FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE2458, 276 aa
  1>>>pF1KE2458 276 - 276 aa - 276 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.8748+/-0.00114; mu= 12.1565+/- 0.069
 mean_var=83.3755+/-16.289, 0's: 0 Z-trim(103.7): 56  B-trim: 76 in 2/49
 Lambda= 0.140461
 statistics sampled from 7508 (7540) to 7508 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.598), E-opt: 0.2 (0.232), width:  16
 Scan time:  1.920

The best scores are:                                      opt bits E(32554)
CCDS4561.1 SCGN gene_id:10590|Hs108|chr6           ( 276) 1827 380.2 8.6e-106
CCDS10899.1 CALB2 gene_id:794|Hs108|chr16          ( 271)  611 133.8 1.3e-31
CCDS6251.1 CALB1 gene_id:793|Hs108|chr8            ( 261)  561 123.7 1.4e-28


>>CCDS4561.1 SCGN gene_id:10590|Hs108|chr6                (276 aa)
 initn: 1827 init1: 1827 opt: 1827  Z-score: 2012.8  bits: 380.2 E(32554): 8.6e-106
Smith-Waterman score: 1827; 100.0% identity (100.0% similar) in 276 aa overlap (1-276:1-276)

               10        20        30        40        50        60
pF1KE2 MDSSREPTLGRLDAAGFWQVWQRFDADEKGYIEEKELDAFFLHMLMKLGTDDTVMKANLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 MDSSREPTLGRLDAAGFWQVWQRFDADEKGYIEEKELDAFFLHMLMKLGTDDTVMKANLH
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 KVKQQFMTTQDASKDGRIRMKELAGMFLSEDENFLLLFRRENPLDSSVEFMQIWRKYDAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 KVKQQFMTTQDASKDGRIRMKELAGMFLSEDENFLLLFRRENPLDSSVEFMQIWRKYDAD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 SSGFISAAELRNFLRDLFLHHKKAISEAKLEEYTGTMMKIFDRNKDGRLDLNDLARILAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 SSGFISAAELRNFLRDLFLHHKKAISEAKLEEYTGTMMKIFDRNKDGRLDLNDLARILAL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 QENFLLQFKMDACSTEERKRDFEKIFAYYDVSKTGALEGPEVDGFVKDMMELVQPSISGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 QENFLLQFKMDACSTEERKRDFEKIFAYYDVSKTGALEGPEVDGFVKDMMELVQPSISGV
              190       200       210       220       230       240

              250       260       270      
pF1KE2 DLDKFREILLRHCDVNKDGKIQKSELALCLGLKINP
       ::::::::::::::::::::::::::::::::::::
CCDS45 DLDKFREILLRHCDVNKDGKIQKSELALCLGLKINP
              250       260       270      

>>CCDS10899.1 CALB2 gene_id:794|Hs108|chr16               (271 aa)
 initn: 343 init1: 317 opt: 611  Z-score: 681.2  bits: 133.8 E(32554): 1.3e-31
Smith-Waterman score: 611; 38.4% identity (71.1% similar) in 263 aa overlap (9-270:13-265)

                   10        20        30        40         50     
pF1KE2     MDSSREPTLGRLDAAGFWQVWQRFDADEKGYIEEKELDAFFLHML-MKLGTDDTVM
                   :..: :. : ..:..:::: .:::: :::. :: ..   . :.     
CCDS10 MAGPQQQPPYLHLAELTASQFLEIWKHFDADGNGYIEGKELENFFQELEKARKGSGMMSK
               10        20        30        40        50        60

          60        70        80        90       100       110     
pF1KE2 KANLHKVKQQFMTTQDASKDGRIRMKELAGMFLSEDENFLLLFRRENPLDSSVEFMQIWR
       . :. .  ..::   : ..::.:.: ::: ..:  .::::: ::..  . ::.:::. ::
CCDS10 SDNFGEKMKEFMQKYDKNSDGKIEMAELA-QILPTEENFLLCFRQH--VGSSAEFMEAWR
               70        80         90       100         110       

         120       130       140       150       160       170     
pF1KE2 KYDADSSGFISAAELRNFLRDLFLHHKKAISEAKLEEYTGTMMKIFDRNKDGRLDLNDLA
       :::.: ::.: : ::..:: ::. . ..  .: ::.::: :....:: : ::.: :....
CCDS10 KYDTDRSGYIEANELKGFLSDLLKKANRPYDEPKLQEYTQTILRMFDLNGDGKLGLSEMS
       120       130       140       150       160       170       

         180       190       200       210       220       230     
pF1KE2 RILALQENFLLQFKMDACSTEERKRDFEKIFAYYDVSKTGALEGPEVDGFVKDMMELVQP
       :.: .::::::.:.    ..::    :. ::..:: ...: ..  :.:...::..:  . 
CCDS10 RLLPVQENFLLKFQGMKLTSEE----FNAIFTFYDKDRSGYIDEHELDALLKDLYEKNKK
       180       190           200       210       220       230   

         240       250       260       270      
pF1KE2 SISGVDLDKFREILLRHCDVNKDGKIQKSELALCLGLKINP
        ..  .: ..:. ..   .. . ::. ...: . :      
CCDS10 EMNIQQLTNYRKSVM---SLAEAGKLYRKDLEIVLCSEPPM
           240          250       260       270 

>>CCDS6251.1 CALB1 gene_id:793|Hs108|chr8                 (261 aa)
 initn: 352 init1: 352 opt: 561  Z-score: 626.7  bits: 123.7 E(32554): 1.4e-28
Smith-Waterman score: 561; 37.6% identity (66.2% similar) in 263 aa overlap (12-271:11-259)

               10        20        30        40        50        60
pF1KE2 MDSSREPTLGRLDAAGFWQVWQRFDADEKGYIEEKELDAFFLHMLMKLGTDDTVMKANLH
                  . :. :...: .:::: .::.: :::.    .....:         .: 
CCDS62  MAESHLQSSLITASQFFEIWLHFDADGSGYLEGKELQ----NLIQELQQARKKAGLELS
                10        20        30            40        50     

               70        80        90       100       110       120
pF1KE2 KVKQQFMTTQDASKDGRIRMKELAGMFLSEDENFLLLFRRENPLDSSVEFMQIWRKYDAD
          . :.       ::.: . ::: . :  .:::::::: .. : :  :::. :::::.:
CCDS62 PEMKTFVDQYGQRDDGKIGIVELAHV-LPTEENFLLLFRCQQ-LKSCEEFMKTWRKYDTD
          60        70        80         90        100       110   

              130       140       150       160       170       180
pF1KE2 SSGFISAAELRNFLRDLFLHHKKAISEAKLEEYTGTMMKIFDRNKDGRLDLNDLARILAL
        :::: . ::.:::.::. . .:.....:: :::  :.:.:: :.::.:.:...::.: .
CCDS62 HSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPV
           120       130       140       150       160       170   

               190       200       210       220       230         
pF1KE2 QENFLLQFK-MDACSTEERKRDFEKIFAYYDVSKTGALEGPEVDGFVKDMMELVQPSISG
       ::::::.:. .  :. :     :.: :  :: . .: ..  :.:...::. :  . ... 
CCDS62 QENFLLKFQGIKMCGKE-----FNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDI
           180       190            200       210       220        

     240       250       260         270      
pF1KE2 VDLDKFREILLRHCDVNKDGKIQKSELAL--CLGLKINP
        ..  ... ..   :    ::. ...:::  : :     
CCDS62 NNITTYKKNIMALSD---GGKLYRTDLALILCAGDN   
      230       240          250       260    




276 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Mon Nov  7 20:12:39 2016 done: Mon Nov  7 20:12:40 2016
 Total Scan time:  1.920 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]