Result of FASTA (omim) for
pFN21AE2591
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2591, 541 aa
1>>>pF1KE2591 541 - 541 aa - 541 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.9786+/-0.000434; mu= -3.7873+/- 0.027
mean_var=233.3894+/-46.489, 0's: 0 Z-trim(117.3): 6 B-trim: 0 in 0/55
Lambda= 0.083953
statistics sampled from 29190 (29194) to 29190 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.695), E-opt: 0.2 (0.342), width: 16
Scan time: 7.040
The best scores are: opt bits E(85289)
XP_011533527 (OMIM: 615906) PREDICTED: RING finger ( 649) 3462 432.7 1.6e-120
XP_016876232 (OMIM: 615906) PREDICTED: RING finger ( 649) 3462 432.7 1.6e-120
NP_078822 (OMIM: 615906) RING finger protein 219 [ ( 726) 3462 432.8 1.8e-120
>>XP_011533527 (OMIM: 615906) PREDICTED: RING finger pro (649 aa)
initn: 3461 init1: 3461 opt: 3462 Z-score: 2284.7 bits: 432.7 E(85289): 1.6e-120
Smith-Waterman score: 3462; 99.6% identity (99.6% similar) in 540 aa overlap (1-538:1-540)
10 20 30 40 50 60
pF1KE2 MLSHTVRKHLRKTRLELLHKEYEDEIDCLQKEVEELKSKNLSLESQIKTILDPLTLVQGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLSHTVRKHLRKTRLELLHKEYEDEIDCLQKEVEELKSKNLSLESQIKTILDPLTLVQGN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 QNEDKHLVTDNPSKINPETVAEWKKKLRTANEIYEKVKDDVDKLKEANKKLKLENGGLVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QNEDKHLVTDNPSKINPETVAEWKKKLRTANEIYEKVKDDVDKLKEANKKLKLENGGLVR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 ENLRLKAEVDNRSPQKFGRFAVAALQSKVEQYERETNRLKKALERSDKYIEELESQVAQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENLRLKAEVDNRSPQKFGRFAVAALQSKVEQYERETNRLKKALERSDKYIEELESQVAQL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 KNSSEEKEAMNSICQTALSADGKGSKGSEEDVVSKNQGDSARKQPGSSTSSSSHLAKPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KNSSEEKEAMNSICQTALSADGKGSKGSEEDVVSKNQGDSARKQPGSSTSSSSHLAKPSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 SRLCDTSSARQESTSKADLNCSKNKDLYQEQVEVMLDVTDTSMDTYLEREWGNKPSDCVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRLCDTSSARQESTSKADLNCSKNKDLYQEQVEVMLDVTDTSMDTYLEREWGNKPSDCVP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 YKDEELYDLPAPCTPLSLSCLQLSTPENRESSVVQAGGSKKHSNHLRKLVFDDFCDSSNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YKDEELYDLPAPCTPLSLSCLQLSTPENRESSVVQAGGSKKHSNHLRKLVFDDFCDSSNV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 SNKDSSEDDISRSENEKKSECFSSPKTGFWDCCSTSYAQNLDFESSEGNTIANSVGEISS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SNKDSSEDDISRSENEKKSECFSSPKTGFWDCCSTSYAQNLDFESSEGNTIANSVGEISS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 KLSEKSGLCLSKRLNSIRSFEMNRTRTSSEASMDAAYLDKISELDSMMSESDNSKSPCNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLSEKSGLCLSKRLNSIRSFEMNRTRTSSEASMDAAYLDKISELDSMMSESDNSKSPCNN
430 440 450 460 470 480
490 500 510 520 530
pF1KE2 GFKSLDLDGLSKSSQGSEFLEEPDKLEEKTELNLSKGSLTNDQLENGSEWKPTSFF--SP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
XP_011 GFKSLDLDGLSKSSQGSEFLEEPDKLEEKTELNLSKGSLTNDQLENGSEWKPTSFFLLSP
490 500 510 520 530 540
540
pF1KE2 LSI
XP_011 SDQEMNEDFSLHSSSCPVTNEIKPPSCLFQTEFSQGILLSSSHRLFEDQRFGSSLFKMSS
550 560 570 580 590 600
>>XP_016876232 (OMIM: 615906) PREDICTED: RING finger pro (649 aa)
initn: 3461 init1: 3461 opt: 3462 Z-score: 2284.7 bits: 432.7 E(85289): 1.6e-120
Smith-Waterman score: 3462; 99.6% identity (99.6% similar) in 540 aa overlap (1-538:1-540)
10 20 30 40 50 60
pF1KE2 MLSHTVRKHLRKTRLELLHKEYEDEIDCLQKEVEELKSKNLSLESQIKTILDPLTLVQGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLSHTVRKHLRKTRLELLHKEYEDEIDCLQKEVEELKSKNLSLESQIKTILDPLTLVQGN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 QNEDKHLVTDNPSKINPETVAEWKKKLRTANEIYEKVKDDVDKLKEANKKLKLENGGLVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QNEDKHLVTDNPSKINPETVAEWKKKLRTANEIYEKVKDDVDKLKEANKKLKLENGGLVR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 ENLRLKAEVDNRSPQKFGRFAVAALQSKVEQYERETNRLKKALERSDKYIEELESQVAQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENLRLKAEVDNRSPQKFGRFAVAALQSKVEQYERETNRLKKALERSDKYIEELESQVAQL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 KNSSEEKEAMNSICQTALSADGKGSKGSEEDVVSKNQGDSARKQPGSSTSSSSHLAKPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KNSSEEKEAMNSICQTALSADGKGSKGSEEDVVSKNQGDSARKQPGSSTSSSSHLAKPSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 SRLCDTSSARQESTSKADLNCSKNKDLYQEQVEVMLDVTDTSMDTYLEREWGNKPSDCVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRLCDTSSARQESTSKADLNCSKNKDLYQEQVEVMLDVTDTSMDTYLEREWGNKPSDCVP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 YKDEELYDLPAPCTPLSLSCLQLSTPENRESSVVQAGGSKKHSNHLRKLVFDDFCDSSNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YKDEELYDLPAPCTPLSLSCLQLSTPENRESSVVQAGGSKKHSNHLRKLVFDDFCDSSNV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 SNKDSSEDDISRSENEKKSECFSSPKTGFWDCCSTSYAQNLDFESSEGNTIANSVGEISS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SNKDSSEDDISRSENEKKSECFSSPKTGFWDCCSTSYAQNLDFESSEGNTIANSVGEISS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 KLSEKSGLCLSKRLNSIRSFEMNRTRTSSEASMDAAYLDKISELDSMMSESDNSKSPCNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLSEKSGLCLSKRLNSIRSFEMNRTRTSSEASMDAAYLDKISELDSMMSESDNSKSPCNN
430 440 450 460 470 480
490 500 510 520 530
pF1KE2 GFKSLDLDGLSKSSQGSEFLEEPDKLEEKTELNLSKGSLTNDQLENGSEWKPTSFF--SP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
XP_016 GFKSLDLDGLSKSSQGSEFLEEPDKLEEKTELNLSKGSLTNDQLENGSEWKPTSFFLLSP
490 500 510 520 530 540
540
pF1KE2 LSI
XP_016 SDQEMNEDFSLHSSSCPVTNEIKPPSCLFQTEFSQGILLSSSHRLFEDQRFGSSLFKMSS
550 560 570 580 590 600
>>NP_078822 (OMIM: 615906) RING finger protein 219 [Homo (726 aa)
initn: 3461 init1: 3461 opt: 3462 Z-score: 2283.9 bits: 432.8 E(85289): 1.8e-120
Smith-Waterman score: 3462; 99.6% identity (99.6% similar) in 540 aa overlap (1-538:78-617)
10 20 30
pF1KE2 MLSHTVRKHLRKTRLELLHKEYEDEIDCLQ
::::::::::::::::::::::::::::::
NP_078 NNSQCPACRVPITPENPCKEIIGGTSESEPMLSHTVRKHLRKTRLELLHKEYEDEIDCLQ
50 60 70 80 90 100
40 50 60 70 80 90
pF1KE2 KEVEELKSKNLSLESQIKTILDPLTLVQGNQNEDKHLVTDNPSKINPETVAEWKKKLRTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 KEVEELKSKNLSLESQIKTILDPLTLVQGNQNEDKHLVTDNPSKINPETVAEWKKKLRTA
110 120 130 140 150 160
100 110 120 130 140 150
pF1KE2 NEIYEKVKDDVDKLKEANKKLKLENGGLVRENLRLKAEVDNRSPQKFGRFAVAALQSKVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 NEIYEKVKDDVDKLKEANKKLKLENGGLVRENLRLKAEVDNRSPQKFGRFAVAALQSKVE
170 180 190 200 210 220
160 170 180 190 200 210
pF1KE2 QYERETNRLKKALERSDKYIEELESQVAQLKNSSEEKEAMNSICQTALSADGKGSKGSEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 QYERETNRLKKALERSDKYIEELESQVAQLKNSSEEKEAMNSICQTALSADGKGSKGSEE
230 240 250 260 270 280
220 230 240 250 260 270
pF1KE2 DVVSKNQGDSARKQPGSSTSSSSHLAKPSSSRLCDTSSARQESTSKADLNCSKNKDLYQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 DVVSKNQGDSARKQPGSSTSSSSHLAKPSSSRLCDTSSARQESTSKADLNCSKNKDLYQE
290 300 310 320 330 340
280 290 300 310 320 330
pF1KE2 QVEVMLDVTDTSMDTYLEREWGNKPSDCVPYKDEELYDLPAPCTPLSLSCLQLSTPENRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 QVEVMLDVTDTSMDTYLEREWGNKPSDCVPYKDEELYDLPAPCTPLSLSCLQLSTPENRE
350 360 370 380 390 400
340 350 360 370 380 390
pF1KE2 SSVVQAGGSKKHSNHLRKLVFDDFCDSSNVSNKDSSEDDISRSENEKKSECFSSPKTGFW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 SSVVQAGGSKKHSNHLRKLVFDDFCDSSNVSNKDSSEDDISRSENEKKSECFSSPKTGFW
410 420 430 440 450 460
400 410 420 430 440 450
pF1KE2 DCCSTSYAQNLDFESSEGNTIANSVGEISSKLSEKSGLCLSKRLNSIRSFEMNRTRTSSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 DCCSTSYAQNLDFESSEGNTIANSVGEISSKLSEKSGLCLSKRLNSIRSFEMNRTRTSSE
470 480 490 500 510 520
460 470 480 490 500 510
pF1KE2 ASMDAAYLDKISELDSMMSESDNSKSPCNNGFKSLDLDGLSKSSQGSEFLEEPDKLEEKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 ASMDAAYLDKISELDSMMSESDNSKSPCNNGFKSLDLDGLSKSSQGSEFLEEPDKLEEKT
530 540 550 560 570 580
520 530 540
pF1KE2 ELNLSKGSLTNDQLENGSEWKPTSFF--SPLSI
:::::::::::::::::::::::::: ::
NP_078 ELNLSKGSLTNDQLENGSEWKPTSFFLLSPSDQEMNEDFSLHSSSCPVTNEIKPPSCLFQ
590 600 610 620 630 640
541 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 16:42:46 2016 done: Tue Nov 8 16:42:47 2016
Total Scan time: 7.040 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]