Result of FASTA (omim) for
pFN21AE2745
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2745, 387 aa
1>>>pF1KE2745 387 - 387 aa - 387 aa
Library: /omim/omim.rfq.tfa
65951994 residues in 93482 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.9531+/-0.000304; mu= 9.1772+/- 0.019
mean_var=105.0769+/-20.659, 0's: 0 Z-trim(118.9): 35 B-trim: 0 in 0/56
Lambda= 0.125118
statistics sampled from 33784 (33819) to 33784 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.722), E-opt: 0.2 (0.362), width: 16
Scan time: 4.580
The best scores are: opt bits E(93482)
XP_006713552 (OMIM: 600570,605635,607628,615651) c ( 863) 2517 464.8 3.6e-130
NP_001164560 (OMIM: 600570,605635,607628,615651) c ( 869) 2305 426.6 1.2e-118
XP_006713553 (OMIM: 600570,605635,607628,615651) c ( 512) 1908 354.8 2.9e-97
XP_011510703 (OMIM: 600570,605635,607628,615651) c ( 835) 1908 354.9 4.4e-97
NP_001164559 (OMIM: 600570,605635,607628,615651) c ( 854) 1908 354.9 4.5e-97
NP_004357 (OMIM: 600570,605635,607628,615651) chlo ( 898) 1908 354.9 4.7e-97
NP_001164558 (OMIM: 600570,605635,607628,615651) c ( 881) 1861 346.4 1.6e-94
XP_011514084 (OMIM: 118425,160800,255700) chloride ( 570) 750 145.8 2.6e-34
XP_016867229 (OMIM: 118425,160800,255700) chloride ( 838) 750 145.9 3.7e-34
XP_016867228 (OMIM: 118425,160800,255700) chloride ( 846) 750 145.9 3.7e-34
NP_000074 (OMIM: 118425,160800,255700) chloride ch ( 988) 750 145.9 4.3e-34
NP_001244068 (OMIM: 602024,613090) chloride channe ( 644) 489 98.7 4.5e-20
NP_001036169 (OMIM: 602024,613090) chloride channe ( 686) 489 98.7 4.7e-20
NP_004061 (OMIM: 602024,613090) chloride channel p ( 687) 489 98.7 4.7e-20
NP_001159417 (OMIM: 602023,607364,613090) chloride ( 517) 484 97.8 6.9e-20
NP_000076 (OMIM: 602023,607364,613090) chloride ch ( 687) 482 97.5 1.1e-19
NP_000075 (OMIM: 300008,300009,300554,308990,31046 ( 746) 221 50.4 1.9e-05
NP_001269092 (OMIM: 300008,300009,300554,308990,31 ( 766) 221 50.4 1.9e-05
NP_001121371 (OMIM: 300008,300009,300554,308990,31 ( 816) 221 50.4 2e-05
NP_001121370 (OMIM: 300008,300009,300554,308990,31 ( 816) 221 50.4 2e-05
XP_016884746 (OMIM: 300008,300009,300554,308990,31 ( 820) 221 50.4 2e-05
XP_016884747 (OMIM: 300008,300009,300554,308990,31 ( 820) 221 50.4 2e-05
NP_001230301 (OMIM: 600580) H(+)/Cl(-) exchange tr ( 791) 213 48.9 5.3e-05
NP_001230303 (OMIM: 600580) H(+)/Cl(-) exchange tr ( 791) 213 48.9 5.3e-05
NP_001820 (OMIM: 600580) H(+)/Cl(-) exchange trans ( 818) 213 48.9 5.5e-05
XP_011529888 (OMIM: 600580) H(+)/Cl(-) exchange tr ( 831) 213 48.9 5.5e-05
XP_005262783 (OMIM: 600580) H(+)/Cl(-) exchange tr ( 839) 213 49.0 5.6e-05
NP_776297 (OMIM: 600580) H(+)/Cl(-) exchange trans ( 866) 213 49.0 5.7e-05
NP_001243873 (OMIM: 300114,302910) H(+)/Cl(-) exch ( 666) 209 48.2 7.5e-05
NP_001821 (OMIM: 300114,302910) H(+)/Cl(-) exchang ( 760) 209 48.2 8.4e-05
XP_011520656 (OMIM: 166600,602727,611490) H(+)/Cl( ( 747) 196 45.9 0.00042
NP_001107803 (OMIM: 166600,602727,611490) H(+)/Cl( ( 781) 196 45.9 0.00044
NP_001278 (OMIM: 166600,602727,611490) H(+)/Cl(-) ( 805) 196 45.9 0.00045
NP_001243888 (OMIM: 602726) chloride transport pro ( 847) 174 41.9 0.0074
NP_001277 (OMIM: 602726) chloride transport protei ( 869) 174 41.9 0.0076
>>XP_006713552 (OMIM: 600570,605635,607628,615651) chlor (863 aa)
initn: 2517 init1: 2517 opt: 2517 Z-score: 2458.6 bits: 464.8 E(93482): 3.6e-130
Smith-Waterman score: 2517; 99.7% identity (100.0% similar) in 387 aa overlap (1-387:477-863)
10 20 30
pF1KE2 MAAWFPDGIHTDSSTYRIVPGGYAVVGAAA
::::::::::::::::::::::::::::::
XP_006 ALATTIPVPCGAFMPVFVIGAAFGRLVGESMAAWFPDGIHTDSSTYRIVPGGYAVVGAAA
450 460 470 480 490 500
40 50 60 70 80 90
pF1KE2 LAGAVTHTVSTAVIVFELTGQIAHILPVMIVVILANAVAQSLQPSLYDSIIRIKKLPYLP
::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::
XP_006 LAGAVTHTVSTAVIVFELTGQIAHILPVMIAVILANAVAQSLQPSLYDSIIRIKKLPYLP
510 520 530 540 550 560
100 110 120 130 140 150
pF1KE2 ELGWGRHQQYRVRVEDIMVRDVPHVALSCTFRDLRLALHRTKGRMLALVESPESMILLGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELGWGRHQQYRVRVEDIMVRDVPHVALSCTFRDLRLALHRTKGRMLALVESPESMILLGS
570 580 590 600 610 620
160 170 180 190 200 210
pF1KE2 IERSQVVALLGAQLSPARRRQHMQERRATQTSPLSDQEGPPTPEASVCFQVNTEDSAFPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IERSQVVALLGAQLSPARRRQHMQERRATQTSPLSDQEGPPTPEASVCFQVNTEDSAFPA
630 640 650 660 670 680
220 230 240 250 260 270
pF1KE2 ARGETHKPLKPALKRGPSVTRNLGESPTGSAESAGIALRSLFCGSPPPEAASEKLESCEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ARGETHKPLKPALKRGPSVTRNLGESPTGSAESAGIALRSLFCGSPPPEAASEKLESCEK
690 700 710 720 730 740
280 290 300 310 320 330
pF1KE2 RKLKRVRISLASDADLEGEMSPEETHTIFSLLGVDHAYVTSIGRLIGIVTLKELRKAIEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RKLKRVRISLASDADLEGEMSPEETHTIFSLLGVDHAYVTSIGRLIGIVTLKELRKAIEG
750 760 770 780 790 800
340 350 360 370 380
pF1KE2 SVTAQGVKVRPPLASFRDSATSSSDTETTEVHALWGPHSRHGLPREGSPSDSDDKCQ
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SVTAQGVKVRPPLASFRDSATSSSDTETTEVHALWGPHSRHGLPREGSPSDSDDKCQ
810 820 830 840 850 860
>>NP_001164560 (OMIM: 600570,605635,607628,615651) chlor (869 aa)
initn: 2334 init1: 1908 opt: 2305 Z-score: 2251.7 bits: 426.6 E(93482): 1.2e-118
Smith-Waterman score: 2314; 91.4% identity (93.5% similar) in 397 aa overlap (1-387:477-869)
10 20 30
pF1KE2 MAAWFPDGIHTDSSTYRIVPGGYAVVGAAA
::::::::::::::::::::::::::::::
NP_001 ALATTIPVPCGAFMPVFVIGAAFGRLVGESMAAWFPDGIHTDSSTYRIVPGGYAVVGAAA
450 460 470 480 490 500
40 50 60 70 80 90
pF1KE2 LAGAVTHTVSTAVIVFELTGQIAHILPVMIVVILANAVAQSLQPSLYDSIIRIKKLPYLP
::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::
NP_001 LAGAVTHTVSTAVIVFELTGQIAHILPVMIAVILANAVAQSLQPSLYDSIIRIKKLPYLP
510 520 530 540 550 560
100 110 120 130 140 150
pF1KE2 ELGWGRHQQYRVRVEDIMVRDVPHVALSCTFRDLRLALHRTKGRMLALVESPESMILLGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELGWGRHQQYRVRVEDIMVRDVPHVALSCTFRDLRLALHRTKGRMLALVESPESMILLGS
570 580 590 600 610 620
160 170 180 190 200 210
pF1KE2 IERSQVVALLGAQLSPARRRQHMQERRATQTSPLSDQEGPPTPEASVCFQVNTEDSAFPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IERSQVVALLGAQLSPARRRQHMQERRATQTSPLSDQEGPPTPEASVCFQVNTEDSAFPA
630 640 650 660 670 680
220 230 240 250 260 270
pF1KE2 ARGETHKPLKPALKRGPSVTRNLGESPTGSAESAGIALRSLFCGSPPPEAASEKLESCEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARGETHKPLKPALKRGPSVTRNLGESPTGSAESAGIALRSLFCGSPPPEAASEKLESCEK
690 700 710 720 730 740
280 290 300 310 320
pF1KE2 RKLKRVRISLASDADLEGEMSPEET----------HTIFSLLGVDHAYVTSIGRLIGIVT
:::::::::::::::::::::::: . :: .: : . : ..
NP_001 RKLKRVRISLASDADLEGEMSPEEILEWEEQQLDEPVNFSDCKIDPAPFQLVER----TS
750 760 770 780 790 800
330 340 350 360 370 380
pF1KE2 LKELRKAIEGSVTAQGVKVRPPLASFRDSATSSSDTETTEVHALWGPHSRHGLPREGSPS
:..:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHKLRKAIEGSVTAQGVKVRPPLASFRDSATSSSDTETTEVHALWGPHSRHGLPREGSPS
810 820 830 840 850 860
pF1KE2 DSDDKCQ
:::::::
NP_001 DSDDKCQ
>>XP_006713553 (OMIM: 600570,605635,607628,615651) chlor (512 aa)
initn: 1935 init1: 1908 opt: 1908 Z-score: 1868.0 bits: 354.8 E(93482): 2.9e-97
Smith-Waterman score: 2411; 91.4% identity (91.6% similar) in 419 aa overlap (1-384:91-509)
10 20 30
pF1KE2 MAAWFPDGIHTDSSTYRIVPGGYAVVGAAA
::::::::::::::::::::::::::::::
XP_006 ALATTIPVPCGAFMPVFVIGAAFGRLVGESMAAWFPDGIHTDSSTYRIVPGGYAVVGAAA
70 80 90 100 110 120
40 50 60 70 80 90
pF1KE2 LAGAVTHTVSTAVIVFELTGQIAHILPVMIVVILANAVAQSLQPSLYDSIIRIKKLPYLP
::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::
XP_006 LAGAVTHTVSTAVIVFELTGQIAHILPVMIAVILANAVAQSLQPSLYDSIIRIKKLPYLP
130 140 150 160 170 180
100 110 120 130 140 150
pF1KE2 ELGWGRHQQYRVRVEDIMVRDVPHVALSCTFRDLRLALHRTKGRMLALVESPESMILLGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELGWGRHQQYRVRVEDIMVRDVPHVALSCTFRDLRLALHRTKGRMLALVESPESMILLGS
190 200 210 220 230 240
160 170 180 190 200 210
pF1KE2 IERSQVVALLGAQLSPARRRQHMQERRATQTSPLSDQEGPPTPEASVCFQVNTEDSAFPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IERSQVVALLGAQLSPARRRQHMQERRATQTSPLSDQEGPPTPEASVCFQVNTEDSAFPA
250 260 270 280 290 300
220 230 240 250 260 270
pF1KE2 ARGETHKPLKPALKRGPSVTRNLGESPTGSAESAGIALRSLFCGSPPPEAASEKLESCEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ARGETHKPLKPALKRGPSVTRNLGESPTGSAESAGIALRSLFCGSPPPEAASEKLESCEK
310 320 330 340 350 360
280 290
pF1KE2 RKLKRVRISLASDADLEGEMSPEE-----------------------------------T
:::::::::::::::::::::::: :
XP_006 RKLKRVRISLASDADLEGEMSPEEILEWEEQQLDEPVNFSDCKIDPAPFQLVERTSLHKT
370 380 390 400 410 420
300 310 320 330 340 350
pF1KE2 HTIFSLLGVDHAYVTSIGRLIGIVTLKELRKAIEGSVTAQGVKVRPPLASFRDSATSSSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HTIFSLLGVDHAYVTSIGRLIGIVTLKELRKAIEGSVTAQGVKVRPPLASFRDSATSSSD
430 440 450 460 470 480
360 370 380
pF1KE2 TETTEVHALWGPHSRHGLPREGSPSDSDDKCQ
:::::::::::::::::::::::::::::
XP_006 TETTEVHALWGPHSRHGLPREGSPSDSDDKCQ
490 500 510
>>XP_011510703 (OMIM: 600570,605635,607628,615651) chlor (835 aa)
initn: 1908 init1: 1908 opt: 1908 Z-score: 1864.7 bits: 354.9 E(93482): 4.4e-97
Smith-Waterman score: 1908; 99.7% identity (100.0% similar) in 294 aa overlap (1-294:477-770)
10 20 30
pF1KE2 MAAWFPDGIHTDSSTYRIVPGGYAVVGAAA
::::::::::::::::::::::::::::::
XP_011 ALATTIPVPCGAFMPVFVIGAAFGRLVGESMAAWFPDGIHTDSSTYRIVPGGYAVVGAAA
450 460 470 480 490 500
40 50 60 70 80 90
pF1KE2 LAGAVTHTVSTAVIVFELTGQIAHILPVMIVVILANAVAQSLQPSLYDSIIRIKKLPYLP
::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::
XP_011 LAGAVTHTVSTAVIVFELTGQIAHILPVMIAVILANAVAQSLQPSLYDSIIRIKKLPYLP
510 520 530 540 550 560
100 110 120 130 140 150
pF1KE2 ELGWGRHQQYRVRVEDIMVRDVPHVALSCTFRDLRLALHRTKGRMLALVESPESMILLGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELGWGRHQQYRVRVEDIMVRDVPHVALSCTFRDLRLALHRTKGRMLALVESPESMILLGS
570 580 590 600 610 620
160 170 180 190 200 210
pF1KE2 IERSQVVALLGAQLSPARRRQHMQERRATQTSPLSDQEGPPTPEASVCFQVNTEDSAFPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IERSQVVALLGAQLSPARRRQHMQERRATQTSPLSDQEGPPTPEASVCFQVNTEDSAFPA
630 640 650 660 670 680
220 230 240 250 260 270
pF1KE2 ARGETHKPLKPALKRGPSVTRNLGESPTGSAESAGIALRSLFCGSPPPEAASEKLESCEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARGETHKPLKPALKRGPSVTRNLGESPTGSAESAGIALRSLFCGSPPPEAASEKLESCEK
690 700 710 720 730 740
280 290 300 310 320 330
pF1KE2 RKLKRVRISLASDADLEGEMSPEETHTIFSLLGVDHAYVTSIGRLIGIVTLKELRKAIEG
::::::::::::::::::::::::
XP_011 RKLKRVRISLASDADLEGEMSPEEILEWEEQQLDEPVNFSDCKIDPAPFQLVERTSLHKP
750 760 770 780 790 800
>>NP_001164559 (OMIM: 600570,605635,607628,615651) chlor (854 aa)
initn: 1935 init1: 1908 opt: 1908 Z-score: 1864.5 bits: 354.9 E(93482): 4.5e-97
Smith-Waterman score: 2411; 91.4% identity (91.6% similar) in 419 aa overlap (1-384:433-851)
10 20 30
pF1KE2 MAAWFPDGIHTDSSTYRIVPGGYAVVGAAA
::::::::::::::::::::::::::::::
NP_001 ALATTIPVPCGAFMPVFVIGAAFGRLVGESMAAWFPDGIHTDSSTYRIVPGGYAVVGAAA
410 420 430 440 450 460
40 50 60 70 80 90
pF1KE2 LAGAVTHTVSTAVIVFELTGQIAHILPVMIVVILANAVAQSLQPSLYDSIIRIKKLPYLP
::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::
NP_001 LAGAVTHTVSTAVIVFELTGQIAHILPVMIAVILANAVAQSLQPSLYDSIIRIKKLPYLP
470 480 490 500 510 520
100 110 120 130 140 150
pF1KE2 ELGWGRHQQYRVRVEDIMVRDVPHVALSCTFRDLRLALHRTKGRMLALVESPESMILLGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELGWGRHQQYRVRVEDIMVRDVPHVALSCTFRDLRLALHRTKGRMLALVESPESMILLGS
530 540 550 560 570 580
160 170 180 190 200 210
pF1KE2 IERSQVVALLGAQLSPARRRQHMQERRATQTSPLSDQEGPPTPEASVCFQVNTEDSAFPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IERSQVVALLGAQLSPARRRQHMQERRATQTSPLSDQEGPPTPEASVCFQVNTEDSAFPA
590 600 610 620 630 640
220 230 240 250 260 270
pF1KE2 ARGETHKPLKPALKRGPSVTRNLGESPTGSAESAGIALRSLFCGSPPPEAASEKLESCEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARGETHKPLKPALKRGPSVTRNLGESPTGSAESAGIALRSLFCGSPPPEAASEKLESCEK
650 660 670 680 690 700
280 290
pF1KE2 RKLKRVRISLASDADLEGEMSPEE-----------------------------------T
:::::::::::::::::::::::: :
NP_001 RKLKRVRISLASDADLEGEMSPEEILEWEEQQLDEPVNFSDCKIDPAPFQLVERTSLHKT
710 720 730 740 750 760
300 310 320 330 340 350
pF1KE2 HTIFSLLGVDHAYVTSIGRLIGIVTLKELRKAIEGSVTAQGVKVRPPLASFRDSATSSSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HTIFSLLGVDHAYVTSIGRLIGIVTLKELRKAIEGSVTAQGVKVRPPLASFRDSATSSSD
770 780 790 800 810 820
360 370 380
pF1KE2 TETTEVHALWGPHSRHGLPREGSPSDSDDKCQ
:::::::::::::::::::::::::::::
NP_001 TETTEVHALWGPHSRHGLPREGSPSDSDDKCQ
830 840 850
>>NP_004357 (OMIM: 600570,605635,607628,615651) chloride (898 aa)
initn: 1935 init1: 1908 opt: 1908 Z-score: 1864.2 bits: 354.9 E(93482): 4.7e-97
Smith-Waterman score: 2411; 91.4% identity (91.6% similar) in 419 aa overlap (1-384:477-895)
10 20 30
pF1KE2 MAAWFPDGIHTDSSTYRIVPGGYAVVGAAA
::::::::::::::::::::::::::::::
NP_004 ALATTIPVPCGAFMPVFVIGAAFGRLVGESMAAWFPDGIHTDSSTYRIVPGGYAVVGAAA
450 460 470 480 490 500
40 50 60 70 80 90
pF1KE2 LAGAVTHTVSTAVIVFELTGQIAHILPVMIVVILANAVAQSLQPSLYDSIIRIKKLPYLP
::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::
NP_004 LAGAVTHTVSTAVIVFELTGQIAHILPVMIAVILANAVAQSLQPSLYDSIIRIKKLPYLP
510 520 530 540 550 560
100 110 120 130 140 150
pF1KE2 ELGWGRHQQYRVRVEDIMVRDVPHVALSCTFRDLRLALHRTKGRMLALVESPESMILLGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ELGWGRHQQYRVRVEDIMVRDVPHVALSCTFRDLRLALHRTKGRMLALVESPESMILLGS
570 580 590 600 610 620
160 170 180 190 200 210
pF1KE2 IERSQVVALLGAQLSPARRRQHMQERRATQTSPLSDQEGPPTPEASVCFQVNTEDSAFPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 IERSQVVALLGAQLSPARRRQHMQERRATQTSPLSDQEGPPTPEASVCFQVNTEDSAFPA
630 640 650 660 670 680
220 230 240 250 260 270
pF1KE2 ARGETHKPLKPALKRGPSVTRNLGESPTGSAESAGIALRSLFCGSPPPEAASEKLESCEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ARGETHKPLKPALKRGPSVTRNLGESPTGSAESAGIALRSLFCGSPPPEAASEKLESCEK
690 700 710 720 730 740
280 290
pF1KE2 RKLKRVRISLASDADLEGEMSPEE-----------------------------------T
:::::::::::::::::::::::: :
NP_004 RKLKRVRISLASDADLEGEMSPEEILEWEEQQLDEPVNFSDCKIDPAPFQLVERTSLHKT
750 760 770 780 790 800
300 310 320 330 340 350
pF1KE2 HTIFSLLGVDHAYVTSIGRLIGIVTLKELRKAIEGSVTAQGVKVRPPLASFRDSATSSSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 HTIFSLLGVDHAYVTSIGRLIGIVTLKELRKAIEGSVTAQGVKVRPPLASFRDSATSSSD
810 820 830 840 850 860
360 370 380
pF1KE2 TETTEVHALWGPHSRHGLPREGSPSDSDDKCQ
:::::::::::::::::::::::::::::
NP_004 TETTEVHALWGPHSRHGLPREGSPSDSDDKCQ
870 880 890
>>NP_001164558 (OMIM: 600570,605635,607628,615651) chlor (881 aa)
initn: 1888 init1: 1861 opt: 1861 Z-score: 1818.5 bits: 346.4 E(93482): 1.6e-94
Smith-Waterman score: 2364; 90.2% identity (90.9% similar) in 419 aa overlap (1-384:460-878)
10 20 30
pF1KE2 MAAWFPDGIHTDSSTYRIVPGGYAVVGAAA
: .. ::::::::::::::::::::::::
NP_001 NVFLTLVIFILMKFWMSALATTIPVPCGAFMPVFVIDGIHTDSSTYRIVPGGYAVVGAAA
430 440 450 460 470 480
40 50 60 70 80 90
pF1KE2 LAGAVTHTVSTAVIVFELTGQIAHILPVMIVVILANAVAQSLQPSLYDSIIRIKKLPYLP
::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::
NP_001 LAGAVTHTVSTAVIVFELTGQIAHILPVMIAVILANAVAQSLQPSLYDSIIRIKKLPYLP
490 500 510 520 530 540
100 110 120 130 140 150
pF1KE2 ELGWGRHQQYRVRVEDIMVRDVPHVALSCTFRDLRLALHRTKGRMLALVESPESMILLGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELGWGRHQQYRVRVEDIMVRDVPHVALSCTFRDLRLALHRTKGRMLALVESPESMILLGS
550 560 570 580 590 600
160 170 180 190 200 210
pF1KE2 IERSQVVALLGAQLSPARRRQHMQERRATQTSPLSDQEGPPTPEASVCFQVNTEDSAFPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IERSQVVALLGAQLSPARRRQHMQERRATQTSPLSDQEGPPTPEASVCFQVNTEDSAFPA
610 620 630 640 650 660
220 230 240 250 260 270
pF1KE2 ARGETHKPLKPALKRGPSVTRNLGESPTGSAESAGIALRSLFCGSPPPEAASEKLESCEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARGETHKPLKPALKRGPSVTRNLGESPTGSAESAGIALRSLFCGSPPPEAASEKLESCEK
670 680 690 700 710 720
280 290
pF1KE2 RKLKRVRISLASDADLEGEMSPEE-----------------------------------T
:::::::::::::::::::::::: :
NP_001 RKLKRVRISLASDADLEGEMSPEEILEWEEQQLDEPVNFSDCKIDPAPFQLVERTSLHKT
730 740 750 760 770 780
300 310 320 330 340 350
pF1KE2 HTIFSLLGVDHAYVTSIGRLIGIVTLKELRKAIEGSVTAQGVKVRPPLASFRDSATSSSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HTIFSLLGVDHAYVTSIGRLIGIVTLKELRKAIEGSVTAQGVKVRPPLASFRDSATSSSD
790 800 810 820 830 840
360 370 380
pF1KE2 TETTEVHALWGPHSRHGLPREGSPSDSDDKCQ
:::::::::::::::::::::::::::::
NP_001 TETTEVHALWGPHSRHGLPREGSPSDSDDKCQ
850 860 870 880
>>XP_011514084 (OMIM: 118425,160800,255700) chloride cha (570 aa)
initn: 925 init1: 714 opt: 750 Z-score: 737.6 bits: 145.8 E(93482): 2.6e-34
Smith-Waterman score: 933; 44.8% identity (64.0% similar) in 420 aa overlap (1-377:84-502)
10 20 30
pF1KE2 MAAWFPDGIHTDSSTYRIVPGGYAVVGAAA
:: ::::: :. :.:.::::::.::::
XP_011 IVATTMPIPCGGFMPVFVLGAAFGRLVGEIMAMLFPDGILFDDIIYKILPGGYAVIGAAA
60 70 80 90 100 110
40 50 60 70 80 90
pF1KE2 LAGAVTHTVSTAVIVFELTGQIAHILPVMIVVILANAVAQSLQPSLYDSIIRIKKLPYLP
:.:::.:::::::: ::::::::::::.:..::::: ::::::::::::::..:::::::
XP_011 LTGAVSHTVSTAVICFELTGQIAHILPMMVAVILANMVAQSLQPSLYDSIIQVKKLPYLP
120 130 140 150 160 170
100 110 120 130 140 150
pF1KE2 ELGWGRHQQYRVRVEDIMVRDVPHVALSCTFRDLRLALHRTKGRMLALVESPESMILLGS
.:::.. ..: . ::::::::: :. : :. .:: :. : . : ::.: .:::::::
XP_011 DLGWNQLSKYTIFVEDIMVRDVKFVSASYTYGELRTLLQTTTVKTLPLVDSKDSMILLGS
180 190 200 210 220 230
160 170 180 190 200
pF1KE2 IERSQVVALLGAQLSPARRRQHMQER-RATQTSPLSDQ-----EG----PPTPEASVCFQ
.:::.. ::: .: : :: . :: : . : . . :: :: : :
XP_011 VERSELQALLQRHLCPERRLRAAQEMARKLSELPYDGKARLAGEGLPGAPPGRPESFAFV
240 250 260 270 280 290
210 220 230 240 250
pF1KE2 VNTED------SAFP---AARGETHKPLKPALKRGP-SVTRNLGESPTGSAESAGIALRS
. :: : .: : . : ::.: :: .. :.: ... .:
XP_011 DEDEDEDLSGKSELPPSLALHPSTTAPLSPEEPNGPLPGHKQQPEAPEPAGQRPSIFQSL
300 310 320 330 340 350
260 270 280
pF1KE2 LFC--GSPPP--------------EAASEKLESCEKRKLKRVRISLASDAD-----LEGE
: : : : . . :..:. :...:.. . : : .
XP_011 LHCLLGRARPTKKKTTQDSTDLVDNMSPEEIEAWEQEQLSQPVCFDSCCIDQSPFQLVEQ
360 370 380 390 400 410
290 300 310 320 330 340
pF1KE2 MSPEETHTIFSLLGVDHAYVTSIGRLIGIVTLKELRKAIEGSVTAQGVKVRPPLASFRDS
. ..:::.:::::. :::::.:.: :...:.::.::::: : .::..::::::::..
XP_011 TTLHKTHTLFSLLGLHLAYVTSMGKLRGVLALEELQKAIEGH-TKSGVQLRPPLASFRNT
420 430 440 450 460 470
350 360 370 380
pF1KE2 ATSSSDTETTEVHAL-WG-PHSRHGLPREGSPSDSDDKCQ
... ..: . : :. :..: : :
XP_011 TSTRKSTGAPPSSAENWNLPEDRPGATGTGDVIAASPETPVPSPSPEPPLSLAPGKVEGE
480 490 500 510 520 530
>>XP_016867229 (OMIM: 118425,160800,255700) chloride cha (838 aa)
initn: 925 init1: 714 opt: 750 Z-score: 735.0 bits: 145.9 E(93482): 3.7e-34
Smith-Waterman score: 933; 44.8% identity (64.0% similar) in 420 aa overlap (1-377:352-770)
10 20 30
pF1KE2 MAAWFPDGIHTDSSTYRIVPGGYAVVGAAA
:: ::::: :. :.:.::::::.::::
XP_016 IVATTMPIPCGGFMPVFVLGAAFGRLVGEIMAMLFPDGILFDDIIYKILPGGYAVIGAAA
330 340 350 360 370 380
40 50 60 70 80 90
pF1KE2 LAGAVTHTVSTAVIVFELTGQIAHILPVMIVVILANAVAQSLQPSLYDSIIRIKKLPYLP
:.:::.:::::::: ::::::::::::.:..::::: ::::::::::::::..:::::::
XP_016 LTGAVSHTVSTAVICFELTGQIAHILPMMVAVILANMVAQSLQPSLYDSIIQVKKLPYLP
390 400 410 420 430 440
100 110 120 130 140 150
pF1KE2 ELGWGRHQQYRVRVEDIMVRDVPHVALSCTFRDLRLALHRTKGRMLALVESPESMILLGS
.:::.. ..: . ::::::::: :. : :. .:: :. : . : ::.: .:::::::
XP_016 DLGWNQLSKYTIFVEDIMVRDVKFVSASYTYGELRTLLQTTTVKTLPLVDSKDSMILLGS
450 460 470 480 490 500
160 170 180 190 200
pF1KE2 IERSQVVALLGAQLSPARRRQHMQER-RATQTSPLSDQ-----EG----PPTPEASVCFQ
.:::.. ::: .: : :: . :: : . : . . :: :: : :
XP_016 VERSELQALLQRHLCPERRLRAAQEMARKLSELPYDGKARLAGEGLPGAPPGRPESFAFV
510 520 530 540 550 560
210 220 230 240 250
pF1KE2 VNTED------SAFP---AARGETHKPLKPALKRGP-SVTRNLGESPTGSAESAGIALRS
. :: : .: : . : ::.: :: .. :.: ... .:
XP_016 DEDEDEDLSGKSELPPSLALHPSTTAPLSPEEPNGPLPGHKQQPEAPEPAGQRPSIFQSL
570 580 590 600 610 620
260 270 280
pF1KE2 LFC--GSPPP--------------EAASEKLESCEKRKLKRVRISLASDAD-----LEGE
: : : : . . :..:. :...:.. . : : .
XP_016 LHCLLGRARPTKKKTTQDSTDLVDNMSPEEIEAWEQEQLSQPVCFDSCCIDQSPFQLVEQ
630 640 650 660 670 680
290 300 310 320 330 340
pF1KE2 MSPEETHTIFSLLGVDHAYVTSIGRLIGIVTLKELRKAIEGSVTAQGVKVRPPLASFRDS
. ..:::.:::::. :::::.:.: :...:.::.::::: : .::..::::::::..
XP_016 TTLHKTHTLFSLLGLHLAYVTSMGKLRGVLALEELQKAIEGH-TKSGVQLRPPLASFRNT
690 700 710 720 730 740
350 360 370 380
pF1KE2 ATSSSDTETTEVHAL-WG-PHSRHGLPREGSPSDSDDKCQ
... ..: . : :. :..: : :
XP_016 TSTRKSTGAPPSSAENWNLPEDRPGATGTGDVIAASPETPVPSPSPEPPLSLAPGKVEGE
750 760 770 780 790 800
>>XP_016867228 (OMIM: 118425,160800,255700) chloride cha (846 aa)
initn: 925 init1: 714 opt: 750 Z-score: 734.9 bits: 145.9 E(93482): 3.7e-34
Smith-Waterman score: 933; 44.8% identity (64.0% similar) in 420 aa overlap (1-377:360-778)
10 20 30
pF1KE2 MAAWFPDGIHTDSSTYRIVPGGYAVVGAAA
:: ::::: :. :.:.::::::.::::
XP_016 IVATTMPIPCGGFMPVFVLGAAFGRLVGEIMAMLFPDGILFDDIIYKILPGGYAVIGAAA
330 340 350 360 370 380
40 50 60 70 80 90
pF1KE2 LAGAVTHTVSTAVIVFELTGQIAHILPVMIVVILANAVAQSLQPSLYDSIIRIKKLPYLP
:.:::.:::::::: ::::::::::::.:..::::: ::::::::::::::..:::::::
XP_016 LTGAVSHTVSTAVICFELTGQIAHILPMMVAVILANMVAQSLQPSLYDSIIQVKKLPYLP
390 400 410 420 430 440
100 110 120 130 140 150
pF1KE2 ELGWGRHQQYRVRVEDIMVRDVPHVALSCTFRDLRLALHRTKGRMLALVESPESMILLGS
.:::.. ..: . ::::::::: :. : :. .:: :. : . : ::.: .:::::::
XP_016 DLGWNQLSKYTIFVEDIMVRDVKFVSASYTYGELRTLLQTTTVKTLPLVDSKDSMILLGS
450 460 470 480 490 500
160 170 180 190 200
pF1KE2 IERSQVVALLGAQLSPARRRQHMQER-RATQTSPLSDQ-----EG----PPTPEASVCFQ
.:::.. ::: .: : :: . :: : . : . . :: :: : :
XP_016 VERSELQALLQRHLCPERRLRAAQEMARKLSELPYDGKARLAGEGLPGAPPGRPESFAFV
510 520 530 540 550 560
210 220 230 240 250
pF1KE2 VNTED------SAFP---AARGETHKPLKPALKRGP-SVTRNLGESPTGSAESAGIALRS
. :: : .: : . : ::.: :: .. :.: ... .:
XP_016 DEDEDEDLSGKSELPPSLALHPSTTAPLSPEEPNGPLPGHKQQPEAPEPAGQRPSIFQSL
570 580 590 600 610 620
260 270 280
pF1KE2 LFC--GSPPP--------------EAASEKLESCEKRKLKRVRISLASDAD-----LEGE
: : : : . . :..:. :...:.. . : : .
XP_016 LHCLLGRARPTKKKTTQDSTDLVDNMSPEEIEAWEQEQLSQPVCFDSCCIDQSPFQLVEQ
630 640 650 660 670 680
290 300 310 320 330 340
pF1KE2 MSPEETHTIFSLLGVDHAYVTSIGRLIGIVTLKELRKAIEGSVTAQGVKVRPPLASFRDS
. ..:::.:::::. :::::.:.: :...:.::.::::: : .::..::::::::..
XP_016 TTLHKTHTLFSLLGLHLAYVTSMGKLRGVLALEELQKAIEGH-TKSGVQLRPPLASFRNT
690 700 710 720 730 740
350 360 370 380
pF1KE2 ATSSSDTETTEVHAL-WG-PHSRHGLPREGSPSDSDDKCQ
... ..: . : :. :..: : :
XP_016 TSTRKSTGAPPSSAENWNLPEDRPGATGTGDVIAASPETPVPSPSPEPPLSLAPGKVEGE
750 760 770 780 790 800
387 residues in 1 query sequences
65951994 residues in 93482 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Jun 19 14:29:35 2019 done: Wed Jun 19 14:29:36 2019
Total Scan time: 4.580 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]