Result of FASTA (ccds) for
pFN21AE2592
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2592, 224 aa
1>>>pF1KE2592 224 - 224 aa - 224 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.5285+/-0.000683; mu= 18.0393+/- 0.041
mean_var=59.8033+/-11.842, 0's: 0 Z-trim(109.6): 28 B-trim: 0 in 0/50
Lambda= 0.165849
statistics sampled from 10953 (10976) to 10953 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.723), E-opt: 0.2 (0.337), width: 16
Scan time: 1.410
The best scores are: opt bits E(32554)
CCDS4120.1 TMED7 gene_id:51014|Hs108|chr5 ( 224) 1507 368.4 2e-102
CCDS54887.1 TICAM2 gene_id:100302736|Hs108|chr5 ( 404) 1302 319.6 1.9e-87
CCDS54888.1 TICAM2 gene_id:100302736|Hs108|chr5 ( 188) 1287 315.7 1.3e-86
CCDS10310.1 TMED3 gene_id:23423|Hs108|chr15 ( 217) 956 236.6 9.7e-63
CCDS73768.1 TMED3 gene_id:23423|Hs108|chr15 ( 155) 600 151.3 3.3e-37
CCDS81914.1 TMED3 gene_id:23423|Hs108|chr15 ( 173) 594 149.9 9.7e-37
CCDS9250.1 TMED2 gene_id:10959|Hs108|chr12 ( 201) 407 105.2 3.2e-23
CCDS53342.1 TMED5 gene_id:50999|Hs108|chr1 ( 193) 261 70.2 1e-12
CCDS9840.1 TMED10 gene_id:10972|Hs108|chr14 ( 219) 258 69.6 1.8e-12
CCDS12249.1 TMED1 gene_id:11018|Hs108|chr19 ( 227) 256 69.1 2.6e-12
CCDS5493.1 TMED4 gene_id:222068|Hs108|chr7 ( 227) 242 65.7 2.7e-11
CCDS4428.1 TMED9 gene_id:54732|Hs108|chr5 ( 235) 238 64.8 5.3e-11
>>CCDS4120.1 TMED7 gene_id:51014|Hs108|chr5 (224 aa)
initn: 1507 init1: 1507 opt: 1507 Z-score: 1952.2 bits: 368.4 E(32554): 2e-102
Smith-Waterman score: 1507; 100.0% identity (100.0% similar) in 224 aa overlap (1-224:1-224)
10 20 30 40 50 60
pF1KE2 MPRPGSAQRWAAVAGRWGCRLLALLLLVPGPGGASEITFELPDNAKQCFYEDIAQGTKCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 MPRPGSAQRWAAVAGRWGCRLLALLLLVPGPGGASEITFELPDNAKQCFYEDIAQGTKCT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LEFQVITGGHYDVDCRLEDPDGKVLYKEMKKQYDSFTFTASKNGTYKFCFSNEFSTFTHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 LEFQVITGGHYDVDCRLEDPDGKVLYKEMKKQYDSFTFTASKNGTYKFCFSNEFSTFTHK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 TVYFDFQVGEDPPLFPSENRVSALTQMESACVSIHEALKSVIDYQTHFRLREAQGRSRAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 TVYFDFQVGEDPPLFPSENRVSALTQMESACVSIHEALKSVIDYQTHFRLREAQGRSRAE
130 140 150 160 170 180
190 200 210 220
pF1KE2 DLNTRVAYWSVGEALILLVVSIGQVFLLKSFFSDKRTTTTRVGS
::::::::::::::::::::::::::::::::::::::::::::
CCDS41 DLNTRVAYWSVGEALILLVVSIGQVFLLKSFFSDKRTTTTRVGS
190 200 210 220
>>CCDS54887.1 TICAM2 gene_id:100302736|Hs108|chr5 (404 aa)
initn: 1302 init1: 1302 opt: 1302 Z-score: 1683.6 bits: 319.6 E(32554): 1.9e-87
Smith-Waterman score: 1302; 100.0% identity (100.0% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE2 MPRPGSAQRWAAVAGRWGCRLLALLLLVPGPGGASEITFELPDNAKQCFYEDIAQGTKCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 MPRPGSAQRWAAVAGRWGCRLLALLLLVPGPGGASEITFELPDNAKQCFYEDIAQGTKCT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LEFQVITGGHYDVDCRLEDPDGKVLYKEMKKQYDSFTFTASKNGTYKFCFSNEFSTFTHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 LEFQVITGGHYDVDCRLEDPDGKVLYKEMKKQYDSFTFTASKNGTYKFCFSNEFSTFTHK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 TVYFDFQVGEDPPLFPSENRVSALTQMESACVSIHEALKSVIDYQTHFRLREAQGRSRAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 TVYFDFQVGEDPPLFPSENRVSALTQMESACVSIHEALKSVIDYQTHFRLREAQGRSRAE
130 140 150 160 170 180
190 200 210 220
pF1KE2 DLNTRVAYWSVGEALILLVVSIGQVFLLKSFFSDKRTTTTRVGS
:::::::::
CCDS54 DLNTRVAYWHSVDTSPGYHESDSKKSEDLSLCNVAEHSNTTEGPTGKQEGAQSVEEMFEE
190 200 210 220 230 240
>>CCDS54888.1 TICAM2 gene_id:100302736|Hs108|chr5 (188 aa)
initn: 1287 init1: 1287 opt: 1287 Z-score: 1668.7 bits: 315.7 E(32554): 1.3e-86
Smith-Waterman score: 1287; 100.0% identity (100.0% similar) in 188 aa overlap (1-188:1-188)
10 20 30 40 50 60
pF1KE2 MPRPGSAQRWAAVAGRWGCRLLALLLLVPGPGGASEITFELPDNAKQCFYEDIAQGTKCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 MPRPGSAQRWAAVAGRWGCRLLALLLLVPGPGGASEITFELPDNAKQCFYEDIAQGTKCT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LEFQVITGGHYDVDCRLEDPDGKVLYKEMKKQYDSFTFTASKNGTYKFCFSNEFSTFTHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 LEFQVITGGHYDVDCRLEDPDGKVLYKEMKKQYDSFTFTASKNGTYKFCFSNEFSTFTHK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 TVYFDFQVGEDPPLFPSENRVSALTQMESACVSIHEALKSVIDYQTHFRLREAQGRSRAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 TVYFDFQVGEDPPLFPSENRVSALTQMESACVSIHEALKSVIDYQTHFRLREAQGRSRAE
130 140 150 160 170 180
190 200 210 220
pF1KE2 DLNTRVAYWSVGEALILLVVSIGQVFLLKSFFSDKRTTTTRVGS
::::::::
CCDS54 DLNTRVAY
>>CCDS10310.1 TMED3 gene_id:23423|Hs108|chr15 (217 aa)
initn: 945 init1: 554 opt: 956 Z-score: 1239.9 bits: 236.6 E(32554): 9.7e-63
Smith-Waterman score: 956; 68.6% identity (88.4% similar) in 207 aa overlap (21-224:12-217)
10 20 30 40 50
pF1KE2 MPRPGSAQRWAAVAGRWGCRLLALLLL--VPGPGGASEITFELPDNAKQCFYEDIAQGTK
:: :::: . : :: :.::::::::::::.:.. ::.:
CCDS10 MGSTVPRSASVLLLLLLLRRAEQPCGA-ELTFELPDNAKQCFHEEVEQGVK
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 CTLEFQVITGGHYDVDCRLEDPDGKVLYKEMKKQYDSFTFTASKNGTYKFCFSNEFSTFT
.:..:::::::::::: .:::.:...:.: ::::::::. : .:.:.::::::::::.
CCDS10 FSLDYQVITGGHYDVDCYVEDPQGNTIYRETKKQYDSFTYRAEVKGVYQFCFSNEFSTFS
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE2 HKTVYFDFQVGEDPPLFPSE-NRVSALTQMESACVSIHEALKSVIDYQTHFRLREAQGRS
:::::::::::..::..:. :::.::::::::::.::::::.::: :::.:::::: :.
CCDS10 HKTVYFDFQVGDEPPILPDMGNRVTALTQMESACVTIHEALKTVIDSQTHYRLREAQDRA
120 130 140 150 160 170
180 190 200 210 220
pF1KE2 RAEDLNTRVAYWSVGEALILLVVSIGQVFLLKSFFSDKRTTTTRVGS
::::::.::.::::::.. :.:::..::.::::::..:: . : :
CCDS10 RAEDLNSRVSYWSVGETIALFVVSFSQVLLLKSFFTEKRPISRAVHS
180 190 200 210
>>CCDS73768.1 TMED3 gene_id:23423|Hs108|chr15 (155 aa)
initn: 604 init1: 554 opt: 600 Z-score: 781.5 bits: 151.3 E(32554): 3.3e-37
Smith-Waterman score: 600; 66.9% identity (86.5% similar) in 133 aa overlap (21-150:12-143)
10 20 30 40 50
pF1KE2 MPRPGSAQRWAAVAGRWGCRLLALLLL--VPGPGGASEITFELPDNAKQCFYEDIAQGTK
:: :::: . : :: :.::::::::::::.:.. ::.:
CCDS73 MGSTVPRSASVLLLLLLLRRAEQPCGA-ELTFELPDNAKQCFHEEVEQGVK
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 CTLEFQVITGGHYDVDCRLEDPDGKVLYKEMKKQYDSFTFTASKNGTYKFCFSNEFSTFT
.:..:::::::::::: .:::.:...:.: ::::::::. : .:.:.::::::::::.
CCDS73 FSLDYQVITGGHYDVDCYVEDPQGNTIYRETKKQYDSFTYRAEVKGVYQFCFSNEFSTFS
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE2 HKTVYFDFQVGEDPPLFPSE-NRVSALTQMESACVSIHEALKSVIDYQTHFRLREAQGRS
:::::::::::..::..:. :::.:::: ::
CCDS73 HKTVYFDFQVGDEPPILPDMGNRVTALTQGPSASPTPTPPLRVPV
120 130 140 150
180 190 200 210 220
pF1KE2 RAEDLNTRVAYWSVGEALILLVVSIGQVFLLKSFFSDKRTTTTRVGS
>>CCDS81914.1 TMED3 gene_id:23423|Hs108|chr15 (173 aa)
initn: 615 init1: 554 opt: 594 Z-score: 773.1 bits: 149.9 E(32554): 9.7e-37
Smith-Waterman score: 594; 67.4% identity (87.6% similar) in 129 aa overlap (21-146:12-139)
10 20 30 40 50
pF1KE2 MPRPGSAQRWAAVAGRWGCRLLALLLL--VPGPGGASEITFELPDNAKQCFYEDIAQGTK
:: :::: . : :: :.::::::::::::.:.. ::.:
CCDS81 MGSTVPRSASVLLLLLLLRRAEQPCGA-ELTFELPDNAKQCFHEEVEQGVK
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 CTLEFQVITGGHYDVDCRLEDPDGKVLYKEMKKQYDSFTFTASKNGTYKFCFSNEFSTFT
.:..:::::::::::: .:::.:...:.: ::::::::. : .:.:.::::::::::.
CCDS81 FSLDYQVITGGHYDVDCYVEDPQGNTIYRETKKQYDSFTYRAEVKGVYQFCFSNEFSTFS
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE2 HKTVYFDFQVGEDPPLFPSE-NRVSALTQMESACVSIHEALKSVIDYQTHFRLREAQGRS
:::::::::::..::..:. :::.::::
CCDS81 HKTVYFDFQVGDEPPILPDMGNRVTALTQRFRGAYWKEVDKMVDYMQPGGTPATEGLGRL
120 130 140 150 160 170
>>CCDS9250.1 TMED2 gene_id:10959|Hs108|chr12 (201 aa)
initn: 400 init1: 279 opt: 407 Z-score: 530.4 bits: 105.2 E(32554): 3.2e-23
Smith-Waterman score: 407; 35.2% identity (65.8% similar) in 193 aa overlap (24-216:8-199)
10 20 30 40 50 60
pF1KE2 MPRPGSAQRWAAVAGRWGCRLLALLLLVPGPGGASEITFELPDNAKQCFYEDIAQGTKCT
:.::. . .: . .:..::.: ...:::
CCDS92 MVTLAELLVLLAALLATVSGYFVSIDAHAEECFFERVTSGTKMG
10 20 30 40
70 80 90 100 110 120
pF1KE2 LEFQVITGGHYDVDCRLEDPDGKVLYKEMKKQYDSFTFTASKNGTYKFCFSNEFSTFTHK
: :.: :: :.: .. ::.: .:: ... ..::.: .:::::::::..::.: :
CCDS92 LIFEVAEGGFLDIDVEITGPDNKGIYKGDRESSGKYTFAAHMDGTYKFCFSNRMSTMTPK
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE2 TVYFDFQVGEDPPLFPSENRVSALTQMESACVSIHEALKSVIDYQTHFRLREAQGRSRAE
:.: ...:: : :... ...: . :. .: : ....:: :. .
CCDS92 IVMFTIDIGEAPKGQDMETEAHQ-NKLEEMINELAVAMTAVKHEQEYMEVRERIHRAIND
110 120 130 140 150 160
190 200 210 220
pF1KE2 DLNTRVAYWSVGEALILLVVSIGQVFLLKSFFSDKRTTTTRVGS
. :.::. :: :::.:.....::.. :: :: .:
CCDS92 NTNSRVVLWSFFEALVLVAMTLGQIYYLKRFFEVRRVV
170 180 190 200
>>CCDS53342.1 TMED5 gene_id:50999|Hs108|chr1 (193 aa)
initn: 221 init1: 139 opt: 261 Z-score: 341.8 bits: 70.2 E(32554): 1e-12
Smith-Waterman score: 261; 28.9% identity (62.2% similar) in 180 aa overlap (21-190:13-188)
10 20 30 40 50
pF1KE2 MPRPGSAQRWAAVAGRWGCRLLALL--LLVPGPGG-----ASEITFELPDNAKQCFYEDI
::: : .:.:: .: :..:: :: . :.:::. .
CCDS53 MGDKIWLPFPVLLLAALPPVLLPGAAGFTPSLDSDFTFTLPAGQKECFYQPM
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 AQGTKCTLEFQVITGGHYDVDCRLEDPDGKVLYKEMKKQYDSFTFTASKNGTYKFCFSNE
.. .:.::. :. :.: .: .:.::.: :..:. :. . .. : : :::.:
CCDS53 PLKASLEIEYQVLDGAGLDIDFHLASPEGKTLVFEQRKS-DGVHTVETEVGDYMFCFDNT
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE2 FSTFTHKTVYFDF---QVGEDPPLFPSENRVSALTQMESACVSIHEALKSVIDYQTHFRL
:::...:...:.. ..::. .:. . .: . ..... : .: . ..
CCDS53 FSTISEKVIFFELILDNMGEQAQ--EQEDWKKYITGTDILDMKLEDILDPIIKIASDVQI
120 130 140 150 160
180 190 200 210 220
pF1KE2 REAQGRSRAEDLNTRVAYWSVGEALILLVVSIGQVFLLKSFFSDKRTTTTRVGS
: : . ....:. :.
CCDS53 RLHLGIHQQHQVQTK-QKWAHTNSA
170 180 190
>>CCDS9840.1 TMED10 gene_id:10972|Hs108|chr14 (219 aa)
initn: 224 init1: 104 opt: 258 Z-score: 337.2 bits: 69.6 E(32554): 1.8e-12
Smith-Waterman score: 258; 27.5% identity (56.5% similar) in 207 aa overlap (16-216:10-216)
10 20 30 40 50
pF1KE2 MPRPGSAQRWAAVAGRWGCRLLALLLL-VPGPGGASEITFELPDNAKQCFYEDIAQGTKC
: : :::::: . :: . :.:.:: :...:. :.: .
CCDS98 MSGLSGPPARRGPFPLALLLLFLLGPRLVLAISFHLPINSRKCLREEIHKDLLV
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 TLEFQVI--TGGHYDVDCRLE--DPDGKVLYKEMKKQYDSFTFTASKNGTYKFCF-SNEF
: ... .:: . .:. : :..::.. .:.::. .. :: :.
CCDS98 TGAYEISDQSGGAGGLRSHLKITDSAGHILYSKEDATKGKFAFTTEDYDMFEVCFESKGT
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE2 STFTHKTVYFDFQVGEDPPLFPSENRVSALTQMESACVSIHEALKSVIDYQTHFRLREAQ
. . . : .:.. : . . .: : .: ... .:... .... :: .
CCDS98 GRIPDQLVILDMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEE
120 130 140 150 160 170
180 190 200 210 220
pF1KE2 GRSRAEDLNTRVAYWSVGEALILLVVSIGQVFLLKSFFSDKRTTTTRVGS
:. :. :::: :.:. . :. .. ::: :. ::. :.
CCDS98 MRDTNESTNTRVLYFSIFSMFCLIGLATWQVFYLRRFFKAKKLIE
180 190 200 210
>>CCDS12249.1 TMED1 gene_id:11018|Hs108|chr19 (227 aa)
initn: 372 init1: 246 opt: 256 Z-score: 334.4 bits: 69.1 E(32554): 2.6e-12
Smith-Waterman score: 362; 35.6% identity (58.4% similar) in 219 aa overlap (22-220:10-227)
10 20 30 40 50
pF1KE2 MPRPGSAQRWAAVAGRWGCRLLALLLLVPGP---GGAS-------EITFELPDNAKQCFY
::: ::.: : :::. :.:: :: . :::::
CCDS12 MMAAGAALALALWLLMP-PVEVGGAGPPPIQDGEFTFLLPAGRKQCFY
10 20 30 40
60 70 80 90 100 110
pF1KE2 EDIAQGTKCTLEFQVITGGHYDVDCRLEDPDGKVLYKEMKKQYDSFTFTASKNGTYKFCF
.. ... :.::: :. ::: ::.:.: .: .: .: : .. : ::.::
CCDS12 QSAPANASLETEYQVIGGAGLDVDFTLESPQGVLLVSESRKADGVHTVEPTEAGDYKLCF
50 60 70 80 90 100
120 130 140 150 160
pF1KE2 SNEFSTFTHKTVYF---------DFQV-GEDPPLFPSENRVSALTQMESACVSIHEALKS
.: :::...: :.: : .: : . : : . ... . ... :.
CCDS12 DNSFSTISEKLVFFELIFDSLQDDEEVEGWAEAVEPEEMLDVKMEDIKESIETMRTRLER
110 120 130 140 150 160
170 180 190 200 210 220
pF1KE2 VIDYQTHFRLREAQGRSRAEDLNTRVAYWSVGEALILLVVSIGQVFLLKSFFSDKRTTTT
:.. : .: ::. :. : :: .::. .. .::.:.. :: :: ::.::: . :
CCDS12 SIQMLTLLRAFEARDRNLQEGNLERVNFWSAVNVAVLLLVAVLQVCTLKRFFQDKRPVPT
170 180 190 200 210 220
pF1KE2 RVGS
224 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 16:43:20 2016 done: Tue Nov 8 16:43:20 2016
Total Scan time: 1.410 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]