Result of FASTA (omim) for
pFN21AE2412
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2412, 176 aa
1>>>pF1KE2412 176 - 176 aa - 176 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.3138+/-0.000267; mu= 10.2342+/- 0.017
mean_var=109.0495+/-22.141, 0's: 0 Z-trim(122.3): 11 B-trim: 363 in 1/60
Lambda= 0.122818
statistics sampled from 40228 (40240) to 40228 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.789), E-opt: 0.2 (0.472), width: 16
Scan time: 6.290
The best scores are: opt bits E(85289)
NP_443118 (OMIM: 609684) protein MAL2 [Homo sapien ( 176) 1206 222.9 2.1e-58
XP_011515109 (OMIM: 609684) PREDICTED: protein MAL ( 119) 514 100.2 1.2e-21
NP_002362 (OMIM: 188860) myelin and lymphocyte pro ( 153) 293 61.1 9.2e-10
NP_005425 (OMIM: 602022) MAL-like protein [Homo sa ( 153) 293 61.1 9.2e-10
XP_011510111 (OMIM: 602022) PREDICTED: MAL-like pr ( 149) 240 51.7 6.1e-07
NP_071883 (OMIM: 188860) myelin and lymphocyte pro ( 111) 237 51.1 7e-07
NP_849199 (OMIM: 607891) CKLF-like MARVEL transmem ( 173) 182 41.5 0.00085
NP_057077 (OMIM: 600340) plasmolipin [Homo sapiens ( 182) 177 40.6 0.0016
>>NP_443118 (OMIM: 609684) protein MAL2 [Homo sapiens] (176 aa)
initn: 1206 init1: 1206 opt: 1206 Z-score: 1169.7 bits: 222.9 E(85289): 2.1e-58
Smith-Waterman score: 1206; 100.0% identity (100.0% similar) in 176 aa overlap (1-176:1-176)
10 20 30 40 50 60
pF1KE2 MSAGGASVPPPPNPAVSFPPPRVTLPAGPDILRTYSGAFVCLEILFGGLVWILVASSNVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 MSAGGASVPPPPNPAVSFPPPRVTLPAGPDILRTYSGAFVCLEILFGGLVWILVASSNVP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LPLLQGWVMFVSVTAFFFSLLFLGMFLSGMVAQIDANWNFLDFAYHFTVFVFYFGAFLLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 LPLLQGWVMFVSVTAFFFSLLFLGMFLSGMVAQIDANWNFLDFAYHFTVFVFYFGAFLLE
70 80 90 100 110 120
130 140 150 160 170
pF1KE2 AAATSLHDLHCNTTITGQPLLSDNQYNINVAASIFAFMTTACYGCSLGLALRRWRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 AAATSLHDLHCNTTITGQPLLSDNQYNINVAASIFAFMTTACYGCSLGLALRRWRP
130 140 150 160 170
>>XP_011515109 (OMIM: 609684) PREDICTED: protein MAL2 is (119 aa)
initn: 536 init1: 514 opt: 514 Z-score: 509.4 bits: 100.2 E(85289): 1.2e-21
Smith-Waterman score: 699; 67.6% identity (67.6% similar) in 176 aa overlap (1-176:1-119)
10 20 30 40 50 60
pF1KE2 MSAGGASVPPPPNPAVSFPPPRVTLPAGPDILRTYSGAFVCLEILFGGLVWILVASSNVP
::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSAGGASVPPPPNPAVSFPPPRVTLPAGPDILRTYSGAFVCLEI----------------
10 20 30 40
70 80 90 100 110 120
pF1KE2 LPLLQGWVMFVSVTAFFFSLLFLGMFLSGMVAQIDANWNFLDFAYHFTVFVFYFGAFLLE
:::::::::::::::::::
XP_011 -----------------------------------------DFAYHFTVFVFYFGAFLLE
50 60
130 140 150 160 170
pF1KE2 AAATSLHDLHCNTTITGQPLLSDNQYNINVAASIFAFMTTACYGCSLGLALRRWRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAATSLHDLHCNTTITGQPLLSDNQYNINVAASIFAFMTTACYGCSLGLALRRWRP
70 80 90 100 110
>>NP_002362 (OMIM: 188860) myelin and lymphocyte protein (153 aa)
initn: 342 init1: 210 opt: 293 Z-score: 296.2 bits: 61.1 E(85289): 9.2e-10
Smith-Waterman score: 338; 40.1% identity (64.5% similar) in 152 aa overlap (24-175:11-151)
10 20 30 40 50 60
pF1KE2 MSAGGASVPPPPNPAVSFPPPRVTLPAGPDILRTYSGAFVCLEILFGGLVWILVASSNVP
:::.: ... : . .:..:::::::::::: ::
NP_002 MAPAAATGGSTLPSGFSVFTTLPDLLFIFEFIFGGLVWILVASSLVP
10 20 30 40
70 80 90 100 110 120
pF1KE2 LPLLQGWVMFVSVTAFFFSLLFLGMFLSGMVAQIDANWNFLDFAYHFTVFVFYFGAFLLE
::.::::::::: : . .. ... : . ...: :: ::: :. .::..: .::
NP_002 WPLVQGWVMFVSVFCFVATTTLIILYIIGAHGG-ETSWVTLDAAYHCTAALFYLSASVLE
50 60 70 80 90 100
130 140 150 160 170
pF1KE2 AAATSLHDLHCNTTITGQPLLSDNQYNINVAASIFAFMTTACYGCSLGLALRRWRP
: :: :: : .. .:. :.:: .:....: : ..: ::.
NP_002 ALAT----------ITMQDGFTYRHYHENIAAVVFSYIATLLYVVHAVFSLIRWKSS
110 120 130 140 150
>>NP_005425 (OMIM: 602022) MAL-like protein [Homo sapien (153 aa)
initn: 262 init1: 197 opt: 293 Z-score: 296.2 bits: 61.1 E(85289): 9.2e-10
Smith-Waterman score: 337; 40.5% identity (66.0% similar) in 153 aa overlap (11-163:4-143)
10 20 30 40 50 60
pF1KE2 MSAGGASVPPPPNPAVSFPPPRVTLPAGPDILRTYSGAFVCLEILFGGLVWILVASSNVP
: ::.:. : : :.: .. : :: :..:: ::: .::....
NP_005 MASPDPPATSYAPSDV--PSGVALFLTIPFAFFLPELIFGFLVWTMVAATHIV
10 20 30 40 50
70 80 90 100 110 120
pF1KE2 LPLLQGWVMFVSVTAFFFSLLFLGMFLSGMVAQIDANWNFLDFAYHFTVFVFYFGAFLLE
::::::::.::.:.:..::.:: .: :. .... : :: :: :. ..:..: .:.
NP_005 YPLLQGWVMYVSLTSFLISLMFLLSYLFGFYKRFES-WRVLDSLYHGTTGILYMSAAVLQ
60 70 80 90 100 110
130 140 150 160 170
pF1KE2 AAATSLHDLHCNTTITGQPLLSDNQYNINVAASIFAFMTTACYGCSLGLALRRWRP
. :: :... ::. : :: :::.:::..: :
NP_005 VHAT----------IVSEKLLDPRIYYINSAASFFAFIATLLYILHAFSIYYH
120 130 140 150
>>XP_011510111 (OMIM: 602022) PREDICTED: MAL-like protei (149 aa)
initn: 250 init1: 185 opt: 240 Z-score: 245.6 bits: 51.7 E(85289): 6.1e-07
Smith-Waterman score: 284; 41.7% identity (70.0% similar) in 120 aa overlap (44-163:31-139)
20 30 40 50 60 70
pF1KE2 PAVSFPPPRVTLPAGPDILRTYSGAFVCLEILFGGLVWILVASSNVPLPLLQGWVMFVSV
..:: ::: .::.... ::::::::.::.
XP_011 MEKLTEDSRKKKKGAGIFGKETRIQNTTKLLIFGFLVWTMVAATHIVYPLLQGWVMYVSL
10 20 30 40 50 60
80 90 100 110 120 130
pF1KE2 TAFFFSLLFLGMFLSGMVAQIDANWNFLDFAYHFTVFVFYFGAFLLEAAATSLHDLHCNT
:.:..::.:: .: :. .... : :: :: :. ..:..: .:.. :
XP_011 TSFLISLMFLLSYLFGFYKRFES-WRVLDSLYHGTTGILYMSAAVLQVHA----------
70 80 90 100
140 150 160 170
pF1KE2 TITGQPLLSDNQYNINVAASIFAFMTTACYGCSLGLALRRWRP
::... ::. : :: :::.:::..: :
XP_011 TIVSEKLLDPRIYYINSAASFFAFIATLLYILHAFSIYYH
110 120 130 140
>>NP_071883 (OMIM: 188860) myelin and lymphocyte protein (111 aa)
initn: 233 init1: 210 opt: 237 Z-score: 244.5 bits: 51.1 E(85289): 7e-07
Smith-Waterman score: 237; 41.7% identity (66.7% similar) in 96 aa overlap (24-119:11-105)
10 20 30 40 50 60
pF1KE2 MSAGGASVPPPPNPAVSFPPPRVTLPAGPDILRTYSGAFVCLEILFGGLVWILVASSNVP
:::.: ... : . .:..:::::::::::: ::
NP_071 MAPAAATGGSTLPSGFSVFTTLPDLLFIFEFIFGGLVWILVASSLVP
10 20 30 40
70 80 90 100 110 120
pF1KE2 LPLLQGWVMFVSVTAFFFSLLFLGMFLSGMVAQIDANWNFLDFAYHFTVFVFYFGAFLLE
::.::::::::: : . .. ... : . ...: : :.: :.. ..: :
NP_071 WPLVQGWVMFVSVFCFVATTTLIILYIIGAHGG-ETSWVTLVFSYIATLLYVVHAVFSLI
50 60 70 80 90 100
130 140 150 160 170
pF1KE2 AAATSLHDLHCNTTITGQPLLSDNQYNINVAASIFAFMTTACYGCSLGLALRRWRP
NP_071 RWKSS
110
>>NP_849199 (OMIM: 607891) CKLF-like MARVEL transmembran (173 aa)
initn: 205 init1: 132 opt: 182 Z-score: 189.2 bits: 41.5 E(85289): 0.00085
Smith-Waterman score: 228; 27.0% identity (63.8% similar) in 163 aa overlap (15-175:20-168)
10 20 30 40 50
pF1KE2 MSAGGASVPPPPNPAVSFPPPRVTLPAGPDILRTYSGAFVCLEILFGGLVWILVA
: .: .. ..::: : .. ::..: ::: :.:
NP_849 MEEPQRARSHTVTTTASSFAENFSTSSSSFAYDREFLRTLPGFLIVAEIVLGLLVWTLIA
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 SSNV-PLPLLQGWVMFVSVTAFFFSLLFLGMFLSGMVAQI-DANWNFLDFAYHFTVFVFY
... .: . ::::::.: . ....:: .... ..: .. :. . . .. ..::.:
NP_849 GTEYFRVPAF-GWVMFVAVFYWVLTVFFLIIYITMTYTRIPQVPWTTVGLCFNGSAFVLY
70 80 90 100 110
120 130 140 150 160 170
pF1KE2 FGAFLLEAAATSLHDLHCNTTITGQPLLSDNQYNINVAASIFAFMTTACYGCSLGLALRR
..: ...:...: : .....: .:.:.:::..: ::. . ...
NP_849 LSAAVVDASSVS-------------PERDSHNFNSWAASSFFAFLVTICYAGNTYFSFIA
120 130 140 150 160
pF1KE2 WRP
::
NP_849 WRSRTIQ
170
>>NP_057077 (OMIM: 600340) plasmolipin [Homo sapiens] (182 aa)
initn: 193 init1: 134 opt: 177 Z-score: 184.1 bits: 40.6 E(85289): 0.0016
Smith-Waterman score: 217; 28.7% identity (62.0% similar) in 150 aa overlap (29-175:28-166)
10 20 30 40 50
pF1KE2 MSAGGASVPPPPNPAVSFPPPRVTLPAGPDI--LRTYSGAFVCLEILFGGLVWILVASSN
::. .:. ::.. :....: ::: :.:..
NP_057 MAEFPSKVSTRTSSPAQGAEASVSALRPDLGFVRSRLGALMLLQLVLGLLVWALIADTP
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 VPLPLLQGWVMFVSVTAFFFSLLFLGMFLSGMVAQID-ANWNFLDFAYHFTVFVFYFGAF
: ::::::.: .. ........: . .. . : .. . ..... :.:. ::
NP_057 YHLYPAYGWVMFVAVFLWLVTIVLFNLYLFQLHMKLYMVPWPLVLMIFNISATVLYITAF
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE2 LLEAAATSLHDLHCNTTITGQPLLSDNQYNINVAASIFAFMTTACYGCSLGLALRRWRP
. .::..: :.. : :: .:::.:: .. :: : .. . ::
NP_057 IACSAAVDL------TSLRGT-----RPYNQRAAASFFACLVMIAYGVSAFFSYQAWRGV
120 130 140 150 160
NP_057 GSNAATSQMAGGYA
170 180
176 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 19:20:48 2016 done: Sat Nov 5 19:20:48 2016
Total Scan time: 6.290 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]