Result of FASTA (ccds) for
pFN21AE2482
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2482, 468 aa
1>>>pF1KE2482 468 - 468 aa - 468 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.5471+/-0.000954; mu= 12.7106+/- 0.058
mean_var=100.3500+/-19.813, 0's: 0 Z-trim(107.6): 124 B-trim: 3 in 1/50
Lambda= 0.128031
statistics sampled from 9522 (9648) to 9522 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.665), E-opt: 0.2 (0.296), width: 16
Scan time: 2.340
The best scores are: opt bits E(32554)
CCDS45271.1 RORA gene_id:6095|Hs108|chr15 ( 468) 3180 597.9 7.3e-171
CCDS10178.1 RORA gene_id:6095|Hs108|chr15 ( 548) 3129 588.5 5.7e-168
CCDS10179.1 RORA gene_id:6095|Hs108|chr15 ( 556) 3124 587.6 1.1e-167
CCDS10177.1 RORA gene_id:6095|Hs108|chr15 ( 523) 3113 585.6 4.2e-167
CCDS6646.1 RORB gene_id:6096|Hs108|chr9 ( 459) 1971 374.6 1.2e-103
CCDS30856.1 RORC gene_id:6097|Hs108|chr1 ( 497) 950 186.0 7.5e-47
CCDS1004.1 RORC gene_id:6097|Hs108|chr1 ( 518) 950 186.0 7.8e-47
CCDS11361.1 NR1D1 gene_id:9572|Hs108|chr17 ( 614) 438 91.5 2.7e-18
CCDS33718.1 NR1D2 gene_id:9975|Hs108|chr3 ( 579) 428 89.7 9.1e-18
CCDS6856.1 NR5A1 gene_id:2516|Hs108|chr9 ( 461) 419 87.9 2.4e-17
CCDS2642.1 RARB gene_id:5915|Hs108|chr3 ( 448) 417 87.6 3e-17
CCDS58236.1 RARG gene_id:5916|Hs108|chr12 ( 382) 415 87.2 3.4e-17
CCDS41790.1 RARG gene_id:5916|Hs108|chr12 ( 443) 415 87.2 3.8e-17
CCDS8850.1 RARG gene_id:5916|Hs108|chr12 ( 454) 415 87.2 3.9e-17
CCDS42317.1 RARA gene_id:5914|Hs108|chr17 ( 457) 407 85.7 1.1e-16
CCDS11366.1 RARA gene_id:5914|Hs108|chr17 ( 462) 407 85.7 1.1e-16
CCDS41821.1 NR2C1 gene_id:7181|Hs108|chr12 ( 467) 399 84.2 3.1e-16
CCDS44953.1 NR2C1 gene_id:7181|Hs108|chr12 ( 483) 399 84.3 3.2e-16
CCDS9051.1 NR2C1 gene_id:7181|Hs108|chr12 ( 603) 399 84.3 3.8e-16
CCDS35172.1 RXRA gene_id:6256|Hs108|chr9 ( 462) 397 83.9 4e-16
CCDS2610.2 PPARG gene_id:5468|Hs108|chr3 ( 477) 389 82.4 1.1e-15
CCDS2609.1 PPARG gene_id:5468|Hs108|chr3 ( 505) 389 82.4 1.2e-15
CCDS72970.1 RXRG gene_id:6258|Hs108|chr1 ( 340) 385 81.6 1.4e-15
CCDS1248.1 RXRG gene_id:6258|Hs108|chr1 ( 463) 385 81.7 1.9e-15
CCDS4768.1 RXRB gene_id:6257|Hs108|chr6 ( 533) 385 81.7 2.1e-15
CCDS59007.1 RXRB gene_id:6257|Hs108|chr6 ( 537) 385 81.7 2.1e-15
CCDS60383.1 NR5A2 gene_id:2494|Hs108|chr1 ( 469) 380 80.7 3.6e-15
CCDS1400.1 NR5A2 gene_id:2494|Hs108|chr1 ( 495) 380 80.7 3.7e-15
CCDS1401.1 NR5A2 gene_id:2494|Hs108|chr1 ( 541) 380 80.8 4e-15
CCDS10375.1 NR2F2 gene_id:7026|Hs108|chr15 ( 414) 378 80.3 4.1e-15
CCDS4068.1 NR2F1 gene_id:7025|Hs108|chr5 ( 423) 378 80.3 4.2e-15
CCDS33669.1 PPARA gene_id:5465|Hs108|chr22 ( 468) 377 80.2 5.2e-15
CCDS6743.1 NR4A3 gene_id:8013|Hs108|chr9 ( 626) 374 79.7 9.8e-15
CCDS6742.1 NR4A3 gene_id:8013|Hs108|chr9 ( 637) 374 79.7 9.9e-15
CCDS4804.1 PPARD gene_id:5467|Hs108|chr6 ( 361) 369 78.6 1.2e-14
CCDS54994.1 PPARD gene_id:5467|Hs108|chr6 ( 402) 369 78.7 1.3e-14
CCDS4803.1 PPARD gene_id:5467|Hs108|chr6 ( 441) 369 78.7 1.4e-14
CCDS6744.1 NR4A3 gene_id:8013|Hs108|chr9 ( 443) 363 77.6 3e-14
CCDS12352.1 NR2F6 gene_id:2063|Hs108|chr19 ( 404) 362 77.4 3.1e-14
CCDS42316.1 THRA gene_id:7067|Hs108|chr17 ( 410) 361 77.2 3.6e-14
CCDS58546.1 THRA gene_id:7067|Hs108|chr17 ( 451) 361 77.2 3.9e-14
CCDS55340.1 NR6A1 gene_id:2649|Hs108|chr9 ( 475) 361 77.2 4.1e-14
CCDS65127.1 NR6A1 gene_id:2649|Hs108|chr9 ( 476) 361 77.2 4.1e-14
CCDS35137.1 NR6A1 gene_id:2649|Hs108|chr9 ( 480) 361 77.2 4.1e-14
CCDS11360.1 THRA gene_id:7067|Hs108|chr17 ( 490) 361 77.2 4.2e-14
CCDS5063.1 NR2E1 gene_id:7101|Hs108|chr6 ( 385) 355 76.1 7.4e-14
CCDS2641.1 THRB gene_id:7068|Hs108|chr3 ( 461) 354 75.9 9.8e-14
CCDS69165.1 NR2E1 gene_id:7101|Hs108|chr6 ( 422) 353 75.7 1e-13
CCDS2201.1 NR4A2 gene_id:4929|Hs108|chr2 ( 598) 351 75.4 1.8e-13
CCDS74905.1 NR2C2 gene_id:7182|Hs108|chr3 ( 596) 349 75.1 2.3e-13
>>CCDS45271.1 RORA gene_id:6095|Hs108|chr15 (468 aa)
initn: 3180 init1: 3180 opt: 3180 Z-score: 3181.1 bits: 597.9 E(32554): 7.3e-171
Smith-Waterman score: 3180; 100.0% identity (100.0% similar) in 468 aa overlap (1-468:1-468)
10 20 30 40 50 60
pF1KE2 MMYFVIAAMKAQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 MMYFVIAAMKAQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 LIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 PGEAEPLTPTYNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 PGEAEPLTPTYNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 INGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 INGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREEL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 QQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 QQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 LKAGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 LKAGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 TEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 TEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVS
370 380 390 400 410 420
430 440 450 460
pF1KE2 TLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG
::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 TLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG
430 440 450 460
>>CCDS10178.1 RORA gene_id:6095|Hs108|chr15 (548 aa)
initn: 3127 init1: 3127 opt: 3129 Z-score: 3129.1 bits: 588.5 E(32554): 5.7e-168
Smith-Waterman score: 3129; 98.9% identity (99.6% similar) in 466 aa overlap (4-468:83-548)
10 20 30
pF1KE2 MMYFVIAAM-KAQIEIIPCKICGDKSSGIHYGV
:.. :. :::::::::::::::::::::::
CCDS10 LSRLFWSQLEHINWDGATAKNFINLREFFSFLLPALRKAQIEIIPCKICGDKSSGIHYGV
60 70 80 90 100 110
40 50 60 70 80 90
pF1KE2 ITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 ITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGR
120 130 140 150 160 170
100 110 120 130 140 150
pF1KE2 MSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISANGLTELHDDLSNYIDGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 MSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISANGLTELHDDLSNYIDGH
180 190 200 210 220 230
160 170 180 190 200 210
pF1KE2 TPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 TPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPT
240 250 260 270 280 290
220 230 240 250 260 270
pF1KE2 VSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 VSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKI
300 310 320 330 340 350
280 290 300 310 320 330
pF1KE2 TEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 TEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYAS
360 370 380 390 400 410
340 350 360 370 380 390
pF1KE2 PDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 PDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQ
420 430 440 450 460 470
400 410 420 430 440 450
pF1KE2 KIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 KIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLY
480 490 500 510 520 530
460
pF1KE2 KELFTSEFEPAMQIDG
::::::::::::::::
CCDS10 KELFTSEFEPAMQIDG
540
>>CCDS10179.1 RORA gene_id:6095|Hs108|chr15 (556 aa)
initn: 3124 init1: 3124 opt: 3124 Z-score: 3124.0 bits: 587.6 E(32554): 1.1e-167
Smith-Waterman score: 3124; 99.8% identity (100.0% similar) in 460 aa overlap (9-468:97-556)
10 20 30
pF1KE2 MMYFVIAAMKAQIEIIPCKICGDKSSGIHYGVITCEGC
:.::::::::::::::::::::::::::::
CCDS10 FVLTGVCCSWRQNGKPPYSQKEDKEVQTGYMNAQIEIIPCKICGDKSSGIHYGVITCEGC
70 80 90 100 110 120
40 50 60 70 80 90
pF1KE2 KGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 KGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQR
130 140 150 160 170 180
100 110 120 130 140 150
pF1KE2 DSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISANGLTELHDDLSNYIDGHTPEGSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 DSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISANGLTELHDDLSNYIDGHTPEGSK
190 200 210 220 230 240
160 170 180 190 200 210
pF1KE2 ADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 ADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAEL
250 260 270 280 290 300
220 230 240 250 260 270
pF1KE2 EHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 EHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQY
310 320 330 340 350 360
280 290 300 310 320 330
pF1KE2 VVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 VVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKS
370 380 390 400 410 420
340 350 360 370 380 390
pF1KE2 LGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 LGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLAL
430 440 450 460 470 480
400 410 420 430 440 450
pF1KE2 QHVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 QHVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTS
490 500 510 520 530 540
460
pF1KE2 EFEPAMQIDG
::::::::::
CCDS10 EFEPAMQIDG
550
>>CCDS10177.1 RORA gene_id:6095|Hs108|chr15 (523 aa)
initn: 3113 init1: 3113 opt: 3113 Z-score: 3113.4 bits: 585.6 E(32554): 4.2e-167
Smith-Waterman score: 3113; 99.8% identity (100.0% similar) in 458 aa overlap (11-468:66-523)
10 20 30 40
pF1KE2 MMYFVIAAMKAQIEIIPCKICGDKSSGIHYGVITCEGCKG
.:::::::::::::::::::::::::::::
CCDS10 ARKSEPPAPVRRQSYSSTSRGISVTKKTHTSQIEIIPCKICGDKSSGIHYGVITCEGCKG
40 50 60 70 80 90
50 60 70 80 90 100
pF1KE2 FFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 FFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDS
100 110 120 130 140 150
110 120 130 140 150 160
pF1KE2 LYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISANGLTELHDDLSNYIDGHTPEGSKAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 LYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISANGLTELHDDLSNYIDGHTPEGSKAD
160 170 180 190 200 210
170 180 190 200 210 220
pF1KE2 SAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 SAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEH
220 230 240 250 260 270
230 240 250 260 270 280
pF1KE2 LAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 LAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVV
280 290 300 310 320 330
290 300 310 320 330 340
pF1KE2 EFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKSLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 EFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKSLG
340 350 360 370 380 390
350 360 370 380 390 400
pF1KE2 CEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 CEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQH
400 410 420 430 440 450
410 420 430 440 450 460
pF1KE2 VLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 VLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSEF
460 470 480 490 500 510
pF1KE2 EPAMQIDG
::::::::
CCDS10 EPAMQIDG
520
>>CCDS6646.1 RORB gene_id:6096|Hs108|chr9 (459 aa)
initn: 1833 init1: 1137 opt: 1971 Z-score: 1974.3 bits: 374.6 E(32554): 1.2e-103
Smith-Waterman score: 1971; 63.9% identity (85.1% similar) in 457 aa overlap (9-459:1-453)
10 20 30 40 50 60
pF1KE2 MMYFVIAAMKAQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNC
:.::::.::::::::::::::::::::::::::::::::.::.::::::.::
CCDS66 MRAQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYSCPRQRNC
10 20 30 40 50
70 80 90 100 110 120
pF1KE2 LIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQ
:::::.::::::::::::::.:::::::::::::::::::::::::::. :. :...:::
CCDS66 LIDRTNRNRCQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLYAEVQKHQ-QRLQEQRQQQ
60 70 80 90 100 110
130 140 150 160 170
pF1KE2 PGEAEPLTPTYNIS-ANGLTELHDDLSN-YIDGHTPEGSKADSAVSSFYLDI-QPSPDQS
:::: :. .:. : .:::..:... :. : .::. . :... . .: :::::::
CCDS66 SGEAEALARVYSSSISNGLSNLNNETSGTYANGHVIDLPKSEGY---YNVDSGQPSPDQS
120 130 140 150 160
180 190 200 210 220 230
pF1KE2 GLDINGIKP---EPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQ
:::..::: ::: : : . ..: : ::.::. .: ..:.:....:::: ::::::::
CCDS66 GLDMTGIKQIKQEPIYDLTSVPNLFTYSSFNNGQLAPGITMTEIDRIAQNIIKSHLETCQ
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE2 YLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQ
: :::.:..::: :::. ::.:.::..:: :::.::.:::::::::::: :::::::
CCDS66 YTMEELHQLAWQTHTYEEIKAYQSKSREALWQQCAIQITHAIQYVVEFAKRITGFMELCQ
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE2 NDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKS
::::.:::.: ::::..::::::. :::: :.:::.. ..::.:: .:... .:.:.:.
CCDS66 NDQILLLKSGCLEVVLVRMCRAFNPLNNTVLFEGKYGGMQMFKALGSDDLVNEAFDFAKN
290 300 310 320 330 340
360 370 380 390 400 410
pF1KE2 LCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTK
:::..:::.::::::. ::.: ::.:: : :..:::.:: .:::::.:::: .: :.:
CCDS66 LCSLQLTEEEIALFSSAVLISPDRAWLIEPRKVQKLQEKIYFALQHVIQKNHLDDETLAK
350 360 370 380 390 400
420 430 440 450 460
pF1KE2 LICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG
:: :. :. :.:. : :::..:: .:.:: :::::::::. .
CCDS66 LIAKIPTITAVCNLHGEKLQVFKQSHPEIVNTLFPPLYKELFNPDCATGCK
410 420 430 440 450
>>CCDS30856.1 RORC gene_id:6097|Hs108|chr1 (497 aa)
initn: 1634 init1: 785 opt: 950 Z-score: 954.6 bits: 186.0 E(32554): 7.5e-47
Smith-Waterman score: 1539; 49.6% identity (73.0% similar) in 492 aa overlap (9-461:1-490)
10 20 30 40 50 60
pF1KE2 MMYFVIAAMKAQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNC
:..:::.:::::::::::::::::::::::::::::::. ::.::: ::.::
CCDS30 MRTQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQRCNAAYSCTRQQNC
10 20 30 40 50
70 80 90 100 110
pF1KE2 LIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQ--
:::::::::::::::::::.::::::::::::::::::::.:::::. .:.::....
CCDS30 PIDRTSRNRCQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLHAEVQKQLQQRQQQQQEPV
60 70 80 90 100 110
120 130 140
pF1KE2 -----------------------QQPGEAEPLTPTYNISANGLTELHDDLSNY-------
: : . : : . :: . . .:
CCDS30 VKTPPAGAQGADTLTYTLGLPDGQLPLGSSPDLPEASACPPGLLKASGSGPSYSNNLAKA
120 130 140 150 160 170
150 160 170 180 190 200
pF1KE2 -IDG------HTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPY
..: ..:: .::.. : . : .::. :: .. . . . . .
CCDS30 GLNGASCHLEYSPERGKAEGRESFYSTGSQLTPDRCGLRFEEHRHPGLGELGQGPDSYGS
180 190 200 210 220 230
210 220 230 240 250 260
pF1KE2 CSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQR
:: . .: .:..:.:::.:.. ::. :::: :.: . . : .::. .:: :.
CCDS30 PSFRSTPEAPYASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSM
240 250 260 270 280 290
270 280 290 300 310 320
pF1KE2 EVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQN
::. :: ..:::::::::::::..:::::::::::::::::..:::..:::::....:
CCDS30 WEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADN
300 310 320 330 340 350
330 340 350 360 370 380
pF1KE2 NTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWL
::.:.:::.. ..:..::: ..:: .:.:..:: ..:..::::::..:.::..: : :
CCDS30 RTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGL
360 370 380 390 400 410
390 400 410 420 430 440
pF1KE2 QEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYP
::: :.:.:: ...::..: : :.::.. ::.:: : . ::.::..:.:.:. :. ..:
CCDS30 QEKRKVEQLQYNLELAFHHHLCKTHRQS-ILAKLPPK-GKLRSLCSQHVERLQIFQHLHP
420 430 440 450 460 470
450 460
pF1KE2 DIVRLHFPPLYKELFTSEFEPAMQIDG
.:. :::::::::..: :
CCDS30 IVVQAAFPPLYKELFSTETESPVGLSK
480 490
>>CCDS1004.1 RORC gene_id:6097|Hs108|chr1 (518 aa)
initn: 1625 init1: 785 opt: 950 Z-score: 954.3 bits: 186.0 E(32554): 7.8e-47
Smith-Waterman score: 1530; 49.6% identity (72.9% similar) in 490 aa overlap (11-461:24-511)
10 20 30 40
pF1KE2 MMYFVIAAMKAQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQ
.:::.:::::::::::::::::::::::::::::::.
CCDS10 MDRAPQRQHRASRELLAAKKTHTSQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQR
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE2 SNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQK
::.::: ::.:: :::::::::::::::::::.::::::::::::::::::::.:::::
CCDS10 CNAAYSCTRQQNCPIDRTSRNRCQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLHAEVQK
70 80 90 100 110 120
110 120 130 140
pF1KE2 HRMQQQQRDHQ-------------------------QQPGEAEPLTPTYNISANGLTELH
. .:.::.... : : . : : . :: .
CCDS10 QLQQRQQQQQEPVVKTPPAGAQGADTLTYTLGLPDGQLPLGSSPDLPEASACPPGLLKAS
130 140 150 160 170 180
150 160 170 180
pF1KE2 DDLSNY--------IDG------HTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEP
. .: ..: ..:: .::.. : . : .::. :: .. .
CCDS10 GSGPSYSNNLAKAGLNGASCHLEYSPERGKAEGRESFYSTGSQLTPDRCGLRFEEHRHPG
190 200 210 220 230 240
190 200 210 220 230 240
pF1KE2 ICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQITWQTF
. . . . :: . .: .:..:.:::.:.. ::. :::: :.: . . :
CCDS10 LGELGQGPDSYGSPSFRSTPEAPYASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIF
250 260 270 280 290 300
250 260 270 280 290 300
pF1KE2 LQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEV
.::. .:: :. ::. :: ..:::::::::::::..:::::::::::::::::..::
CCDS10 SREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEV
310 320 330 340 350 360
310 320 330 340 350 360
pF1KE2 VFIRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALF
:..:::::....: ::.:.:::.. ..:..::: ..:: .:.:..:: ..:..::::::.
CCDS10 VLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALY
370 380 390 400 410 420
370 380 390 400 410 420
pF1KE2 SAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTLRALCGR
.:.::..: : :::: :.:.:: ...::..: : :.::.. ::.:: : . ::.::..
CCDS10 TALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQS-ILAKLPPK-GKLRSLCSQ
430 440 450 460 470
430 440 450 460
pF1KE2 HTEKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG
:.:.:. :. ..: .:. :::::::::..: :
CCDS10 HVERLQIFQHLHPIVVQAAFPPLYKELFSTETESPVGLSK
480 490 500 510
>>CCDS11361.1 NR1D1 gene_id:9572|Hs108|chr17 (614 aa)
initn: 650 init1: 265 opt: 438 Z-score: 442.1 bits: 91.5 E(32554): 2.7e-18
Smith-Waterman score: 762; 33.0% identity (61.1% similar) in 491 aa overlap (15-437:129-610)
10 20 30 40
pF1KE2 MMYFVIAAMKAQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRR
.. ::.::: .::.:::: .::::::::::
CCDS11 PPGSLQVAMEDSSRVSPSKSTSNITKLNGMVLLCKVCGDVASGFHYGVHACEGCKGFFRR
100 110 120 130 140 150
50 60 70 80 90 100
pF1KE2 SQQSNATYS-CPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYA
: :.: :. : ...:: : : .:::::.::..:::.::::::::.:::. :.... . :
CCDS11 SIQQNIQYKRCLKNENCSIVRINRNRCQQCRFKKCLSVGMSRDAVRFGRIPKREKQRMLA
160 170 180 190 200 210
110 120 130
pF1KE2 EVQK-HRMQQQQRDHQ--------QQP-----GEAEP-----------------LTPTYN
:.:. . ..: . : :.: : . : ::: .
CCDS11 EMQSAMNLANNQLSSQCPLETSPTQHPTPGPMGPSPPPAPVPSPLVGFSQFPQQLTPPRS
220 230 240 250 260 270
140 150 160 170
pF1KE2 ISANGLTE--------LHDDLSNYID---GHTPEGSKADSAVSS------FYLDIQ---P
: . .: : .. .: : .: . .:. : .: . : :
CCDS11 PSPEPTVEDVISQVARAHREIFTYAHDKLGSSPGNFNANHASGSPPATTPHRWENQGCPP
280 290 300 310 320 330
180 190 200 210
pF1KE2 SPDQSGL--------DINGIKPEPICDYTPASGFFPY---C--SFTNGET-SPTVSMAEL
.:.... .::.. : .: :. : : : .::. :: .:
CCDS11 APNDNNTLAAQRHNEALNGLRQAP-SSYPPTWPPGPAHHSCHQSNSNGHRLCPTHVYAAP
340 350 360 370 380 390
220 230 240 250 260 270
pF1KE2 EHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQY
: : : . .. ... .. .. ... . .:. ....: :..
CCDS11 EGKAPANSPRQGNS--------KNVLLACPMNMYPHGRSGRTVQEIWEDFSMSFTPAVRE
400 410 420 430 440
280 290 300 310 320 330
pF1KE2 VVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYA-SPDVFK
::::::.: :: .: :.::..:::::..::...:. :. ...::.: .. . : . .
CCDS11 VVEFAKHIPGFRDLSQHDQVTLLKAGTFEVLMVRFASLFNVKDQTVMFLSRTTYSLQELG
450 460 470 480 490 500
340 350 360 370 380 390
pF1KE2 SLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLA
..: :..: .:.:...: :. :::.:..::.: ::.::::: .......:.::. . :
CCDS11 AMGMGDLLSAMFDFSEKLNSLALTEEELGLFTAVVLVSADRSGMENSASVEQLQETLLRA
510 520 530 540 550 560
400 410 420 430 440 450
pF1KE2 LQHVLQKNHR-EDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELF
:. .. ::. : . .:::. :. ::.: . :.:::..:.
CCDS11 LRALVLKNRPLETSRFTKLLLKLPDLRTLNNMHSEKLLSFRVDAQ
570 580 590 600 610
460
pF1KE2 TSEFEPAMQIDG
>>CCDS33718.1 NR1D2 gene_id:9975|Hs108|chr3 (579 aa)
initn: 544 init1: 248 opt: 428 Z-score: 432.5 bits: 89.7 E(32554): 9.1e-18
Smith-Waterman score: 823; 34.0% identity (63.2% similar) in 486 aa overlap (15-441:100-579)
10 20 30 40
pF1KE2 MMYFVIAAMKAQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRR
.. ::.::: .::.:::: .::::::::::
CCDS33 DRIDCSMKTSKSSAPGMTKSHSGVTKFSGMVLLCKVCGDVASGFHYGVHACEGCKGFFRR
70 80 90 100 110 120
50 60 70 80 90 100
pF1KE2 SQQSNATYS-CPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYA
: :.: :. : ...:: : : .:::::.::..:::.::::::::.:::. :.... .
CCDS33 SIQQNIQYKKCLKNENCSIMRMNRNRCQQCRFKKCLSVGMSRDAVRFGRIPKREKQRMLI
130 140 150 160 170 180
110 120 130
pF1KE2 EVQ---KHRMQQQ-----QRD----HQQQ---PGEAE----PLTPTYNISANG-------
:.: : :..: : : :..: :.. . : ::....
CCDS33 EMQSAMKTMMNSQFSGHLQNDTLVEHHEQTALPAQEQLRPKPQLEQENIKSSSPPSSDFA
190 200 210 220 230 240
140 150 160 170
pF1KE2 -------LTELHDDL--------SNYIDGHTPE-GSKADSAVSSFYLDIQPSPD------
.:. : : : .. :. : . . . .. :. . .
CCDS33 KEEVIGMVTRAHKDTFMYNQEQQENSAESMQPQRGERIPKNMEQYNLNHDHCGNGLSSHF
250 260 270 280 290 300
180 190 200 210 220
pF1KE2 ---QSGLDING-IKPEPICDYTPASGFF---PYC-SFTNGETSPTVSMAELEHLAQNISK
.: .:: .: . : : . .. .: .:.:. :. . . . .. ..:: .:
CCDS33 PCSESQQHLNGQFKGRNIMHYPNGHAICIANGHCMNFSNAYTQRVCDRVPIDGFSQNENK
310 320 330 340 350 360
230 240 250 260 270 280
pF1KE2 SHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRID
. .:: . .. ... .:. . .:. ....: :.. ::::::::
CCDS33 N-----SYLCNTGGRMHLVCPMSKSPYVDPHKSGHEIWEEFSMSFTPAVKEVVEFAKRIP
370 380 390 400 410 420
290 300 310 320 330 340
pF1KE2 GFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYF-DGKYASPDVFKSLGCEDFIS
:: .: :.::. :::::..::...:. ::... :: : .:: : : ..:.: :...
CCDS33 GFRDLSQHDQVNLLKAGTFEVLMVRFASLFDAKERTVTFLSGKKYSVDDLHSMGAGDLLN
430 440 450 460 470 480
350 360 370 380 390 400
pF1KE2 FVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNH
.:::...: ...:...:..::.: ::.::::: ... ..: ::. . ::. ...:::
CCDS33 SMFEFSEKLNALQLSDEEMSLFTAVVLVSADRSGIENVNSVEALQETLIRALRTLIMKNH
490 500 510 520 530 540
410 420 430 440 450 460
pF1KE2 -REDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQ
: .:.:::. :. ::.: . :.:.:.::: ..:
CCDS33 PNEASIFTKLLLKLPDLRSLNNMHSEELLAFK-VHP
550 560 570
pF1KE2 IDG
>>CCDS6856.1 NR5A1 gene_id:2516|Hs108|chr9 (461 aa)
initn: 382 init1: 352 opt: 419 Z-score: 425.0 bits: 87.9 E(32554): 2.4e-17
Smith-Waterman score: 440; 26.8% identity (53.8% similar) in 444 aa overlap (18-433:13-437)
10 20 30 40 50 60
pF1KE2 MMYFVIAAMKAQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNC
: .:::: :: :::..:::.:::::.:. :.: :.: ....:
CCDS68 MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSC
10 20 30 40 50
70 80 90 100 110 120
pF1KE2 LIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQ
::.:.:.:: ::.::::.::: .::. :: . :... .. : .::. : .
CCDS68 KIDKTQRKRCPFCRFQKCLTVGMRLEAVRADRM-RGGRNKFGPMYKRDRALKQQKKAQIR
60 70 80 90 100 110
130 140 150 160 170
pF1KE2 ---------PGEAEPLTPTYNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQ
: . : : . :: . . . : : .: .. .. . .
CCDS68 ANGFKLETGPPMGVPPPPPPAPDYVLPPSLHGPEPKGLAAGPPAGPLGDFGAPALPMAVP
120 130 140 150 160 170
180 190 200 210 220
pF1KE2 PS---------PDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLA
. : : :.. ::: .: . .:: : : . .
CCDS68 GAHGPLAGYLYPAFPGRAIKSEYPEPYA--SPPQPGLPY-----GYPEPFSG-------G
180 190 200 210 220
230 240 250 260 270 280
pF1KE2 QNISKSHLETCQYLREELQQITWQTF--LQEEIENYQNKQREVMWQLCAIKITEAIQYVV
:. . :. : :. . .:. . . ::: .. . : .. :: . :. .:
CCDS68 PNVPELILQLLQ-LEPDEDQVRARILGCLQEPTKSRPD-QPAAFGLLCRMADQTFIS-IV
230 240 250 260 270
290 300 310 320 330
pF1KE2 EFAKRIDGFMELCQNDQIVLLKAGSLEV-VFIRMCRAFD--SQNNTVYFDGKYASPDVFK
..:.: : :: ::..::. :. :: .. : . .... . :. . .
CCDS68 DWARRCMVFKELEVADQMTLLQNCWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVA
280 290 300 310 320 330
340 350 360 370 380 390
pF1KE2 SLGCEDFISFVF---EFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKI
. . . :.:. :. .: ...: ..:.. .. ..:.: : ..:.... .. :.:
CCDS68 TQAGSLLHSLVLRAQELVLQLLALQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKA
340 350 360 370 380 390
400 410 420 430 440 450
pF1KE2 QLAL-QHVL-QKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLY
. :: ...: . : : . :.: : .::: . : :
CCDS68 NAALLDYTLCHYPHCGDKFQQLLLCLVE-VRALSMQAKEYLYHKHLGNEMPRNNLLIEML
400 410 420 430 440 450
460
pF1KE2 KELFTSEFEPAMQIDG
CCDS68 QAKQT
460
468 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 20:45:24 2016 done: Mon Nov 7 20:45:24 2016
Total Scan time: 2.340 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]