Result of FASTA (ccds) for
pFN21AE2471
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2471, 597 aa
1>>>pF1KE2471 597 - 597 aa - 597 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.0401+/-0.00101; mu= 7.7742+/- 0.061
mean_var=195.9202+/-39.037, 0's: 0 Z-trim(111.3): 59 B-trim: 264 in 1/51
Lambda= 0.091629
statistics sampled from 12254 (12309) to 12254 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.72), E-opt: 0.2 (0.378), width: 16
Scan time: 3.430
The best scores are: opt bits E(32554)
CCDS34127.2 BRD9 gene_id:65980|Hs108|chr5 ( 597) 3944 534.2 1.8e-151
CCDS34128.2 BRD9 gene_id:65980|Hs108|chr5 ( 544) 2921 399.0 8.4e-111
CCDS10742.1 BRD7 gene_id:29117|Hs108|chr16 ( 651) 875 128.6 2.5e-29
CCDS54007.1 BRD7 gene_id:29117|Hs108|chr16 ( 652) 875 128.6 2.5e-29
>>CCDS34127.2 BRD9 gene_id:65980|Hs108|chr5 (597 aa)
initn: 3944 init1: 3944 opt: 3944 Z-score: 2833.0 bits: 534.2 E(32554): 1.8e-151
Smith-Waterman score: 3944; 100.0% identity (100.0% similar) in 597 aa overlap (1-597:1-597)
10 20 30 40 50 60
pF1KE2 MGKKHKKHKAEWRSSYEDYADKPLEKPLKLVLKVGGSEVTELSGSGHDSSYYDDRSDHER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 MGKKHKKHKAEWRSSYEDYADKPLEKPLKLVLKVGGSEVTELSGSGHDSSYYDDRSDHER
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 ERHKEKKKKKKKKSEKEKHLDDEERRKRKEEKKRKREREHCDTEGEADDFDPGKKVEVEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 ERHKEKKKKKKKKSEKEKHLDDEERRKRKEEKKRKREREHCDTEGEADDFDPGKKVEVEP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 PPDRPVRACRTQPAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 PPDRPVRACRTQPAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 MDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMSKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 MDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMSKQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 AALLGNEDTAVEEPVPEVVPVQVETAKKSKKPSREVISCMFEPEGNACSLTDSTAEEHVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 AALLGNEDTAVEEPVPEVVPVQVETAKKSKKPSREVISCMFEPEGNACSLTDSTAEEHVL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 ALVEHAADEARDRINRFLPGGKMGYLKRNGDGSLLYSVVNTAEPDADEEETHPVDLSSLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 ALVEHAADEARDRINRFLPGGKMGYLKRNGDGSLLYSVVNTAEPDADEEETHPVDLSSLS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 SKLLPGFTTLGFKDERRNKVTFLSSATTALSMQNNSVFGDLKSDEMELLYSAYGDETGVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 SKLLPGFTTLGFKDERRNKVTFLSSATTALSMQNNSVFGDLKSDEMELLYSAYGDETGVQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 CALSLQEFVKDAGSYSKKVVDDLLDQITGGDHSRTLFQLKQRRNVPMKPPDEAKVGDTLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 CALSLQEFVKDAGSYSKKVVDDLLDQITGGDHSRTLFQLKQRRNVPMKPPDEAKVGDTLG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 DSSSSVLEFMSMKSYPDVSVDISMLSSLGKVKKELDPDDSHLNLDETTKLLQDLHEAQAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 DSSSSVLEFMSMKSYPDVSVDISMLSSLGKVKKELDPDDSHLNLDETTKLLQDLHEAQAE
490 500 510 520 530 540
550 560 570 580 590
pF1KE2 RGGSRPSSNLSSLSNASERDQHHLGSPSRLSVGEQPDVTHDPYEFLQSPEPAASAKT
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 RGGSRPSSNLSSLSNASERDQHHLGSPSRLSVGEQPDVTHDPYEFLQSPEPAASAKT
550 560 570 580 590
>>CCDS34128.2 BRD9 gene_id:65980|Hs108|chr5 (544 aa)
initn: 2923 init1: 2888 opt: 2921 Z-score: 2102.7 bits: 399.0 E(32554): 8.4e-111
Smith-Waterman score: 2921; 85.1% identity (90.6% similar) in 544 aa overlap (61-597:9-544)
40 50 60 70 80 90
pF1KE2 VLKVGGSEVTELSGSGHDSSYYDDRSDHERERHKEKKKKKKKKSEKEKHLDDEERRKRKE
:: .:.:.....: ... . ::.
CCDS34 MMTGQTMSERGTKKRKRRRRRSPRRRSI--WTMRKEGS
10 20 30
100 110 120 130 140
pF1KE2 EKKRKREREHCDTEGEADDFDP---GKKVE-VEPPPDRPVRACRTQP---AENESTPIQQ
:.::. :. .: . . . :.. . .: . :: ..:: :. :. .
CCDS34 ERKRRSGSERGSTVTRRERLTTLILGRRWRWSRPQIGQSERAGHSQPKMRAHLFSNSWNT
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE2 LLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKA
: .::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 SSASF------RDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKA
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE2 DFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMSKQAALLGNEDTAVEEPVPEVVPVQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 DFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMSKQAALLGNEDTAVEEPVPEVVPVQV
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE2 ETAKKSKKPSREVISCMFEPEGNACSLTDSTAEEHVLALVEHAADEARDRINRFLPGGKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 ETAKKSKKPSREVISCMFEPEGNACSLTDSTAEEHVLALVEHAADEARDRINRFLPGGKM
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE2 GYLKRNGDGSLLYSVVNTAEPDADEEETHPVDLSSLSSKLLPGFTTLGFKDERRNKVTFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 GYLKRNGDGSLLYSVVNTAEPDADEEETHPVDLSSLSSKLLPGFTTLGFKDERRNKVTFL
280 290 300 310 320 330
390 400 410 420 430 440
pF1KE2 SSATTALSMQNNSVFGDLKSDEMELLYSAYGDETGVQCALSLQEFVKDAGSYSKKVVDDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 SSATTALSMQNNSVFGDLKSDEMELLYSAYGDETGVQCALSLQEFVKDAGSYSKKVVDDL
340 350 360 370 380 390
450 460 470 480 490 500
pF1KE2 LDQITGGDHSRTLFQLKQRRNVPMKPPDEAKVGDTLGDSSSSVLEFMSMKSYPDVSVDIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 LDQITGGDHSRTLFQLKQRRNVPMKPPDEAKVGDTLGDSSSSVLEFMSMKSYPDVSVDIS
400 410 420 430 440 450
510 520 530 540 550 560
pF1KE2 MLSSLGKVKKELDPDDSHLNLDETTKLLQDLHEAQAERGGSRPSSNLSSLSNASERDQHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 MLSSLGKVKKELDPDDSHLNLDETTKLLQDLHEAQAERGGSRPSSNLSSLSNASERDQHH
460 470 480 490 500 510
570 580 590
pF1KE2 LGSPSRLSVGEQPDVTHDPYEFLQSPEPAASAKT
::::::::::::::::::::::::::::::::::
CCDS34 LGSPSRLSVGEQPDVTHDPYEFLQSPEPAASAKT
520 530 540
>>CCDS10742.1 BRD7 gene_id:29117|Hs108|chr16 (651 aa)
initn: 1033 init1: 715 opt: 875 Z-score: 639.9 bits: 128.6 E(32554): 2.5e-29
Smith-Waterman score: 1174; 36.3% identity (68.0% similar) in 597 aa overlap (1-562:1-584)
10 20 30 40 50
pF1KE2 MGKKHKKHKAEWRSSYEDYADKPLEKPLKLVLKVGGSEVTELS--GSGHDSSYYDDRSDH
:::::::::.. . ::.: .::::::::::::.:::::: .:::::: ..:..::
CCDS10 MGKKHKKHKSD-KHLYEEY----VEKPLKLVLKVGGNEVTELSTGSSGHDSSLFEDKNDH
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 ERERHKEKKKKKKKKSEKEKHLDDEERRKRK-EEKKRKREREHCDTEGEADDFDPGKKVE
. .::..:.::.::.::. ... :..:. .: :.::.:.. ..:.: : .. :.
CCDS10 D--KHKDRKRKKRKKGEKQIPGEEKGRKRRRVKEDKKKRDRDRVENEAEKD-LQCHAPVR
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE2 VEPPPDRPVRACRTQPAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMII
.. ::..:. . .. : :.::.:. :....:::::::: .::.::::: :::::::::
CCDS10 LDLPPEKPLTSSLAKQEEVEQTPLQEALNQLMRQLQRKDPSAFFSFPVTDFIAPGYSMII
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE2 KHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMM
::::::.:::.:: :.:.:. :.: .::::: ::: ::.:.:.::: :::.::.:.:..
CCDS10 KHPMDFSTMKEKIKNNDYQSIEELKDNFKLMCTNAMIYNKPETIYYKAAKKLLHSGMKIL
180 190 200 210 220 230
240 250 260 270 280
pF1KE2 SKQ--AALLGNEDTAVEEPVPEVVPVQVETAK---------KSKKPSREVISCMFEPEGN
:.. .: . : .. . ..:.. . .. : .. . :. ..
CCDS10 SQERIQSLKQSIDFMADLQKTRKQKDGTDTSQSGEDGGCWQREREDSGDAEAHAFKSPSK
240 250 260 270 280 290
290 300 310 320 330
pF1KE2 ACSLTD---------STAEEHVLALVEHAADEARDRINRFLPGGKMGYLKRNGDGSLLYS
. : :. :. ... . :. ...: : ... . .:. ::. .
CCDS10 ENKKKDKDMLEDKFKSNNLEREQEQLDRIVKESGGKLTRRLVNSQCEFERRKPDGTTTLG
300 310 320 330 340 350
340 350 360 370 380 390
pF1KE2 VVNTAEPDADEEETHPVDLSSLSSKLLPGFTTL-GFKDERRNKVT---FLSSAT-TALSM
... ..: . : :: :. ...: : .:: :::...::::: .:. . .. .
CCDS10 LLHPVDPIVGEPGYCPVRLGMTTGRLQSGVNTLQGFKEDKRNKVTPVLYLNYGPYSSYAP
360 370 380 390 400 410
400 410 420 430 440 450
pF1KE2 QNNSVFGDLKSDEMELLYSAYGDETGVQCALSLQEFVKDAGSYSKKVVDDLLDQITGGDH
. .:.:.....:. .:.::.::... . .:..::. .: ..:.::: .: : :
CCDS10 HYDSTFANISKDDSDLIYSTYGEDSDLPSDFSIHEFLATCQDYPYVMADSLLDVLTKGGH
420 430 440 450 460 470
460 470 480 490 500
pF1KE2 SRTLFQLKQRRNVPMKPPDEA--KVGDTLGDSSSSVLEFMSM--KSYPDVSVDISMLSSL
:::: :. .. . : ::. .. :: . . .: . .: : . .. ....
CCDS10 SRTL----QEMEMSL-PEDEGHTRTLDTAKEMEITEVEPPGRLDSSTQDRLIALKAVTNF
480 490 500 510 520
510 520 530 540 550 560
pF1KE2 GKVKKELDPDDSHL---NLDETTKLLQDLHEAQAERGGSRPSSNLSSLSNASERDQHHLG
: . .: ..... .:::::.::..:.::: :: ..:: :. : . : :..:
CCDS10 GVPVEVFDSEEAEIFQKKLDETTRLLRELQEAQNERLSTRPPPNMICLLGPSYREMHLAE
530 540 550 560 570 580
570 580 590
pF1KE2 SPSRLSVGEQPDVTHDPYEFLQSPEPAASAKT
CCDS10 QVTNNLKELAQQVTPGDIVSTYGVRKAMGISIPSPVMENNFVDLTEDTEEPKKTDVAECG
590 600 610 620 630 640
>>CCDS54007.1 BRD7 gene_id:29117|Hs108|chr16 (652 aa)
initn: 1033 init1: 715 opt: 875 Z-score: 639.9 bits: 128.6 E(32554): 2.5e-29
Smith-Waterman score: 1171; 36.2% identity (68.2% similar) in 600 aa overlap (1-562:1-585)
10 20 30 40 50
pF1KE2 MGKKHKKHKAEWRSSYEDYADKPLEKPLKLVLKVGGSEVTELS--GSGHDSSYYDDRSDH
:::::::::.. . ::.: .::::::::::::.:::::: .:::::: ..:..::
CCDS54 MGKKHKKHKSD-KHLYEEY----VEKPLKLVLKVGGNEVTELSTGSSGHDSSLFEDKNDH
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 ERERHKEKKKKKKKKSEKEKHLDDEERRKRK-EEKKRKREREHCDTEGEADDFDPGKKVE
. .::..:.::.::.::. ... :..:. .: :.::.:.. ..:.: : .. :.
CCDS54 D--KHKDRKRKKRKKGEKQIPGEEKGRKRRRVKEDKKKRDRDRVENEAEKD-LQCHAPVR
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE2 VEPPPDRPVRACRTQPAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMII
.. ::..:. . .. : :.::.:. :....:::::::: .::.::::: :::::::::
CCDS54 LDLPPEKPLTSSLAKQEEVEQTPLQEALNQLMRQLQRKDPSAFFSFPVTDFIAPGYSMII
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE2 KHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMM
::::::.:::.:: :.:.:. :.: .::::: ::: ::.:.:.::: :::.::.:.:..
CCDS54 KHPMDFSTMKEKIKNNDYQSIEELKDNFKLMCTNAMIYNKPETIYYKAAKKLLHSGMKIL
180 190 200 210 220 230
240 250 260 270 280
pF1KE2 SKQ--AALLGNEDTAVEEPVPEVVPVQVETAK---------KSKKPSREVISCMFEPEGN
:.. .: . : .. . ..:.. . .. : .. . :. ..
CCDS54 SQERIQSLKQSIDFMADLQKTRKQKDGTDTSQSGEDGGCWQREREDSGDAEAHAFKSPSK
240 250 260 270 280 290
290 300 310 320 330
pF1KE2 ACSLTD---------STAEEHVLALVEHAADEARDRINRFLPGGKMGYLKRNGDGSLLYS
. : :. :. ... . :. ...: : ... . .:. ::. .
CCDS54 ENKKKDKDMLEDKFKSNNLEREQEQLDRIVKESGGKLTRRLVNSQCEFERRKPDGTTTLG
300 310 320 330 340 350
340 350 360 370 380 390
pF1KE2 VVNTAEPDADEEETHPVDLSSLSSKLLPGFTTL-GFKDERRNKVT---FLSSAT-TALSM
... ..: . : :: :. ...: : .:: :::...::::: .:. . .. .
CCDS54 LLHPVDPIVGEPGYCPVRLGMTTGRLQSGVNTLQGFKEDKRNKVTPVLYLNYGPYSSYAP
360 370 380 390 400 410
400 410 420 430 440 450
pF1KE2 QNNSVFGDLKSDEMELLYSAYGDETGVQCALSLQEFVKDAGSYSKKVVDDLLDQITGGDH
. .:.:.....:. .:.::.::... . .:..::. .: ..:.::: .: : :
CCDS54 HYDSTFANISKDDSDLIYSTYGEDSDLPSDFSIHEFLATCQDYPYVMADSLLDVLTKGGH
420 430 440 450 460 470
460 470 480 490 500
pF1KE2 SRTLFQLKQRRNVPMKPPDEAKVGDTLGDSSSSVLEFMSMK-------SYPDVSVDISML
:::: :. .. . : ::... :: :... . .. .. : : . .. .
CCDS54 SRTL----QEMEMSL-PEDEGHT-RTL-DTAKEMEQITEVEPPGRLDSSTQDRLIALKAV
480 490 500 510 520
510 520 530 540 550 560
pF1KE2 SSLGKVKKELDPDDSHL---NLDETTKLLQDLHEAQAERGGSRPSSNLSSLSNASERDQH
...: . .: ..... .:::::.::..:.::: :: ..:: :. : . : :..:
CCDS54 TNFGVPVEVFDSEEAEIFQKKLDETTRLLRELQEAQNERLSTRPPPNMICLLGPSYREMH
530 540 550 560 570 580
570 580 590
pF1KE2 HLGSPSRLSVGEQPDVTHDPYEFLQSPEPAASAKT
CCDS54 LAEQVTNNLKELAQQVTPGDIVSTYGVRKAMGISIPSPVMENNFVDLTEDTEEPKKTDVA
590 600 610 620 630 640
597 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 20:30:24 2016 done: Mon Nov 7 20:30:25 2016
Total Scan time: 3.430 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]