Result of FASTA (ccds) for
pFN21AE2568
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2568, 265 aa
1>>>pF1KE2568 265 - 265 aa - 265 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6636+/-0.000815; mu= 12.7272+/- 0.049
mean_var=69.3465+/-13.807, 0's: 0 Z-trim(107.3): 16 B-trim: 0 in 0/49
Lambda= 0.154015
statistics sampled from 9455 (9465) to 9455 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.673), E-opt: 0.2 (0.291), width: 16
Scan time: 1.930
The best scores are: opt bits E(32554)
CCDS7473.1 LOXL4 gene_id:84171|Hs108|chr10 ( 756) 1926 437.0 1.8e-122
CCDS74527.1 LOXL3 gene_id:84695|Hs108|chr2 ( 608) 1360 311.2 1.1e-84
CCDS1953.1 LOXL3 gene_id:84695|Hs108|chr2 ( 753) 1360 311.2 1.3e-84
CCDS34864.1 LOXL2 gene_id:4017|Hs108|chr8 ( 774) 1320 302.4 6.4e-82
CCDS4129.1 LOX gene_id:4015|Hs108|chr5 ( 417) 765 178.9 4.9e-45
CCDS10253.1 LOXL1 gene_id:4016|Hs108|chr15 ( 574) 729 171.0 1.7e-42
>>CCDS7473.1 LOXL4 gene_id:84171|Hs108|chr10 (756 aa)
initn: 1926 init1: 1926 opt: 1926 Z-score: 2312.1 bits: 437.0 E(32554): 1.8e-122
Smith-Waterman score: 1926; 100.0% identity (100.0% similar) in 265 aa overlap (1-265:492-756)
10 20 30
pF1KE2 MSGVRCSGTELALQQCQRHGPVHCSHGGGR
::::::::::::::::::::::::::::::
CCDS74 ACRQLGLGFAIHAYKETWFWSGTPRAQEVVMSGVRCSGTELALQQCQRHGPVHCSHGGGR
470 480 490 500 510 520
40 50 60 70 80 90
pF1KE2 FLAGVSCMDSAPDLVMNAQLVQETAYLEDRPLSQLYCAHEENCLSKSADHMDWPYGYRRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 FLAGVSCMDSAPDLVMNAQLVQETAYLEDRPLSQLYCAHEENCLSKSADHMDWPYGYRRL
530 540 550 560 570 580
100 110 120 130 140 150
pF1KE2 LRFSTQIYNLGRTDFRPKTGRDSWVWHQCHRHYHSIEVFTHYDLLTLNGSKVAEGHKASF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 LRFSTQIYNLGRTDFRPKTGRDSWVWHQCHRHYHSIEVFTHYDLLTLNGSKVAEGHKASF
590 600 610 620 630 640
160 170 180 190 200 210
pF1KE2 CLEDTNCPTGLQRRYACANFGEQGVTVGCWDTYRHDIDCQWVDITDVGPGNYIFQVIVNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 CLEDTNCPTGLQRRYACANFGEQGVTVGCWDTYRHDIDCQWVDITDVGPGNYIFQVIVNP
650 660 670 680 690 700
220 230 240 250 260
pF1KE2 HYEVAESDFSNNMLQCRCKYDGHRVWLHNCHTGNSYPANAELSLEQEQRLRNNLI
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 HYEVAESDFSNNMLQCRCKYDGHRVWLHNCHTGNSYPANAELSLEQEQRLRNNLI
710 720 730 740 750
>>CCDS74527.1 LOXL3 gene_id:84695|Hs108|chr2 (608 aa)
initn: 1338 init1: 1238 opt: 1360 Z-score: 1633.9 bits: 311.2 E(32554): 1.1e-84
Smith-Waterman score: 1360; 65.8% identity (85.7% similar) in 266 aa overlap (1-265:342-607)
10 20
pF1KE2 MSGVRCSGTELALQQCQRHGP-VHCSHGGG
::::::.::::.:.:: .:: . :.. :
CCDS74 VACRQLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHHGTHITCKRTGT
320 330 340 350 360 370
30 40 50 60 70 80
pF1KE2 RFLAGVSCMDSAPDLVMNAQLVQETAYLEDRPLSQLYCAHEENCLSKSADHMDWPYGYRR
:: ::: : ..: ::.... :::::::.::::: .:::: :::::..:: .::::.::
CCDS74 RFTAGVICSETASDLLLHSALVQETAYIEDRPLHMLYCAAEENCLASSARSANWPYGHRR
380 390 400 410 420 430
90 100 110 120 130 140
pF1KE2 LLRFSTQIYNLGRTDFRPKTGRDSWVWHQCHRHYHSIEVFTHYDLLTLNGSKVAEGHKAS
:::::.::.::::.:::::.:: :::::.:: ::::...:::::.:: ::.:::::::::
CCDS74 LLRFSSQIHNLGRADFRPKAGRHSWVWHECHGHYHSMDIFTHYDILTPNGTKVAEGHKAS
440 450 460 470 480 490
150 160 170 180 190 200
pF1KE2 FCLEDTNCPTGLQRRYACANFGEQGVTVGCWDTYRHDIDCQWVDITDVGPGNYIFQVIVN
::::::.: ...:: ::::::::.:::::: :::::::::.::::: :::::.::..:
CCDS74 FCLEDTECQEDVSKRYECANFGEQGITVGCWDLYRHDIDCQWIDITDVKPGNYILQVVIN
500 510 520 530 540 550
210 220 230 240 250 260
pF1KE2 PHYEVAESDFSNNMLQCRCKYDGHRVWLHNCHTGNSYPANAELSLEQEQRLRNNLI
:..:::::::.:: ..: :::::::.:.:::: :... .:. .:. .: :
CCDS74 PNFEVAESDFTNNAMKCNCKYDGHRIWVHNCHIGDAFSEEANRRFERYPGQTSNQII
560 570 580 590 600
>>CCDS1953.1 LOXL3 gene_id:84695|Hs108|chr2 (753 aa)
initn: 1374 init1: 1238 opt: 1360 Z-score: 1632.5 bits: 311.2 E(32554): 1.3e-84
Smith-Waterman score: 1360; 65.8% identity (85.7% similar) in 266 aa overlap (1-265:487-752)
10 20
pF1KE2 MSGVRCSGTELALQQCQRHGP-VHCSHGGG
::::::.::::.:.:: .:: . :.. :
CCDS19 VACRQLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHHGTHITCKRTGT
460 470 480 490 500 510
30 40 50 60 70 80
pF1KE2 RFLAGVSCMDSAPDLVMNAQLVQETAYLEDRPLSQLYCAHEENCLSKSADHMDWPYGYRR
:: ::: : ..: ::.... :::::::.::::: .:::: :::::..:: .::::.::
CCDS19 RFTAGVICSETASDLLLHSALVQETAYIEDRPLHMLYCAAEENCLASSARSANWPYGHRR
520 530 540 550 560 570
90 100 110 120 130 140
pF1KE2 LLRFSTQIYNLGRTDFRPKTGRDSWVWHQCHRHYHSIEVFTHYDLLTLNGSKVAEGHKAS
:::::.::.::::.:::::.:: :::::.:: ::::...:::::.:: ::.:::::::::
CCDS19 LLRFSSQIHNLGRADFRPKAGRHSWVWHECHGHYHSMDIFTHYDILTPNGTKVAEGHKAS
580 590 600 610 620 630
150 160 170 180 190 200
pF1KE2 FCLEDTNCPTGLQRRYACANFGEQGVTVGCWDTYRHDIDCQWVDITDVGPGNYIFQVIVN
::::::.: ...:: ::::::::.:::::: :::::::::.::::: :::::.::..:
CCDS19 FCLEDTECQEDVSKRYECANFGEQGITVGCWDLYRHDIDCQWIDITDVKPGNYILQVVIN
640 650 660 670 680 690
210 220 230 240 250 260
pF1KE2 PHYEVAESDFSNNMLQCRCKYDGHRVWLHNCHTGNSYPANAELSLEQEQRLRNNLI
:..:::::::.:: ..: :::::::.:.:::: :... .:. .:. .: :
CCDS19 PNFEVAESDFTNNAMKCNCKYDGHRIWVHNCHIGDAFSEEANRRFERYPGQTSNQII
700 710 720 730 740 750
>>CCDS34864.1 LOXL2 gene_id:4017|Hs108|chr8 (774 aa)
initn: 1269 init1: 1236 opt: 1320 Z-score: 1584.2 bits: 302.4 E(32554): 6.4e-82
Smith-Waterman score: 1320; 64.8% identity (86.7% similar) in 264 aa overlap (1-263:506-769)
10 20
pF1KE2 MSGVRCSGTELALQQCQRHGP-VHCSHGGG
::::.::::::.: .:.. : : : .::
CCDS34 VCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHCRHDGEDVACPQGGV
480 490 500 510 520 530
30 40 50 60 70 80
pF1KE2 RFLAGVSCMDSAPDLVMNAQLVQETAYLEDRPLSQLYCAHEENCLSKSADHMDWPYGYRR
.. :::.: ..:::::.::..::.:.::::::. .: :: :::::: :: . : ::::
CCDS34 QYGAGVACSETAPDLVLNAEMVQQTTYLEDRPMFMLQCAMEENCLSASAAQTDPTTGYRR
540 550 560 570 580 590
90 100 110 120 130 140
pF1KE2 LLRFSTQIYNLGRTDFRPKTGRDSWVWHQCHRHYHSIEVFTHYDLLTLNGSKVAEGHKAS
:::::.::.: :..:::::.:: .:.::.:::::::.:::::::::.:::.:::::::::
CCDS34 LLRFSSQIHNNGQSDFRPKNGRHAWIWHDCHRHYHSMEVFTHYDLLNLNGTKVAEGHKAS
600 610 620 630 640 650
150 160 170 180 190 200
pF1KE2 FCLEDTNCPTGLQRRYACANFGEQGVTVGCWDTYRHDIDCQWVDITDVGPGNYIFQVIVN
::::::.: .:. : :::::.::.:.:::: ::::::::::::::: ::.:.:::..:
CCDS34 FCLEDTECEGDIQKNYECANFGDQGITMGCWDMYRHDIDCQWVDITDVPPGDYLFQVVIN
660 670 680 690 700 710
210 220 230 240 250 260
pF1KE2 PHYEVAESDFSNNMLQCRCKYDGHRVWLHNCHTGNSYPANAELSLEQEQRLRNNLI
:..::::::.:::...:: .:::::.:..::: :.:. ..: ..:. . : ::
CCDS34 PNFEVAESDYSNNIMKCRSRYDGHRIWMYNCHIGGSFSEETEKKFEHFSGLLNNQLSPQ
720 730 740 750 760 770
>>CCDS4129.1 LOX gene_id:4015|Hs108|chr5 (417 aa)
initn: 725 init1: 485 opt: 765 Z-score: 922.0 bits: 178.9 E(32554): 4.9e-45
Smith-Waterman score: 765; 49.5% identity (71.6% similar) in 218 aa overlap (28-240:196-412)
10 20 30 40 50
pF1KE2 MSGVRCSGTELALQQCQRHGPVHCSHGGGRFLAGVSC---MDSAPDLVMNAQLVQET
:::. : . . . :::: . .: .
CCDS41 MVGDDPYNPYKYSDDNPYYNYYDTYERPRPGGRYRPGYGTGYFQYGLPDLVADPYYIQAS
170 180 190 200 210 220
60 70 80 90 100 110
pF1KE2 AYLEDRPLSQLYCAHEENCLSKSADHMDW-PYGYRRLLRFSTQIYNLGRTDFRPKTGRDS
.:.. . .: :: :::::...: . : : .: :::: .. : : .:: :. : :
CCDS41 TYVQKMSMYNLRCAAEENCLASTAYRADVRDYDHRVLLRFPQRVKNQGTSDFLPSRPRYS
230 240 250 260 270 280
120 130 140 150 160 170
pF1KE2 WVWHQCHRHYHSIEVFTHYDLLTLNGSK-VAEGHKASFCLEDTNCPTGLQRRYACANFGE
: ::.::.::::.. :.::::: : .. ::::::::::::::.: : .::.::.
CCDS41 WEWHSCHQHYHSMDEFSHYDLLDANTQRRVAEGHKASFCLEDTSCDYGYHRRFACTAH-T
290 300 310 320 330 340
180 190 200 210 220 230
pF1KE2 QGVTVGCWDTYRHDIDCQWVDITDVGPGNYIFQVIVNPHYEVAESDFSNNMLQCRCKYDG
::.. ::.::: ::::::.::::: :::::..: ::: : : :::..::...: .: :
CCDS41 QGLSPGCYDTYGADIDCQWIDITDVKPGNYILKVSVNPSYLVPESDYTNNVVRCDIRYTG
350 360 370 380 390 400
240 250 260
pF1KE2 HRVWLHNCHTGNSYPANAELSLEQEQRLRNNLI
:... .:
CCDS41 HHAYASGCTISPY
410
>>CCDS10253.1 LOXL1 gene_id:4016|Hs108|chr15 (574 aa)
initn: 568 init1: 478 opt: 729 Z-score: 876.6 bits: 171.0 E(32554): 1.7e-42
Smith-Waterman score: 729; 52.2% identity (73.6% similar) in 201 aa overlap (42-240:370-569)
20 30 40 50 60 70
pF1KE2 ALQQCQRHGPVHCSHGGGRFLAGVSCMDSAPDLVMNAQLVQETAYLEDRPLSQLYCAHEE
:::: . . :: ..:.. : .: :: ::
CCDS10 PPPGGERNGAQQGRLSVGSVYRPNQNGRGLPDLVPDPNYVQASTYVQRAHLYSLRCAAEE
340 350 360 370 380 390
80 90 100 110 120 130
pF1KE2 NCLSKSADHMDWP-YGYRRLLRFSTQIYNLGRTDFRPKTGRDSWVWHQCHRHYHSIEVFT
.::...: . : : :::: .. : : .:: :. : .: ::.::.::::.. :.
CCDS10 KCLASTAYAPEATDYDVRVLLRFPQRVKNQGTADFLPNRPRHTWEWHSCHQHYHSMDEFS
400 410 420 430 440 450
140 150 160 170 180
pF1KE2 HYDLL-TLNGSKVAEGHKASFCLEDTNCPTGLQRRYACANFGEQGVTVGCWDTYRHDIDC
::::: . .:.::::::::::::::..: : .::::.. ::.. ::.::: ::::
CCDS10 HYDLLDAATGKKVAEGHKASFCLEDSTCDFGNLKRYACTSH-TQGLSPGCYDTYNADIDC
460 470 480 490 500 510
190 200 210 220 230 240
pF1KE2 QWVDITDVGPGNYIFQVIVNPHYEVAESDFSNNMLQCRCKYDGHRVWLHNCHTGNSYPAN
::.::::: :::::..: :::.: : ::::.::...: .: :. : ::
CCDS10 QWIDITDVQPGNYILKVHVNPKYIVLESDFTNNVVRCNIHYTGRYVSATNCKIVQS
520 530 540 550 560 570
250 260
pF1KE2 AELSLEQEQRLRNNLI
265 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 16:25:19 2016 done: Tue Nov 8 16:25:19 2016
Total Scan time: 1.930 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]