Result of FASTA (ccds) for
pFN21AE2645
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2645, 638 aa
1>>>pF1KE2645 638 - 638 aa - 638 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.7001+/-0.000908; mu= 12.5570+/- 0.054
mean_var=89.7644+/-17.687, 0's: 0 Z-trim(107.5): 41 B-trim: 0 in 0/52
Lambda= 0.135370
statistics sampled from 9580 (9608) to 9580 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.664), E-opt: 0.2 (0.295), width: 16
Scan time: 3.400
The best scores are: opt bits E(32554)
CCDS3940.1 GHR gene_id:2690|Hs108|chr5 ( 638) 4350 859.9 0
CCDS75239.1 GHR gene_id:2690|Hs108|chr5 ( 645) 4350 859.9 0
CCDS56364.1 GHR gene_id:2690|Hs108|chr5 ( 616) 4060 803.2 0
CCDS75240.1 GHR gene_id:2690|Hs108|chr5 ( 295) 2006 402.0 6e-112
CCDS3909.1 PRLR gene_id:5618|Hs108|chr5 ( 622) 529 113.6 8e-25
CCDS56362.1 PRLR gene_id:5618|Hs108|chr5 ( 349) 523 112.4 1.1e-24
CCDS56361.1 PRLR gene_id:5618|Hs108|chr5 ( 376) 523 112.4 1.1e-24
CCDS56360.1 PRLR gene_id:5618|Hs108|chr5 ( 288) 451 98.3 1.5e-20
CCDS56359.1 PRLR gene_id:5618|Hs108|chr5 ( 268) 370 82.5 8.3e-16
CCDS56358.1 PRLR gene_id:5618|Hs108|chr5 ( 521) 354 79.4 1.3e-14
>>CCDS3940.1 GHR gene_id:2690|Hs108|chr5 (638 aa)
initn: 4350 init1: 4350 opt: 4350 Z-score: 4591.9 bits: 859.9 E(32554): 0
Smith-Waterman score: 4350; 100.0% identity (100.0% similar) in 638 aa overlap (1-638:1-638)
10 20 30 40 50 60
pF1KE2 MDLWQLLLTLALAGSSDAFSGSEATAAILSRAPWSLQSVNPGLKTNSSKEPKFTKCRSPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 MDLWQLLLTLALAGSSDAFSGSEATAAILSRAPWSLQSVNPGLKTNSSKEPKFTKCRSPE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 RETFSCHWTDEVHHGTKNLGPIQLFYTRRNTQEWTQEWKECPDYVSAGENSCYFNSSFTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 RETFSCHWTDEVHHGTKNLGPIQLFYTRRNTQEWTQEWKECPDYVSAGENSCYFNSSFTS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 IWIPYCIKLTSNGGTVDEKCFSVDEIVQPDPPIALNWTLLNVSLTGIHADIQVRWEAPRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 IWIPYCIKLTSNGGTVDEKCFSVDEIVQPDPPIALNWTLLNVSLTGIHADIQVRWEAPRN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 ADIQKGWMVLEYELQYKEVNETKWKMMDPILTTSVPVYSLKVDKEYEVRVRSKQRNSGNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 ADIQKGWMVLEYELQYKEVNETKWKMMDPILTTSVPVYSLKVDKEYEVRVRSKQRNSGNY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 GEFSEVLYVTLPQMSQFTCEEDFYFPWLLIIIFGIFGLTVMLFVFLFSKQQRIKMLILPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 GEFSEVLYVTLPQMSQFTCEEDFYFPWLLIIIFGIFGLTVMLFVFLFSKQQRIKMLILPP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 VPVPKIKGIDPDLLKEGKLEEVNTILAIHDSYKPEFHSDDSWVEFIELDIDEPDEKTEES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 VPVPKIKGIDPDLLKEGKLEEVNTILAIHDSYKPEFHSDDSWVEFIELDIDEPDEKTEES
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 DTDRLLSSDHEKSHSNLGVKDGDSGRTSCCEPDILETDFNANDIHEGTSEVAQPQRLKGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 DTDRLLSSDHEKSHSNLGVKDGDSGRTSCCEPDILETDFNANDIHEGTSEVAQPQRLKGE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 ADLLCLDQKNQNNSPYHDACPATQQPSVIQAEKNKPQPLPTEGAESTHQAAHIQLSNPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 ADLLCLDQKNQNNSPYHDACPATQQPSVIQAEKNKPQPLPTEGAESTHQAAHIQLSNPSS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 LSNIDFYAQVSDITPAGSVVLSPGQKNKAGMSQCDMHPEMVSLCQENFLMDNAYFCEADA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 LSNIDFYAQVSDITPAGSVVLSPGQKNKAGMSQCDMHPEMVSLCQENFLMDNAYFCEADA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 KKCIPVAPHIKVESHIQPSLNQEDIYITTESLTTAAGRPGTGEHVPGSEMPVPDYTSIHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 KKCIPVAPHIKVESHIQPSLNQEDIYITTESLTTAAGRPGTGEHVPGSEMPVPDYTSIHI
550 560 570 580 590 600
610 620 630
pF1KE2 VQSPQGLILNATALPLPDKEFLSSCGYVSTDQLNKIMP
::::::::::::::::::::::::::::::::::::::
CCDS39 VQSPQGLILNATALPLPDKEFLSSCGYVSTDQLNKIMP
610 620 630
>>CCDS75239.1 GHR gene_id:2690|Hs108|chr5 (645 aa)
initn: 4350 init1: 4350 opt: 4350 Z-score: 4591.8 bits: 859.9 E(32554): 0
Smith-Waterman score: 4350; 100.0% identity (100.0% similar) in 638 aa overlap (1-638:8-645)
10 20 30 40 50
pF1KE2 MDLWQLLLTLALAGSSDAFSGSEATAAILSRAPWSLQSVNPGLKTNSSKEPKF
:::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 MNWGPTGMDLWQLLLTLALAGSSDAFSGSEATAAILSRAPWSLQSVNPGLKTNSSKEPKF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 TKCRSPERETFSCHWTDEVHHGTKNLGPIQLFYTRRNTQEWTQEWKECPDYVSAGENSCY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 TKCRSPERETFSCHWTDEVHHGTKNLGPIQLFYTRRNTQEWTQEWKECPDYVSAGENSCY
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE2 FNSSFTSIWIPYCIKLTSNGGTVDEKCFSVDEIVQPDPPIALNWTLLNVSLTGIHADIQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 FNSSFTSIWIPYCIKLTSNGGTVDEKCFSVDEIVQPDPPIALNWTLLNVSLTGIHADIQV
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE2 RWEAPRNADIQKGWMVLEYELQYKEVNETKWKMMDPILTTSVPVYSLKVDKEYEVRVRSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 RWEAPRNADIQKGWMVLEYELQYKEVNETKWKMMDPILTTSVPVYSLKVDKEYEVRVRSK
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE2 QRNSGNYGEFSEVLYVTLPQMSQFTCEEDFYFPWLLIIIFGIFGLTVMLFVFLFSKQQRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 QRNSGNYGEFSEVLYVTLPQMSQFTCEEDFYFPWLLIIIFGIFGLTVMLFVFLFSKQQRI
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE2 KMLILPPVPVPKIKGIDPDLLKEGKLEEVNTILAIHDSYKPEFHSDDSWVEFIELDIDEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 KMLILPPVPVPKIKGIDPDLLKEGKLEEVNTILAIHDSYKPEFHSDDSWVEFIELDIDEP
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE2 DEKTEESDTDRLLSSDHEKSHSNLGVKDGDSGRTSCCEPDILETDFNANDIHEGTSEVAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 DEKTEESDTDRLLSSDHEKSHSNLGVKDGDSGRTSCCEPDILETDFNANDIHEGTSEVAQ
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE2 PQRLKGEADLLCLDQKNQNNSPYHDACPATQQPSVIQAEKNKPQPLPTEGAESTHQAAHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 PQRLKGEADLLCLDQKNQNNSPYHDACPATQQPSVIQAEKNKPQPLPTEGAESTHQAAHI
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE2 QLSNPSSLSNIDFYAQVSDITPAGSVVLSPGQKNKAGMSQCDMHPEMVSLCQENFLMDNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 QLSNPSSLSNIDFYAQVSDITPAGSVVLSPGQKNKAGMSQCDMHPEMVSLCQENFLMDNA
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE2 YFCEADAKKCIPVAPHIKVESHIQPSLNQEDIYITTESLTTAAGRPGTGEHVPGSEMPVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 YFCEADAKKCIPVAPHIKVESHIQPSLNQEDIYITTESLTTAAGRPGTGEHVPGSEMPVP
550 560 570 580 590 600
600 610 620 630
pF1KE2 DYTSIHIVQSPQGLILNATALPLPDKEFLSSCGYVSTDQLNKIMP
:::::::::::::::::::::::::::::::::::::::::::::
CCDS75 DYTSIHIVQSPQGLILNATALPLPDKEFLSSCGYVSTDQLNKIMP
610 620 630 640
>>CCDS56364.1 GHR gene_id:2690|Hs108|chr5 (616 aa)
initn: 4060 init1: 4060 opt: 4060 Z-score: 4286.1 bits: 803.2 E(32554): 0
Smith-Waterman score: 4151; 96.4% identity (96.6% similar) in 638 aa overlap (1-638:1-616)
10 20 30 40 50 60
pF1KE2 MDLWQLLLTLALAGSSDAFSGSEATAAILSRAPWSLQSVNPGLKTNSSKEPKFTKCRSPE
::::::::::::::::::::::: .::::::::::::::
CCDS56 MDLWQLLLTLALAGSSDAFSGSE----------------------DSSKEPKFTKCRSPE
10 20 30
70 80 90 100 110 120
pF1KE2 RETFSCHWTDEVHHGTKNLGPIQLFYTRRNTQEWTQEWKECPDYVSAGENSCYFNSSFTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 RETFSCHWTDEVHHGTKNLGPIQLFYTRRNTQEWTQEWKECPDYVSAGENSCYFNSSFTS
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE2 IWIPYCIKLTSNGGTVDEKCFSVDEIVQPDPPIALNWTLLNVSLTGIHADIQVRWEAPRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 IWIPYCIKLTSNGGTVDEKCFSVDEIVQPDPPIALNWTLLNVSLTGIHADIQVRWEAPRN
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE2 ADIQKGWMVLEYELQYKEVNETKWKMMDPILTTSVPVYSLKVDKEYEVRVRSKQRNSGNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 ADIQKGWMVLEYELQYKEVNETKWKMMDPILTTSVPVYSLKVDKEYEVRVRSKQRNSGNY
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE2 GEFSEVLYVTLPQMSQFTCEEDFYFPWLLIIIFGIFGLTVMLFVFLFSKQQRIKMLILPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 GEFSEVLYVTLPQMSQFTCEEDFYFPWLLIIIFGIFGLTVMLFVFLFSKQQRIKMLILPP
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE2 VPVPKIKGIDPDLLKEGKLEEVNTILAIHDSYKPEFHSDDSWVEFIELDIDEPDEKTEES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 VPVPKIKGIDPDLLKEGKLEEVNTILAIHDSYKPEFHSDDSWVEFIELDIDEPDEKTEES
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE2 DTDRLLSSDHEKSHSNLGVKDGDSGRTSCCEPDILETDFNANDIHEGTSEVAQPQRLKGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 DTDRLLSSDHEKSHSNLGVKDGDSGRTSCCEPDILETDFNANDIHEGTSEVAQPQRLKGE
340 350 360 370 380 390
430 440 450 460 470 480
pF1KE2 ADLLCLDQKNQNNSPYHDACPATQQPSVIQAEKNKPQPLPTEGAESTHQAAHIQLSNPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 ADLLCLDQKNQNNSPYHDACPATQQPSVIQAEKNKPQPLPTEGAESTHQAAHIQLSNPSS
400 410 420 430 440 450
490 500 510 520 530 540
pF1KE2 LSNIDFYAQVSDITPAGSVVLSPGQKNKAGMSQCDMHPEMVSLCQENFLMDNAYFCEADA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 LSNIDFYAQVSDITPAGSVVLSPGQKNKAGMSQCDMHPEMVSLCQENFLMDNAYFCEADA
460 470 480 490 500 510
550 560 570 580 590 600
pF1KE2 KKCIPVAPHIKVESHIQPSLNQEDIYITTESLTTAAGRPGTGEHVPGSEMPVPDYTSIHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 KKCIPVAPHIKVESHIQPSLNQEDIYITTESLTTAAGRPGTGEHVPGSEMPVPDYTSIHI
520 530 540 550 560 570
610 620 630
pF1KE2 VQSPQGLILNATALPLPDKEFLSSCGYVSTDQLNKIMP
::::::::::::::::::::::::::::::::::::::
CCDS56 VQSPQGLILNATALPLPDKEFLSSCGYVSTDQLNKIMP
580 590 600 610
>>CCDS75240.1 GHR gene_id:2690|Hs108|chr5 (295 aa)
initn: 2006 init1: 2006 opt: 2006 Z-score: 2123.3 bits: 402.0 E(32554): 6e-112
Smith-Waterman score: 2006; 100.0% identity (100.0% similar) in 292 aa overlap (1-292:1-292)
10 20 30 40 50 60
pF1KE2 MDLWQLLLTLALAGSSDAFSGSEATAAILSRAPWSLQSVNPGLKTNSSKEPKFTKCRSPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 MDLWQLLLTLALAGSSDAFSGSEATAAILSRAPWSLQSVNPGLKTNSSKEPKFTKCRSPE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 RETFSCHWTDEVHHGTKNLGPIQLFYTRRNTQEWTQEWKECPDYVSAGENSCYFNSSFTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 RETFSCHWTDEVHHGTKNLGPIQLFYTRRNTQEWTQEWKECPDYVSAGENSCYFNSSFTS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 IWIPYCIKLTSNGGTVDEKCFSVDEIVQPDPPIALNWTLLNVSLTGIHADIQVRWEAPRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 IWIPYCIKLTSNGGTVDEKCFSVDEIVQPDPPIALNWTLLNVSLTGIHADIQVRWEAPRN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 ADIQKGWMVLEYELQYKEVNETKWKMMDPILTTSVPVYSLKVDKEYEVRVRSKQRNSGNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 ADIQKGWMVLEYELQYKEVNETKWKMMDPILTTSVPVYSLKVDKEYEVRVRSKQRNSGNY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 GEFSEVLYVTLPQMSQFTCEEDFYFPWLLIIIFGIFGLTVMLFVFLFSKQQRIKMLILPP
::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 GEFSEVLYVTLPQMSQFTCEEDFYFPWLLIIIFGIFGLTVMLFVFLFSKQQRKEN
250 260 270 280 290
310 320 330 340 350 360
pF1KE2 VPVPKIKGIDPDLLKEGKLEEVNTILAIHDSYKPEFHSDDSWVEFIELDIDEPDEKTEES
>>CCDS3909.1 PRLR gene_id:5618|Hs108|chr5 (622 aa)
initn: 470 init1: 124 opt: 529 Z-score: 559.1 bits: 113.6 E(32554): 8e-25
Smith-Waterman score: 588; 27.3% identity (52.7% similar) in 600 aa overlap (50-578:30-601)
20 30 40 50 60 70
pF1KE2 SGSEATAAILSRAPWSLQSVNPGLKTNSSKEPKFTKCRSPERETFSCHWTDEVHHGTKNL
.:.. :::::..:::.: : . ::
CCDS39 MKENVASATVFTLLLFLNTCLLNGQLPPGKPEIFKCRSPNKETFTCWW----RPGTD--
10 20 30 40 50
80 90 100 110 120 130
pF1KE2 GPIQLFYTRRNTQEWTQEWKECPDYVSAGENSCYFNSSFTSIWIPYC--IKLTSNGGTV-
: . :. .: .:::::...: :::.:....::.: : .. :.. :.
CCDS39 GGLPTNYSLTYHREGETLMHECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSF
60 70 80 90 100 110
140 150 160 170 180 190
pF1KE2 -DEKCFSVDEIVQPDPPIALNWTLLNVSLTGIHADIQVRWEAPRNADIQKGWMVLEYELQ
:: .: :::::::. : . . . . ..: : :.. ::..: ::..
CCDS39 SDELYVDVTYIVQPDPPLELAVEVKQPEDRKPY--LWIKWSPPTLIDLKTGWFTLLYEIR
120 130 140 150 160 170
200 210 220 230 240 250
pF1KE2 YKEVNETKWKMMDPILTTSVPVYSLKVDKEYEVRVRSKQRNSGNYGEFSEVLYVTLPQMS
: . ..:.. : . ::. ..: :.:: : . : .. .: . .. .: :
CCDS39 LKPEKAAEWEIHFAGQQTEFKILSLHPGQKYLVQVRCKP-DHGYWSAWSPATFIQIP--S
180 190 200 210 220
260 270 280 290 300 310
pF1KE2 QFTCEEDFYFPWLLIIIFG-IFGLTVMLFVFLFSKQQRIKMLILPPVPVPKIKGIDPDLL
.:: .. :. . ... .. : .. : : : . :.:::: :::::.: ::
CCDS39 DFTMNDTTV--WISVAVLSAVICLIIVWAVAL--KGYSMVTCIFPPVPGPKIKGFDAHLL
230 240 250 260 270 280
320 330 340 350 360 370
pF1KE2 KEGKLEEVNTILAIHDSYKPEFHSDDSWVEFIELDIDEPDEKTEESDTDRLLSSDHEKSH
..:: ::. . :. .: . : .: ::..:.: .: :. : : : : :
CCDS39 EKGKSEELLSALGCQD-FPPTSDYEDLLVEYLEVDDSE----------DQHLMSVHSKEH
290 300 310 320 330
380 390 400 410
pF1KE2 SNLGVK------DGDSGRTSCCEPDIL-----ETDFNANDIHEG----------TSEVAQ
. :.: : :::: :: :..: : . : . ... :... .
CCDS39 PSQGMKPTYLDPDTDSGRGSCDSPSLLSEKCEEPQANPSTFYDPEVIEKPENPETTHTWD
340 350 360 370 380 390
420 430 440 450
pF1KE2 PQ--RLKGEADLL------C----LDQKNQNN--SPYH---DAC-----PATQQPSVIQA
:: ..:. . : : : .:.: : :: :.: :: :...
CCDS39 PQCISMEGKIPYFHAGGSKCSTWPLPQPSQHNPRSSYHNITDVCELAVGPAGA-PATLLN
400 410 420 430 440 450
460 470 480
pF1KE2 EKNKP-----QPLPT--EG-------AESTHQAAHI-------QLSNP-SSLSNIDFYAQ
: .: : . . :: .:: :. . : ..: .: . .: :..
CCDS39 EAGKDALKSSQTIKSREEGKATQQREVESFHSETDQDTPWLLPQEKTPFGSAKPLD-YVE
460 470 480 490 500 510
490 500 510 520 530 540
pF1KE2 VSDITPAGSVVLSPGQKNKAGMSQCDMHPEMVS-LCQENFLMDNAYFCEADAKKCIPVAP
. .. :.. : : :....: . :: . . . .::: . . . ::
CCDS39 IHKVNKDGALSLLPKQRENSGKPKKPGTPENNKEYAKVSGVMDNNILVLVPDPHAKNVAC
520 530 540 550 560 570
550 560 570 580 590 600
pF1KE2 HIKVESHIQPSLNQEDIYITTESLTTAAGRPGTGEHVPGSEMPVPDYTSIHIVQSPQGLI
. .. :::.:.. . ..:.....
CCDS39 FEESAKEAPPSLEQNQAEKALANFTATSSKCRLQLGGLDYLDPACFTHSFH
580 590 600 610 620
>>CCDS56362.1 PRLR gene_id:5618|Hs108|chr5 (349 aa)
initn: 434 init1: 124 opt: 523 Z-score: 556.9 bits: 112.4 E(32554): 1.1e-24
Smith-Waterman score: 523; 30.5% identity (58.3% similar) in 331 aa overlap (50-375:30-343)
20 30 40 50 60 70
pF1KE2 SGSEATAAILSRAPWSLQSVNPGLKTNSSKEPKFTKCRSPERETFSCHWTDEVHHGTKNL
.:.. :::::..:::.: : ::
CCDS56 MKENVASATVFTLLLFLNTCLLNGQLPPGKPEIFKCRSPNKETFTCWWRP----GTD--
10 20 30 40 50
80 90 100 110 120 130
pF1KE2 GPIQLFYTRRNTQEWTQEWKECPDYVSAGENSCYFNSSFTSIWIPYC--IKLTSNGGTV-
: . :. .: .:::::...: :::.:....::.: : .. :.. :.
CCDS56 GGLPTNYSLTYHREGETLMHECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSF
60 70 80 90 100 110
140 150 160 170 180 190
pF1KE2 -DEKCFSVDEIVQPDPPIALNWTLLNVSLTGIHADIQVRWEAPRNADIQKGWMVLEYELQ
:: .: :::::::. : . . . . ..: : :.. ::..: ::..
CCDS56 SDELYVDVTYIVQPDPPLELAVEVKQPEDRKPY--LWIKWSPPTLIDLKTGWFTLLYEIR
120 130 140 150 160 170
200 210 220 230 240 250
pF1KE2 YKEVNETKWKMMDPILTTSVPVYSLKVDKEYEVRVRSKQRNSGNYGEFSEVLYVTLPQMS
: . ..:.. : . ::. ..: :.:: : . : .. .: . .. .: :
CCDS56 LKPEKAAEWEIHFAGQQTEFKILSLHPGQKYLVQVRCKP-DHGYWSAWSPATFIQIP--S
180 190 200 210 220
260 270 280 290 300 310
pF1KE2 QFTCEEDFYFPWLLIIIFG-IFGLTVMLFVFLFSKQQRIKMLILPPVPVPKIKGIDPDLL
.:: .. :. . ... .. : .. : : : . :.:::: :::::.: ::
CCDS56 DFTMNDTTV--WISVAVLSAVICLIIVWAVAL--KGYSMVTCIFPPVPGPKIKGFDAHLL
230 240 250 260 270 280
320 330 340 350 360 370
pF1KE2 KEGKLEEVNTILAIHDSYKPEFHSDDSWVEFIELDIDEPDEKTEESDTDRLLSSDHEKSH
..:: ::. . :. .: . : .: ::..:.: : :.. . . :...:. .
CCDS56 EKGKSEELLSALGCQD-FPPTSDYEDLLVEYLEVD-DSEDQHLMSVHSKEHPSQEREQRQ
290 300 310 320 330 340
380 390 400 410 420 430
pF1KE2 SNLGVKDGDSGRTSCCEPDILETDFNANDIHEGTSEVAQPQRLKGEADLLCLDQKNQNNS
.
CCDS56 AQEARDS
>>CCDS56361.1 PRLR gene_id:5618|Hs108|chr5 (376 aa)
initn: 434 init1: 124 opt: 523 Z-score: 556.3 bits: 112.4 E(32554): 1.1e-24
Smith-Waterman score: 528; 31.4% identity (56.9% similar) in 334 aa overlap (50-378:30-337)
20 30 40 50 60 70
pF1KE2 SGSEATAAILSRAPWSLQSVNPGLKTNSSKEPKFTKCRSPERETFSCHWTDEVHHGTKNL
.:.. :::::..:::.: : ::
CCDS56 MKENVASATVFTLLLFLNTCLLNGQLPPGKPEIFKCRSPNKETFTCWWRP----GTD--
10 20 30 40 50
80 90 100 110 120 130
pF1KE2 GPIQLFYTRRNTQEWTQEWKECPDYVSAGENSCYFNSSFTSIWIPYC--IKLTSNGGTV-
: . :. .: .:::::...: :::.:....::.: : .. :.. :.
CCDS56 GGLPTNYSLTYHREGETLMHECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSF
60 70 80 90 100 110
140 150 160 170 180 190
pF1KE2 -DEKCFSVDEIVQPDPPIALNWTLLNVSLTGIHADIQVRWEAPRNADIQKGWMVLEYELQ
:: .: :::::::. : . . . . ..: : :.. ::..: ::..
CCDS56 SDELYVDVTYIVQPDPPLELAVEVKQPEDRKPY--LWIKWSPPTLIDLKTGWFTLLYEIR
120 130 140 150 160 170
200 210 220 230 240 250
pF1KE2 YKEVNETKWKMMDPILTTSVPVYSLKVDKEYEVRVRSKQRNSGNYGEFSEVLYVTLPQMS
: . ..:.. : . ::. ..: :.:: : . : .. .: . .. .: :
CCDS56 LKPEKAAEWEIHFAGQQTEFKILSLHPGQKYLVQVRCKP-DHGYWSAWSPATFIQIP--S
180 190 200 210 220
260 270 280 290 300 310
pF1KE2 QFTCEEDFYFPWLLIIIFG-IFGLTVMLFVFLFSKQQRIKMLILPPVPVPKIKGIDPDLL
.:: .. :. . ... .. : .. : : : . :.:::: :::::.: ::
CCDS56 DFTMNDTTV--WISVAVLSAVICLIIVWAVAL--KGYSMVTCIFPPVPGPKIKGFDAHLL
230 240 250 260 270 280
320 330 340 350 360 370
pF1KE2 KEGKLEEVNTILAIHDSYKPEFHSDDSWVEFIELDIDEPDEKTEESDTDRLLSSDHEKSH
..:: ::. . :. .: . : .: ::..:.: .: :. : : : : :
CCDS56 EKGKSEELLSALGCQD-FPPTSDYEDLLVEYLEVDDSE----------DQHLMSVHSKEH
290 300 310 320 330
380 390 400 410 420 430
pF1KE2 SNLGVKDGDSGRTSCCEPDILETDFNANDIHEGTSEVAQPQRLKGEADLLCLDQKNQNNS
. :
CCDS56 PSQGDPLMLGASHYKNLKSYRPRKISSQGRLAVFTKATLTTVQ
340 350 360 370
>>CCDS56360.1 PRLR gene_id:5618|Hs108|chr5 (288 aa)
initn: 400 init1: 124 opt: 451 Z-score: 482.2 bits: 98.3 E(32554): 1.5e-20
Smith-Waterman score: 451; 31.4% identity (58.3% similar) in 271 aa overlap (50-315:30-285)
20 30 40 50 60 70
pF1KE2 SGSEATAAILSRAPWSLQSVNPGLKTNSSKEPKFTKCRSPERETFSCHWTDEVHHGTKNL
.:.. :::::..:::.: : . ::
CCDS56 MKENVASATVFTLLLFLNTCLLNGQLPPGKPEIFKCRSPNKETFTCWW----RPGTD--
10 20 30 40 50
80 90 100 110 120 130
pF1KE2 GPIQLFYTRRNTQEWTQEWKECPDYVSAGENSCYFNSSFTSIWIPYC--IKLTSNGGTV-
: . :. .: .:::::...: :::.:....::.: : .. :.. :.
CCDS56 GGLPTNYSLTYHREGETLMHECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSF
60 70 80 90 100 110
140 150 160 170 180 190
pF1KE2 -DEKCFSVDEIVQPDPPIALNWTLLNVSLTGIHADIQVRWEAPRNADIQKGWMVLEYELQ
:: .: :::::::. : . . . . ..: : :.. ::..: ::..
CCDS56 SDELYVDVTYIVQPDPPLELAVEVKQPEDRKPY--LWIKWSPPTLIDLKTGWFTLLYEIR
120 130 140 150 160 170
200 210 220 230 240 250
pF1KE2 YKEVNETKWKMMDPILTTSVPVYSLKVDKEYEVRVRSKQRNSGNYGEFSEVLYVTLPQMS
: . ..:.. : . ::. ..: :.:: : . : .. .: . .. .: :
CCDS56 LKPEKAAEWEIHFAGQQTEFKILSLHPGQKYLVQVRCKP-DHGYWSAWSPATFIQIP--S
180 190 200 210 220
260 270 280 290 300 310
pF1KE2 QFTCEEDFYFPWLLIIIFG-IFGLTVMLFVFLFSKQQRIKMLILPPVPVPKIKGIDPDLL
.:: .. :. . ... .. : .. : : : . :.:::: :::::.: ::
CCDS56 DFTMNDTTV--WISVAVLSAVICLIIVWAVAL--KGYSMVTCIFPPVPGPKIKGFDAHLL
230 240 250 260 270 280
320 330 340 350 360 370
pF1KE2 KEGKLEEVNTILAIHDSYKPEFHSDDSWVEFIELDIDEPDEKTEESDTDRLLSSDHEKSH
.
CCDS56 EVTP
>>CCDS56359.1 PRLR gene_id:5618|Hs108|chr5 (268 aa)
initn: 331 init1: 124 opt: 370 Z-score: 397.2 bits: 82.5 E(32554): 8.3e-16
Smith-Waterman score: 370; 30.9% identity (58.0% similar) in 207 aa overlap (50-252:30-227)
20 30 40 50 60 70
pF1KE2 SGSEATAAILSRAPWSLQSVNPGLKTNSSKEPKFTKCRSPERETFSCHWTDEVHHGTKNL
.:.. :::::..:::.: : ::
CCDS56 MKENVASATVFTLLLFLNTCLLNGQLPPGKPEIFKCRSPNKETFTCWWRP----GTD--
10 20 30 40 50
80 90 100 110 120 130
pF1KE2 GPIQLFYTRRNTQEWTQEWKECPDYVSAGENSCYFNSSFTSIWIPYC--IKLTSNGGTV-
: . :. .: .:::::...: :::.:....::.: : .. :.. :.
CCDS56 GGLPTNYSLTYHREGETLMHECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSF
60 70 80 90 100 110
140 150 160 170 180 190
pF1KE2 -DEKCFSVDEIVQPDPPIALNWTLLNVSLTGIHADIQVRWEAPRNADIQKGWMVLEYELQ
:: .: :::::::. : . . . . ..: : :.. ::..: ::..
CCDS56 SDELYVDVTYIVQPDPPLELAVEVKQPEDRKPY--LWIKWSPPTLIDLKTGWFTLLYEIR
120 130 140 150 160 170
200 210 220 230 240 250
pF1KE2 YKEVNETKWKMMDPILTTSVPVYSLKVDKEYEVRVRSKQRNSGNYGEFSEVLYVTLPQMS
: . ..:.. : . ::. ..: :.:: : . : .. .: . .. .:
CCDS56 LKPEKAAEWEIHFAGQQTEFKILSLHPGQKYLVQVRCKP-DHGYWSAWSPATFIQIPSGD
180 190 200 210 220 230
260 270 280 290 300 310
pF1KE2 QFTCEEDFYFPWLLIIIFGIFGLTVMLFVFLFSKQQRIKMLILPPVPVPKIKGIDPDLLK
CCDS56 PLMLGASHYKNLKSYRPRKISSQGRLAVFTKATLTTVQ
240 250 260
>>CCDS56358.1 PRLR gene_id:5618|Hs108|chr5 (521 aa)
initn: 270 init1: 117 opt: 354 Z-score: 375.7 bits: 79.4 E(32554): 1.3e-14
Smith-Waterman score: 384; 25.7% identity (50.9% similar) in 499 aa overlap (147-578:24-500)
120 130 140 150 160 170
pF1KE2 SFTSIWIPYCIKLTSNGGTVDEKCFSVDEIVQPDPPIALNWTLLNVSLTGIHADIQVRWE
::::::. : . . . . ..:
CCDS56 MKENVASATVFTLLLFLNTCLLNVQPDPPLELAVEVKQPEDRKPY--LWIKWS
10 20 30 40 50
180 190 200 210 220 230
pF1KE2 APRNADIQKGWMVLEYELQYKEVNETKWKMMDPILTTSVPVYSLKVDKEYEVRVRSKQRN
: :.. ::..: ::.. : . ..:.. : . ::. ..: :.:: : .
CCDS56 PPTLIDLKTGWFTLLYEIRLKPEKAAEWEIHFAGQQTEFKILSLHPGQKYLVQVRCKP-D
60 70 80 90 100 110
240 250 260 270 280 290
pF1KE2 SGNYGEFSEVLYVTLPQMSQFTCEEDFYFPWLLIIIFG-IFGLTVMLFVFLFSKQQRIKM
: .. .: . .. .: :.:: .. :. . ... .. : .. : : : .
CCDS56 HGYWSAWSPATFIQIP--SDFTMNDTTV--WISVAVLSAVICLIIVWAVAL--KGYSMVT
120 130 140 150 160
300 310 320 330 340 350
pF1KE2 LILPPVPVPKIKGIDPDLLKEGKLEEVNTILAIHDSYKPEFHSDDSWVEFIELDIDEPDE
:.:::: :::::.: ::..:: ::. . :. .: . : .: ::..:.: .:
CCDS56 CIFPPVPGPKIKGFDAHLLEKGKSEELLSALGCQD-FPPTSDYEDLLVEYLEVDDSE---
170 180 190 200 210 220
360 370 380 390 400
pF1KE2 KTEESDTDRLLSSDHEKSHSNLGVK------DGDSGRTSCCEPDIL-----ETDFNANDI
:. : : : : : . :.: : :::: :: :..: : . : . .
CCDS56 -------DQHLMSVHSKEHPSQGMKPTYLDPDTDSGRGSCDSPSLLSEKCEEPQANPSTF
230 240 250 260 270
410 420 430
pF1KE2 HEG----------TSEVAQPQ--RLKGEADLL------C----LDQKNQNN--SPYH---
.. :... .:: ..:. . : : : .:.: : ::
CCDS56 YDPEVIEKPENPETTHTWDPQCISMEGKIPYFHAGGSKCSTWPLPQPSQHNPRSSYHNIT
280 290 300 310 320 330
440 450 460 470
pF1KE2 DAC-----PATQQPSVIQAEKNKP-----QPLPT--EG-------AESTHQAAHI-----
:.: :: :... : .: : . . :: .:: :. .
CCDS56 DVCELAVGPAGA-PATLLNEAGKDALKSSQTIKSREEGKATQQREVESFHSETDQDTPWL
340 350 360 370 380 390
480 490 500 510 520
pF1KE2 --QLSNP-SSLSNIDFYAQVSDITPAGSVVLSPGQKNKAGMSQCDMHPEMVS-LCQENFL
: ..: .: . .: :... .. :.. : : :....: . :: . . . .
CCDS56 LPQEKTPFGSAKPLD-YVEIHKVNKDGALSLLPKQRENSGKPKKPGTPENNKEYAKVSGV
400 410 420 430 440 450
530 540 550 560 570 580
pF1KE2 MDNAYFCEADAKKCIPVAPHIKVESHIQPSLNQEDIYITTESLTTAAGRPGTGEHVPGSE
::: . . . :: . .. :::.:.. . ..:.....
CCDS56 MDNNILVLVPDPHAKNVACFEESAKEAPPSLEQNQAEKALANFTATSSKCRLQLGGLDYL
460 470 480 490 500 510
590 600 610 620 630
pF1KE2 MPVPDYTSIHIVQSPQGLILNATALPLPDKEFLSSCGYVSTDQLNKIMP
CCDS56 DPACFTHSFH
520
638 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 16 14:59:08 2016 done: Wed Nov 16 14:59:08 2016
Total Scan time: 3.400 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]