Result of FASTA (omim) for
pFN21AE2685
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2685, 456 aa
1>>>pF1KE2685 456 - 456 aa - 456 aa
Library: /omim/omim.rfq.tfa
62035967 residues in 87258 sequences
Statistics: Expectation_n fit: rho(ln(x))= 13.2398+/-0.000405; mu= -17.1567+/- 0.025
mean_var=527.2845+/-109.120, 0's: 0 Z-trim(124.9): 59 B-trim: 488 in 1/59
Lambda= 0.055854
statistics sampled from 48095 (48166) to 48095 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.813), E-opt: 0.2 (0.552), width: 16
Scan time: 10.310
The best scores are: opt bits E(87258)
NP_006031 (OMIM: 604059) heparan sulfate glucosami ( 456) 3155 268.4 2.8e-71
NP_006033 (OMIM: 604057) heparan sulfate glucosami ( 406) 1436 129.9 1.3e-29
NP_006032 (OMIM: 604058) heparan sulfate glucosami ( 390) 1433 129.6 1.5e-29
NP_006034 (OMIM: 604056) heparan sulfate glucosami ( 367) 1431 129.4 1.6e-29
XP_011522416 (OMIM: 604057) PREDICTED: heparan sul ( 207) 1114 103.7 5.1e-22
XP_016880968 (OMIM: 604058) PREDICTED: heparan sul ( 203) 1111 103.4 5.9e-22
XP_011533890 (OMIM: 609407) PREDICTED: heparan sul ( 346) 840 81.8 3.3e-15
XP_016865963 (OMIM: 609407) PREDICTED: heparan sul ( 346) 840 81.8 3.3e-15
XP_016865960 (OMIM: 609407) PREDICTED: heparan sul ( 346) 840 81.8 3.3e-15
XP_016865959 (OMIM: 609407) PREDICTED: heparan sul ( 346) 840 81.8 3.3e-15
XP_016865962 (OMIM: 609407) PREDICTED: heparan sul ( 346) 840 81.8 3.3e-15
NP_705840 (OMIM: 609407) heparan sulfate glucosami ( 346) 840 81.8 3.3e-15
XP_006715442 (OMIM: 609407) PREDICTED: heparan sul ( 346) 840 81.8 3.3e-15
XP_016865961 (OMIM: 609407) PREDICTED: heparan sul ( 346) 840 81.8 3.3e-15
NP_005105 (OMIM: 603244) heparan sulfate glucosami ( 307) 789 77.6 5.2e-14
XP_011512215 (OMIM: 603244) PREDICTED: heparan sul ( 307) 789 77.6 5.2e-14
XP_016864331 (OMIM: 603950) PREDICTED: bifunctiona ( 493) 419 48.0 7e-05
XP_006714479 (OMIM: 603950) PREDICTED: bifunctiona ( 873) 419 48.2 0.00011
NP_004775 (OMIM: 603950) bifunctional heparan sulf ( 873) 419 48.2 0.00011
XP_016864035 (OMIM: 615039) PREDICTED: bifunctiona ( 493) 407 47.0 0.00014
XP_016864034 (OMIM: 615039) PREDICTED: bifunctiona ( 493) 407 47.0 0.00014
NP_072091 (OMIM: 615039) bifunctional heparan sulf ( 872) 407 47.2 0.00021
XP_016864332 (OMIM: 603950) PREDICTED: bifunctiona ( 484) 395 46.1 0.00026
XP_016872346 (OMIM: 603268) PREDICTED: bifunctiona ( 406) 392 45.8 0.00027
XP_016864330 (OMIM: 603950) PREDICTED: bifunctiona ( 519) 395 46.1 0.00028
XP_016864333 (OMIM: 603950) PREDICTED: bifunctiona ( 519) 395 46.1 0.00028
XP_005270313 (OMIM: 603268) PREDICTED: bifunctiona ( 509) 392 45.8 0.00032
XP_016864329 (OMIM: 603950) PREDICTED: bifunctiona ( 899) 395 46.3 0.00042
XP_016864328 (OMIM: 603950) PREDICTED: bifunctiona ( 899) 395 46.3 0.00042
NP_003626 (OMIM: 603268) bifunctional heparan sulf ( 883) 392 46.0 0.00048
XP_011538612 (OMIM: 603268) PREDICTED: bifunctiona ( 883) 392 46.0 0.00048
XP_016864922 (OMIM: 600853,616116) PREDICTED: bifu ( 553) 375 44.5 0.00089
XP_016864920 (OMIM: 600853,616116) PREDICTED: bifu ( 882) 375 44.7 0.0013
XP_016864918 (OMIM: 600853,616116) PREDICTED: bifu ( 882) 375 44.7 0.0013
XP_016864917 (OMIM: 600853,616116) PREDICTED: bifu ( 882) 375 44.7 0.0013
NP_001534 (OMIM: 600853,616116) bifunctional hepar ( 882) 375 44.7 0.0013
XP_006714846 (OMIM: 600853,616116) PREDICTED: bifu ( 882) 375 44.7 0.0013
XP_016864919 (OMIM: 600853,616116) PREDICTED: bifu ( 882) 375 44.7 0.0013
XP_005268499 (OMIM: 600853,616116) PREDICTED: bifu ( 471) 348 42.3 0.0036
XP_016864921 (OMIM: 600853,616116) PREDICTED: bifu ( 566) 348 42.3 0.0041
XP_011535940 (OMIM: 600853,616116) PREDICTED: bifu ( 566) 348 42.3 0.0041
XP_005268491 (OMIM: 600853,616116) PREDICTED: bifu ( 895) 348 42.5 0.0057
XP_005268492 (OMIM: 600853,616116) PREDICTED: bifu ( 895) 348 42.5 0.0057
XP_005268493 (OMIM: 600853,616116) PREDICTED: bifu ( 895) 348 42.5 0.0057
XP_016864916 (OMIM: 600853,616116) PREDICTED: bifu ( 895) 348 42.5 0.0057
XP_005268490 (OMIM: 600853,616116) PREDICTED: bifu ( 895) 348 42.5 0.0057
XP_005268494 (OMIM: 600853,616116) PREDICTED: bifu ( 895) 348 42.5 0.0057
XP_006714845 (OMIM: 600853,616116) PREDICTED: bifu ( 895) 348 42.5 0.0057
XP_016880969 (OMIM: 604057) PREDICTED: heparan sul ( 231) 329 40.5 0.0061
XP_011544303 (OMIM: 604056) PREDICTED: heparan sul ( 204) 326 40.2 0.0065
>>NP_006031 (OMIM: 604059) heparan sulfate glucosamine 3 (456 aa)
initn: 3155 init1: 3155 opt: 3155 Z-score: 1400.8 bits: 268.4 E(87258): 2.8e-71
Smith-Waterman score: 3155; 99.8% identity (100.0% similar) in 456 aa overlap (1-456:1-456)
10 20 30 40 50 60
pF1KE2 MARWPAPPPPPPPPPPLAAPPPPGASAKGPPARKLLFMCTLSLSVTYLCYSLLGGSGSLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MARWPAPPPPPPPPPPLAAPPPPGASAKGPPARKLLFMCTLSLSVTYLCYSLLGGSGSLQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 FPLALQESPGAAAEPPPSPPPPSLLPTPVRLGAPSQPPAPPPLDNASHGEPPEPPEQPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 FPLALQESPGAAAEPPPSPPPPSLLPTPVRLGAPSQPPAPPPLDNASHGEPPEPPEQPAA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 PGTDGWGLPSGGGGARDAWLRTPLAPSEMITAQSALPEREAQESSTTDEDLAGRRAANGS
:::::::::::::::.::::::::::::::::::::::::::::::::::::::::::::
NP_006 PGTDGWGLPSGGGGAQDAWLRTPLAPSEMITAQSALPEREAQESSTTDEDLAGRRAANGS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 SERGGAVSTPDYGEKKLPQALIIGVKKGGTRALLEAIRVHPDVRAVGVEPHFFDRNYEKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SERGGAVSTPDYGEKKLPQALIIGVKKGGTRALLEAIRVHPDVRAVGVEPHFFDRNYEKG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 LEWYRNVMPKTLDGQITMEKTPSYFVTNEAPKRIHSMAKDIKLIVVVRNPVTRAISDYTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LEWYRNVMPKTLDGQITMEKTPSYFVTNEAPKRIHSMAKDIKLIVVVRNPVTRAISDYTQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 TLSKKPEIPTFEVLAFKNRTLGLIDASWSAIRIGIYALHLENWLQYFPLSQILFVSGERL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 TLSKKPEIPTFEVLAFKNRTLGLIDASWSAIRIGIYALHLENWLQYFPLSQILFVSGERL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 IVDPAGEMAKVQDFLGLKRVVTEKHFYFNKTKGFPCLKKPEDSSAPRCLGKSKGRTHPRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 IVDPAGEMAKVQDFLGLKRVVTEKHFYFNKTKGFPCLKKPEDSSAPRCLGKSKGRTHPRI
370 380 390 400 410 420
430 440 450
pF1KE2 DPDVIHRLRKFYKPFNLMFYQMTGQDFQWEQEEGDK
::::::::::::::::::::::::::::::::::::
NP_006 DPDVIHRLRKFYKPFNLMFYQMTGQDFQWEQEEGDK
430 440 450
>>NP_006033 (OMIM: 604057) heparan sulfate glucosamine 3 (406 aa)
initn: 1456 init1: 1412 opt: 1436 Z-score: 652.8 bits: 129.9 E(87258): 1.3e-29
Smith-Waterman score: 1455; 64.2% identity (80.4% similar) in 352 aa overlap (122-450:59-405)
100 110 120 130 140
pF1KE2 GAPSQPPAPPPLDNASHGEPPEPPEQPAAPGTDGWGLPSGG---GGARD--AWLRTPLAP
: . : :.:: :: :. .: : :
NP_006 LCSLLTSLYVFYCLAERCQTLSGPVVGLSGGGEEAGAPGGGVLAGGPRELAVW---PAAA
30 40 50 60 70 80
150 160 170 180 190
pF1KE2 SEMITAQSALPE---------REAQESSTTDEDLAGRRAANGSSERGGAVS-TP------
.. : ::. :. : .. .:. : .. :.: :..:. .:
NP_006 QRKRLLQ--LPQWRRRRPPAPRDDGEEAAWEEESPGLSGGPGGSGAGSTVAEAPPGTLAL
90 100 110 120 130 140
200 210 220 230 240
pF1KE2 --DYGEKKLPQALIIGVKKGGTRALLEAIRVHPDVRAVGVEPHFFDRNYEKGLEWYRNVM
: : :.::::.:::::::::::::: .::::::::::.:::::::.:.::: :::..:
NP_006 LLDEGSKQLPQAIIIGVKKGGTRALLEFLRVHPDVRAVGAEPHFFDRSYDKGLAWYRDLM
150 160 170 180 190 200
250 260 270 280 290 300
pF1KE2 PKTLDGQITMEKTPSYFVTNEAPKRIHSMAKDIKLIVVVRNPVTRAISDYTQTLSKKPEI
:.::::::::::::::::: ::: :: .:.:: :::::::.:::::::::::::::.:.:
NP_006 PRTLDGQITMEKTPSYFVTREAPARISAMSKDTKLIVVVRDPVTRAISDYTQTLSKRPDI
210 220 230 240 250 260
310 320 330 340 350 360
pF1KE2 PTFEVLAFKNRTLGLIDASWSAIRIGIYALHLENWLQYFPLSQILFVSGERLIVDPAGEM
:::: :.::::: ::::.:::::.::::: :::.::..::. :.::::::::: :::::.
NP_006 PTFESLTFKNRTAGLIDTSWSAIQIGIYAKHLEHWLRHFPIRQMLFVSGERLISDPAGEL
270 280 290 300 310 320
370 380 390 400 410 420
pF1KE2 AKVQDFLGLKRVVTEKHFYFNKTKGFPCLKKPEDSSAPRCLGKSKGRTHPRIDPDVIHRL
..:::::::::..:.:::::::::::::::: : :: :.::::.::::::.:: .:..::
NP_006 GRVQDFLGLKRIITDKHFYFNKTKGFPCLKKAEGSSRPHCLGKTKGRTHPEIDREVVRRL
330 340 350 360 370 380
430 440 450
pF1KE2 RKFYKPFNLMFYQMTGQDFQWEQEEGDK
:.::.:::: ::::::.:: :.
NP_006 REFYRPFNLKFYQMTGHDFGWDG
390 400
>>NP_006032 (OMIM: 604058) heparan sulfate glucosamine 3 (390 aa)
initn: 1548 init1: 1412 opt: 1433 Z-score: 651.8 bits: 129.6 E(87258): 1.5e-29
Smith-Waterman score: 1469; 55.4% identity (70.6% similar) in 442 aa overlap (10-450:20-390)
10 20 30 40 50
pF1KE2 MARWPAPPPPPPPPPPLAAPPPPGASAKGPPARKLLFMCTLSLSVTYLCY
: ::::: ::.:. :.: ..::
NP_006 MGQRLSGGRSCLDVPGRLLPQPPPPP-------------PPVRR-----KLALLFAMLCV
10 20 30 40
60 70 80 90 100
pF1KE2 SLLGGSGSLQFPLALQESPGAAAEPPPSPPPPSLLPTPVRLGAPSQPPAPPP-LDNASHG
: . : :. : : .:: ::. :. :: : .: :
NP_006 WLY---------MFLYSCAGSCAAAP------GLL----LLGSGSRAAHDPPALATAPDG
50 60 70 80
110 120 130 140 150 160
pF1KE2 EPPEPPEQPAAPGTDGWGLPSGGGGARDAWLRTPLAPSEMITAQSALPEREAQESSTTDE
::. : . :: :. :::: .. .. .: ::... : .
NP_006 TPPRLPFR--AP-------PA-----------TPLASGKEMAEGAASPEEQSPEVPDSPS
90 100 110 120
170 180 190 200 210 220
pF1KE2 DLAGRRAANGSSERGGAVSTPDYGEKKLPQALIIGVKKGGTRALLEAIRVHPDVRAVGVE
... ...:: :.::::.:::::::::::::: .::::::::::.:
NP_006 PISSFFSGSGS--------------KQLPQAIIIGVKKGGTRALLEFLRVHPDVRAVGAE
130 140 150 160
230 240 250 260 270 280
pF1KE2 PHFFDRNYEKGLEWYRNVMPKTLDGQITMEKTPSYFVTNEAPKRIHSMAKDIKLIVVVRN
::::::.:.::: :::..::.::::::::::::::::: ::: :: .:.:: :::::::.
NP_006 PHFFDRSYDKGLAWYRDLMPRTLDGQITMEKTPSYFVTREAPARISAMSKDTKLIVVVRD
170 180 190 200 210 220
290 300 310 320 330 340
pF1KE2 PVTRAISDYTQTLSKKPEIPTFEVLAFKNRTLGLIDASWSAIRIGIYALHLENWLQYFPL
:::::::::::::::.:.::::: :.::::: ::::.:::::.::::: :::.::..::.
NP_006 PVTRAISDYTQTLSKRPDIPTFESLTFKNRTAGLIDTSWSAIQIGIYAKHLEHWLRHFPI
230 240 250 260 270 280
350 360 370 380 390 400
pF1KE2 SQILFVSGERLIVDPAGEMAKVQDFLGLKRVVTEKHFYFNKTKGFPCLKKPEDSSAPRCL
:.::::::::: :::::...:::::::::..:.:::::::::::::::: : :: :.::
NP_006 RQMLFVSGERLISDPAGELGRVQDFLGLKRIITDKHFYFNKTKGFPCLKKAEGSSRPHCL
290 300 310 320 330 340
410 420 430 440 450
pF1KE2 GKSKGRTHPRIDPDVIHRLRKFYKPFNLMFYQMTGQDFQWEQEEGDK
::.::::::.:: .:..:::.::.:::: ::::::.:: :.
NP_006 GKTKGRTHPEIDREVVRRLREFYRPFNLKFYQMTGHDFGWD
350 360 370 380 390
>>NP_006034 (OMIM: 604056) heparan sulfate glucosamine 3 (367 aa)
initn: 1543 init1: 1427 opt: 1431 Z-score: 651.2 bits: 129.4 E(87258): 1.6e-29
Smith-Waterman score: 1451; 56.9% identity (72.4% similar) in 427 aa overlap (29-450:10-367)
10 20 30 40 50
pF1KE2 MARWPAPPPPPPPPPPLAAPPPPGASAKGPP----ARKLLFMCTLSLSVTYLCYSLLGGS
::: ::.::: ::::: ::::::.:
NP_006 MAYRVLGRAGPPQPRRARRLLFAFTLSLSCTYLCYSFLCCC
10 20 30 40
60 70 80 90 100 110
pF1KE2 GSLQFPLALQESPGAAAEPPPSPPPPSLLPTPVRLGAPSQPPAPPPLDNASHGEPPEP-P
.: : . :: .: : .:: . :... .: : :
NP_006 DDL----------GRS----------RLLGAPRCLRGPSAG-GQKLLQKSRPCDPSGPTP
50 60 70 80
120 130 140 150 160 170
pF1KE2 EQPAAPGTDGWGLPSGGGGARDAWLRTPLAPSEMITAQSALPEREAQESSTTDEDLAGRR
.:.::. ::. .:.: : :
NP_006 SEPSAPS----------------------APA------AAVP--------------APR-
90
180 190 200 210 220 230
pF1KE2 AANGSSERGGAVSTPDYGEKKLPQALIIGVKKGGTRALLEAIRVHPDVRAVGVEPHFFDR
.::.. : .: : :.::::::.:::::::::.:: :::::::::.:.:::::::
NP_006 -LSGSNHSG----SPKLGTKRLPQALIVGVKKGGTRAVLEFIRVHPDVRALGTEPHFFDR
100 110 120 130 140 150
240 250 260 270 280 290
pF1KE2 NYEKGLEWYRNVMPKTLDGQITMEKTPSYFVTNEAPKRIHSMAKDIKLIVVVRNPVTRAI
:: .::.:::..::.::..:::.:::::::::.:::.:: .:..: ::::::::::::::
NP_006 NYGRGLDWYRSLMPRTLESQITLEKTPSYFVTQEAPRRIFNMSRDTKLIVVVRNPVTRAI
160 170 180 190 200 210
300 310 320 330 340 350
pF1KE2 SDYTQTLSKKPEIPTFEVLAFKNRTLGLIDASWSAIRIGIYALHLENWLQYFPLSQILFV
:::::::::::.::::: :.:.::::::.:.::.:::::.:.::::.:::::::.:: ::
NP_006 SDYTQTLSKKPDIPTFEGLSFRNRTLGLVDVSWNAIRIGMYVLHLESWLQYFPLAQIHFV
220 230 240 250 260 270
360 370 380 390 400 410
pF1KE2 SGERLIVDPAGEMAKVQDFLGLKRVVTEKHFYFNKTKGFPCLKKPEDSSAPRCLGKSKGR
::::::.::::::..::::::.:: .:.:::::::::::::::: :.: ::::::::::
NP_006 SGERLITDPAGEMGRVQDFLGIKRFITDKHFYFNKTKGFPCLKKTESSLLPRCLGKSKGR
280 290 300 310 320 330
420 430 440 450
pF1KE2 THPRIDPDVIHRLRKFYKPFNLMFYQMTGQDFQWEQEEGDK
:: .:::.:: .::.::.:.:. ::. .::::.::
NP_006 THVQIDPEVIDQLREFYRPYNIKFYETVGQDFRWE
340 350 360
>>XP_011522416 (OMIM: 604057) PREDICTED: heparan sulfate (207 aa)
initn: 1111 init1: 1111 opt: 1114 Z-score: 516.5 bits: 103.7 E(87258): 5.1e-22
Smith-Waterman score: 1114; 77.1% identity (92.7% similar) in 205 aa overlap (246-450:2-206)
220 230 240 250 260 270
pF1KE2 AIRVHPDVRAVGVEPHFFDRNYEKGLEWYRNVMPKTLDGQITMEKTPSYFVTNEAPKRIH
..::.::::::::::::::::: ::: ::
XP_011 MDLMPRTLDGQITMEKTPSYFVTREAPARIS
10 20 30
280 290 300 310 320 330
pF1KE2 SMAKDIKLIVVVRNPVTRAISDYTQTLSKKPEIPTFEVLAFKNRTLGLIDASWSAIRIGI
.:.:: :::::::.:::::::::::::::.:.::::: :.::::: ::::.:::::.:::
XP_011 AMSKDTKLIVVVRDPVTRAISDYTQTLSKRPDIPTFESLTFKNRTAGLIDTSWSAIQIGI
40 50 60 70 80 90
340 350 360 370 380 390
pF1KE2 YALHLENWLQYFPLSQILFVSGERLIVDPAGEMAKVQDFLGLKRVVTEKHFYFNKTKGFP
:: :::.::..::. :.::::::::: :::::...:::::::::..:.::::::::::::
XP_011 YAKHLEHWLRHFPIRQMLFVSGERLISDPAGELGRVQDFLGLKRIITDKHFYFNKTKGFP
100 110 120 130 140 150
400 410 420 430 440 450
pF1KE2 CLKKPEDSSAPRCLGKSKGRTHPRIDPDVIHRLRKFYKPFNLMFYQMTGQDFQWEQEEGD
:::: : :: :.::::.::::::.:: .:..:::.::.:::: ::::::.:: :.
XP_011 CLKKAEGSSRPHCLGKTKGRTHPEIDREVVRRLREFYRPFNLKFYQMTGHDFGWDG
160 170 180 190 200
pF1KE2 K
>>XP_016880968 (OMIM: 604058) PREDICTED: heparan sulfate (203 aa)
initn: 1111 init1: 1111 opt: 1111 Z-score: 515.3 bits: 103.4 E(87258): 5.9e-22
Smith-Waterman score: 1111; 77.8% identity (92.6% similar) in 203 aa overlap (248-450:1-203)
220 230 240 250 260 270
pF1KE2 RVHPDVRAVGVEPHFFDRNYEKGLEWYRNVMPKTLDGQITMEKTPSYFVTNEAPKRIHSM
::.::::::::::::::::: ::: :: .:
XP_016 MPRTLDGQITMEKTPSYFVTREAPARISAM
10 20 30
280 290 300 310 320 330
pF1KE2 AKDIKLIVVVRNPVTRAISDYTQTLSKKPEIPTFEVLAFKNRTLGLIDASWSAIRIGIYA
.:: :::::::.:::::::::::::::.:.::::: :.::::: ::::.:::::.:::::
XP_016 SKDTKLIVVVRDPVTRAISDYTQTLSKRPDIPTFESLTFKNRTAGLIDTSWSAIQIGIYA
40 50 60 70 80 90
340 350 360 370 380 390
pF1KE2 LHLENWLQYFPLSQILFVSGERLIVDPAGEMAKVQDFLGLKRVVTEKHFYFNKTKGFPCL
:::.::..::. :.::::::::: :::::...:::::::::..:.::::::::::::::
XP_016 KHLEHWLRHFPIRQMLFVSGERLISDPAGELGRVQDFLGLKRIITDKHFYFNKTKGFPCL
100 110 120 130 140 150
400 410 420 430 440 450
pF1KE2 KKPEDSSAPRCLGKSKGRTHPRIDPDVIHRLRKFYKPFNLMFYQMTGQDFQWEQEEGDK
:: : :: :.::::.::::::.:: .:..:::.::.:::: ::::::.:: :.
XP_016 KKAEGSSRPHCLGKTKGRTHPEIDREVVRRLREFYRPFNLKFYQMTGHDFGWD
160 170 180 190 200
>>XP_011533890 (OMIM: 609407) PREDICTED: heparan sulfate (346 aa)
initn: 847 init1: 289 opt: 840 Z-score: 394.2 bits: 81.8 E(87258): 3.3e-15
Smith-Waterman score: 840; 44.2% identity (70.3% similar) in 317 aa overlap (143-449:39-345)
120 130 140 150 160
pF1KE2 EPPEQPAAPGTDGWGLPSGGGGARDAWLRTPLAPSEM----ITAQSALPEREAQESSTTD
:. : : .:. .: : : .
XP_011 LRQKLLVLGSLAVGSLLYLVARVGSLDRLQPICPIEGRLGGARTQAEFPLRALQFKRGLL
10 20 30 40 50 60
170 180 190 200 210 220
pF1KE2 EDLAGRRAANGSSERGGAVSTPDYGEKKLPQALIIGVKKGGTRALLEAIRVHPDVRAVGV
... : .:.:.:. : : ..::.:.::::.::::::::: . .:: : ..
XP_011 HEF---RKGNASKEQ---VRLHDL-VQQLPKAIIIGVRKGGTRALLEMLNLHPAVVKASQ
70 80 90 100 110 120
230 240 250 260 270 280
pF1KE2 EPHFFD--RNYEKGLEWYRNVMPKTLDGQITMEKTPSYFVTNEAPKRIHSMAKDIKLIVV
: :::: .:: ::.::::. :: . :::.::.:.::.:.:.:.::..: ..:::...
XP_011 EIHFFDNDENYGKGIEWYRKKMPFSYPQQITIEKSPAYFITEEVPERIYKMNSSIKLLII
130 140 150 160 170 180
290 300 310 320 330 340
pF1KE2 VRNPVTRAISDYTQTLS----KKPEIPTFEVLAFKNRTLGLIDASWSAIRIGIYALHLEN
::.:.:::::::::.: :. :: ::. : ......:.: .::. :::
XP_011 VREPTTRAISDYTQVLEGKERKNKTYYKFEKLAIDPNTCE-VNTKYKAVRTSIYTKHLER
190 200 210 220 230 240
350 360 370 380 390 400
pF1KE2 WLQYFPLSQILFVSGERLIVDPAGEMAKVQDFLGLKRVVTEKHFYFNKTKGFPCLKKPED
::.:::. :. :.:.:::..: :. :. ::.: ... ..::: :.:: ::. .
XP_011 WLKYFPIEQFHVVDGDRLITEPLPELQLVEKFLNLPPRISQYNLYFNATRGFYCLR--FN
250 260 270 280 290
410 420 430 440 450
pF1KE2 SSAPRCLGKSKGRTHPRIDPDVIHRLRKFYKPFNLMFYQMTGQDFQWEQEEGDK
.::. :::: ::..::.:: .::::..::: :::.::. ..:
XP_011 IIFNKCLAGSKGRIHPEVDPSVITKLRKFFHPFNQKFYQITGRTLNWP
300 310 320 330 340
>>XP_016865963 (OMIM: 609407) PREDICTED: heparan sulfate (346 aa)
initn: 847 init1: 289 opt: 840 Z-score: 394.2 bits: 81.8 E(87258): 3.3e-15
Smith-Waterman score: 840; 44.2% identity (70.3% similar) in 317 aa overlap (143-449:39-345)
120 130 140 150 160
pF1KE2 EPPEQPAAPGTDGWGLPSGGGGARDAWLRTPLAPSEM----ITAQSALPEREAQESSTTD
:. : : .:. .: : : .
XP_016 LRQKLLVLGSLAVGSLLYLVARVGSLDRLQPICPIEGRLGGARTQAEFPLRALQFKRGLL
10 20 30 40 50 60
170 180 190 200 210 220
pF1KE2 EDLAGRRAANGSSERGGAVSTPDYGEKKLPQALIIGVKKGGTRALLEAIRVHPDVRAVGV
... : .:.:.:. : : ..::.:.::::.::::::::: . .:: : ..
XP_016 HEF---RKGNASKEQ---VRLHDL-VQQLPKAIIIGVRKGGTRALLEMLNLHPAVVKASQ
70 80 90 100 110 120
230 240 250 260 270 280
pF1KE2 EPHFFD--RNYEKGLEWYRNVMPKTLDGQITMEKTPSYFVTNEAPKRIHSMAKDIKLIVV
: :::: .:: ::.::::. :: . :::.::.:.::.:.:.:.::..: ..:::...
XP_016 EIHFFDNDENYGKGIEWYRKKMPFSYPQQITIEKSPAYFITEEVPERIYKMNSSIKLLII
130 140 150 160 170 180
290 300 310 320 330 340
pF1KE2 VRNPVTRAISDYTQTLS----KKPEIPTFEVLAFKNRTLGLIDASWSAIRIGIYALHLEN
::.:.:::::::::.: :. :: ::. : ......:.: .::. :::
XP_016 VREPTTRAISDYTQVLEGKERKNKTYYKFEKLAIDPNTCE-VNTKYKAVRTSIYTKHLER
190 200 210 220 230 240
350 360 370 380 390 400
pF1KE2 WLQYFPLSQILFVSGERLIVDPAGEMAKVQDFLGLKRVVTEKHFYFNKTKGFPCLKKPED
::.:::. :. :.:.:::..: :. :. ::.: ... ..::: :.:: ::. .
XP_016 WLKYFPIEQFHVVDGDRLITEPLPELQLVEKFLNLPPRISQYNLYFNATRGFYCLR--FN
250 260 270 280 290
410 420 430 440 450
pF1KE2 SSAPRCLGKSKGRTHPRIDPDVIHRLRKFYKPFNLMFYQMTGQDFQWEQEEGDK
.::. :::: ::..::.:: .::::..::: :::.::. ..:
XP_016 IIFNKCLAGSKGRIHPEVDPSVITKLRKFFHPFNQKFYQITGRTLNWP
300 310 320 330 340
>>XP_016865960 (OMIM: 609407) PREDICTED: heparan sulfate (346 aa)
initn: 847 init1: 289 opt: 840 Z-score: 394.2 bits: 81.8 E(87258): 3.3e-15
Smith-Waterman score: 840; 44.2% identity (70.3% similar) in 317 aa overlap (143-449:39-345)
120 130 140 150 160
pF1KE2 EPPEQPAAPGTDGWGLPSGGGGARDAWLRTPLAPSEM----ITAQSALPEREAQESSTTD
:. : : .:. .: : : .
XP_016 LRQKLLVLGSLAVGSLLYLVARVGSLDRLQPICPIEGRLGGARTQAEFPLRALQFKRGLL
10 20 30 40 50 60
170 180 190 200 210 220
pF1KE2 EDLAGRRAANGSSERGGAVSTPDYGEKKLPQALIIGVKKGGTRALLEAIRVHPDVRAVGV
... : .:.:.:. : : ..::.:.::::.::::::::: . .:: : ..
XP_016 HEF---RKGNASKEQ---VRLHDL-VQQLPKAIIIGVRKGGTRALLEMLNLHPAVVKASQ
70 80 90 100 110 120
230 240 250 260 270 280
pF1KE2 EPHFFD--RNYEKGLEWYRNVMPKTLDGQITMEKTPSYFVTNEAPKRIHSMAKDIKLIVV
: :::: .:: ::.::::. :: . :::.::.:.::.:.:.:.::..: ..:::...
XP_016 EIHFFDNDENYGKGIEWYRKKMPFSYPQQITIEKSPAYFITEEVPERIYKMNSSIKLLII
130 140 150 160 170 180
290 300 310 320 330 340
pF1KE2 VRNPVTRAISDYTQTLS----KKPEIPTFEVLAFKNRTLGLIDASWSAIRIGIYALHLEN
::.:.:::::::::.: :. :: ::. : ......:.: .::. :::
XP_016 VREPTTRAISDYTQVLEGKERKNKTYYKFEKLAIDPNTCE-VNTKYKAVRTSIYTKHLER
190 200 210 220 230 240
350 360 370 380 390 400
pF1KE2 WLQYFPLSQILFVSGERLIVDPAGEMAKVQDFLGLKRVVTEKHFYFNKTKGFPCLKKPED
::.:::. :. :.:.:::..: :. :. ::.: ... ..::: :.:: ::. .
XP_016 WLKYFPIEQFHVVDGDRLITEPLPELQLVEKFLNLPPRISQYNLYFNATRGFYCLR--FN
250 260 270 280 290
410 420 430 440 450
pF1KE2 SSAPRCLGKSKGRTHPRIDPDVIHRLRKFYKPFNLMFYQMTGQDFQWEQEEGDK
.::. :::: ::..::.:: .::::..::: :::.::. ..:
XP_016 IIFNKCLAGSKGRIHPEVDPSVITKLRKFFHPFNQKFYQITGRTLNWP
300 310 320 330 340
>>XP_016865959 (OMIM: 609407) PREDICTED: heparan sulfate (346 aa)
initn: 847 init1: 289 opt: 840 Z-score: 394.2 bits: 81.8 E(87258): 3.3e-15
Smith-Waterman score: 840; 44.2% identity (70.3% similar) in 317 aa overlap (143-449:39-345)
120 130 140 150 160
pF1KE2 EPPEQPAAPGTDGWGLPSGGGGARDAWLRTPLAPSEM----ITAQSALPEREAQESSTTD
:. : : .:. .: : : .
XP_016 LRQKLLVLGSLAVGSLLYLVARVGSLDRLQPICPIEGRLGGARTQAEFPLRALQFKRGLL
10 20 30 40 50 60
170 180 190 200 210 220
pF1KE2 EDLAGRRAANGSSERGGAVSTPDYGEKKLPQALIIGVKKGGTRALLEAIRVHPDVRAVGV
... : .:.:.:. : : ..::.:.::::.::::::::: . .:: : ..
XP_016 HEF---RKGNASKEQ---VRLHDL-VQQLPKAIIIGVRKGGTRALLEMLNLHPAVVKASQ
70 80 90 100 110 120
230 240 250 260 270 280
pF1KE2 EPHFFD--RNYEKGLEWYRNVMPKTLDGQITMEKTPSYFVTNEAPKRIHSMAKDIKLIVV
: :::: .:: ::.::::. :: . :::.::.:.::.:.:.:.::..: ..:::...
XP_016 EIHFFDNDENYGKGIEWYRKKMPFSYPQQITIEKSPAYFITEEVPERIYKMNSSIKLLII
130 140 150 160 170 180
290 300 310 320 330 340
pF1KE2 VRNPVTRAISDYTQTLS----KKPEIPTFEVLAFKNRTLGLIDASWSAIRIGIYALHLEN
::.:.:::::::::.: :. :: ::. : ......:.: .::. :::
XP_016 VREPTTRAISDYTQVLEGKERKNKTYYKFEKLAIDPNTCE-VNTKYKAVRTSIYTKHLER
190 200 210 220 230 240
350 360 370 380 390 400
pF1KE2 WLQYFPLSQILFVSGERLIVDPAGEMAKVQDFLGLKRVVTEKHFYFNKTKGFPCLKKPED
::.:::. :. :.:.:::..: :. :. ::.: ... ..::: :.:: ::. .
XP_016 WLKYFPIEQFHVVDGDRLITEPLPELQLVEKFLNLPPRISQYNLYFNATRGFYCLR--FN
250 260 270 280 290
410 420 430 440 450
pF1KE2 SSAPRCLGKSKGRTHPRIDPDVIHRLRKFYKPFNLMFYQMTGQDFQWEQEEGDK
.::. :::: ::..::.:: .::::..::: :::.::. ..:
XP_016 IIFNKCLAGSKGRIHPEVDPSVITKLRKFFHPFNQKFYQITGRTLNWP
300 310 320 330 340
456 residues in 1 query sequences
62035967 residues in 87258 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Jun 2 11:47:28 2017 done: Fri Jun 2 11:47:30 2017
Total Scan time: 10.310 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]