQTDYEEGLMKEGYAPQVR
110 120 130 140
>>XP_006719174 (OMIM: 180386) PREDICTED: LIM domain only (145 aa)
initn: 1052 init1: 948 opt: 948 Z-score: 852.3 bits: 163.8 E(85289): 9.8e-41
Smith-Waterman score: 948; 89.7% identity (93.8% similar) in 145 aa overlap (12-156:1-145)
10 20 30 40 50 60
pF1KE3 MMVLDKEDGVPMLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGE
:::::: : :::::::::::::::::::::::::::::::::::::::
XP_006 MLSVQPDTKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGE
10 20 30 40
70 80 90 100 110 120
pF1KE3 VGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCN
:::::::::::::::::::::::.::::::::::::::::::::.:::::::::::::::
XP_006 VGSTLYTKANLILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCN
50 60 70 80 90 100
130 140 150
pF1KE3 QRFCVGDKFFLKNNMILCQMDYEEGQLNGTFESQVQ
::::::::::::::::::: ::::: .. . ::.
XP_006 QRFCVGDKFFLKNNMILCQTDYEEGLMKEGYAPQVR
110 120 130 140
>>XP_011519064 (OMIM: 180386) PREDICTED: LIM domain only (145 aa)
initn: 1052 init1: 948 opt: 948 Z-score: 852.3 bits: 163.8 E(85289): 9.8e-41
Smith-Waterman score: 948; 89.7% identity (93.8% similar) in 145 aa overlap (12-156:1-145)
10 20 30 40 50 60
pF1KE3 MMVLDKEDGVPMLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGE
:::::: : :::::::::::::::::::::::::::::::::::::::
XP_011 MLSVQPDTKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGE
10 20 30 40
70 80 90 100 110 120
pF1KE3 VGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCN
:::::::::::::::::::::::.::::::::::::::::::::.:::::::::::::::
XP_011 VGSTLYTKANLILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCN
50 60 70 80 90 100
130 140 150
pF1KE3 QRFCVGDKFFLKNNMILCQMDYEEGQLNGTFESQVQ
::::::::::::::::::: ::::: .. . ::.
XP_011 QRFCVGDKFFLKNNMILCQTDYEEGLMKEGYAPQVR
110 120 130 140
156 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 04:56:52 2016 done: Sun Nov 6 04:56:53 2016
Total Scan time: 4.950 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]