Result of FASTA (omim) for
pFN21AE3021
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3021, 108 aa
1>>>pF1KE3021 108 - 108 aa - 108 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.7060+/-0.000252; mu= 13.5022+/- 0.016
mean_var=68.2081+/-13.103, 0's: 0 Z-trim(121.6): 24 B-trim: 33 in 1/57
Lambda= 0.155295
statistics sampled from 38309 (38340) to 38309 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.805), E-opt: 0.2 (0.45), width: 16
Scan time: 4.450
The best scores are: opt bits E(85289)
NP_068754 (OMIM: 607002,610628) prokineticin-2 iso ( 108) 792 185.0 2.1e-47
NP_001119600 (OMIM: 607002,610628) prokineticin-2 ( 129) 535 127.5 5.1e-30
NP_115790 (OMIM: 606233) prokineticin-1 precursor ( 105) 408 98.9 1.6e-21
XP_016862463 (OMIM: 607002,610628) PREDICTED: prok ( 109) 332 81.9 2.2e-16
NP_055236 (OMIM: 605415) dickkopf-related protein ( 259) 149 41.3 0.00091
NP_055235 (OMIM: 605417) dickkopf-related protein ( 224) 148 41.0 0.00095
XP_016868805 (OMIM: 605417) PREDICTED: dickkopf-re ( 224) 148 41.0 0.00095
XP_011542790 (OMIM: 605417) PREDICTED: dickkopf-re ( 224) 148 41.0 0.00095
NP_056965 (OMIM: 605416) dickkopf-related protein ( 350) 144 40.3 0.0025
NP_037385 (OMIM: 605416) dickkopf-related protein ( 350) 144 40.3 0.0025
NP_001018067 (OMIM: 605416) dickkopf-related prote ( 350) 144 40.3 0.0025
XP_006718241 (OMIM: 605416) PREDICTED: dickkopf-re ( 350) 144 40.3 0.0025
NP_001317149 (OMIM: 605416) dickkopf-related prote ( 364) 140 39.4 0.0047
XP_016873043 (OMIM: 605416) PREDICTED: dickkopf-re ( 364) 140 39.4 0.0047
XP_016873044 (OMIM: 605416) PREDICTED: dickkopf-re ( 364) 140 39.4 0.0047
>>NP_068754 (OMIM: 607002,610628) prokineticin-2 isoform (108 aa)
initn: 792 init1: 792 opt: 792 Z-score: 972.2 bits: 185.0 E(85289): 2.1e-47
Smith-Waterman score: 792; 100.0% identity (100.0% similar) in 108 aa overlap (1-108:1-108)
10 20 30 40 50 60
pF1KE3 MRSLCCAPLLLLLLLPPLLLTPRAGDAAVITGACDKDSQCGGGMCCAVSIWVKSIRICTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 MRSLCCAPLLLLLLLPPLLLTPRAGDAAVITGACDKDSQCGGGMCCAVSIWVKSIRICTP
10 20 30 40 50 60
70 80 90 100
pF1KE3 MGKLGDSCHPLTRKVPFFGRRMHHTCPCLPGLACLRTSFNRFICLAQK
::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 MGKLGDSCHPLTRKVPFFGRRMHHTCPCLPGLACLRTSFNRFICLAQK
70 80 90 100
>>NP_001119600 (OMIM: 607002,610628) prokineticin-2 isof (129 aa)
initn: 532 init1: 532 opt: 535 Z-score: 660.0 bits: 127.5 E(85289): 5.1e-30
Smith-Waterman score: 740; 83.7% identity (83.7% similar) in 129 aa overlap (1-108:1-129)
10 20 30 40 50 60
pF1KE3 MRSLCCAPLLLLLLLPPLLLTPRAGDAAVITGACDKDSQCGGGMCCAVSIWVKSIRICTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRSLCCAPLLLLLLLPPLLLTPRAGDAAVITGACDKDSQCGGGMCCAVSIWVKSIRICTP
10 20 30 40 50 60
70 80 90
pF1KE3 MGKLGDSCHPLTRK---------------------VPFFGRRMHHTCPCLPGLACLRTSF
:::::::::::::: :::::::::::::::::::::::::
NP_001 MGKLGDSCHPLTRKNNFGNGRQERRKRKRSKRKKEVPFFGRRMHHTCPCLPGLACLRTSF
70 80 90 100 110 120
100
pF1KE3 NRFICLAQK
:::::::::
NP_001 NRFICLAQK
>>NP_115790 (OMIM: 606233) prokineticin-1 precursor [Hom (105 aa)
initn: 429 init1: 393 opt: 408 Z-score: 507.4 bits: 98.9 E(85289): 1.6e-21
Smith-Waterman score: 408; 55.2% identity (80.5% similar) in 87 aa overlap (18-104:10-96)
10 20 30 40 50 60
pF1KE3 MRSLCCAPLLLLLLLPPLLLTPRAGDAAVITGACDKDSQCGGGMCCAVSIWVKSIRICTP
.:: ..: :::::::..: :::.: :::.:.:....:.:::
NP_115 MRGATRVSIMLLLVTVSDCAVITGACERDVQCGAGTCCAISLWLRGLRMCTP
10 20 30 40 50
70 80 90 100
pF1KE3 MGKLGDSCHPLTRKVPFFGRRMHHTCPCLPGLACLRTSFNRFICLAQK
.:. :. ::: ..::::: .: ::::::::.: : : .:. :
NP_115 LGREGEECHPGSHKVPFFRKRKHHTCPCLPNLLCSRFPDGRYRCSMDLKNINF
60 70 80 90 100
>>XP_016862463 (OMIM: 607002,610628) PREDICTED: prokinet (109 aa)
initn: 329 init1: 329 opt: 332 Z-score: 415.1 bits: 81.9 E(85289): 2.2e-16
Smith-Waterman score: 537; 75.0% identity (76.9% similar) in 104 aa overlap (26-108:6-109)
10 20 30 40 50 60
pF1KE3 MRSLCCAPLLLLLLLPPLLLTPRAGDAAVITGACDKDSQCGGGMCCAVSIWVKSIRICTP
: . : .::::::::::::::::::::::::::::
XP_016 MFKLRDDVFIFSACDKDSQCGGGMCCAVSIWVKSIRICTP
10 20 30 40
70 80 90
pF1KE3 MGKLGDSCHPLTRK---------------------VPFFGRRMHHTCPCLPGLACLRTSF
:::::::::::::: :::::::::::::::::::::::::
XP_016 MGKLGDSCHPLTRKNNFGNGRQERRKRKRSKRKKEVPFFGRRMHHTCPCLPGLACLRTSF
50 60 70 80 90 100
100
pF1KE3 NRFICLAQK
:::::::::
XP_016 NRFICLAQK
>>NP_055236 (OMIM: 605415) dickkopf-related protein 2 pr (259 aa)
initn: 98 init1: 48 opt: 149 Z-score: 188.6 bits: 41.3 E(85289): 0.00091
Smith-Waterman score: 149; 36.1% identity (57.4% similar) in 61 aa overlap (34-94:183-239)
10 20 30 40 50 60
pF1KE3 LCCAPLLLLLLLPPLLLTPRAGDAAVITGACDKDSQCGGGMCCAVSIWVKSIRICTPMGK
: ..:.: :.::: .:.: :: :. .
NP_055 GHYSNHDLGWQNLGRPHTKMSHIKGHEGDPCLRSSDCIEGFCCARHFWTK---ICKPVLH
160 170 180 190 200
70 80 90 100
pF1KE3 LGDSCHPLTRKVPFFGRRMHHTCPCLPGLACLRTSFNRFICLAQK
:. : :: : .. . : : ::.:
NP_055 QGEVCTK-QRKKGSHGLEIFQRCDCAKGLSCKVWKDATYSSKARLHVCQKI
210 220 230 240 250
>>NP_055235 (OMIM: 605417) dickkopf-related protein 4 pr (224 aa)
initn: 174 init1: 78 opt: 148 Z-score: 188.3 bits: 41.0 E(85289): 0.00095
Smith-Waterman score: 148; 36.4% identity (54.5% similar) in 66 aa overlap (33-94:144-202)
10 20 30 40 50 60
pF1KE3 SLCCAPLLLLLLLPPLLLTPRAGDAAVITGACDKDSQCGGGMCCAVSIWVKSIRICTPMG
.: . .:: :.::: .:.: :: :.
NP_055 GTTGHPVQENQPKRKPSIKKSQGRKGQEGESCLRTFDCGPGLCCARHFWTK---ICKPVL
120 130 140 150 160 170
70 80 90 100
pF1KE3 KLGDSC----HPLTRKVPFFGRRMHHTCPCLPGLACLRTSFNRFICLAQK
:. : : : ..: . .: : : ::: :
NP_055 LEGQVCSRRGHKDTAQAPEIFQR----CDCGPGLLCRSQLTSNRQHARLRVCQKIEKL
180 190 200 210 220
>>XP_016868805 (OMIM: 605417) PREDICTED: dickkopf-relate (224 aa)
initn: 174 init1: 78 opt: 148 Z-score: 188.3 bits: 41.0 E(85289): 0.00095
Smith-Waterman score: 148; 36.4% identity (54.5% similar) in 66 aa overlap (33-94:144-202)
10 20 30 40 50 60
pF1KE3 SLCCAPLLLLLLLPPLLLTPRAGDAAVITGACDKDSQCGGGMCCAVSIWVKSIRICTPMG
.: . .:: :.::: .:.: :: :.
XP_016 GTTGHPVQENQPKRKPSIKKSQGRKGQEGESCLRTFDCGPGLCCARHFWTK---ICKPVL
120 130 140 150 160 170
70 80 90 100
pF1KE3 KLGDSC----HPLTRKVPFFGRRMHHTCPCLPGLACLRTSFNRFICLAQK
:. : : : ..: . .: : : ::: :
XP_016 LEGQVCSRRGHKDTAQAPEIFQR----CDCGPGLLCRSQLTSNRQHARLRVCQKIEKL
180 190 200 210 220
>>XP_011542790 (OMIM: 605417) PREDICTED: dickkopf-relate (224 aa)
initn: 174 init1: 78 opt: 148 Z-score: 188.3 bits: 41.0 E(85289): 0.00095
Smith-Waterman score: 148; 36.4% identity (54.5% similar) in 66 aa overlap (33-94:144-202)
10 20 30 40 50 60
pF1KE3 SLCCAPLLLLLLLPPLLLTPRAGDAAVITGACDKDSQCGGGMCCAVSIWVKSIRICTPMG
.: . .:: :.::: .:.: :: :.
XP_011 GTTGHPVQENQPKRKPSIKKSQGRKGQEGESCLRTFDCGPGLCCARHFWTK---ICKPVL
120 130 140 150 160 170
70 80 90 100
pF1KE3 KLGDSC----HPLTRKVPFFGRRMHHTCPCLPGLACLRTSFNRFICLAQK
:. : : : ..: . .: : : ::: :
XP_011 LEGQVCSRRGHKDTAQAPEIFQR----CDCGPGLLCRSQLTSNRQHARLRVCQKIEKL
180 190 200 210 220
>>NP_056965 (OMIM: 605416) dickkopf-related protein 3 is (350 aa)
initn: 171 init1: 71 opt: 144 Z-score: 180.9 bits: 40.3 E(85289): 0.0025
Smith-Waterman score: 144; 26.6% identity (53.2% similar) in 109 aa overlap (3-104:182-284)
10 20 30
pF1KE3 MRSLCCAPLLLLLLLPPLLLTPRAGDAAVITG
: ::. : . . : :......
NP_056 DCGPSMYCQFASFQYTCQPCRGQRMLCTRDSECCGDQLCVWGHCTKMAT-RGSNGTI---
160 170 180 190 200
40 50 60 70 80
pF1KE3 ACDKDSQCGGGMCCAVSIWVKSIRICTPMGKLGDSCH-PLTRKVPFFGRRMH-----HTC
::.. .: :.::: . . . .:::. :. :: : .: . .. ... :
NP_056 -CDNQRDCQPGLCCAFQRGLL-FPVCTPLPVEGELCHDPASRLLDLITWELEPDGALDRC
210 220 230 240 250 260
90 100
pF1KE3 PCLPGLACLRTSFNR-FICLAQK
:: :: : : . ..:
NP_056 PCASGLLCQPHSHSLVYVCKPTFVGSRDQDGEILLPREVPDEYEVGSFMEEVRQELEDLE
270 280 290 300 310 320
>>NP_037385 (OMIM: 605416) dickkopf-related protein 3 is (350 aa)
initn: 171 init1: 71 opt: 144 Z-score: 180.9 bits: 40.3 E(85289): 0.0025
Smith-Waterman score: 144; 26.6% identity (53.2% similar) in 109 aa overlap (3-104:182-284)
10 20 30
pF1KE3 MRSLCCAPLLLLLLLPPLLLTPRAGDAAVITG
: ::. : . . : :......
NP_037 DCGPSMYCQFASFQYTCQPCRGQRMLCTRDSECCGDQLCVWGHCTKMAT-RGSNGTI---
160 170 180 190 200
40 50 60 70 80
pF1KE3 ACDKDSQCGGGMCCAVSIWVKSIRICTPMGKLGDSCH-PLTRKVPFFGRRMH-----HTC
::.. .: :.::: . . . .:::. :. :: : .: . .. ... :
NP_037 -CDNQRDCQPGLCCAFQRGLL-FPVCTPLPVEGELCHDPASRLLDLITWELEPDGALDRC
210 220 230 240 250 260
90 100
pF1KE3 PCLPGLACLRTSFNR-FICLAQK
:: :: : : . ..:
NP_037 PCASGLLCQPHSHSLVYVCKPTFVGSRDQDGEILLPREVPDEYEVGSFMEEVRQELEDLE
270 280 290 300 310 320
108 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 17:44:47 2016 done: Sun Nov 6 17:44:48 2016
Total Scan time: 4.450 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]