Result of FASTA (omim) for
pFN21AE2704
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2704, 1349 aa
1>>>pF1KE2704 1349 - 1349 aa - 1349 aa
Library: /omim/omim.rfq.tfa
63214209 residues in 88908 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.5171+/-0.000505; mu= -5.0561+/- 0.032
mean_var=366.1038+/-77.975, 0's: 0 Z-trim(119.7): 90 B-trim: 1509 in 2/51
Lambda= 0.067030
statistics sampled from 34716 (34809) to 34716 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.701), E-opt: 0.2 (0.392), width: 16
Scan time: 19.410
The best scores are: opt bits E(88908)
NP_005349 (OMIM: 604362) LIM domain only protein 7 (1349) 8922 878.2 0
XP_016876090 (OMIM: 604362) PREDICTED: LIM domain (1304) 6522 646.1 4.9e-184
XP_016876091 (OMIM: 604362) PREDICTED: LIM domain (1304) 6522 646.1 4.9e-184
NP_001317512 (OMIM: 604362) LIM domain only protei (1398) 6522 646.2 5.1e-184
XP_011533384 (OMIM: 604362) PREDICTED: LIM domain (1466) 6522 646.2 5.3e-184
NP_001293009 (OMIM: 604362) LIM domain only protei (1631) 6522 646.2 5.8e-184
XP_016876076 (OMIM: 604362) PREDICTED: LIM domain (1320) 6479 642.0 8.8e-183
XP_016876068 (OMIM: 604362) PREDICTED: LIM domain (1482) 6479 642.0 9.6e-183
XP_016876067 (OMIM: 604362) PREDICTED: LIM domain (1490) 6037 599.3 7.1e-170
XP_016876092 (OMIM: 604362) PREDICTED: LIM domain (1291) 5959 591.7 1.2e-167
XP_016876079 (OMIM: 604362) PREDICTED: LIM domain (1291) 5959 591.7 1.2e-167
NP_056667 (OMIM: 604362) LIM domain only protein 7 (1385) 5959 591.7 1.2e-167
XP_016876087 (OMIM: 604362) PREDICTED: LIM domain (1385) 5959 591.7 1.2e-167
XP_011533388 (OMIM: 604362) PREDICTED: LIM domain (1385) 5959 591.7 1.2e-167
XP_016876078 (OMIM: 604362) PREDICTED: LIM domain (1385) 5959 591.7 1.2e-167
XP_016876089 (OMIM: 604362) PREDICTED: LIM domain (1078) 3940 396.4 6.1e-109
XP_011533396 (OMIM: 604362) PREDICTED: LIM domain (1081) 3784 381.3 2.1e-104
XP_011533397 (OMIM: 604362) PREDICTED: LIM domain (1091) 3784 381.3 2.2e-104
XP_011533380 (OMIM: 604362) PREDICTED: LIM domain (1493) 3784 381.4 2.7e-104
XP_016876064 (OMIM: 604362) PREDICTED: LIM domain (1509) 3741 377.3 4.9e-103
XP_016876065 (OMIM: 604362) PREDICTED: LIM domain (1504) 3593 362.9 1e-98
XP_016876075 (OMIM: 604362) PREDICTED: LIM domain (1334) 3458 349.8 7.8e-95
XP_016876072 (OMIM: 604362) PREDICTED: LIM domain (1412) 3458 349.9 8.1e-95
XP_016876071 (OMIM: 604362) PREDICTED: LIM domain (1428) 3458 349.9 8.2e-95
XP_011533382 (OMIM: 604362) PREDICTED: LIM domain (1480) 3458 349.9 8.4e-95
XP_016876066 (OMIM: 604362) PREDICTED: LIM domain (1496) 3458 349.9 8.5e-95
XP_011533377 (OMIM: 604362) PREDICTED: LIM domain (1507) 3343 338.8 1.9e-91
XP_016876093 (OMIM: 604362) PREDICTED: LIM domain (1121) 3315 336.0 9.9e-91
XP_016876085 (OMIM: 604362) PREDICTED: LIM domain (1121) 3315 336.0 9.9e-91
XP_016876086 (OMIM: 604362) PREDICTED: LIM domain (1111) 3300 334.5 2.7e-90
XP_016876074 (OMIM: 604362) PREDICTED: LIM domain (1361) 3300 334.6 3.1e-90
XP_016876088 (OMIM: 604362) PREDICTED: LIM domain (1361) 3300 334.6 3.1e-90
XP_016876082 (OMIM: 604362) PREDICTED: LIM domain (1455) 3300 334.6 3.3e-90
XP_016876073 (OMIM: 604362) PREDICTED: LIM domain (1455) 3300 334.6 3.3e-90
XP_016876083 (OMIM: 604362) PREDICTED: LIM domain (1455) 3300 334.6 3.3e-90
XP_016876069 (OMIM: 604362) PREDICTED: LIM domain (1455) 3300 334.6 3.3e-90
XP_016876070 (OMIM: 604362) PREDICTED: LIM domain (1523) 3300 334.6 3.4e-90
XP_016876063 (OMIM: 604362) PREDICTED: LIM domain (1523) 3300 334.6 3.4e-90
XP_016876081 (OMIM: 604362) PREDICTED: LIM domain (1523) 3300 334.6 3.4e-90
XP_016876080 (OMIM: 604362) PREDICTED: LIM domain (1523) 3300 334.6 3.4e-90
XP_016876077 (OMIM: 604362) PREDICTED: LIM domain (1318) 3221 326.9 6.1e-88
>>NP_005349 (OMIM: 604362) LIM domain only protein 7 iso (1349 aa)
initn: 8922 init1: 8922 opt: 8922 Z-score: 4679.5 bits: 878.2 E(88908): 0
Smith-Waterman score: 8922; 100.0% identity (100.0% similar) in 1349 aa overlap (1-1349:1-1349)
10 20 30 40 50 60
pF1KE2 MKKIRICHIFTFYSWMSYDVLFQRTELGALEIWRQLICAHVCICVGWLYLRDRVCSKKDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MKKIRICHIFTFYSWMSYDVLFQRTELGALEIWRQLICAHVCICVGWLYLRDRVCSKKDI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 ILRTEQNSGRTILIKAVTEKNFETKDFRASLENGVLLCDLINKLKPGVIKKINRLSTPIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ILRTEQNSGRTILIKAVTEKNFETKDFRASLENGVLLCDLINKLKPGVIKKINRLSTPIA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 GLDNINVFLKACEQIGLKEAQLFHPGDLQDLSNRVTVKQEETDRRVKNVLITLYWLGRKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GLDNINVFLKACEQIGLKEAQLFHPGDLQDLSNRVTVKQEETDRRVKNVLITLYWLGRKA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 QSNPYYNGPHLNLKAFENLLGQALTKALEDSSFLKRSGRDSGYGDIWCPERGEFLAPPRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QSNPYYNGPHLNLKAFENLLGQALTKALEDSSFLKRSGRDSGYGDIWCPERGEFLAPPRH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 HKREDSFESLDSLGSRSLTSCSSDITLRGGREGFESDTDSEFTFKMQDYNKDDMSYRRIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 HKREDSFESLDSLGSRSLTSCSSDITLRGGREGFESDTDSEFTFKMQDYNKDDMSYRRIS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 AVEPKTALPFNRFLPNKSRQPSYVPAPLRKKKPDKHEDNRRSWASPVYTEADGTFSRLFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 AVEPKTALPFNRFLPNKSRQPSYVPAPLRKKKPDKHEDNRRSWASPVYTEADGTFSRLFQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 KIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 DLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 RPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 ASLSSLRSRSTQMESTRVSASLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ASLSSLRSRSTQMESTRVSASLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTMD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 DAWKYNGDVEDIKRTPNNVVSTPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPTSPFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DAWKYNGDVEDIKRTPNNVVSTPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPTSPFS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 SLSQDQAATSKATLSSTSGLDLMSESGEGEISPQREVSRSQDQFSDMRISINQTPGKSLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SLSQDQAATSKATLSSTSGLDLMSESGEGEISPQREVSRSQDQFSDMRISINQTPGKSLD
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 FGFTIKWDIPGIFVASVEAGSPAEFSQLQVDDEIIAINNTKFSYNDSKEWEEAMAKAQET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 FGFTIKWDIPGIFVASVEAGSPAEFSQLQVDDEIIAINNTKFSYNDSKEWEEAMAKAQET
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 GHLVMDVRRYGKAGSPETKWIDATSGIYNSEKSSNLSVTTDFSESLQSSNIESKEINGIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GHLVMDVRRYGKAGSPETKWIDATSGIYNSEKSSNLSVTTDFSESLQSSNIESKEINGIH
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 DESNAFESKASESISLKNLKRRSQFFEQGSSDSVVPDLPVPTISAPSRWVWDQEEERKRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DESNAFESKASESISLKNLKRRSQFFEQGSSDSVVPDLPVPTISAPSRWVWDQEEERKRQ
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 ERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREP
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 SLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 QEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIPKTEEASSGFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIPKTEEASSGFL
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 PGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQEM
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 RKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGESLDNLDSPRSNSWRQPPWLNQPTGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGESLDNLDSPRSNSWRQPPWLNQPTGF
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 YASSSVQDFSRPPPQLVSTSNRAYMRNPSSSVPPPSAGSVKTSTTGVATTQSPTPRSHSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 YASSSVQDFSRPPPQLVSTSNRAYMRNPSSSVPPPSAGSVKTSTTGVATTQSPTPRSHSP
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 SASQSGSQLRNRSVSGKRICSYCNNILGKGAAMIIESLGLCYHLHCFKCVACECDLGGSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SASQSGSQLRNRSVSGKRICSYCNNILGKGAAMIIESLGLCYHLHCFKCVACECDLGGSS
1270 1280 1290 1300 1310 1320
1330 1340
pF1KE2 SGAEVRIRNHQLYCNDCYLRFKSGRPTAM
:::::::::::::::::::::::::::::
NP_005 SGAEVRIRNHQLYCNDCYLRFKSGRPTAM
1330 1340
>>XP_016876090 (OMIM: 604362) PREDICTED: LIM domain only (1304 aa)
initn: 6512 init1: 6512 opt: 6522 Z-score: 3425.4 bits: 646.1 E(88908): 4.9e-184
Smith-Waterman score: 6537; 95.3% identity (96.6% similar) in 1059 aa overlap (291-1349:258-1304)
270 280 290 300 310 320
pF1KE2 CSSDITLRGGREGFESDTDSEFTFKMQDYNKDDMSYRRISAVEPKTALPFNRFLPNKSRQ
:::: :.:.. . :..: :
XP_016 AKFLCVLERTCPSKEKSNSCRILVPSYRQKKDDMLTRKIQSWKLGTTVP-----PI----
230 240 250 260 270
330 340 350 360 370 380
pF1KE2 PSYVPAPLRKKKPDKHEDNRRSWASPVYTEADGTFSRLFQKIYGENGSKSMSDVSAEDVQ
:..:.: . . : :. :: . . ::::::::::::::::::::::::
XP_016 -SFTPGPCSEADLKRWEAIRE--ASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQ
280 290 300 310 320 330
390 400 410 420 430 440
pF1KE2 NLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKS
340 350 360 370 380 390
450 460 470 480 490 500
pF1KE2 KRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEK
400 410 420 430 440 450
510 520 530 540 550 560
pF1KE2 GATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTRVSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTRVSA
460 470 480 490 500 510
570 580 590 600 610 620
pF1KE2 SLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTMDDAWKYNGDVEDIKRTPNNVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTMDDAWKYNGDVEDIKRTPNNVV
520 530 540 550 560 570
630 640 650 660 670 680
pF1KE2 STPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPTSPFSSLSQDQAATSKATLSSTSGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPTSPFSSLSQDQAATSKATLSSTSGL
580 590 600 610 620 630
690 700 710 720 730 740
pF1KE2 DLMSESGEGEISPQREVSRSQDQFSDMRISINQTPGKSLDFGFTIKWDIPGIFVASVEAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLMSESGEGEISPQREVSRSQDQFSDMRISINQTPGKSLDFGFTIKWDIPGIFVASVEAG
640 650 660 670 680 690
750 760 770 780 790 800
pF1KE2 SPAEFSQLQVDDEIIAINNTKFSYNDSKEWEEAMAKAQETGHLVMDVRRYGKAGSPETKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPAEFSQLQVDDEIIAINNTKFSYNDSKEWEEAMAKAQETGHLVMDVRRYGKAGSPETKW
700 710 720 730 740 750
810 820 830 840 850 860
pF1KE2 IDATSGIYNSEKSSNLSVTTDFSESLQSSNIESKEINGIHDESNAFESKASESISLKNLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDATSGIYNSEKSSNLSVTTDFSESLQSSNIESKEINGIHDESNAFESKASESISLKNLK
760 770 780 790 800 810
870 880 890 900 910 920
pF1KE2 RRSQFFEQGSSDSVVPDLPVPTISAPSRWVWDQEEERKRQERWQKEQDRLLQEKYQREQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRSQFFEQGSSDSVVPDLPVPTISAPSRWVWDQEEERKRQERWQKEQDRLLQEKYQREQE
820 830 840 850 860 870
930 940 950 960 970 980
pF1KE2 KLREEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLREEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREG
880 890 900 910 920 930
990 1000 1010 1020 1030 1040
pF1KE2 TRAGEEERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRAGEEERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPA
940 950 960 970 980 990
1050 1060 1070 1080 1090 1100
pF1KE2 EEQKRQAEIERETSVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEQKRQAEIERETSVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNK
1000 1010 1020 1030 1040 1050
1110 1120 1130 1140 1150 1160
pF1KE2 NGNNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGNNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASV
1060 1070 1080 1090 1100 1110
1170 1180 1190 1200 1210 1220
pF1KE2 NKEPVSLPGIMRRGESLDNLDSPRSNSWRQPPWLNQPTGFYASSSVQDFSRPPPQLVSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKEPVSLPGIMRRGESLDNLDSPRSNSWRQPPWLNQPTGFYASSSVQDFSRPPPQLVSTS
1120 1130 1140 1150 1160 1170
1230 1240 1250 1260 1270 1280
pF1KE2 NRAYMRNPSSSVPPPSAGSVKTSTTGVATTQSPTPRSHSPSASQSGSQLRNRSVSGKRIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NRAYMRNPSSSVPPPSAGSVKTSTTGVATTQSPTPRSHSPSASQSGSQLRNRSVSGKRIC
1180 1190 1200 1210 1220 1230
1290 1300 1310 1320 1330 1340
pF1KE2 SYCNNILGKGAAMIIESLGLCYHLHCFKCVACECDLGGSSSGAEVRIRNHQLYCNDCYLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYCNNILGKGAAMIIESLGLCYHLHCFKCVACECDLGGSSSGAEVRIRNHQLYCNDCYLR
1240 1250 1260 1270 1280 1290
pF1KE2 FKSGRPTAM
:::::::::
XP_016 FKSGRPTAM
1300
>--
initn: 558 init1: 497 opt: 497 Z-score: 276.5 bits: 63.5 E(88908): 1.2e-08
Smith-Waterman score: 497; 97.3% identity (97.3% similar) in 74 aa overlap (286-359:1-74)
260 270 280 290 300 310
pF1KE2 RSLTSCSSDITLRGGREGFESDTDSEFTFKMQDYNKDDMSYRRISAVEPKTALPFNRFLP
::::::::::::::::::::::::::::::
XP_016 MQDYNKDDMSYRRISAVEPKTALPFNRFLP
10 20 30
320 330 340 350 360 370
pF1KE2 NKSRQPSYVPAPLRKKKPDKHEDNRRSWASPVYTEADGTFSRLFQKIYGENGSKSMSDVS
::::::::::::::::::::::::::::::::::::::::: :
XP_016 NKSRQPSYVPAPLRKKKPDKHEDNRRSWASPVYTEADGTFSSQFLLLQALQTYSDDILSS
40 50 60 70 80 90
380 390 400 410 420 430
pF1KE2 AEDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQ
XP_016 ETHTKIDPTSGPRLITRRKNLSYAPGYRRDDLEMAALDPDLENDDFFVRKTGAFHANPYV
100 110 120 130 140 150
>>XP_016876091 (OMIM: 604362) PREDICTED: LIM domain only (1304 aa)
initn: 6512 init1: 6512 opt: 6522 Z-score: 3425.4 bits: 646.1 E(88908): 4.9e-184
Smith-Waterman score: 6537; 95.3% identity (96.6% similar) in 1059 aa overlap (291-1349:258-1304)
270 280 290 300 310 320
pF1KE2 CSSDITLRGGREGFESDTDSEFTFKMQDYNKDDMSYRRISAVEPKTALPFNRFLPNKSRQ
:::: :.:.. . :..: :
XP_016 AKFLCVLERTCPSKEKSNSCRILVPSYRQKKDDMLTRKIQSWKLGTTVP-----PI----
230 240 250 260 270
330 340 350 360 370 380
pF1KE2 PSYVPAPLRKKKPDKHEDNRRSWASPVYTEADGTFSRLFQKIYGENGSKSMSDVSAEDVQ
:..:.: . . : :. :: . . ::::::::::::::::::::::::
XP_016 -SFTPGPCSEADLKRWEAIRE--ASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQ
280 290 300 310 320 330
390 400 410 420 430 440
pF1KE2 NLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKS
340 350 360 370 380 390
450 460 470 480 490 500
pF1KE2 KRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEK
400 410 420 430 440 450
510 520 530 540 550 560
pF1KE2 GATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTRVSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTRVSA
460 470 480 490 500 510
570 580 590 600 610 620
pF1KE2 SLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTMDDAWKYNGDVEDIKRTPNNVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTMDDAWKYNGDVEDIKRTPNNVV
520 530 540 550 560 570
630 640 650 660 670 680
pF1KE2 STPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPTSPFSSLSQDQAATSKATLSSTSGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPTSPFSSLSQDQAATSKATLSSTSGL
580 590 600 610 620 630
690 700 710 720 730 740
pF1KE2 DLMSESGEGEISPQREVSRSQDQFSDMRISINQTPGKSLDFGFTIKWDIPGIFVASVEAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLMSESGEGEISPQREVSRSQDQFSDMRISINQTPGKSLDFGFTIKWDIPGIFVASVEAG
640 650 660 670 680 690
750 760 770 780 790 800
pF1KE2 SPAEFSQLQVDDEIIAINNTKFSYNDSKEWEEAMAKAQETGHLVMDVRRYGKAGSPETKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPAEFSQLQVDDEIIAINNTKFSYNDSKEWEEAMAKAQETGHLVMDVRRYGKAGSPETKW
700 710 720 730 740 750
810 820 830 840 850 860
pF1KE2 IDATSGIYNSEKSSNLSVTTDFSESLQSSNIESKEINGIHDESNAFESKASESISLKNLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDATSGIYNSEKSSNLSVTTDFSESLQSSNIESKEINGIHDESNAFESKASESISLKNLK
760 770 780 790 800 810
870 880 890 900 910 920
pF1KE2 RRSQFFEQGSSDSVVPDLPVPTISAPSRWVWDQEEERKRQERWQKEQDRLLQEKYQREQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRSQFFEQGSSDSVVPDLPVPTISAPSRWVWDQEEERKRQERWQKEQDRLLQEKYQREQE
820 830 840 850 860 870
930 940 950 960 970 980
pF1KE2 KLREEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLREEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREG
880 890 900 910 920 930
990 1000 1010 1020 1030 1040
pF1KE2 TRAGEEERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRAGEEERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPA
940 950 960 970 980 990
1050 1060 1070 1080 1090 1100
pF1KE2 EEQKRQAEIERETSVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEQKRQAEIERETSVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNK
1000 1010 1020 1030 1040 1050
1110 1120 1130 1140 1150 1160
pF1KE2 NGNNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGNNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASV
1060 1070 1080 1090 1100 1110
1170 1180 1190 1200 1210 1220
pF1KE2 NKEPVSLPGIMRRGESLDNLDSPRSNSWRQPPWLNQPTGFYASSSVQDFSRPPPQLVSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKEPVSLPGIMRRGESLDNLDSPRSNSWRQPPWLNQPTGFYASSSVQDFSRPPPQLVSTS
1120 1130 1140 1150 1160 1170
1230 1240 1250 1260 1270 1280
pF1KE2 NRAYMRNPSSSVPPPSAGSVKTSTTGVATTQSPTPRSHSPSASQSGSQLRNRSVSGKRIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NRAYMRNPSSSVPPPSAGSVKTSTTGVATTQSPTPRSHSPSASQSGSQLRNRSVSGKRIC
1180 1190 1200 1210 1220 1230
1290 1300 1310 1320 1330 1340
pF1KE2 SYCNNILGKGAAMIIESLGLCYHLHCFKCVACECDLGGSSSGAEVRIRNHQLYCNDCYLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYCNNILGKGAAMIIESLGLCYHLHCFKCVACECDLGGSSSGAEVRIRNHQLYCNDCYLR
1240 1250 1260 1270 1280 1290
pF1KE2 FKSGRPTAM
:::::::::
XP_016 FKSGRPTAM
1300
>--
initn: 558 init1: 497 opt: 497 Z-score: 276.5 bits: 63.5 E(88908): 1.2e-08
Smith-Waterman score: 497; 97.3% identity (97.3% similar) in 74 aa overlap (286-359:1-74)
260 270 280 290 300 310
pF1KE2 RSLTSCSSDITLRGGREGFESDTDSEFTFKMQDYNKDDMSYRRISAVEPKTALPFNRFLP
::::::::::::::::::::::::::::::
XP_016 MQDYNKDDMSYRRISAVEPKTALPFNRFLP
10 20 30
320 330 340 350 360 370
pF1KE2 NKSRQPSYVPAPLRKKKPDKHEDNRRSWASPVYTEADGTFSRLFQKIYGENGSKSMSDVS
::::::::::::::::::::::::::::::::::::::::: :
XP_016 NKSRQPSYVPAPLRKKKPDKHEDNRRSWASPVYTEADGTFSSQFLLLQALQTYSDDILSS
40 50 60 70 80 90
380 390 400 410 420 430
pF1KE2 AEDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQ
XP_016 ETHTKIDPTSGPRLITRRKNLSYAPGYRRDDLEMAALDPDLENDDFFVRKTGAFHANPYV
100 110 120 130 140 150
>>NP_001317512 (OMIM: 604362) LIM domain only protein 7 (1398 aa)
initn: 6512 init1: 6512 opt: 6522 Z-score: 3425.0 bits: 646.2 E(88908): 5.1e-184
Smith-Waterman score: 6537; 95.3% identity (96.6% similar) in 1059 aa overlap (291-1349:352-1398)
270 280 290 300 310 320
pF1KE2 CSSDITLRGGREGFESDTDSEFTFKMQDYNKDDMSYRRISAVEPKTALPFNRFLPNKSRQ
:::: :.:.. . :..: :
NP_001 AKFLCVLERTCPSKEKSNSCRILVPSYRQKKDDMLTRKIQSWKLGTTVP-----PI----
330 340 350 360 370
330 340 350 360 370 380
pF1KE2 PSYVPAPLRKKKPDKHEDNRRSWASPVYTEADGTFSRLFQKIYGENGSKSMSDVSAEDVQ
:..:.: . . : :. :: . . ::::::::::::::::::::::::
NP_001 -SFTPGPCSEADLKRWEAIRE--ASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQ
380 390 400 410 420
390 400 410 420 430 440
pF1KE2 NLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKS
430 440 450 460 470 480
450 460 470 480 490 500
pF1KE2 KRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEK
490 500 510 520 530 540
510 520 530 540 550 560
pF1KE2 GATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTRVSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTRVSA
550 560 570 580 590 600
570 580 590 600 610 620
pF1KE2 SLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTMDDAWKYNGDVEDIKRTPNNVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTMDDAWKYNGDVEDIKRTPNNVV
610 620 630 640 650 660
630 640 650 660 670 680
pF1KE2 STPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPTSPFSSLSQDQAATSKATLSSTSGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPTSPFSSLSQDQAATSKATLSSTSGL
670 680 690 700 710 720
690 700 710 720 730 740
pF1KE2 DLMSESGEGEISPQREVSRSQDQFSDMRISINQTPGKSLDFGFTIKWDIPGIFVASVEAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLMSESGEGEISPQREVSRSQDQFSDMRISINQTPGKSLDFGFTIKWDIPGIFVASVEAG
730 740 750 760 770 780
750 760 770 780 790 800
pF1KE2 SPAEFSQLQVDDEIIAINNTKFSYNDSKEWEEAMAKAQETGHLVMDVRRYGKAGSPETKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPAEFSQLQVDDEIIAINNTKFSYNDSKEWEEAMAKAQETGHLVMDVRRYGKAGSPETKW
790 800 810 820 830 840
810 820 830 840 850 860
pF1KE2 IDATSGIYNSEKSSNLSVTTDFSESLQSSNIESKEINGIHDESNAFESKASESISLKNLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IDATSGIYNSEKSSNLSVTTDFSESLQSSNIESKEINGIHDESNAFESKASESISLKNLK
850 860 870 880 890 900
870 880 890 900 910 920
pF1KE2 RRSQFFEQGSSDSVVPDLPVPTISAPSRWVWDQEEERKRQERWQKEQDRLLQEKYQREQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRSQFFEQGSSDSVVPDLPVPTISAPSRWVWDQEEERKRQERWQKEQDRLLQEKYQREQE
910 920 930 940 950 960
930 940 950 960 970 980
pF1KE2 KLREEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLREEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREG
970 980 990 1000 1010 1020
990 1000 1010 1020 1030 1040
pF1KE2 TRAGEEERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TRAGEEERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPA
1030 1040 1050 1060 1070 1080
1050 1060 1070 1080 1090 1100
pF1KE2 EEQKRQAEIERETSVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEQKRQAEIERETSVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNK
1090 1100 1110 1120 1130 1140
1110 1120 1130 1140 1150 1160
pF1KE2 NGNNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NGNNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASV
1150 1160 1170 1180 1190 1200
1170 1180 1190 1200 1210 1220
pF1KE2 NKEPVSLPGIMRRGESLDNLDSPRSNSWRQPPWLNQPTGFYASSSVQDFSRPPPQLVSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NKEPVSLPGIMRRGESLDNLDSPRSNSWRQPPWLNQPTGFYASSSVQDFSRPPPQLVSTS
1210 1220 1230 1240 1250 1260
1230 1240 1250 1260 1270 1280
pF1KE2 NRAYMRNPSSSVPPPSAGSVKTSTTGVATTQSPTPRSHSPSASQSGSQLRNRSVSGKRIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NRAYMRNPSSSVPPPSAGSVKTSTTGVATTQSPTPRSHSPSASQSGSQLRNRSVSGKRIC
1270 1280 1290 1300 1310 1320
1290 1300 1310 1320 1330 1340
pF1KE2 SYCNNILGKGAAMIIESLGLCYHLHCFKCVACECDLGGSSSGAEVRIRNHQLYCNDCYLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SYCNNILGKGAAMIIESLGLCYHLHCFKCVACECDLGGSSSGAEVRIRNHQLYCNDCYLR
1330 1340 1350 1360 1370 1380
pF1KE2 FKSGRPTAM
:::::::::
NP_001 FKSGRPTAM
1390
>--
initn: 562 init1: 508 opt: 508 Z-score: 281.9 bits: 64.6 E(88908): 6.1e-09
Smith-Waterman score: 508; 91.4% identity (95.1% similar) in 81 aa overlap (286-366:1-81)
260 270 280 290 300 310
pF1KE2 RSLTSCSSDITLRGGREGFESDTDSEFTFKMQDYNKDDMSYRRISAVEPKTALPFNRFLP
::::::::::::::::::::::::::::::
NP_001 MQDYNKDDMSYRRISAVEPKTALPFNRFLP
10 20 30
320 330 340 350 360 370
pF1KE2 NKSRQPSYVPAPLRKKKPDKHEDNRRSWASPVYTEADGTFSRLFQKIYGENGSKSMSDVS
::::::::::::::::::::::::::::::::::::::::: ..:.: :
NP_001 NKSRQPSYVPAPLRKKKPDKHEDNRRSWASPVYTEADGTFSSNQRRIWGTNVENWPTVQG
40 50 60 70 80 90
380 390 400 410 420 430
pF1KE2 AEDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQ
NP_001 TSKSSCYLEEEKAKTRSIPNIVKDDLYVRKLSPVMPNPGNAFDQFLPKCWTPEDVNWKRI
100 110 120 130 140 150
>>XP_011533384 (OMIM: 604362) PREDICTED: LIM domain only (1466 aa)
initn: 6512 init1: 6512 opt: 6522 Z-score: 3424.7 bits: 646.2 E(88908): 5.3e-184
Smith-Waterman score: 6537; 95.3% identity (96.6% similar) in 1059 aa overlap (291-1349:420-1466)
270 280 290 300 310 320
pF1KE2 CSSDITLRGGREGFESDTDSEFTFKMQDYNKDDMSYRRISAVEPKTALPFNRFLPNKSRQ
:::: :.:.. . :..: :
XP_011 AKFLCVLERTCPSKEKSNSCRILVPSYRQKKDDMLTRKIQSWKLGTTVP-----PI----
390 400 410 420 430 440
330 340 350 360 370 380
pF1KE2 PSYVPAPLRKKKPDKHEDNRRSWASPVYTEADGTFSRLFQKIYGENGSKSMSDVSAEDVQ
:..:.: . . : :. :: . . ::::::::::::::::::::::::
XP_011 -SFTPGPCSEADLKRWEAIRE--ASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQ
450 460 470 480 490
390 400 410 420 430 440
pF1KE2 NLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKS
500 510 520 530 540 550
450 460 470 480 490 500
pF1KE2 KRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEK
560 570 580 590 600 610
510 520 530 540 550 560
pF1KE2 GATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTRVSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTRVSA
620 630 640 650 660 670
570 580 590 600 610 620
pF1KE2 SLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTMDDAWKYNGDVEDIKRTPNNVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTMDDAWKYNGDVEDIKRTPNNVV
680 690 700 710 720 730
630 640 650 660 670 680
pF1KE2 STPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPTSPFSSLSQDQAATSKATLSSTSGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPTSPFSSLSQDQAATSKATLSSTSGL
740 750 760 770 780 790
690 700 710 720 730 740
pF1KE2 DLMSESGEGEISPQREVSRSQDQFSDMRISINQTPGKSLDFGFTIKWDIPGIFVASVEAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLMSESGEGEISPQREVSRSQDQFSDMRISINQTPGKSLDFGFTIKWDIPGIFVASVEAG
800 810 820 830 840 850
750 760 770 780 790 800
pF1KE2 SPAEFSQLQVDDEIIAINNTKFSYNDSKEWEEAMAKAQETGHLVMDVRRYGKAGSPETKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPAEFSQLQVDDEIIAINNTKFSYNDSKEWEEAMAKAQETGHLVMDVRRYGKAGSPETKW
860 870 880 890 900 910
810 820 830 840 850 860
pF1KE2 IDATSGIYNSEKSSNLSVTTDFSESLQSSNIESKEINGIHDESNAFESKASESISLKNLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IDATSGIYNSEKSSNLSVTTDFSESLQSSNIESKEINGIHDESNAFESKASESISLKNLK
920 930 940 950 960 970
870 880 890 900 910 920
pF1KE2 RRSQFFEQGSSDSVVPDLPVPTISAPSRWVWDQEEERKRQERWQKEQDRLLQEKYQREQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRSQFFEQGSSDSVVPDLPVPTISAPSRWVWDQEEERKRQERWQKEQDRLLQEKYQREQE
980 990 1000 1010 1020 1030
930 940 950 960 970 980
pF1KE2 KLREEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLREEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREG
1040 1050 1060 1070 1080 1090
990 1000 1010 1020 1030 1040
pF1KE2 TRAGEEERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRAGEEERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPA
1100 1110 1120 1130 1140 1150
1050 1060 1070 1080 1090 1100
pF1KE2 EEQKRQAEIERETSVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEQKRQAEIERETSVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNK
1160 1170 1180 1190 1200 1210
1110 1120 1130 1140 1150 1160
pF1KE2 NGNNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGNNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASV
1220 1230 1240 1250 1260 1270
1170 1180 1190 1200 1210 1220
pF1KE2 NKEPVSLPGIMRRGESLDNLDSPRSNSWRQPPWLNQPTGFYASSSVQDFSRPPPQLVSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NKEPVSLPGIMRRGESLDNLDSPRSNSWRQPPWLNQPTGFYASSSVQDFSRPPPQLVSTS
1280 1290 1300 1310 1320 1330
1230 1240 1250 1260 1270 1280
pF1KE2 NRAYMRNPSSSVPPPSAGSVKTSTTGVATTQSPTPRSHSPSASQSGSQLRNRSVSGKRIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NRAYMRNPSSSVPPPSAGSVKTSTTGVATTQSPTPRSHSPSASQSGSQLRNRSVSGKRIC
1340 1350 1360 1370 1380 1390
1290 1300 1310 1320 1330 1340
pF1KE2 SYCNNILGKGAAMIIESLGLCYHLHCFKCVACECDLGGSSSGAEVRIRNHQLYCNDCYLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SYCNNILGKGAAMIIESLGLCYHLHCFKCVACECDLGGSSSGAEVRIRNHQLYCNDCYLR
1400 1410 1420 1430 1440 1450
pF1KE2 FKSGRPTAM
:::::::::
XP_011 FKSGRPTAM
1460
>--
initn: 546 init1: 492 opt: 508 Z-score: 281.6 bits: 64.6 E(88908): 6.3e-09
Smith-Waterman score: 508; 91.4% identity (95.1% similar) in 81 aa overlap (286-366:1-81)
260 270 280 290 300 310
pF1KE2 RSLTSCSSDITLRGGREGFESDTDSEFTFKMQDYNKDDMSYRRISAVEPKTALPFNRFLP
::::::::::::::::::::::::::::::
XP_011 MQDYNKDDMSYRRISAVEPKTALPFNRFLP
10 20 30
320 330 340 350 360 370
pF1KE2 NKSRQPSYVPAPLRKKKPDKHEDNRRSWASPVYTEADGTFSRLFQKIYGENGSKSMSDVS
::::::::::::::::::::::::::::::::::::::::: ..:.: :
XP_011 NKSRQPSYVPAPLRKKKPDKHEDNRRSWASPVYTEADGTFSSNQRRIWGTNVENWPTVQG
40 50 60 70 80 90
380 390 400 410 420 430
pF1KE2 AEDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQ
XP_011 TSKSSCYLEEEKAKTRSIPNIVKDDLYVRKLSPVMPNPGNAFDQFLPKCWTPEDVNWKRI
100 110 120 130 140 150
>>NP_001293009 (OMIM: 604362) LIM domain only protein 7 (1631 aa)
initn: 6512 init1: 6512 opt: 6522 Z-score: 3424.1 bits: 646.2 E(88908): 5.8e-184
Smith-Waterman score: 6537; 95.3% identity (96.6% similar) in 1059 aa overlap (291-1349:585-1631)
270 280 290 300 310 320
pF1KE2 CSSDITLRGGREGFESDTDSEFTFKMQDYNKDDMSYRRISAVEPKTALPFNRFLPNKSRQ
:::: :.:.. . :..: :
NP_001 AKFLCVLERTCPSKEKSNSCRILVPSYRQKKDDMLTRKIQSWKLGTTVP-----PI----
560 570 580 590 600
330 340 350 360 370 380
pF1KE2 PSYVPAPLRKKKPDKHEDNRRSWASPVYTEADGTFSRLFQKIYGENGSKSMSDVSAEDVQ
:..:.: . . : :. :: . . ::::::::::::::::::::::::
NP_001 -SFTPGPCSEADLKRWEAIRE--ASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQ
610 620 630 640 650 660
390 400 410 420 430 440
pF1KE2 NLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKS
670 680 690 700 710 720
450 460 470 480 490 500
pF1KE2 KRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEK
730 740 750 760 770 780
510 520 530 540 550 560
pF1KE2 GATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTRVSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTRVSA
790 800 810 820 830 840
570 580 590 600 610 620
pF1KE2 SLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTMDDAWKYNGDVEDIKRTPNNVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTMDDAWKYNGDVEDIKRTPNNVV
850 860 870 880 890 900
630 640 650 660 670 680
pF1KE2 STPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPTSPFSSLSQDQAATSKATLSSTSGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPTSPFSSLSQDQAATSKATLSSTSGL
910 920 930 940 950 960
690 700 710 720 730 740
pF1KE2 DLMSESGEGEISPQREVSRSQDQFSDMRISINQTPGKSLDFGFTIKWDIPGIFVASVEAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLMSESGEGEISPQREVSRSQDQFSDMRISINQTPGKSLDFGFTIKWDIPGIFVASVEAG
970 980 990 1000 1010 1020
750 760 770 780 790 800
pF1KE2 SPAEFSQLQVDDEIIAINNTKFSYNDSKEWEEAMAKAQETGHLVMDVRRYGKAGSPETKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPAEFSQLQVDDEIIAINNTKFSYNDSKEWEEAMAKAQETGHLVMDVRRYGKAGSPETKW
1030 1040 1050 1060 1070 1080
810 820 830 840 850 860
pF1KE2 IDATSGIYNSEKSSNLSVTTDFSESLQSSNIESKEINGIHDESNAFESKASESISLKNLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IDATSGIYNSEKSSNLSVTTDFSESLQSSNIESKEINGIHDESNAFESKASESISLKNLK
1090 1100 1110 1120 1130 1140
870 880 890 900 910 920
pF1KE2 RRSQFFEQGSSDSVVPDLPVPTISAPSRWVWDQEEERKRQERWQKEQDRLLQEKYQREQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRSQFFEQGSSDSVVPDLPVPTISAPSRWVWDQEEERKRQERWQKEQDRLLQEKYQREQE
1150 1160 1170 1180 1190 1200
930 940 950 960 970 980
pF1KE2 KLREEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLREEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREG
1210 1220 1230 1240 1250 1260
990 1000 1010 1020 1030 1040
pF1KE2 TRAGEEERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TRAGEEERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPA
1270 1280 1290 1300 1310 1320
1050 1060 1070 1080 1090 1100
pF1KE2 EEQKRQAEIERETSVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEQKRQAEIERETSVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNK
1330 1340 1350 1360 1370 1380
1110 1120 1130 1140 1150 1160
pF1KE2 NGNNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NGNNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASV
1390 1400 1410 1420 1430 1440
1170 1180 1190 1200 1210 1220
pF1KE2 NKEPVSLPGIMRRGESLDNLDSPRSNSWRQPPWLNQPTGFYASSSVQDFSRPPPQLVSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NKEPVSLPGIMRRGESLDNLDSPRSNSWRQPPWLNQPTGFYASSSVQDFSRPPPQLVSTS
1450 1460 1470 1480 1490 1500
1230 1240 1250 1260 1270 1280
pF1KE2 NRAYMRNPSSSVPPPSAGSVKTSTTGVATTQSPTPRSHSPSASQSGSQLRNRSVSGKRIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NRAYMRNPSSSVPPPSAGSVKTSTTGVATTQSPTPRSHSPSASQSGSQLRNRSVSGKRIC
1510 1520 1530 1540 1550 1560
1290 1300 1310 1320 1330 1340
pF1KE2 SYCNNILGKGAAMIIESLGLCYHLHCFKCVACECDLGGSSSGAEVRIRNHQLYCNDCYLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SYCNNILGKGAAMIIESLGLCYHLHCFKCVACECDLGGSSSGAEVRIRNHQLYCNDCYLR
1570 1580 1590 1600 1610 1620
pF1KE2 FKSGRPTAM
:::::::::
NP_001 FKSGRPTAM
1630
>--
initn: 1942 init1: 1906 opt: 1906 Z-score: 1011.6 bits: 199.8 E(88908): 1.4e-49
Smith-Waterman score: 1906; 96.9% identity (98.6% similar) in 293 aa overlap (74-366:22-314)
50 60 70 80 90 100
pF1KE2 CVGWLYLRDRVCSKKDIILRTEQNSGRTILIKAVTEKNFETKDFRASLENGVLLCDLINK
..::::::::::::::::::::::::::::
NP_001 MEGLEEAEANCSVAFAEAQRWVEAVTEKNFETKDFRASLENGVLLCDLINK
10 20 30 40 50
110 120 130 140 150 160
pF1KE2 LKPGVIKKINRLSTPIAGLDNINVFLKACEQIGLKEAQLFHPGDLQDLSNRVTVKQEETD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKPGVIKKINRLSTPIAGLDNINVFLKACEQIGLKEAQLFHPGDLQDLSNRVTVKQEETD
60 70 80 90 100 110
170 180 190 200 210 220
pF1KE2 RRVKNVLITLYWLGRKAQSNPYYNGPHLNLKAFENLLGQALTKALEDSSFLKRSGRDSGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRVKNVLITLYWLGRKAQSNPYYNGPHLNLKAFENLLGQALTKALEDSSFLKRSGRDSGY
120 130 140 150 160 170
230 240 250 260 270 280
pF1KE2 GDIWCPERGEFLAPPRHHKREDSFESLDSLGSRSLTSCSSDITLRGGREGFESDTDSEFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDIWCPERGEFLAPPRHHKREDSFESLDSLGSRSLTSCSSDITLRGGREGFESDTDSEFT
180 190 200 210 220 230
290 300 310 320 330 340
pF1KE2 FKMQDYNKDDMSYRRISAVEPKTALPFNRFLPNKSRQPSYVPAPLRKKKPDKHEDNRRSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FKMQDYNKDDMSYRRISAVEPKTALPFNRFLPNKSRQPSYVPAPLRKKKPDKHEDNRRSW
240 250 260 270 280 290
350 360 370 380 390 400
pF1KE2 ASPVYTEADGTFSRLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLKEQDQK
::::::::::::: ..:.: :
NP_001 ASPVYTEADGTFSSNQRRIWGTNVENWPTVQGTSKSSCYLEEEKAKTRSIPNIVKDDLYV
300 310 320 330 340 350
>>XP_016876076 (OMIM: 604362) PREDICTED: LIM domain only (1320 aa)
initn: 7032 init1: 6469 opt: 6479 Z-score: 3402.9 bits: 642.0 E(88908): 8.8e-183
Smith-Waterman score: 6494; 95.1% identity (96.4% similar) in 1055 aa overlap (291-1345:258-1300)
270 280 290 300 310 320
pF1KE2 CSSDITLRGGREGFESDTDSEFTFKMQDYNKDDMSYRRISAVEPKTALPFNRFLPNKSRQ
:::: :.:.. . :..: :
XP_016 AKFLCVLERTCPSKEKSNSCRILVPSYRQKKDDMLTRKIQSWKLGTTVP-----PI----
230 240 250 260 270
330 340 350 360 370 380
pF1KE2 PSYVPAPLRKKKPDKHEDNRRSWASPVYTEADGTFSRLFQKIYGENGSKSMSDVSAEDVQ
:..:.: . . : :. :: . . ::::::::::::::::::::::::
XP_016 -SFTPGPCSEADLKRWEAIRE--ASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQ
280 290 300 310 320 330
390 400 410 420 430 440
pF1KE2 NLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKS
340 350 360 370 380 390
450 460 470 480 490 500
pF1KE2 KRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEK
400 410 420 430 440 450
510 520 530 540 550 560
pF1KE2 GATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTRVSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTRVSA
460 470 480 490 500 510
570 580 590 600 610 620
pF1KE2 SLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTMDDAWKYNGDVEDIKRTPNNVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTMDDAWKYNGDVEDIKRTPNNVV
520 530 540 550 560 570
630 640 650 660 670 680
pF1KE2 STPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPTSPFSSLSQDQAATSKATLSSTSGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPTSPFSSLSQDQAATSKATLSSTSGL
580 590 600 610 620 630
690 700 710 720 730 740
pF1KE2 DLMSESGEGEISPQREVSRSQDQFSDMRISINQTPGKSLDFGFTIKWDIPGIFVASVEAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLMSESGEGEISPQREVSRSQDQFSDMRISINQTPGKSLDFGFTIKWDIPGIFVASVEAG
640 650 660 670 680 690
750 760 770 780 790 800
pF1KE2 SPAEFSQLQVDDEIIAINNTKFSYNDSKEWEEAMAKAQETGHLVMDVRRYGKAGSPETKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPAEFSQLQVDDEIIAINNTKFSYNDSKEWEEAMAKAQETGHLVMDVRRYGKAGSPETKW
700 710 720 730 740 750
810 820 830 840 850 860
pF1KE2 IDATSGIYNSEKSSNLSVTTDFSESLQSSNIESKEINGIHDESNAFESKASESISLKNLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDATSGIYNSEKSSNLSVTTDFSESLQSSNIESKEINGIHDESNAFESKASESISLKNLK
760 770 780 790 800 810
870 880 890 900 910 920
pF1KE2 RRSQFFEQGSSDSVVPDLPVPTISAPSRWVWDQEEERKRQERWQKEQDRLLQEKYQREQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRSQFFEQGSSDSVVPDLPVPTISAPSRWVWDQEEERKRQERWQKEQDRLLQEKYQREQE
820 830 840 850 860 870
930 940 950 960 970 980
pF1KE2 KLREEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLREEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREG
880 890 900 910 920 930
990 1000 1010 1020 1030 1040
pF1KE2 TRAGEEERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRAGEEERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPA
940 950 960 970 980 990
1050 1060 1070 1080 1090 1100
pF1KE2 EEQKRQAEIERETSVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEQKRQAEIERETSVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNK
1000 1010 1020 1030 1040 1050
1110 1120 1130 1140 1150 1160
pF1KE2 NGNNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGNNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASV
1060 1070 1080 1090 1100 1110
1170 1180 1190 1200 1210 1220
pF1KE2 NKEPVSLPGIMRRGESLDNLDSPRSNSWRQPPWLNQPTGFYASSSVQDFSRPPPQLVSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKEPVSLPGIMRRGESLDNLDSPRSNSWRQPPWLNQPTGFYASSSVQDFSRPPPQLVSTS
1120 1130 1140 1150 1160 1170
1230 1240 1250 1260 1270 1280
pF1KE2 NRAYMRNPSSSVPPPSAGSVKTSTTGVATTQSPTPRSHSPSASQSGSQLRNRSVSGKRIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NRAYMRNPSSSVPPPSAGSVKTSTTGVATTQSPTPRSHSPSASQSGSQLRNRSVSGKRIC
1180 1190 1200 1210 1220 1230
1290 1300 1310 1320 1330 1340
pF1KE2 SYCNNILGKGAAMIIESLGLCYHLHCFKCVACECDLGGSSSGAEVRIRNHQLYCNDCYLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYCNNILGKGAAMIIESLGLCYHLHCFKCVACECDLGGSSSGAEVRIRNHQLYCNDCYLR
1240 1250 1260 1270 1280 1290
pF1KE2 FKSGRPTAM
:: :
XP_016 FKCKRANQRENFLPFKEATGSHAFP
1300 1310 1320
>--
initn: 558 init1: 497 opt: 497 Z-score: 276.5 bits: 63.5 E(88908): 1.2e-08
Smith-Waterman score: 497; 97.3% identity (97.3% similar) in 74 aa overlap (286-359:1-74)
260 270 280 290 300 310
pF1KE2 RSLTSCSSDITLRGGREGFESDTDSEFTFKMQDYNKDDMSYRRISAVEPKTALPFNRFLP
::::::::::::::::::::::::::::::
XP_016 MQDYNKDDMSYRRISAVEPKTALPFNRFLP
10 20 30
320 330 340 350 360 370
pF1KE2 NKSRQPSYVPAPLRKKKPDKHEDNRRSWASPVYTEADGTFSRLFQKIYGENGSKSMSDVS
::::::::::::::::::::::::::::::::::::::::: :
XP_016 NKSRQPSYVPAPLRKKKPDKHEDNRRSWASPVYTEADGTFSSQFLLLQALQTYSDDILSS
40 50 60 70 80 90
380 390 400 410 420 430
pF1KE2 AEDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQ
XP_016 ETHTKIDPTSGPRLITRRKNLSYAPGYRRDDLEMAALDPDLENDDFFVRKTGAFHANPYV
100 110 120 130 140 150
>>XP_016876068 (OMIM: 604362) PREDICTED: LIM domain only (1482 aa)
initn: 7043 init1: 6469 opt: 6479 Z-score: 3402.2 bits: 642.0 E(88908): 9.6e-183
Smith-Waterman score: 6494; 95.1% identity (96.4% similar) in 1055 aa overlap (291-1345:420-1462)
270 280 290 300 310 320
pF1KE2 CSSDITLRGGREGFESDTDSEFTFKMQDYNKDDMSYRRISAVEPKTALPFNRFLPNKSRQ
:::: :.:.. . :..: :
XP_016 AKFLCVLERTCPSKEKSNSCRILVPSYRQKKDDMLTRKIQSWKLGTTVP-----PI----
390 400 410 420 430 440
330 340 350 360 370 380
pF1KE2 PSYVPAPLRKKKPDKHEDNRRSWASPVYTEADGTFSRLFQKIYGENGSKSMSDVSAEDVQ
:..:.: . . : :. :: . . ::::::::::::::::::::::::
XP_016 -SFTPGPCSEADLKRWEAIRE--ASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQ
450 460 470 480 490
390 400 410 420 430 440
pF1KE2 NLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKS
500 510 520 530 540 550
450 460 470 480 490 500
pF1KE2 KRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEK
560 570 580 590 600 610
510 520 530 540 550 560
pF1KE2 GATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTRVSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTRVSA
620 630 640 650 660 670
570 580 590 600 610 620
pF1KE2 SLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTMDDAWKYNGDVEDIKRTPNNVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTMDDAWKYNGDVEDIKRTPNNVV
680 690 700 710 720 730
630 640 650 660 670 680
pF1KE2 STPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPTSPFSSLSQDQAATSKATLSSTSGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPTSPFSSLSQDQAATSKATLSSTSGL
740 750 760 770 780 790
690 700 710 720 730 740
pF1KE2 DLMSESGEGEISPQREVSRSQDQFSDMRISINQTPGKSLDFGFTIKWDIPGIFVASVEAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLMSESGEGEISPQREVSRSQDQFSDMRISINQTPGKSLDFGFTIKWDIPGIFVASVEAG
800 810 820 830 840 850
750 760 770 780 790 800
pF1KE2 SPAEFSQLQVDDEIIAINNTKFSYNDSKEWEEAMAKAQETGHLVMDVRRYGKAGSPETKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPAEFSQLQVDDEIIAINNTKFSYNDSKEWEEAMAKAQETGHLVMDVRRYGKAGSPETKW
860 870 880 890 900 910
810 820 830 840 850 860
pF1KE2 IDATSGIYNSEKSSNLSVTTDFSESLQSSNIESKEINGIHDESNAFESKASESISLKNLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDATSGIYNSEKSSNLSVTTDFSESLQSSNIESKEINGIHDESNAFESKASESISLKNLK
920 930 940 950 960 970
870 880 890 900 910 920
pF1KE2 RRSQFFEQGSSDSVVPDLPVPTISAPSRWVWDQEEERKRQERWQKEQDRLLQEKYQREQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRSQFFEQGSSDSVVPDLPVPTISAPSRWVWDQEEERKRQERWQKEQDRLLQEKYQREQE
980 990 1000 1010 1020 1030
930 940 950 960 970 980
pF1KE2 KLREEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLREEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREG
1040 1050 1060 1070 1080 1090
990 1000 1010 1020 1030 1040
pF1KE2 TRAGEEERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRAGEEERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPA
1100 1110 1120 1130 1140 1150
1050 1060 1070 1080 1090 1100
pF1KE2 EEQKRQAEIERETSVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEQKRQAEIERETSVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNK
1160 1170 1180 1190 1200 1210
1110 1120 1130 1140 1150 1160
pF1KE2 NGNNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGNNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASV
1220 1230 1240 1250 1260 1270
1170 1180 1190 1200 1210 1220
pF1KE2 NKEPVSLPGIMRRGESLDNLDSPRSNSWRQPPWLNQPTGFYASSSVQDFSRPPPQLVSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKEPVSLPGIMRRGESLDNLDSPRSNSWRQPPWLNQPTGFYASSSVQDFSRPPPQLVSTS
1280 1290 1300 1310 1320 1330
1230 1240 1250 1260 1270 1280
pF1KE2 NRAYMRNPSSSVPPPSAGSVKTSTTGVATTQSPTPRSHSPSASQSGSQLRNRSVSGKRIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NRAYMRNPSSSVPPPSAGSVKTSTTGVATTQSPTPRSHSPSASQSGSQLRNRSVSGKRIC
1340 1350 1360 1370 1380 1390
1290 1300 1310 1320 1330 1340
pF1KE2 SYCNNILGKGAAMIIESLGLCYHLHCFKCVACECDLGGSSSGAEVRIRNHQLYCNDCYLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYCNNILGKGAAMIIESLGLCYHLHCFKCVACECDLGGSSSGAEVRIRNHQLYCNDCYLR
1400 1410 1420 1430 1440 1450
pF1KE2 FKSGRPTAM
:: :
XP_016 FKCKRANQRENFLPFKEATGSHAFP
1460 1470 1480
>--
initn: 546 init1: 492 opt: 508 Z-score: 281.5 bits: 64.6 E(88908): 6.4e-09
Smith-Waterman score: 508; 91.4% identity (95.1% similar) in 81 aa overlap (286-366:1-81)
260 270 280 290 300 310
pF1KE2 RSLTSCSSDITLRGGREGFESDTDSEFTFKMQDYNKDDMSYRRISAVEPKTALPFNRFLP
::::::::::::::::::::::::::::::
XP_016 MQDYNKDDMSYRRISAVEPKTALPFNRFLP
10 20 30
320 330 340 350 360 370
pF1KE2 NKSRQPSYVPAPLRKKKPDKHEDNRRSWASPVYTEADGTFSRLFQKIYGENGSKSMSDVS
::::::::::::::::::::::::::::::::::::::::: ..:.: :
XP_016 NKSRQPSYVPAPLRKKKPDKHEDNRRSWASPVYTEADGTFSSNQRRIWGTNVENWPTVQG
40 50 60 70 80 90
380 390 400 410 420 430
pF1KE2 AEDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQ
XP_016 TSKSSCYLEEEKAKTRSIPNIVKDDLYVRKLSPVMPNPGNAFDQFLPKCWTPEDVNWKRI
100 110 120 130 140 150
>>XP_016876067 (OMIM: 604362) PREDICTED: LIM domain only (1490 aa)
initn: 6854 init1: 3207 opt: 6037 Z-score: 3171.1 bits: 599.3 E(88908): 7.1e-170
Smith-Waterman score: 6267; 90.9% identity (92.2% similar) in 1082 aa overlap (291-1345:420-1470)
270 280 290 300 310 320
pF1KE2 CSSDITLRGGREGFESDTDSEFTFKMQDYNKDDMSYRRISAVEPKTALPFNRFLPNKSRQ
:::: :.:.. . :..: :
XP_016 AKFLCVLERTCPSKEKSNSCRILVPSYRQKKDDMLTRKIQSWKLGTTVP-----PI----
390 400 410 420 430 440
330 340 350 360 370 380
pF1KE2 PSYVPAPLRKKKPDKHEDNRRSWASPVYTEADGTFSRLFQKIYGENGSKSMSDVSAEDVQ
:..:.: . . : :. :: . . ::::::::::::::::::::::::
XP_016 -SFTPGPCSEADLKRWEAIRE--ASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQ
450 460 470 480 490
390 400 410 420 430 440
pF1KE2 NLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKS
500 510 520 530 540 550
450 460 470 480 490 500
pF1KE2 KRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEK
560 570 580 590 600 610
510 520 530 540 550 560
pF1KE2 GATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTRVSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTRVSA
620 630 640 650 660 670
570 580 590 600 610 620
pF1KE2 SLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTMDDAWKYNGDVEDIKRTPNNVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTMDDAWKYNGDVEDIKRTPNNVV
680 690 700 710 720 730
630 640 650 660 670 680
pF1KE2 STPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPTSPFSSLSQDQAATSKATLSSTSGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPTSPFSSLSQDQAATSKATLSSTSGL
740 750 760 770 780 790
690 700 710 720 730 740
pF1KE2 DLMSESGEGEISPQREVSRSQDQFSDMRISINQTPGKSLDFGFTIKWDIPGIFVASVEAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLMSESGEGEISPQREVSRSQDQFSDMRISINQTPGKSLDFGFTIKWDIPGIFVASVEAG
800 810 820 830 840 850
750 760 770 780 790
pF1KE2 SPAEFSQLQVDDEIIAINNTKFSYNDSKEWEEAMAKAQETGHLVMDVRRYGKA-------
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPAEFSQLQVDDEIIAINNTKFSYNDSKEWEEAMAKAQETGHLVMDVRRYGKADWGKDQP
860 870 880 890 900 910
800 810 820 830
pF1KE2 --------------------GSPETKWIDATSGIYNSEKSSNLSVTTDFSESLQSSNIES
::::::::::::::::::::::::::::::::::::::::
XP_016 SLPFIRHKTLNLTSMATKIIGSPETKWIDATSGIYNSEKSSNLSVTTDFSESLQSSNIES
920 930 940 950 960 970
840 850 860 870 880 890
pF1KE2 KEINGIHDESNAFESKASESISLKNLKRRSQFFEQGSSDSVVPDLPVPTISAPSRWVWDQ
:::::::::::::::: :::::::::::::::::::::::::
XP_016 KEINGIHDESNAFESK-------------------GSSDSVVPDLPVPTISAPSRWVWDQ
980 990 1000 1010
900 910 920 930 940 950
pF1KE2 EEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNSM
1020 1030 1040 1050 1060 1070
960 970 980 990 1000 1010
pF1KE2 SLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIERE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIERE
1080 1090 1100 1110 1120 1130
1020 1030 1040 1050 1060 1070
pF1KE2 RKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIPKTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIPKTE
1140 1150 1160 1170 1180 1190
1080 1090 1100 1110 1120 1130
pF1KE2 EASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSGAELER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSGAELER
1200 1210 1220 1230 1240 1250
1140 1150 1160 1170 1180 1190
pF1KE2 QQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGESLDNLDSPRSNSWRQPPW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGESLDNLDSPRSNSWRQPPW
1260 1270 1280 1290 1300 1310
1200 1210 1220 1230 1240 1250
pF1KE2 LNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNPSSSVPPPSAGSVKTSTTGVATTQSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNPSSSVPPPSAGSVKTSTTGVATTQSP
1320 1330 1340 1350 1360 1370
1260 1270 1280 1290 1300 1310
pF1KE2 TPRSHSPSASQSGSQLRNRSVSGKRICSYCNNILGKGAAMIIESLGLCYHLHCFKCVACE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPRSHSPSASQSGSQLRNRSVSGKRICSYCNNILGKGAAMIIESLGLCYHLHCFKCVACE
1380 1390 1400 1410 1420 1430
1320 1330 1340
pF1KE2 CDLGGSSSGAEVRIRNHQLYCNDCYLRFKSGRPTAM
::::::::::::::::::::::::::::: :
XP_016 CDLGGSSSGAEVRIRNHQLYCNDCYLRFKCKRANQRENFLPFKEATGSHAFP
1440 1450 1460 1470 1480 1490
>--
initn: 546 init1: 492 opt: 508 Z-score: 281.5 bits: 64.6 E(88908): 6.4e-09
Smith-Waterman score: 508; 91.4% identity (95.1% similar) in 81 aa overlap (286-366:1-81)
260 270 280 290 300 310
pF1KE2 RSLTSCSSDITLRGGREGFESDTDSEFTFKMQDYNKDDMSYRRISAVEPKTALPFNRFLP
::::::::::::::::::::::::::::::
XP_016 MQDYNKDDMSYRRISAVEPKTALPFNRFLP
10 20 30
320 330 340 350 360 370
pF1KE2 NKSRQPSYVPAPLRKKKPDKHEDNRRSWASPVYTEADGTFSRLFQKIYGENGSKSMSDVS
::::::::::::::::::::::::::::::::::::::::: ..:.: :
XP_016 NKSRQPSYVPAPLRKKKPDKHEDNRRSWASPVYTEADGTFSSNQRRIWGTNVENWPTVQG
40 50 60 70 80 90
380 390 400 410 420 430
pF1KE2 AEDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQ
XP_016 TSKSSCYLEEEKAKTRSIPNIVKDDLYVRKLSPVMPNPGNAFDQFLPKCWTPEDVNWKRI
100 110 120 130 140 150
>>XP_016876092 (OMIM: 604362) PREDICTED: LIM domain only (1291 aa)
initn: 5949 init1: 5949 opt: 5959 Z-score: 3131.2 bits: 591.7 E(88908): 1.2e-167
Smith-Waterman score: 5974; 94.9% identity (96.3% similar) in 981 aa overlap (291-1271:258-1226)
270 280 290 300 310 320
pF1KE2 CSSDITLRGGREGFESDTDSEFTFKMQDYNKDDMSYRRISAVEPKTALPFNRFLPNKSRQ
:::: :.:.. . :..: :
XP_016 AKFLCVLERTCPSKEKSNSCRILVPSYRQKKDDMLTRKIQSWKLGTTVP-----P-----
230 240 250 260 270
330 340 350 360 370 380
pF1KE2 PSYVPAPLRKKKPDKHEDNRRSWASPVYTEADGTFSRLFQKIYGENGSKSMSDVSAEDVQ
:..:.: . . : :. :: . . ::::::::::::::::::::::::
XP_016 ISFTPGPCSEADLKRWEAIRE--ASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQ
280 290 300 310 320 330
390 400 410 420 430 440
pF1KE2 NLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKS
340 350 360 370 380 390
450 460 470 480 490 500
pF1KE2 KRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEK
400 410 420 430 440 450
510 520 530 540 550 560
pF1KE2 GATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTRVSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTRVSA
460 470 480 490 500 510
570 580 590 600 610 620
pF1KE2 SLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTMDDAWKYNGDVEDIKRTPNNVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTMDDAWKYNGDVEDIKRTPNNVV
520 530 540 550 560 570
630 640 650 660 670 680
pF1KE2 STPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPTSPFSSLSQDQAATSKATLSSTSGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPTSPFSSLSQDQAATSKATLSSTSGL
580 590 600 610 620 630
690 700 710 720 730 740
pF1KE2 DLMSESGEGEISPQREVSRSQDQFSDMRISINQTPGKSLDFGFTIKWDIPGIFVASVEAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLMSESGEGEISPQREVSRSQDQFSDMRISINQTPGKSLDFGFTIKWDIPGIFVASVEAG
640 650 660 670 680 690
750 760 770 780 790 800
pF1KE2 SPAEFSQLQVDDEIIAINNTKFSYNDSKEWEEAMAKAQETGHLVMDVRRYGKAGSPETKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPAEFSQLQVDDEIIAINNTKFSYNDSKEWEEAMAKAQETGHLVMDVRRYGKAGSPETKW
700 710 720 730 740 750
810 820 830 840 850 860
pF1KE2 IDATSGIYNSEKSSNLSVTTDFSESLQSSNIESKEINGIHDESNAFESKASESISLKNLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDATSGIYNSEKSSNLSVTTDFSESLQSSNIESKEINGIHDESNAFESKASESISLKNLK
760 770 780 790 800 810
870 880 890 900 910 920
pF1KE2 RRSQFFEQGSSDSVVPDLPVPTISAPSRWVWDQEEERKRQERWQKEQDRLLQEKYQREQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRSQFFEQGSSDSVVPDLPVPTISAPSRWVWDQEEERKRQERWQKEQDRLLQEKYQREQE
820 830 840 850 860 870
930 940 950 960 970 980
pF1KE2 KLREEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLREEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREG
880 890 900 910 920 930
990 1000 1010 1020 1030 1040
pF1KE2 TRAGEEERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRAGEEERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPA
940 950 960 970 980 990
1050 1060 1070 1080 1090 1100
pF1KE2 EEQKRQAEIERETSVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEQKRQAEIERETSVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNK
1000 1010 1020 1030 1040 1050
1110 1120 1130 1140 1150 1160
pF1KE2 NGNNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGNNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASV
1060 1070 1080 1090 1100 1110
1170 1180 1190 1200 1210 1220
pF1KE2 NKEPVSLPGIMRRGESLDNLDSPRSNSWRQPPWLNQPTGFYASSSVQDFSRPPPQLVSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKEPVSLPGIMRRGESLDNLDSPRSNSWRQPPWLNQPTGFYASSSVQDFSRPPPQLVSTS
1120 1130 1140 1150 1160 1170
1230 1240 1250 1260 1270 1280
pF1KE2 NRAYMRNPSSSVPPPSAGSVKTSTTGVATTQSPTPRSHSPSASQSGSQLRNRSVSGKRIC
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NRAYMRNPSSSVPPPSAGSVKTSTTGVATTQSPTPRSHSPSASQSGSQLRNSVLPVSVTS
1180 1190 1200 1210 1220 1230
1290 1300 1310 1320 1330 1340
pF1KE2 SYCNNILGKGAAMIIESLGLCYHLHCFKCVACECDLGGSSSGAEVRIRNHQLYCNDCYLR
XP_016 EALPQELKSGSETTNCTATTAISDSNLDGQPPCDVSLHTKALLQIEEEVVAAHVDL
1240 1250 1260 1270 1280 1290
>--
initn: 558 init1: 497 opt: 497 Z-score: 276.6 bits: 63.5 E(88908): 1.2e-08
Smith-Waterman score: 497; 97.3% identity (97.3% similar) in 74 aa overlap (286-359:1-74)
260 270 280 290 300 310
pF1KE2 RSLTSCSSDITLRGGREGFESDTDSEFTFKMQDYNKDDMSYRRISAVEPKTALPFNRFLP
::::::::::::::::::::::::::::::
XP_016 MQDYNKDDMSYRRISAVEPKTALPFNRFLP
10 20 30
320 330 340 350 360 370
pF1KE2 NKSRQPSYVPAPLRKKKPDKHEDNRRSWASPVYTEADGTFSRLFQKIYGENGSKSMSDVS
::::::::::::::::::::::::::::::::::::::::: :
XP_016 NKSRQPSYVPAPLRKKKPDKHEDNRRSWASPVYTEADGTFSSQFLLLQALQTYSDDILSS
40 50 60 70 80 90
380 390 400 410 420 430
pF1KE2 AEDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQ
XP_016 ETHTKIDPTSGPRLITRRKNLSYAPGYRRDDLEMAALDPDLENDDFFVRKTGAFHANPYV
100 110 120 130 140 150
1349 residues in 1 query sequences
63214209 residues in 88908 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Sep 21 11:32:36 2017 done: Thu Sep 21 11:32:39 2017
Total Scan time: 19.410 Total Display time: 0.490
Function used was FASTA [36.3.4 Apr, 2011]