Result of FASTA (omim) for
pFN21AE2720
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2720, 308 aa
1>>>pF1KE2720 308 - 308 aa - 308 aa
Library: /omim/omim.rfq.tfa
64536644 residues in 91102 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.2346+/-0.000361; mu= 12.1253+/- 0.022
mean_var=110.0782+/-21.604, 0's: 0 Z-trim(115.7): 10 B-trim: 65 in 1/53
Lambda= 0.122243
statistics sampled from 27258 (27268) to 27258 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.676), E-opt: 0.2 (0.299), width: 16
Scan time: 3.490
The best scores are: opt bits E(91102)
NP_835368 (OMIM: 602589) alpha-(1,6)-fucosyltransf ( 575) 1917 349.0 1.4e-95
NP_835369 (OMIM: 602589) alpha-(1,6)-fucosyltransf ( 575) 1917 349.0 1.4e-95
XP_016876627 (OMIM: 602589) alpha-(1,6)-fucosyltra ( 609) 1091 203.3 1.1e-51
XP_016876628 (OMIM: 602589) alpha-(1,6)-fucosyltra ( 609) 1091 203.3 1.1e-51
XP_016876626 (OMIM: 602589) alpha-(1,6)-fucosyltra ( 609) 1091 203.3 1.1e-51
XP_016876625 (OMIM: 602589) alpha-(1,6)-fucosyltra ( 609) 1091 203.3 1.1e-51
XP_016876629 (OMIM: 602589) alpha-(1,6)-fucosyltra ( 546) 835 158.1 3.8e-38
NP_004471 (OMIM: 602589) alpha-(1,6)-fucosyltransf ( 412) 822 155.7 1.5e-37
XP_011534916 (OMIM: 602589) alpha-(1,6)-fucosyltra ( 344) 337 70.1 7.4e-12
>>NP_835368 (OMIM: 602589) alpha-(1,6)-fucosyltransferas (575 aa)
initn: 1917 init1: 1917 opt: 1917 Z-score: 1837.2 bits: 349.0 E(91102): 1.4e-95
Smith-Waterman score: 1917; 99.6% identity (100.0% similar) in 279 aa overlap (1-279:1-279)
10 20 30 40 50 60
pF1KE2 MRPWTGSWRWIMLILFAWGTLLFYIGGHLVRDNDHPDHSSRELSKILAKLERLKQQNEDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_835 MRPWTGSWRWIMLILFAWGTLLFYIGGHLVRDNDHPDHSSRELSKILAKLERLKQQNEDL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 RRMAESLRIPEGPIDQGPAIGRVRVLEEQLVKAKEQIENYKKQTRNGLGKDHEILRRRIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_835 RRMAESLRIPEGPIDQGPAIGRVRVLEEQLVKAKEQIENYKKQTRNGLGKDHEILRRRIE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 NGAKELWFFLQSELKKLKNLEGNELQRHADEFLLDLGHYERSIMTDLYYLSQTDGAGDWR
::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::
NP_835 NGAKELWFFLQSELKKLKNLEGNELQRHADEFLLDLGHHERSIMTDLYYLSQTDGAGDWR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 EKEAKDLTELVQRRITYLQNPKDCSKAKKLVCNINKGCGYGCQLHHVVYCFMIAYGTQRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_835 EKEAKDLTELVQRRITYLQNPKDCSKAKKLVCNINKGCGYGCQLHHVVYCFMIAYGTQRT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 LILESQNWRYATGGWETVFRPVSETCTDRSGISTGHWSGTPIMNLLVITLFPGQLDCTID
:::::::::::::::::::::::::::::::::::::::
NP_835 LILESQNWRYATGGWETVFRPVSETCTDRSGISTGHWSGEVKDKNVQVVELPIVDSLHPR
250 260 270 280 290 300
pF1KE2 TQKIHFVE
NP_835 PPYLPLAVPEDLADRLVRVHGDPAVWWVSQFVKYLIRPQPWLEKEIEEATKKLGFKHPVI
310 320 330 340 350 360
>>NP_835369 (OMIM: 602589) alpha-(1,6)-fucosyltransferas (575 aa)
initn: 1917 init1: 1917 opt: 1917 Z-score: 1837.2 bits: 349.0 E(91102): 1.4e-95
Smith-Waterman score: 1917; 99.6% identity (100.0% similar) in 279 aa overlap (1-279:1-279)
10 20 30 40 50 60
pF1KE2 MRPWTGSWRWIMLILFAWGTLLFYIGGHLVRDNDHPDHSSRELSKILAKLERLKQQNEDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_835 MRPWTGSWRWIMLILFAWGTLLFYIGGHLVRDNDHPDHSSRELSKILAKLERLKQQNEDL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 RRMAESLRIPEGPIDQGPAIGRVRVLEEQLVKAKEQIENYKKQTRNGLGKDHEILRRRIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_835 RRMAESLRIPEGPIDQGPAIGRVRVLEEQLVKAKEQIENYKKQTRNGLGKDHEILRRRIE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 NGAKELWFFLQSELKKLKNLEGNELQRHADEFLLDLGHYERSIMTDLYYLSQTDGAGDWR
::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::
NP_835 NGAKELWFFLQSELKKLKNLEGNELQRHADEFLLDLGHHERSIMTDLYYLSQTDGAGDWR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 EKEAKDLTELVQRRITYLQNPKDCSKAKKLVCNINKGCGYGCQLHHVVYCFMIAYGTQRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_835 EKEAKDLTELVQRRITYLQNPKDCSKAKKLVCNINKGCGYGCQLHHVVYCFMIAYGTQRT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 LILESQNWRYATGGWETVFRPVSETCTDRSGISTGHWSGTPIMNLLVITLFPGQLDCTID
:::::::::::::::::::::::::::::::::::::::
NP_835 LILESQNWRYATGGWETVFRPVSETCTDRSGISTGHWSGEVKDKNVQVVELPIVDSLHPR
250 260 270 280 290 300
pF1KE2 TQKIHFVE
NP_835 PPYLPLAVPEDLADRLVRVHGDPAVWWVSQFVKYLIRPQPWLEKEIEEATKKLGFKHPVI
310 320 330 340 350 360
>>XP_016876627 (OMIM: 602589) alpha-(1,6)-fucosyltransfe (609 aa)
initn: 1091 init1: 1091 opt: 1091 Z-score: 1049.6 bits: 203.3 E(91102): 1.1e-51
Smith-Waterman score: 1839; 88.8% identity (89.1% similar) in 313 aa overlap (1-279:1-313)
10 20 30 40 50 60
pF1KE2 MRPWTGSWRWIMLILFAWGTLLFYIGGHLVRDNDHPDHSSRELSKILAKLERLKQQNEDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRPWTGSWRWIMLILFAWGTLLFYIGGHLVRDNDHPDHSSRELSKILAKLERLKQQNEDL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 RRMAESLRIPEGPIDQGPAIGRVRVLEEQLVKAKEQIENYKKQTRNGLGKDHEILRRRIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRMAESLRIPEGPIDQGPAIGRVRVLEEQLVKAKEQIENYKKQTRNGLGKDHEILRRRIE
70 80 90 100 110 120
130 140 150 160
pF1KE2 NGAKELWFFLQSELKKLKNLEGNELQRHADEFLLDLGHYER-------------------
::::::::::::::::::::::::::::::::::::::.::
XP_016 NGAKELWFFLQSELKKLKNLEGNELQRHADEFLLDLGHHERILMAITVSLVNNKRKIVVL
130 140 150 160 170 180
170 180 190 200
pF1KE2 ---------------SIMTDLYYLSQTDGAGDWREKEAKDLTELVQRRITYLQNPKDCSK
:::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQPTTVKRKRITPYKSIMTDLYYLSQTDGAGDWREKEAKDLTELVQRRITYLQNPKDCSK
190 200 210 220 230 240
210 220 230 240 250 260
pF1KE2 AKKLVCNINKGCGYGCQLHHVVYCFMIAYGTQRTLILESQNWRYATGGWETVFRPVSETC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKKLVCNINKGCGYGCQLHHVVYCFMIAYGTQRTLILESQNWRYATGGWETVFRPVSETC
250 260 270 280 290 300
270 280 290 300
pF1KE2 TDRSGISTGHWSGTPIMNLLVITLFPGQLDCTIDTQKIHFVE
:::::::::::::
XP_016 TDRSGISTGHWSGEVKDKNVQVVELPIVDSLHPRPPYLPLAVPEDLADRLVRVHGDPAVW
310 320 330 340 350 360
>>XP_016876628 (OMIM: 602589) alpha-(1,6)-fucosyltransfe (609 aa)
initn: 1091 init1: 1091 opt: 1091 Z-score: 1049.6 bits: 203.3 E(91102): 1.1e-51
Smith-Waterman score: 1839; 88.8% identity (89.1% similar) in 313 aa overlap (1-279:1-313)
10 20 30 40 50 60
pF1KE2 MRPWTGSWRWIMLILFAWGTLLFYIGGHLVRDNDHPDHSSRELSKILAKLERLKQQNEDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRPWTGSWRWIMLILFAWGTLLFYIGGHLVRDNDHPDHSSRELSKILAKLERLKQQNEDL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 RRMAESLRIPEGPIDQGPAIGRVRVLEEQLVKAKEQIENYKKQTRNGLGKDHEILRRRIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRMAESLRIPEGPIDQGPAIGRVRVLEEQLVKAKEQIENYKKQTRNGLGKDHEILRRRIE
70 80 90 100 110 120
130 140 150 160
pF1KE2 NGAKELWFFLQSELKKLKNLEGNELQRHADEFLLDLGHYER-------------------
::::::::::::::::::::::::::::::::::::::.::
XP_016 NGAKELWFFLQSELKKLKNLEGNELQRHADEFLLDLGHHERILMAITVSLVNNKRKIVVL
130 140 150 160 170 180
170 180 190 200
pF1KE2 ---------------SIMTDLYYLSQTDGAGDWREKEAKDLTELVQRRITYLQNPKDCSK
:::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQPTTVKRKRITPYKSIMTDLYYLSQTDGAGDWREKEAKDLTELVQRRITYLQNPKDCSK
190 200 210 220 230 240
210 220 230 240 250 260
pF1KE2 AKKLVCNINKGCGYGCQLHHVVYCFMIAYGTQRTLILESQNWRYATGGWETVFRPVSETC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKKLVCNINKGCGYGCQLHHVVYCFMIAYGTQRTLILESQNWRYATGGWETVFRPVSETC
250 260 270 280 290 300
270 280 290 300
pF1KE2 TDRSGISTGHWSGTPIMNLLVITLFPGQLDCTIDTQKIHFVE
:::::::::::::
XP_016 TDRSGISTGHWSGEVKDKNVQVVELPIVDSLHPRPPYLPLAVPEDLADRLVRVHGDPAVW
310 320 330 340 350 360
>>XP_016876626 (OMIM: 602589) alpha-(1,6)-fucosyltransfe (609 aa)
initn: 1091 init1: 1091 opt: 1091 Z-score: 1049.6 bits: 203.3 E(91102): 1.1e-51
Smith-Waterman score: 1839; 88.8% identity (89.1% similar) in 313 aa overlap (1-279:1-313)
10 20 30 40 50 60
pF1KE2 MRPWTGSWRWIMLILFAWGTLLFYIGGHLVRDNDHPDHSSRELSKILAKLERLKQQNEDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRPWTGSWRWIMLILFAWGTLLFYIGGHLVRDNDHPDHSSRELSKILAKLERLKQQNEDL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 RRMAESLRIPEGPIDQGPAIGRVRVLEEQLVKAKEQIENYKKQTRNGLGKDHEILRRRIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRMAESLRIPEGPIDQGPAIGRVRVLEEQLVKAKEQIENYKKQTRNGLGKDHEILRRRIE
70 80 90 100 110 120
130 140 150 160
pF1KE2 NGAKELWFFLQSELKKLKNLEGNELQRHADEFLLDLGHYER-------------------
::::::::::::::::::::::::::::::::::::::.::
XP_016 NGAKELWFFLQSELKKLKNLEGNELQRHADEFLLDLGHHERILMAITVSLVNNKRKIVVL
130 140 150 160 170 180
170 180 190 200
pF1KE2 ---------------SIMTDLYYLSQTDGAGDWREKEAKDLTELVQRRITYLQNPKDCSK
:::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQPTTVKRKRITPYKSIMTDLYYLSQTDGAGDWREKEAKDLTELVQRRITYLQNPKDCSK
190 200 210 220 230 240
210 220 230 240 250 260
pF1KE2 AKKLVCNINKGCGYGCQLHHVVYCFMIAYGTQRTLILESQNWRYATGGWETVFRPVSETC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKKLVCNINKGCGYGCQLHHVVYCFMIAYGTQRTLILESQNWRYATGGWETVFRPVSETC
250 260 270 280 290 300
270 280 290 300
pF1KE2 TDRSGISTGHWSGTPIMNLLVITLFPGQLDCTIDTQKIHFVE
:::::::::::::
XP_016 TDRSGISTGHWSGEVKDKNVQVVELPIVDSLHPRPPYLPLAVPEDLADRLVRVHGDPAVW
310 320 330 340 350 360
>>XP_016876625 (OMIM: 602589) alpha-(1,6)-fucosyltransfe (609 aa)
initn: 1091 init1: 1091 opt: 1091 Z-score: 1049.6 bits: 203.3 E(91102): 1.1e-51
Smith-Waterman score: 1839; 88.8% identity (89.1% similar) in 313 aa overlap (1-279:1-313)
10 20 30 40 50 60
pF1KE2 MRPWTGSWRWIMLILFAWGTLLFYIGGHLVRDNDHPDHSSRELSKILAKLERLKQQNEDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRPWTGSWRWIMLILFAWGTLLFYIGGHLVRDNDHPDHSSRELSKILAKLERLKQQNEDL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 RRMAESLRIPEGPIDQGPAIGRVRVLEEQLVKAKEQIENYKKQTRNGLGKDHEILRRRIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRMAESLRIPEGPIDQGPAIGRVRVLEEQLVKAKEQIENYKKQTRNGLGKDHEILRRRIE
70 80 90 100 110 120
130 140 150 160
pF1KE2 NGAKELWFFLQSELKKLKNLEGNELQRHADEFLLDLGHYER-------------------
::::::::::::::::::::::::::::::::::::::.::
XP_016 NGAKELWFFLQSELKKLKNLEGNELQRHADEFLLDLGHHERILMAITVSLVNNKRKIVVL
130 140 150 160 170 180
170 180 190 200
pF1KE2 ---------------SIMTDLYYLSQTDGAGDWREKEAKDLTELVQRRITYLQNPKDCSK
:::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQPTTVKRKRITPYKSIMTDLYYLSQTDGAGDWREKEAKDLTELVQRRITYLQNPKDCSK
190 200 210 220 230 240
210 220 230 240 250 260
pF1KE2 AKKLVCNINKGCGYGCQLHHVVYCFMIAYGTQRTLILESQNWRYATGGWETVFRPVSETC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKKLVCNINKGCGYGCQLHHVVYCFMIAYGTQRTLILESQNWRYATGGWETVFRPVSETC
250 260 270 280 290 300
270 280 290 300
pF1KE2 TDRSGISTGHWSGTPIMNLLVITLFPGQLDCTIDTQKIHFVE
:::::::::::::
XP_016 TDRSGISTGHWSGEVKDKNVQVVELPIVDSLHPRPPYLPLAVPEDLADRLVRVHGDPAVW
310 320 330 340 350 360
>>XP_016876629 (OMIM: 602589) alpha-(1,6)-fucosyltransfe (546 aa)
initn: 835 init1: 835 opt: 835 Z-score: 806.3 bits: 158.1 E(91102): 3.8e-38
Smith-Waterman score: 1373; 85.1% identity (86.3% similar) in 248 aa overlap (66-279:3-250)
40 50 60 70 80 90
pF1KE2 PDHSSRELSKILAKLERLKQQNEDLRRMAESLRIPEGPIDQGPAIGRVRVLEEQLVKAKE
..::::::::::::::::::::::::::::
XP_016 MWNVRIPEGPIDQGPAIGRVRVLEEQLVKAKE
10 20 30
100 110 120 130 140 150
pF1KE2 QIENYKKQTRNGLGKDHEILRRRIENGAKELWFFLQSELKKLKNLEGNELQRHADEFLLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QIENYKKQTRNGLGKDHEILRRRIENGAKELWFFLQSELKKLKNLEGNELQRHADEFLLD
40 50 60 70 80 90
160 170 180
pF1KE2 LGHYER----------------------------------SIMTDLYYLSQTDGAGDWRE
:::.:: ::::::::::::::::::::
XP_016 LGHHERILMAITVSLVNNKRKIVVLAQPTTVKRKRITPYKSIMTDLYYLSQTDGAGDWRE
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE2 KEAKDLTELVQRRITYLQNPKDCSKAKKLVCNINKGCGYGCQLHHVVYCFMIAYGTQRTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KEAKDLTELVQRRITYLQNPKDCSKAKKLVCNINKGCGYGCQLHHVVYCFMIAYGTQRTL
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE2 ILESQNWRYATGGWETVFRPVSETCTDRSGISTGHWSGTPIMNLLVITLFPGQLDCTIDT
::::::::::::::::::::::::::::::::::::::
XP_016 ILESQNWRYATGGWETVFRPVSETCTDRSGISTGHWSGEVKDKNVQVVELPIVDSLHPRP
220 230 240 250 260 270
pF1KE2 QKIHFVE
XP_016 PYLPLAVPEDLADRLVRVHGDPAVWWVSQFVKYLIRPQPWLEKEIEEATKKLGFKHPVIG
280 290 300 310 320 330
>>NP_004471 (OMIM: 602589) alpha-(1,6)-fucosyltransferas (412 aa)
initn: 822 init1: 822 opt: 822 Z-score: 795.5 bits: 155.7 E(91102): 1.5e-37
Smith-Waterman score: 822; 100.0% identity (100.0% similar) in 116 aa overlap (164-279:1-116)
140 150 160 170 180 190
pF1KE2 LKKLKNLEGNELQRHADEFLLDLGHYERSIMTDLYYLSQTDGAGDWREKEAKDLTELVQR
::::::::::::::::::::::::::::::
NP_004 MTDLYYLSQTDGAGDWREKEAKDLTELVQR
10 20 30
200 210 220 230 240 250
pF1KE2 RITYLQNPKDCSKAKKLVCNINKGCGYGCQLHHVVYCFMIAYGTQRTLILESQNWRYATG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RITYLQNPKDCSKAKKLVCNINKGCGYGCQLHHVVYCFMIAYGTQRTLILESQNWRYATG
40 50 60 70 80 90
260 270 280 290 300
pF1KE2 GWETVFRPVSETCTDRSGISTGHWSGTPIMNLLVITLFPGQLDCTIDTQKIHFVE
::::::::::::::::::::::::::
NP_004 GWETVFRPVSETCTDRSGISTGHWSGEVKDKNVQVVELPIVDSLHPRPPYLPLAVPEDLA
100 110 120 130 140 150
>>XP_011534916 (OMIM: 602589) alpha-(1,6)-fucosyltransfe (344 aa)
initn: 337 init1: 337 opt: 337 Z-score: 334.3 bits: 70.1 E(91102): 7.4e-12
Smith-Waterman score: 337; 100.0% identity (100.0% similar) in 48 aa overlap (232-279:1-48)
210 220 230 240 250 260
pF1KE2 KDCSKAKKLVCNINKGCGYGCQLHHVVYCFMIAYGTQRTLILESQNWRYATGGWETVFRP
::::::::::::::::::::::::::::::
XP_011 MIAYGTQRTLILESQNWRYATGGWETVFRP
10 20 30
270 280 290 300
pF1KE2 VSETCTDRSGISTGHWSGTPIMNLLVITLFPGQLDCTIDTQKIHFVE
::::::::::::::::::
XP_011 VSETCTDRSGISTGHWSGEVKDKNVQVVELPIVDSLHPRPPYLPLAVPEDLADRLVRVHG
40 50 60 70 80 90
308 residues in 1 query sequences
64536644 residues in 91102 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Jun 6 17:55:32 2018 done: Wed Jun 6 17:55:33 2018
Total Scan time: 3.490 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]