Result of FASTA (omim) for
pFN21AE2559
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2559, 147 aa
1>>>pF1KE2559 147 - 147 aa - 147 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1663+/-0.000285; mu= 12.5384+/- 0.018
mean_var=65.3495+/-13.212, 0's: 0 Z-trim(118.8): 12 B-trim: 1231 in 1/54
Lambda= 0.158655
statistics sampled from 32111 (32128) to 32111 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.759), E-opt: 0.2 (0.377), width: 16
Scan time: 5.420
The best scores are: opt bits E(85289)
XP_005273196 (OMIM: 609605) PREDICTED: microtubule ( 147) 969 229.7 1.3e-60
NP_001004343 (OMIM: 609605) microtubule-associated ( 147) 969 229.7 1.3e-60
NP_115903 (OMIM: 601242) microtubule-associated pr ( 121) 466 114.5 5.2e-26
XP_011527387 (OMIM: 601242) PREDICTED: microtubule ( 182) 466 114.6 7.3e-26
XP_011527385 (OMIM: 601242) PREDICTED: microtubule ( 223) 466 114.6 8.6e-26
XP_011527386 (OMIM: 601242) PREDICTED: microtubule ( 223) 466 114.6 8.6e-26
NP_073729 (OMIM: 609604) microtubule-associated pr ( 125) 443 109.2 2.1e-24
NP_852610 (OMIM: 601242) microtubule-associated pr ( 125) 399 99.2 2.2e-21
NP_113600 (OMIM: 607420) gamma-aminobutyric acid r ( 117) 309 78.5 3.3e-15
NP_009216 (OMIM: 607452) gamma-aminobutyric acid r ( 117) 306 77.9 5.4e-15
NP_009209 (OMIM: 605125) gamma-aminobutyric acid r ( 117) 296 75.6 2.6e-14
XP_005253401 (OMIM: 607420) PREDICTED: gamma-amino ( 146) 250 65.1 4.7e-11
>>XP_005273196 (OMIM: 609605) PREDICTED: microtubule-ass (147 aa)
initn: 969 init1: 969 opt: 969 Z-score: 1208.9 bits: 229.7 E(85289): 1.3e-60
Smith-Waterman score: 969; 100.0% identity (100.0% similar) in 147 aa overlap (1-147:1-147)
10 20 30 40 50 60
pF1KE2 MPPPQKIPSVRPFKQRKSLAIRQEEVAGIRAKFPNKIPVVVERYPRETFLPPLDKTKFLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MPPPQKIPSVRPFKQRKSLAIRQEEVAGIRAKFPNKIPVVVERYPRETFLPPLDKTKFLV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 PQELTMTQFLSIIRSRMVLRATEAFYLLVNNKSLVSMSATMAEIYRDYKDEDGFVYMTYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PQELTMTQFLSIIRSRMVLRATEAFYLLVNNKSLVSMSATMAEIYRDYKDEDGFVYMTYA
70 80 90 100 110 120
130 140
pF1KE2 SQETFGCLESAAPRDGSSLEDRPCNPL
:::::::::::::::::::::::::::
XP_005 SQETFGCLESAAPRDGSSLEDRPCNPL
130 140
>>NP_001004343 (OMIM: 609605) microtubule-associated pro (147 aa)
initn: 969 init1: 969 opt: 969 Z-score: 1208.9 bits: 229.7 E(85289): 1.3e-60
Smith-Waterman score: 969; 100.0% identity (100.0% similar) in 147 aa overlap (1-147:1-147)
10 20 30 40 50 60
pF1KE2 MPPPQKIPSVRPFKQRKSLAIRQEEVAGIRAKFPNKIPVVVERYPRETFLPPLDKTKFLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPPPQKIPSVRPFKQRKSLAIRQEEVAGIRAKFPNKIPVVVERYPRETFLPPLDKTKFLV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 PQELTMTQFLSIIRSRMVLRATEAFYLLVNNKSLVSMSATMAEIYRDYKDEDGFVYMTYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQELTMTQFLSIIRSRMVLRATEAFYLLVNNKSLVSMSATMAEIYRDYKDEDGFVYMTYA
70 80 90 100 110 120
130 140
pF1KE2 SQETFGCLESAAPRDGSSLEDRPCNPL
:::::::::::::::::::::::::::
NP_001 SQETFGCLESAAPRDGSSLEDRPCNPL
130 140
>>NP_115903 (OMIM: 601242) microtubule-associated protei (121 aa)
initn: 466 init1: 466 opt: 466 Z-score: 587.9 bits: 114.5 E(85289): 5.2e-26
Smith-Waterman score: 466; 59.2% identity (85.0% similar) in 120 aa overlap (7-126:1-120)
10 20 30 40 50 60
pF1KE2 MPPPQKIPSVRPFKQRKSLAIRQEEVAGIRAKFPNKIPVVVERYPRETFLPPLDKTKFLV
.:: ::::::.:.: : .:: :: . :.::::..::: : :: ::::::::
NP_115 MPSDRPFKQRRSFADRCKEVQQIRDQHPSKIPVIIERYKGEKQLPVLDKTKFLV
10 20 30 40 50
70 80 90 100 110 120
pF1KE2 PQELTMTQFLSIIRSRMVLRATEAFYLLVNNKSLVSMSATMAEIYRDYKDEDGFVYMTYA
:....:.....::: :. : :.::.::::..:.::.:. .:.::.. ::::::.::.::
NP_115 PDHVNMSELVKIIRRRLQLNPTQAFFLLVNQHSMVSVSTPIADIYEQEKDEDGFLYMVYA
60 70 80 90 100 110
130 140
pF1KE2 SQETFGCLESAAPRDGSSLEDRPCNPL
::::::
NP_115 SQETFGF
120
>>XP_011527387 (OMIM: 601242) PREDICTED: microtubule-ass (182 aa)
initn: 466 init1: 466 opt: 466 Z-score: 585.3 bits: 114.6 E(85289): 7.3e-26
Smith-Waterman score: 466; 59.2% identity (85.0% similar) in 120 aa overlap (7-126:62-181)
10 20 30
pF1KE2 MPPPQKIPSVRPFKQRKSLAIRQEEVAGIRAKFPNK
.:: ::::::.:.: : .:: :: . :.:
XP_011 REARSPRSPQTADTSPRPRAPACAPSRARAMPSDRPFKQRRSFADRCKEVQQIRDQHPSK
40 50 60 70 80 90
40 50 60 70 80 90
pF1KE2 IPVVVERYPRETFLPPLDKTKFLVPQELTMTQFLSIIRSRMVLRATEAFYLLVNNKSLVS
:::..::: : :: :::::::::....:.....::: :. : :.::.::::..:.::
XP_011 IPVIIERYKGEKQLPVLDKTKFLVPDHVNMSELVKIIRRRLQLNPTQAFFLLVNQHSMVS
100 110 120 130 140 150
100 110 120 130 140
pF1KE2 MSATMAEIYRDYKDEDGFVYMTYASQETFGCLESAAPRDGSSLEDRPCNPL
.:. .:.::.. ::::::.::.::::::::
XP_011 VSTPIADIYEQEKDEDGFLYMVYASQETFGF
160 170 180
>>XP_011527385 (OMIM: 601242) PREDICTED: microtubule-ass (223 aa)
initn: 466 init1: 466 opt: 466 Z-score: 584.0 bits: 114.6 E(85289): 8.6e-26
Smith-Waterman score: 466; 59.2% identity (85.0% similar) in 120 aa overlap (7-126:103-222)
10 20 30
pF1KE2 MPPPQKIPSVRPFKQRKSLAIRQEEVAGIRAKFPNK
.:: ::::::.:.: : .:: :: . :.:
XP_011 REARSPRSPQTADTSPRPRAPACAPSRARAMPSDRPFKQRRSFADRCKEVQQIRDQHPSK
80 90 100 110 120 130
40 50 60 70 80 90
pF1KE2 IPVVVERYPRETFLPPLDKTKFLVPQELTMTQFLSIIRSRMVLRATEAFYLLVNNKSLVS
:::..::: : :: :::::::::....:.....::: :. : :.::.::::..:.::
XP_011 IPVIIERYKGEKQLPVLDKTKFLVPDHVNMSELVKIIRRRLQLNPTQAFFLLVNQHSMVS
140 150 160 170 180 190
100 110 120 130 140
pF1KE2 MSATMAEIYRDYKDEDGFVYMTYASQETFGCLESAAPRDGSSLEDRPCNPL
.:. .:.::.. ::::::.::.::::::::
XP_011 VSTPIADIYEQEKDEDGFLYMVYASQETFGF
200 210 220
>>XP_011527386 (OMIM: 601242) PREDICTED: microtubule-ass (223 aa)
initn: 466 init1: 466 opt: 466 Z-score: 584.0 bits: 114.6 E(85289): 8.6e-26
Smith-Waterman score: 466; 59.2% identity (85.0% similar) in 120 aa overlap (7-126:103-222)
10 20 30
pF1KE2 MPPPQKIPSVRPFKQRKSLAIRQEEVAGIRAKFPNK
.:: ::::::.:.: : .:: :: . :.:
XP_011 REARSPRSPQTADTSPRPRAPACAPSRARAMPSDRPFKQRRSFADRCKEVQQIRDQHPSK
80 90 100 110 120 130
40 50 60 70 80 90
pF1KE2 IPVVVERYPRETFLPPLDKTKFLVPQELTMTQFLSIIRSRMVLRATEAFYLLVNNKSLVS
:::..::: : :: :::::::::....:.....::: :. : :.::.::::..:.::
XP_011 IPVIIERYKGEKQLPVLDKTKFLVPDHVNMSELVKIIRRRLQLNPTQAFFLLVNQHSMVS
140 150 160 170 180 190
100 110 120 130 140
pF1KE2 MSATMAEIYRDYKDEDGFVYMTYASQETFGCLESAAPRDGSSLEDRPCNPL
.:. .:.::.. ::::::.::.::::::::
XP_011 VSTPIADIYEQEKDEDGFLYMVYASQETFGF
200 210 220
>>NP_073729 (OMIM: 609604) microtubule-associated protei (125 aa)
initn: 443 init1: 443 opt: 443 Z-score: 559.2 bits: 109.2 E(85289): 2.1e-24
Smith-Waterman score: 443; 55.0% identity (84.2% similar) in 120 aa overlap (7-126:1-120)
10 20 30 40 50 60
pF1KE2 MPPPQKIPSVRPFKQRKSLAIRQEEVAGIRAKFPNKIPVVVERYPRETFLPPLDKTKFLV
.:: . ::::... : :.: :: . :.::::..::: : :: ::::::::
NP_073 MPSEKTFKQRRTFEQRVEDVRLIREQHPTKIPVIIERYKGEKQLPVLDKTKFLV
10 20 30 40 50
70 80 90 100 110 120
pF1KE2 PQELTMTQFLSIIRSRMVLRATEAFYLLVNNKSLVSMSATMAEIYRDYKDEDGFVYMTYA
:....:.....::: :. : :..::.::::..:.::.:. ..:.:.. ::::::.::.::
NP_073 PDHVNMSELIKIIRRRLQLNANQAFFLLVNGHSMVSVSTPISEVYESEKDEDGFLYMVYA
60 70 80 90 100 110
130 140
pF1KE2 SQETFGCLESAAPRDGSSLEDRPCNPL
::::::
NP_073 SQETFGMKLSV
120
>>NP_852610 (OMIM: 601242) microtubule-associated protei (125 aa)
initn: 399 init1: 399 opt: 399 Z-score: 504.8 bits: 99.2 E(85289): 2.2e-21
Smith-Waterman score: 399; 57.9% identity (84.1% similar) in 107 aa overlap (20-126:18-124)
10 20 30 40 50 60
pF1KE2 MPPPQKIPSVRPFKQRKSLAIRQEEVAGIRAKFPNKIPVVVERYPRETFLPPLDKTKFLV
: : .:: :: . :.::::..::: : :: ::::::::
NP_852 MKMRFFSSPCGKAAVDPADRCKEVQQIRDQHPSKIPVIIERYKGEKQLPVLDKTKFLV
10 20 30 40 50
70 80 90 100 110 120
pF1KE2 PQELTMTQFLSIIRSRMVLRATEAFYLLVNNKSLVSMSATMAEIYRDYKDEDGFVYMTYA
:....:.....::: :. : :.::.::::..:.::.:. .:.::.. ::::::.::.::
NP_852 PDHVNMSELVKIIRRRLQLNPTQAFFLLVNQHSMVSVSTPIADIYEQEKDEDGFLYMVYA
60 70 80 90 100 110
130 140
pF1KE2 SQETFGCLESAAPRDGSSLEDRPCNPL
::::::
NP_852 SQETFGF
120
>>NP_113600 (OMIM: 607420) gamma-aminobutyric acid recep (117 aa)
initn: 308 init1: 142 opt: 309 Z-score: 393.9 bits: 78.5 E(85289): 3.3e-15
Smith-Waterman score: 309; 39.5% identity (76.3% similar) in 114 aa overlap (13-126:5-116)
10 20 30 40 50 60
pF1KE2 MPPPQKIPSVRPFKQRKSLAIRQEEVAGIRAKFPNKIPVVVERYPRETFLPPLDKTKFLV
.:. . . :..: :: :.:...::.::. :. .: ::: :.::
NP_113 MKFQYKEDHPFEYRKKEGEKIRKKYPDRVPVIVEKAPKAR-VPDLDKRKYLV
10 20 30 40 50
70 80 90 100 110 120
pF1KE2 PQELTMTQFLSIIRSRMVLRATEAFYLLVNNKSLVSMSATMAEIYRDYKDEDGFVYMTYA
:..::. :: .::.:. :: .:....::: .. ::::...:.: ..:: :.:..:.
NP_113 PSDLTVGQFYFLIRKRIHLRPEDALFFFVNN-TIPPTSATMGQLYEDNHEEDYFLYVAYS
60 70 80 90 100 110
130 140
pF1KE2 SQETFGCLESAAPRDGSSLEDRPCNPL
.. ..:
NP_113 DESVYGK
>>NP_009216 (OMIM: 607452) gamma-aminobutyric acid recep (117 aa)
initn: 303 init1: 115 opt: 306 Z-score: 390.2 bits: 77.9 E(85289): 5.4e-15
Smith-Waterman score: 306; 43.0% identity (78.1% similar) in 114 aa overlap (13-126:5-116)
10 20 30 40 50 60
pF1KE2 MPPPQKIPSVRPFKQRKSLAIRQEEVAGIRAKFPNKIPVVVERYPRETFLPPLDKTKFLV
::. .:: : : : ::::.:...::.::. .. .:: :.::
NP_009 MKWMFKEDHSLEHRCVESAKIRAKYPDRVPVIVEKVSGSQIVD-IDKRKYLV
10 20 30 40 50
70 80 90 100 110 120
pF1KE2 PQELTMTQFLSIIRSRMVLRATEAFYLLVNNKSLVSMSATMAEIYRDYKDEDGFVYMTYA
:...:..::. :::.:. : . .:..:.:. :.. . : ::...:. ::::::.:..:.
NP_009 PSDITVAQFMWIIRKRIQLPSEKAIFLFVD-KTVPQSSLTMGQLYEKEKDEDGFLYVAYS
60 70 80 90 100 110
130 140
pF1KE2 SQETFGCLESAAPRDGSSLEDRPCNPL
...:::
NP_009 GENTFGF
147 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 21:30:55 2016 done: Fri Nov 4 21:30:56 2016
Total Scan time: 5.420 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]