Result of FASTA (omim) for
pFN21AE2550
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2550, 383 aa
1>>>pF1KE2550 383 - 383 aa - 383 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8782+/-0.000341; mu= 19.5566+/- 0.021
mean_var=76.4028+/-15.537, 0's: 0 Z-trim(114.5): 135 B-trim: 21 in 1/57
Lambda= 0.146730
statistics sampled from 24215 (24369) to 24215 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.665), E-opt: 0.2 (0.286), width: 16
Scan time: 5.550
The best scores are: opt bits E(85289)
NP_000238 (OMIM: 600169) MHC class I polypeptide-r ( 383) 2623 564.8 1.2e-160
NP_001170990 (OMIM: 600169) MHC class I polypeptid ( 332) 2134 461.2 1.6e-129
NP_005922 (OMIM: 602436) MHC class I polypeptide-r ( 383) 2108 455.8 8e-128
NP_001276089 (OMIM: 602436) MHC class I polypeptid ( 351) 1938 419.7 5.1e-117
NP_001276082 (OMIM: 600169) MHC class I polypeptid ( 235) 1467 319.9 3.9e-87
NP_001276081 (OMIM: 600169) MHC class I polypeptid ( 235) 1467 319.9 3.9e-87
NP_001276090 (OMIM: 602436) MHC class I polypeptid ( 340) 1283 281.1 2.7e-75
NP_001276083 (OMIM: 600169) MHC class I polypeptid ( 194) 1030 227.3 2.4e-59
NP_001229971 (OMIM: 142840,177900,609423) HLA clas ( 366) 520 119.6 1.2e-26
XP_016866297 (OMIM: 143010) PREDICTED: HLA class I ( 399) 520 119.6 1.3e-26
XP_016866296 (OMIM: 143010) PREDICTED: HLA class I ( 399) 520 119.6 1.3e-26
NP_002108 (OMIM: 142840,177900,609423) HLA class I ( 366) 517 118.9 1.9e-26
NP_005505 (OMIM: 106300,142830,608579) major histo ( 362) 510 117.5 5.2e-26
NP_005507 (OMIM: 143010) HLA class I histocompatib ( 358) 507 116.8 8e-26
XP_016866298 (OMIM: 143010) PREDICTED: HLA class I ( 359) 507 116.8 8e-26
NP_002107 (OMIM: 142800,608579) HLA class I histoc ( 365) 507 116.8 8.1e-26
NP_001229687 (OMIM: 142800,608579) HLA class I his ( 365) 498 114.9 3e-25
XP_011512859 (OMIM: 106300,142830,608579) PREDICTE ( 323) 491 113.4 7.8e-25
NP_002118 (OMIM: 142871,600807) HLA class I histoc ( 338) 488 112.8 1.2e-24
XP_016866305 (OMIM: 142871,600807) PREDICTED: HLA ( 343) 488 112.8 1.3e-24
XP_011512866 (OMIM: 143110) PREDICTED: HLA class I ( 343) 488 112.8 1.3e-24
NP_061823 (OMIM: 143110) HLA class I histocompatib ( 346) 488 112.8 1.3e-24
XP_016866302 (OMIM: 143110) PREDICTED: HLA class I ( 388) 488 112.8 1.4e-24
XP_016866301 (OMIM: 143110) PREDICTED: HLA class I ( 420) 488 112.9 1.5e-24
XP_016866300 (OMIM: 143110) PREDICTED: HLA class I ( 431) 488 112.9 1.5e-24
XP_016866299 (OMIM: 143110) PREDICTED: HLA class I ( 435) 488 112.9 1.5e-24
NP_001091949 (OMIM: 143110) HLA class I histocompa ( 442) 488 112.9 1.5e-24
NP_001287678 (OMIM: 104300,176100,176200,235200,61 ( 337) 479 110.9 4.7e-24
NP_000401 (OMIM: 104300,176100,176200,235200,61263 ( 348) 479 110.9 4.8e-24
XP_011512845 (OMIM: 104300,176100,176200,235200,61 ( 348) 479 110.9 4.8e-24
XP_016885777 (OMIM: 142800,608579) PREDICTED: HLA ( 362) 475 110.0 8.8e-24
XP_005275388 (OMIM: 142800,608579) PREDICTED: HLA ( 391) 475 110.1 9.3e-24
NP_620578 (OMIM: 104300,176100,176200,235200,61263 ( 325) 469 108.7 2e-23
NP_001522 (OMIM: 600764) major histocompatibility ( 341) 468 108.5 2.4e-23
NP_620576 (OMIM: 104300,176100,176200,235200,61263 ( 260) 403 94.7 2.7e-19
XP_011507765 (OMIM: 600764) PREDICTED: major histo ( 254) 387 91.3 2.8e-18
NP_001176 (OMIM: 194460) zinc-alpha-2-glycoprotein ( 298) 374 88.6 2.1e-17
XP_016866304 (OMIM: 143110) PREDICTED: HLA class I ( 228) 361 85.7 1.2e-16
XP_016866303 (OMIM: 143110) PREDICTED: HLA class I ( 324) 361 85.9 1.5e-16
NP_004098 (OMIM: 601437) IgG receptor FcRn large s ( 365) 332 79.8 1.1e-14
NP_001129491 (OMIM: 601437) IgG receptor FcRn larg ( 365) 332 79.8 1.1e-14
NP_001181928 (OMIM: 600764) major histocompatibili ( 296) 309 74.8 2.9e-13
NP_620579 (OMIM: 104300,176100,176200,235200,61263 ( 168) 289 70.4 3.6e-12
NP_620573 (OMIM: 104300,176100,176200,235200,61263 ( 256) 289 70.5 4.9e-12
NP_620577 (OMIM: 104300,176100,176200,235200,61263 ( 246) 264 65.2 1.9e-10
NP_620575 (OMIM: 104300,176100,176200,235200,61263 ( 334) 264 65.3 2.3e-10
NP_620572 (OMIM: 104300,176100,176200,235200,61263 ( 242) 261 64.6 2.9e-10
XP_016866307 (OMIM: 142871,600807) PREDICTED: HLA ( 246) 261 64.6 2.9e-10
XP_016866306 (OMIM: 142871,600807) PREDICTED: HLA ( 246) 261 64.6 2.9e-10
NP_001091948 (OMIM: 143110) HLA class I histocompa ( 254) 242 60.6 4.8e-09
>>NP_000238 (OMIM: 600169) MHC class I polypeptide-relat (383 aa)
initn: 2623 init1: 2623 opt: 2623 Z-score: 3005.0 bits: 564.8 E(85289): 1.2e-160
Smith-Waterman score: 2623; 99.7% identity (100.0% similar) in 382 aa overlap (1-382:1-382)
10 20 30 40 50 60
pF1KE2 MGLGPVFLLLAGIFPFAPPGAAAEPHSLRYNLTVLSWDGSVQSGFLTEVHLDGQPFLRCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MGLGPVFLLLAGIFPFAPPGAAAEPHSLRYNLTVLSWDGSVQSGFLTEVHLDGQPFLRCD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 RQKCRAKPQGQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIKDQKEGLHSLQEIRVCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RQKCRAKPQGQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIKDQKEGLHSLQEIRVCE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 IHEDNSTRSSQHFYYDGELFLSQNLETEEWTMPQSSRAQTLAMNVRNFLKEDAMKTKTHY
:::::::::::::::::::::::::::.::::::::::::::::::::::::::::::::
NP_000 IHEDNSTRSSQHFYYDGELFLSQNLETKEWTMPQSSRAQTLAMNVRNFLKEDAMKTKTHY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 HAMHADCLQELRRYLKSGVVLRRTVPPMVNVTRSEASEGNITVTCRASGFYPWNITLSWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 HAMHADCLQELRRYLKSGVVLRRTVPPMVNVTRSEASEGNITVTCRASGFYPWNITLSWR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 QDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSGNHSTHPVPSGKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSGNHSTHPVPSGKV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 LVLQSHWQTFHVSAVAAAAIFVIIIFYVRCCKKKTSAAEGPELVSLQVLDQHPVGTSDHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LVLQSHWQTFHVSAVAAAAIFVIIIFYVRCCKKKTSAAEGPELVSLQVLDQHPVGTSDHR
310 320 330 340 350 360
370 380
pF1KE2 DATQLGFQPLMSDLGSTGSTEGT
::::::::::::::::::::::
NP_000 DATQLGFQPLMSDLGSTGSTEGA
370 380
>>NP_001170990 (OMIM: 600169) MHC class I polypeptide-re (332 aa)
initn: 2128 init1: 2128 opt: 2134 Z-score: 2446.4 bits: 461.2 E(85289): 1.6e-129
Smith-Waterman score: 2134; 93.9% identity (97.0% similar) in 330 aa overlap (1-330:1-329)
10 20 30 40 50 60
pF1KE2 MGLGPVFLLLAGIFPFAPPGAAAEPHSLRYNLTVLSWDGSVQSGFLTEVHLDGQPFLRCD
::::::::::::::::::::::::::::::::::::::::::::::.::::::::::: :
NP_001 MGLGPVFLLLAGIFPFAPPGAAAEPHSLRYNLTVLSWDGSVQSGFLAEVHLDGQPFLRYD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 RQKCRAKPQGQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIKDQKEGLHSLQEIRVCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RQKCRAKPQGQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIKDQKEGLHSLQEIRVCE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 IHEDNSTRSSQHFYYDGELFLSQNLETEEWTMPQSSRAQTLAMNVRNFLKEDAMKTKTHY
:::::::::::::::::::::::::::::::.::::::::::::::::::::::::::::
NP_001 IHEDNSTRSSQHFYYDGELFLSQNLETEEWTVPQSSRAQTLAMNVRNFLKEDAMKTKTHY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 HAMHADCLQELRRYLKSGVVLRRTVPPMVNVTRSEASEGNITVTCRASGFYPWNITLSWR
:::::::::::::::.::::::::::::::::::::::::::::::::.::: :: :.::
NP_001 HAMHADCLQELRRYLESGVVLRRTVPPMVNVTRSEASEGNITVTCRASSFYPRNIILTWR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 QDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSGNHSTHPVPSGKV
:::::::::::::::::::::::::::::::::.::::::::::::::::::::::::::
NP_001 QDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICRGEEQRFTCYMEHSGNHSTHPVPSGKV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 LVLQSHWQTFHVSAVAAAAIFVIIIFYVRCCKKKTSAAEGPELVSLQVLDQHPVGTSDHR
:::::::::::::::::. . . .: :
NP_001 LVLQSHWQTFHVSAVAAGCCY-FCYYYFLCPLL
310 320 330
>>NP_005922 (OMIM: 602436) MHC class I polypeptide-relat (383 aa)
initn: 2108 init1: 2108 opt: 2108 Z-score: 2415.9 bits: 455.8 E(85289): 8e-128
Smith-Waterman score: 2108; 82.8% identity (91.4% similar) in 383 aa overlap (1-383:1-383)
10 20 30 40 50 60
pF1KE2 MGLGPVFLLLAGIFPFAPPGAAAEPHSLRYNLTVLSWDGSVQSGFLTEVHLDGQPFLRCD
:::: :.:.:: ::::::.:::::::::::: ::: :::::::::.: ::::::::: :
NP_005 MGLGRVLLFLAVAFPFAPPAAAAEPHSLRYNLMVLSQDGSVQSGFLAEGHLDGQPFLRYD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 RQKCRAKPQGQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIKDQKEGLHSLQEIRVCE
::: ::::::::::.::: :::: ::.::: ::.::: ::.:::::: ::::::::::::
NP_005 RQKRRAKPQGQWAENVLGAKTWDTETEDLTENGQDLRRTLTHIKDQKGGLHSLQEIRVCE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 IHEDNSTRSSQHFYYDGELFLSQNLETEEWTMPQSSRAQTLAMNVRNFLKEDAMKTKTHY
::::.:::.:.::::::::::::::::.: :.::::::::::::: :: :::::::::::
NP_005 IHEDSSTRGSRHFYYDGELFLSQNLETQESTVPQSSRAQTLAMNVTNFWKEDAMKTKTHY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 HAMHADCLQELRRYLKSGVVLRRTVPPMVNVTRSEASEGNITVTCRASGFYPWNITLSWR
.::.:::::.:.:::::::..::::::::::: ::.::::::::::::.::: ::::.::
NP_005 RAMQADCLQKLQRYLKSGVAIRRTVPPMVNVTCSEVSEGNITVTCRASSFYPRNITLTWR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 QDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSGNHSTHPVPSGKV
::::::::.::::::::::::::::::::::: :::::::::::::::::.::::::::.
NP_005 QDGVSLSHNTQQWGDVLPDGNGTYQTWVATRIRQGEEQRFTCYMEHSGNHGTHPVPSGKA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 LVLQSHWQTFHVSAVAAAAIFVIIIFYVRCCKKKTSAAEGPELVSLQVLDQHPVGTSDHR
:::::. : ..: . .:::. : :::::::::::::::::::::::::::.:::
NP_005 LVLQSQRTDFPYVSAAMPCFVIIIILCVPCCKKKTSAAEGPELVSLQVLDQHPVGTGDHR
310 320 330 340 350 360
370 380
pF1KE2 DATQLGFQPLMSDLGSTGSTEGT
::.::::::::: :::::::::
NP_005 DAAQLGFQPLMSATGSTGSTEGT
370 380
>>NP_001276089 (OMIM: 602436) MHC class I polypeptide-re (351 aa)
initn: 1938 init1: 1938 opt: 1938 Z-score: 2221.9 bits: 419.7 E(85289): 5.1e-117
Smith-Waterman score: 1938; 83.1% identity (91.7% similar) in 350 aa overlap (34-383:2-351)
10 20 30 40 50 60
pF1KE2 GPVFLLLAGIFPFAPPGAAAEPHSLRYNLTVLSWDGSVQSGFLTEVHLDGQPFLRCDRQK
::: :::::::::.: ::::::::: ::::
NP_001 MVLSQDGSVQSGFLAEGHLDGQPFLRYDRQK
10 20 30
70 80 90 100 110 120
pF1KE2 CRAKPQGQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIKDQKEGLHSLQEIRVCEIHE
::::::::::.::: :::: ::.::: ::.::: ::.:::::: :::::::::::::::
NP_001 RRAKPQGQWAENVLGAKTWDTETEDLTENGQDLRRTLTHIKDQKGGLHSLQEIRVCEIHE
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE2 DNSTRSSQHFYYDGELFLSQNLETEEWTMPQSSRAQTLAMNVRNFLKEDAMKTKTHYHAM
:.:::.:.::::::::::::::::.: :.::::::::::::: :: :::::::::::.::
NP_001 DSSTRGSRHFYYDGELFLSQNLETQESTVPQSSRAQTLAMNVTNFWKEDAMKTKTHYRAM
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE2 HADCLQELRRYLKSGVVLRRTVPPMVNVTRSEASEGNITVTCRASGFYPWNITLSWRQDG
.:::::.:.:::::::..::::::::::: ::.::::::::::::.::: ::::.:::::
NP_001 QADCLQKLQRYLKSGVAIRRTVPPMVNVTCSEVSEGNITVTCRASSFYPRNITLTWRQDG
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE2 VSLSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSGNHSTHPVPSGKVLVL
:::::.::::::::::::::::::::::: :::::::::::::::::.::::::::.:::
NP_001 VSLSHNTQQWGDVLPDGNGTYQTWVATRIRQGEEQRFTCYMEHSGNHGTHPVPSGKALVL
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE2 QSHWQTFHVSAVAAAAIFVIIIFYVRCCKKKTSAAEGPELVSLQVLDQHPVGTSDHRDAT
::. : ..: . .:::. : :::::::::::::::::::::::::::.:::::.
NP_001 QSQRTDFPYVSAAMPCFVIIIILCVPCCKKKTSAAEGPELVSLQVLDQHPVGTGDHRDAA
280 290 300 310 320 330
370 380
pF1KE2 QLGFQPLMSDLGSTGSTEGT
::::::::: :::::::::
NP_001 QLGFQPLMSATGSTGSTEGT
340 350
>>NP_001276082 (OMIM: 600169) MHC class I polypeptide-re (235 aa)
initn: 1461 init1: 1461 opt: 1467 Z-score: 1685.2 bits: 319.9 E(85289): 3.9e-87
Smith-Waterman score: 1467; 92.3% identity (96.1% similar) in 233 aa overlap (98-330:1-232)
70 80 90 100 110 120
pF1KE2 PQGQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIKDQKEGLHSLQEIRVCEIHEDNST
::::::::::::::::::::::::::::::
NP_001 MTLAHIKDQKEGLHSLQEIRVCEIHEDNST
10 20 30
130 140 150 160 170 180
pF1KE2 RSSQHFYYDGELFLSQNLETEEWTMPQSSRAQTLAMNVRNFLKEDAMKTKTHYHAMHADC
::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::
NP_001 RSSQHFYYDGELFLSQNLETEEWTVPQSSRAQTLAMNVRNFLKEDAMKTKTHYHAMHADC
40 50 60 70 80 90
190 200 210 220 230 240
pF1KE2 LQELRRYLKSGVVLRRTVPPMVNVTRSEASEGNITVTCRASGFYPWNITLSWRQDGVSLS
::::::::.::::::::::::::::::::::::::::::::.::: :: :.:::::::::
NP_001 LQELRRYLESGVVLRRTVPPMVNVTRSEASEGNITVTCRASSFYPRNIILTWRQDGVSLS
100 110 120 130 140 150
250 260 270 280 290 300
pF1KE2 HDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSGNHSTHPVPSGKVLVLQSHW
::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::
NP_001 HDTQQWGDVLPDGNGTYQTWVATRICRGEEQRFTCYMEHSGNHSTHPVPSGKVLVLQSHW
160 170 180 190 200 210
310 320 330 340 350 360
pF1KE2 QTFHVSAVAAAAIFVIIIFYVRCCKKKTSAAEGPELVSLQVLDQHPVGTSDHRDATQLGF
::::::::::. . . .: :
NP_001 QTFHVSAVAAGCCY-FCYYYFLCPLL
220 230
>>NP_001276081 (OMIM: 600169) MHC class I polypeptide-re (235 aa)
initn: 1461 init1: 1461 opt: 1467 Z-score: 1685.2 bits: 319.9 E(85289): 3.9e-87
Smith-Waterman score: 1467; 92.3% identity (96.1% similar) in 233 aa overlap (98-330:1-232)
70 80 90 100 110 120
pF1KE2 PQGQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIKDQKEGLHSLQEIRVCEIHEDNST
::::::::::::::::::::::::::::::
NP_001 MTLAHIKDQKEGLHSLQEIRVCEIHEDNST
10 20 30
130 140 150 160 170 180
pF1KE2 RSSQHFYYDGELFLSQNLETEEWTMPQSSRAQTLAMNVRNFLKEDAMKTKTHYHAMHADC
::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::
NP_001 RSSQHFYYDGELFLSQNLETEEWTVPQSSRAQTLAMNVRNFLKEDAMKTKTHYHAMHADC
40 50 60 70 80 90
190 200 210 220 230 240
pF1KE2 LQELRRYLKSGVVLRRTVPPMVNVTRSEASEGNITVTCRASGFYPWNITLSWRQDGVSLS
::::::::.::::::::::::::::::::::::::::::::.::: :: :.:::::::::
NP_001 LQELRRYLESGVVLRRTVPPMVNVTRSEASEGNITVTCRASSFYPRNIILTWRQDGVSLS
100 110 120 130 140 150
250 260 270 280 290 300
pF1KE2 HDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSGNHSTHPVPSGKVLVLQSHW
::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::
NP_001 HDTQQWGDVLPDGNGTYQTWVATRICRGEEQRFTCYMEHSGNHSTHPVPSGKVLVLQSHW
160 170 180 190 200 210
310 320 330 340 350 360
pF1KE2 QTFHVSAVAAAAIFVIIIFYVRCCKKKTSAAEGPELVSLQVLDQHPVGTSDHRDATQLGF
::::::::::. . . .: :
NP_001 QTFHVSAVAAGCCY-FCYYYFLCPLL
220 230
>>NP_001276090 (OMIM: 602436) MHC class I polypeptide-re (340 aa)
initn: 1844 init1: 1283 opt: 1283 Z-score: 1472.7 bits: 281.1 E(85289): 2.7e-75
Smith-Waterman score: 1760; 73.1% identity (80.7% similar) in 383 aa overlap (1-383:1-340)
10 20 30 40 50 60
pF1KE2 MGLGPVFLLLAGIFPFAPPGAAAEPHSLRYNLTVLSWDGSVQSGFLTEVHLDGQPFLRCD
:::: :.:.:: ::::::.:::::::::::: ::: :::::::::.: ::::::::: :
NP_001 MGLGRVLLFLAVAFPFAPPAAAAEPHSLRYNLMVLSQDGSVQSGFLAEGHLDGQPFLRYD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 RQKCRAKPQGQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIKDQKEGLHSLQEIRVCE
::: ::::::::::.::: :::: ::.::: ::.::: ::.:::::: :.
NP_001 RQKRRAKPQGQWAENVLGAKTWDTETEDLTENGQDLRRTLTHIKDQK-GV----------
70 80 90 100
130 140 150 160 170 180
pF1KE2 IHEDNSTRSSQHFYYDGELFLSQNLETEEWTMPQSSRAQTLAMNVRNFLKEDAMKTKTHY
::::::::::::: :: :::::::::::
NP_001 --------------------------------PQSSRAQTLAMNVTNFWKEDAMKTKTHY
110 120 130
190 200 210 220 230 240
pF1KE2 HAMHADCLQELRRYLKSGVVLRRTVPPMVNVTRSEASEGNITVTCRASGFYPWNITLSWR
.::.:::::.:.:::::::..::::::::::: ::.::::::::::::.::: ::::.::
NP_001 RAMQADCLQKLQRYLKSGVAIRRTVPPMVNVTCSEVSEGNITVTCRASSFYPRNITLTWR
140 150 160 170 180 190
250 260 270 280 290 300
pF1KE2 QDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSGNHSTHPVPSGKV
::::::::.::::::::::::::::::::::: :::::::::::::::::.::::::::.
NP_001 QDGVSLSHNTQQWGDVLPDGNGTYQTWVATRIRQGEEQRFTCYMEHSGNHGTHPVPSGKA
200 210 220 230 240 250
310 320 330 340 350 360
pF1KE2 LVLQSHWQTFHVSAVAAAAIFVIIIFYVRCCKKKTSAAEGPELVSLQVLDQHPVGTSDHR
:::::. : ..: . .:::. : :::::::::::::::::::::::::::.:::
NP_001 LVLQSQRTDFPYVSAAMPCFVIIIILCVPCCKKKTSAAEGPELVSLQVLDQHPVGTGDHR
260 270 280 290 300 310
370 380
pF1KE2 DATQLGFQPLMSDLGSTGSTEGT
::.::::::::: :::::::::
NP_001 DAAQLGFQPLMSATGSTGSTEGT
320 330 340
>>NP_001276083 (OMIM: 600169) MHC class I polypeptide-re (194 aa)
initn: 1021 init1: 1021 opt: 1030 Z-score: 1186.4 bits: 227.3 E(85289): 2.4e-59
Smith-Waterman score: 1030; 81.4% identity (90.4% similar) in 188 aa overlap (143-330:6-191)
120 130 140 150 160 170
pF1KE2 LQEIRVCEIHEDNSTRSSQHFYYDGELFLSQNLETEEWTMPQSSRAQTLAMNVRNFLKED
:.:. :. ::.. .. . . :::::::
NP_001 MGQRDQGLDRER-KGPQDDPGSYQGPERRNFLKED
10 20 30
180 190 200 210 220 230
pF1KE2 AMKTKTHYHAMHADCLQELRRYLKSGVVLRRTVPPMVNVTRSEASEGNITVTCRASGFYP
:::::::::::::::::::::::.::::::::::::::::::::::::::::::::.:::
NP_001 AMKTKTHYHAMHADCLQELRRYLESGVVLRRTVPPMVNVTRSEASEGNITVTCRASSFYP
40 50 60 70 80 90
240 250 260 270 280 290
pF1KE2 WNITLSWRQDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSGNHST
:: :.:::::::::::::::::::::::::::::::::::.::::::::::::::::::
NP_001 RNIILTWRQDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICRGEEQRFTCYMEHSGNHST
100 110 120 130 140 150
300 310 320 330 340 350
pF1KE2 HPVPSGKVLVLQSHWQTFHVSAVAAAAIFVIIIFYVRCCKKKTSAAEGPELVSLQVLDQH
:::::::::::::::::::::::::. . . .: :
NP_001 HPVPSGKVLVLQSHWQTFHVSAVAAGCCY-FCYYYFLCPLL
160 170 180 190
360 370 380
pF1KE2 PVGTSDHRDATQLGFQPLMSDLGSTGSTEGT
>>NP_001229971 (OMIM: 142840,177900,609423) HLA class I (366 aa)
initn: 366 init1: 150 opt: 520 Z-score: 599.4 bits: 119.6 E(85289): 1.2e-26
Smith-Waterman score: 520; 30.2% identity (63.5% similar) in 351 aa overlap (6-340:9-342)
10 20 30 40 50
pF1KE2 MGLGPVFLLLAGIFPFAPPGAAAEPHSLRYNLTVLSWDGSVQSGFLTEVHLDGQPFL
..:::.: . .. : . ::.:: :..: : . :.. ..: :.
NP_001 MRVMAPRALLLLLSGGLALTETWACS--HSMRYFDTAVSRPGRGEPRFISVGYVDDTQFV
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 RCDRQKC--RAKPQGQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIK---DQKE-GLH
: : . :..:.. :.:. : . :::::.. ... :..: ... .:.: : :
NP_001 RFDSDAASPRGEPRAPWVEQE-GPEYWDRETQNYKRQAQADRVSLRNLRGYYNQSEDGSH
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE2 SLQEIRVCEIHEDNST-RSSQHFYYDGELFLSQNLETEEWTMPQSSRAQTLAMNVRNFLK
.::.. :.. :. :. .. :::. ... : . . :: :.: :. .. :
NP_001 TLQRMYGCDLGPDGRLLRGYDQSAYDGKDYIALNEDLRSWTA-----ADTAAQITQR--K
120 130 140 150 160 170
180 190 200 210 220
pF1KE2 EDAMKTKTHYHA-MHADCLQELRRYLKSGV-VLRRTVPPMVNVTRSEASEGNITVTCRAS
.: .. . .: ... :.. :::::..: .:.:. :: ..::. :. . :. : :
NP_001 LEAARAAEQLRAYLEGTCVEWLRRYLENGKETLQRAEPPKTHVTHHPLSDHEATLRCWAL
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE2 GFYPWNITLSWRQDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSG
:::: .:::.:..:: . ..::. .. : :.::.: :.:. . .:.:::.::.:.: :
NP_001 GFYPAEITLTWQRDGEDQTQDTELV-ETRPAGDGTFQKWAAVVVPSGQEQRYTCHMQHEG
240 250 260 270 280
290 300 310 320 330 340
pF1KE2 NH-----STHPV--PSGKVLVLQSHWQTFHVSAVAAAAIFVIIIFYVRCCKKKTSAAEGP
. : .: :. .. . . .. : :: .:.. ... :..:.:...:
NP_001 LQEPLTLSWEPSSQPTIPIMGIVAGLAVLVVLAVLGAVVTAMM------CRRKSSGGKGG
290 300 310 320 330 340
350 360 370 380
pF1KE2 ELVSLQVLDQHPVGTSDHRDATQLGFQPLMSDLGSTGSTEGT
NP_001 SCSQAACSNSAQGSDESLITCKA
350 360
>>XP_016866297 (OMIM: 143010) PREDICTED: HLA class I his (399 aa)
initn: 408 init1: 146 opt: 520 Z-score: 598.9 bits: 119.6 E(85289): 1.3e-26
Smith-Waterman score: 520; 30.8% identity (61.6% similar) in 344 aa overlap (11-340:54-379)
10 20 30 40
pF1KE2 MGLGPVFLLLAGIFPFAPPGAAAEPHSLRYNLTVLSWDGS
: . : .:::. :::.: : .: :
XP_016 SGWKRPLPGVERGRPGGGEGLGEPRREEGRADLSPSSPPGS----HSLKYFHTSVSRPGR
30 40 50 60 70
50 60 70 80 90
pF1KE2 VQSGFLTEVHLDGQPFLRCDRQKC--RAKPQGQWAEDVLGNKTWDRETRDLTGNGKDLRM
. :.. ..: :.: : . : :.. : :. :.. ::::::. ... .:.
XP_016 GEPRFISVGYVDDTQFVRFDNDAASPRMVPRAPWMEQE-GSEYWDRETRSARDTAQIFRV
80 90 100 110 120 130
100 110 120 130 140 150
pF1KE2 TLAHIK---DQKE-GLHSLQEIRVCEIHEDNS-TRSSQHFYYDGELFLSQNLETEEWTMP
.: .. .:.: : :.:: .. ::. :. :. ..: :::. .:. : . . ::
XP_016 NLRTLRGYYNQSEAGSHTLQWMHGCELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWT--
140 150 160 170 180 190
160 170 180 190 200 210
pF1KE2 QSSRAQTLAMNVRNFLKEDAMKTKTHYHAMHAD-CLQELRRYLKSGV-VLRRTVPPMVNV
: : .. . ..:: ... : .:. : :.. :..::..: .: . :: ..:
XP_016 ----AVDTAAQISEQKSNDASEAE-HQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHV
200 210 220 230 240 250
220 230 240 250 260 270
pF1KE2 TRSEASEGNITVTCRASGFYPWNITLSWRQDGVSLSHDTQQWGDVLPDGNGTYQTWVATR
:. :. . :. : : :::: .:::.:.::: . ..::. .. : :.::.: :.:.
XP_016 THHPISDHEATLRCWALGFYPAEITLTWQQDGEGHTQDTELV-ETRPAGDGTFQKWAAVV
260 270 280 290 300 310
280 290 300 310 320
pF1KE2 ICQGEEQRFTCYMEHSG-----NHSTHPVPSGKVLVLQSHWQTFHVSAVAAAAIFVIIIF
. .:::::.::...: : . .:. . . .. ...:...:. . .:.
XP_016 VPSGEEQRYTCHVQHEGLPEPVTLRWKPASQPTIPIVGIIAGLVLLGSVVSGAVVAAVIW
320 330 340 350 360 370
330 340 350 360 370 380
pF1KE2 YVRCCKKKTSAAEGPELVSLQVLDQHPVGTSDHRDATQLGFQPLMSDLGSTGSTEGT
.::.:...:
XP_016 -----RKKSSGGKGGSYSKAEWSDSAQGSESHSL
380 390
383 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 03:55:29 2016 done: Tue Nov 8 03:55:30 2016
Total Scan time: 5.550 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]