FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE2675, 324 aa
  1>>>pF1KE2675     324 - 324 aa - 324 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.1914+/-0.000838; mu= 16.7303+/- 0.050
 mean_var=67.4579+/-13.166, 0's: 0 Z-trim(107.0): 21  B-trim: 0 in 0/50
 Lambda= 0.156156
 statistics sampled from 9290 (9300) to 9290 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.665), E-opt: 0.2 (0.286), width:  16
 Scan time:  2.510

The best scores are:                                      opt bits E(32554)
CCDS586.1 TMEM59 gene_id:9528|Hs108|chr1           ( 323) 2149 492.9 1.4e-139
CCDS81329.1 TMEM59 gene_id:9528|Hs108|chr1         ( 192) 1242 288.5   3e-78
CCDS81330.1 TMEM59 gene_id:9528|Hs108|chr1         ( 145)  904 212.2   2e-55
CCDS12383.1 TMEM59L gene_id:25789|Hs108|chr19      ( 342)  380 94.4 1.4e-19


>>CCDS586.1 TMEM59 gene_id:9528|Hs108|chr1                (323 aa)
 initn: 1419 init1: 1419 opt: 2149  Z-score: 2619.4  bits: 492.9 E(32554): 1.4e-139
Smith-Waterman score: 2149; 99.4% identity (99.4% similar) in 324 aa overlap (1-324:1-323)

               10        20        30        40        50        60
pF1KE2 MAAPKGSLWVRTQLGLPPLLLLTMALAGGSGTASAEAFDSVLGDTASCHRACQLTYPLHT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 MAAPKGSLWVRTQLGLPPLLLLTMALAGGSGTASAEAFDSVLGDTASCHRACQLTYPLHT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 YPKEEELYACQRGCRLFSICQFVDDGIDLNRTKLECESACTEAYSQSDEQYACHLGCQNQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 YPKEEELYACQRGCRLFSICQFVDDGIDLNRTKLECESACTEAYSQSDEQYACHLGCQNQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 LPFAELRQEQLMSLMPKMHLLFPLTLVRSFWSDMMDSAQSFITSSWTFYLQADDGKIVIF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 LPFAELRQEQLMSLMPKMHLLFPLTLVRSFWSDMMDSAQSFITSSWTFYLQADDGKIVIF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 QSKPEIQYAPHLEQEPTNLRESSLSKMSSDLQMRNSQAHRNFLEDGESDGFLRCLSLNSG
       ::::::::::::::::::::::::::::  ::::::::::::::::::::::::::::::
CCDS58 QSKPEIQYAPHLEQEPTNLRESSLSKMSY-LQMRNSQAHRNFLEDGESDGFLRCLSLNSG
              190       200        210       220       230         

              250       260       270       280       290       300
pF1KE2 WILTTTLVLSVMVLLWICCATVATAVEQYVPSEKLSIYGDLEFMNEQKLNRYPASSLVVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 WILTTTLVLSVMVLLWICCATVATAVEQYVPSEKLSIYGDLEFMNEQKLNRYPASSLVVV
     240       250       260       270       280       290         

              310       320    
pF1KE2 RSKTEDHEEAGPLPTKVNLAHSEI
       ::::::::::::::::::::::::
CCDS58 RSKTEDHEEAGPLPTKVNLAHSEI
     300       310       320   

>>CCDS81329.1 TMEM59 gene_id:9528|Hs108|chr1              (192 aa)
 initn: 746 init1: 746 opt: 1242  Z-score: 1518.4  bits: 288.5 E(32554): 3e-78
Smith-Waterman score: 1242; 99.0% identity (99.0% similar) in 193 aa overlap (132-324:1-192)

             110       120       130       140       150       160 
pF1KE2 EAYSQSDEQYACHLGCQNQLPFAELRQEQLMSLMPKMHLLFPLTLVRSFWSDMMDSAQSF
                                     ::::::::::::::::::::::::::::::
CCDS81                               MSLMPKMHLLFPLTLVRSFWSDMMDSAQSF
                                             10        20        30

             170       180       190       200       210       220 
pF1KE2 ITSSWTFYLQADDGKIVIFQSKPEIQYAPHLEQEPTNLRESSLSKMSSDLQMRNSQAHRN
       :::::::::::::::::::::::::::::::::::::::::::::::  :::::::::::
CCDS81 ITSSWTFYLQADDGKIVIFQSKPEIQYAPHLEQEPTNLRESSLSKMSY-LQMRNSQAHRN
               40        50        60        70         80         

             230       240       250       260       270       280 
pF1KE2 FLEDGESDGFLRCLSLNSGWILTTTLVLSVMVLLWICCATVATAVEQYVPSEKLSIYGDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 FLEDGESDGFLRCLSLNSGWILTTTLVLSVMVLLWICCATVATAVEQYVPSEKLSIYGDL
      90       100       110       120       130       140         

             290       300       310       320    
pF1KE2 EFMNEQKLNRYPASSLVVVRSKTEDHEEAGPLPTKVNLAHSEI
       :::::::::::::::::::::::::::::::::::::::::::
CCDS81 EFMNEQKLNRYPASSLVVVRSKTEDHEEAGPLPTKVNLAHSEI
     150       160       170       180       190  

>>CCDS81330.1 TMEM59 gene_id:9528|Hs108|chr1              (145 aa)
 initn: 949 init1: 903 opt: 904  Z-score: 1108.6  bits: 212.2 E(32554): 2e-55
Smith-Waterman score: 904; 88.7% identity (92.1% similar) in 151 aa overlap (1-151:1-144)

               10        20        30        40        50        60
pF1KE2 MAAPKGSLWVRTQLGLPPLLLLTMALAGGSGTASAEAFDSVLGDTASCHRACQLTYPLHT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 MAAPKGSLWVRTQLGLPPLLLLTMALAGGSGTASAEAFDSVLGDTASCHRACQLTYPLHT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 YPKEEELYACQRGCRLFSICQFVDDGIDLNRTKLECESACTEAYSQSDEQYACHLGCQNQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 YPKEEELYACQRGCRLFSICQFVDDGIDLNRTKLECESACTEAYSQSDEQYACHLGCQNQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 LPFAELRQEQLMSLMPKMHLLFPLTLVRSFWSDMMDSAQSFITSSWTFYLQADDGKIVIF
       ::::::::::.     . .  :  .:.:  :                             
CCDS81 LPFAELRQEQV-----RNNTAFQTSLLR--WH                            
              130            140                                   

              190       200       210       220       230       240
pF1KE2 QSKPEIQYAPHLEQEPTNLRESSLSKMSSDLQMRNSQAHRNFLEDGESDGFLRCLSLNSG

>>CCDS12383.1 TMEM59L gene_id:25789|Hs108|chr19           (342 aa)
 initn: 533 init1: 221 opt: 380  Z-score: 465.2  bits: 94.4 E(32554): 1.4e-19
Smith-Waterman score: 545; 33.5% identity (58.6% similar) in 319 aa overlap (16-296:7-323)

               10        20           30        40        50       
pF1KE2 MAAPKGSLWVRTQLGLPPLLLLTMALAG---GSGTASAEAFDSVLGDTASCHRACQLTYP
                      .:: ::: . ::.   .:. .. . :   :::: .:.  :.    
CCDS12          MAAVALMPPPLLLLLLLASPPAASAPSARDPFAPQLGDTQNCQLRCR-DRD
                        10        20        30        40         50

        60                      70        80        90       100   
pF1KE2 LHTYPKEEELY--------------ACQRGCRLFSICQFVDDGIDLNRTKLECESACTEA
       :   :..  :               ::.:::::::::.::  .   : :. :::.::.::
CCDS12 LGPQPSQAGLEGASESPYDRAVLISACERGCRLFSICRFVARSSKPNATQTECEAACVEA
               60        70        80        90       100       110

           110       120       130       140       150       160   
pF1KE2 YSQSDEQYACHLGCQNQLPFAELRQEQLMSLMPKMHLLFPLTLVRSFWSDMMDSAQSFIT
       : .  :: ::  :: .:    : .:.. .   :.  : . : :  .. .:...:::.:..
CCDS12 YVKEAEQQACSHGCWSQPAEPEPEQKRKVLEAPSGALSL-LDLFSTLCNDLVNSAQGFVS
              120       130       140        150       160         

           170       180           190       200                   
pF1KE2 SSWTFYLQADDGKIVIFQSKPEIQ----YAPHLEQEPTNLRESS-------------LSK
       :.::.:::.:.::.:.::..: ..     . .:..  .. : :              :.:
CCDS12 STWTYYLQTDNGKVVVFQTQPIVESLGFQGGRLQRVEVTWRGSHPEALEVHVDPVGPLDK
     170       180       190       200       210       220         

         210       220       230       240          250       260  
pF1KE2 M-SSDLQMRNSQAHRNFLEDGESDGFLRCLSLNSG---WILTTTLVLSVMVLLWICCATV
       . .. .....:.  .   :. ... :: :.:  ::   :::.  : :::.:.::. :.:.
CCDS12 VRKAKIRVKTSSKAKVESEEPQDNDFLSCMSRRSGLPRWILACCLFLSVLVMLWLSCSTL
     230       240       250       260       270       280         

            270       280       290       300       310       320  
pF1KE2 ATAVEQYVPSEKLSIYGDLEFMNEQKLNRYPASSLVVVRSKTEDHEEAGPLPTKVNLAHS
       .::  :..  . :..     :: :     ::  :                          
CCDS12 VTAPGQHLKFQPLTLEQHKGFMMEPDWPLYPPPSHACEDSLPPYKLKLDLTKL       
     290       300       310       320       330       340         

         
pF1KE2 EI




324 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Feb  2 14:39:48 2017 done: Thu Feb  2 14:39:48 2017
 Total Scan time:  2.510 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]