Result of FASTA (omim) for
pFN21AE2537
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2537, 285 aa
1>>>pF1KE2537 285 - 285 aa - 285 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2335+/-0.000377; mu= 16.0201+/- 0.023
mean_var=67.8316+/-13.546, 0's: 0 Z-trim(113.0): 19 B-trim: 90 in 1/49
Lambda= 0.155725
statistics sampled from 22162 (22173) to 22162 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.639), E-opt: 0.2 (0.26), width: 16
Scan time: 7.360
The best scores are: opt bits E(85289)
NP_036269 (OMIM: 604743) N(G),N(G)-dimethylarginin ( 285) 1853 425.1 7.2e-119
XP_016856378 (OMIM: 604743) PREDICTED: N(G),N(G)-d ( 192) 1197 277.7 1.2e-74
XP_011539460 (OMIM: 604743) PREDICTED: N(G),N(G)-d ( 185) 1195 277.2 1.6e-74
NP_001317584 (OMIM: 604743) N(G),N(G)-dimethylargi ( 185) 1195 277.2 1.6e-74
XP_005270764 (OMIM: 604743) PREDICTED: N(G),N(G)-d ( 190) 1195 277.2 1.6e-74
XP_005270767 (OMIM: 604743) PREDICTED: N(G),N(G)-d ( 182) 1182 274.3 1.2e-73
NP_001127917 (OMIM: 604743) N(G),N(G)-dimethylargi ( 182) 1182 274.3 1.2e-73
NP_039268 (OMIM: 604744) N(G),N(G)-dimethylarginin ( 285) 899 210.8 2.4e-54
XP_011512750 (OMIM: 604744) PREDICTED: N(G),N(G)-d ( 285) 899 210.8 2.4e-54
NP_001289936 (OMIM: 604744) N(G),N(G)-dimethylargi ( 285) 899 210.8 2.4e-54
NP_001289937 (OMIM: 604744) N(G),N(G)-dimethylargi ( 285) 899 210.8 2.4e-54
>>NP_036269 (OMIM: 604743) N(G),N(G)-dimethylarginine di (285 aa)
initn: 1853 init1: 1853 opt: 1853 Z-score: 2255.0 bits: 425.1 E(85289): 7.2e-119
Smith-Waterman score: 1853; 100.0% identity (100.0% similar) in 285 aa overlap (1-285:1-285)
10 20 30 40 50 60
pF1KE2 MAGLGHPAAFGRATHAVVRALPESLGQHALRSAKGEEVDVARAERQHQLYVGVLGSKLGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MAGLGHPAAFGRATHAVVRALPESLGQHALRSAKGEEVDVARAERQHQLYVGVLGSKLGL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 QVVELPADESLPDCVFVEDVAVVCEETALITRPGAPSRRKEVDMMKEALEKLQLNIVEMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 QVVELPADESLPDCVFVEDVAVVCEETALITRPGAPSRRKEVDMMKEALEKLQLNIVEMK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 DENATLDGGDVLFTGREFFVGLSKRTNQRGAEILADTFKDYAVSTVPVADGLHLKSFCSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 DENATLDGGDVLFTGREFFVGLSKRTNQRGAEILADTFKDYAVSTVPVADGLHLKSFCSM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 AGPNLIAIGSSESAQKALKIMQQMSDHRYDKLTVPDDIAANCIYLNIPNKGHVLLHRTPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 AGPNLIAIGSSESAQKALKIMQQMSDHRYDKLTVPDDIAANCIYLNIPNKGHVLLHRTPE
190 200 210 220 230 240
250 260 270 280
pF1KE2 EYPESAKVYEKLKDHMLIPVSMSELEKVDGLLTCCSVLINKKVDS
:::::::::::::::::::::::::::::::::::::::::::::
NP_036 EYPESAKVYEKLKDHMLIPVSMSELEKVDGLLTCCSVLINKKVDS
250 260 270 280
>>XP_016856378 (OMIM: 604743) PREDICTED: N(G),N(G)-dimet (192 aa)
initn: 1197 init1: 1197 opt: 1197 Z-score: 1461.0 bits: 277.7 E(85289): 1.2e-74
Smith-Waterman score: 1197; 99.5% identity (100.0% similar) in 185 aa overlap (101-285:8-192)
80 90 100 110 120 130
pF1KE2 LPDCVFVEDVAVVCEETALITRPGAPSRRKEVDMMKEALEKLQLNIVEMKDENATLDGGD
.:::::::::::::::::::::::::::::
XP_016 MWLYGLGQVDMMKEALEKLQLNIVEMKDENATLDGGD
10 20 30
140 150 160 170 180 190
pF1KE2 VLFTGREFFVGLSKRTNQRGAEILADTFKDYAVSTVPVADGLHLKSFCSMAGPNLIAIGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLFTGREFFVGLSKRTNQRGAEILADTFKDYAVSTVPVADGLHLKSFCSMAGPNLIAIGS
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE2 SESAQKALKIMQQMSDHRYDKLTVPDDIAANCIYLNIPNKGHVLLHRTPEEYPESAKVYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SESAQKALKIMQQMSDHRYDKLTVPDDIAANCIYLNIPNKGHVLLHRTPEEYPESAKVYE
100 110 120 130 140 150
260 270 280
pF1KE2 KLKDHMLIPVSMSELEKVDGLLTCCSVLINKKVDS
:::::::::::::::::::::::::::::::::::
XP_016 KLKDHMLIPVSMSELEKVDGLLTCCSVLINKKVDS
160 170 180 190
>>XP_011539460 (OMIM: 604743) PREDICTED: N(G),N(G)-dimet (185 aa)
initn: 1195 init1: 1195 opt: 1195 Z-score: 1458.8 bits: 277.2 E(85289): 1.6e-74
Smith-Waterman score: 1195; 100.0% identity (100.0% similar) in 184 aa overlap (102-285:2-185)
80 90 100 110 120 130
pF1KE2 PDCVFVEDVAVVCEETALITRPGAPSRRKEVDMMKEALEKLQLNIVEMKDENATLDGGDV
::::::::::::::::::::::::::::::
XP_011 MVDMMKEALEKLQLNIVEMKDENATLDGGDV
10 20 30
140 150 160 170 180 190
pF1KE2 LFTGREFFVGLSKRTNQRGAEILADTFKDYAVSTVPVADGLHLKSFCSMAGPNLIAIGSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFTGREFFVGLSKRTNQRGAEILADTFKDYAVSTVPVADGLHLKSFCSMAGPNLIAIGSS
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE2 ESAQKALKIMQQMSDHRYDKLTVPDDIAANCIYLNIPNKGHVLLHRTPEEYPESAKVYEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESAQKALKIMQQMSDHRYDKLTVPDDIAANCIYLNIPNKGHVLLHRTPEEYPESAKVYEK
100 110 120 130 140 150
260 270 280
pF1KE2 LKDHMLIPVSMSELEKVDGLLTCCSVLINKKVDS
::::::::::::::::::::::::::::::::::
XP_011 LKDHMLIPVSMSELEKVDGLLTCCSVLINKKVDS
160 170 180
>>NP_001317584 (OMIM: 604743) N(G),N(G)-dimethylarginine (185 aa)
initn: 1195 init1: 1195 opt: 1195 Z-score: 1458.8 bits: 277.2 E(85289): 1.6e-74
Smith-Waterman score: 1195; 100.0% identity (100.0% similar) in 184 aa overlap (102-285:2-185)
80 90 100 110 120 130
pF1KE2 PDCVFVEDVAVVCEETALITRPGAPSRRKEVDMMKEALEKLQLNIVEMKDENATLDGGDV
::::::::::::::::::::::::::::::
NP_001 MVDMMKEALEKLQLNIVEMKDENATLDGGDV
10 20 30
140 150 160 170 180 190
pF1KE2 LFTGREFFVGLSKRTNQRGAEILADTFKDYAVSTVPVADGLHLKSFCSMAGPNLIAIGSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFTGREFFVGLSKRTNQRGAEILADTFKDYAVSTVPVADGLHLKSFCSMAGPNLIAIGSS
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE2 ESAQKALKIMQQMSDHRYDKLTVPDDIAANCIYLNIPNKGHVLLHRTPEEYPESAKVYEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESAQKALKIMQQMSDHRYDKLTVPDDIAANCIYLNIPNKGHVLLHRTPEEYPESAKVYEK
100 110 120 130 140 150
260 270 280
pF1KE2 LKDHMLIPVSMSELEKVDGLLTCCSVLINKKVDS
::::::::::::::::::::::::::::::::::
NP_001 LKDHMLIPVSMSELEKVDGLLTCCSVLINKKVDS
160 170 180
>>XP_005270764 (OMIM: 604743) PREDICTED: N(G),N(G)-dimet (190 aa)
initn: 1195 init1: 1195 opt: 1195 Z-score: 1458.7 bits: 277.2 E(85289): 1.6e-74
Smith-Waterman score: 1195; 100.0% identity (100.0% similar) in 184 aa overlap (102-285:7-190)
80 90 100 110 120 130
pF1KE2 PDCVFVEDVAVVCEETALITRPGAPSRRKEVDMMKEALEKLQLNIVEMKDENATLDGGDV
::::::::::::::::::::::::::::::
XP_005 MCKCLWVDMMKEALEKLQLNIVEMKDENATLDGGDV
10 20 30
140 150 160 170 180 190
pF1KE2 LFTGREFFVGLSKRTNQRGAEILADTFKDYAVSTVPVADGLHLKSFCSMAGPNLIAIGSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LFTGREFFVGLSKRTNQRGAEILADTFKDYAVSTVPVADGLHLKSFCSMAGPNLIAIGSS
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE2 ESAQKALKIMQQMSDHRYDKLTVPDDIAANCIYLNIPNKGHVLLHRTPEEYPESAKVYEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESAQKALKIMQQMSDHRYDKLTVPDDIAANCIYLNIPNKGHVLLHRTPEEYPESAKVYEK
100 110 120 130 140 150
260 270 280
pF1KE2 LKDHMLIPVSMSELEKVDGLLTCCSVLINKKVDS
::::::::::::::::::::::::::::::::::
XP_005 LKDHMLIPVSMSELEKVDGLLTCCSVLINKKVDS
160 170 180 190
>>XP_005270767 (OMIM: 604743) PREDICTED: N(G),N(G)-dimet (182 aa)
initn: 1182 init1: 1182 opt: 1182 Z-score: 1443.1 bits: 274.3 E(85289): 1.2e-73
Smith-Waterman score: 1182; 100.0% identity (100.0% similar) in 182 aa overlap (104-285:1-182)
80 90 100 110 120 130
pF1KE2 CVFVEDVAVVCEETALITRPGAPSRRKEVDMMKEALEKLQLNIVEMKDENATLDGGDVLF
::::::::::::::::::::::::::::::
XP_005 MMKEALEKLQLNIVEMKDENATLDGGDVLF
10 20 30
140 150 160 170 180 190
pF1KE2 TGREFFVGLSKRTNQRGAEILADTFKDYAVSTVPVADGLHLKSFCSMAGPNLIAIGSSES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TGREFFVGLSKRTNQRGAEILADTFKDYAVSTVPVADGLHLKSFCSMAGPNLIAIGSSES
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE2 AQKALKIMQQMSDHRYDKLTVPDDIAANCIYLNIPNKGHVLLHRTPEEYPESAKVYEKLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AQKALKIMQQMSDHRYDKLTVPDDIAANCIYLNIPNKGHVLLHRTPEEYPESAKVYEKLK
100 110 120 130 140 150
260 270 280
pF1KE2 DHMLIPVSMSELEKVDGLLTCCSVLINKKVDS
::::::::::::::::::::::::::::::::
XP_005 DHMLIPVSMSELEKVDGLLTCCSVLINKKVDS
160 170 180
>>NP_001127917 (OMIM: 604743) N(G),N(G)-dimethylarginine (182 aa)
initn: 1182 init1: 1182 opt: 1182 Z-score: 1443.1 bits: 274.3 E(85289): 1.2e-73
Smith-Waterman score: 1182; 100.0% identity (100.0% similar) in 182 aa overlap (104-285:1-182)
80 90 100 110 120 130
pF1KE2 CVFVEDVAVVCEETALITRPGAPSRRKEVDMMKEALEKLQLNIVEMKDENATLDGGDVLF
::::::::::::::::::::::::::::::
NP_001 MMKEALEKLQLNIVEMKDENATLDGGDVLF
10 20 30
140 150 160 170 180 190
pF1KE2 TGREFFVGLSKRTNQRGAEILADTFKDYAVSTVPVADGLHLKSFCSMAGPNLIAIGSSES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGREFFVGLSKRTNQRGAEILADTFKDYAVSTVPVADGLHLKSFCSMAGPNLIAIGSSES
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE2 AQKALKIMQQMSDHRYDKLTVPDDIAANCIYLNIPNKGHVLLHRTPEEYPESAKVYEKLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQKALKIMQQMSDHRYDKLTVPDDIAANCIYLNIPNKGHVLLHRTPEEYPESAKVYEKLK
100 110 120 130 140 150
260 270 280
pF1KE2 DHMLIPVSMSELEKVDGLLTCCSVLINKKVDS
::::::::::::::::::::::::::::::::
NP_001 DHMLIPVSMSELEKVDGLLTCCSVLINKKVDS
160 170 180
>>NP_039268 (OMIM: 604744) N(G),N(G)-dimethylarginine di (285 aa)
initn: 915 init1: 778 opt: 899 Z-score: 1096.7 bits: 210.8 E(85289): 2.4e-54
Smith-Waterman score: 899; 52.0% identity (77.1% similar) in 279 aa overlap (4-278:1-279)
10 20 30 40 50
pF1KE2 MAGLGHPA-AFGRATHAVVRALPESLGQHALRSAKGEEVDVARAERQHQLYVGVLGSKLG
.: :. ..:: .::..:..::::.. .: .:.:.:.:.: . : : ..::
NP_039 MGTPGEGLGRCSHALIRGVPESLASGEGAGAGLPALDLAKAQREHGVLGGKLRQRLG
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 LQVVELPADESLPDCVFVEDVAVVCEETALITRPGAPSRRKEVDMMKEALEKLQLNIVEM
::..::: .:::: .. :.::. .::::::: .:.:: ::: ...::. : : :::.
NP_039 LQLLELPPEESLPLGPLLGDTAVIQGDTALITRPWSPARRPEVDGVRKALQDLGLRIVEI
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE2 KDENATLDGGDVLFTGREFFVGLSKRTNQRGAEILADTFKDYAVSTVPVADGLHLKSFCS
:::::::: ::::::::::::::: ::.:::::.::::.:.:::::::. ::...:.
NP_039 GDENATLDGTDVLFTGREFFVGLSKWTNHRGAEIVADTFRDFAVSTVPVSGPSHLRGLCG
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE2 MAGPNLIAIGSSESAQKALKIMQQMSDHRYDKLTVPDDIAANCIYL--NIPNKGHVLLHR
:.:: .. :::..::::.. : ..:: : .::.::: ::.:..: ..:. ::::
NP_039 MGGPRTVVAGSSDAAQKAVRAMAVLTDHPYASLTLPDDAAADCLFLRPGLPGVPPFLLHR
180 190 200 210 220 230
240 250 260 270 280
pF1KE2 TPEEYPESAKVYEKLKDHMLIPVSMSELEKVD-GLLTCCSVLINKKVDS
. :.: .. .::.: :.::: :::::. :: . : ::
NP_039 GGGDLPNSQEALQKLSDVTLVPVSCSELEKAGAGLSSLCLVLSTRPHS
240 250 260 270 280
>>XP_011512750 (OMIM: 604744) PREDICTED: N(G),N(G)-dimet (285 aa)
initn: 915 init1: 778 opt: 899 Z-score: 1096.7 bits: 210.8 E(85289): 2.4e-54
Smith-Waterman score: 899; 52.0% identity (77.1% similar) in 279 aa overlap (4-278:1-279)
10 20 30 40 50
pF1KE2 MAGLGHPA-AFGRATHAVVRALPESLGQHALRSAKGEEVDVARAERQHQLYVGVLGSKLG
.: :. ..:: .::..:..::::.. .: .:.:.:.:.: . : : ..::
XP_011 MGTPGEGLGRCSHALIRGVPESLASGEGAGAGLPALDLAKAQREHGVLGGKLRQRLG
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 LQVVELPADESLPDCVFVEDVAVVCEETALITRPGAPSRRKEVDMMKEALEKLQLNIVEM
::..::: .:::: .. :.::. .::::::: .:.:: ::: ...::. : : :::.
XP_011 LQLLELPPEESLPLGPLLGDTAVIQGDTALITRPWSPARRPEVDGVRKALQDLGLRIVEI
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE2 KDENATLDGGDVLFTGREFFVGLSKRTNQRGAEILADTFKDYAVSTVPVADGLHLKSFCS
:::::::: ::::::::::::::: ::.:::::.::::.:.:::::::. ::...:.
XP_011 GDENATLDGTDVLFTGREFFVGLSKWTNHRGAEIVADTFRDFAVSTVPVSGPSHLRGLCG
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE2 MAGPNLIAIGSSESAQKALKIMQQMSDHRYDKLTVPDDIAANCIYL--NIPNKGHVLLHR
:.:: .. :::..::::.. : ..:: : .::.::: ::.:..: ..:. ::::
XP_011 MGGPRTVVAGSSDAAQKAVRAMAVLTDHPYASLTLPDDAAADCLFLRPGLPGVPPFLLHR
180 190 200 210 220 230
240 250 260 270 280
pF1KE2 TPEEYPESAKVYEKLKDHMLIPVSMSELEKVD-GLLTCCSVLINKKVDS
. :.: .. .::.: :.::: :::::. :: . : ::
XP_011 GGGDLPNSQEALQKLSDVTLVPVSCSELEKAGAGLSSLCLVLSTRPHS
240 250 260 270 280
>>NP_001289936 (OMIM: 604744) N(G),N(G)-dimethylarginine (285 aa)
initn: 915 init1: 778 opt: 899 Z-score: 1096.7 bits: 210.8 E(85289): 2.4e-54
Smith-Waterman score: 899; 52.0% identity (77.1% similar) in 279 aa overlap (4-278:1-279)
10 20 30 40 50
pF1KE2 MAGLGHPA-AFGRATHAVVRALPESLGQHALRSAKGEEVDVARAERQHQLYVGVLGSKLG
.: :. ..:: .::..:..::::.. .: .:.:.:.:.: . : : ..::
NP_001 MGTPGEGLGRCSHALIRGVPESLASGEGAGAGLPALDLAKAQREHGVLGGKLRQRLG
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 LQVVELPADESLPDCVFVEDVAVVCEETALITRPGAPSRRKEVDMMKEALEKLQLNIVEM
::..::: .:::: .. :.::. .::::::: .:.:: ::: ...::. : : :::.
NP_001 LQLLELPPEESLPLGPLLGDTAVIQGDTALITRPWSPARRPEVDGVRKALQDLGLRIVEI
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE2 KDENATLDGGDVLFTGREFFVGLSKRTNQRGAEILADTFKDYAVSTVPVADGLHLKSFCS
:::::::: ::::::::::::::: ::.:::::.::::.:.:::::::. ::...:.
NP_001 GDENATLDGTDVLFTGREFFVGLSKWTNHRGAEIVADTFRDFAVSTVPVSGPSHLRGLCG
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE2 MAGPNLIAIGSSESAQKALKIMQQMSDHRYDKLTVPDDIAANCIYL--NIPNKGHVLLHR
:.:: .. :::..::::.. : ..:: : .::.::: ::.:..: ..:. ::::
NP_001 MGGPRTVVAGSSDAAQKAVRAMAVLTDHPYASLTLPDDAAADCLFLRPGLPGVPPFLLHR
180 190 200 210 220 230
240 250 260 270 280
pF1KE2 TPEEYPESAKVYEKLKDHMLIPVSMSELEKVD-GLLTCCSVLINKKVDS
. :.: .. .::.: :.::: :::::. :: . : ::
NP_001 GGGDLPNSQEALQKLSDVTLVPVSCSELEKAGAGLSSLCLVLSTRPHS
240 250 260 270 280
285 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 03:36:28 2016 done: Tue Nov 8 03:36:29 2016
Total Scan time: 7.360 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]