Result of FASTA (omim) for
pFN21AE2726
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2726, 422 aa
1>>>pF1KE2726 422 - 422 aa - 422 aa
Library: /omim/omim.rfq.tfa
64704883 residues in 91410 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3503+/-0.000438; mu= 16.8959+/- 0.027
mean_var=68.6495+/-14.945, 0's: 0 Z-trim(108.6): 134 B-trim: 1001 in 1/53
Lambda= 0.154795
statistics sampled from 17125 (17275) to 17125 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.551), E-opt: 0.2 (0.189), width: 16
Scan time: 3.800
The best scores are: opt bits E(91410)
NP_001017424 (OMIM: 603219) potassium channel subf ( 422) 2727 618.7 9.3e-177
XP_016856737 (OMIM: 603219) potassium channel subf ( 422) 2727 618.7 9.3e-177
XP_016856738 (OMIM: 603219) potassium channel subf ( 412) 2647 600.8 2.2e-171
NP_055032 (OMIM: 603219) potassium channel subfami ( 411) 2645 600.4 3e-171
NP_001017425 (OMIM: 603219) potassium channel subf ( 426) 2644 600.1 3.6e-171
XP_011507824 (OMIM: 603219) potassium channel subf ( 370) 2396 544.7 1.5e-154
XP_011507825 (OMIM: 603219) potassium channel subf ( 370) 2396 544.7 1.5e-154
XP_011507826 (OMIM: 603219) potassium channel subf ( 370) 2396 544.7 1.5e-154
NP_066984 (OMIM: 605873) potassium channel subfami ( 538) 1583 363.3 9.2e-100
NP_612191 (OMIM: 605873) potassium channel subfami ( 543) 1583 363.3 9.3e-100
NP_612190 (OMIM: 605873) potassium channel subfami ( 543) 1583 363.3 9.3e-100
XP_024305396 (OMIM: 605873) potassium channel subf ( 484) 1537 353.0 1e-96
XP_011535142 (OMIM: 605873) potassium channel subf ( 410) 1291 298.0 3.1e-80
NP_201567 (OMIM: 605720) potassium channel subfami ( 393) 1036 241.0 4.2e-63
NP_001304019 (OMIM: 605720) potassium channel subf ( 393) 1036 241.0 4.2e-63
NP_001128578 (OMIM: 607369) potassium channel subf ( 294) 651 155.0 2.5e-37
NP_115491 (OMIM: 607369) potassium channel subfami ( 309) 651 155.0 2.6e-37
XP_016866835 (OMIM: 607369) potassium channel subf ( 262) 590 141.3 2.9e-33
NP_001128579 (OMIM: 607369) potassium channel subf ( 262) 590 141.3 2.9e-33
NP_001128577 (OMIM: 607369) potassium channel subf ( 322) 590 141.4 3.4e-33
NP_003731 (OMIM: 603493) potassium channel subfami ( 499) 553 133.2 1.5e-30
XP_005249513 (OMIM: 603493) potassium channel subf ( 496) 533 128.8 3.3e-29
NP_113648 (OMIM: 607370) potassium channel subfami ( 332) 514 124.4 4.5e-28
NP_002236 (OMIM: 601745) potassium channel subfami ( 336) 504 122.2 2.2e-27
NP_001350713 (OMIM: 607369) potassium channel subf ( 197) 484 117.6 3.1e-26
NP_004814 (OMIM: 603939) potassium channel subfami ( 313) 457 111.7 2.9e-24
NP_001128583 (OMIM: 607370) potassium channel subf ( 271) 452 110.5 5.6e-24
NP_203134 (OMIM: 603940) potassium channel subfami ( 252) 389 96.4 9.1e-20
NP_258416 (OMIM: 603940) potassium channel subfami ( 252) 389 96.4 9.1e-20
NP_203133 (OMIM: 603940) potassium channel subfami ( 307) 390 96.7 9.2e-20
NP_005705 (OMIM: 603940) potassium channel subfami ( 257) 389 96.4 9.3e-20
NP_002237 (OMIM: 603220,615344) potassium channel ( 394) 391 97.0 9.7e-20
NP_071753 (OMIM: 607368) potassium channel subfami ( 330) 384 95.4 2.5e-19
XP_011515404 (OMIM: 605874,612292) potassium chann ( 374) 373 93.0 1.5e-18
NP_001269463 (OMIM: 605874,612292) potassium chann ( 374) 373 93.0 1.5e-18
XP_011515403 (OMIM: 605874,612292) potassium chann ( 401) 364 91.0 6.4e-18
XP_011542486 (OMIM: 601745) potassium channel subf ( 268) 301 76.8 7.9e-14
NP_071338 (OMIM: 607366) potassium channel subfami ( 430) 254 66.4 1.7e-10
NP_071337 (OMIM: 607367) potassium channel subfami ( 408) 242 63.7 1e-09
XP_005264350 (OMIM: 603220,615344) potassium chann ( 284) 236 62.3 1.9e-09
XP_016869020 (OMIM: 605874,612292) potassium chann ( 264) 232 61.4 3.4e-09
XP_016869019 (OMIM: 605874,612292) potassium chann ( 264) 232 61.4 3.4e-09
NP_862823 (OMIM: 613655,613656) potassium channel ( 384) 227 60.4 1e-08
XP_011515405 (OMIM: 605874,612292) potassium chann ( 291) 223 59.4 1.5e-08
XP_011525829 (OMIM: 603939) potassium channel subf ( 176) 195 53.0 7.5e-07
XP_016882995 (OMIM: 603939) potassium channel subf ( 185) 195 53.0 7.8e-07
XP_024307556 (OMIM: 603939) potassium channel subf ( 179) 188 51.5 2.2e-06
XP_006715298 (OMIM: 603493) potassium channel subf ( 317) 169 47.4 6.8e-05
>>NP_001017424 (OMIM: 603219) potassium channel subfamil (422 aa)
initn: 2727 init1: 2727 opt: 2727 Z-score: 3294.9 bits: 618.7 E(91410): 9.3e-177
Smith-Waterman score: 2727; 100.0% identity (100.0% similar) in 422 aa overlap (1-422:1-422)
10 20 30 40 50 60
pF1KE2 MMNPRAKRDFYLAAPDLLDPKSAAQNSKPRLSFSTKPTVLASRVESDTTINVMKWKTVST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MMNPRAKRDFYLAAPDLLDPKSAAQNSKPRLSFSTKPTVLASRVESDTTINVMKWKTVST
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 IFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 INAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 INAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 FGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAII
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 FKHIEGWSALDAIYFVVITLTTIGFGDYVAGGSDIEYLDFYKPVVWFWILVGLAYFAAVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FKHIEGWSALDAIYFVVITLTTIGFGDYVAGGSDIEYLDFYKPVVWFWILVGLAYFAAVL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 SMIGDWLRVISKKTKEEVGEFRAHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSIKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SMIGDWLRVISKKTKEEVGEFRAHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSIKRK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 LSAELAGNHNQELTPCRRTLSVNHLTSERDVLPPLLKTESIYLNGLTPHCAGEEIAVIEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSAELAGNHNQELTPCRRTLSVNHLTSERDVLPPLLKTESIYLNGLTPHCAGEEIAVIEN
370 380 390 400 410 420
pF1KE2 IK
::
NP_001 IK
>>XP_016856737 (OMIM: 603219) potassium channel subfamil (422 aa)
initn: 2727 init1: 2727 opt: 2727 Z-score: 3294.9 bits: 618.7 E(91410): 9.3e-177
Smith-Waterman score: 2727; 100.0% identity (100.0% similar) in 422 aa overlap (1-422:1-422)
10 20 30 40 50 60
pF1KE2 MMNPRAKRDFYLAAPDLLDPKSAAQNSKPRLSFSTKPTVLASRVESDTTINVMKWKTVST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MMNPRAKRDFYLAAPDLLDPKSAAQNSKPRLSFSTKPTVLASRVESDTTINVMKWKTVST
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 IFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 INAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 FGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAII
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 FKHIEGWSALDAIYFVVITLTTIGFGDYVAGGSDIEYLDFYKPVVWFWILVGLAYFAAVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FKHIEGWSALDAIYFVVITLTTIGFGDYVAGGSDIEYLDFYKPVVWFWILVGLAYFAAVL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 SMIGDWLRVISKKTKEEVGEFRAHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSIKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SMIGDWLRVISKKTKEEVGEFRAHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSIKRK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 LSAELAGNHNQELTPCRRTLSVNHLTSERDVLPPLLKTESIYLNGLTPHCAGEEIAVIEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSAELAGNHNQELTPCRRTLSVNHLTSERDVLPPLLKTESIYLNGLTPHCAGEEIAVIEN
370 380 390 400 410 420
pF1KE2 IK
::
XP_016 IK
>>XP_016856738 (OMIM: 603219) potassium channel subfamil (412 aa)
initn: 2647 init1: 2647 opt: 2647 Z-score: 3198.5 bits: 600.8 E(91410): 2.2e-171
Smith-Waterman score: 2647; 100.0% identity (100.0% similar) in 411 aa overlap (12-422:2-412)
10 20 30 40 50 60
pF1KE2 MMNPRAKRDFYLAAPDLLDPKSAAQNSKPRLSFSTKPTVLASRVESDTTINVMKWKTVST
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLAAPDLLDPKSAAQNSKPRLSFSTKPTVLASRVESDTTINVMKWKTVST
10 20 30 40 50
70 80 90 100 110 120
pF1KE2 IFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAA
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE2 INAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPL
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE2 FGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAII
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE2 FKHIEGWSALDAIYFVVITLTTIGFGDYVAGGSDIEYLDFYKPVVWFWILVGLAYFAAVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FKHIEGWSALDAIYFVVITLTTIGFGDYVAGGSDIEYLDFYKPVVWFWILVGLAYFAAVL
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE2 SMIGDWLRVISKKTKEEVGEFRAHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSIKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SMIGDWLRVISKKTKEEVGEFRAHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSIKRK
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE2 LSAELAGNHNQELTPCRRTLSVNHLTSERDVLPPLLKTESIYLNGLTPHCAGEEIAVIEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSAELAGNHNQELTPCRRTLSVNHLTSERDVLPPLLKTESIYLNGLTPHCAGEEIAVIEN
360 370 380 390 400 410
pF1KE2 IK
::
XP_016 IK
>>NP_055032 (OMIM: 603219) potassium channel subfamily K (411 aa)
initn: 2645 init1: 2645 opt: 2645 Z-score: 3196.1 bits: 600.4 E(91410): 3e-171
Smith-Waterman score: 2645; 99.8% identity (100.0% similar) in 411 aa overlap (12-422:1-411)
10 20 30 40 50 60
pF1KE2 MMNPRAKRDFYLAAPDLLDPKSAAQNSKPRLSFSTKPTVLASRVESDTTINVMKWKTVST
.::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MAAPDLLDPKSAAQNSKPRLSFSTKPTVLASRVESDTTINVMKWKTVST
10 20 30 40
70 80 90 100 110 120
pF1KE2 IFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 IFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAA
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE2 INAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 INAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPL
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE2 FGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 FGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAII
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE2 FKHIEGWSALDAIYFVVITLTTIGFGDYVAGGSDIEYLDFYKPVVWFWILVGLAYFAAVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 FKHIEGWSALDAIYFVVITLTTIGFGDYVAGGSDIEYLDFYKPVVWFWILVGLAYFAAVL
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE2 SMIGDWLRVISKKTKEEVGEFRAHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSIKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SMIGDWLRVISKKTKEEVGEFRAHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSIKRK
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE2 LSAELAGNHNQELTPCRRTLSVNHLTSERDVLPPLLKTESIYLNGLTPHCAGEEIAVIEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LSAELAGNHNQELTPCRRTLSVNHLTSERDVLPPLLKTESIYLNGLTPHCAGEEIAVIEN
350 360 370 380 390 400
pF1KE2 IK
::
NP_055 IK
410
>>NP_001017425 (OMIM: 603219) potassium channel subfamil (426 aa)
initn: 2643 init1: 2643 opt: 2644 Z-score: 3194.6 bits: 600.1 E(91410): 3.6e-171
Smith-Waterman score: 2644; 97.4% identity (98.1% similar) in 426 aa overlap (2-422:1-426)
10 20 30 40 50
pF1KE2 MMNPRAKRDF--Y---LAAPDLLDPKSAAQNSKPRLSFSTKPTVLASRVESDTTINVMKW
: : :.:. : .:::::::::::::::::::::::::::::::::::::::::::
NP_001 MLPSASRERPGYRAGVAAPDLLDPKSAAQNSKPRLSFSTKPTVLASRVESDTTINVMKW
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 KTVSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KTVSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQ
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE2 QIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYAL
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE2 LGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVA
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE2 LPAIIFKHIEGWSALDAIYFVVITLTTIGFGDYVAGGSDIEYLDFYKPVVWFWILVGLAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPAIIFKHIEGWSALDAIYFVVITLTTIGFGDYVAGGSDIEYLDFYKPVVWFWILVGLAY
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE2 FAAVLSMIGDWLRVISKKTKEEVGEFRAHAAEWTANVTAEFKETRRRLSVEIYDKFQRAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FAAVLSMIGDWLRVISKKTKEEVGEFRAHAAEWTANVTAEFKETRRRLSVEIYDKFQRAT
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE2 SIKRKLSAELAGNHNQELTPCRRTLSVNHLTSERDVLPPLLKTESIYLNGLTPHCAGEEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SIKRKLSAELAGNHNQELTPCRRTLSVNHLTSERDVLPPLLKTESIYLNGLTPHCAGEEI
360 370 380 390 400 410
420
pF1KE2 AVIENIK
:::::::
NP_001 AVIENIK
420
>>XP_011507824 (OMIM: 603219) potassium channel subfamil (370 aa)
initn: 2396 init1: 2396 opt: 2396 Z-score: 2896.2 bits: 544.7 E(91410): 1.5e-154
Smith-Waterman score: 2396; 100.0% identity (100.0% similar) in 370 aa overlap (53-422:1-370)
30 40 50 60 70 80
pF1KE2 AAQNSKPRLSFSTKPTVLASRVESDTTINVMKWKTVSTIFLVVVLYLIIGATVFKALEQP
::::::::::::::::::::::::::::::
XP_011 MKWKTVSTIFLVVVLYLIIGATVFKALEQP
10 20 30
90 100 110 120 130 140
pF1KE2 HEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAAINAGIIPLGNTSNQISHWDLGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAAINAGIIPLGNTSNQISHWDLGS
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE2 SFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAK
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE2 VEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAIIFKHIEGWSALDAIYFVVITLTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAIIFKHIEGWSALDAIYFVVITLTT
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE2 IGFGDYVAGGSDIEYLDFYKPVVWFWILVGLAYFAAVLSMIGDWLRVISKKTKEEVGEFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IGFGDYVAGGSDIEYLDFYKPVVWFWILVGLAYFAAVLSMIGDWLRVISKKTKEEVGEFR
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE2 AHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSIKRKLSAELAGNHNQELTPCRRTLSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSIKRKLSAELAGNHNQELTPCRRTLSV
280 290 300 310 320 330
390 400 410 420
pF1KE2 NHLTSERDVLPPLLKTESIYLNGLTPHCAGEEIAVIENIK
::::::::::::::::::::::::::::::::::::::::
XP_011 NHLTSERDVLPPLLKTESIYLNGLTPHCAGEEIAVIENIK
340 350 360 370
>>XP_011507825 (OMIM: 603219) potassium channel subfamil (370 aa)
initn: 2396 init1: 2396 opt: 2396 Z-score: 2896.2 bits: 544.7 E(91410): 1.5e-154
Smith-Waterman score: 2396; 100.0% identity (100.0% similar) in 370 aa overlap (53-422:1-370)
30 40 50 60 70 80
pF1KE2 AAQNSKPRLSFSTKPTVLASRVESDTTINVMKWKTVSTIFLVVVLYLIIGATVFKALEQP
::::::::::::::::::::::::::::::
XP_011 MKWKTVSTIFLVVVLYLIIGATVFKALEQP
10 20 30
90 100 110 120 130 140
pF1KE2 HEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAAINAGIIPLGNTSNQISHWDLGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAAINAGIIPLGNTSNQISHWDLGS
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE2 SFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAK
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE2 VEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAIIFKHIEGWSALDAIYFVVITLTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAIIFKHIEGWSALDAIYFVVITLTT
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE2 IGFGDYVAGGSDIEYLDFYKPVVWFWILVGLAYFAAVLSMIGDWLRVISKKTKEEVGEFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IGFGDYVAGGSDIEYLDFYKPVVWFWILVGLAYFAAVLSMIGDWLRVISKKTKEEVGEFR
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE2 AHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSIKRKLSAELAGNHNQELTPCRRTLSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSIKRKLSAELAGNHNQELTPCRRTLSV
280 290 300 310 320 330
390 400 410 420
pF1KE2 NHLTSERDVLPPLLKTESIYLNGLTPHCAGEEIAVIENIK
::::::::::::::::::::::::::::::::::::::::
XP_011 NHLTSERDVLPPLLKTESIYLNGLTPHCAGEEIAVIENIK
340 350 360 370
>>XP_011507826 (OMIM: 603219) potassium channel subfamil (370 aa)
initn: 2396 init1: 2396 opt: 2396 Z-score: 2896.2 bits: 544.7 E(91410): 1.5e-154
Smith-Waterman score: 2396; 100.0% identity (100.0% similar) in 370 aa overlap (53-422:1-370)
30 40 50 60 70 80
pF1KE2 AAQNSKPRLSFSTKPTVLASRVESDTTINVMKWKTVSTIFLVVVLYLIIGATVFKALEQP
::::::::::::::::::::::::::::::
XP_011 MKWKTVSTIFLVVVLYLIIGATVFKALEQP
10 20 30
90 100 110 120 130 140
pF1KE2 HEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAAINAGIIPLGNTSNQISHWDLGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAAINAGIIPLGNTSNQISHWDLGS
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE2 SFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAK
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE2 VEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAIIFKHIEGWSALDAIYFVVITLTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAIIFKHIEGWSALDAIYFVVITLTT
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE2 IGFGDYVAGGSDIEYLDFYKPVVWFWILVGLAYFAAVLSMIGDWLRVISKKTKEEVGEFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IGFGDYVAGGSDIEYLDFYKPVVWFWILVGLAYFAAVLSMIGDWLRVISKKTKEEVGEFR
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE2 AHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSIKRKLSAELAGNHNQELTPCRRTLSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSIKRKLSAELAGNHNQELTPCRRTLSV
280 290 300 310 320 330
390 400 410 420
pF1KE2 NHLTSERDVLPPLLKTESIYLNGLTPHCAGEEIAVIENIK
::::::::::::::::::::::::::::::::::::::::
XP_011 NHLTSERDVLPPLLKTESIYLNGLTPHCAGEEIAVIENIK
340 350 360 370
>>NP_066984 (OMIM: 605873) potassium channel subfamily K (538 aa)
initn: 1142 init1: 1064 opt: 1583 Z-score: 1912.6 bits: 363.3 E(91410): 9.2e-100
Smith-Waterman score: 1584; 62.7% identity (83.5% similar) in 394 aa overlap (9-380:7-399)
10 20 30 40
pF1KE2 MMNPRAKRDFYL------AAPDLLDPKSA--------AQNSKPRLSFSTKPTVLASRVES
::.: :: . .:::: : . ::::.:.. ::.: :.:.
NP_066 MFFLYTDFFLSLVAVPAAAPVCQPKSATNGQPPAPAPTPTPRLSISSRATVVA-RMEG
10 20 30 40 50
50 60 70 80 90 100
pF1KE2 DTT---INVMKWKTVSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHS
. .::::::: .::.:::.::. :. ::.::::: : ::..::...: :. .:
NP_066 TSQGGLQTVMKWKTVVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHV
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE2 CVNSTELDELIQQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRT
::. ::. :::. . : :::. :.::.::. :::::::.::::::::::::.:::.: :
NP_066 CVSPQELETLIQHALDADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPST
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE2 EGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTI
::::::::.::..:::::::::::.::::::::::.::.:: .: : .:::::::.::::
NP_066 EGGKIFCILYAIFGIPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTI
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE2 IFILFGCVLFVALPAIIFKHIEGWSALDAIYFVVITLTTIGFGDYVAGGS-DIEYLDFYK
.::: ::..::..::.:::.::::.::..:::::.::::.::::.::::. :.: ..::
NP_066 LFILAGCIVFVTIPAVIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGGNAGINYREWYK
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE2 PVVWFWILVGLAYFAAVLSMIGDWLRVISKKTKEEVGEFRAHAAEWTANVTAEFKETRRR
:.:::::::::::::::::::::::::.::::::::::..:::::: :::::::.:::::
NP_066 PLVWFWILVGLAYFAAVLSMIGDWLRVLSKKTKEEVGEIKAHAAEWKANVTAEFRETRRR
300 310 320 330 340 350
350 360 370 380 390
pF1KE2 LSVEIYDKFQRATSIK----RKLSAELAGNHNQELTPCRRTLSVNHLTSERDVLPPLLKT
:::::.::.:::..:. :.:. . .. . :.: .:..
NP_066 LSVEIHDKLQRAATIRSMERRRLGLDQRAHSLDMLSPEKRSVFAALDTGRFKASSQESIN
360 370 380 390 400 410
400 410 420
pF1KE2 ESIYLNGLTPHCAGEEIAVIENIK
NP_066 NRPNNLRLKGPEQLNKHGQGASEDNIINKFGSTSRLTKRKNKDLKKTLPEDVQKIYKTFR
420 430 440 450 460 470
>>NP_612191 (OMIM: 605873) potassium channel subfamily K (543 aa)
initn: 1142 init1: 1064 opt: 1583 Z-score: 1912.5 bits: 363.3 E(91410): 9.3e-100
Smith-Waterman score: 1583; 64.8% identity (86.4% similar) in 369 aa overlap (20-380:37-404)
10 20 30 40
pF1KE2 MMNPRAKRDFYLAAPDLLDPKSAAQNSKPRLSFSTKPTVLASRVESDTT
: . : . ::::.:.. ::.: :.:. .
NP_612 GDRTEGCRSDSVAVPAAAPVCQPKSATNGQPPAPAPTPTPRLSISSRATVVA-RMEGTSQ
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE2 ---INVMKWKTVSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVN
.::::::: .::.:::.::. :. ::.::::: : ::..::...: :. .: ::.
NP_612 GGLQTVMKWKTVVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVS
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE2 STELDELIQQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGG
::. :::. . : :::. :.::.::. :::::::.::::::::::::.:::.: ::::
NP_612 PQELETLIQHALDADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGG
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE2 KIFCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFI
:::::.::..:::::::::::.::::::::::.::.:: .: : .:::::::.::::.::
NP_612 KIFCILYAIFGIPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFI
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE2 LFGCVLFVALPAIIFKHIEGWSALDAIYFVVITLTTIGFGDYVAGGS-DIEYLDFYKPVV
: ::..::..::.:::.::::.::..:::::.::::.::::.::::. :.: ..:::.:
NP_612 LAGCIVFVTIPAVIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGGNAGINYREWYKPLV
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE2 WFWILVGLAYFAAVLSMIGDWLRVISKKTKEEVGEFRAHAAEWTANVTAEFKETRRRLSV
::::::::::::::::::::::::.::::::::::..:::::: :::::::.::::::::
NP_612 WFWILVGLAYFAAVLSMIGDWLRVLSKKTKEEVGEIKAHAAEWKANVTAEFRETRRRLSV
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE2 EIYDKFQRATSIK----RKLSAELAGNHNQELTPCRRTLSVNHLTSERDVLPPLLKTESI
::.::.:::..:. :.:. . .. . :.: .:..
NP_612 EIHDKLQRAATIRSMERRRLGLDQRAHSLDMLSPEKRSVFAALDTGRFKASSQESINNRP
370 380 390 400 410 420
410 420
pF1KE2 YLNGLTPHCAGEEIAVIENIK
NP_612 NNLRLKGPEQLNKHGQGASEDNIINKFGSTSRLTKRKNKDLKKTLPEDVQKIYKTFRNYS
430 440 450 460 470 480
422 residues in 1 query sequences
64704883 residues in 91410 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Jul 3 14:59:25 2018 done: Tue Jul 3 14:59:26 2018
Total Scan time: 3.800 Total Display time: 0.100
Function used was FASTA [36.3.4 Apr, 2011]