FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE2414, 151 aa
  1>>>pF1KE2414 151 - 151 aa - 151 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.9889+/-0.000285; mu= -1.7212+/- 0.018
 mean_var=228.2219+/-45.872, 0's: 0 Z-trim(125.5): 4  B-trim: 0 in 0/58
 Lambda= 0.084898
 statistics sampled from 49469 (49473) to 49469 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.847), E-opt: 0.2 (0.58), width:  16
 Scan time:  6.170

The best scores are:                                      opt bits E(85289)
NP_057223 (OMIM: 616244,616710) coiled-coil-helix- ( 151) 1030 136.9 1.2e-32
NP_001307256 (OMIM: 616244,616710) coiled-coil-hel ( 168) 1020 135.7   3e-32
NP_998885 (OMIM: 615048,615903,615911,616209) coil ( 142)  517 74.1 9.1e-14
NP_001288268 (OMIM: 615048,615903,615911,616209) c ( 149)  512 73.5 1.4e-13


>>NP_057223 (OMIM: 616244,616710) coiled-coil-helix-coil  (151 aa)
 initn: 1030 init1: 1030 opt: 1030  Z-score: 707.3  bits: 136.9 E(85289): 1.2e-32
Smith-Waterman score: 1030; 100.0% identity (100.0% similar) in 151 aa overlap (1-151:1-151)

               10        20        30        40        50        60
pF1KE2 MPRGSRSRTSRMAPPASRAPQMRAAPRPAPVAQPPAAAPPSAVGSSAAAPRQPGLMAQMA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MPRGSRSRTSRMAPPASRAPQMRAAPRPAPVAQPPAAAPPSAVGSSAAAPRQPGLMAQMA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 TTAAGVAVGSAVGHTLGHAITGGFSGGSNAEPARPDITYQEPQGTQPAQQQQPCLYEIKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 TTAAGVAVGSAVGHTLGHAITGGFSGGSNAEPARPDITYQEPQGTQPAQQQQPCLYEIKQ
               70        80        90       100       110       120

              130       140       150 
pF1KE2 FLECAQNQGDIKLCEGFNEVLKQCRLANGLA
       :::::::::::::::::::::::::::::::
NP_057 FLECAQNQGDIKLCEGFNEVLKQCRLANGLA
              130       140       150 

>>NP_001307256 (OMIM: 616244,616710) coiled-coil-helix-c  (168 aa)
 initn: 1020 init1: 1020 opt: 1020  Z-score: 700.1  bits: 135.7 E(85289): 3e-32
Smith-Waterman score: 1020; 100.0% identity (100.0% similar) in 149 aa overlap (1-149:1-149)

               10        20        30        40        50        60
pF1KE2 MPRGSRSRTSRMAPPASRAPQMRAAPRPAPVAQPPAAAPPSAVGSSAAAPRQPGLMAQMA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPRGSRSRTSRMAPPASRAPQMRAAPRPAPVAQPPAAAPPSAVGSSAAAPRQPGLMAQMA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 TTAAGVAVGSAVGHTLGHAITGGFSGGSNAEPARPDITYQEPQGTQPAQQQQPCLYEIKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTAAGVAVGSAVGHTLGHAITGGFSGGSNAEPARPDITYQEPQGTQPAQQQQPCLYEIKQ
               70        80        90       100       110       120

              130       140       150                  
pF1KE2 FLECAQNQGDIKLCEGFNEVLKQCRLANGLA                 
       :::::::::::::::::::::::::::::                   
NP_001 FLECAQNQGDIKLCEGFNEVLKQCRLANGRIGLMKKFNLERWKISSHN
              130       140       150       160        

>>NP_998885 (OMIM: 615048,615903,615911,616209) coiled-c  (142 aa)
 initn: 784 init1: 290 opt: 517  Z-score: 368.1  bits: 74.1 E(85289): 9.1e-14
Smith-Waterman score: 529; 57.2% identity (75.0% similar) in 152 aa overlap (1-151:1-139)

               10        20        30        40        50        60
pF1KE2 MPRGSRSRTSRMAPPASRAPQMRAAPRPAPVAQPPAAAPPSAVGSSAAAPRQPGLMAQMA
       ::::::: .::   :::: :        :: :.:::  ::::.. . :   :::::::::
NP_998 MPRGSRSAASR---PASR-P-------AAPSAHPPAHPPPSAAAPAPAPSGQPGLMAQMA
               10                   20        30        40         

               70        80        90       100       110          
pF1KE2 TTAAGVAVGSAVGHTLGHAITGGFSGGSNAEPARPDITYQEPQGTQPAQQQQ-PCLYEIK
       ::::::::::::::..: :.::.:::::. ::..: .  : :  . :   :. :: :::.
NP_998 TTAAGVAVGSAVGHVMGSALTGAFSGGSS-EPSQPAVQ-QAPTPAAPQPLQMGPCAYEIR
      50        60        70         80         90       100       

     120       130       140       150    
pF1KE2 QFLECAQNQGDIKLCEGFNEVLKQCRLANGLA   
       :::.:. .:.:..:::::.:.::::.  .::.   
NP_998 QFLDCSTTQSDLSLCEGFSEALKQCKYYHGLSSLP
       110       120       130       140  

>>NP_001288268 (OMIM: 615048,615903,615911,616209) coile  (149 aa)
 initn: 635 init1: 280 opt: 512  Z-score: 364.5  bits: 73.5 E(85289): 1.4e-13
Smith-Waterman score: 524; 55.7% identity (72.2% similar) in 158 aa overlap (1-151:1-146)

               10        20        30        40        50        60
pF1KE2 MPRGSRSRTSRMAPPASRAPQMRAAPRPAPVAQPPAAAPPSAVGSSAAAPRQPGLMAQMA
       ::::::: .::   :::: :        :: :.:::  ::::.. . :   :::::::::
NP_001 MPRGSRSAASR---PASR-P-------AAPSAHPPAHPPPSAAAPAPAPSGQPGLMAQMA
               10                   20        30        40         

               70        80        90       100          110       
pF1KE2 TTAAGVAVGSAVGHTLGHAITGGFSGGSNAEPARPDITYQ---EPQGTQPAQQQQ----P
       ::::::::::::::..: :.::.:::::. ::..: .       ::.  ::  :     :
NP_001 TTAAGVAVGSAVGHVMGSALTGAFSGGSS-EPSQPAVQQPLALYPQAPTPAAPQPLQMGP
      50        60        70         80        90       100        

           120       130       140       150    
pF1KE2 CLYEIKQFLECAQNQGDIKLCEGFNEVLKQCRLANGLA   
       : :::.:::.:. .:.:..:::::.:.::::.  .::.   
NP_001 CAYEIRQFLDCSTTQSDLSLCEGFSEALKQCKYYHGLSSLP
      110       120       130       140         




151 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 19:03:08 2016 done: Sat Nov  5 19:03:08 2016
 Total Scan time:  6.170 Total Display time: -0.030

Function used was FASTA [36.3.4 Apr, 2011]