Result of FASTA (omim) for
pFN21AE2642
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2642, 397 aa
1>>>pF1KE2642 397 - 397 aa - 397 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.1595+/-0.000384; mu= 13.0329+/- 0.024
mean_var=95.0129+/-17.974, 0's: 0 Z-trim(113.8): 84 B-trim: 50 in 2/54
Lambda= 0.131578
statistics sampled from 23263 (23348) to 23263 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.653), E-opt: 0.2 (0.274), width: 16
Scan time: 7.450
The best scores are: opt bits E(85289)
NP_001003828 (OMIM: 608121) beta-parvin isoform a ( 397) 2597 503.5 3.7e-142
NP_037459 (OMIM: 608121) beta-parvin isoform b [Ho ( 364) 2102 409.5 6.6e-114
NP_001230314 (OMIM: 608121) beta-parvin isoform c ( 327) 2098 408.7 1e-113
XP_005261653 (OMIM: 608121) PREDICTED: beta-parvin ( 312) 2007 391.4 1.6e-108
XP_005253072 (OMIM: 608120) PREDICTED: alpha-parvi ( 328) 1612 316.4 6.1e-86
NP_060692 (OMIM: 608120) alpha-parvin [Homo sapien ( 412) 1612 316.5 7.3e-86
XP_016884281 (OMIM: 608121) PREDICTED: beta-parvin ( 341) 1420 280.0 5.9e-75
NP_001230315 (OMIM: 608121) beta-parvin isoform d ( 289) 1325 261.9 1.4e-69
XP_005261759 (OMIM: 608122) PREDICTED: gamma-parvi ( 331) 863 174.3 3.9e-43
NP_001131077 (OMIM: 608122) gamma-parvin [Homo sap ( 331) 863 174.3 3.9e-43
NP_071424 (OMIM: 608122) gamma-parvin [Homo sapien ( 331) 863 174.3 3.9e-43
XP_011528604 (OMIM: 608122) PREDICTED: gamma-parvi ( 398) 863 174.3 4.5e-43
XP_016884397 (OMIM: 608122) PREDICTED: gamma-parvi ( 317) 777 157.9 3.1e-38
XP_016884396 (OMIM: 608122) PREDICTED: gamma-parvi ( 317) 777 157.9 3.1e-38
>>NP_001003828 (OMIM: 608121) beta-parvin isoform a [Hom (397 aa)
initn: 2597 init1: 2597 opt: 2597 Z-score: 2673.2 bits: 503.5 E(85289): 3.7e-142
Smith-Waterman score: 2597; 99.7% identity (100.0% similar) in 397 aa overlap (1-397:1-397)
10 20 30 40 50 60
pF1KE2 MHHVFKDHQRGEKRGFLSPENKNCRRLELRRGCSCSWGLCSQALMASLAGSLLPGSDRSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MHHVFKDHQRGEKRGFLSPENKNCRRLELRRGCSCSWGLCSQALMASLAGSLLPGSDRSG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 VETSEYAQGGVSDLQEEGKNAINSPMSPALADVHPEDTQLEENEERTMIDPTSKEDPKFK
::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::
NP_001 VETSEYAQGGVSDLQEEGKNAINSPMSPALVDVHPEDTQLEENEERTMIDPTSKEDPKFK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 ELVKVLLDWINDVLVEERIIVKQLEEDLYDGQVLQKLLEKLAGCKLNVAEVTQSEIGQKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELVKVLLDWINDVLVEERIIVKQLEEDLYDGQVLQKLLEKLAGCKLNVAEVTQSEIGQKQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 KLQTVLEAVHDLLRPRGWALRWSVDSIHGKNLVAILHLLVSLAMHFRAPIRLPEHVTVQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLQTVLEAVHDLLRPRGWALRWSVDSIHGKNLVAILHLLVSLAMHFRAPIRLPEHVTVQV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 VVVRKREGLLHSSHISEELTTTTEMMMGRFERDAFDTLFDHAPDKLSVVKKSLITFVNKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVVRKREGLLHSSHISEELTTTTEMMMGRFERDAFDTLFDHAPDKLSVVKKSLITFVNKH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 LNKLNLEVTELETQFADGVYLVLLMGLLEDYFVPLHHFYLTPESFDQKVHNVSFAFELML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNKLNLEVTELETQFADGVYLVLLMGLLEDYFVPLHHFYLTPESFDQKVHNVSFAFELML
310 320 330 340 350 360
370 380 390
pF1KE2 DGGLKKPKARPEDVVNLDLKSTLRVLYNLFTKYKNVE
:::::::::::::::::::::::::::::::::::::
NP_001 DGGLKKPKARPEDVVNLDLKSTLRVLYNLFTKYKNVE
370 380 390
>>NP_037459 (OMIM: 608121) beta-parvin isoform b [Homo s (364 aa)
initn: 2102 init1: 2102 opt: 2102 Z-score: 2165.9 bits: 409.5 E(85289): 6.6e-114
Smith-Waterman score: 2102; 99.7% identity (100.0% similar) in 327 aa overlap (71-397:38-364)
50 60 70 80 90 100
pF1KE2 SQALMASLAGSLLPGSDRSGVETSEYAQGGVSDLQEEGKNAINSPMSPALADVHPEDTQL
::::::::::::::::::::.:::::::::
NP_037 PTPRPRRMKKDESFLGKLGGTLARKRRAREVSDLQEEGKNAINSPMSPALVDVHPEDTQL
10 20 30 40 50 60
110 120 130 140 150 160
pF1KE2 EENEERTMIDPTSKEDPKFKELVKVLLDWINDVLVEERIIVKQLEEDLYDGQVLQKLLEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 EENEERTMIDPTSKEDPKFKELVKVLLDWINDVLVEERIIVKQLEEDLYDGQVLQKLLEK
70 80 90 100 110 120
170 180 190 200 210 220
pF1KE2 LAGCKLNVAEVTQSEIGQKQKLQTVLEAVHDLLRPRGWALRWSVDSIHGKNLVAILHLLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 LAGCKLNVAEVTQSEIGQKQKLQTVLEAVHDLLRPRGWALRWSVDSIHGKNLVAILHLLV
130 140 150 160 170 180
230 240 250 260 270 280
pF1KE2 SLAMHFRAPIRLPEHVTVQVVVVRKREGLLHSSHISEELTTTTEMMMGRFERDAFDTLFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 SLAMHFRAPIRLPEHVTVQVVVVRKREGLLHSSHISEELTTTTEMMMGRFERDAFDTLFD
190 200 210 220 230 240
290 300 310 320 330 340
pF1KE2 HAPDKLSVVKKSLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEDYFVPLHHFYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 HAPDKLSVVKKSLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEDYFVPLHHFYL
250 260 270 280 290 300
350 360 370 380 390
pF1KE2 TPESFDQKVHNVSFAFELMLDGGLKKPKARPEDVVNLDLKSTLRVLYNLFTKYKNVE
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 TPESFDQKVHNVSFAFELMLDGGLKKPKARPEDVVNLDLKSTLRVLYNLFTKYKNVE
310 320 330 340 350 360
>>NP_001230314 (OMIM: 608121) beta-parvin isoform c [Hom (327 aa)
initn: 2098 init1: 2098 opt: 2098 Z-score: 2162.5 bits: 408.7 E(85289): 1e-113
Smith-Waterman score: 2098; 99.4% identity (100.0% similar) in 327 aa overlap (71-397:1-327)
50 60 70 80 90 100
pF1KE2 SQALMASLAGSLLPGSDRSGVETSEYAQGGVSDLQEEGKNAINSPMSPALADVHPEDTQL
.:::::::::::::::::::.:::::::::
NP_001 MSDLQEEGKNAINSPMSPALVDVHPEDTQL
10 20 30
110 120 130 140 150 160
pF1KE2 EENEERTMIDPTSKEDPKFKELVKVLLDWINDVLVEERIIVKQLEEDLYDGQVLQKLLEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EENEERTMIDPTSKEDPKFKELVKVLLDWINDVLVEERIIVKQLEEDLYDGQVLQKLLEK
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE2 LAGCKLNVAEVTQSEIGQKQKLQTVLEAVHDLLRPRGWALRWSVDSIHGKNLVAILHLLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAGCKLNVAEVTQSEIGQKQKLQTVLEAVHDLLRPRGWALRWSVDSIHGKNLVAILHLLV
100 110 120 130 140 150
230 240 250 260 270 280
pF1KE2 SLAMHFRAPIRLPEHVTVQVVVVRKREGLLHSSHISEELTTTTEMMMGRFERDAFDTLFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLAMHFRAPIRLPEHVTVQVVVVRKREGLLHSSHISEELTTTTEMMMGRFERDAFDTLFD
160 170 180 190 200 210
290 300 310 320 330 340
pF1KE2 HAPDKLSVVKKSLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEDYFVPLHHFYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HAPDKLSVVKKSLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEDYFVPLHHFYL
220 230 240 250 260 270
350 360 370 380 390
pF1KE2 TPESFDQKVHNVSFAFELMLDGGLKKPKARPEDVVNLDLKSTLRVLYNLFTKYKNVE
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPESFDQKVHNVSFAFELMLDGGLKKPKARPEDVVNLDLKSTLRVLYNLFTKYKNVE
280 290 300 310 320
>>XP_005261653 (OMIM: 608121) PREDICTED: beta-parvin iso (312 aa)
initn: 2007 init1: 2007 opt: 2007 Z-score: 2069.4 bits: 391.4 E(85289): 1.6e-108
Smith-Waterman score: 2007; 99.7% identity (100.0% similar) in 312 aa overlap (86-397:1-312)
60 70 80 90 100 110
pF1KE2 SDRSGVETSEYAQGGVSDLQEEGKNAINSPMSPALADVHPEDTQLEENEERTMIDPTSKE
:::::.::::::::::::::::::::::::
XP_005 MSPALVDVHPEDTQLEENEERTMIDPTSKE
10 20 30
120 130 140 150 160 170
pF1KE2 DPKFKELVKVLLDWINDVLVEERIIVKQLEEDLYDGQVLQKLLEKLAGCKLNVAEVTQSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DPKFKELVKVLLDWINDVLVEERIIVKQLEEDLYDGQVLQKLLEKLAGCKLNVAEVTQSE
40 50 60 70 80 90
180 190 200 210 220 230
pF1KE2 IGQKQKLQTVLEAVHDLLRPRGWALRWSVDSIHGKNLVAILHLLVSLAMHFRAPIRLPEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IGQKQKLQTVLEAVHDLLRPRGWALRWSVDSIHGKNLVAILHLLVSLAMHFRAPIRLPEH
100 110 120 130 140 150
240 250 260 270 280 290
pF1KE2 VTVQVVVVRKREGLLHSSHISEELTTTTEMMMGRFERDAFDTLFDHAPDKLSVVKKSLIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VTVQVVVVRKREGLLHSSHISEELTTTTEMMMGRFERDAFDTLFDHAPDKLSVVKKSLIT
160 170 180 190 200 210
300 310 320 330 340 350
pF1KE2 FVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEDYFVPLHHFYLTPESFDQKVHNVSFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEDYFVPLHHFYLTPESFDQKVHNVSFA
220 230 240 250 260 270
360 370 380 390
pF1KE2 FELMLDGGLKKPKARPEDVVNLDLKSTLRVLYNLFTKYKNVE
::::::::::::::::::::::::::::::::::::::::::
XP_005 FELMLDGGLKKPKARPEDVVNLDLKSTLRVLYNLFTKYKNVE
280 290 300 310
>>XP_005253072 (OMIM: 608120) PREDICTED: alpha-parvin is (328 aa)
initn: 1611 init1: 1611 opt: 1612 Z-score: 1663.9 bits: 316.4 E(85289): 6.1e-86
Smith-Waterman score: 1612; 76.0% identity (91.2% similar) in 329 aa overlap (71-397:2-328)
50 60 70 80 90 100
pF1KE2 SQALMASLAGSLLPGSDRSGVETSEYAQGGVSDLQEEGKNAINSPMSPALADVHPEDTQL
::.::::: :::: :.:: .. ::::.:
XP_005 MVSELQEEGMNAINLPLSPIPFELDPEDTML
10 20 30
110 120 130 140 150 160
pF1KE2 EENEERTMIDPTSKEDPKFKELVKVLLDWINDVLVEERIIVKQLEEDLYDGQVLQKLLEK
:::: :::.::.:. :::..::.:::.:::::::: ::::::.: ::::::::::::.::
XP_005 EENEVRTMVDPNSRSDPKLQELMKVLIDWINDVLVGERIIVKDLAEDLYDGQVLQKLFEK
40 50 60 70 80 90
170 180 190 200 210
pF1KE2 LAGCKLNVAEVTQSEIGQKQKLQTVLEAVHDLLR--PRGWALRWSVDSIHGKNLVAILHL
: . ::::::::::::.:::::::::: ... :. :: ...:.:::.:.:.:::::::
XP_005 LESEKLNVAEVTQSEIAQKQKLQTVLEKINETLKLPPR--SIKWNVDSVHAKSLVAILHL
100 110 120 130 140
220 230 240 250 260 270
pF1KE2 LVSLAMHFRAPIRLPEHVTVQVVVVRKREGLLHSSHISEELTTTTEMMMGRFERDAFDTL
::.:...::::::::.::..:::::.::::.:.: .:.::.: .:: . :: ::::::::
XP_005 LVALSQYFRAPIRLPDHVSIQVVVVQKREGILQSRQIQEEITGNTEALSGRHERDAFDTL
150 160 170 180 190 200
280 290 300 310 320 330
pF1KE2 FDHAPDKLSVVKKSLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEDYFVPLHHF
::::::::.::::.::::::::::::::::::::::::::::::::::::: :::::: :
XP_005 FDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSF
210 220 230 240 250 260
340 350 360 370 380 390
pF1KE2 YLTPESFDQKVHNVSFAFELMLDGGLKKPKARPEDVVNLDLKSTLRVLYNLFTKYKNVE
.:::.::.::: ::::::::: ::::.::: ::::.:: ::::::::::::::::.:::
XP_005 FLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTKYRNVE
270 280 290 300 310 320
>>NP_060692 (OMIM: 608120) alpha-parvin [Homo sapiens] (412 aa)
initn: 1611 init1: 1611 opt: 1612 Z-score: 1662.4 bits: 316.5 E(85289): 7.3e-86
Smith-Waterman score: 1612; 76.0% identity (91.2% similar) in 329 aa overlap (71-397:86-412)
50 60 70 80 90 100
pF1KE2 SQALMASLAGSLLPGSDRSGVETSEYAQGGVSDLQEEGKNAINSPMSPALADVHPEDTQL
::.::::: :::: :.:: .. ::::.:
NP_060 TPKSPPSRKKDDSFLGKLGGTLARRKKAKEVSELQEEGMNAINLPLSPIPFELDPEDTML
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE2 EENEERTMIDPTSKEDPKFKELVKVLLDWINDVLVEERIIVKQLEEDLYDGQVLQKLLEK
:::: :::.::.:. :::..::.:::.:::::::: ::::::.: ::::::::::::.::
NP_060 EENEVRTMVDPNSRSDPKLQELMKVLIDWINDVLVGERIIVKDLAEDLYDGQVLQKLFEK
120 130 140 150 160 170
170 180 190 200 210
pF1KE2 LAGCKLNVAEVTQSEIGQKQKLQTVLEAVHDLLR--PRGWALRWSVDSIHGKNLVAILHL
: . ::::::::::::.:::::::::: ... :. :: ...:.:::.:.:.:::::::
NP_060 LESEKLNVAEVTQSEIAQKQKLQTVLEKINETLKLPPR--SIKWNVDSVHAKSLVAILHL
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE2 LVSLAMHFRAPIRLPEHVTVQVVVVRKREGLLHSSHISEELTTTTEMMMGRFERDAFDTL
::.:...::::::::.::..:::::.::::.:.: .:.::.: .:: . :: ::::::::
NP_060 LVALSQYFRAPIRLPDHVSIQVVVVQKREGILQSRQIQEEITGNTEALSGRHERDAFDTL
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE2 FDHAPDKLSVVKKSLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEDYFVPLHHF
::::::::.::::.::::::::::::::::::::::::::::::::::::: :::::: :
NP_060 FDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSF
300 310 320 330 340 350
340 350 360 370 380 390
pF1KE2 YLTPESFDQKVHNVSFAFELMLDGGLKKPKARPEDVVNLDLKSTLRVLYNLFTKYKNVE
.:::.::.::: ::::::::: ::::.::: ::::.:: ::::::::::::::::.:::
NP_060 FLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTKYRNVE
360 370 380 390 400 410
>>XP_016884281 (OMIM: 608121) PREDICTED: beta-parvin iso (341 aa)
initn: 1420 init1: 1420 opt: 1420 Z-score: 1466.7 bits: 280.0 E(85289): 5.9e-75
Smith-Waterman score: 1910; 92.7% identity (93.0% similar) in 327 aa overlap (71-397:38-341)
50 60 70 80 90 100
pF1KE2 SQALMASLAGSLLPGSDRSGVETSEYAQGGVSDLQEEGKNAINSPMSPALADVHPEDTQL
::::::::::::::::::::.:::::::::
XP_016 PTPRPRRMKKDESFLGKLGGTLARKRRAREVSDLQEEGKNAINSPMSPALVDVHPEDTQL
10 20 30 40 50 60
110 120 130 140 150 160
pF1KE2 EENEERTMIDPTSKEDPKFKELVKVLLDWINDVLVEERIIVKQLEEDLYDGQVLQKLLEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EENEERTMIDPTSKEDPKFKELVKVLLDWINDVLVEERIIVKQLEEDLYDGQVLQKLLEK
70 80 90 100 110 120
170 180 190 200 210 220
pF1KE2 LAGCKLNVAEVTQSEIGQKQKLQTVLEAVHDLLRPRGWALRWSVDSIHGKNLVAILHLLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAGCKLNVAEVTQSEIGQKQKLQTVLEAVHDLLRPRGWALRWSVDSIHGKNLVAILHLLV
130 140 150 160 170 180
230 240 250 260 270 280
pF1KE2 SLAMHFRAPIRLPEHVTVQVVVVRKREGLLHSSHISEELTTTTEMMMGRFERDAFDTLFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLAMHFRAPIRLPEHVTVQVVVVRKREGLLHSSHISEELTTTTEMMMGRFERDAFDTLFD
190 200 210 220 230 240
290 300 310 320 330 340
pF1KE2 HAPDKLSVVKKSLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEDYFVPLHHFYL
::::::::::: ::::::::::::::::::::::::::
XP_016 HAPDKLSVVKK-----------------------FADGVYLVLLMGLLEDYFVPLHHFYL
250 260 270 280
350 360 370 380 390
pF1KE2 TPESFDQKVHNVSFAFELMLDGGLKKPKARPEDVVNLDLKSTLRVLYNLFTKYKNVE
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPESFDQKVHNVSFAFELMLDGGLKKPKARPEDVVNLDLKSTLRVLYNLFTKYKNVE
290 300 310 320 330 340
>>NP_001230315 (OMIM: 608121) beta-parvin isoform d [Hom (289 aa)
initn: 1325 init1: 1325 opt: 1325 Z-score: 1370.3 bits: 261.9 E(85289): 1.4e-69
Smith-Waterman score: 1815; 92.3% identity (92.6% similar) in 312 aa overlap (86-397:1-289)
60 70 80 90 100 110
pF1KE2 SDRSGVETSEYAQGGVSDLQEEGKNAINSPMSPALADVHPEDTQLEENEERTMIDPTSKE
:::::.::::::::::::::::::::::::
NP_001 MSPALVDVHPEDTQLEENEERTMIDPTSKE
10 20 30
120 130 140 150 160 170
pF1KE2 DPKFKELVKVLLDWINDVLVEERIIVKQLEEDLYDGQVLQKLLEKLAGCKLNVAEVTQSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPKFKELVKVLLDWINDVLVEERIIVKQLEEDLYDGQVLQKLLEKLAGCKLNVAEVTQSE
40 50 60 70 80 90
180 190 200 210 220 230
pF1KE2 IGQKQKLQTVLEAVHDLLRPRGWALRWSVDSIHGKNLVAILHLLVSLAMHFRAPIRLPEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGQKQKLQTVLEAVHDLLRPRGWALRWSVDSIHGKNLVAILHLLVSLAMHFRAPIRLPEH
100 110 120 130 140 150
240 250 260 270 280 290
pF1KE2 VTVQVVVVRKREGLLHSSHISEELTTTTEMMMGRFERDAFDTLFDHAPDKLSVVKKSLIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTVQVVVVRKREGLLHSSHISEELTTTTEMMMGRFERDAFDTLFDHAPDKLSVVKK----
160 170 180 190 200
300 310 320 330 340 350
pF1KE2 FVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEDYFVPLHHFYLTPESFDQKVHNVSFA
:::::::::::::::::::::::::::::::::::::::::
NP_001 -------------------FADGVYLVLLMGLLEDYFVPLHHFYLTPESFDQKVHNVSFA
210 220 230 240
360 370 380 390
pF1KE2 FELMLDGGLKKPKARPEDVVNLDLKSTLRVLYNLFTKYKNVE
::::::::::::::::::::::::::::::::::::::::::
NP_001 FELMLDGGLKKPKARPEDVVNLDLKSTLRVLYNLFTKYKNVE
250 260 270 280
>>XP_005261759 (OMIM: 608122) PREDICTED: gamma-parvin is (331 aa)
initn: 862 init1: 465 opt: 863 Z-score: 895.4 bits: 174.3 E(85289): 3.9e-43
Smith-Waterman score: 863; 45.2% identity (78.7% similar) in 301 aa overlap (95-393:19-316)
70 80 90 100 110 120
pF1KE2 EYAQGGVSDLQEEGKNAINSPMSPALADVHPEDTQLEENEERTMIDPTSKEDPKFKELVK
: . .: .. .. .. :::..::::.:: :
XP_005 MEPEFLYDLLQLPKGVEPPAEEELSKGGKKKYLPPTSRKDPKFEELQK
10 20 30 40
130 140 150 160 170 180
pF1KE2 VLLDWINDVLVEERIIVKQLEEDLYDGQVLQKLLEKLAGCKLNVAEVTQSEIGQKQKLQT
::..::: .:. :.:.:..::::..:: .:..:...::. ::.. ... . .::.:: .
XP_005 VLMEWINATLLPEHIVVRSLEEDMFDGLILHHLFQRLAALKLEAEDIALTATSQKHKLTV
50 60 70 80 90 100
190 200 210 220 230 240
pF1KE2 VLEAVHDLLRPRGWALRWSVDSIHGKNLVAILHLLVSLAMHFRAPIRLPEHVTVQVVVVR
:::::. :. . : .:::.:: .:.:.. :::::.:: .:. . :: .: :.:....
XP_005 VLEAVNRSLQLEEWQAKWSVESIFNKDLLSTLHLLVALAKRFQPDLSLPTNVQVEVITIE
110 120 130 140 150 160
250 260 270 280 290 300
pF1KE2 KREGLLHSSHISEELTTTTEMMMGRFE--RDAFDTLFDHAPDKLSVVKKSLITFVNKHLN
. .. :.: .. :.:: :. . : .:.:: :: ::.:...::.....:::..:.
XP_005 STKSGLKSEKLVEQLT---EYSTDKDEPPKDVFDELFKLAPEKVNAVKEAIVNFVNQKLD
170 180 190 200 210 220
310 320 330 340 350 360
pF1KE2 KLNLEVTELETQFADGVYLVLLMGLLEDYFVPLHHFYLTPESFDQKVHNVSFAFELMLDG
.:.: : .:.::::::: :.::.: :: .:. :..:::::.: . .:::..:.::. :
XP_005 RLGLSVQNLDTQFADGVILLLLIGQLEGFFLHLKEFYLTPNSPAEMLHNVTLALELLKDE
230 240 250 260 270 280
370 380 390
pF1KE2 GLKKPKARPEDVVNLDLKSTLRVLYNLFTKYKNVE
:: . . :::.:: : ::::::::.:: :.
XP_005 GLLSCPVSPEDIVNKDAKSTLRVLYGLFCKHTQKAHRDRTPHGAPN
290 300 310 320 330
>>NP_001131077 (OMIM: 608122) gamma-parvin [Homo sapiens (331 aa)
initn: 862 init1: 465 opt: 863 Z-score: 895.4 bits: 174.3 E(85289): 3.9e-43
Smith-Waterman score: 863; 45.2% identity (78.7% similar) in 301 aa overlap (95-393:19-316)
70 80 90 100 110 120
pF1KE2 EYAQGGVSDLQEEGKNAINSPMSPALADVHPEDTQLEENEERTMIDPTSKEDPKFKELVK
: . .: .. .. .. :::..::::.:: :
NP_001 MEPEFLYDLLQLPKGVEPPAEEELSKGGKKKYLPPTSRKDPKFEELQK
10 20 30 40
130 140 150 160 170 180
pF1KE2 VLLDWINDVLVEERIIVKQLEEDLYDGQVLQKLLEKLAGCKLNVAEVTQSEIGQKQKLQT
::..::: .:. :.:.:..::::..:: .:..:...::. ::.. ... . .::.:: .
NP_001 VLMEWINATLLPEHIVVRSLEEDMFDGLILHHLFQRLAALKLEAEDIALTATSQKHKLTV
50 60 70 80 90 100
190 200 210 220 230 240
pF1KE2 VLEAVHDLLRPRGWALRWSVDSIHGKNLVAILHLLVSLAMHFRAPIRLPEHVTVQVVVVR
:::::. :. . : .:::.:: .:.:.. :::::.:: .:. . :: .: :.:....
NP_001 VLEAVNRSLQLEEWQAKWSVESIFNKDLLSTLHLLVALAKRFQPDLSLPTNVQVEVITIE
110 120 130 140 150 160
250 260 270 280 290 300
pF1KE2 KREGLLHSSHISEELTTTTEMMMGRFE--RDAFDTLFDHAPDKLSVVKKSLITFVNKHLN
. .. :.: .. :.:: :. . : .:.:: :: ::.:...::.....:::..:.
NP_001 STKSGLKSEKLVEQLT---EYSTDKDEPPKDVFDELFKLAPEKVNAVKEAIVNFVNQKLD
170 180 190 200 210 220
310 320 330 340 350 360
pF1KE2 KLNLEVTELETQFADGVYLVLLMGLLEDYFVPLHHFYLTPESFDQKVHNVSFAFELMLDG
.:.: : .:.::::::: :.::.: :: .:. :..:::::.: . .:::..:.::. :
NP_001 RLGLSVQNLDTQFADGVILLLLIGQLEGFFLHLKEFYLTPNSPAEMLHNVTLALELLKDE
230 240 250 260 270 280
370 380 390
pF1KE2 GLKKPKARPEDVVNLDLKSTLRVLYNLFTKYKNVE
:: . . :::.:: : ::::::::.:: :.
NP_001 GLLSCPVSPEDIVNKDAKSTLRVLYGLFCKHTQKAHRDRTPHGAPN
290 300 310 320 330
397 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 17:43:23 2016 done: Tue Nov 8 17:43:24 2016
Total Scan time: 7.450 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]