Result of FASTA (ccds) for
pFN21AE2539
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2539, 680 aa
1>>>pF1KE2539 680 - 680 aa - 680 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.7473+/-0.00159; mu= -12.4734+/- 0.090
mean_var=517.6440+/-117.392, 0's: 0 Z-trim(106.1): 446 B-trim: 0 in 0/52
Lambda= 0.056371
statistics sampled from 8361 (8814) to 8361 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.624), E-opt: 0.2 (0.271), width: 16
Scan time: 3.190
The best scores are: opt bits E(32554)
CCDS44488.1 FGFR2 gene_id:2263|Hs108|chr10 ( 680) 4573 388.2 2e-107
CCDS53584.1 FGFR2 gene_id:2263|Hs108|chr10 ( 707) 4385 373.0 8.4e-103
CCDS73210.1 FGFR2 gene_id:2263|Hs108|chr10 ( 732) 4385 373.0 8.6e-103
CCDS44489.1 FGFR2 gene_id:2263|Hs108|chr10 ( 769) 4342 369.5 1e-101
CCDS7620.2 FGFR2 gene_id:2263|Hs108|chr10 ( 822) 4337 369.1 1.4e-101
CCDS31298.1 FGFR2 gene_id:2263|Hs108|chr10 ( 821) 4154 354.2 4.2e-97
CCDS81515.1 FGFR2 gene_id:2263|Hs108|chr10 ( 819) 4130 352.3 1.6e-96
CCDS44485.1 FGFR2 gene_id:2263|Hs108|chr10 ( 704) 3953 337.8 3.2e-92
CCDS43731.1 FGFR1 gene_id:2260|Hs108|chr8 ( 731) 3399 292.8 1.2e-78
CCDS43730.1 FGFR1 gene_id:2260|Hs108|chr8 ( 733) 3396 292.5 1.4e-78
CCDS43732.1 FGFR1 gene_id:2260|Hs108|chr8 ( 820) 3355 289.3 1.5e-77
CCDS55223.1 FGFR1 gene_id:2260|Hs108|chr8 ( 853) 3355 289.3 1.6e-77
CCDS6107.2 FGFR1 gene_id:2260|Hs108|chr8 ( 822) 3352 289.0 1.8e-77
CCDS55221.1 FGFR1 gene_id:2260|Hs108|chr8 ( 812) 3328 287.1 6.9e-77
CCDS55222.1 FGFR1 gene_id:2260|Hs108|chr8 ( 820) 3328 287.1 7e-77
CCDS81514.1 FGFR2 gene_id:2263|Hs108|chr10 ( 593) 3290 283.8 4.8e-76
CCDS54706.1 FGFR3 gene_id:2261|Hs108|chr4 ( 808) 3081 267.0 7.7e-71
CCDS3353.1 FGFR3 gene_id:2261|Hs108|chr4 ( 806) 2966 257.6 5e-68
CCDS4410.1 FGFR4 gene_id:2264|Hs108|chr5 ( 802) 2816 245.4 2.4e-64
CCDS44486.1 FGFR2 gene_id:2263|Hs108|chr10 ( 709) 2765 241.2 3.8e-63
CCDS44487.1 FGFR2 gene_id:2263|Hs108|chr10 ( 705) 2306 203.9 6.6e-52
CCDS3354.1 FGFR3 gene_id:2261|Hs108|chr4 ( 694) 1952 175.1 3e-43
CCDS4411.1 FGFR4 gene_id:2264|Hs108|chr5 ( 762) 1680 153.0 1.5e-36
CCDS78096.1 FGFR4 gene_id:2264|Hs108|chr5 ( 734) 1534 141.1 5.4e-33
CCDS53525.1 RET gene_id:5979|Hs108|chr10 (1072) 1099 105.9 3.1e-22
CCDS7200.1 RET gene_id:5979|Hs108|chr10 (1114) 1099 105.9 3.2e-22
CCDS78389.1 TEK gene_id:7010|Hs108|chr9 ( 976) 832 84.2 1e-15
CCDS75825.1 TEK gene_id:7010|Hs108|chr9 (1081) 832 84.2 1.1e-15
CCDS6519.1 TEK gene_id:7010|Hs108|chr9 (1124) 832 84.2 1.1e-15
CCDS482.1 TIE1 gene_id:7075|Hs108|chr1 (1138) 827 83.8 1.5e-15
CCDS58399.1 NTRK3 gene_id:4916|Hs108|chr15 ( 817) 794 81.0 7.6e-15
CCDS10340.1 NTRK3 gene_id:4916|Hs108|chr15 ( 825) 791 80.7 9e-15
CCDS75874.1 MUSK gene_id:4593|Hs108|chr9 ( 783) 749 77.3 9.3e-14
CCDS48005.1 MUSK gene_id:4593|Hs108|chr9 ( 869) 749 77.4 1e-13
CCDS5116.1 ROS1 gene_id:6098|Hs108|chr6 (2347) 738 76.9 3.6e-13
CCDS35050.1 NTRK2 gene_id:4915|Hs108|chr9 ( 822) 725 75.4 3.7e-13
CCDS6671.1 NTRK2 gene_id:4915|Hs108|chr9 ( 838) 719 74.9 5.3e-13
CCDS3497.1 KDR gene_id:3791|Hs108|chr4 (1356) 716 74.9 8.6e-13
CCDS9330.1 FLT1 gene_id:2321|Hs108|chr13 (1338) 714 74.7 9.5e-13
CCDS30890.1 NTRK1 gene_id:4914|Hs108|chr1 ( 760) 703 73.5 1.2e-12
CCDS30891.1 NTRK1 gene_id:4914|Hs108|chr1 ( 790) 703 73.6 1.3e-12
CCDS1161.1 NTRK1 gene_id:4914|Hs108|chr1 ( 796) 698 73.2 1.7e-12
CCDS47058.1 KIT gene_id:3815|Hs108|chr4 ( 972) 689 72.5 3.2e-12
CCDS3496.1 KIT gene_id:3815|Hs108|chr4 ( 976) 689 72.5 3.2e-12
CCDS73785.1 IGF1R gene_id:3480|Hs108|chr15 (1366) 678 71.8 7.4e-12
CCDS10378.1 IGF1R gene_id:3480|Hs108|chr15 (1367) 678 71.8 7.4e-12
CCDS626.1 ROR1 gene_id:4919|Hs108|chr1 ( 937) 668 70.8 1e-11
CCDS6691.1 ROR2 gene_id:4920|Hs108|chr9 ( 943) 662 70.3 1.4e-11
CCDS42487.1 INSR gene_id:3643|Hs108|chr19 (1370) 666 70.8 1.5e-11
CCDS12176.1 INSR gene_id:3643|Hs108|chr19 (1382) 666 70.8 1.5e-11
>>CCDS44488.1 FGFR2 gene_id:2263|Hs108|chr10 (680 aa)
initn: 4573 init1: 4573 opt: 4573 Z-score: 2041.9 bits: 388.2 E(32554): 2e-107
Smith-Waterman score: 4573; 100.0% identity (100.0% similar) in 680 aa overlap (1-680:1-680)
10 20 30 40 50 60
pF1KE2 MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEDAISSGDDEDDTDGAEDFVSENSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEDAISSGDDEDDTDGAEDFVSENSN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 NKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 NKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 RNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 RNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 VGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSGINSSNAEVLALFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 VGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSGINSSNAEVLALFN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 VTEADAGEYICKVSNYIGQANQSAWLTVLPKQQAPGREKEITASPDYLEIAIYCIGVFLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 VTEADAGEYICKVSNYIGQANQSAWLTVLPKQQAPGREKEITASPDYLEIAIYCIGVFLI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 ACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 ACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRIT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 TRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 TRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 KEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 KEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYAS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 KGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 KGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 ARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 ARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 FGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 FGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRP
610 620 630 640 650 660
670 680
pF1KE2 TFKQLVEDLDRILTLTTNEI
::::::::::::::::::::
CCDS44 TFKQLVEDLDRILTLTTNEI
670 680
>>CCDS53584.1 FGFR2 gene_id:2263|Hs108|chr10 (707 aa)
initn: 4276 init1: 2711 opt: 4385 Z-score: 1959.1 bits: 373.0 E(32554): 8.4e-103
Smith-Waterman score: 4385; 96.0% identity (97.8% similar) in 681 aa overlap (1-679:1-678)
10 20 30 40 50 60
pF1KE2 MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEDAISSGDDEDDTDGAEDFVSENSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEDAISSGDDEDDTDGAEDFVSENSN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 NKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 NKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 RNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 RNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTV
130 140 150 160 170 180
190 200 210 220 230
pF1KE2 VGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSGINSSNAEVLALF-
:::::::::::::::::::::::::::::::::::::::::::: .:.:... :. .:.
CCDS53 VGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYI
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE2 -NVTEADAGEYICKVSNYIGQANQSAWLTVLPKQQAPGREKEITASPDYLEIAIYCIGVF
::: ::::: : ..: :: . .:::::::: :::::::::::::::::::::::::
CCDS53 RNVTFEDAGEYTCLAGNSIGISFHSAWLTVLP---APGREKEITASPDYLEIAIYCIGVF
250 260 270 280 290
300 310 320 330 340 350
pF1KE2 LIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 LIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVR
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE2 ITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 ITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKD
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE2 KPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 KPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEY
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE2 ASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 ASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRD
480 490 500 510 520 530
540 550 560 570 580 590
pF1KE2 LAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 LAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDV
540 550 560 570 580 590
600 610 620 630 640 650
pF1KE2 WSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 WSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQ
600 610 620 630 640 650
660 670 680
pF1KE2 RPTFKQLVEDLDRILTLTTNEI
:::::::::::::::::::::
CCDS53 RPTFKQLVEDLDRILTLTTNEEEKKVSGAVDCHKPPCNPSHLPCVLAVDQ
660 670 680 690 700
>>CCDS73210.1 FGFR2 gene_id:2263|Hs108|chr10 (732 aa)
initn: 4276 init1: 2711 opt: 4385 Z-score: 1958.9 bits: 373.0 E(32554): 8.6e-103
Smith-Waterman score: 4385; 96.0% identity (97.8% similar) in 681 aa overlap (1-679:1-678)
10 20 30 40 50 60
pF1KE2 MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEDAISSGDDEDDTDGAEDFVSENSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEDAISSGDDEDDTDGAEDFVSENSN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 NKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 NKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 RNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 RNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTV
130 140 150 160 170 180
190 200 210 220 230
pF1KE2 VGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSGINSSNAEVLALF-
:::::::::::::::::::::::::::::::::::::::::::: .:.:... :. .:.
CCDS73 VGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYI
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE2 -NVTEADAGEYICKVSNYIGQANQSAWLTVLPKQQAPGREKEITASPDYLEIAIYCIGVF
::: ::::: : ..: :: . .:::::::: :::::::::::::::::::::::::
CCDS73 RNVTFEDAGEYTCLAGNSIGISFHSAWLTVLP---APGREKEITASPDYLEIAIYCIGVF
250 260 270 280 290
300 310 320 330 340 350
pF1KE2 LIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 LIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVR
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE2 ITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 ITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKD
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE2 KPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 KPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEY
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE2 ASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 ASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRD
480 490 500 510 520 530
540 550 560 570 580 590
pF1KE2 LAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 LAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDV
540 550 560 570 580 590
600 610 620 630 640 650
pF1KE2 WSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 WSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQ
600 610 620 630 640 650
660 670 680
pF1KE2 RPTFKQLVEDLDRILTLTTNEI
:::::::::::::::::::::
CCDS73 RPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYE
660 670 680 690 700 710
>>CCDS44489.1 FGFR2 gene_id:2263|Hs108|chr10 (769 aa)
initn: 4342 init1: 4342 opt: 4342 Z-score: 1939.8 bits: 369.5 E(32554): 1e-101
Smith-Waterman score: 4342; 100.0% identity (100.0% similar) in 644 aa overlap (37-680:126-769)
10 20 30 40 50 60
pF1KE2 FICLVVVTMATLSLARPSFSLVEDTTLEPEDAISSGDDEDDTDGAEDFVSENSNNKRAPY
::::::::::::::::::::::::::::::
CCDS44 GATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPY
100 110 120 130 140 150
70 80 90 100 110 120
pF1KE2 WTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 WTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWS
160 170 180 190 200 210
130 140 150 160 170 180
pF1KE2 LIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 LIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVE
220 230 240 250 260 270
190 200 210 220 230 240
pF1KE2 FVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSGINSSNAEVLALFNVTEADA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 FVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSGINSSNAEVLALFNVTEADA
280 290 300 310 320 330
250 260 270 280 290 300
pF1KE2 GEYICKVSNYIGQANQSAWLTVLPKQQAPGREKEITASPDYLEIAIYCIGVFLIACMVVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 GEYICKVSNYIGQANQSAWLTVLPKQQAPGREKEITASPDYLEIAIYCIGVFLIACMVVT
340 350 360 370 380 390
310 320 330 340 350 360
pF1KE2 VILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 VILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSST
400 410 420 430 440 450
370 380 390 400 410 420
pF1KE2 ADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 ADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTV
460 470 480 490 500 510
430 440 450 460 470 480
pF1KE2 AVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 AVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLRE
520 530 540 550 560 570
490 500 510 520 530 540
pF1KE2 YLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 YLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLV
580 590 600 610 620 630
550 560 570 580 590 600
pF1KE2 TENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 TENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMW
640 650 660 670 680 690
610 620 630 640 650 660
pF1KE2 EIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 EIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLV
700 710 720 730 740 750
670 680
pF1KE2 EDLDRILTLTTNEI
::::::::::::::
CCDS44 EDLDRILTLTTNEI
760
>>CCDS7620.2 FGFR2 gene_id:2263|Hs108|chr10 (822 aa)
initn: 4337 init1: 4337 opt: 4337 Z-score: 1937.2 bits: 369.1 E(32554): 1.4e-101
Smith-Waterman score: 4337; 100.0% identity (100.0% similar) in 643 aa overlap (37-679:126-768)
10 20 30 40 50 60
pF1KE2 FICLVVVTMATLSLARPSFSLVEDTTLEPEDAISSGDDEDDTDGAEDFVSENSNNKRAPY
::::::::::::::::::::::::::::::
CCDS76 GATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPY
100 110 120 130 140 150
70 80 90 100 110 120
pF1KE2 WTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 WTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWS
160 170 180 190 200 210
130 140 150 160 170 180
pF1KE2 LIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 LIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVE
220 230 240 250 260 270
190 200 210 220 230 240
pF1KE2 FVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSGINSSNAEVLALFNVTEADA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 FVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSGINSSNAEVLALFNVTEADA
280 290 300 310 320 330
250 260 270 280 290 300
pF1KE2 GEYICKVSNYIGQANQSAWLTVLPKQQAPGREKEITASPDYLEIAIYCIGVFLIACMVVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 GEYICKVSNYIGQANQSAWLTVLPKQQAPGREKEITASPDYLEIAIYCIGVFLIACMVVT
340 350 360 370 380 390
310 320 330 340 350 360
pF1KE2 VILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 VILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSST
400 410 420 430 440 450
370 380 390 400 410 420
pF1KE2 ADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 ADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTV
460 470 480 490 500 510
430 440 450 460 470 480
pF1KE2 AVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 AVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLRE
520 530 540 550 560 570
490 500 510 520 530 540
pF1KE2 YLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 YLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLV
580 590 600 610 620 630
550 560 570 580 590 600
pF1KE2 TENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 TENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMW
640 650 660 670 680 690
610 620 630 640 650 660
pF1KE2 EIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 EIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLV
700 710 720 730 740 750
670 680
pF1KE2 EDLDRILTLTTNEI
:::::::::::::
CCDS76 EDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPH
760 770 780 790 800 810
>>CCDS31298.1 FGFR2 gene_id:2263|Hs108|chr10 (821 aa)
initn: 4045 init1: 2711 opt: 4154 Z-score: 1856.8 bits: 354.2 E(32554): 4.2e-97
Smith-Waterman score: 4154; 95.8% identity (97.7% similar) in 645 aa overlap (37-679:126-767)
10 20 30 40 50 60
pF1KE2 FICLVVVTMATLSLARPSFSLVEDTTLEPEDAISSGDDEDDTDGAEDFVSENSNNKRAPY
::::::::::::::::::::::::::::::
CCDS31 GATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPY
100 110 120 130 140 150
70 80 90 100 110 120
pF1KE2 WTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 WTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWS
160 170 180 190 200 210
130 140 150 160 170 180
pF1KE2 LIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 LIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVE
220 230 240 250 260 270
190 200 210 220 230 240
pF1KE2 FVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSGINSSNAEVLALF--NVTEA
:::::::::::::::::::::::::::::::::::::: .:.:... :. .:. :::
CCDS31 FVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFE
280 290 300 310 320 330
250 260 270 280 290 300
pF1KE2 DAGEYICKVSNYIGQANQSAWLTVLPKQQAPGREKEITASPDYLEIAIYCIGVFLIACMV
::::: : ..: :: . .:::::::: :::::::::::::::::::::::::::::::
CCDS31 DAGEYTCLAGNSIGISFHSAWLTVLP---APGREKEITASPDYLEIAIYCIGVFLIACMV
340 350 360 370 380 390
310 320 330 340 350 360
pF1KE2 VTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 VTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLS
400 410 420 430 440 450
370 380 390 400 410 420
pF1KE2 STADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 STADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAV
460 470 480 490 500 510
430 440 450 460 470 480
pF1KE2 TVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 TVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNL
520 530 540 550 560 570
490 500 510 520 530 540
pF1KE2 REYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 REYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNV
580 590 600 610 620 630
550 560 570 580 590 600
pF1KE2 LVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 LVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVL
640 650 660 670 680 690
610 620 630 640 650 660
pF1KE2 MWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 MWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQ
700 710 720 730 740 750
670 680
pF1KE2 LVEDLDRILTLTTNEI
:::::::::::::::
CCDS31 LVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQY
760 770 780 790 800 810
>>CCDS81515.1 FGFR2 gene_id:2263|Hs108|chr10 (819 aa)
initn: 3598 init1: 2264 opt: 4130 Z-score: 1846.3 bits: 352.3 E(32554): 1.6e-96
Smith-Waterman score: 4130; 95.5% identity (97.4% similar) in 645 aa overlap (37-679:126-765)
10 20 30 40 50 60
pF1KE2 FICLVVVTMATLSLARPSFSLVEDTTLEPEDAISSGDDEDDTDGAEDFVSENSNNKRAPY
::::::::::::::::::::::::::::::
CCDS81 GATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPY
100 110 120 130 140 150
70 80 90 100 110 120
pF1KE2 WTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 WTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWS
160 170 180 190 200 210
130 140 150 160 170 180
pF1KE2 LIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 LIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVE
220 230 240 250 260 270
190 200 210 220 230 240
pF1KE2 FVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSGINSSNAEVLALF--NVTEA
:::::::::::::::::::::::::::::::::::::: .:.:... :. .:. :::
CCDS81 FVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFE
280 290 300 310 320 330
250 260 270 280 290 300
pF1KE2 DAGEYICKVSNYIGQANQSAWLTVLPKQQAPGREKEITASPDYLEIAIYCIGVFLIACMV
::::: : ..: :: . .:::::::: :::::::::::::::::::::::::::::::
CCDS81 DAGEYTCLAGNSIGISFHSAWLTVLP---APGREKEITASPDYLEIAIYCIGVFLIACMV
340 350 360 370 380 390
310 320 330 340 350 360
pF1KE2 VTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLS
::::::::::::::::::::::::::::::::::: :::::::::::::::::::::::
CCDS81 VTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQ--VSAESSSSMNSNTPLVRITTRLS
400 410 420 430 440 450
370 380 390 400 410 420
pF1KE2 STADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 STADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAV
460 470 480 490 500 510
430 440 450 460 470 480
pF1KE2 TVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 TVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNL
520 530 540 550 560 570
490 500 510 520 530 540
pF1KE2 REYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 REYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNV
580 590 600 610 620 630
550 560 570 580 590 600
pF1KE2 LVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 LVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVL
640 650 660 670 680 690
610 620 630 640 650 660
pF1KE2 MWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 MWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQ
700 710 720 730 740 750
670 680
pF1KE2 LVEDLDRILTLTTNEI
:::::::::::::::
CCDS81 LVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQY
760 770 780 790 800 810
>>CCDS44485.1 FGFR2 gene_id:2263|Hs108|chr10 (704 aa)
initn: 3421 init1: 2264 opt: 3953 Z-score: 1769.3 bits: 337.8 E(32554): 3.2e-92
Smith-Waterman score: 4121; 91.8% identity (93.5% similar) in 681 aa overlap (1-679:1-650)
10 20 30 40 50 60
pF1KE2 MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEDAISSGDDEDDTDGAEDFVSENSN
:::::::::::::::::::::::::::::::::::: :
CCDS44 MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEGA----------------------
10 20 30
70 80 90 100 110 120
pF1KE2 NKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 ----PYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKV
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE2 RNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 RNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTV
100 110 120 130 140 150
190 200 210 220 230
pF1KE2 VGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSGINSSNAEVLALF-
:::::::::::::::::::::::::::::::::::::::::::: .:.:... :. .:.
CCDS44 VGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYI
160 170 180 190 200 210
240 250 260 270 280 290
pF1KE2 -NVTEADAGEYICKVSNYIGQANQSAWLTVLPKQQAPGREKEITASPDYLEIAIYCIGVF
::: ::::: : ..: :: . .:::::::: :::::::::::::::::::::::::
CCDS44 RNVTFEDAGEYTCLAGNSIGISFHSAWLTVLP---APGREKEITASPDYLEIAIYCIGVF
220 230 240 250 260 270
300 310 320 330 340 350
pF1KE2 LIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVR
::::::::::::::::::::::::::::::::::::::::: :::::::::::::::::
CCDS44 LIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQ--VSAESSSSMNSNTPLVR
280 290 300 310 320
360 370 380 390 400 410
pF1KE2 ITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 ITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKD
330 340 350 360 370 380
420 430 440 450 460 470
pF1KE2 KPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 KPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEY
390 400 410 420 430 440
480 490 500 510 520 530
pF1KE2 ASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 ASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRD
450 460 470 480 490 500
540 550 560 570 580 590
pF1KE2 LAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 LAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDV
510 520 530 540 550 560
600 610 620 630 640 650
pF1KE2 WSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 WSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQ
570 580 590 600 610 620
660 670 680
pF1KE2 RPTFKQLVEDLDRILTLTTNEI
:::::::::::::::::::::
CCDS44 RPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYE
630 640 650 660 670 680
>>CCDS43731.1 FGFR1 gene_id:2260|Hs108|chr8 (731 aa)
initn: 3266 init1: 1937 opt: 3399 Z-score: 1525.6 bits: 292.8 E(32554): 1.2e-78
Smith-Waterman score: 3399; 73.4% identity (88.9% similar) in 684 aa overlap (1-679:1-673)
10 20 30 40 50 60
pF1KE2 MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEDAISSGDDEDDTDGAEDFVSENSN
: :: .. .:.. ::: :::: :: .::. :..:.:: : . . .:..:
CCDS43 MWSWKCLLFWAVLVTATLCTARPS------PTLPEQDALPSSEDDDDDDDSSSEEKETDN
10 20 30 40 50
70 80 90 100 110
pF1KE2 NKR---APYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGG
.: :::::. :::::.:::::::.::::.::..:.: ::.:::::::::: .:::::
CCDS43 TKPNPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGG
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE2 YKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANA
:::: ::.::.::::::::::::.::::::::::::.::::::::::::::::::::
CCDS43 YKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANK
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE2 STVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSGINSSNAE--V
....:..:::.:::::: ::::::.::.: :::: :::.:::...:: .:.:... : :
CCDS43 TVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEV
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE2 LALFNVTEADAGEYICKVSNYIGQANQSAWLTVLPKQQAPGREKEITASPDYLEIAIYCI
: : ::. ::::: : ..: :: ...::::::: .: .. . .:: :::: :::
CCDS43 LHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVL---EALEERPAVMTSPLYLEIIIYCT
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE2 GVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTP
:.:::.::: .::. .::. ::: :: :: :::::.: :::::::::::.::.::::..
CCDS43 GAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVL
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE2 LVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGI
::: .::::.. ::::::::::::::::.::.:::.:.::::::::::::::.:::.:.
CCDS43 LVR-PSRLSSSG-TPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGL
360 370 380 390 400
420 430 440 450 460 470
pF1KE2 DKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVI
:::::.... :::::::.::::::::::.:::::::::::::::::::::::::::::::
CCDS43 DKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVI
410 420 430 440 450 460
480 490 500 510 520 530
pF1KE2 VEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCI
:::::::::::::.::::::.:: :. .. ::::.. ::::::.::.:::::::::.:::
CCDS43 VEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCI
470 480 490 500 510 520
540 550 560 570 580 590
pF1KE2 HRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQ
:::::::::::::.::::::::::::::..:::::::::::::::::::::::::.::::
CCDS43 HRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQ
530 540 550 560 570 580
600 610 620 630 640 650
pF1KE2 SDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAV
:::::::::.:::::::::::::.::::::::::::::::::.:::::::::::::::::
CCDS43 SDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAV
590 600 610 620 630 640
660 670 680
pF1KE2 PSQRPTFKQLVEDLDRILTLTTNEI
:::::::::::::::::..::.:.
CCDS43 PSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEP
650 660 670 680 690 700
>>CCDS43730.1 FGFR1 gene_id:2260|Hs108|chr8 (733 aa)
initn: 3238 init1: 1937 opt: 3396 Z-score: 1524.2 bits: 292.5 E(32554): 1.4e-78
Smith-Waterman score: 3396; 73.2% identity (88.9% similar) in 686 aa overlap (1-679:1-675)
10 20 30 40 50
pF1KE2 MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEDAISSGDDEDDTD--GAEDFVSEN
: :: .. .:.. ::: :::: :: .::. :..:.:: : ..:. ..:
CCDS43 MWSWKCLLFWAVLVTATLCTARPS------PTLPEQDALPSSEDDDDDDDSSSEEKETDN
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 SNNKR---APYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRI
.. .: :::::. :::::.:::::::.::::.::..:.: ::.:::::::::: .:::
CCDS43 TKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRI
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE2 GGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPA
:::::: ::.::.::::::::::::.::::::::::::.:::::::::::::::::::
CCDS43 GGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPA
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE2 NASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSGINSSNAE-
: ....:..:::.:::::: ::::::.::.: :::: :::.:::...:: .:.:... :
CCDS43 NKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEM
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE2 -VLALFNVTEADAGEYICKVSNYIGQANQSAWLTVLPKQQAPGREKEITASPDYLEIAIY
:: : ::. ::::: : ..: :: ...::::::: .: .. . .:: :::: ::
CCDS43 EVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVL---EALEERPAVMTSPLYLEIIIY
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE2 CIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSN
: :.:::.::: .::. .::. ::: :: :: :::::.: :::::::::::.::.::::.
CCDS43 CTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSG
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE2 TPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAV
. ::: .::::.. ::::::::::::::::.::.:::.:.::::::::::::::.:::.
CCDS43 VLLVR-PSRLSSSG-TPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAI
360 370 380 390 400
420 430 440 450 460 470
pF1KE2 GIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLY
:.:::::.... :::::::.::::::::::.:::::::::::::::::::::::::::::
CCDS43 GLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLY
410 420 430 440 450 460
480 490 500 510 520 530
pF1KE2 VIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQK
:::::::::::::::.::::::.:: :. .. ::::.. ::::::.::.:::::::::.:
CCDS43 VIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKK
470 480 490 500 510 520
540 550 560 570 580 590
pF1KE2 CIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYT
:::::::::::::::.::::::::::::::..:::::::::::::::::::::::::.::
CCDS43 CIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYT
530 540 550 560 570 580
600 610 620 630 640 650
pF1KE2 HQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWH
:::::::::::.:::::::::::::.::::::::::::::::::.:::::::::::::::
CCDS43 HQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWH
590 600 610 620 630 640
660 670 680
pF1KE2 AVPSQRPTFKQLVEDLDRILTLTTNEI
:::::::::::::::::::..::.:.
CCDS43 AVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSH
650 660 670 680 690 700
680 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 03:45:17 2016 done: Tue Nov 8 03:45:18 2016
Total Scan time: 3.190 Total Display time: 0.180
Function used was FASTA [36.3.4 Apr, 2011]