Result of FASTA (omim) for
pFN21AE2485
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2485, 716 aa
1>>>pF1KE2485 716 - 716 aa - 716 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.5496+/-0.000381; mu= -4.7749+/- 0.024
mean_var=254.5541+/-52.543, 0's: 0 Z-trim(120.9): 58 B-trim: 53 in 2/55
Lambda= 0.080387
statistics sampled from 36612 (36691) to 36612 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.738), E-opt: 0.2 (0.43), width: 16
Scan time: 12.170
The best scores are: opt bits E(85289)
NP_765978 (OMIM: 600489) nuclear factor of activat ( 716) 4902 582.0 2.7e-165
NP_001265599 (OMIM: 600489) nuclear factor of acti ( 713) 4778 567.6 5.7e-161
NP_006153 (OMIM: 600489) nuclear factor of activat ( 825) 4771 566.9 1.1e-160
NP_001265598 (OMIM: 600489) nuclear factor of acti ( 943) 4771 566.9 1.3e-160
NP_001265604 (OMIM: 600489) nuclear factor of acti ( 703) 4621 549.4 1.7e-155
NP_001265601 (OMIM: 600489) nuclear factor of acti ( 700) 4497 535.1 3.7e-151
NP_765977 (OMIM: 600489) nuclear factor of activat ( 812) 4490 534.3 7.3e-151
NP_765975 (OMIM: 600489) nuclear factor of activat ( 930) 4490 534.3 8.2e-151
XP_016881272 (OMIM: 600489) PREDICTED: nuclear fac ( 639) 4324 515.0 3.7e-145
NP_775186 (OMIM: 602698) nuclear factor of activat (1065) 1850 228.2 1.3e-58
NP_004546 (OMIM: 602698) nuclear factor of activat (1068) 1850 228.2 1.3e-58
NP_775188 (OMIM: 602698) nuclear factor of activat (1075) 1850 228.2 1.4e-58
XP_016883340 (OMIM: 600490) PREDICTED: nuclear fac ( 695) 1729 214.0 1.6e-54
NP_036472 (OMIM: 600490) nuclear factor of activat ( 921) 1722 213.3 3.5e-54
NP_775114 (OMIM: 600490) nuclear factor of activat ( 925) 1722 213.3 3.5e-54
XP_011527126 (OMIM: 600490) PREDICTED: nuclear fac ( 940) 1722 213.3 3.6e-54
NP_001129493 (OMIM: 600490) nuclear factor of acti ( 901) 1708 211.7 1.1e-53
NP_001245221 (OMIM: 600490) nuclear factor of acti ( 905) 1708 211.7 1.1e-53
XP_011527127 (OMIM: 600490) PREDICTED: nuclear fac ( 920) 1708 211.7 1.1e-53
NP_001245225 (OMIM: 600490) nuclear factor of acti ( 702) 1597 198.7 6.4e-50
NP_001245223 (OMIM: 600490) nuclear factor of acti ( 702) 1597 198.7 6.4e-50
NP_001245226 (OMIM: 600490) nuclear factor of acti ( 706) 1597 198.7 6.4e-50
NP_001245224 (OMIM: 600490) nuclear factor of acti ( 706) 1597 198.7 6.4e-50
XP_011527128 (OMIM: 600490) PREDICTED: nuclear fac ( 721) 1597 198.7 6.6e-50
XP_016883339 (OMIM: 600490) PREDICTED: nuclear fac ( 721) 1597 198.7 6.6e-50
NP_765976 (OMIM: 600489) nuclear factor of activat ( 353) 1491 186.3 1.8e-46
NP_001265602 (OMIM: 600489) nuclear factor of acti ( 471) 1491 186.4 2.3e-46
NP_001185894 (OMIM: 602699) nuclear factor of acti ( 794) 1413 177.4 1.9e-43
NP_001185896 (OMIM: 602699) nuclear factor of acti ( 857) 1413 177.4 2e-43
NP_004545 (OMIM: 602699) nuclear factor of activat ( 902) 1413 177.4 2.1e-43
NP_001129494 (OMIM: 602699) nuclear factor of acti ( 964) 1413 177.5 2.2e-43
NP_001306972 (OMIM: 602699) nuclear factor of acti ( 965) 1413 177.5 2.2e-43
XP_011535101 (OMIM: 602699) PREDICTED: nuclear fac ( 782) 1400 175.9 5.3e-43
XP_011535100 (OMIM: 602699) PREDICTED: nuclear fac ( 879) 1400 175.9 5.9e-43
NP_001275731 (OMIM: 602699) nuclear factor of acti ( 889) 1400 175.9 5.9e-43
XP_011535099 (OMIM: 602699) PREDICTED: nuclear fac ( 890) 1400 175.9 5.9e-43
NP_001185895 (OMIM: 602699) nuclear factor of acti ( 832) 1385 174.2 1.9e-42
XP_016878361 (OMIM: 604708) PREDICTED: nuclear fac (1325) 774 103.4 5.9e-21
XP_011521121 (OMIM: 604708) PREDICTED: nuclear fac (1325) 774 103.4 5.9e-21
XP_011521122 (OMIM: 604708) PREDICTED: nuclear fac (1325) 774 103.4 5.9e-21
XP_011521124 (OMIM: 604708) PREDICTED: nuclear fac (1325) 774 103.4 5.9e-21
XP_016878362 (OMIM: 604708) PREDICTED: nuclear fac (1324) 770 103.0 8.2e-21
NP_775322 (OMIM: 604708) nuclear factor of activat (1455) 761 101.9 1.8e-20
NP_619728 (OMIM: 604708) nuclear factor of activat (1455) 761 101.9 1.8e-20
XP_011521120 (OMIM: 604708) PREDICTED: nuclear fac (1455) 761 101.9 1.8e-20
NP_775321 (OMIM: 604708) nuclear factor of activat (1455) 761 101.9 1.8e-20
XP_016878359 (OMIM: 604708) PREDICTED: nuclear fac (1455) 761 101.9 1.8e-20
XP_006721188 (OMIM: 604708) PREDICTED: nuclear fac (1484) 761 101.9 1.9e-20
NP_006590 (OMIM: 604708) nuclear factor of activat (1531) 761 102.0 1.9e-20
NP_619727 (OMIM: 604708) nuclear factor of activat (1549) 761 102.0 1.9e-20
>>NP_765978 (OMIM: 600489) nuclear factor of activated T (716 aa)
initn: 4902 init1: 4902 opt: 4902 Z-score: 3088.5 bits: 582.0 E(85289): 2.7e-165
Smith-Waterman score: 4902; 100.0% identity (100.0% similar) in 716 aa overlap (1-716:1-716)
10 20 30 40 50 60
pF1KE2 MPSTSFPVPSKFPLGPAAAVFGRGETLGPAPRAGGTMKSAEEEHYGYASSNVSPALPLPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_765 MPSTSFPVPSKFPLGPAAAVFGRGETLGPAPRAGGTMKSAEEEHYGYASSNVSPALPLPT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 AHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_765 AHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 EITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_765 EITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 SCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_765 SCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPST
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 SPRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_765 SPRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 LGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_765 LGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 PPPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_765 PPPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 SHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_765 SHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 ADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_765 ADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 NSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_765 NSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 QSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_765 QSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEI
610 620 630 640 650 660
670 680 690 700 710
pF1KE2 PPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANGNAIFLTVSREHERVGCFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_765 PPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANGNAIFLTVSREHERVGCFF
670 680 690 700 710
>>NP_001265599 (OMIM: 600489) nuclear factor of activate (713 aa)
initn: 4902 init1: 4778 opt: 4778 Z-score: 3010.9 bits: 567.6 E(85289): 5.7e-161
Smith-Waterman score: 4778; 99.7% identity (99.7% similar) in 701 aa overlap (1-701:1-701)
10 20 30 40 50 60
pF1KE2 MPSTSFPVPSKFPLGPAAAVFGRGETLGPAPRAGGTMKSAEEEHYGYASSNVSPALPLPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPSTSFPVPSKFPLGPAAAVFGRGETLGPAPRAGGTMKSAEEEHYGYASSNVSPALPLPT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 AHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 EITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 SCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPST
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 SPRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 LGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 PPPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 SHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 ADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 NSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 QSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEI
610 620 630 640 650 660
670 680 690 700 710
pF1KE2 PPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANGNAIFLTVSREHERVGCFF
::::::::::::::::::::::::::::::::::::: : :
NP_001 PPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANVNEIIRNDLSSTSTHS
670 680 690 700 710
>>NP_006153 (OMIM: 600489) nuclear factor of activated T (825 aa)
initn: 4771 init1: 4771 opt: 4771 Z-score: 3005.5 bits: 566.9 E(85289): 1.1e-160
Smith-Waterman score: 4771; 100.0% identity (100.0% similar) in 697 aa overlap (1-697:1-697)
10 20 30 40 50 60
pF1KE2 MPSTSFPVPSKFPLGPAAAVFGRGETLGPAPRAGGTMKSAEEEHYGYASSNVSPALPLPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MPSTSFPVPSKFPLGPAAAVFGRGETLGPAPRAGGTMKSAEEEHYGYASSNVSPALPLPT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 AHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 AHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 EITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 EITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 SCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPST
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 SPRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SPRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 LGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 PPPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 PPPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 SHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 ADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 ADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 NSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 NSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 QSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 QSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEI
610 620 630 640 650 660
670 680 690 700 710
pF1KE2 PPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANGNAIFLTVSREHERVGCFF
:::::::::::::::::::::::::::::::::::::
NP_006 PPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANVPIIKTEPTDDYEPAPTCGPVSQ
670 680 690 700 710 720
NP_006 GLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKLHDLSPAAYTKGV
730 740 750 760 770 780
>>NP_001265598 (OMIM: 600489) nuclear factor of activate (943 aa)
initn: 4771 init1: 4771 opt: 4771 Z-score: 3004.6 bits: 566.9 E(85289): 1.3e-160
Smith-Waterman score: 4771; 100.0% identity (100.0% similar) in 697 aa overlap (1-697:1-697)
10 20 30 40 50 60
pF1KE2 MPSTSFPVPSKFPLGPAAAVFGRGETLGPAPRAGGTMKSAEEEHYGYASSNVSPALPLPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPSTSFPVPSKFPLGPAAAVFGRGETLGPAPRAGGTMKSAEEEHYGYASSNVSPALPLPT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 AHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 EITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 SCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPST
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 SPRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 LGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 PPPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 SHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 ADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 NSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 QSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEI
610 620 630 640 650 660
670 680 690 700 710
pF1KE2 PPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANGNAIFLTVSREHERVGCFF
:::::::::::::::::::::::::::::::::::::
NP_001 PPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANVPIIKTEPTDDYEPAPTCGPVSQ
670 680 690 700 710 720
NP_001 GLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKLHDLSPAAYTKGV
730 740 750 760 770 780
>>NP_001265604 (OMIM: 600489) nuclear factor of activate (703 aa)
initn: 4621 init1: 4621 opt: 4621 Z-score: 2912.5 bits: 549.4 E(85289): 1.7e-155
Smith-Waterman score: 4621; 99.6% identity (99.7% similar) in 678 aa overlap (39-716:26-703)
10 20 30 40 50 60
pF1KE2 PSKFPLGPAAAVFGRGETLGPAPRAGGTMKSAEEEHYGYASSNVSPALPLPTAHSTLPAP
.: ::::::::::::::::::::::::::
NP_001 MTGLEDQEFDFEFLFEFNQRDEGAAAAAPEHYGYASSNVSPALPLPTAHSTLPAP
10 20 30 40 50
70 80 90 100 110 120
pF1KE2 CHNLQTSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRIEITSCLGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CHNLQTSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRIEITSCLGL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE2 YHNNNQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YHNNNQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASS
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE2 YESNYSYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YESNYSYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTE
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE2 ESWLGARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSWLGNTTQYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESWLGARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSWLGNTTQYT
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE2 SSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPPPPADFAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPPPPADFAP
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE2 EDYSSFQHIRKGGFCDQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLPSHSGPYEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDYSSFQHIRKGGFCDQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLPSHSGPYEL
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE2 RIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGTADDRLLRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGTADDRLLRP
420 430 440 450 460 470
490 500 510 520 530 540
pF1KE2 HAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLRNSDIELRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLRNSDIELRK
480 490 500 510 520 530
550 560 570 580 590 600
pF1KE2 GETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEKQSTDSYPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEKQSTDSYPV
540 550 560 570 580 590
610 620 630 640 650 660
pF1KE2 VGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEIPPFRNQRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEIPPFRNQRI
600 610 620 630 640 650
670 680 690 700 710
pF1KE2 TSPVHVSFYVCNGKRKRSQYQRFTYLPANGNAIFLTVSREHERVGCFF
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSPVHVSFYVCNGKRKRSQYQRFTYLPANGNAIFLTVSREHERVGCFF
660 670 680 690 700
>>NP_001265601 (OMIM: 600489) nuclear factor of activate (700 aa)
initn: 4617 init1: 4493 opt: 4497 Z-score: 2834.8 bits: 535.1 E(85289): 3.7e-151
Smith-Waterman score: 4497; 99.2% identity (99.4% similar) in 663 aa overlap (39-701:26-688)
10 20 30 40 50 60
pF1KE2 PSKFPLGPAAAVFGRGETLGPAPRAGGTMKSAEEEHYGYASSNVSPALPLPTAHSTLPAP
.: ::::::::::::::::::::::::::
NP_001 MTGLEDQEFDFEFLFEFNQRDEGAAAAAPEHYGYASSNVSPALPLPTAHSTLPAP
10 20 30 40 50
70 80 90 100 110 120
pF1KE2 CHNLQTSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRIEITSCLGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CHNLQTSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRIEITSCLGL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE2 YHNNNQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YHNNNQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASS
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE2 YESNYSYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YESNYSYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTE
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE2 ESWLGARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSWLGNTTQYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESWLGARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSWLGNTTQYT
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE2 SSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPPPPADFAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPPPPADFAP
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE2 EDYSSFQHIRKGGFCDQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLPSHSGPYEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDYSSFQHIRKGGFCDQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLPSHSGPYEL
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE2 RIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGTADDRLLRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGTADDRLLRP
420 430 440 450 460 470
490 500 510 520 530 540
pF1KE2 HAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLRNSDIELRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLRNSDIELRK
480 490 500 510 520 530
550 560 570 580 590 600
pF1KE2 GETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEKQSTDSYPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEKQSTDSYPV
540 550 560 570 580 590
610 620 630 640 650 660
pF1KE2 VGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEIPPFRNQRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEIPPFRNQRI
600 610 620 630 640 650
670 680 690 700 710
pF1KE2 TSPVHVSFYVCNGKRKRSQYQRFTYLPANGNAIFLTVSREHERVGCFF
::::::::::::::::::::::::::::: : :
NP_001 TSPVHVSFYVCNGKRKRSQYQRFTYLPANVNEIIRNDLSSTSTHS
660 670 680 690 700
>>NP_765977 (OMIM: 600489) nuclear factor of activated T (812 aa)
initn: 4490 init1: 4490 opt: 4490 Z-score: 2829.5 bits: 534.3 E(85289): 7.3e-151
Smith-Waterman score: 4490; 99.5% identity (99.7% similar) in 659 aa overlap (39-697:26-684)
10 20 30 40 50 60
pF1KE2 PSKFPLGPAAAVFGRGETLGPAPRAGGTMKSAEEEHYGYASSNVSPALPLPTAHSTLPAP
.: ::::::::::::::::::::::::::
NP_765 MTGLEDQEFDFEFLFEFNQRDEGAAAAAPEHYGYASSNVSPALPLPTAHSTLPAP
10 20 30 40 50
70 80 90 100 110 120
pF1KE2 CHNLQTSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRIEITSCLGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_765 CHNLQTSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRIEITSCLGL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE2 YHNNNQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_765 YHNNNQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASS
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE2 YESNYSYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_765 YESNYSYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTE
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE2 ESWLGARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSWLGNTTQYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_765 ESWLGARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSWLGNTTQYT
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE2 SSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPPPPADFAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_765 SSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPPPPADFAP
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE2 EDYSSFQHIRKGGFCDQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLPSHSGPYEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_765 EDYSSFQHIRKGGFCDQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLPSHSGPYEL
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE2 RIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGTADDRLLRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_765 RIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGTADDRLLRP
420 430 440 450 460 470
490 500 510 520 530 540
pF1KE2 HAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLRNSDIELRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_765 HAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLRNSDIELRK
480 490 500 510 520 530
550 560 570 580 590 600
pF1KE2 GETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEKQSTDSYPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_765 GETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEKQSTDSYPV
540 550 560 570 580 590
610 620 630 640 650 660
pF1KE2 VGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEIPPFRNQRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_765 VGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEIPPFRNQRI
600 610 620 630 640 650
670 680 690 700 710
pF1KE2 TSPVHVSFYVCNGKRKRSQYQRFTYLPANGNAIFLTVSREHERVGCFF
:::::::::::::::::::::::::::::
NP_765 TSPVHVSFYVCNGKRKRSQYQRFTYLPANVPIIKTEPTDDYEPAPTCGPVSQGLSPLPRP
660 670 680 690 700 710
>>NP_765975 (OMIM: 600489) nuclear factor of activated T (930 aa)
initn: 4490 init1: 4490 opt: 4490 Z-score: 2828.6 bits: 534.3 E(85289): 8.2e-151
Smith-Waterman score: 4490; 99.5% identity (99.7% similar) in 659 aa overlap (39-697:26-684)
10 20 30 40 50 60
pF1KE2 PSKFPLGPAAAVFGRGETLGPAPRAGGTMKSAEEEHYGYASSNVSPALPLPTAHSTLPAP
.: ::::::::::::::::::::::::::
NP_765 MTGLEDQEFDFEFLFEFNQRDEGAAAAAPEHYGYASSNVSPALPLPTAHSTLPAP
10 20 30 40 50
70 80 90 100 110 120
pF1KE2 CHNLQTSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRIEITSCLGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_765 CHNLQTSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRIEITSCLGL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE2 YHNNNQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_765 YHNNNQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASS
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE2 YESNYSYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_765 YESNYSYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTE
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE2 ESWLGARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSWLGNTTQYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_765 ESWLGARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSWLGNTTQYT
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE2 SSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPPPPADFAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_765 SSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPPPPADFAP
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE2 EDYSSFQHIRKGGFCDQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLPSHSGPYEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_765 EDYSSFQHIRKGGFCDQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLPSHSGPYEL
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE2 RIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGTADDRLLRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_765 RIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGTADDRLLRP
420 430 440 450 460 470
490 500 510 520 530 540
pF1KE2 HAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLRNSDIELRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_765 HAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLRNSDIELRK
480 490 500 510 520 530
550 560 570 580 590 600
pF1KE2 GETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEKQSTDSYPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_765 GETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEKQSTDSYPV
540 550 560 570 580 590
610 620 630 640 650 660
pF1KE2 VGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEIPPFRNQRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_765 VGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEIPPFRNQRI
600 610 620 630 640 650
670 680 690 700 710
pF1KE2 TSPVHVSFYVCNGKRKRSQYQRFTYLPANGNAIFLTVSREHERVGCFF
:::::::::::::::::::::::::::::
NP_765 TSPVHVSFYVCNGKRKRSQYQRFTYLPANVPIIKTEPTDDYEPAPTCGPVSQGLSPLPRP
660 670 680 690 700 710
>>XP_016881272 (OMIM: 600489) PREDICTED: nuclear factor (639 aa)
initn: 4448 init1: 4324 opt: 4324 Z-score: 2727.0 bits: 515.0 E(85289): 3.7e-145
Smith-Waterman score: 4324; 99.8% identity (100.0% similar) in 635 aa overlap (1-635:1-635)
10 20 30 40 50 60
pF1KE2 MPSTSFPVPSKFPLGPAAAVFGRGETLGPAPRAGGTMKSAEEEHYGYASSNVSPALPLPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPSTSFPVPSKFPLGPAAAVFGRGETLGPAPRAGGTMKSAEEEHYGYASSNVSPALPLPT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 AHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 EITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 SCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPST
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 SPRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 LGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 PPPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 SHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 ADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 NSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 QSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEI
::::::::::::::::::::::::::::::::::.
XP_016 QSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPEFSGG
610 620 630
670 680 690 700 710
pF1KE2 PPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANGNAIFLTVSREHERVGCFF
>>NP_775186 (OMIM: 602698) nuclear factor of activated T (1065 aa)
initn: 1893 init1: 1069 opt: 1850 Z-score: 1173.0 bits: 228.2 E(85289): 1.3e-58
Smith-Waterman score: 1944; 48.9% identity (67.5% similar) in 699 aa overlap (24-695:19-699)
10 20 30 40 50 60
pF1KE2 MPSTSFPVPSKFPLGPAAAVFGRGETLGPAPRAGGTMKSAEEEHYGYASSNVSPALPLPT
:: .::: :. . :. : :: . . : :.
NP_775 MTTANCGAHDELDFKLVFGEDGAPAPPPPGS-RPADLEPDDCASIYIFNVDPPPS
10 20 30 40 50
70 80 90 100 110
pF1KE2 AHST-LPAPCHNLQTSTPGIIPPA----DHPSGYGAALDGGPAGYFLSSGHTRPDGAPAL
. .: : : :.: . . ... :. .: . :. : . . : .: .
NP_775 TLTTPLCLPHHGLPSHS-SVLSPSFQLQSHKNYEGTCEI--PESKYSPLGGPKP-----F
60 70 80 90 100
120 130 140 150 160 170
pF1KE2 ESPRIEITSCLGLYHNN-NQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCL-SP
: : :.::: :.. . :....: . :: : :: .::. : ::
NP_775 ECPSIQITSISPNCHQELDAHEDDLQINDPEREFLERPSRDHLYLPLEPSYRESSLSPSP
110 120 130 140 150 160
180 190 200 210 220
pF1KE2 ASSLSSRSCNSEASSYESNYSYPYASPQT------------SPWQSPCVSPKTTDPEEGF
:::.:::: :.::: :: :. : . .. :: :: :: :: .
NP_775 ASSISSRSWFSDASSCES-LSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCPGEETW
170 180 190 200 210 220
230 240 250 260 270
pF1KE2 PRGLGACTLLGSPRHSPSTSPRASVTEESWLGAR-----SSRPASPCNKRKYSLNG--RQ
. : : :::.:: :::.:::.:.::. : ::::.:::.::..:
NP_775 HQQYGLGHSL-SPRQSPCHSPRSSVTDENWLSPRPASGPSSRPTSPCGKRRHSSAEVCYA
230 240 250 260 270 280
280 290 300 310 320 330
pF1KE2 PPYSPHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVK
::::::.::: ::: :::.:.:: :.. . .:.. :. . : .:.:
NP_775 GSLSPHHSPVPSPGHSPRGSVTEDTWL-NASVHGGSGLGPAVFPFQYCVETD----IPLK
290 300 310 320 330
340 350 360 370 380 390
pF1KE2 SRKTTLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSSFQHIRKGGFC-DQYLAVPQHP
.:::. .: . :.: ..: :: : . . .: . :. : : ::.:.::. :
NP_775 TRKTSEDQAAILPGKLELCSDDQGSLSPARETSIDDGLGSQYPLKKDSCGDQFLSVPS-P
340 350 360 370 380 390
400 410 420 430 440 450
pF1KE2 YQWAKPKPLSPTSYMSPTLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKA
. :.:::: . . .:: ::: ::.: : ::.::::::.:::::::::::::::::
NP_775 FTWSKPKPGHTPIFRTSSLPPLDWPLPAHFGQCELKIEVQPKTHHRAHYETEGSRGAVKA
400 410 420 430 440 450
460 470 480 490 500 510
pF1KE2 SAGGHPIVQLHGYLENEPLMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSN
:.::::.:.: :: : .:. ::.:::::::: :::::::::::::::::.:.:.: :...
NP_775 STGGHPVVKLLGYNE-KPINLQMFIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIAS
460 470 480 490 500 510
520 530 540 550 560 570
pF1KE2 TKVLEIPLLPENSMRAVIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSG
::::::::::::.: : :::::::::::::::::::::::::::::::::::::.:::::
NP_775 TKVLEIPLLPENNMSASIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSG
520 530 540 550 560 570
580 590 600 610 620 630
pF1KE2 RTLSLQVASNPIECSQRSAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKA
..::::.:: :.::::::::::: .:: : .: : ::..::..: ::: .::.::.::.
NP_775 KVLSLQIASIPVECSQRSAQELPHIEKYSINSCSVNGGHEMVVTGSNFLPESKIIFLEKG
580 590 600 610 620 630
640 650 660 670 680 690
pF1KE2 PDGHHVWEMEAKTDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTY
::. ::.:.: :. :. .:.:.::..: .:. :.: ::.::::::.:: :::::
NP_775 QDGRPQWEVEGKIIREKCQGAHIVLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTY
640 650 660 670 680 690
700 710
pF1KE2 LPANGNAIFLTVSREHERVGCFF
:
NP_775 TPVLMKQEHREEIDLSSVPSLPVPHPAQTQRPSSDSGCSHDSVLSGQRSLICSIPQTYAS
700 710 720 730 740 750
716 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 20:47:14 2016 done: Mon Nov 7 20:47:16 2016
Total Scan time: 12.170 Total Display time: 0.200
Function used was FASTA [36.3.4 Apr, 2011]