Result of FASTA (ccds) for
pFN21AE2451
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2451, 378 aa
1>>>pF1KE2451 378 - 378 aa - 378 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.8532+/-0.000977; mu= 4.5273+/- 0.059
mean_var=126.6896+/-25.024, 0's: 0 Z-trim(108.7): 54 B-trim: 30 in 2/49
Lambda= 0.113947
statistics sampled from 10324 (10360) to 10324 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.682), E-opt: 0.2 (0.318), width: 16
Scan time: 2.990
The best scores are: opt bits E(32554)
CCDS4332.1 TIMD4 gene_id:91937|Hs108|chr5 ( 378) 2485 419.7 2.1e-117
CCDS54943.1 TIMD4 gene_id:91937|Hs108|chr5 ( 350) 1660 284.1 1.3e-76
CCDS43392.1 HAVCR1 gene_id:26762|Hs108|chr5 ( 364) 449 85.0 1.2e-16
CCDS78076.1 HAVCR1 gene_id:26762|Hs108|chr5 ( 401) 449 85.0 1.3e-16
CCDS4333.1 HAVCR2 gene_id:84868|Hs108|chr5 ( 301) 333 65.9 5.3e-11
>>CCDS4332.1 TIMD4 gene_id:91937|Hs108|chr5 (378 aa)
initn: 2485 init1: 2485 opt: 2485 Z-score: 2221.3 bits: 419.7 E(32554): 2.1e-117
Smith-Waterman score: 2485; 99.7% identity (100.0% similar) in 378 aa overlap (1-378:1-378)
10 20 30 40 50 60
pF1KE2 MSKEPLILWLMIEFWWLYLTPVTSETVVTEVLGHRVTLPCLYSSWSHNSNSMCWGKDQCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 MSKEPLILWLMIEFWWLYLTPVTSETVVTEVLGHRVTLPCLYSSWSHNSNSMCWGKDQCP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 YSGCKEALIRTDGMRVTSRKSAKYRLQGTIPRGDVSLTILNPSESDSGVYCCRIEVPGWF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 YSGCKEALIRTDGMRVTSRKSAKYRLQGTIPRGDVSLTILNPSESDSGVYCCRIEVPGWF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 NDVKINVRLNLQRASTTTHRTATTTTRRTTTTSPTTTRQMTTTPAALPTTVVTTPDLTTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 NDVKINVRLNLQRASTTTHRTATTTTRRTTTTSPTTTRQMTTTPAALPTTVVTTPDLTTG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 TPLQMTTIAVFTTANTCLSLTPSTLPEEATGLLTPEPSKEGPILTAESETVLPSDSWSSA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
CCDS43 TPLQMTTIAVFTTANTCLSLTPSTLPEEATGLLTPEPSKEGPILTAESETVLPSDSWSSV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 ESTSADTVLLTSKESKVWDLPSTSHVSMWKTSDSVSSPQPGASDTAVPEQNKTTKTGQMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 ESTSADTVLLTSKESKVWDLPSTSHVSMWKTSDSVSSPQPGASDTAVPEQNKTTKTGQMD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 GIPMSMKNEMPISQLLMIIAPSLGFVLFALFVAFLLRGKLMETYCSQKHTRLDYIGDSKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 GIPMSMKNEMPISQLLMIIAPSLGFVLFALFVAFLLRGKLMETYCSQKHTRLDYIGDSKN
310 320 330 340 350 360
370
pF1KE2 VLNDVQHGREDEDGLFTL
::::::::::::::::::
CCDS43 VLNDVQHGREDEDGLFTL
370
>>CCDS54943.1 TIMD4 gene_id:91937|Hs108|chr5 (350 aa)
initn: 1727 init1: 1660 opt: 1660 Z-score: 1488.8 bits: 284.1 E(32554): 1.3e-76
Smith-Waterman score: 2223; 92.3% identity (92.6% similar) in 378 aa overlap (1-378:1-350)
10 20 30 40 50 60
pF1KE2 MSKEPLILWLMIEFWWLYLTPVTSETVVTEVLGHRVTLPCLYSSWSHNSNSMCWGKDQCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 MSKEPLILWLMIEFWWLYLTPVTSETVVTEVLGHRVTLPCLYSSWSHNSNSMCWGKDQCP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 YSGCKEALIRTDGMRVTSRKSAKYRLQGTIPRGDVSLTILNPSESDSGVYCCRIEVPGWF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 YSGCKEALIRTDGMRVTSRKSAKYRLQGTIPRGDVSLTILNPSESDSGVYCCRIEVPGWF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 NDVKINVRLNLQRASTTTHRTATTTTRRTTTTSPTTTRQMTTTPAALPTTVVTTPDLTTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 NDVKINVRLNLQRASTTTHRTATTTTRRTTTTSPTTTRQMTTTPAALPTTVVTTPDLTTG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 TPLQMTTIAVFTTANTCLSLTPSTLPEEATGLLTPEPSKEGPILTAESETVLPSDSWSSA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
CCDS54 TPLQMTTIAVFTTANTCLSLTPSTLPEEATGLLTPEPSKEGPILTAESETVLPSDSWSSV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 ESTSADTVLLTSKESKVWDLPSTSHVSMWKTSDSVSSPQPGASDTAVPEQNKTTKTGQMD
::::::::::::: :::::::::::::::::::
CCDS54 ESTSADTVLLTSK----------------------------ASDTAVPEQNKTTKTGQMD
250 260 270
310 320 330 340 350 360
pF1KE2 GIPMSMKNEMPISQLLMIIAPSLGFVLFALFVAFLLRGKLMETYCSQKHTRLDYIGDSKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 GIPMSMKNEMPISQLLMIIAPSLGFVLFALFVAFLLRGKLMETYCSQKHTRLDYIGDSKN
280 290 300 310 320 330
370
pF1KE2 VLNDVQHGREDEDGLFTL
::::::::::::::::::
CCDS54 VLNDVQHGREDEDGLFTL
340 350
>>CCDS43392.1 HAVCR1 gene_id:26762|Hs108|chr5 (364 aa)
initn: 357 init1: 357 opt: 449 Z-score: 412.7 bits: 85.0 E(32554): 1.2e-16
Smith-Waterman score: 449; 37.5% identity (60.5% similar) in 256 aa overlap (33-281:29-272)
10 20 30 40 50 60
pF1KE2 KEPLILWLMIEFWWLYLTPVTSETVVTEVLGHRVTLPCLYSSWSHNSNSMCWGKDQCPYS
: ::::: ::. .::::.. .:
CCDS43 MHPQVVILSLILHLADSVAGSVKVGGEAGPSVTLPCHYSG---AVTSMCWNRGSCSLF
10 20 30 40 50
70 80 90 100 110 120
pF1KE2 GCKEALIRTDGMRVTSRKSAKYRLQGTIPRGDVSLTILNPSESDSGVYCCRIEVPGWFND
:..... :.: .:: ::...:.: : . : :::::: : . :::::::::.: :::::
CCDS43 TCQNGIVWTNGTHVTYRKDTRYKLLGDLSRRDVSLTIENTAVSDSGVYCCRVEHRGWFND
60 70 80 90 100 110
130 140 150 160 170
pF1KE2 VKINVRLNLQRASTTTHRTATT----TTRRTTTTSPTTTR-QMTTTPAALPTTVVTTPDL
.::.: :.. ..:: .:: :: ::.:: :::: :::.:.. :... :
CCDS43 MKITVSLEIVPPKVTTTPIVTTVPTVTTVRTSTTVPTTTTVPMTTVPTTTVPTTMSIP--
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE2 TTGTPLQMTTIAVFTTANTCLSLTPSTLPEEATGLLTPEPSKEGPILTAESETVLPSDSW
:: : : :... :.. : :. .: .: . : : : . : .. :: :
CCDS43 TTTTVLTTMTVSTTTSVPTTTSIPTTTSVPVTTTVSTFVPPMPLPRQNHEPVATSPS-SP
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE2 SSAESTSADTVLLTSKESKVWDLPSTSHVSMWKT--SDSVSSPQPGASDTAVPEQNKTTK
. ::. :. .. . :..: . . : .:.:. . :
CCDS43 QPAETHP------TTLQGAIRREPTSSPLYSYTTDGNDTVTESSDGLWNNNQTQLFLEHS
240 250 260 270 280
300 310 320 330 340 350
pF1KE2 TGQMDGIPMSMKNEMPISQLLMIIAPSLGFVLFALFVAFLLRGKLMETYCSQKHTRLDYI
CCDS43 LLTANTTKGIYAGVCISVLVLLALLGVIIAKKYFFKKEVQQLSVSFSSLQIKALQNAVEK
290 300 310 320 330 340
>>CCDS78076.1 HAVCR1 gene_id:26762|Hs108|chr5 (401 aa)
initn: 357 init1: 357 opt: 449 Z-score: 412.0 bits: 85.0 E(32554): 1.3e-16
Smith-Waterman score: 449; 37.5% identity (60.5% similar) in 256 aa overlap (33-281:29-272)
10 20 30 40 50 60
pF1KE2 KEPLILWLMIEFWWLYLTPVTSETVVTEVLGHRVTLPCLYSSWSHNSNSMCWGKDQCPYS
: ::::: ::. .::::.. .:
CCDS78 MHPQVVILSLILHLADSVAGSVKVGGEAGPSVTLPCHYSG---AVTSMCWNRGSCSLF
10 20 30 40 50
70 80 90 100 110 120
pF1KE2 GCKEALIRTDGMRVTSRKSAKYRLQGTIPRGDVSLTILNPSESDSGVYCCRIEVPGWFND
:..... :.: .:: ::...:.: : . : :::::: : . :::::::::.: :::::
CCDS78 TCQNGIVWTNGTHVTYRKDTRYKLLGDLSRRDVSLTIENTAVSDSGVYCCRVEHRGWFND
60 70 80 90 100 110
130 140 150 160 170
pF1KE2 VKINVRLNLQRASTTTHRTATT----TTRRTTTTSPTTTR-QMTTTPAALPTTVVTTPDL
.::.: :.. ..:: .:: :: ::.:: :::: :::.:.. :... :
CCDS78 MKITVSLEIVPPKVTTTPIVTTVPTVTTVRTSTTVPTTTTVPMTTVPTTTVPTTMSIP--
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE2 TTGTPLQMTTIAVFTTANTCLSLTPSTLPEEATGLLTPEPSKEGPILTAESETVLPSDSW
:: : : :... :.. : :. .: .: . : : : . : .. :: :
CCDS78 TTTTVLTTMTVSTTTSVPTTTSIPTTTSVPVTTTVSTFVPPMPLPRQNHEPVATSPS-SP
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE2 SSAESTSADTVLLTSKESKVWDLPSTSHVSMWKT--SDSVSSPQPGASDTAVPEQNKTTK
. ::. :. .. . :..: . . : .:.:. . :
CCDS78 QPAETHP------TTLQGAIRREPTSSPLYSYTTDGNDTVTESSDGLWNNNQTQLFLEHS
240 250 260 270 280
300 310 320 330 340 350
pF1KE2 TGQMDGIPMSMKNEMPISQLLMIIAPSLGFVLFALFVAFLLRGKLMETYCSQKHTRLDYI
CCDS78 LLTANTTKGIYAGVCISVLVLLALLGVIIAKMFHLAAFKLKLCKMQLKRKSKQKTISTLR
290 300 310 320 330 340
>>CCDS4333.1 HAVCR2 gene_id:84868|Hs108|chr5 (301 aa)
initn: 276 init1: 199 opt: 333 Z-score: 310.9 bits: 65.9 E(32554): 5.3e-11
Smith-Waterman score: 333; 35.6% identity (60.3% similar) in 174 aa overlap (17-189:15-180)
10 20 30 40 50
pF1KE2 MSKEPLILWLMIEFWWLYLTPVTSETVVTEVLGHRVTLPCLYSSWSH-NSNSMCWGKDQC
: : .::. .:. . :::.:. . : .:::: :
CCDS43 MFSHLPFDCVLLLLLLLLTRSSEVEYRAEVGQNAYLPCFYTPAAPGNLVPVCWGKGAC
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 PYSGCKEALIRTDGMRVTSRKSAKYRLQGTIPRGDVSLTILNPSESDSGVYCCRIEVPGW
: : ....::: : .. ...: :.: . .::::::: : . .:::.:::::..::
CCDS43 PVFECGNVVLRTD-ERDVNYWTSRYWLNGDFRKGDVSLTIENVTLADSGIYCCRIQIPGI
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE2 FNDVKINVRLNLQRASTTTHRTATTTTRRTTTTSPTTTRQMTTTPAALPTTVVTTPDLTT
.:: :.:..: .. :..: : : : :.. : :: : . . ::..
CCDS43 MNDEKFNLKLVIKPAKVTP---APTRQRDFTAAFPRMLTTRGHGPAETQT-LGSLPDINL
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE2 GTPLQMTTIAVFTTANTCLSLTPSTLPEEATGLLTPEPSKEGPILTAESETVLPSDSWSS
:..:.:
CCDS43 ---TQISTLANELRDSRLANDLRDSGATIRIGIYIGAGICAGLALALIFGALIFKWYSHS
180 190 200 210 220 230
378 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 12:24:29 2016 done: Thu Nov 3 12:24:29 2016
Total Scan time: 2.990 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]