FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE2425, 329 aa
  1>>>pF1KE2425 329 - 329 aa - 329 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.4396+/-0.000309; mu= 21.0644+/- 0.019
 mean_var=63.6194+/-13.160, 0's: 0 Z-trim(117.0): 3  B-trim: 1668 in 1/50
 Lambda= 0.160798
 statistics sampled from 28597 (28600) to 28597 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.701), E-opt: 0.2 (0.335), width:  16
 Scan time:  6.940

The best scores are:                                      opt bits E(85289)
NP_005124 (OMIM: 605385) CAAX prenyl protease 2 is ( 329) 2269 534.6 1.1e-151
NP_001027450 (OMIM: 605385) CAAX prenyl protease 2 ( 225) 1562 370.5 1.9e-102


>>NP_005124 (OMIM: 605385) CAAX prenyl protease 2 isofor  (329 aa)
 initn: 2269 init1: 2269 opt: 2269  Z-score: 2844.6  bits: 534.6 E(85289): 1.1e-151
Smith-Waterman score: 2269; 100.0% identity (100.0% similar) in 329 aa overlap (1-329:1-329)

               10        20        30        40        50        60
pF1KE2 MAALGGDGLRLLSVSRPERPPESAALGGLGPGLCCWVSVFSCLSLACSYVGSLYVWKSEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MAALGGDGLRLLSVSRPERPPESAALGGLGPGLCCWVSVFSCLSLACSYVGSLYVWKSEL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 PRDHPAVIKRRFTSVLVVSSLSPLCVLLWRELTGIQPGTSLLTLMGFRLEGIFPAALLPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PRDHPAVIKRRFTSVLVVSSLSPLCVLLWRELTGIQPGTSLLTLMGFRLEGIFPAALLPL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 LLTMILFLGPLMQLSMDCPCDLADGLKVVLAPRSWARCLTDMRWLRNQVIAPLTEELVFR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LLTMILFLGPLMQLSMDCPCDLADGLKVVLAPRSWARCLTDMRWLRNQVIAPLTEELVFR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 ACMLPMLAPCMGLGPAVFTCPLFFGVAHFHHIIEQLRFRQSSVGNIFLSAAFQFSYTAVF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ACMLPMLAPCMGLGPAVFTCPLFFGVAHFHHIIEQLRFRQSSVGNIFLSAAFQFSYTAVF
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE2 GAYTAFLFIRTGHLIGPVLCHSFCNYMGFPAVCAALEHPQRRPLLAGYALGVGLFLLLLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GAYTAFLFIRTGHLIGPVLCHSFCNYMGFPAVCAALEHPQRRPLLAGYALGVGLFLLLLQ
              250       260       270       280       290       300

              310       320         
pF1KE2 PLTDPKLYGSLPLCVLLERAGDSEAPLCS
       :::::::::::::::::::::::::::::
NP_005 PLTDPKLYGSLPLCVLLERAGDSEAPLCS
              310       320         

>>NP_001027450 (OMIM: 605385) CAAX prenyl protease 2 iso  (225 aa)
 initn: 1562 init1: 1562 opt: 1562  Z-score: 1960.3  bits: 370.5 E(85289): 1.9e-102
Smith-Waterman score: 1562; 100.0% identity (100.0% similar) in 225 aa overlap (105-329:1-225)

           80        90       100       110       120       130    
pF1KE2 VLVVSSLSPLCVLLWRELTGIQPGTSLLTLMGFRLEGIFPAALLPLLLTMILFLGPLMQL
                                     ::::::::::::::::::::::::::::::
NP_001                               MGFRLEGIFPAALLPLLLTMILFLGPLMQL
                                             10        20        30

          140       150       160       170       180       190    
pF1KE2 SMDCPCDLADGLKVVLAPRSWARCLTDMRWLRNQVIAPLTEELVFRACMLPMLAPCMGLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SMDCPCDLADGLKVVLAPRSWARCLTDMRWLRNQVIAPLTEELVFRACMLPMLAPCMGLG
               40        50        60        70        80        90

          200       210       220       230       240       250    
pF1KE2 PAVFTCPLFFGVAHFHHIIEQLRFRQSSVGNIFLSAAFQFSYTAVFGAYTAFLFIRTGHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PAVFTCPLFFGVAHFHHIIEQLRFRQSSVGNIFLSAAFQFSYTAVFGAYTAFLFIRTGHL
              100       110       120       130       140       150

          260       270       280       290       300       310    
pF1KE2 IGPVLCHSFCNYMGFPAVCAALEHPQRRPLLAGYALGVGLFLLLLQPLTDPKLYGSLPLC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGPVLCHSFCNYMGFPAVCAALEHPQRRPLLAGYALGVGLFLLLLQPLTDPKLYGSLPLC
              160       170       180       190       200       210

          320         
pF1KE2 VLLERAGDSEAPLCS
       :::::::::::::::
NP_001 VLLERAGDSEAPLCS
              220     




329 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Mon Nov  7 19:53:08 2016 done: Mon Nov  7 19:53:09 2016
 Total Scan time:  6.940 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]