Result of FASTA (omim) for
pFN21AE2629
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2629, 950 aa
1>>>pF1KE2629 950 - 950 aa - 950 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6696+/-0.000314; mu= 20.3990+/- 0.020
mean_var=88.1150+/-17.619, 0's: 0 Z-trim(117.7): 16 B-trim: 248 in 1/54
Lambda= 0.136631
statistics sampled from 29895 (29909) to 29895 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.69), E-opt: 0.2 (0.351), width: 16
Scan time: 16.240
The best scores are: opt bits E(85289)
NP_001159694 (OMIM: 613368) carnosine synthase 1 i ( 950) 6487 1289.1 0
XP_011543491 (OMIM: 613368) PREDICTED: carnosine s ( 950) 6487 1289.1 0
XP_016873543 (OMIM: 613368) PREDICTED: carnosine s ( 966) 6480 1287.8 0
XP_016873544 (OMIM: 613368) PREDICTED: carnosine s ( 936) 5607 1115.7 0
NP_065862 (OMIM: 613368) carnosine synthase 1 isof ( 827) 5584 1111.1 0
XP_011543493 (OMIM: 613368) PREDICTED: carnosine s ( 577) 3660 731.7 2.5e-210
>>NP_001159694 (OMIM: 613368) carnosine synthase 1 isofo (950 aa)
initn: 6487 init1: 6487 opt: 6487 Z-score: 6905.7 bits: 1289.1 E(85289): 0
Smith-Waterman score: 6487; 100.0% identity (100.0% similar) in 950 aa overlap (1-950:1-950)
10 20 30 40 50 60
pF1KE2 MLSLDPSGPEWDCPLGSKDLEEEGPWGGGSGLPPTGCFPGSWRQDVGLDCKGSPEGAEAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLSLDPSGPEWDCPLGSKDLEEEGPWGGGSGLPPTGCFPGSWRQDVGLDCKGSPEGAEAR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 AWTVYYYSLLQSCLQQAGLPETQDRGQVPRTGCPGAEVTLCVLGSPSTFLPVLLEGGVQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AWTVYYYSLLQSCLQQAGLPETQDRGQVPRTGCPGAEVTLCVLGSPSTFLPVLLEGGVQS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 PGNMLLCLSPAWLMKVPAPGQPGEAALLVSKAVSFHPGGLTFLDDFVPPRRATYFLAGLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGNMLLCLSPAWLMKVPAPGQPGEAALLVSKAVSFHPGGLTFLDDFVPPRRATYFLAGLG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 LGPGRGREAAELARDLTCPTGASAELARLLEDRLLTRQLLAQQGGVAVPATLAFTYKPPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGPGRGREAAELARDLTCPTGASAELARLLEDRLLTRQLLAQQGGVAVPATLAFTYKPPG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 LLRGGDASLGLRLVELSGKEGQETLVKEEVEAFLRSEALGDILQVAVKLSGWRWRGRQAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLRGGDASLGLRLVELSGKEGQETLVKEEVEAFLRSEALGDILQVAVKLSGWRWRGRQAW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 RLHPRAELGAVVDTVLALLEKLEEEESVLVEAVYPPAQLPCSDGPSPGPGLAVRICAVVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLHPRAELGAVVDTVLALLEKLEEEESVLVEAVYPPAQLPCSDGPSPGPGLAVRICAVVC
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 RTQGDRPLLSKVVCGVGRGDRPLRHHNSLPRTLEVALAQCGLGEEAQVAAVRQRVKAAAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RTQGDRPLLSKVVCGVGRGDRPLRHHNSLPRTLEVALAQCGLGEEAQVAAVRQRVKAAAE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 AALAAVLALEAGLSAEQRGGRRAHTDFLGVDFALTAAGGVLTPVALELNGGLCLEACGAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AALAAVLALEAGLSAEQRGGRRAHTDFLGVDFALTAAGGVLTPVALELNGGLCLEACGAL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 EGLWAAPRLGPAADEAVAAPLVETMLRRSARCLMEGKQLLVVGAGGVSKKFVWEAARDYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGLWAAPRLGPAADEAVAAPLVETMLRRSARCLMEGKQLLVVGAGGVSKKFVWEAARDYG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 LQLHLVESDPNHFASQLVQTFIHFDMTEHRRDEENARLLAELVRARGLKLDGCFSYWDDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQLHLVESDPNHFASQLVQTFIHFDMTEHRRDEENARLLAELVRARGLKLDGCFSYWDDC
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 LVLTALLCQELGLPCSSPAAMRLAKQKSLTQLHLLHHHGPPWPAPSLHAVPCCPLESEAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVLTALLCQELGLPCSSPAAMRLAKQKSLTQLHLLHHHGPPWPAPSLHAVPCCPLESEAD
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 VERAVHQVPLPGVMKLEFGAGAVGVRLVEDAPQCHEHFSRITRDLQGEADHPGIGLGWGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VERAVHQVPLPGVMKLEFGAGAVGVRLVEDAPQCHEHFSRITRDLQGEADHPGIGLGWGN
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 AMLLMEFVEGTEHDVDLVLFGGRLLAAFVSDNGPTRLPGFTETAACMPTGLAPEQEAQMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AMLLMEFVEGTEHDVDLVLFGGRLLAAFVSDNGPTRLPGFTETAACMPTGLAPEQEAQMV
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 QAAFRCCLGCGLLDGVFNVELKLTGAGPRLIEINPRMGGFYLRDWILELYGVDLLLAAVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QAAFRCCLGCGLLDGVFNVELKLTGAGPRLIEINPRMGGFYLRDWILELYGVDLLLAAVM
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 VACGLRPALPTRPRARGHLVGVMCLVSQHLQALSSTASRETLQALHDRGLLRLNLLEEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VACGLRPALPTRPRARGHLVGVMCLVSQHLQALSSTASRETLQALHDRGLLRLNLLEEAL
850 860 870 880 890 900
910 920 930 940 950
pF1KE2 VPGEYEEPYCSVACAGPSPTEARLRLLGLCQGLGIDGPSYPVAHFLSHFK
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPGEYEEPYCSVACAGPSPTEARLRLLGLCQGLGIDGPSYPVAHFLSHFK
910 920 930 940 950
>>XP_011543491 (OMIM: 613368) PREDICTED: carnosine synth (950 aa)
initn: 6487 init1: 6487 opt: 6487 Z-score: 6905.7 bits: 1289.1 E(85289): 0
Smith-Waterman score: 6487; 100.0% identity (100.0% similar) in 950 aa overlap (1-950:1-950)
10 20 30 40 50 60
pF1KE2 MLSLDPSGPEWDCPLGSKDLEEEGPWGGGSGLPPTGCFPGSWRQDVGLDCKGSPEGAEAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLSLDPSGPEWDCPLGSKDLEEEGPWGGGSGLPPTGCFPGSWRQDVGLDCKGSPEGAEAR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 AWTVYYYSLLQSCLQQAGLPETQDRGQVPRTGCPGAEVTLCVLGSPSTFLPVLLEGGVQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AWTVYYYSLLQSCLQQAGLPETQDRGQVPRTGCPGAEVTLCVLGSPSTFLPVLLEGGVQS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 PGNMLLCLSPAWLMKVPAPGQPGEAALLVSKAVSFHPGGLTFLDDFVPPRRATYFLAGLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGNMLLCLSPAWLMKVPAPGQPGEAALLVSKAVSFHPGGLTFLDDFVPPRRATYFLAGLG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 LGPGRGREAAELARDLTCPTGASAELARLLEDRLLTRQLLAQQGGVAVPATLAFTYKPPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGPGRGREAAELARDLTCPTGASAELARLLEDRLLTRQLLAQQGGVAVPATLAFTYKPPG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 LLRGGDASLGLRLVELSGKEGQETLVKEEVEAFLRSEALGDILQVAVKLSGWRWRGRQAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLRGGDASLGLRLVELSGKEGQETLVKEEVEAFLRSEALGDILQVAVKLSGWRWRGRQAW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 RLHPRAELGAVVDTVLALLEKLEEEESVLVEAVYPPAQLPCSDGPSPGPGLAVRICAVVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLHPRAELGAVVDTVLALLEKLEEEESVLVEAVYPPAQLPCSDGPSPGPGLAVRICAVVC
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 RTQGDRPLLSKVVCGVGRGDRPLRHHNSLPRTLEVALAQCGLGEEAQVAAVRQRVKAAAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTQGDRPLLSKVVCGVGRGDRPLRHHNSLPRTLEVALAQCGLGEEAQVAAVRQRVKAAAE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 AALAAVLALEAGLSAEQRGGRRAHTDFLGVDFALTAAGGVLTPVALELNGGLCLEACGAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AALAAVLALEAGLSAEQRGGRRAHTDFLGVDFALTAAGGVLTPVALELNGGLCLEACGAL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 EGLWAAPRLGPAADEAVAAPLVETMLRRSARCLMEGKQLLVVGAGGVSKKFVWEAARDYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGLWAAPRLGPAADEAVAAPLVETMLRRSARCLMEGKQLLVVGAGGVSKKFVWEAARDYG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 LQLHLVESDPNHFASQLVQTFIHFDMTEHRRDEENARLLAELVRARGLKLDGCFSYWDDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQLHLVESDPNHFASQLVQTFIHFDMTEHRRDEENARLLAELVRARGLKLDGCFSYWDDC
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 LVLTALLCQELGLPCSSPAAMRLAKQKSLTQLHLLHHHGPPWPAPSLHAVPCCPLESEAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVLTALLCQELGLPCSSPAAMRLAKQKSLTQLHLLHHHGPPWPAPSLHAVPCCPLESEAD
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 VERAVHQVPLPGVMKLEFGAGAVGVRLVEDAPQCHEHFSRITRDLQGEADHPGIGLGWGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VERAVHQVPLPGVMKLEFGAGAVGVRLVEDAPQCHEHFSRITRDLQGEADHPGIGLGWGN
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 AMLLMEFVEGTEHDVDLVLFGGRLLAAFVSDNGPTRLPGFTETAACMPTGLAPEQEAQMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AMLLMEFVEGTEHDVDLVLFGGRLLAAFVSDNGPTRLPGFTETAACMPTGLAPEQEAQMV
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 QAAFRCCLGCGLLDGVFNVELKLTGAGPRLIEINPRMGGFYLRDWILELYGVDLLLAAVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QAAFRCCLGCGLLDGVFNVELKLTGAGPRLIEINPRMGGFYLRDWILELYGVDLLLAAVM
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 VACGLRPALPTRPRARGHLVGVMCLVSQHLQALSSTASRETLQALHDRGLLRLNLLEEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VACGLRPALPTRPRARGHLVGVMCLVSQHLQALSSTASRETLQALHDRGLLRLNLLEEAL
850 860 870 880 890 900
910 920 930 940 950
pF1KE2 VPGEYEEPYCSVACAGPSPTEARLRLLGLCQGLGIDGPSYPVAHFLSHFK
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPGEYEEPYCSVACAGPSPTEARLRLLGLCQGLGIDGPSYPVAHFLSHFK
910 920 930 940 950
>>XP_016873543 (OMIM: 613368) PREDICTED: carnosine synth (966 aa)
initn: 6480 init1: 6480 opt: 6480 Z-score: 6898.1 bits: 1287.8 E(85289): 0
Smith-Waterman score: 6480; 100.0% identity (100.0% similar) in 949 aa overlap (2-950:18-966)
10 20 30 40
pF1KE2 MLSLDPSGPEWDCPLGSKDLEEEGPWGGGSGLPPTGCFPGSWRQ
:::::::::::::::::::::::::::::::::::::::::::
XP_016 MCPLAHPAQDLPLLPSQLSLDPSGPEWDCPLGSKDLEEEGPWGGGSGLPPTGCFPGSWRQ
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE2 DVGLDCKGSPEGAEARAWTVYYYSLLQSCLQQAGLPETQDRGQVPRTGCPGAEVTLCVLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVGLDCKGSPEGAEARAWTVYYYSLLQSCLQQAGLPETQDRGQVPRTGCPGAEVTLCVLG
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE2 SPSTFLPVLLEGGVQSPGNMLLCLSPAWLMKVPAPGQPGEAALLVSKAVSFHPGGLTFLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPSTFLPVLLEGGVQSPGNMLLCLSPAWLMKVPAPGQPGEAALLVSKAVSFHPGGLTFLD
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE2 DFVPPRRATYFLAGLGLGPGRGREAAELARDLTCPTGASAELARLLEDRLLTRQLLAQQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DFVPPRRATYFLAGLGLGPGRGREAAELARDLTCPTGASAELARLLEDRLLTRQLLAQQG
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE2 GVAVPATLAFTYKPPGLLRGGDASLGLRLVELSGKEGQETLVKEEVEAFLRSEALGDILQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GVAVPATLAFTYKPPGLLRGGDASLGLRLVELSGKEGQETLVKEEVEAFLRSEALGDILQ
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE2 VAVKLSGWRWRGRQAWRLHPRAELGAVVDTVLALLEKLEEEESVLVEAVYPPAQLPCSDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAVKLSGWRWRGRQAWRLHPRAELGAVVDTVLALLEKLEEEESVLVEAVYPPAQLPCSDG
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE2 PSPGPGLAVRICAVVCRTQGDRPLLSKVVCGVGRGDRPLRHHNSLPRTLEVALAQCGLGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSPGPGLAVRICAVVCRTQGDRPLLSKVVCGVGRGDRPLRHHNSLPRTLEVALAQCGLGE
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE2 EAQVAAVRQRVKAAAEAALAAVLALEAGLSAEQRGGRRAHTDFLGVDFALTAAGGVLTPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAQVAAVRQRVKAAAEAALAAVLALEAGLSAEQRGGRRAHTDFLGVDFALTAAGGVLTPV
430 440 450 460 470 480
470 480 490 500 510 520
pF1KE2 ALELNGGLCLEACGALEGLWAAPRLGPAADEAVAAPLVETMLRRSARCLMEGKQLLVVGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALELNGGLCLEACGALEGLWAAPRLGPAADEAVAAPLVETMLRRSARCLMEGKQLLVVGA
490 500 510 520 530 540
530 540 550 560 570 580
pF1KE2 GGVSKKFVWEAARDYGLQLHLVESDPNHFASQLVQTFIHFDMTEHRRDEENARLLAELVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGVSKKFVWEAARDYGLQLHLVESDPNHFASQLVQTFIHFDMTEHRRDEENARLLAELVR
550 560 570 580 590 600
590 600 610 620 630 640
pF1KE2 ARGLKLDGCFSYWDDCLVLTALLCQELGLPCSSPAAMRLAKQKSLTQLHLLHHHGPPWPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARGLKLDGCFSYWDDCLVLTALLCQELGLPCSSPAAMRLAKQKSLTQLHLLHHHGPPWPA
610 620 630 640 650 660
650 660 670 680 690 700
pF1KE2 PSLHAVPCCPLESEADVERAVHQVPLPGVMKLEFGAGAVGVRLVEDAPQCHEHFSRITRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSLHAVPCCPLESEADVERAVHQVPLPGVMKLEFGAGAVGVRLVEDAPQCHEHFSRITRD
670 680 690 700 710 720
710 720 730 740 750 760
pF1KE2 LQGEADHPGIGLGWGNAMLLMEFVEGTEHDVDLVLFGGRLLAAFVSDNGPTRLPGFTETA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQGEADHPGIGLGWGNAMLLMEFVEGTEHDVDLVLFGGRLLAAFVSDNGPTRLPGFTETA
730 740 750 760 770 780
770 780 790 800 810 820
pF1KE2 ACMPTGLAPEQEAQMVQAAFRCCLGCGLLDGVFNVELKLTGAGPRLIEINPRMGGFYLRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ACMPTGLAPEQEAQMVQAAFRCCLGCGLLDGVFNVELKLTGAGPRLIEINPRMGGFYLRD
790 800 810 820 830 840
830 840 850 860 870 880
pF1KE2 WILELYGVDLLLAAVMVACGLRPALPTRPRARGHLVGVMCLVSQHLQALSSTASRETLQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WILELYGVDLLLAAVMVACGLRPALPTRPRARGHLVGVMCLVSQHLQALSSTASRETLQA
850 860 870 880 890 900
890 900 910 920 930 940
pF1KE2 LHDRGLLRLNLLEEALVPGEYEEPYCSVACAGPSPTEARLRLLGLCQGLGIDGPSYPVAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHDRGLLRLNLLEEALVPGEYEEPYCSVACAGPSPTEARLRLLGLCQGLGIDGPSYPVAH
910 920 930 940 950 960
950
pF1KE2 FLSHFK
::::::
XP_016 FLSHFK
>>XP_016873544 (OMIM: 613368) PREDICTED: carnosine synth (936 aa)
initn: 5607 init1: 5607 opt: 5607 Z-score: 5968.3 bits: 1115.7 E(85289): 0
Smith-Waterman score: 6202; 96.8% identity (96.8% similar) in 949 aa overlap (2-950:18-936)
10 20 30 40
pF1KE2 MLSLDPSGPEWDCPLGSKDLEEEGPWGGGSGLPPTGCFPGSWRQ
:::::::::::::::::::::::::::::::::::::::::::
XP_016 MCPLAHPAQDLPLLPSQLSLDPSGPEWDCPLGSKDLEEEGPWGGGSGLPPTGCFPGSWRQ
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE2 DVGLDCKGSPEGAEARAWTVYYYSLLQSCLQQAGLPETQDRGQVPRTGCPGAEVTLCVLG
::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVGLDCKGSPEGAEARAWTVYYYSLLQSCLQQAGLPETQDRGQVPRTG------------
70 80 90 100
110 120 130 140 150 160
pF1KE2 SPSTFLPVLLEGGVQSPGNMLLCLSPAWLMKVPAPGQPGEAALLVSKAVSFHPGGLTFLD
::::::::::::::::::::::::::::::::::::::::::
XP_016 ------------------NMLLCLSPAWLMKVPAPGQPGEAALLVSKAVSFHPGGLTFLD
110 120 130 140 150
170 180 190 200 210 220
pF1KE2 DFVPPRRATYFLAGLGLGPGRGREAAELARDLTCPTGASAELARLLEDRLLTRQLLAQQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DFVPPRRATYFLAGLGLGPGRGREAAELARDLTCPTGASAELARLLEDRLLTRQLLAQQG
160 170 180 190 200 210
230 240 250 260 270 280
pF1KE2 GVAVPATLAFTYKPPGLLRGGDASLGLRLVELSGKEGQETLVKEEVEAFLRSEALGDILQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GVAVPATLAFTYKPPGLLRGGDASLGLRLVELSGKEGQETLVKEEVEAFLRSEALGDILQ
220 230 240 250 260 270
290 300 310 320 330 340
pF1KE2 VAVKLSGWRWRGRQAWRLHPRAELGAVVDTVLALLEKLEEEESVLVEAVYPPAQLPCSDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAVKLSGWRWRGRQAWRLHPRAELGAVVDTVLALLEKLEEEESVLVEAVYPPAQLPCSDG
280 290 300 310 320 330
350 360 370 380 390 400
pF1KE2 PSPGPGLAVRICAVVCRTQGDRPLLSKVVCGVGRGDRPLRHHNSLPRTLEVALAQCGLGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSPGPGLAVRICAVVCRTQGDRPLLSKVVCGVGRGDRPLRHHNSLPRTLEVALAQCGLGE
340 350 360 370 380 390
410 420 430 440 450 460
pF1KE2 EAQVAAVRQRVKAAAEAALAAVLALEAGLSAEQRGGRRAHTDFLGVDFALTAAGGVLTPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAQVAAVRQRVKAAAEAALAAVLALEAGLSAEQRGGRRAHTDFLGVDFALTAAGGVLTPV
400 410 420 430 440 450
470 480 490 500 510 520
pF1KE2 ALELNGGLCLEACGALEGLWAAPRLGPAADEAVAAPLVETMLRRSARCLMEGKQLLVVGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALELNGGLCLEACGALEGLWAAPRLGPAADEAVAAPLVETMLRRSARCLMEGKQLLVVGA
460 470 480 490 500 510
530 540 550 560 570 580
pF1KE2 GGVSKKFVWEAARDYGLQLHLVESDPNHFASQLVQTFIHFDMTEHRRDEENARLLAELVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGVSKKFVWEAARDYGLQLHLVESDPNHFASQLVQTFIHFDMTEHRRDEENARLLAELVR
520 530 540 550 560 570
590 600 610 620 630 640
pF1KE2 ARGLKLDGCFSYWDDCLVLTALLCQELGLPCSSPAAMRLAKQKSLTQLHLLHHHGPPWPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARGLKLDGCFSYWDDCLVLTALLCQELGLPCSSPAAMRLAKQKSLTQLHLLHHHGPPWPA
580 590 600 610 620 630
650 660 670 680 690 700
pF1KE2 PSLHAVPCCPLESEADVERAVHQVPLPGVMKLEFGAGAVGVRLVEDAPQCHEHFSRITRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSLHAVPCCPLESEADVERAVHQVPLPGVMKLEFGAGAVGVRLVEDAPQCHEHFSRITRD
640 650 660 670 680 690
710 720 730 740 750 760
pF1KE2 LQGEADHPGIGLGWGNAMLLMEFVEGTEHDVDLVLFGGRLLAAFVSDNGPTRLPGFTETA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQGEADHPGIGLGWGNAMLLMEFVEGTEHDVDLVLFGGRLLAAFVSDNGPTRLPGFTETA
700 710 720 730 740 750
770 780 790 800 810 820
pF1KE2 ACMPTGLAPEQEAQMVQAAFRCCLGCGLLDGVFNVELKLTGAGPRLIEINPRMGGFYLRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ACMPTGLAPEQEAQMVQAAFRCCLGCGLLDGVFNVELKLTGAGPRLIEINPRMGGFYLRD
760 770 780 790 800 810
830 840 850 860 870 880
pF1KE2 WILELYGVDLLLAAVMVACGLRPALPTRPRARGHLVGVMCLVSQHLQALSSTASRETLQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WILELYGVDLLLAAVMVACGLRPALPTRPRARGHLVGVMCLVSQHLQALSSTASRETLQA
820 830 840 850 860 870
890 900 910 920 930 940
pF1KE2 LHDRGLLRLNLLEEALVPGEYEEPYCSVACAGPSPTEARLRLLGLCQGLGIDGPSYPVAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHDRGLLRLNLLEEALVPGEYEEPYCSVACAGPSPTEARLRLLGLCQGLGIDGPSYPVAH
880 890 900 910 920 930
950
pF1KE2 FLSHFK
::::::
XP_016 FLSHFK
>>NP_065862 (OMIM: 613368) carnosine synthase 1 isoform (827 aa)
initn: 5584 init1: 5584 opt: 5584 Z-score: 5944.5 bits: 1111.1 E(85289): 0
Smith-Waterman score: 5584; 100.0% identity (100.0% similar) in 827 aa overlap (124-950:1-827)
100 110 120 130 140 150
pF1KE2 PGAEVTLCVLGSPSTFLPVLLEGGVQSPGNMLLCLSPAWLMKVPAPGQPGEAALLVSKAV
::::::::::::::::::::::::::::::
NP_065 MLLCLSPAWLMKVPAPGQPGEAALLVSKAV
10 20 30
160 170 180 190 200 210
pF1KE2 SFHPGGLTFLDDFVPPRRATYFLAGLGLGPGRGREAAELARDLTCPTGASAELARLLEDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 SFHPGGLTFLDDFVPPRRATYFLAGLGLGPGRGREAAELARDLTCPTGASAELARLLEDR
40 50 60 70 80 90
220 230 240 250 260 270
pF1KE2 LLTRQLLAQQGGVAVPATLAFTYKPPGLLRGGDASLGLRLVELSGKEGQETLVKEEVEAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LLTRQLLAQQGGVAVPATLAFTYKPPGLLRGGDASLGLRLVELSGKEGQETLVKEEVEAF
100 110 120 130 140 150
280 290 300 310 320 330
pF1KE2 LRSEALGDILQVAVKLSGWRWRGRQAWRLHPRAELGAVVDTVLALLEKLEEEESVLVEAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LRSEALGDILQVAVKLSGWRWRGRQAWRLHPRAELGAVVDTVLALLEKLEEEESVLVEAV
160 170 180 190 200 210
340 350 360 370 380 390
pF1KE2 YPPAQLPCSDGPSPGPGLAVRICAVVCRTQGDRPLLSKVVCGVGRGDRPLRHHNSLPRTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 YPPAQLPCSDGPSPGPGLAVRICAVVCRTQGDRPLLSKVVCGVGRGDRPLRHHNSLPRTL
220 230 240 250 260 270
400 410 420 430 440 450
pF1KE2 EVALAQCGLGEEAQVAAVRQRVKAAAEAALAAVLALEAGLSAEQRGGRRAHTDFLGVDFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 EVALAQCGLGEEAQVAAVRQRVKAAAEAALAAVLALEAGLSAEQRGGRRAHTDFLGVDFA
280 290 300 310 320 330
460 470 480 490 500 510
pF1KE2 LTAAGGVLTPVALELNGGLCLEACGALEGLWAAPRLGPAADEAVAAPLVETMLRRSARCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LTAAGGVLTPVALELNGGLCLEACGALEGLWAAPRLGPAADEAVAAPLVETMLRRSARCL
340 350 360 370 380 390
520 530 540 550 560 570
pF1KE2 MEGKQLLVVGAGGVSKKFVWEAARDYGLQLHLVESDPNHFASQLVQTFIHFDMTEHRRDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MEGKQLLVVGAGGVSKKFVWEAARDYGLQLHLVESDPNHFASQLVQTFIHFDMTEHRRDE
400 410 420 430 440 450
580 590 600 610 620 630
pF1KE2 ENARLLAELVRARGLKLDGCFSYWDDCLVLTALLCQELGLPCSSPAAMRLAKQKSLTQLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 ENARLLAELVRARGLKLDGCFSYWDDCLVLTALLCQELGLPCSSPAAMRLAKQKSLTQLH
460 470 480 490 500 510
640 650 660 670 680 690
pF1KE2 LLHHHGPPWPAPSLHAVPCCPLESEADVERAVHQVPLPGVMKLEFGAGAVGVRLVEDAPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LLHHHGPPWPAPSLHAVPCCPLESEADVERAVHQVPLPGVMKLEFGAGAVGVRLVEDAPQ
520 530 540 550 560 570
700 710 720 730 740 750
pF1KE2 CHEHFSRITRDLQGEADHPGIGLGWGNAMLLMEFVEGTEHDVDLVLFGGRLLAAFVSDNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 CHEHFSRITRDLQGEADHPGIGLGWGNAMLLMEFVEGTEHDVDLVLFGGRLLAAFVSDNG
580 590 600 610 620 630
760 770 780 790 800 810
pF1KE2 PTRLPGFTETAACMPTGLAPEQEAQMVQAAFRCCLGCGLLDGVFNVELKLTGAGPRLIEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 PTRLPGFTETAACMPTGLAPEQEAQMVQAAFRCCLGCGLLDGVFNVELKLTGAGPRLIEI
640 650 660 670 680 690
820 830 840 850 860 870
pF1KE2 NPRMGGFYLRDWILELYGVDLLLAAVMVACGLRPALPTRPRARGHLVGVMCLVSQHLQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 NPRMGGFYLRDWILELYGVDLLLAAVMVACGLRPALPTRPRARGHLVGVMCLVSQHLQAL
700 710 720 730 740 750
880 890 900 910 920 930
pF1KE2 SSTASRETLQALHDRGLLRLNLLEEALVPGEYEEPYCSVACAGPSPTEARLRLLGLCQGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 SSTASRETLQALHDRGLLRLNLLEEALVPGEYEEPYCSVACAGPSPTEARLRLLGLCQGL
760 770 780 790 800 810
940 950
pF1KE2 GIDGPSYPVAHFLSHFK
:::::::::::::::::
NP_065 GIDGPSYPVAHFLSHFK
820
>>XP_011543493 (OMIM: 613368) PREDICTED: carnosine synth (577 aa)
initn: 3660 init1: 3660 opt: 3660 Z-score: 3897.1 bits: 731.7 E(85289): 2.5e-210
Smith-Waterman score: 3660; 100.0% identity (100.0% similar) in 541 aa overlap (2-542:18-558)
10 20 30 40
pF1KE2 MLSLDPSGPEWDCPLGSKDLEEEGPWGGGSGLPPTGCFPGSWRQ
:::::::::::::::::::::::::::::::::::::::::::
XP_011 MCPLAHPAQDLPLLPSQLSLDPSGPEWDCPLGSKDLEEEGPWGGGSGLPPTGCFPGSWRQ
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE2 DVGLDCKGSPEGAEARAWTVYYYSLLQSCLQQAGLPETQDRGQVPRTGCPGAEVTLCVLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVGLDCKGSPEGAEARAWTVYYYSLLQSCLQQAGLPETQDRGQVPRTGCPGAEVTLCVLG
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE2 SPSTFLPVLLEGGVQSPGNMLLCLSPAWLMKVPAPGQPGEAALLVSKAVSFHPGGLTFLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPSTFLPVLLEGGVQSPGNMLLCLSPAWLMKVPAPGQPGEAALLVSKAVSFHPGGLTFLD
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE2 DFVPPRRATYFLAGLGLGPGRGREAAELARDLTCPTGASAELARLLEDRLLTRQLLAQQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DFVPPRRATYFLAGLGLGPGRGREAAELARDLTCPTGASAELARLLEDRLLTRQLLAQQG
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE2 GVAVPATLAFTYKPPGLLRGGDASLGLRLVELSGKEGQETLVKEEVEAFLRSEALGDILQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GVAVPATLAFTYKPPGLLRGGDASLGLRLVELSGKEGQETLVKEEVEAFLRSEALGDILQ
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE2 VAVKLSGWRWRGRQAWRLHPRAELGAVVDTVLALLEKLEEEESVLVEAVYPPAQLPCSDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAVKLSGWRWRGRQAWRLHPRAELGAVVDTVLALLEKLEEEESVLVEAVYPPAQLPCSDG
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE2 PSPGPGLAVRICAVVCRTQGDRPLLSKVVCGVGRGDRPLRHHNSLPRTLEVALAQCGLGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSPGPGLAVRICAVVCRTQGDRPLLSKVVCGVGRGDRPLRHHNSLPRTLEVALAQCGLGE
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE2 EAQVAAVRQRVKAAAEAALAAVLALEAGLSAEQRGGRRAHTDFLGVDFALTAAGGVLTPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAQVAAVRQRVKAAAEAALAAVLALEAGLSAEQRGGRRAHTDFLGVDFALTAAGGVLTPV
430 440 450 460 470 480
470 480 490 500 510 520
pF1KE2 ALELNGGLCLEACGALEGLWAAPRLGPAADEAVAAPLVETMLRRSARCLMEGKQLLVVGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALELNGGLCLEACGALEGLWAAPRLGPAADEAVAAPLVETMLRRSARCLMEGKQLLVVGA
490 500 510 520 530 540
530 540 550 560 570 580
pF1KE2 GGVSKKFVWEAARDYGLQLHLVESDPNHFASQLVQTFIHFDMTEHRRDEENARLLAELVR
::::::::::::::::::
XP_011 GGVSKKFVWEAARDYGLQAGVEWRNLGPLQPLPPGFK
550 560 570
950 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 22:46:36 2016 done: Sat Nov 5 22:46:38 2016
Total Scan time: 16.240 Total Display time: 0.190
Function used was FASTA [36.3.4 Apr, 2011]