FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE2724, 199 aa
  1>>>pF1KE2724     199 - 199 aa - 199 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.4350+/-0.000698; mu= 12.2665+/- 0.042
 mean_var=57.5414+/-11.545, 0's: 0 Z-trim(108.5): 13  B-trim: 0 in 0/51
 Lambda= 0.169077
 statistics sampled from 10274 (10283) to 10274 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.716), E-opt: 0.2 (0.316), width:  16
 Scan time:  0.920

The best scores are:                                      opt bits E(32554)
CCDS6650.1 NMRK1 gene_id:54981|Hs108|chr9          ( 199) 1339 334.4 2.8e-92
CCDS83374.1 NMRK1 gene_id:54981|Hs108|chr9         ( 203) 1284 321.0 3.2e-88
CCDS12115.1 NMRK2 gene_id:27231|Hs108|chr19        ( 230)  715 182.2 2.1e-46
CCDS74259.1 NMRK2 gene_id:27231|Hs108|chr19        ( 235)  695 177.3 6.4e-45
CCDS47981.1 NMRK1 gene_id:54981|Hs108|chr9         ( 175)  679 173.4 7.3e-44


>>CCDS6650.1 NMRK1 gene_id:54981|Hs108|chr9               (199 aa)
 initn: 1339 init1: 1339 opt: 1339  Z-score: 1770.1  bits: 334.4 E(32554): 2.8e-92
Smith-Waterman score: 1339; 100.0% identity (100.0% similar) in 199 aa overlap (1-199:1-199)

               10        20        30        40        50        60
pF1KE2 MKTFIIGISGVTNSGKTTLAKNLQKHLPNCSVISQDDFFKPESEIETDKNGFLQYDVLEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS66 MKTFIIGISGVTNSGKTTLAKNLQKHLPNCSVISQDDFFKPESEIETDKNGFLQYDVLEA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 LNMEKMMSAISCWMESARHSVVSTDQESAEEIPILIIEGFLLFNYKPLDTIWNRSYFLTI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS66 LNMEKMMSAISCWMESARHSVVSTDQESAEEIPILIIEGFLLFNYKPLDTIWNRSYFLTI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 PYEECKRRRSTRVYQPPDSPGYFDGHVWPMYLKYRQEMQDITWEVVYLDGTKSEEDLFLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS66 PYEECKRRRSTRVYQPPDSPGYFDGHVWPMYLKYRQEMQDITWEVVYLDGTKSEEDLFLQ
              130       140       150       160       170       180

              190         
pF1KE2 VYEDLIQELAKQKCLQVTA
       :::::::::::::::::::
CCDS66 VYEDLIQELAKQKCLQVTA
              190         

>>CCDS83374.1 NMRK1 gene_id:54981|Hs108|chr9              (203 aa)
 initn: 1284 init1: 1284 opt: 1284  Z-score: 1697.4  bits: 321.0 E(32554): 3.2e-88
Smith-Waterman score: 1284; 99.5% identity (99.5% similar) in 192 aa overlap (8-199:12-203)

                   10        20        30        40        50      
pF1KE2     MKTFIIGISGVTNSGKTTLAKNLQKHLPNCSVISQDDFFKPESEIETDKNGFLQYD
                  :: ::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 MGKRRHRRGNVISCVTNSGKTTLAKNLQKHLPNCSVISQDDFFKPESEIETDKNGFLQYD
               10        20        30        40        50        60

         60        70        80        90       100       110      
pF1KE2 VLEALNMEKMMSAISCWMESARHSVVSTDQESAEEIPILIIEGFLLFNYKPLDTIWNRSY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 VLEALNMEKMMSAISCWMESARHSVVSTDQESAEEIPILIIEGFLLFNYKPLDTIWNRSY
               70        80        90       100       110       120

        120       130       140       150       160       170      
pF1KE2 FLTIPYEECKRRRSTRVYQPPDSPGYFDGHVWPMYLKYRQEMQDITWEVVYLDGTKSEED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 FLTIPYEECKRRRSTRVYQPPDSPGYFDGHVWPMYLKYRQEMQDITWEVVYLDGTKSEED
              130       140       150       160       170       180

        180       190         
pF1KE2 LFLQVYEDLIQELAKQKCLQVTA
       :::::::::::::::::::::::
CCDS83 LFLQVYEDLIQELAKQKCLQVTA
              190       200   

>>CCDS12115.1 NMRK2 gene_id:27231|Hs108|chr19             (230 aa)
 initn: 697 init1: 434 opt: 715  Z-score: 946.4  bits: 182.2 E(32554): 2.1e-46
Smith-Waterman score: 715; 57.0% identity (77.7% similar) in 193 aa overlap (1-189:1-191)

               10        20        30        40        50        60
pF1KE2 MKTFIIGISGVTNSGKTTLAKNLQKHLPNCSVISQDDFFKPESEIETDKNGFLQYDVLEA
       :: .:.::.:.::.:::::...: . :::: :: :::::::...: . ..:: :.::::.
CCDS12 MK-LIVGIGGMTNGGKTTLTNSLLRALPNCCVIHQDDFFKPQDQIAVGEDGFKQWDVLES
                10        20        30        40        50         

               70            80        90       100       110      
pF1KE2 LNMEKMMSAISCWMES----ARHSVVSTDQESAEEIPILIIEGFLLFNYKPLDTIWNRSY
       :.:: :..... :. :    ::   ::. :  : .  ::..:::::..::::  ...: :
CCDS12 LDMEAMLDTVQAWLSSPQKFARAHGVSV-QPEASDTHILLLEGFLLYSYKPLVDLYSRRY
      60        70        80         90       100       110        

        120       130       140       150       160       170      
pF1KE2 FLTIPYEECKRRRSTRVYQPPDSPGYFDGHVWPMYLKYRQEMQDITWEVVYLDGTKSEED
       :::.:::::: ::::: :  :: :: ::::::::: ::::::.    ::::::: ::.:.
CCDS12 FLTVPYEECKWRRSTRNYTVPDPPGLFDGHVWPMYQKYRQEMEANGVEVVYLDGMKSREE
      120       130       140       150       160       170        

        180       190                                      
pF1KE2 LFLQVYEDLIQELAKQKCLQVTA                             
       :: .: ::. . :                                       
CCDS12 LFREVLEDIQNSLLNRSQESAPSPARPARTQGPGRGCGHRTARPAASQQDSM
      180       190       200       210       220       230

>>CCDS74259.1 NMRK2 gene_id:27231|Hs108|chr19             (235 aa)
 initn: 673 init1: 434 opt: 695  Z-score: 919.9  bits: 177.3 E(32554): 6.4e-45
Smith-Waterman score: 695; 55.6% identity (75.8% similar) in 198 aa overlap (1-189:1-196)

               10        20        30        40             50     
pF1KE2 MKTFIIGISGVTNSGKTTLAKNLQKHLPNCSVISQDDFFK-----PESEIETDKNGFLQY
       :: .:.::.:.::.:::::...: . :::: :: ::::::     :...: . ..:: :.
CCDS74 MK-LIVGIGGMTNGGKTTLTNSLLRALPNCCVIHQDDFFKAPLFQPQDQIAVGEDGFKQW
                10        20        30        40        50         

          60        70            80        90       100       110 
pF1KE2 DVLEALNMEKMMSAISCWMES----ARHSVVSTDQESAEEIPILIIEGFLLFNYKPLDTI
       ::::.:.:: :..... :. :    ::   ::. :  : .  ::..:::::..::::  .
CCDS74 DVLESLDMEAMLDTVQAWLSSPQKFARAHGVSV-QPEASDTHILLLEGFLLYSYKPLVDL
      60        70        80        90        100       110        

             120       130       140       150       160       170 
pF1KE2 WNRSYFLTIPYEECKRRRSTRVYQPPDSPGYFDGHVWPMYLKYRQEMQDITWEVVYLDGT
       ..: ::::.:::::: ::::: :  :: :: ::::::::: ::::::.    ::::::: 
CCDS74 YSRRYFLTVPYEECKWRRSTRNYTVPDPPGLFDGHVWPMYQKYRQEMEANGVEVVYLDGM
      120       130       140       150       160       170        

             180       190                                      
pF1KE2 KSEEDLFLQVYEDLIQELAKQKCLQVTA                             
       ::.:.:: .: ::. . :                                       
CCDS74 KSREELFREVLEDIQNSLLNRSQESAPSPARPARTQGPGRGCGHRTARPAASQQDSM
      180       190       200       210       220       230     

>>CCDS47981.1 NMRK1 gene_id:54981|Hs108|chr9              (175 aa)
 initn: 1147 init1: 679 opt: 679  Z-score: 900.9  bits: 173.4 E(32554): 7.3e-44
Smith-Waterman score: 1103; 87.4% identity (87.9% similar) in 199 aa overlap (1-199:1-175)

               10        20        30        40        50        60
pF1KE2 MKTFIIGISGVTNSGKTTLAKNLQKHLPNCSVISQDDFFKPESEIETDKNGFLQYDVLEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 MKTFIIGISGVTNSGKTTLAKNLQKHLPNCSVISQDDFFKPESEIETDKNGFLQYDVLEA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 LNMEKMMSAISCWMESARHSVVSTDQESAEEIPILIIEGFLLFNYKPLDTIWNRSYFLTI
       :::::::::::::::::::::::::::::::::::::::::::::               
CCDS47 LNMEKMMSAISCWMESARHSVVSTDQESAEEIPILIIEGFLLFNY---------------
               70        80        90       100                    

              130       140       150       160       170       180
pF1KE2 PYEECKRRRSTRVYQPPDSPGYFDGHVWPMYLKYRQEMQDITWEVVYLDGTKSEEDLFLQ
                .::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 ---------NTRVYQPPDSPGYFDGHVWPMYLKYRQEMQDITWEVVYLDGTKSEEDLFLQ
                  110       120       130       140       150      

              190         
pF1KE2 VYEDLIQELAKQKCLQVTA
       :::::::::::::::::::
CCDS47 VYEDLIQELAKQKCLQVTA
        160       170     




199 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Wed Jun 13 19:13:01 2018 done: Wed Jun 13 19:13:02 2018
 Total Scan time:  0.920 Total Display time:  0.020

Function used was FASTA [36.3.4 Apr, 2011]